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Number of items: 19.

Fernandez, F J; de Vries, D; Peña-Soler, E; Coll, M; Christen, P; Gehring, H; Vega, M C (2012). Structure and mechanism of a cysteine sulfinate desulfinase engineered on the aspartate aminotransferase scaffold. Biochimica et Biophysica Acta, 1824(2):339-349.

Wu, F; Christen, P; Gehring, H (2011). A novel approach to inhibit intracellular vitamin B6-dependent enzymes: proof of principle with human and plasmodium ornithine decarboxylase and human histidine decarboxylase. FASEB Journal, 25(7):2109-2122.

Sharma, S K; Goloubinoff, P; Christen, P (2011). Non-native proteins as newly-identified targets of heavy metals and metalloids. In: Banfalvi, G. Cellular Effects of Heavy Metals. Heidelberg: Springer, 263-274.

Burkart, V; Siegenthaler, R K; Blasius, E; Vandenbroeck, K; Alloza, I; Fingberg, W; Schloot, N C; Christen, P; Kolb, H (2010). High affinity binding of hydrophobic and autoantigenic regions of proinsulin to the 70 kDa chaperone DnaK. BMC Biochemistry, 11:44.

Sharma, S K; De los Rios, P; Christen, P; Lustig, A; Goloubinoff, P (2010). The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase. Nature chemical biology, 6(12):914-920.

Kochhar, S; Mouratou, B; Christen, P (2009). Amino acid analysis by precolumn derivatization with 1-fluoro-2,4-dinitrophenyl-5-L-alanine amide (Marfey agent). In: Walker, J M. The Protein Protocols Handbook. Totowa, NJ: Humana Press, 567-572.

Sharma, S K; Christen, P; Goloubinoff, P (2009). Disaggregating chaperones: an unfolding story. Current Protein and Peptide Science, 10(5):432-446.

Scocchi, M; Lüthy, C; Decarli, P; Mignogna, G; Christen, P; Gennaro, R (2009). The proline-rich antibacterial peptide Bac7 binds to and inhibits in vitro the molecular chaperone DnaK. International Journal of Peptide Research and Therapeutics, 15(2):147-155.

Sharma, S K; Goloubinoff, P; Christen, P (2008). Heavy metal ions are potent inhibitors of protein folding. Biochemical and Biophysical Research Communications (BBRC), 372(2):341-345.

Vacca, R A; Giannattasio, S; Capitani, G; Marra, E; Christen, P (2008). Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme. BMC Biochemistry, 9:17.

Fernandez, F J; Vega, M C; Lehmann, F; Sandmeier, E; Gehring, H; Christen, P; Wilmanns, M (2004). Structural studies of the catalytic reaction pathway of a hyperthermophilic histidinol-phosphate aminotransferase. Journal of Biological Chemistry, 279(20):21478-21488.

Koller, M F; Mohajeri, M H; Huber, M; Wollmer, M A; Roth Z'graggen, B V; Sandmeier, E; Moritz, E; Tracy, J; Nitsch, R M; Christen, P (2004). Active immunization of mice with an Abeta-Hsp70 vaccine. Neurodegenerative Diseases, 1(1):20-28.

Kasper, P; Christen, P; Gehring, H (2000). Empirical calculation of the relative free energies of peptide binding to the molecular chaperone DnaK. Proteins, 40(2):185-192.

Graber, R; Kasper, P; Malashkevich, V N; Strop, P; Gehring, H; Jansonius, J N; Christen, P (1999). Conversion of aspartate aminotransferase into an L-aspartate beta-decarboxylase by a triple active-site mutation. Journal of Biological Chemistry, 274(44):31203-1325.

Mouratou, B; Kasper, P; Gehring, H; Christen, P (1999). Conversion of tyrosine phenol-lyase to dicarboxylic amino acid beta-lyase, an enzyme not found in nature. Journal of Biological Chemistry, 274(3):1320-1325.

Kasper, P; Sterk, M; Christen, P; Gehring, H (1996). Molecular-dynamics simulation of domain movements in aspartate aminotransferase. FEBS Journal, 240(3):751-755.

Christen, P; Kasper, P; Gehring, H; Sterk, M (1996). Stereochemical constraint in the evolution of pyridoxal-5'-phosphate-dependent enzymes. A hypothesis. FEBS Letters, 389(1):12-14.

Graber, R; Kasper, P; Malashkevich, V N; Sandmeier, E; Berger, P; Gehring, H; Jansonius, J N; Christen, P (1995). Changing the reaction specificity of a pyridoxal-5'-phosphate-dependent enzyme. FEBS Journal, 232(2):686-690.

Malashkevich, V N; Jäger, J; Ziak, M; Sauder, U; Gehring, H; Christen, P; Jansonius, J N (1995). Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue. Biochemistry, 34(2):405-414.

This list was generated on Sun Sep 22 21:02:52 2019 CEST.