Maintenance Infos

Browse by Creators

Navigate back| Up a level
Export as
Number of items: 71.

Vayena, Effy; Gourna, E; Streuli, Jürg C; Hafen, E; Prainsack, B (2012). Experiences of early users of direct-to-consumer genomics in Switzerland: an exploratory study. Public health genomics, 15(6):352-362.

Aegerter-Wilmsen, T; Smith, A C; Christen, A J; Aegerter, C M; Hafen, E; Basler, K (2010). Exploring the effects of mechanical feedback on epithelial topology. Development, 137(3):499-506.

Köhler, K; Brunner, E; Guan, X L; Boucke, K; Greber, U F; Mohanty, S; Barth, J M; Wenk, M R; Hafen, E (2009). A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila. Autophagy, 5(7):980-990.

Goetze, S; Qeli, E; Mosimann, C; Staes, A; Gerrits, B; Roschitzki, B; Mohanty, S; Niederer, E M; Laczko, E; Timmerman, E; Lange, V; Hafen, E; Aebersold, R; Vandekerckhove, J; Basler, K; Ahrens, C H; Gevaert, K; Brunner, E (2009). Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster. PLoS Biology, 7(11):e1000236.

Brunner, E; Ahrens, C H; Mohanty, S; Baetschmann, H; Loevenich, S; Potthast, F; Deutsch, E W; Panse, C; de Lichtenberg, U; Rinner, O; Lee, H; Pedrioli, P G A; Malmstrom, J; Koehler, K; Schrimpf, S; Krijgsveld, J; Kregenow, F; Heck, A J R; Hafen, E; Schlapbach, R; Aebersold, R (2007). A high-quality catalog of the Drosophila melanogaster proteome. Nature Biotechnology, 25(5):576-583.

O'Reilly, A M; Ballew, A C; Miyazawa, B; Stocker, H; Hafen, E; Simon, M A (2006). Csk differentially regulates Src64 during distinct morphological events in Drosophila germ cells. Development, 133(14):2627-2638.

Nairz, K; Rottig, C; Rintelen, F; Zdobnov, E; Moser, M; Hafen, E (2006). Overgrowth caused by misexpression of a microRNA with dispensable wild-type function. Developmental Biology, 291(2):314-324.

Gingras, A C; Caballero, M; Zarske, M; Sanchez, Amy; Hazbun, T R; Fields, S; Sonenberg, N; Hafen, E; Raught, B; Aebersold, R (2005). A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. Molecular & Cellular Proteomics, 4(11):1725-1740.

Wittwer, F; Jaquenoud, M; Brogiolo, W; Zarske, M; Wüstemann, P; Fernandez, R; Stocker, H; Wymann, M P; Hafen, E (2005). Susi, a negative regulator of Drosophila PI3-kinase. Developmental Cell, 8(6):817-827.

Broughton, S J; Piper, M D W; Ikeya, T; Bass, T M; Jacobson, J; Driege, Y; Martinez, P; Hafen, E; Withers, D J; Leevers, S J; Partridge, L (2005). Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 102(8):3105-3110.

Frei, Christian; Galloni, M; Hafen, E; Edgar, B A (2005). The Drosophila mitochondrial ribosomal protein mRpL12 is required for Cyclin D/Cdk4-driven growth. The EMBO Journal, 24(3):623-634.

Reiling, J H; Doepfner, K T; Hafen, E; Stocker, H (2005). Diet-dependent effects of the Drosophila Mnk1/Mnk2 homolog Lk6 on growth via eIF4E. Current Biology, 15(1):24-30.

Zipperlen, P; Nairz, K; Rimann, I; Basler, K; Hafen, E; Hengartner, M; Hajnal, A (2005). A universal method for automated gene mapping. Genome Biology, 6(2):R19.

Desiere, F; Deutsch, E W; Nesvizhskii, A I; Mallick, P; King, N L; Eng, J K; Aderem, A; Boyle, R; Brunner, E; Donohoe, S; Fausto, N; Hafen, E; Hood, L; Katze, M G; Kennedy, K A; Kregenow, F; Lee, H; Lin, B; Martin, D; Ranish, J A; Rawlings, D J; Samelson, L E; Shiio, Y; Watts, J D; Wollscheid, B; Wright, M E; Yan, W; Yang, L; Yi, E C; Zhang, H; Aebersold, R (2005). Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry. Genome Biology, 6:R9.

Hafen, E (2004). Cancer, type 2 diabetes, and ageing: news from flies and worms. Swiss Medical Weekly, 134(49-50):711-719.

Brugarolas, J; Lei, K; Hurley, R L; Manning, B D; Reiling, J H; Hafen, E; Witters, L A; Ellisen, L W; Kaelin, W G (2004). Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. Genes and Development, 18(23):2893-2904.

Reiling, J H; Hafen, E (2004). The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila. Genes and Development, 18(23):2879-2892.

Giannakou, M E; Goss, M; Jünger, M A; Hafen, E; Leevers, S J; Partridge, L (2004). Long-lived Drosophila with overexpressed dFOXO in adult fat body. Science, 305(5682):361.

Egli, D; Hafen, E; Schaffner, Walter (2004). An efficient method to generate chromosomal rearrangements by targeted DNA double-strand breaks in Drosophila melanogaster. Genome Research, 14(7):1382-1393.

Ryder, E; Blows, F; Ashburner, M; Bautista-Llacer, R; Coulson, D; Drummond, Jenny; Webster, J; Gubb, D; Gunton, N; Johnson, G; O'Kane, C J; Huen, D; Sharma, P; Asztalos, Z; Baisch, H; Schulze, J; Kube, M; Kittlaus, K; Reuter, G; Maroy, P; Szidonya, J; Rasmuson-Lestander, A; Ekström, K; Dickson, B J; Hugentobler, C; Stocker, H; Hafen, E; Lepesant, J A; Pflugfelder, G O; Heisenberg, M; Mechler, B; Serras, F; Corominas, M; Schneuwly, S; Preat, T; Roote, J; Russell, S (2004). The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. Genetics, 167(2):797-813.

MacDougall, L K; Gagou, M E; Leevers, S J; Hafen, E; Waterfield, M D (2004). Targeted expression of the class II phosphoinositide 3-kinase in Drosophila melanogaster reveals lipid kinase-dependent effects on patterning and interactions with receptor signaling pathways. Molecular and Cellular Biology, 24(2):796-808.

Nairz, K; Zipperlen, P; Dearolf, C; Basler, K; Hafen, E (2004). A reverse genetic screen in Drosophila using a deletion-inducing mutagen. Genome Biology, 5(10):R83.

Hafen, E (2004). Interplay between growth factor and nutrient signaling: lessons from Drosophila TOR. In: Thomas, G; Sabatini, D M; Hall, M N. TOR. Target of Rapamycin. Berlin: Springer, 153-167.

Hafen, E; Stocker, H (2003). How are the sizes of cells, organs, and bodies controlled? PLoS Biology, 1(3):e86.

Rintelen, F; Hafen, E; Nairz, K (2003). The Drosophila dual-specificity ERK phosphatase DMKP3 cooperates with the ERK tyrosine phosphatase PTP-ER. Development, 130(15):3479-3490.

Garami, A; Zwartkruis, F J T; Nobukuni, T; Joaquin, M; Roccio, M; Stocker, H; Kozma, S C; Hafen, E; Bos, J L; Thomas, G (2003). Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2. Molecular Cell, 11(6):1457-1466.

Stocker, H; Radimerski, T; Schindelholz, B; Wittwer, F; Belawat, P; Daram, P; Breuer, S; Thomas, G; Hafen, E (2003). Rheb is an essential regulator of S6K in controlling cell growth in Drosophila. Nature Cell Biology, 5(6):559-565.

Oldham, S; Hafen, E (2003). Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends in Cell Biology, 13(2):79-85.

Egli, D; Selvaraj, A; Yepiskoposyan, H; Zhang, B; Hafen, E; Georgiev, Oleg; Schaffner, Walter (2003). Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis. The EMBO Journal, 22(1):100-108.

Jünger, M A; Rintelen, F; Stocker, H; Wasserman, J D; Végh, M; Radimerski, T; Greenberg, M E; Hafen, E (2003). The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. Journal of Biology, 2(3):20.

Oldham, S; Stocker, H; Laffargue, M; Wittwer, F; Wymann, M P; Hafen, E (2002). The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels. Development, 129(17):4103-4109.

Nairz, K; Stocker, H; Schindelholz, B; Hafen, E (2002). High-resolution SNP mapping by denaturing HPLC. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 99(16):10575-10580.

Ikeya, T; Galic, M; Belawat, P; Nairz, K; Hafen, E (2002). Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila. Current Biology, 12(15):1293-1300.

Clancy, D J; Gems, David; Hafen, E; Leevers, S J; Partridge, L (2002). Dietary restriction in long-lived dwarf flies. Science, 296(5566):313.

Stocker, H; Andjelkovic, M; Oldham, S; Laffargue, M; Wymann, M P; Hemmings, B A; Hafen, E (2002). Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB. Science, 295(5562):2088-2091.

Radimerski, T; Montagne, J; Rintelen, F; Stocker, H; van der Kaay, J; Downes, C P; Hafen, E; Thomas, G (2002). dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1. Nature Cell Biology, 4(3):251-255.

Bellotto, M; Bopp, D; Senti, K A; Burke, R; Deak, P; Maroy, P; Dickson, B J; Basler, K; Hafen, E (2002). Maternal-effect loci involved in Drosophila oogenesis and embryogenesis: P element-induced mutations on the third chromosome. International Journal of Developmental Biology, 41(1):149-157.

Rintelen, F; Stocker, H; Thomas, G; Hafen, E (2001). PDK1 regulates growth through Akt and S6K in Drosophila. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 98(26):15020-15025.

Morey, M; Serras, F; Baguñà, J; Hafen, E; Corominas, M (2001). Modulation of the Ras/MAPK signalling pathway by the redox function of selenoproteins in Drosophila melanogaster. Developmental Biology, 238(1):145-156.

Halfar, K; Rommel, C; Stocker, H; Hafen, E (2001). Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity. Development, 128(9):1687-1696.

Clancy, D J; Gems, D; Harshman, L G; Oldham, S; Stocker, H; Hafen, E; Leevers, S J; Partridge, L (2001). Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science, 292(5514):104-106.

Wittwer, F; van der Straten, A; Keleman, K; Dickson, B J; Hafen, E (2001). Lilliputian: an AF4/FMR2-related protein that controls cell identity and cell growth. Development, 128(5):791-800.

Brogiolo, W; Stocker, H; Ikeya, T; Rintelen, F; Fernandez, R; Hafen, E (2001). An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control. Current Biology, 11(4):213-221.

Oldham, S; Montagne, J; Radimerski, T; Thomas, G; Hafen, E (2000). Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin. Genes and Development, 14(21):2689-2694.

Stocker, H; Hafen, E (2000). Genetic control of cell size. Current Opinion in Genetics & Development, 10(5):529-535.

Oldham, S; Böhni, R; Stocker, H; Brogiolo, W; Hafen, E (2000). Genetic control of size in Drosophila. Philosophical Transactions of the Royal Society B: Biological Sciences, 355(1399):945-952.

Burke, R; Nellen, D; Bellotto, M; Hafen, E; Senti, K A; Dickson, B J; Basler, K (1999). Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells. Cell, 99(7):803-815.

Huang, H; Potter, C J; Tao, W; Li, D M; Brogiolo, W; Hafen, E; Sun, H; Xu, T (1999). PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development. Development, 126(23):5365-5372.

Montagne, J; Stewart, M J; Stocker, H; Hafen, E; Kozma, S C; Thomas, G (1999). Drosophila S6 kinase: a regulator of cell size. Science, 285(5436):2126-2129.

Böhni, R; Riesgo-Escovar, J R; Oldham, S; Brogiolo, W; Stocker, H; Andruss, B F; Beckingham, K; Hafen, E (1999). Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. Cell, 97(7):865-875.

Feldmann, P; Eicher, E N; Leevers, S J; Hafen, E; Hughes, D A (1999). Control of growth and differentiation by Drosophila RasGAP, a homolog of p120 Ras-GTPase-activating protein. Molecular and Cellular Biology, 19(3):1928-1937.

Brunner, E; Brunner, D; Fu, W; Hafen, E; Basler, K (1999). The dominant mutation Glazed is a gain-of-function allele of wingless that, similar to loss of APC, interferes with normal eye development. Developmental Biology, 206(2):178-188.

Eberle, K K; Zinsmaier, K E; Buchner, S; Gruhn, M; Jenni, M; Arnold, Christian; Leibold, C; Reisch, D; Walter, N; Hafen, E; Hofbauer, A; Pflugfelder, G O; Buchner, E (1998). Wide distribution of the cysteine string proteins in Drosophila tissues revealed by targeted mutagenesis. Cell and Tissue Research, 294(2):203-217.

Rommel, C; Hafen, E (1998). Ras--a versatile cellular switch. Current Opinion in Genetics & Development, 8(4):412-418.

Hafen, E (1998). Kinases and phosphatases--a marriage is consummated. Science, 280(5367):1212-1213.

Domínguez, M; Hafen, E (1997). Hedgehog directly controls initiation and propagation of retinal differentiation in the Drosophila eye. Genes and Development, 11(23):3254-3264.

Riesgo-Escovar, J R; Hafen, E (1997). Common and distinct roles of DFos and DJun during Drosophila development. Science, 278(5338):669-672.

Riesgo-Escovar, J R; Hafen, E (1997). Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure. Genes and Development, 11(13):1717-1727.

Rommel, C; Radziwill, G; Moelling, K; Hafen, E (1997). Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo. Mechanisms of Development, 64(1-2):95-104.

van der Straten, A; Rommel, C; Dickson, B J; Hafen, E (1997). The heat shock protein 83 (Hsp83) is required for Raf-mediated signalling in Drosophila. The EMBO Journal, 16(8):1961-1969.

Leevers, S J; Weinkove, D; MacDougall, L K; Hafen, E; Waterfield, M D (1996). The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. The EMBO Journal, 15(23):6584-6594.

Riesgo-Escovar, J R; Jenni, M; Fritz, A; Hafen, E (1996). The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye. Genes and Development, 10(21):2759-2768.

Oellers, N; Hafen, E (1996). Biochemical characterization of rolledSem, an activated form of Drosophila mitogen-activated protein kinase. Journal of Biological Chemistry, 271(40):24939-24944.

Raabe, T; Riesgo-Escovar, J R; Liu, X; Bausenwein, B S; Deak, P; Maroy, P; Hafen, E (1996). DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila. Cell, 85(6):911-920.

Domínguez, M; Brunner, M; Hafen, E; Basler, K (1996). Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus. Science, 272(5268):1621-1625.

Guillemin, K; Groppe, J; Ducker, K; Treisman, R; Hafen, E; Affolter, M; Krasnow, M A (1996). The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system. Development, 122(5):1353-1362.

Dickson, B J; van der Straten, A; Dominguez, M; Hafen, E (1996). Mutations modulating Raf signaling in Drosophila eye development. Genetics, 142(1):163-171.

Raabe, T; Olivier, J P; Dickson, B J; Liu, X; Gish, G D; Pawson, T; Hafen, E (1995). Biochemical and genetic analysis of the Drk SH2/SH3 adaptor protein of Drosophila. The EMBO Journal, 14(11):2509-2518.

Dickson, B J; Domínguez, M; van der Straten, A; Hafen, E (1995). Control of Drosophila photoreceptor cell fates by phyllopod, a novel nuclear protein acting downstream of the Raf kinase. Cell, 80(3):453-462.

Dambly-Chaudière, C; Jamet, E; Burri, M; Bopp, D; Basler, K; Hafen, E; Dumont, N; Spielmann, P; Ghysen, A; Noll, M (1992). The paired box gene pox neuro: a determinant of poly-innervated sense organs in Drosophila. Cell, 69(1):159-172.

Basler, K; Christen, B; Hafen, E (1991). Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye. Cell, 64(6):1069-1081.

This list was generated on Thu Jun 20 09:53:03 2019 CEST.