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Higashi, Hideyuki; Maejima, Takashi; Lee, Lang Ho; Yamazaki, Yukiyoshi; Hottiger, Michael O; Singh, Sasha A; Aikawa, Masanori (2019). A study into the ADP-ribosylome of IFN-γ-stimulated THP-1 human macrophage-like cells identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-ribosylation. Journal of Proteome Research, 18(4):1607-1622.

Kunze, Friedrich A; Bauer, Michael; Komuczki, Juliana; Lanzinger, Margit; Gunasekera, Kapila; Hopp, Ann-Katrin; Lehmann, Mareike; Becher, Burkhard; Müller, Anne; Hottiger, Michael O (2019). ARTD1 in myeloid cells controls the IL-12/18–IFN-γ axis in a model of sterile sepsis, chronic bacterial infection, and cancer. Journal of Immunology, 202(5):1406-1416.

Kunze, Friedrich A; Hottiger, Michael O (2019). Regulating Immunity via ADP-Ribosylation: Therapeutic Implications and Beyond. Trends in Immunology, 40(2):159-173.

Lopez-Garcia, Laura A; Demiray, Levent; Ruch-Marder, Sandra; Hopp, Ann-Katrin; Hottiger, Michael O; Helbling, Paul M; Pavlou, Maria P (2018). Validation of extracellular ligand–receptor interactions by Flow-TriCEPS. BMC Research Notes, 11(1):863.

Tugues, Sonia; Amorim, Ana; Spath, Sabine; Martin-Blondel, Guillaume; Schreiner, Bettina; De Feo, Donatella; Lutz, Mirjam; Guscetti, Franco; Apostolova, Petya; Haftmann, Claudia; Hasselblatt, Peter; Núñez, Nicolas G; Hottiger, Michael O; van den Broek, Maries; Manz, Markus G; Zeiser, Robert; Becher, Burkhard (2018). Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF–licensed myeloid cells. Science Translational Medicine, 10(469):eaat8410.

Leslie Pedrioli, Deena M; Leutert, Mario; Bilan, Vera; Nowak, Kathrin; Gunasekera, Kapila; Ferrari, Elena; Imhof, Ralph; Malmström, Lars; Hottiger, Michael O (2018). Comprehensive ADP‐ribosylome analysis identifies tyrosine as an ADP‐ribose acceptor site. EMBO Reports, 19(8):e45310.

Abplanalp, Jeannette; Hopp, Ann-Katrin; Hottiger, Michael O (2018). Mono-ADP-Ribosylhydrolase Assays. In: Chang, Paul. ADP-ribosylation and NAD+ Utilizing Enzymes. Zürich: Springer, 205-213.

Leutert, Mario; Menzel, Stephan; Braren, Rickmer; Rissiek, Björn; Hopp, Ann-Katrin; Nowak, Kathrin; Bisceglie, Lavinia; Gehrig, Peter; Li, Hui; Zolkiewska, Anna; Koch-Nolte, Friedrich; Hottiger, Michael O (2018). Proteomic Characterization of the Heart and Skeletal Muscle Reveals Widespread Arginine ADP-Ribosylation by the ARTC1 Ectoenzyme. Cell Reports, 24(7):1916-1929.e5.

Abplanalp, Jeannette; Leutert, Mario; Frugier, Emilie; Nowak, Kathrin; Feurer, Roxane; Kato, Jiro; Kistemaker, Hans V A; Filippov, Dmitri V; Moss, Joel; Caflisch, Amedeo; Hottiger, Michael O (2017). Proteomic analyses identify ARH3 as a serine mono-ADP-ribosylhydrolase. Nature Communications, 8(1):2055.

Larsen, Sara C; Leutert, Mario; Bilan, Vera; Martello, Rita; Jungmichel, Stephanie; Young, Clifford; Hottiger, Michael O; Nielsen, Michael L (2017). Proteome-wide identification of in vivo ADP-ribose acceptor sites by liquid chromatography–tandem mass spectrometry. In: Tulin, Alexei V. Poly(ADP-Ribose) Polymerase. Switzerland: Springer, 149-162.

Hottiger, Michael O; De Carvalho, Daniel D; Bortoluci, Karina R; et al (2017). Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage. Scientific Reports, 7:41686.

Bisceglie, Lavinia; Bartolomei, Giody; Hottiger, Michael O (2017). ADP-ribose-specific chromatin-affinity purification for investigating genome-wide or locus-specific chromatin ADP-ribosylation. Nature Protocols, 12(9):1951-1961.

Abplanalp, Jeannette; Hottiger, Michael O (2017). Cell fate regulation by chromatin ADP-ribosylation. Seminars in Cell & Developmental Biology, 63:114-122.

Bilan, Vera; Leutert, Mario; Nanni, Paolo; Panse, Christian; Hottiger, Michael O (2017). Combining higher-energy collision dissociation and electron-transfer/higher-energy collision dissociation fragmentation in a product-dependent manner confidently assigns proteomewide adp-ribose acceptor sites. Analytical Chemistry, 89(3):1523-1530.

Rissiek, Björn; Menzel, Stephan; Leutert, Mario; Cordes, Maike; Behr, Sarah; Jank, Larissa; Ludewig, Peter; Gelderblom, Mathias; Rissiek, Anne; Adriouch, Sahil; Haag, Friedrich; Hottiger, Michael O; Koch-Nolte, Friedrich; Magnus, Tim (2017). Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia. Scientific Reports, 7(1):16477.

Leutert, Mario; Bilan, Vera; Gehrig, Peter; Hottiger, Michael O (2017). Identification of ADP-Ribose acceptor sites on in vitro modified proteins by liquid chromatography–tandem mass spectrometry. Methods in Molecular Biology, 1608:137-148.

Bilan, Vera; Selevsek, Nathalie; Kistemaker, Hans A. V; Abplanalp, Jeannette; Feurer, Roxane; Filippov, Dmitri V; Hottiger, Michael O (2017). New quantitative mass spectrometry approaches reveal different ADP-ribosylation phases dependent on the levels of oxidative stress. Molecular & Cellular Proteomics, 16(5):949-958.

Martello, Rita; Leutert, Mario; Jungmichel, Stephanie; Bilan, Vera; Larsen, Sara C; Young, Clifford; Hottiger, Michael O; Nielsen, Michael L (2016). Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue. Nature Communications, 7:12917.

Léger, Karolin; Hopp, Ann-Katrin; Fey, Monika; Hottiger, Michael O (2016). ARTD1 regulates cyclin E expression and consequently cell-cycle re-entry and G1/S progression in T24 bladder carcinoma cells. Cell Cycle, 15(15):2042-2052.

Leutert, Mario; Pedrioli, Deena M Leslie; Hottiger, Michael O (2016). Identification of PARP-specific ADP-ribosylation targets reveals a regulatory function for ADP-ribosylation in transcription elongation. Molecular Cell, 63(2):181-183.

Hofer, Alexandre; Marques, Elia; Kieliger, Nicole; Gatter, Sarah-Kirsten N; Jordi, Sara; Ferrari, Elena; Hofmann, Manuel; Fitzpatrick, Teresa B; Hottiger, Michael O; Jessen, Henning J (2016). Chemoselective Dimerization of Phosphates. Organic Letters, 18(13):3222-3225.

Furrer, Antonia; Hottiger, Michael O; Valaperti, Alan (2016). Absent in Melanoma 2 (AIM2) limits pro-inflammatory cytokine transcription in cardiomyocytes by inhibiting STAT1 phosphorylation. Molecular Immunology, 74:47-58.

Watanabe, Yukihide; Papoutsoglou, Panagiotis; Maturi, Varun; Tsubakihara, Yutaro; Hottiger, Michael O; Heldin, Carl-Henrik; Moustakas, Aristidis (2016). Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation. Journal of Biological Chemistry, 291(24):12706-12723.

Hottiger, Michael O (2016). SnapShot: ADP-Ribosylation Signaling. Molecular Cell, 62(3):472.

Schuster, Sabine; Roessler, Claudia; Meleshin, Marat; Zimmermann, Philipp; Simic, Zeljko; Kambach, Christian; Schiene-Fischer, Cordelia; Steegborn, Clemens; Hottiger, Michael O; Schutkowski, Mike (2016). A continuous sirtuin activity assay without any coupling to enzymatic or chemical reactions. Scientific Reports, 6:22643.

Becker, Annette; Zhang, Peng; Allmann, Lena; Meilinger, Daniela; Bertulat, Bianca; Eck, Daniel; Hofstaetter, Maria; Bartolomei, Giody; Hottiger, Michael O; Schreiber, Valérie; Leonhardt, Heinrich; Cardoso, M. Cristina (2016). Poly(ADP-ribosyl)ation of Methyl CpG Binding Domain Protein 2 Regulates Chromatin Structure. Journal of Biological Chemistry, 291(10):4873-4881.

Bartolomei, Giody; Leutert, Mario; Manzo, Massimiliano; Baubec, Tuncay; Hottiger, Michael O (2016). Analysis of chromatin ADP-Ribosylation at the genome-wide level and at specific loci by ADPr-ChAP. Molecular Cell, 61(3):474-485.

Robaszkiewicz, Agnieszka; Qu, Chao; Wisnik, Ewelina; Ploszaj, Tomasz; Mirsaidi, Ali; Kunze, Friedrich A; Richards, Peter J; Cinelli, Paolo; Mbalaviele, Gabriel; Hottiger, Michael O (2016). ARTD1 regulates osteoclastogenesis and bone homeostasis by dampening NF-κB-dependent transcription of IL-1β. Scientific Reports, 6:21131.

Ma, Bin; Hottiger, Michael O (2016). Crosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during Inflammation. Frontiers in Immunology, 7:378.

Andersson, Anneli; Bluwstein, Andrej; Kumar, Nitin; Teloni, Federico; Traenkle, Jens; Baudis, Michael; Altmeyer, Matthias; Hottiger, Michael O (2016). PKCα and HMGB1 antagonistically control hydrogen peroxide-induced poly-ADP-ribose formation. Nucleic Acids Research, 44(16):7630-7645.

Becker, Annette; Zhang, Peng; Allmann, Lena; Meilinger, Daniela; Bertulat, Bianca; Eck, Daniel; Hofstaetter, Maria; Bartolomei, Giody; Hottiger, Michael O; Schreiber, Valérie; Leonhardt, Heinrich; Cardoso, M. Cristina (2016). Poly(ADP-ribosyl)ation of methyl CpG binding protein 2 regulates chromatin structure. Journal of Biological Chemistry, 291(17):9382.

Rosenthal, Florian; Nanni, Paolo; Barkow-Oesterreicher, Simon; Hottiger, Michael O (2015). Optimization of LTQ-Orbitrap mass spectrometer parameters for the identification of ADP-ribosylation sites. Journal of Proteome Research, 14(9):4072-4079.

Lehmann, Mareike; Pirinen, Eija; Mirsaidi, Ali; Kunze, Friedrich A; Richards, Peter J; Auwerx, Johan; Hottiger, Michael O (2015). ARTD1-induced poly-ADP-ribose formation enhances PPARγ ligand binding and co-factor exchange. Nucleic Acids Research, 43(1):129-142.

Müller-Edenborn, Kamila; Léger, Karolin; Glaus Garzon, Jesus F; Oertli, Carole; Mirsaidi, Ali; Richards, Peter J; Rehrauer, Hubert; Spielmann, Patrick; Hoogewijs, David; Borsig, Lubor; Hottiger, Michael O; Wenger, Roland H (2015). Hypoxia attenuates the proinflammatory response in colon cancer cells by regulating IκB. OncoTarget, 6(24):20288-20301.

Miranda, Melroy X; van Tits, Lambertus J; Lohmann, Christine; Arsiwala, Tasneem; Winnik, Stephan; Tailleux, Anne; Stein, Sokrates; Gomes, Ana P; Suri, Vipin; Ellis, James L; Lutz, Thomas A; Hottiger, Michael O; Sinclair, David A; Auwerx, Johan; Schoonjans, Kristina; Staels, Bart; Lüscher, Thomas F; Matter, Christian M (2015). The Sirt1 activator SRT3025 provides atheroprotection in Apoe-/- mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression. European Heart Journal, 36(1):51-59.

Ryu, Dongryeol; Jo, Young Suk; Lo Sasso, Giuseppe; Stein, Sokrates; Zhang, Hongbo; Perino, Alessia; Lee, Jung Uee; Zeviani, Massimo; Romand, Raymond; Hottiger, Michael O; Schoonjans, Kristina; Auwerx, Johan (2014). A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function. Cell Metabolism, 20(5):856-869.

Léger, Karolin; Bär, Dominik; Savić, Nataša; Santoro, Raffaella; Hottiger, Michael O (2014). ARTD2 activity is stimulated by RNA. Nucleic Acids Research, 42(8):5072-5082.

Dahl, Markus; Maturi, Varun; Lönn, Peter; Papoutsoglou, Panagiotis; Zieba, Agata; Vanlandewijck, Michael; van der Heide, Lars P; Watanabe, Yukihide; Söderberg, Ola; Hottiger, Michael O; Heldin, Carl-Henrik; Moustakas, Aristidis (2014). Fine-tuning of Smad protein function by poly(ADP-ribose) polymerases and poly(ADP-ribose) glycohydrolase during transforming growth factor β signaling. PLoS ONE, 9(8):e103651.

Rosenthal, Florian; Hottiger, Michael O (2014). Identification of ADP-ribosylated peptides and ADP-ribose acceptor sites. Frontiers in Bioscience, 19:1041-1056.

Lo Sasso, Giuseppe; Ryu, Dongryeol; Mouchiroud, Laurent; Fernando, Samodha C; Anderson, Christopher L; Katsyuba, Elena; Piersigilli, Alessandra; Hottiger, Michael O; Schoonjans, Kristina; Auwerx, Johan (2014). Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. PLoS ONE, 9(7):e102495.

Weber, Fabienne A; Bartolomei, Giody; Hottiger, Michael O; Cinelli, Paolo (2013). Artd1/Parp1 regulates reprogramming by transcriptional regulation of Fgf4 via Sox2 ADP-ribosylation. Stem Cells, 31(11):2364-2373.

Kassner, Ingrid; Barandun, Marc; Fey, Monika; Rosenthal, Florian; Hottiger, Michael O (2013). Crosstalk between SET7/9-dependent methylation and ARTD1-mediated ADP-ribosylation of histone H1.4. Epigenetics & Chromatin, 6:1.

Quero, Lilian; Klawitter, Marina; Schmaus, Anja; Rothley, Melanie; Sleeman, Jonathan; Tiaden, André N; Klasen, Juergen; Boos, Norbert; Hottiger, Michael O; Wuertz, Karin; Richards, Peter (2013). Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways. Arthritis Research & Therapy, 15(4):R94.

Rosenthal, Florian; Feijs, Karla L H; Frugier, Emilie; Bonalli, Mario; Forst, Alexandra H; Imhof, Ralph; Winkler, Hans C; Fischer, David; Caflisch, Amedeo; Hassa, Paul O; Lüscher, Bernhard; Hottiger, Michael O (2013). Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases. Nature Structural & Molecular Biology, 20(4):502-507.

Lindgren, Anders E G; Karlberg, Tobias; Thorsell, Ann-Gerd; Hesse, Mareike; Spjut, Sara; Ekblad, Torun; Andersson, C David; Pinto, Ana Filipa; Weigelt, Johan; Hottiger, Michael O; Linusson, Anna; Elofsson, Mikael; Schüler, Herwig (2013). PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3. ACS Chemical Biology, 8(8):1698-1703.

Kraus, W Lee; Hottiger, Michael O (2013). PARP-1 and gene regulation: progress and puzzles. Molecular Aspects of Medicine, 34(6):1109-1123.

Jungmichel, Stephanie; Rosenthal, Florian; Altmeyer, Matthias; Lukas, Jiri; Hottiger, Michael O; Nielsen, Michael L (2013). Proteome-wide identification of poly(ADP-Ribosyl)ation targets in different genotoxic stress responses. Molecular Cell, 52(2):272-285.

Kassner, Ingrid; Andersson, Anneli; Fey, Monika; Tomas, Martin; Ferrando-May, Elisa; Hottiger, Michael O (2013). SET7/9-dependent methylation of ARTD1 at K508 stimulates poly-ADP-ribose formation after oxidative stress. Open Biology, 3(10):120173.

Ziesché, Elisabeth; Kettner-Buhrow, Daniela; Weber, Axel; Wittwer, Tobias; Jurida, Liane; Soelch, Johanna; Müller, Helmut; Newel, Doris; Kronich, Petra; Schneider, Heike; Dittrich-Breiholz, Oliver; Bhaskara, Srividya; Hiebert, Scott W; Hottiger, Michael O; Li, Haiying; Burstein, Ezra; Schmitz, M Lienhard; Kracht, Michael (2013). The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB. Nucleic Acids Research, 41(1):90-109.

Eisele, Petra S; Salatino, Silvia; Sobek, Jens; Hottiger, Michael O; Handschin, Christoph (2013). The peroxisome proliferator-activated receptor γ coactivator 1α/β (PGC-1) coactivators repress the transcriptional activity of NF-κB in skeletal muscle cells. Journal of Biological Chemistry, 288(4):2246-2260.

Erener, Süheda; Mirsaidi, Ali; Hesse, Mareike; Tiaden, André N; Ellingsgaard, Helga; Kostadinova, Radina; Donath, Marc Y; Richards, Peter J; Hottiger, Michael O (2012). ARTD1 deletion causes increased hepatic lipid accumulation in mice fed a high-fat diet and impairs adipocyte function and differentiation. FASEB Journal, 26(6):2631-2638.

Erener, Süheda; Pétrilli, Virginie; Kassner, Ingrid; Minotti, Roberta; Castillo, Rosa; Santoro, Raffaella; Hassa, Paul O; Tschopp, Jürg; Hottiger, Michael O (2012). Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-κB target genes. Molecular Cell, 46(2):200-211.

Guetg, Claudio; Scheifele, Fabian; Rosenthal, Florian; Hottiger, Michael O; Santoro, Raffaella (2012). Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA. Molecular Cell, 45(6):790-800.

Erener, Süheda; Hesse, Mareike; Kostadinova, Radina; Hottiger, Michael O (2012). Poly(ADP-ribose)polymerase-1 (PARP1) controls adipogenic gene expression and adipocyte function. Molecular Endocrinology, 26(1):79-86.

von Lukowicz, T; Hassa, P O; Lohmann, C; Borén, J; Braunersreuther, V; Mach, F; Odermatt, B; Gersbach, M; Camici, G G; Stähli, B E; Tanner, F C; Hottiger, Michael O; Lüscher, T F; Matter, C M (2008). PARP1 is required for adhesion molecule expression in atherogenesis. Cardiovascular Research, 78(1):158-166.

Kamau, S W; Hassa, P O; Steitz, B; Petri-Fink, A; Hofmann, H; Hofmann-Amtenbrink, M; von Rechenberg, Brigitte; Hottiger, Michael O (2006). Enhancement of the efficiency of non-viral gene delivery by application of pulsed magnetic field. Nucleic Acids Research, 34(5):e40.

Cramer, Mirjam; Nagy, Ivana; Murphy, Brian J; Gassmann, Max; Hottiger, Michael O; Georgiev, Oleg; Schaffner, Walter (2006). NF-κB contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells. Biological Chemistry, 387(1):113.

Cramer, Mirjam; Nagy, Ivana; Murphy, Brian J; Gassmann, Max; Hottiger, Michael O; Georgiev, Oleg; Schaffner, Walter (2005). NF-kappaB contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells. Biological Chemistry, 386(9):865-872.

Toueille, M; El-Andaloussi, N; Frouin, I; Freire, R; Funk, D; Shevelev, I V; Friedrich-Heineken, E; Villani, G; Hottiger, Michael O; Hübscher, U (2004). The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair. Nucleic Acids Research, 32(11):3316-3324.

This list was generated on Mon Jun 24 11:50:20 2019 CEST.