Deuel, J W; Schaer, C A; Boretti, F S; Opitz, L; Garcia-Rubio, I; Baek, J H; Spahn, D R; Buehler, P W; Schaer, D J (2016). Hemoglobinuria-related acute kidney injury is driven by intrarenal oxidative reactions triggering a heme toxicity response. Cell Death and Disease, 7:e2064.
Deuel, J W; Puglia, M; Buehler, P W; Schaer, C A; Vallelian, Florence; Schaer, D (2015). Different target specificities of haptoglobin and hemopexin define a sequential protection system against vascular hemoglobin toxicity. Free Radical Biology & Medicine, 89:931-943.
Vallelian, F; Deuel, J W; Opitz, L; Schaer, C A; Puglia, M; Lönn, M; Engelsberger, W; Schauer, S; Karnaukhova, E; Spahn, D R; Stocker, R; Buehler, P W; Schaer, D J (2015). Proteasome inhibition and oxidative reactions disrupt cellular homeostasis during heme stress. Cell Death and Differentiation, 22(4):597-611.
Schaer, C A; Deuel, J W; Bittermann, A G; Rubio, I G; Schoedon, G; Spahn, D R; Wepf, R A; Vallelian, F; Schaer, D J (2013). Mechanisms of haptoglobin protection against hemoglobin peroxidation triggered endothelial damage. Cell Death and Differentiation, 20(11):1569-1579.
Vallelian, F; Schaer, C A; Kaempfer, T; Gehrig, P; Duerst, E; Schoedon, G; Schaer, D J (2010). Glucocorticoid treatment skews human monocyte differentiation into a hemoglobin-clearance phenotype with enhanced heme-iron recycling and antioxidant capacity. Blood, 116(24):5347-5356.
Schaer, C A; Vallelian, F; Imhof, A; Schoedon, G; Schaer, D J (2008). Heme carrier protein (HCP-1) spatially interacts with the CD163 hemoglobin uptake pathway and is a target of inflammatory macrophage activation. Journal of Leukocyte Biology, 83(2):325-333.