Rochat, M A; Schlaepfer, E; Speck, R F (2017). Promising role of toll-like receptor 8 agonist in concert with prostratin for activation of silent HIV. Journal of Virology, 91(4):e02084-16.
Miller, R C; Schlaepfer, E; Baenziger, S; Crameri, R; Zeller, S; Byland, R; Audigé, A; Nadal, D; Speck, R F (2011). HIV interferes with SOCS-1 and -3 expression levels driving immune activation. European Journal of Immunology, 41(4):1058-1069.
Schlaepfer, E; Speck, R F (2011). TLR8 activates HIV from latently infected cells of myeloid-monocytic origin directly via the MAPK pathway and from latently infected CD4+ T cells indirectly via TNF-α. Journal of Immunology, 186(7):4314-4324.
Hofer, U; Schlaepfer, E; Baenziger, S; Nischang, M; Regenass, S; Schwendener, R; Kempf, W; Nadal, D; Speck, R F (2010). Inadequate clearance of translocated bacterial products in HIV-infected humanized mice. PLoS Pathogens, 6(4):e1000867.
Audigé, A; Schlaepfer, E; von Wyl, V; Miller, R C; Vernazza, P; Nadal, D; Speck, R F (2010). B cells from HIV-infected patients with primary central nervous system lymphoma display an activated phenotype and have a blunted TNF-α response to TLR9 triggering. AIDS Research and Human Retroviruses, 26(10):1063-1074.
Baenziger, S; Heikenwalder, M; Johansen, P; Schlaepfer, E; Hofer, U; Miller, R; Diemand, S; Honda, K; Kundig, T M; Aguzzi, A; Speck, R F (2009). Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology. Blood, 113(2):377-388.
Hofer, U; Baenziger, S; Heikenwalder, M; Schlaepfer, E; Gehre, N; Regenass, S; Brunner, T; Speck, R F (2008). RAG2-/- gamma(c)-/- mice transplanted with CD34+ cells from human cord blood show low levels of intestinal engraftment and are resistant to rectal transmission of human immunodeficiency virus. Journal of Virology, 82(24):12145-12153.
Schlaepfer, E; Speck, R F (2008). Anti-HIV activity mediated by natural killer and CD8+ cells after toll-like receptor 7/8 triggering. PLoS ONE, 3(4):e1999.
Baenziger, S; Tussiwand, R; Schlaepfer, E; Mazzucchelli, L; Heikenwalder, M; Kurrer, M O; Behnke, S; Frey, J; Oxenius, A; Joller, H; Aguzzi, A; Manz, M G; Speck, R F (2006). Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 103(43):15951-15956.
Oxenius, A; Price, D A; Hersberger, M; Schlaepfer, E; Weber, R; Weber, M; Kundig, T M; Böni, J; Joller, H; Phillips, R E; Flepp, M; Opravil, M; Speck, R F (2004). HIV-specific cellular immune response is inversely correlated with disease progression as defined by decline of CD4+ T cells in relation to HIV RNA load. Journal of Infectious Diseases, 189(7):1199-1208.