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Penton, David; Moser, Sandra; Wengi, Agnieszka; Czogalla, Jan; Rosenbaek, Lena Lindtoft; Rigendinger, Fritz; Faresse, Nourdine; Martins, Joana R; Fenton, Robert A; Loffing-Cueni, Dominique; Loffing, Johannes (2019). Protein Phosphatase 1 Inhibitor–1 Mediates the cAMP-Dependent Stimulation of the Renal NaCl Cotransporter. Journal of the American Society of Nephrology (JASN), 30(5):737-750.

Cianciolo Cosentino, Chiara; Berto, Alessandro; Pelletier, Stéphane; Hari, Michelle; Loffing, Johannes; Neuhauss, Stephan C F; Doye, Valérie (2019). Moderate Nucleoporin 133 deficiency leads to glomerular damage in zebrafish. Scientific Reports, 9:4750.

Eckhard, Andreas H; Zhu, MengYu; O’Malley, Jennifer T; Williams, Gordon H; Loffing, Johannes; Rauch, Steven D; Nadol, Joe B; Liberman, M Charles; Adams, Joe C (2019). Inner ear pathologies impair sodium-regulated ion transport in Meniere’s disease. Acta Neuropathologica, 137(2):343-357.

Craigie, Eilidh; Menzies, R I; Larsen, C K; Jacquillet, G; Carrel, Monique; Wildmann, S S; Loffing, Johannes; Shirley, D G; Bailey, M A; Unwin, R J (2018). The renal and blood pressure response to low sodium diet in P2X4 receptor knockout mice. Physiological Reports, 6(20):e13899.

Tokonami, Natsuko; Takata, Tomoaki; Beyeler, Jan; Ehrbar, Iris; Yoshifuji, Ayumi; Christensen, Erik I; Loffing, Johannes; Devuyst, Olivier; Olinger, Eric G (2018). Uromodulin is expressed in the distal convoluted tubule, where it is critical for regulation of the sodium chloride cotransporter NCC. Kidney International, 94(4):701-715.

Murillo-de-Ozores, Adrián Rafael; Rodríguez-Gama, Alejandro; Bazúa-Valenti, Silvana; Leyva-Ríos, Karla; Vázquez, Norma; Pacheco-Álvarez, Diana; De La Rosa-Velázquez, Inti A; Wengi, Agnieszka; Stone, Kathryn L; Zhang, Junhui; Loffing, Johannes; Lifton, Richard P; Yang, Chao-Ling; Ellison, David H; Gamba, Gerardo; Castañeda-Bueno, Maria (2018). C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity. Journal of Biological Chemistry, 293(31):12209-12221.

Ravarotto, Verdiana; Loffing, Johannes; Loffing-Cueni, Dominique; Heidemeyer, Michèle; Pagnin, Elisa; Calò, Lorenzo A; Rossi, Gian Paolo (2018). Gitelman’s Syndrome: characterization of a novel c.1181G>A point mutation and functional classification of the known mutations. Hypertension Research, 41(8):578-588.

Boscardin, Emilie; Perrier, Romain; Sergi, Chloé; Maillard, Marc P; Loffing, Johannes; Loffing-Cueni, Dominique; Koesters, Robert; Rossier, Bernard C; Hummler, Edith (2018). Plasma Potassium Determines NCC Abundance in Adult Kidney-SpecificγENaC Knockout. Journal of the American Society of Nephrology (JASN), 29(3):977-990.

Udwan, Khalil; Abed, Ahmed; Roth, Isabelle; Dizin, Eva; Maillard, Marc; Bettoni, Carla; Loffing, Johannes; Wagner, Carsten A; Edwards, Aurélie; Feraille, Eric (2017). Dietary sodium induces a redistribution of the tubular metabolic workload. Journal of Physiology, 595(22):6905-6922.

Nagarajan, Shunmugam; Vohra, Twinkle; Loffing, Johannes; Faresse, Nourdine (2017). Protein Phosphatase 1α enhances renal aldosterone signaling via mineralocorticoid receptor stabilization. Molecular and Cellular Endocrinology, 450:74-82.

Sugano, Yuya; Cianciolo Cosentino, Chiara; Loffing-Cueni, Dominique; Neuhauss, Stephan C. F; Loffing, Johannes (2017). Comparative transcriptomic analysis identifies evolutionarily conserved gene products in the vertebrate renal distal convoluted tubule. Pflügers Archiv : European Journal of Physiology, 469(7-8):859-867.

Boscardin, Emilie; Perrier, Romain; Sergi, Chloé; Maillard, Marc; Loffing, Johannes; Loffing-Cueni, Dominique; Koesters, Robert; Rossier, Bernard Claude; Hummler, Edith (2017). Severe hyperkalemia is rescued by low-potassium diet in renal βENaC-deficient mice. Pflügers Archiv : European Journal of Physiology, 469(10):1387-1399.

Tokonami, Natsuko; Cheval, Lydie; Monnay, Isabelle; Meurice, Guillaume; Loffing, Johannes; Feraille, Eric; Houillier, Pascal (2017). Endothelin-1 mediates natriuresis but not polyuria during vitamin D-induced acute hypercalcaemia. Journal of Physiology, 595(8):2535-2550.

Ueda, Kohei; Nishimoto, Mitsuhiro; Hirohama, Daigoro; Ayuzawa, Nobuhiro; Kawarazaki, Wakako; Watanabe, Atsushi; Shimosawa, Tatsuo; Loffing, Johannes; Zhang, Ming-Zhi; Marumo, Takeshi; Fujita, Toshiro (2017). Renal dysfunction induced by kidney-specific gene deletion of Hsd11b2 as a primary cause of salt-dependent hypertension. Hypertension, 70(1):111-118.

Czogalla, Jan; Schweda, Frank; Loffing, Johannes (2016). The mouse isolated perfused kidney technique. Journal of Visualized Experiments (Jove), (117):e54712.

Ishizawa, Kenichi; Xu, Ning; Loffing, Johannes; Lifton, Richard P; Fujita, Toshiro; Uchida, Shunya; Shibata, Shigeru (2016). Potassium depletion stimulates Na-Cl cotransporter via phosphorylation and inactivation of the ubiquitin ligase Kelch-like 3. Biochemical and Biophysical Research Communications, 480(4):745-751.

Penton, David; Czogalla, Jan; Wengi, Agnieszka; Himmerkus, Nina; Loffing-Cueni, Dominique; Carrel, Monique; Rajaram, Renuga Devi; Staub, Olivier; Bleich, Markus; Schweda, Frank; Loffing, Johannes (2016). Extracellular K$^+$ rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl$^-$-dependent and independent mechanisms. Journal of Physiology, 594(21):6319-6331.

Al-Qusairi, Lama; Basquin, Denis; Roy, Ankita; Stifanelli, Matteo; Rajaram, Renuga Devi; Debonneville, Anne; Nita, Izabela; Maillard, Marc; Loffing, Johannes; Subramanya, Arohan R; Staub, Olivier (2016). Renal tubular SGK1 deficiency causes impaired K+excretion via loss of regulation of NEDD4-2/WNK1 and ENaC. American Journal of Physiology: Renal Physiology, 311(2):330-342.

Janas, Sylvie; Seghers, François; Schakman, Olivier; Alsady, Mohammad; Deen, Peter; Vriens, Joris; Tissir, Fadel; Nilius, Bernd; Loffing, Johannes; Gailly, Philippe; Devuyst, Olivier (2016). TRPV4 is associated with central rather than nephrogenic osmoregulation. Pflügers Archiv : European Journal of Physiology, 468(9):1595-1607.

Loffing, Johannes (2016). Der thiazid-sensitive NaCl-Kotransporter. Nieren- und Hochdruckkrankheiten:247-251.

Segerer, Stephan; Sugano, Yuya; Lindenmeyer, Maja T; Auberger, Ines; Ziegler, Urs; Cohen, Clemens D; Neuhauss, Stephan C F; Loffing, Johannes (2016). The Authors Reply. Kidney International, 89(5):1161-1162.

Czogalla, Jan; Vohra, Twinkle; Penton, David; Kirschmann, Moritz; Craigie, Eilidh; Loffing, Johannes (2016). The mineralocorticoid receptor (MR) regulates ENaC but not NCC in mice with random MR deletion. Pflügers Archiv : European Journal of Physiology, 468(5):849-858.

Canonica, Jérémie; Sergi, Chloé; Maillard, Marc; Klusonova, Petra; Odermatt, Alex; Koesters, Robert; Loffing-Cueni, Dominique; Loffing, Johannes; Rossier, Bernard; Frateschi, Simona; Hummler, Edith (2016). Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype. Pflügers Archiv : European Journal of Physiology, 468(5):895-908.

de Groot, Theun; Sinke, Anne P; Kortenoeven, Marleen L A; Alsady, Mohammad; Baumgarten, Ruben; Devuyst, Olivier; Loffing, Johannes; Wetzels, Jack F; Deen, Peter M T (2016). Acetazolamide Attenuates Lithium-Induced Nephrogenic Diabetes Insipidus. Journal of the American Society of Nephrology (JASN), 27(7):2082-2091.

Mordasini, David; Loffing-Cueni, Dominique; Loffing, Johannes; Beatrice, Rohrbach; Maillard, Marc P; Hummler, Edith; Burnier, Michel; Escher, Geneviève; Vogt, Bruno (2015). ENaC activity in collecting ducts modulates NCC in cirrhotic mice. Pflügers Archiv : European Journal of Physiology, 467(12):2529-2539.

Di Chiara, Marianna; Glaudemans, Bob; Loffing-Cueni, Dominique; Odermatt, Alex; Al-Hasani, Hadi; Devuyst, Olivier; Faresse, Nourdine; Loffing, Johannes (2015). Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney. American Journal of Physiology. Renal, Fluid and Electrolyte Physiology, 309(9):F779-F790.

Sugano, Yuya; Lindenmeyer, Maja T; Auberger, Ines; Ziegler, Urs; Segerer, Stephan; Cohen, Clemens D; Neuhauss, Stephan C F; Loffing, Johannes (2015). The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier. Kidney International, 88(5):1047-1056.

Hoorn, Ewout J; Loffing, Johannes; Ellison, David H (2015). An integrated view of potassium homeostasis. New England Journal of Medicine, 373(18):1786.

Chadt, Alexandra; Immisch, Anja; de Wendt, Christian; Springer, Christian; Zhou, Zhou; Stermann, Torben; Holman, Geoffrey D; Loffing-Cueni, Dominique; Loffing, Johannes; Joost, Hans-Georg; Al-Hasani, Hadi (2015). Deletion of both Rab-GTPase-activating proteins TBC14KO and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport. Diabetes, 64(4):1492.

Alves, Daiane S; Thulin, Gunilla; Loffing, Johannes; Kashgarian, Michael; Caplan, Michael J (2015). Akt substrate of 160 kD regulates Na+,K+-ATPase trafficking in response to energy depletion and renal ischemia. Journal of the American Society of Nephrology (JASN), 26(11):2765-2776.

Penton, David; Czogalla, Jan; Loffing, Johannes (2015). Dietary potassium and the renal control of salt balance and blood pressure. Pflügers Archiv : European Journal of Physiology, 467(3):513-530.

Chadt, Alexandra; Immisch, Anja; de Wendt, Christian; Springer, Christian; Zhou, Zhou; Stermann, Torben; Holman, Geoffrey D; Loffing-Cueni, Dominique; Loffing, Johannes; Joost, Hans-Georg; Al-Hasani, Hadi (2015). Deletion of Both Rab-GTPase-Activating Proteins TBC1D1 and TBC1D4 in Mice Eliminates Insulin- and AICAR-Stimulated Glucose Transport. Diabetes, 64(3):746-759.

Todkar, Abhijeet; Picard, Nicolas; Loffing-Cueni, Dominique; Sorensen, Mads V; Mihailova, Marija; Nesterov, Viatcheslav; Makhanova, Natalia; Korbmacher, Christoph; Wagner, Carsten A; Loffing, Johannes (2015). Mechanisms of renal control of potassium homeostasis in complete aldosterone deficiency. Journal of the American Society of Nephrology (JASN), 26(2):425-438.

Demoulin, Nathalie; Aydin, Selda; Cosyns, Jean-Pierre; Dahan, Karin; Cornet, Georges; Auberger, Ines; Loffing, Johannes; Devuyst, Olivier (2014). Gitelman syndrome and glomerular proteinuria: a link between loss of sodium-chloride cotransporter and podocyte dysfunction? Nephrology, Dialysis, Transplantation, 29 Suppl:iv117-iv120.

Terker, Andrew S; Yang, Chao-Ling; McCormick, James A; Meermeier, Nicholas P; Rogers, Shaunessy L; Grossmann, Solveig; Trompf, Katja; Delpire, Eric; Loffing, Johannes; Ellison, David H (2014). Sympathetic stimulation of thiazide-sensitive sodium chloride cotransport in the generation of salt-sensitive hypertension. Hypertension, 64(1):178-184.

Olden, Matthias; Corre, Tanguy; Hayward, Caroline; Toniolo, Daniela; Ulivi, Sheila; Gasparini, Paolo; Pistis, Giorgio; Hwang, Shih-Jen; Bergmann, Sven; Campbell, Harry; Cocca, Massimiliano; Gandin, Ilaria; Girotto, Giorgia; Glaudemans, Bob; Hastie, Nicholas D; Loffing, Johannes; Polasek, Ozren; Rampoldi, Luca; Rudan, Igor; Sala, Cinzia; Traglia, Michela; Vollenweider, Peter; Vuckovic, Dragana; Youhanna, Sonia; Weber, Julien; Wright, Alan F; Kutalik, Zoltán; Bochud, Murielle; Fox, Caroline S; Devuyst, Olivier (2014). Common Variants in UMOD Associate with Urinary Uromodulin Levels: A Meta-Analysis. Journal of the American Society of Nephrology (JASN), 25(8):1869-1882.

Sinke, Anne P; Kortenoeven, Marleen L A; de Groot, Theun; Baumgarten, Ruben; Devuyst, Olivier; Wetzels, Jack F M; Loffing, Johannes; Deen, Peter M T (2014). Hydrochorothiazide attenuates lithium-induced Nephrogenic Diabetes Insipidus independently of the sodium-chloride co-transporter. American Journal of Physiology. Renal, Fluid and Electrolyte Physiology, 306(5):F525-33.

Picard, Nicolas; Trompf, Katja; Yang, Chao-Ling; Miller, R Lance; Carrel, Monique; Loffing-Cueni, Dominique; Fenton, Robert A; Ellison, David H; Loffing, Johannes (2014). Protein phosphatase 1 inhibitor-1 deficiency reduces phosphorylation of renal NaCl cotransporter and causes arterial hypotension. Journal of the American Society of Nephrology (JASN), 25(3):511-522.

Moes, Arthur D; van der Lubbe, Nils; Zietse, Robert; Loffing, Johannes; Hoorn, Ewout J (2014). The sodium chloride cotransporter SLC12A3: new roles in sodium, potassium, and blood pressure regulation. Pflügers Archiv : European Journal of Physiology, 466(1):107-118.

Ronzaud, Caroline; Loffing-Cueni, Dominique; Hausel, Pierrette; Debonneville, Anne; Malsure, Sumedha Ram; Fowler-Jaeger, Nicole; Boase, Natasha A; Perrier, Romain; Maillard, Marc; Yang, Baoli; Stokes, John B; Koesters, Robert; Kumar, Sharad; Hummler, Edith; Loffing, Johannes; Staub, Olivier (2013). Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension. Journal of Clinical Investigation:657-665.

Trudu, Matteo; Janas, Sylvie; Lanzani, Chiara; Debaix, Huguette; Schaeffer, Céline; Ikehata, Masami; Citterio, Lorena; Demaretz, Sylvie; Trevisani, Francesco; Ristagno, Giuseppe; Glaudemans, Bob; Laghmani, Kamel; Dell'antonio, Giacomo; SKIPOGH team; Loffing, Johannes; Rastaldi, Maria P; Manunta, Paolo; Devuyst, Olivier; Rampoldi, Luca (2013). Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression. Nature Medicine, 19(12):1655-1660.

Pouly, Daniel; Debonneville, Anne; Ruffieux-Daidié, Dorothée; Maillard, Marc; Abriel, Hugues; Loffing, Johannes; Staub, Olivier (2013). Mice carrying ubiquitin-specific protease 2 (Usp2) gene inactivation maintain normal sodium balance and blood pressure. American Journal of Physiology. Renal, Fluid and Electrolyte Physiology, 305(1):F21-30.

Sorensen, Mads V; Grossmann, Solveig; Roesinger, Marian; Gresko, Nikolay; Todkar, Abhijeet P; Barmettler, Gery; Ziegler, Urs; Odermatt, Alex; Loffing-Cueni, Dominique; Loffing, Johannes (2013). Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in mice. Kidney International, 83(5):811-824.

Nesterov, Viatcheslav; Dahlmann, Anke; Krueger, Bettina; Bertog, Marko; Loffing, Johannes; Korbmacher, Christoph (2012). Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron. American Journal of Physiology. Renal Physiology:F1289-F1299.

Markadieu, Nicolas; San-Cristobal, Pedro; Nair, Anil V; Verkaart, Sjoerd; Lenssen, Ellen; Tudpor, Kukiat; van Zeeland, Femke; Loffing, Johannes; Bindels, René J M (2012). A primary culture of distal convoluted tubules expressing functional thiazide-sensitive NaCl transport. American Journal of Physiology. Renal Physiology:F886-F892.

Todkar, Abhijeet; Di Chiara, Marianna; Loffing-Cueni, Dominique; Bettoni, Carla; Mohaupt, Markus; Loffing, Johannes; Wagner, Carsten A (2012). Aldosterone deficiency adversely affects pregnancy outcome in mice. Pflügers Archiv: European Journal of Physiology (Pflugers Archiv), 464(4):331-343.

Lier, Natascha; Gresko, Nikolay; Di Chiara, Marianna; Loffing-Cueni, Dominique; Loffing, Johannes (2012). Immunofluorescent localization of the Rab-GAP protein TBC1D4 (AS160) in mouse kidney. Histochemistry and Cell Biology, 138(1):101-112.

Braun, Matthias; Young, James; Reiner, Cäcilia S; Poster, Diane; Krauer, Fabienne; Kistler, Andreas D; Kristanto, Paulus; Wang, Xueqi; Liu, Yang; Loffing, Johannes; Andreisek, Gustav; von Eckardstein, Arnold; Senn, Oliver; Wüthrich, Rudolf P; Serra, Andreas L (2012). Low-Dose Oral Sirolimus and the Risk of Menstrual-Cycle Disturbances and Ovarian Cysts: Analysis of the Randomized Controlled SUISSE ADPKD Trial. PLoS ONE, 7(10):e45868.

Olinger, Eric; Schwaller, Beat; Loffing, Johannes; Gailly, Philippe; Devuyst, Olivier (2012). Parvalbumin: calcium and magnesium buffering in the distal nephron. Nephrology, Dialysis, Transplantation, 27(11):3988-3994.

Picard, Nicolas; Van Abel, Monique; Campone, Christelle; Seiler, Michelle; Bloch-Faure, May; Hoenderop, Joost G J; Loffing, Johannes; Meneton, Pierre; Bindels, René J M; Paillard, Michel; Alhenc-Gelas, François; Houillier, Pascal (2005). Tissue kallikrein-deficient mice display a defect in renal tubular calcium absorption. Journal of the American Society of Nephrology (JASN), 16(12):3602-10.

Yu, Zhenrong; Serra, Andreas; Sauter, Daniel; Loffing, Johannes; Ackermann, Daniel; Frey, Felix J; Frey, Brigitte M; Vogt, Bruno (2005). Sodium retention in rats with liver cirrhosis is associated with increased renal abundance of NaCl cotransporter (NCC). Nephrology, Dialysis, Transplantation, 20(9):1833-1841.

Le Hir, Michel; Hegyi, Ivan; Cueni-Loffing, Dominique; Loffing, Johannes; Kaissling, Brigitte (2005). Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys. Histochemistry and Cell Biology, 123(4-5):335-346.

This list was generated on Mon Jun 24 21:50:12 2019 CEST.