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Ali, Izna; Khalid, Seher; Stieger, Bruno; Brouwer, Kim L R (2019). Effect of a Common Genetic Variant (p.V444A) in the Bile Salt Export Pump on the Inhibition of Bile Acid Transport by Cholestatic Medications. Molecular Pharmaceutics, 16(3):1406-1411.

Sargiacomo, Camillo; El-Kehdy, Hoda; Pourcher, Guillaume; Stieger, Bruno; Najimi, Mustapha; Sokal, Etienne (2018). Age-dependent glycosylation of the sodium taurocholate cotransporter polypeptide: From fetal to adult human livers. Hepatology Communications, 2(6):693-702.

Tournier, Nicolas; Stieger, Bruno; Langer, Oliver (2018). Imaging techniques to study drug transporter function in vivo. Pharmacology & Therapeutics, 189:104-122.

Rau, Monika; Schmitt, Johannes; Berg, Thomas; Kremer, Andreas E; Stieger, Bruno; Spanaus, Katharina; Bengsch, Bertram; Romero, Marta R; Marin, Jose J; Keitel, Verena; Klinker, Hartwig; Tony, Hans-Peter; Müllhaupt, Beat; Geier, Andreas (2018). Serum IP-10 levels and increased DPPIV activity are linked to circulating CXCR3+ T cells in cholestatic HCV patients. PLoS ONE, 13(12):e0208225.

Chedik, Lisa; Bruyere, Arnaud; Le Vee, Marc; Stieger, Bruno; Denizot, Claire; Parmentier, Yannick; Potin, Sophie; Fardel, Olivier (2017). Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin. PLoS ONE, 12(1):e0169480.

Bruyere, Arnaud; Hubert, Céline; Le Vee, Marc; Chedik, Lisa; Sayyed, Katia; Stieger, Bruno; Denizot, Claire; Parmentier, Yannick; Fardel, Olivier (2017). Inhibition of SLC drug transporter activities by environmental bisphenols. Toxicology in Vitro, 40:34-44.

Stieger, Bruno; Mahdi, Zainab M; Jäger, Walter (2017). Intestinal and hepatocellular transporters: therapeutic effects and drug interactions of herbal supplements. Annual Review of Pharmacology and Toxicology, 57(1):399-416.

Stieger, Bruno; Mahdi, Zainab M (2017). Model Systems for Studying the Role of Canalicular Efflux Transporters in Drug-Induced Cholestatic Liver Disease. Journal of Pharmaceutical Sciences, 106(9):2295-2301.

Mayati, Abdullah; Moreau, Amélie; Le Vée, Marc; Stieger, Bruno; Denizot, Claire; Parmentier, Yannick; Fardel, Olivier (2017). Protein Kinases C-Mediated Regulations of Drug Transporter Activity, Localization and Expression. International Journal of Molecular Sciences, 18(4):764.

Nicolaï, Johan; Thevelin, Louise; Bing, Qi; Stieger, Bruno; Chanteux, Hugues; Augustijns, Patrick; Annaert, Pieter (2017). Role of the OATP Transporter Family and a Benzbromarone-SensitiveEfflux Transporter in the Hepatocellular Disposition of Vincristine. Pharmaceutical Research, 34(11):2336-2348.

Mayati, Abdullah; Moreau, Amélie; Denizot, Claire; Stieger, Bruno; Parmentier, Yannick; Fardel, Olivier (2017). β2-adrenergic receptor-mediated in vitro regulation of human hepatic drug transporter expression by epinephrine. European Journal of Pharmaceutical Sciences, 106:302-312.

Rau, Monika; Stieger, Bruno; Monte, Maria J; Schmitt, Johannes; Jahn, Daniel; Frey-Wagner, Isabelle; Raselli, Tina; Marin, Jose J G; Müllhaupt, Beat; Rogler, Gerhard; Geier, Andreas (2016). Alterations in enterohepatic Fgf15 signaling and changes in bile acid composition depend on localization of murine intestinal inflammation. Inflammatory Bowel Diseases, 22(10):2382-2389.

Sayyed, Katia; Vee, Marc Le; Abdel-Razzak, Ziad; Jouan, Elodie; Stieger, Bruno; Denizot, Claire; Parmentier, Yannick; Fardel, Olivier (2016). Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate. Toxicology, 363-364:58-71.

Mahdi, Zainab M; Synal-Hermanns, Uta; Yoker, Aylin; Locher, Kaspar P; Stieger, Bruno (2016). Role of Multidrug Resistance Protein 3 in Antifungal-Induced Cholestasis. Molecular Pharmacology, 90(1):23-34.

Lušin, Tina Trdan; Mrhar, Aleš; Stieger, Bruno; Kristl, Albin; Berginc, Katja; Trontelj, Jurij (2016). Efflux and uptake transporters involved in the disposition of bazedoxifene. European Journal of Drug Metabolism and Pharmacokinetics, 41(3):251-257.

De Bruyn, Tom; Stieger, Bruno; Augustijns, Patrick F; Annaert, Pieter P (2016). Clearance Prediction of HIV Protease Inhibitors in Man: Role of Hepatic Uptake. Journal of Pharmaceutical Sciences, 105(2):854-863.

Montanari, Floriane; Pinto, Marta; Khunweeraphong, Narakorn; Wlcek, Katrin; Sohail, M Imran; Noeske, Tobias; Boyer, Scott; Chiba, Peter; Stieger, Bruno; Kuchler, Karl; Ecker, Gerhard F (2016). Flagging Drugs That Inhibit the Bile Salt Export Pump. Molecular Pharmaceutics, 13(1):163-171.

Wanek, Thomas; Halilbasic, Emina; Visentin, Michele; Mairinger, Severin; Römermann, Kerstin; Stieger, Bruno; Kuntner, Claudia; Müller, Markus; Langer, Oliver; Trauner, Michael (2016). Influence of 24-Nor-Ursodeoxycholic Acid on Hepatic Disposition of [(18)F]Ciprofloxacin, a Positron Emission Tomography Study in Mice. Journal of Pharmaceutical Sciences, 105(1):106-112.

Chaubey, Pururawa Mayank; Hofstetter, Lia; Roschitzki, Bernd; Stieger, Bruno (2016). Proteomic Analysis of the Rat Canalicular Membrane Reveals Expression of a Complex System of P4-ATPases in Liver. PLoS ONE, 11(6):e0158033.

Stieger, Bruno; Hagenbuch, Bruno (2016). Recent advances in understanding hepatic drug transport. F1000Research, 5:2465.

Patik, Izabel; Kovacsics, Daniella; Német, Orsolya; Gera, Melinda; Várady, György; Stieger, Bruno; Hagenbuch, Bruno; Szakács, Gergely; Özvegy-Laczka, Csilla (2015). Functional expression of the 11 human Organic Anion Transporting Polypeptides in insect cells reveals that sodium fluorescein is a general OATP substrate. Biochemical Pharmacology, 98(4):649-658.

Mayati, Abdullah; Le Vee, Marc; Moreau, Amélie; Jouan, Elodie; Bucher, Simon; Stieger, Bruno; Denizot, Claire; Parmentier, Yannick; Fardel, Olivier (2015). Protein kinase C-dependent regulation of human hepatic drug transporter expression. Biochemical Pharmacology, 98(4):703-717.

Visentin, Michele; Stieger, Bruno; Merz, Michael; Kullak-Ublick, Gerd A (2015). Octreotide Inhibits the Bilirubin Carriers Organic Anion Transporting Polypeptides 1B1 and 1B3 and the Multidrug Resistance-Associated Protein 2. Journal of Pharmacology and Experimental Therapeutics, 355(2):145-151.

Gao, Bo; Vavricka, Stephan R; Meier, Peter J; Stieger, Bruno (2015). Differential cellular expression of organic anion transporting peptides OATP1A2 and OATP2B1 in the human retina and brain: implications for carrier-mediated transport of neuropeptides and neurosteriods in the CNS. Pflügers Archiv : European Journal of Physiology, 467(7):1481-1493.

Slijepcevic, Davor; Kaufman, Christina; Wichers, Catharina G K; Gilglioni, Eduardo H; Lempp, Florian A; Duijst, Suzanne; de Waart, Dirk R; Oude Elferink, Ronald P J; Mier, Walter; Stieger, Bruno; Beuers, Ulrich; Urban, Stephan; van de Graaf, Stan F J (2015). Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice. Hepatology, 62(1):207-219.

Bachour-El Azzi, Pamela; Sharanek, Ahmad; Burban, Audrey; Li, Ruoya; Guével, Rémy Le; Abdel-Razzak, Ziad; Stieger, Bruno; Guguen-Guillouzo, Christiane; Guillouzo, André (2015). Comparative localization and functional activity of the main hepatobiliary transporters in HepaRG cells and primary human hepatocytes. Toxicological Sciences, 145(1):157-168.

Le Vee, Marc; Jouan, Elodie; Noel, Gregory; Stieger, Bruno; Fardel, Olivier (2015). Polarized location of SLC and ABC drug transporters in monolayer-cultured human hepatocytes. Toxicology in Vitro, 29(5):938-946.

Stieger, Bruno; Gao, Bo (2015). Drug transporters in the central nervous system. Clinical Pharmacokinetics, 54(3):225-242.

Brenner, Stefan; Riha, Juliane; Giessrigl, Benedikt; Thalhammer, Theresia; Grusch, Michael; Krupitza, Georg; Stieger, Bruno; Jäger, Walter (2015). The effect of organic anion-transporting polypeptides 1B1, 1B3 and 2B1 on the antitumor activity of flavopiridol in breast cancer cells. International Journal of Oncology, 46(1):324-332.

Hegedűs, Tamás; Chaubey, Pururawa Mayank; Várady, György; Szabó, Edit; Sarankó, Hajnalka; Hofstetter, Lia; Roschitzki, Bernd; Stieger, Bruno; Sarkadi, Balázs (2015). Inconsistencies in the red blood cell membrane proteome analysis: generation of a database for research and diagnostic applications. Database, 2015:online.

Schmitt, Johannes; Kong, Bo; Stieger, Bruno; Tschopp, Oliver; Schultze, Simon M; Rau, Monika; Weber, Achim; Muellhaupt, Beat; Guo, Grace L; Geier, Andreas (2015). Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal. Liver International, 35(4):1133-1144.

Le Vee, Marc; Jouan, Elodie; Stieger, Bruno; Lecureur, Valérie; Fardel, Olivier (2015). Regulation of human hepatic drug transporter activity and expression by diesel exhaust particle extract. PLoS ONE, 10(3):e0121232.

Stieger, Bruno; Unadkat, Jashvant D; Prasad, Bhagwat; Langer, Oliver; Gali, Hariprasad (2014). Role of (drug) transporters in imaging in health and disease. Drug Metabolism and Disposition, 42(12):2007-2015.

Riha, Juliane; Brenner, Stefan; Böhmdorfer, Michaela; Giessrigl, Benedikt; Pignitter, Marc; Schueller, Katharina; Thalhammer, Theresia; Stieger, Bruno; Somoza, Veronika; Szekeres, Thomas; Jäger, Walter (2014). Resveratrol and its major sulfated conjugates are substrates of organic anion transporting polypeptides (OATPs): impact on growth of ZR-75-1 breast cancer cells. Molecular Nutrition & Food Research, 58(9):1830-1842.

Gai, Zhibo; Hiller, Christian; Chin, Siew Hung; Hofstetter, Lia; Stieger, Bruno; Konrad, Daniel; Kullak-Ublick, Gerd A (2014). Uninephrectomy augments the effects of high fat diet induced obesity on gene expression in mouse kidney. Biochimica et Biophysica Acta, 1842(9):1870-1878.

Stieger, Bruno; Kullak-Ublick, Gerd A (2014). Arzneimittel-Interaktionen auf der Ebene von Transportern des Hepatozyten. Pharmazeutische Medizin, 16(1):36-41.

Stieger, Bruno; Hagenbuch, Bruno (2014). Organic anion-transporting polypeptides. Current Topics in Membranes, 73:205-32.

Russmann, Stefan; Niedrig, David F; Budmiger, Mathias; Schmidt, Caroline; Stieger, Bruno; Hürlimann, Sandra; Kullak-Ublick, Gerd A (2014). Rivaroxaban postmarketing risk of liver injury. Journal of Hepatology, 61(2):293-300.

Anwer, M Sawkat; Stieger, Bruno (2014). Sodium-dependent bile salt transporters of the SLC10A transporter family: more than solute transporters. Pflügers Archiv : European Journal of Physiology, 466(1):77-89.

Pastor, Catherine M; Müllhaupt, Beat; Stieger, Bruno (2014). The role of organic anion transporters in diagnosing liver diseases by magnetic resonance imaging. Drug Metabolism and Disposition, 42(4):675-684.

Wlcek, Katrin; Hofstetter, Lia; Stieger, Bruno (2014). Transport of estradiol-17β-glucuronide, estrone-3-sulfate and taurocholate across the endoplasmic reticulum membrane: evidence for different transport systems. Biochemical Pharmacology, 88(1):106-118.

Dayal, Jasbani H S; Cole, Clare L; Pourreyron, Celine; Watt, Stephen A; Lim, Yok Zuan; Salas-Alanis, Julio C; Murrell, Dedee F; McGrath, John A; Stieger, Bruno; Jahoda, Colin; Leigh, Irene M; South, Andrew P (2014). Type VII collagen regulates expression of OATP1B3, promotes front-to-rear polarity and increases structural organisation in 3D spheroid cultures of RDEB tumour keratinocytes. Journal of Cell Science, 127(Pt 4):740-751.

Stieger, Bruno; Kullak-Ublick, Gerd A (2013). Bile salt Export Pump BSEP (ABCB11): Role in liver physiology and liver disease. In: Ishikawa, T; Kim, R B; König, J. Pharmacogenomics of Human Drug Transporters: Clinical Impacts. Hoboken, NJ, USA: Wiley-Blackwell, 295-309.

Ontsouka, Edgar Corneille; Huang, Xiao; Stieger, Bruno; Albrecht, Christiane (2013). Characteristics and functional relevance of apolipoprotein-A1 and cholesterol binding in mammary gland tissues and epithelial cells. PLoS ONE, 8(7):e70407.

Le Vee, Marc; Jouan, Elodie; Stieger, Bruno; Fardel, Olivier (2013). Differential regulation of drug transporter expression by all-trans retinoic acid in hepatoma HepaRG cells and human hepatocytes. European Journal of Pharmaceutical Sciences, 48(4-5):767-774.

Noel, Gregory; Le Vee, Marc; Moreau, Amélie; Stieger, Bruno; Parmentier, Yannick; Fardel, Olivier (2013). Functional expression and regulation of drug transporters in monolayer- and sandwich-cultured mouse hepatocytes. European Journal of Pharmaceutical Sciences, 49(1):39-50.

Nies, Anne T; Niemi, Mikko; Burk, Oliver; Winter, Stefan; Zanger, Ulrich M; Stieger, Bruno; Schwab, Matthias; Schaeffeler, Elke (2013). Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1. Genome Medicine, 5:1.

Wlcek, Katrin; Koller, Fabienne; Ferenci, Peter; Stieger, Bruno (2013). Hepatocellular organic anion-transporting polypeptides (OATPs) and multidrug resistance-associated protein 2 (MRP2) are inhibited by silibinin. Drug Metabolism and Disposition, 41(8):1522-1528.

Hoekstra, Lisette T; de Graaf, Wilmar; Nibourg, Geert A A; Heger, Michal; Bennink, Roelof J; Stieger, Bruno; van Gulik, Thomas M (2013). Physiological and biochemical basis of clinical liver function tests: a review. Annals of Surgery, 257(1):27-36.

Le Vee, Marc; Noel, Gregory; Jouan, Elodie; Stieger, Bruno; Fardel, Olivier (2013). Polarized expression of drug transporters in differentiated human hepatoma HepaRG cells. Toxicology in Vitro, 27(6):1979-1986.

Stieger, Bruno; Kullak-Ublick, Gerd A (2013). Role of membrane transport in hepatotoxicity and pathogenesis of drug-induced cholestasis. In: Kaplowitz, N; DeLeve, L D. Drug-Induced Liver Disease. unknown: Elsevier, 123-133.

De Bruyn, Tom; van Westen, Gerard J P; Ijzerman, Adriaan P; Stieger, Bruno; de Witte, Peter; Augustijns, Patrick F; Annaert, Pieter P (2013). Structure-based identification of OATP1B1/3 inhibitors. Molecular Pharmacology, 83(6):1257-1267.

Hagenbuch, Bruno; Stieger, Bruno (2013). The SLCO (former SLC21) superfamily of transporters. Molecular Aspects of Medicine, 34(2-3):396-412.

Egert, Aurélie; Peters, Shaun; Guyot, Christelle; Stieger, Bruno; Keller, Felix (2012). An Arabidopsis T-DNA insertion mutant for galactokinase (AtGALK, At3g06580) hyperaccumulates free galactose and is insensitive to exogenous galactose. Plant & Cell Physiology, 53(5):921-929.

Schmitt, Johannes; Roderfeld, Martin; Sabrane, Karim; Zhang, Pan; Tian, Yinghua; Mertens, Joachim C; Frei, Pascal; Stieger, Bruno; Weber, Achim; Müllhaupt, Beat; Roeb, Elke; Geier, Andreas (2012). Complement factor C5 deficiency significantly delays the progression of biliary fibrosis in bile duct-ligated mice. Biochemical and Biophysical Research Communications (BBRC), 418(3):445-450.

Huster, Dominik; Kühne, Angelika; Bhattacharjee, Ashima; Raines, Lily; Jantsch, Vanessa; Noe, Johannes; Schirrmeister, Wiebke; Sommerer, Ines; Sabri, Osama; Berr, Frieder; Mössner, Joachim; Stieger, Bruno; Caca, Karel; Lutsenko, Svetlana (2012). Diverse Functional Properties of Wilson Disease ATP7B Variants. Gastroenterology, 142(4):947-956.e5.

Many, Natalie; Stickel, Felix; Schmitt, Johannes; Stieger, Bruno; Soyka, Michael; Frei, Pascal; Götze, Oliver; Müllhaupt, Beat; Geier, Andreas (2012). Genetic variations in bile acid homeostasis are not overrepresented in alcoholic cirrhosis compared to patients with heavy alcohol abuse and absent liver disease. Mutagenesis, 27(5):567-572.

Trdan Lušin, Tina; Mrhar, Aleš; Stieger, Bruno; Kullak-Ublick, Gerd A; Marc, Janja; Ostanek, Barbara; Zavratnik, Andrej; Kristl, Albin; Berginc, Katja; Delić, Katja; Trontelj, Jurij (2012). Influence of hepatic and intestinal efflux transporters and their genetic variants on the pharmacokinetics and pharmacodynamics of raloxifene in osteoporosis treatment. Translational Research, 160(4):298-308.

Trdan Lušin, Tina; Stieger, Bruno; Marc, Janja; Mrhar, Aleš; Trontelj, Jurij; Zavratnik, Andrej; Ostanek, Barbara (2012). Organic anion transporting polypeptides OATP1B1 and OATP1B3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifene. Journal of Translational Medicine, 10:76.

Jang, Jae-Hwi; Rickenbacher, Andreas; Humar, Bostjan; Weber, Achim; Raptis, Dimitri Aristotle; Lehmann, Kuno; Stieger, Bruno; Moritz, Wolfgang; Soll, Christopher; Georgiev, Panco; Fischer, David; Laczko, Endre; Graf, Rolf; Clavien, Pierre-Alain (2012). Serotonin protects mouse liver from cholestatic injury by decreasing bile salt pool after bile duct ligation. Hepatology, 56(1):209-218.

Baur, Katharina; Mertens, Joachim C; Schmitt, Johannes; Iwata, Rika; Stieger, Bruno; Frei, Pascal; Seifert, Burkhardt; Ferrari, Heike A Bischoff; von Eckardstein, Arnold; Müllhaupt, Beat; Geier, Andreas (2012). The vitamin D receptor gene bAt (CCA) haplotype impairs the response to pegylated-interferon/ribavirin-based therapy in chronic hepatitis C patients. Antiviral Therapy, 17(3):541-547.

Pauli-Magnus, Christiane; Meier, Peter J; Stieger, Bruno (2010). Genetic determinants of drug-induced cholestasis and intrahepatic cholestasis of pregnancy. Seminars in Liver Disease, 30(2):147-159.

Martin, Ina V; Schmitt, Johannes; Minkenberg, Alexander; Mertens, Joachim C; Stieger, Bruno; Müllhaupt, Beat; Geier, Andreas (2010). Bile acid retention and activation of endogenous hepatic farnesoid-X-receptor in the pathogenesis of fatty liver disease in ob/ob-mice. Biological Chemistry, 391(12):1441-1449.

Peters, Rowayda; Wolf, Monika J; van den Broek, Maries; Nuvolone, Mario; Dannenmann, Stefanie; Stieger, Bruno; Rapold, Reto; Konrad, Daniel; Rubin, Arnold; Bertino, Joseph R; Aguzzi, Adriano; Heikenwalder, Mathias; Knuth, Alexander K (2010). Efficient generation of multipotent mesenchymal stem cells from umbilical cord blood in stroma-free liquid culture. PLoS ONE, 5(12):e15689.

Stieger, Bruno; Meier, Yvonne; Meier, Peter J (2007). The bile salt export pump. Pflügers Archiv : European Journal of Physiology, 453(5):611-620.

Stieger, Bruno; Higgins, Christopher F (2007). Twenty years of ATP-binding cassette (ABC) transporters. Pflügers Archiv : European Journal of Physiology, 453(5):543.

Hoekstra, Harm; Porte, Robert J; Tian, Yinghua; Jochum, Wolfram; Stieger, Bruno; Moritz, Wolfgang; Slooff, Maarten J H; Graf, Rolf; Clavien, Pierre A (2006). Bile salt toxicity aggravates cold ischemic injury of bile ducts after liver transplantation in Mdr2+/- mice. Hepatology, 43(5):1022-1031.

Noe, Johannes; Kullak-Ublick, Gerd A; Jochum, Wolfram; Stieger, Bruno; Kerb, Reinhold; Haberl, Michael; Müllhaupt, Beat; Meier, Peter J; Pauli-Magnus, Christiane (2005). Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis. Journal of Hepatology, 43(3):536-543.

Kullak-Ublick, Gerd A; Ismair, Manfred G; Kubitz, Ralf; Schmitt, Marcus; Häussinger, Dieter; Stieger, Bruno; Hagenbuch, Bruno; Meier, Peter J; Beuers, Ulrich; Paumgartner, Gustav (2000). Stable expression and functional characterization of a Na+-taurocholate cotransporting green fluorescent protein in human hepatoblastoma HepG2 cells. Cytotechnology, 34(1/2):1-9.

This list was generated on Tue Jun 18 19:07:06 2019 CEST.