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Schütz, Anne K; Hornemann, Simone; Wälti, Marielle A; Greuter, Ladina; Tiberi, Cinzia; Cadalbert, Riccardo; Gantner, Matthias; Riek, Roland; Hammarström, Per; Nilsson, K Peter R; Böckmann, Anja; Aguzzi, Adriano; Meier, Beat H (2018). Binding of Polythiophenes to Amyloids: Structural Mapping of the Pharmacophore. ACS Chemical Neuroscience, 9(3):475-481.

Goniotaki, Despoina; Lakkaraju, Asvin K K; Shrivastava, Amulya N; Bakirci, Pamela; Sorce, Silvia; Senatore, Assunta; Marpakwar, Rajlakshmi; Hornemann, Simone; Gasparini, Fabrizio; Triller, Antoine; Aguzzi, Adriano (2017). Inhibition of group-I metabotropic glutamate receptors protects against prion toxicity. PLoS Pathogens, 13(11):e1006733.

Pfammatter, Manuela; Andreasen, Maria; Meisl, Georg; Taylor, Christopher G; Adamcik, Jozef; Bolisetty, Sreenath; Sanchez-Ferrer, Antoni; Klenerman, David; Dobson, Christopher M; Mezzenga, Raffaele; Knowles, Tuomas P J; Aguzzi, Adriano A; Hornemann, Simone (2017). Absolute Quantification of Amyloid Propagons by Digital Microfluidics. Analytical Chemistry, 89(22):12306-12313.

Ballmer, Boris A; Moos, Rita; Liberali, Prisca; Pelkmans, Lucas; Hornemann, Simone; Aguzzi, Adriano (2017). Modifiers of prion protein biogenesis and recycling identified by a highly-parallel endocytosis kinetics assay. Journal of Biological Chemistry, 292(20):8356-8368.

Leske, Henning; Hornemann, Simone; Herrmann, Uli Simon; Zhu, Caihong; Dametto, Paolo; Li, Bei; Laferriere, Florent; Polymenidou, Magdalini; Pelczar, Pawel; Reimann, Regina Rose; Schwarz, Petra; Rushing, Elisabeth Jane; Wüthrich, Kurt; Aguzzi, Adriano (2017). Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein. PLoS ONE, 12(2):e0170503.

Frontzek, Karl; Pfammatter, Manuela; Sorce, Silvia; Senatore, Assunta; Schwarz, Petra; Moos, Rita; Frauenknecht, Katrin; Hornemann, Simone; Aguzzi, Adriano (2016). Neurotoxic antibodies against the prion protein do not trigger prion replication. PLoS ONE, 11(9):e0163601.

Küffer, Alexander; Lakkaraju, Asvin K. K; Mogha, Amit; Petersen, Sarah C; Airich, Kristina; Doucerain, Cédric; Marpakwar, Rajlakshmi; Bakirci, Pamela; Senatore, Assunta; Monnard, Arnaud; Schiavi, Carmen; Nuvolone, Mario; Grosshans, Bianka; Hornemann, Simone; Bassilana, Frederic; Monk, Kelly R; Aguzzi, Adriano (2016). The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6. Nature, 536(7617):464-468.

Reimann, Regina R; Sonati, Tiziana; Hornemann, Simone; Herrmann, Uli S; Arand, Michael; Hawke, Simon; Aguzzi, Adriano (2016). Differential toxicity of antibodies to the prion protein. PLoS Pathogens, 12(1):e1005401.

Herrmann, Uli S; Schütz, Anne K; Shirani, Hamid; Huang, Danzhi; Saban, Dino; Nuvolone, Mario; Li, Bei; Ballmer, Boris; Aslund, Andreas; Mason, Jeffrey J; Rushing, Elisabeth J; Budka, Herbert; Nystrom, Sofie; Hammarstrom, Per; Böckmann, Anja; Caflisch, Amedeo; Meier, Beat H; Nilsson, K Peter R; Hornemann, Simone; Aguzzi, Adriano (2015). Structure-based drug design identifies polythiophenes as antiprion compounds. Science Translational Medicine, 7(299):299ra123.

Vanlandewijck, Michael; Lebouvier, Thibaud; Andaloussi Mäe, Maarja; Nahar, Khayrun; Hornemann, Simone; Kenkel, David; Cunha, Sara I; Lennartsson, Johan; Boss, Andreas; Heldin, Carl-Henrik; Keller, Annika; Betsholtz, Christer (2015). Functional characterization of germline mutations in PDGFB and PDGFRB in primary familial brain calcification. PLoS ONE, 10(11):e0143407.

Herrmann, Uli S; Sonati, Tiziana; Falsig, Jeppe; Reimann, Regina R; Dametto, Paolo; O'Connor, Tracy; Li, Bei; Lau, Agnes; Hornemann, Simone; Sorce, Silvia; Wagner, Uli; Sanoudou, Despina; Aguzzi, Adriano (2015). Prion infections and anti-PrP antibodies trigger converging neurotoxic pathways. PLoS Pathogens, 11(2):e1004662.

Franklin, Bernardo S; Bossaller, Lukas; De Nardo, Dominic; Ratter, Jacqueline M; Stutz, Andrea; Engels, Gudrun; Brenker, Christoph; Nordhoff, Mark; Mirandola, Sandra R; Al-Amoudi, Ashraf; Mangan, Matthew S; Zimmer, Sebastian; Monks, Brian G; Fricke, Martin; Schmidt, Reinhold E; Espevik, Terje; Jones, Bernadette; Jarnicki, Andrew G; Hansbro, Philip M; Busto, Patricia; Marshak-Rothstein, Ann; Hornemann, Simone; Aguzzi, Adriano; Kastenmüller, Wolfgang; Latz, Eicke (2014). The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nature Immunology, 15(8):727-737.

Kurt, Timothy D; Bett, Cyrus; Fernández-Borges, Natalia; Joshi-Barr, Shivanjali; Hornemann, Simone; Rülicke, Thomas; Castilla, Joaquín; Wüthrich, Kurt; Aguzzi, Adriano; Sigurdson, Christina J (2014). Prion transmission prevented by modifying the β2-α2 loop structure of host PrPC. Journal of Neuroscience, 34(3):1022-1027.

Christen, Barbara; Damberger, Fred F; Pérez, Daniel R; Hornemann, Simone; Wüthrich, Kurt (2013). Structural plasticity of the cellular prion protein and implications in health and disease. Proceedings of the National Academy of Sciences of the United States of America, 110(21):8549-8554.

Ries, Jonas; Udayar, Vinod; Soragni, Alice; Hornemann, Simone; Nilsson, K Peter R; Riek, Roland; Hock, Christoph; Ewers, Helge; Aguzzi, Adriano A; Rajendran, Lawrence (2013). Superresolution imaging of amyloid fibrils with binding-activated probes. ACS Chemical Neuroscience, 4(7):1057-1061.

Sonati, Tiziana; Reimann, Regina R; Falsig, Jeppe; Baral, Pravas Kumar; O'Connor, Tracy; Hornemann, Simone; Yaganoglu, Sine; Li, Bei; Herrmann, Uli S; Wieland, Barbara; Swayampakula, Mridula; Rahman, Muhammad Hafizur; Das, Dipankar; Kav, Nat; Riek, Roland; Liberski, Pawel P; James, Michael N G; Aguzzi, Adriano (2013). The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature, 501(7465):102-106.

Nystrom, Sofie; Mishra, Rajesh; Hornemann, Simone; Aguzzi, Adriano; Nilsson, K Peter R; Hammarstrom, Per (2012). Multiple substitutions of methionine 129 in human prion protein reveal its importance in the amyloid fibrillation pathway. Journal of Biological Chemistry, 287(31):25975-25984.

Margalith, Ilan; Suter, Carlo; Ballmer, Boris; Schwarz, Petra; Tiberi, Cinzia; Sonati, Tiziana; Falsig, Jeppe; Nystrom, Sofie; Hammarstrom, Per; Aslund, Andreas; Nilsson, K Peter R; Yam, Alice; Whitters, Eric; Hornemann, Simone; Aguzzi, Adriano (2012). Polythiophenes inhibit prion propagation by stabilizing PrP aggregates. Journal of Biological Chemistry, 287(23):18872-18887.

Christen, Barbara; Hornemann, Simone; Damberger, Fred F; Wüthrich, Kurt (2012). Prion Protein mPrP[F175A](121-231): Structure and Stability in Solution. Journal of molecular biology, 423(4):496-502.

Sigurdson, Christina J; Nilsson, K Peter R; Hornemann, Simone; Manco, Giuseppe; Polymenidou, Magdalini; Schwarz, Petra; Leclerc, Mario; Hammarström, Per; Wüthrich, Kurt; Aguzzi, Adriano (2007). Prion strain discrimination using luminescent conjugated polymers. Nature Methods, 4(12):1023-1030.

This list was generated on Fri Oct 19 09:09:33 2018 CEST.