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Number of items: 40.

Neumann, Elena; Ralvenius, William T; Acuña, Mario A; Rudolph, Uwe; Zeilhofer, Hanns Ulrich (2018). TP003 is a non-selective benzodiazepine site agonist that induces anxiolysis via α2GABA receptors. Neuropharmacology, 143:71-78.

Ralvenius, William T; Neumann, Elena; Pagani, Martina; Acuña, Mario A; Wildner, Hendrik; Benke, Dietmar; Fischer, Nina; Rostaher, Ana; Schwager, Simon; Detmar, Michael; Frauenknecht, Katrin; Aguzzi, Adriano; Hubbs, Jed Lee; Rudolph, Uwe; Favrot, Claude; Zeilhofer, Hanns Ulrich (2018). Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors. Nature Communications, 9(1):3230.

Zeilhofer, Hanns Ulrich; Neumann, Elena; Munro, Gordon (2018). Spinal GABAA receptors for pain control-Lost in translation? Pain, 159(9):1675-1676.

Huang, Jing; Polgár, Erika; Solinski, Hans Jürgen; Mishra, Santosh K; Tseng, Pang-Yen; Iwagaki, Noboru; Boyle, Kieran A; Dickie, Allen C; Kriegbaum, Mette C; Wildner, Hendrik; Zeilhofer, Hanns Ulrich; Watanabe, Masahiko; Riddell, John S; Todd, Andrew J; Hoon, Mark A (2018). Circuit dissection of the role of somatostatin in itch and pain. Nature Neuroscience, 21(5):707-716.

da Silva, Ronan V; Johannssen, Helge C; Wyss, Matthias T; Roome, R Brian; Bourojeni, Farin B; Stifani, Nicolas; Marsh, Ashley P L; Ryan, Monique M; Lockhart, Paul J; Leventer, Richard J; Richards, Linda J; Rosenblatt, Bernard; Srour, Myriam; Weber, Bruno; Zeilhofer, Hanns Ulrich; Kania, Artur (2018). DCC Is Required for the Development of Nociceptive Topognosis in Mice and Humans. Cell Reports, 22(5):1105-1114.

Klinger-Gratz, Pascal P; Ralvenius, William T; Neumann, Elena; Kato, Ako; Nyilas, Rita; Lele, Zsolt; Katona, István; Zeilhofer, Hanns Ulrich (2018). Acetaminophen Relieves Inflammatory Pain Through CB1 Cannabinoid Receptors in the Rostral Ventromedial Medulla. Journal of Neuroscience, 38(2):322-334.

Zeilhofer, Hanns Ulrich; Acuña, Mario A; Gingras, Jacinthe; Yévenes, Gonzalo E (2018). Glycine receptors and glycine transporters: targets for novel analgesics? Cellular and Molecular Life Sciences, 75(3):447-465.

Vuilleumier, Pascal Henri; Fritsche, Raphael; Schliessbach, Jürg; Schmitt, Bernhard; Arendt-Nielsen, Lars; Zeilhofer, Hanns Ulrich; Curatolo, Michele (2018). Mutations affecting glycinergic neurotransmission in hyperekplexia increase pain sensitivity. Brain : a journal of neurology, 141(1):63-71.

Albisetti, Gioele W; Ghanem, Alexander; Foster, Edmund; Conzelmann, Karl-Klaus; Zeilhofer, Hanns Ulrich; Wildner, Hendrik (2017). Identification of two classes of somatosensory neurons that display resistance to retrograde infection by rabies virus. Journal of Neuroscience, 37(43):10358-10371.

Haenraets, Karen; Foster, Edmund; Johannssen, Helge; Kandra, Vinnie; Frezel, Noémie; Steffen, Timothy; Jaramillo, Valeria; Paterna, Jean-Charles; Zeilhofer, Hanns Ulrich; Wildner, Hendrik (2017). Spinal nociceptive circuit analysis with recombinant adeno-associated viruses: the impact of serotypes and promoters. Journal of Neurochemistry, 142(5):721-733.

Müller Herde, Adrienne; Benke, Dietmar; Ralvenius, William T; Mu, Linjing; Schibli, Roger; Zeilhofer, Hanns Ulrich; Krämer, Stefanie D (2017). GABAA receptor subtypes in the mouse brain: Regional mapping and diazepam receptor occupancy by in vivo [18F]flumazenil PET. NeuroImage, 150:279-291.

Gasser, Emanuel; Johannssen, Helge C; Rülicke, Thomas; Zeilhofer, Hanns Ulrich; Stoffel, Markus (2016). Foxa1 is essential for development and functional integrity of the subthalamic nucleus. Scientific Reports, 6:38611.

Ghosh, Himanish; Auguadri, Luca; Battaglia, Sereina; Simone Thirouin, Zahra; Zemoura, Khaled; Messner, Simon; Acuña, Mario A; Wildner, Hendrik; Yévenes, Gonzalo E; Dieter, Andrea; Kawasaki, Hiroshi; O Hottiger, Michael; Zeilhofer, Hanns Ulrich; Fritschy, Jean-Marc; Tyagarajan, Shiva K (2016). Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission. Nature Communications, 7:13365.

Egan, Timothy James; Acuña, Mario A; Zenobi-Wong, Marcy; Zeilhofer, Hanns Ulrich; Urech, David (2016). Effects of N-Glycosylation of the human cation channel TRPA1 on agonist-sensitivity. Bioscience Reports, 36(5):e00390-e00390.

Ralvenius, William T; Acuña, Mario A; Benke, Dietmar; Matthey, Alain; Daali, Youssef; Rudolph, Uwe; Desmeules, Jules; Zeilhofer, Hanns Ulrich; Besson, Marie (2016). The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia. Neuropharmacology, 109:366-375.

Acuña, Mario A; Yévenes, Gonzalo E; Ralvenius, William T; Benke, Dietmar; Di Lio, Alessandra; Lara, Cesar O; Muñoz, Braulio; Burgos, Carlos F; Moraga-Cid, Gustavo; Corringer, Pierre-Jean; Zeilhofer, Hanns Ulrich (2016). Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain. Journal of Clinical Investigation, 126(7):2547-2560.

Behlke, Lauren M; Foster, Rachel A; Liu, Jing; Benke, Dietmar; Benham, Rebecca S; Nathanson, Anna J; Yee, Benjamin K; Zeilhofer, Hanns Ulrich; Engin, Elif; Rudolph, Uwe (2016). A pharmacogenetic 'restriction-of-function' approach reveals evidence for anxiolytic-like actions mediated by α5-containing GABAA receptors in mice. Neuropsychopharmacology, 41(10):2492-2501.

Mayrhofer, Johannes M; Haiss, Florent; Haenni, Dominik; Weber, Stefan; Zuend, Marc; Barrett, Matthew J P; Ferrari, Kim David; Maechler, Philipp; Saab, Aiman S; Stobart, Jillian L; Wyss, Matthias T; Johannssen, Helge; Osswald, Harald; Palmer, Lucy M; Revol, Vincent; Schuh, Claus-Dieter; Urban, Claus; Hall, Andrew; Larkum, Matthew E; Rutz-Innerhofer, Edith; Zeilhofer, Hanns Ulrich; Ziegler, Urs; Weber, Bruno (2015). Design and performance of an ultra-flexible two-photon microscope for in vivo research. Biomedical Optics Express, 6(11):4228-4237.

Schreiner, Bettina; Romanelli, Elisa; Liberski, Pawel; Ingold-Heppner, Barbara; Sobottka-Brillout, Bettina; Hartwig, Tom; Chandrasekar, Vijay; Johannssen, Helge; Zeilhofer, Hanns Ulrich; Aguzzi, Adriano; Heppner, Frank; Kerschensteiner, Martin; Becher, Burkhard (2015). Astrocyte depletion impairs redox homeostasis and triggers neuronal loss in the adult CNS. Cell Reports, 12(9):1377-1384.

Zeilhofer, Hanns Ulrich; Schmelz, Martin (2015). Local anesthetics take a central action in analgesia. Pain, 156(9):1579-1580.

Szabo, Nora E; da Silva, Ronan V; Sotocinal, Susana G; Zeilhofer, Hanns Ulrich; Mogil, Jeffrey S; Kania, Artur (2015). Hoxb8 intersection defines a role for lmx1b in excitatory dorsal horn neuron development, spinofugal connectivity, and nociception. Journal of Neuroscience, 35(13):5233-5246.

Ralvenius, William T; Benke, Dietmar; Acuña, Mario A; Rudolph, Uwe; Zeilhofer, Hanns Ulrich (2015). Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype. Nature Communications, 6(6803):online.

Hofer, Stefanie C; Ralvenius, William T; Gachet, M Salomé; Fritschy, Jean-Marc; Zeilhofer, Hanns Ulrich; Gertsch, Jürg (2015). Localization and production of peptide endocannabinoids in the rodent CNS and adrenal medulla. Neuropharmacology, 98:78-89.

Foster, Edmund; Wildner, Hendrik; Tudeau, Laetitia; Haueter, Sabine; Ralvenius, William T; Jegen, Monika; Johannssen, Helge; Hösli, Ladina; Haenraets, Karen; Ghanem, Alexander; Conzelmann, Karl-Klaus; Bösl, Michael; Zeilhofer, Hanns Ulrich (2015). TargeTed ablation, silencing, and activation establish glycinergic dorsal horn neurons as key components of a spinal gate for pain and itch. Neuron, 85(6):1289-1304.

Besson, Marie; Matthey, Alain; Daali, Youssef; Poncet, Antoine; Vuillemier, Pascal; Curatolo, Michele; Zeilhofer, Hanns Ulrich; Desmeules, Jules (2015). GABAergic modulation in central sensitization in humans: a randomized placebo-controlled pharmacokinetic-pharmacodynamic study comparing clobazam with clonazepam in healthy volunteers. Pain, 156(3):397-404.

Giber, Kristóf; Diana, Marco A; M Plattner, Viktor; Dugué, Guillaume P; Bokor, Hajnalka; Rousseau, Charly V; Maglóczky, Zsófia; Havas, László; Hangya, Balázs; Wildner, Hendrik; Zeilhofer, Hanns Ulrich; Dieudonné, Stéphane; Acsády, László (2015). A subcortical inhibitory signal for behavioral arrest in the thalamus. Nature Neuroscience, 18(4):562-568.

Zeilhofer, Hanns Ulrich; Ralvenius, William T; Acuña, Mario A (2015). Restoring the spinal pain gate: GABA(A) receptors as targets for novel analgesics. Advances in Pharmacology, 73:71-96.

Husson, Zoé; Rousseau, Charly V; Broll, Ilja; Zeilhofer, Hanns Ulrich; Dieudonné, Stéphane (2014). Differential GABAergic and glycinergic inputs of inhibitory interneurons and purkinje cells to principal cells of the cerebellar nuclei. Journal of Neuroscience, 34(28):9418-9431.

Maier, Patrick J; Zemoura, Khaled; Acuña, Mario A; Yévenes, Gonzalo E; Zeilhofer, Hanns Ulrich; Benke, Dietmar (2014). Ischemia-like oxygen and glucose deprivation mediates down-regulation of cell surface γ-aminobutyric acidB receptors via the endoplasmic reticulum (ER) stress-induced transcription factor CCAAT/enhancer-binding protein (C/EBP)-homologous protein (CHOP). Journal of Biological Chemistry, 289(18):12896-12907.

Harkany, Tibor; Zeilhofer, Hanns Ulrich; Cattaneo, Antonino (2014). Neurotrophin and endocannabinoid interactions in the neurobiology of pain. European Journal of Neuroscience, 39(3):331-333.

Hermann, Mario; Stillhard, Patrick; Wildner, Hendrik; Seruggia, Davide; Kapp, Viktor; Sánchez-Iranzo, Héctor; Mercader, Nadia; Montoliu, Lluís; Zeilhofer, Hanns Ulrich; Pelczar, Pawel (2014). Binary recombinase systems for high-resolution conditional mutagenesis. Nucleic Acids Research, 42(6):3894-3907.

Paul, Jolly; Yévenes, Gonzalo E; Benke, Dietmar; Lio, Alessandra Di; Ralvenius, William T; Witschi, Robert; Scheurer, Louis; Cook, James M; Rudolph, Uwe; Fritschy, Jean-Marc; Zeilhofer, Hanns Ulrich (2014). Antihyperalgesia by α2-GABAA receptors occurs via a genuine spinal action and does not involve supraspinal sites. Neuropsychopharmacology, 39(2):477-487.

Punnakkal, Pradeep; von Schoultz, Carolin; Haenraets, Karen; Wildner, Hendrik; Zeilhofer, Hanns Ulrich (2014). Morphological, biophysical and synaptic properties of glutamatergic neurons of the mouse spinal dorsal horn. Journal of Physiology, 592(4):759-776.

Tyagarajan, Shiva K; Ghosh, Himanish; Yévenes, Gonzalo E; Imanishi, Susumu Y; Zeilhofer, Hanns Ulrich; Gerrits, Bertran; Fritschy, Jean-Marc (2013). Extracellular signal-regulated kinase and glycogen synthase kinase 3β regulate gephyrin postsynaptic aggregation and GABAergic synaptic function in a calpain-dependent mechanism. Journal of Biological Chemistry, 288(14):9634-9647.

Besson, Marie; Daali, Youssef; Di Lio, Alessandra; Dayer, Pierre; Zeilhofer, Hanns Ulrich; Desmeules, Jules (2013). Antihyperalgesic effect of the GABA(A) Ligand clobazam in a neuropathic pain model in mice: a pharmacokinetic-pharmacodynamic study. Basic & Clinical Pharmacology & Toxicology, 112(3):192-197.

Zemoura, Khaled; Schenkel, Marisa; Acuña, Mario A; Yévenes, Gonzalo E; Zeilhofer, Hanns Ulrich; Benke, Dietmar (2013). Endoplasmic reticulum-associated degradation controls cell surface expression of γ-aminobutyric acid, type b receptors. Journal of Biological Chemistry, 288(48):34897-34905.

Wildner, Hendrik; Das Gupta, Rebecca; Bröhl, Dominique; Heppenstall, Paul A; Zeilhofer, Hanns Ulrich; Birchmeier, Carmen (2013). Genome-wide expression analysis of ptf1a- and ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticity. Journal of Neuroscience, 33(17):7299-7307.

Paul, Jolly; Zeilhofer, Hanns Ulrich; Fritschy, Jean-Marc (2012). Selective distribution of GABA(A) receptor subtypes in mouse spinal dorsal horn neurons and primary afferents. Journal of Comparative Neurology, 520(17):3895-3911.

Kato, Ako; Punnakkal, Pradeep; Pernía-Andrade, Alejandro Javier; von Schoultz, Carolin; Sharopov, Salim; Nyilas, Rita; Katona, István; Zeilhofer, Hanns Ulrich (2012). Endocannabinoid-dependent plasticity at spinal nociceptor synapses. Journal of Physiology, 590(Pt 19):4717-4733.

Benke, Dietmar; Zeilhofer, Hanns Ulrich (2012). Divorce of obligatory partners in pain: disruption of GABA(B) receptor heterodimers in neuralgia. EMBO Journal, 31(15):3234-3236.

This list was generated on Tue Nov 13 06:00:18 2018 CET.