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Menigatti, M; Staiano, T; Manser, C N; Bauerfeind, P; Komljenovic, A; Robinson, M; Jiricny, J; Buffoli, F; Marra, G (2013). Epigenetic silencing of monoallelically methylated miRNA loci in precancerous colorectal lesions. Oncogenesis, 2:e56.

von Bueren, A O; Bacolod, M D; Hagel, C; Heinimann, K; Fedier, A; Kordes, U; Pietsch, T; Koster, J; Grotzer, M A; Friedman, H S; Marra, G; Kool, M; Rutkowski, S (2012). Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours. British Journal of Cancer, 107(8):1399-1408.

Vasovcak, P; Krepelova, A; Menigatti, M; Puchmajerova, A; Skapa, P; Augustinakova, A; Amann, G; Wernstedt, A; Jiricny, J; Marra, G; Wimmer, K (2012). Unique mutational profile associated with a loss of TDG expression in the rectal cancer of a patient with a constitutional PMS2 deficiency. DNA Repair, 11(7):616-623.

Pocsfalvi, G; Votta, G; De Vincenzo, A; Fiume, I; Raj, D A A; Marra, G; Stoppelli, M P; Iaccarino, I (2011). Analysis of secretome changes uncovers an autocrine/paracrine component in the ability of c -Myc to modulate cell proliferation and motility. Journal of Proteome Research, 10(12):5326-5337.

Kovac, M; Laczko, E; Haider, R; Jiricny, J; Mueller, H; Heinimann, K; Marra, G (2011). Familial colorectal cancer: eleven years of data from a registry program in Switzerland. Familial Cancer, 10(3):605-616.

Cattaneo, E; Baudis, M; Buffoli, F; Bianco, M A; Zorzi, F; Marra, G (2011). Pathways and crossroads to colorectal cancer. In: Fitzgerald, R C. Pre-Invasive Disease: Pathogenesis and Clinical Management. New York: Springer, 369-394.

Cattaneo, E; Laczko, E; Buffoli, F; Zorzi, F; Bianco, M A; Menigatti, M; Bartosova, Z; Haider, R; Helmchen, B; Sabates-Bellver, J; Tiwari, A; Jiricny, J; Marra, G (2011). Preinvasive colorectal lesion transcriptomes correlate with endoscopic morphology (polypoid vs. nonpolypoid). EMBO Molecular Medicine, 3(6):334-347.

Gillessen, S; Templeton, A; Marra, G; Kuo, Y F; Valtorta, E; Shahinian, V B (2010). Risk of colorectal cancer in men on long-term androgen deprivation therapy for prostate cancer. Journal of the National Cancer Institute, 102(23):1760-1770.

Menigatti, M; Truninger, K; Gebbers, J O; Marbet, U; Marra, G; Schär, P (2009). Normal colorectal mucosa exhibits sex- and segment-specific susceptibility to DNA methylation at the hMLH1 and MGMT promoters. Oncogene, 28(6):899-909.

Siehler, S Y; Schrauder, M; Gerischer, U; Cantor, S; Marra, G; Wiesmüller, L (2009). Human MutL-complexes monitor homologous recombination independently of mismatch repair. DNA Repair, 8(2):242-252.

Templeton, A; Marra, G; Valtorta, E; Heinimann, K; Müller, H; Köberle, D; Gillessen, S (2009). Concordant colon tumors in monozygotic twins previously treated for prostate cancer. Familial Cancer, 8(2):167-171.

Menigatti, M; Cattaneo, E; Sabates-Bellver, J; Ilinsky, V V; Went, P; Buffoli, F; Marquez, V E; Jiricny, J; Marra, G (2009). The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis. Molecular Cancer Therapeutics, 8:124.

Marra, G. Understanding tumorigenesis of the large intestine: The cornerstone of effective cancer prevention strategies. 2009, University of Zurich, Faculty of Science.

Haugen, A C; Goel, A; Yamada, K; Marra, G; Nguyen, T P; Nagasaka, T; Kanazawa, S; Koike, J; Kikuchi, Y; Zhong, X; Arita, M; Shibuya, K; Oshimura, M; Hemmi, H; Boland, C R; Koi, M (2008). Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer. Cancer Research, 68(20):8465-8472.

Bujalkova, M; Zavodna, K; Krivulcik, T; Ilencikova, D; Wolf, B; Kovac, M; Karner-Hanusch, J; Heinimann, K; Marra, G; Jiricny, J; Bartosova, Z (2008). Multiplex SNaPshot genotyping for detecting loss of heterozygosity in the mismatch-repair genes MLH1 and MSH2 in microsatellite-unstable tumors. Clinical Chemistry, 54:1844-1854.

Cannavo, E; Gerrits, B; Marra, G; Schlapbach, R; Jiricny, J (2007). Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS. Journal of Biological Chemistry, 282(5):2976-86.

Stella, A; Surdo, N C; Lastella, P; Barana, D; Oliani, C; Tibiletti, M G; Viel, A; Natale, C; Piepoli, A; Marra, G; Guanti, G (2007). Germline novel MSH2 deletions and a founder MSH2 deletion associated with anticipation effects in HNPCC. Clinical Genetics, 71(2):130-139.

Menigatti, M; Pedroni, M; Verrone, A M; Borghi, F; Scarselli, A; Benatti, P; Losi, L; Di Gregorio, C; Schär, P; Marra, G; Ponz de Leon, M; Roncucci, L (2007). O6-methylguanine-DNA methyltransferase promoter hypermethylation in colorectal carcinogenesis. Oncology Reports, 17(6):1421-1427.

Weiss, M B; Vitolo, M I; Baerenfaller, K; Marra, G; Park, B H; Bachman, K E (2007). Persistent mismatch repair deficiency following targeted correction of hMLH1. Cancer Gene Therapy, 14(1):98-104.

Van der Flier, L G; Sabates-Bellver, J; Oving, I; Haegebarth, A; De Palo, M; Anti, M; Van Gijn, M E; Suijkerbuijk, S; Van de Wetering, M; Marra, G; Clevers, H (2007). The Intestinal Wnt/TCF Signature. Gastroenterology, 132(2):628-632.

Sabates-Bellver, J; Van der Flier, L G; de Palo, M; Cattaneo, E; Maake, C; Rehrauer, H; Laczko, E; Kurowski, M A; Bujnicki, J M; Menigatti, M; Luz, J; Ranalli, T V; Gomes, V; Pastorelli, A; Faggiani, R; Anti, M; Jiricny, J; Clevers, H; Marra, G (2007). Transcriptome profile of human colorectal adenomas. Molecular Cancer Research, 5(12):1263-1275.

Plasilova, M; Zhang, J; Okhowat, R; Marra, G; Mettler, M; Mueller, H; Heinimann, K (2006). A de novo MLH1 germ line mutation in a 31-year-old colorectal cancer patient. Genes, Chromosomes & Cancer, 45(12):1106-1110.

Alvino, E; Castiglia, D; Caporali, S; Pepponi, R; Caporaso, P; Lacal, P M; Marra, G; Fischer, F; Zambruno, G; Bonmassar, E; Jiricny, J; D'Atri, S (2006). A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system. International Journal of Oncology, 29(4):785-797.

Zhang, J; Lindroos, A; Ollila, S; Russell, A; Marra, G; Mueller, H; Peltomaki, P; Plasilova, M; Heinimann, K (2006). Gene conversion is a frequent mechanism of inactivation of the wild-type allele in cancers from MLH1/MSH2 deletion carriers. Cancer Research, 66(2):659-664.

Zavodna, K; Bujalkova, M; Krivulcik, T; Alemayehu, A; Skorvaga, M; Marra, G; Fridrichova, I; Jiricny, J; Bartosova, Z (2006). Novel and recurrent germline alterations in the MLH1 and MSH2 genes identified in hereditary nonpolyposis colorectal cancer patients in Slovakia. Neoplasma, 53(4):269-276.

Szadkowski, M; Iaccarino, I; Heinimann, K; Marra, G; Jiricny, J (2005). Characterization of the mismatch repair defect in the human lymphoblastoid MT1 cells. Cancer Research, 65(11):4525-4529.

Marra, G; Jiricny, J (2005). DNA mismatch repair and colon cancer. In: Nigg, E A. Genome Instability in Cancer Development. Netherland: Springer, 85-123.

di Pietro, M; Sabates-Bellver, J; Menigatti, M; Bannwart, F; Schnider, A; Russell, A; Truninger, K; Jiricny, J; Marra, G (2005). Defective DNA mismatch repair determines a characteristic transcriptional profile in proximal colon cancers. Gastroenterology, 129(3):1047-1059.

Cannavo, E; Marra, G; Sabates-Bellver, J; Menigatti, M; Lipkin, S M; Fischer, F; Cejka, P; Jiricny, J (2005). Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair. Cancer Research, 65(23):10759-10766.

Truninger, K; Menigatti, M; Luz, J; Russell, A; Haider, R; Gebbers, J-O; Bannwart, F; Yurtsever, H; Neuweiler, J; Riehle, H-M; Cattaruzza, M S; Heinimann, K; Schär, P; Jiricny, J; Marra, G (2005). Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer. Gastroenterology, 128(5):1160-1171.

Klasen, M; Spillmann, F; Marra, G; Cejka, P; Wabl, M (2005). Somatic hypermutation and mismatch repair in non-B cells. European Journal of Immunology, 35(7):2222-2229.

Cejka, P; Stojic, L; Marra, G; Jiricny, J (2004). Is mismatch repair really required for ionizing radiation-induced DNA damage signaling? Nature Genetics, 36(5):432-3; author reply 434.

Plaschke, J; Krüger, S; Jeske, B; Theissig, F; Kreuz, F R; Pistorius, S; Saeger, H D; Iaccarino, I; Marra, G; Schackert, H K (2004). Loss of MSH3 protein expression is frequent in MLH1-deficient colorectal cancer and is associated with disease progression. Cancer Research, 64(3):864-870.

Stojic, L; Mojas, N; Cejka, P; Di Pietro, M; Ferrari, S; Marra, G; Jiricny, J (2004). Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase. Genes and Development, 18(11):1331-1344.

Muheim-Lenz, R; Buterin, T; Marra, G; Naegeli, H (2004). Short-patch correction of C/C mismatches in human cells. Nucleic Acids Research, 32(22):6696-6705.

Castiglia, D; Pagani, E; Alvino, E; Vernole, P; Marra, G; Cannavò, E; Jiricny, J; Zambruno, G; D'Atri, S (2003). Biallelic somatic inactivation of the mismatch repair gene MLH1 in a primary skin melanoma. Genes, Chromosomes & Cancer, 37(2):165-175.

Jiricny, J; Marra, G (2003). DNA repair defects in colon cancer. Current Opinion in Genetics & Development, 13(1):61-69.

Cejka, P; Marra, G; Hemmerle, C; Cannavó, E; Storchova, Z; Jiricny, J (2003). Differential killing of mismatch repair-deficient and -proficient cells: towards the therapy of tumors with microsatellite instability. Cancer Research, 63(23):8113-8117.

Cejka, P; Stojic, L; Mojas, N; Russell, A F; Heinimann, K; Cannavó, E; di Pietro, M; Marra, G; Jiricny, J (2003). Methylation-induced G(2)/M arrest requires a full complement of the mismatch repair protein hMLH1. EMBO Journal, 22(9):2245-2254.

di Pietro, M; Marra, G; Cejka, P; Stojic, L; Menigatti, M; Cattaruzza, M S; Jiricny, J (2003). Mismatch repair-dependent transcriptome changes in human cells treated with the methylating agent N-methyl-n'-nitro-N-nitrosoguanidine. Cancer Research, 63(23):8158-8166.

Marra, G; Jiricny, J (2003). Multiple colorectal adenomas--is their number up? New England Journal of Medicine, 348(9):845-847.

Bartosova, Z; Fridrichova, I; Bujalkova, M; Wolf, B; Ilencikova, D; Krizan, P; Hlavcak, P; Palaj, J; Lukac, L; Lukacova, M; Böör, A; Haider, R; Jiricny, J; Nyström-Lahti, M; Marra, G (2003). Novel MLH1 and MSH2 germline mutations in the first HNPCC families identified in Slovakia. Human Mutation, 21(4):449.

Pepponi, R; Marra, G; Fuggetta, M P; Falcinelli, S; Pagani, E; Bonmassar, E; Jiricny, J; D'Atri, S (2003). The effect of O6-alkylguanine-DNA alkyltransferase and mismatch repair activities on the sensitivity of human melanoma cells to temozolomide, 1,3-bis(2-chloroethyl)1-nitrosourea, and cisplatin. Journal of Pharmacology and Experimental Therapeutics, 304(2):661-668.

Klingler, H; Hemmerle, C; Bannwart, F; Haider, R; Cattaruzza, M S; Marra, G (2002). Expression of the hMSH6 mismatch-repair protein in colon cancer and HeLa cells. Swiss Medical Weekly, 132(5-6):57-63.

Nyström-Lahti, M; Perrera, C; Räschle, M; Panyushkina-Seiler, E; Marra, G; Curci, A; Quaresima, B; Costanzo, F; D'Urso, M; Venuta, S; Jiricny, J (2002). Functional analysis of MLH1 mutations linked to hereditary nonpolyposis colon cancer. Genes, Chromosomes & Cancer, 33(2):160-167.

Trojan, J; Zeuzem, S; Randolph, A; Hemmerle, C; Brieger, A; Raedle, J; Plotz, G; Jiricny, J; Marra, G (2002). Functional analysis of hMLH1 variants and HNPCC-related mutations using a human expression system. Gastroenterology, 122(1):211-219.

Alvino, E; Marra, G; Pagani, E; Falcinelli, S; Pepponi, R; Perrera, C; Haider, R; Castiglia, D; Ferranti, G; Bonmassar, E; Jiricny, J; Zambruno, G; D'Atri, S (2002). High-frequency microsatellite instability is associated with defective DNA mismatch repair in human melanoma. Journal of Investigative Dermatology, 118(1):79-86.

Räschle, M; Dufner, P; Marra, G; Jiricny, J (2002). Mutations within the hMLH1 and hPMS2 subunits of the human MutLalpha mismatch repair factor affect its ATPase activity, but not its ability to interact with hMutSalpha. Journal of Biological Chemistry, 277(24):21810-21820.

Chang, C L; Marra, G; Chauhan, D P; Ha, H T; Chang, D K (2002). Oxidative stress inactivates the human DNA mismatch repair system. American Journal of Physiology. Cell Physiology, 283(1):C148-C154.

Pedrazzi, G; Perrera, C; Blaser, H; Kuster, P; Marra, G; Davies, S L; Ryu, G H; Freire, R; Hickson, I D; Jiricny, J; Stagljar, I (2001). Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1. Nucleic Acids Research, 29(21):4378-4386.

Percesepe, A; Borghi, F; Menigatti, M; Losi, L; Foroni, M; Di Gregorio, C; Rossi, G; Pedroni, M; Sala, E; Vaccina, F; Roncucci, L; Benatti, P; Viel, A; Genuardi, M; Marra, G; Kristo, P; Peltomäki, P; Ponz de Leon, M (2001). Molecular screening for hereditary nonpolyposis colorectal cancer: a prospective, population-based study. Journal of Clinical Oncology, 19(19):3944-3950.

Heinimann, K; Thompson, A; Locher, A; Furlanetto, T; Bader, E; Wolf, A; Meier, R; Walter, K; Bauerfeind, P; Marra, G; Müller, H; Foernzler, D; Dobbie, Z (2001). Nontruncating APC germ-line mutations and mismatch repair deficiency play a minor role in APC mutation-negative polyposis. Cancer Research, 61(20):7616-7622.

Marra, G; D'Atri, S; Yan, H; Perrera, C; Cannavo', E; Vogelstein, B; Jiricny, J (2001). Phenotypic analysis of hMSH2 mutations in mouse cells carrying human chromosomes. Cancer Research, 61(21):7719-7721.

Marra, G; D'Atri, S; Corti, C; Bonmassar, L; Cattaruzza, M S; Schweizer, P; Heinimann, K; Bartosova, Z; Nyström-Lahti, M; Jiricny, J (2001). Tolerance of human MSH2+/- lymphoblastoid cells to the methylating agent temozolomide. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 98(13):7164-7169.

Kleczkowska, H E; Marra, G; Lettieri, T; Jiricny, J (2001). hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci. Genes and Development, 15(6):724-736.

Yan, H; Papadopoulos, N; Marra, G; Perrera, C; Jiricny, J; Boland, C R; Lynch, H T; Chadwick, R B; de la Chapelle, A; Berg, K; Eshleman, J R; Yuan, W; Markowitz, S; Laken, S J; Lengauer, C; Kinzler, K W; Vogelstein, B (2000). Conversion of diploidy to haploidy. Nature, 403(6771):723-724.

Ichikawa, M; Nakane, H; Marra, G; Corti, C; Jiricny, J; Fitch, M; Ford, J M; Ikejima, M; Shimada, T; Yoshino, M; Takeuchi, S; Nakatsu, Y; Tanaka, K (2000). Decreased UV sensitivity, mismatch repair activity and abnormal cell cycle checkpoints in skin cancer cell lines derived from UVB-irradiated XPA-deficient mice. Mutation Research, 459(4):285-298.

Dufner, P; Marra, G; Räschle, M; Jiricny, J (2000). Mismatch recognition and DNA-dependent stimulation of the ATPase activity of hMutSalpha is abolished by a single mutation in the hMSH6 subunit. Journal of Biological Chemistry, 275(47):36550-36555.

Zhang, H; Marra, G; Jiricny, J; Maher, V M; McCormick, J J (2000). Mismatch repair is required for O(6)-methylguanine-induced homologous recombination in human fibroblasts. Carcinogenesis, 21(9):1639-1646.

Iaccarino, I; Marra, G; Dufner, P; Jiricny, J (2000). Mutation in the magnesium binding site of hMSH6 disables the hMutSalpha sliding clamp from translocating along DNA. Journal of Biological Chemistry, 275(3):2080-2086.

Räschle, M; Marra, G; Nyström-Lahti, M; Schär, P; Jiricny, J (1999). Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1. Journal of Biological Chemistry, 274(45):32368-32375.

Marra, G; Iaccarino, I; Lettieri, T; Roscilli, G; Delmastro, P; Jiricny, J (1998). Mismatch repair deficiency associated with overexpression of the MSH3 gene. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 95(15):8568-8573.

Iaccarino, I; Marra, G; Palombo, F; Jiricny, J (1998). hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha. EMBO Journal, 17(9):2677-2686.

Marra, G; Chang, C L; Laghi, L A; Chauhan, D P; Young, D; Boland, C R (1996). Expression of human MutS homolog 2 (hMSH2) protein in resting and proliferating cells. Oncogene, 13(10):2189-2196.

Marra, G; Boland, C R (1995). Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives. Journal of the National Cancer Institute, 87(15):1114-1125.

Marra, G; Anti, M; Percesepe, A; Armelao, F; Ficarelli, R; Coco, C; Rinelli, A; Vecchio, F M; D'Arcangelo, E (1994). Circadian variations of epithelial cell proliferation in human rectal crypts. Gastroenterology, 106(4):982-987.

Anti, M; Armelao, F; Marra, G; Percesepe, A; Bartoli, G M; Palozza, P; Parrella, P; Canetta, C; Gentiloni, N; De Vitis, I (1994). Effects of different doses of fish oil on rectal cell proliferation in patients with sporadic colonic adenomas. Gastroenterology, 107(6):1709-1718.

Anti, M; Marra, G; Armelao, F; Bartoli, G M; Ficarelli, R; Percesepe, A; De Vitis, I; Maria, G; Sofo, L; Rapaccini, G L (1992). Effect of omega-3 fatty acids on rectal mucosal cell proliferation in subjects at risk for colon cancer. Gastroenterology, 103(3):883-891.

This list was generated on Thu Jun 20 09:30:35 2019 CEST.