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Number of items at this level: 346.

2020

Bapst, Andreas M; Dahl, Sophie L; Knöpfel, Thomas; Wenger, Roland H (2020). Cre-mediated, loxP independent sequential recombination of a tripartite transcriptional stop cassette allows for partial read-through transcription. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms, 1863(8):194568.

Ruffell, Daniela (2020). Coronavirus SARS‐CoV‐2: filtering fact from fiction in the infodemic. FEBS letters, 594(7):1127-1131.

Olsen, Jeppe A; Alam, Amer; Kowal, Julia; Stieger, Bruno; Locher, Kaspar P (2020). Structure of the human lipid exporter ABCB4 in a lipid environment. Nature Structural & Molecular Biology, 27(1):62-70.

Salutari, Ilaria; Martin, Roland; Caflisch, Amedeo (2020). The 3A6-TCR/superagonist/HLA-DR2a complex shows similar interface and reduced flexibility compared to the complex with self-peptide. Proteins, 88(1):31-46.

2019

Schuler, Benjamin; Borgia, Alessandro; Borgia, Madeleine B; Heidarsson, Pétur O; Holmstrom, Erik D; Nettels, Daniel; Sottini, Andrea (2019). Binding without folding - the biomolecular function of disordered polyelectrolyte complexes. Current Opinion in Structural Biology, 60:66-76.

Kuon, Joel-E; Qi, Weihong; Schläpfer, Pascal; Hirsch-Hoffmann, Matthias; von Bieberstein, Philipp Rogalla; Patrignani, Andrea; Poveda, Lucy; Grob, Stefan; Keller, Miyako; Shimizu-Inatsugi, Rie; Grossniklaus, Ueli; Vanderschuren, Hervé; Gruissem, Wilhelm (2019). Haplotype-resolved genomes of geminivirus-resistant and geminivirus-susceptible African cassava cultivars. BMC Biology, 17(1):75.

Heller, Davide; Szklarczyk, Damian; von Mering, Christian (2019). Tree reconciliation combined with subsampling improves large scale inference of orthologous group hierarchies. BMC Bioinformatics, 20(1):228.

Allain, Frédéric H-T; Jinek, Martin (2019). Editorial overview: Protein-nucleic acid interactions - cryo-EM, what else? Current Opinion in Structural Biology, 59:vi-viii.

Denoth-Lippuner, Annina; Jessberger, Sebastian (2019). Mechanisms of cellular rejuvenation. FEBS letters, 593(23):3381-3392.

Kumar, Ananthanarayanan; Clerici, Marcello; Muckenfuss, Lena M; Passmore, Lori A; Jinek, Martin (2019). Mechanistic insights into mRNA 3'-end processing. Current Opinion in Structural Biology, 59:143-150.

Lemmin, Thomas; Soto, Cinque (2019). Glycosylator: a Python framework for the rapid modeling of glycans. BMC Bioinformatics, 20(1):513.

Radom, Filip; Paci, Emanuele; Plückthun, Andreas (2019). Computational Modeling of Designed Ankyrin Repeat Protein Complexes with Their Targets. Journal of Molecular Biology, 431(15):2852-2868.

van Gestel, Jordi; Kolter, Roberto (2019). When We Stop Thinking about Microbes as Cells. Journal of Molecular Biology, 431(14):2487-2492.

Hennet, Thierry (2019). Collagen glycosylation. Current Opinion in Structural Biology, 56:131-138.

Andres, Fabio; Iamele, Luisa; Meyer, Timo; Stüber, Jakob C; Kast, Florian; Gherardi, Ermanno; Niemann, Hartmut H; Plückthun, Andreas (2019). Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking. Journal of Molecular Biology, 431(10):2020-2039.

Khakzad, Hamed; Malmström, Johan; Malmström, Lars (2019). Greedy de novo motif discovery to construct motif repositories for bacterial proteomes. BMC Bioinformatics, 20(Suppl 4):141.

Wodak, Shoshana J; Paci, Emanuele; Dokholyan, Nikolay V; Berezovsky, Igor N; Horovitz, Amnon; Li, Jing; Hilser, Vincent J; Bahar, Ivet; Karanicolas, John; Stock, Gerhard; Hamm, Peter; Stote, Roland H; Eberhardt, Jerome; Chebaro, Yassmine; Dejaegere, Annick; Cecchini, Marco; Changeux, Jean-Pierre; Bolhuis, Peter G; Vreede, Jocelyne; Faccioli, Pietro; Orioli, Simone; Ravasio, Riccardo; Yan, Le; Brito, Carolina; Wyart, Matthieu; Gkeka, Paraskevi; Rivalta, Ivan; Palermo, Giulia; McCammon, J Andrew; Panecka-Hofman, Joanna; et al (2019). Allostery in Its Many Disguises: From Theory to Applications. Structure, 27(4):566-578.

Julius, U; Tselmin, S; Schatz, U; Fischer, S; Bornstein, S R (2019). Lipoprotein(a) and proprotein convertase subtilisin/kexin type 9 inhibitors. Clinical Research in Cardiology Supplements, 14(S1):45-50.

Julius, U; Tselmin, S; Schatz, U; Fischer, S; Bornstein, S R (2019). Lipoprotein(a)-an interdisciplinary challenge. Clinical Research in Cardiology Supplements, 14(S1):20-27.

Nave, Alexander Heinrich; von Eckardstein, Arnold (2019). Is lipoprotein(a) a risk factor for ischemic stroke and venous thromboembolism? Clinical Research in Cardiology Supplements, 14(Suppl 1):28-32.

Panasenko, Olesya O; Somasekharan, Syam Prakash; Villanyi, Zoltan; Zagatti, Marina; Bezrukov, Fedor; Rashpa, Ravish; Cornut, Julien; Iqbal, Jawad; Longis, Marion; Carl, Sarah H; Peña, Cohue; Panse, Vikram G; Collart, Martine A (2019). Co-translational assembly of proteasome subunits in NOT1-containing assemblysomes. Nature Structural & Molecular Biology, 26(2):110-120.

Gay, Jamie C; Eckenroth, Brian E; Evans, Chiara M; Langini, Cassiano; Carlson, Samuel; Lloyd, Jonathan T; Caflisch, Amedeo; Glass, Karen C (2019). Disulfide bridge formation influences ligand recognition by the ATAD2 bromodomain. Proteins, 87(2):157-167.

2018

Ehrenmann, Janosch; Schöppe, Jendrik; Klenk, Christoph; Rappas, Mathieu; Kummer, Lutz; Doré, Andrew S; Plückthun, Andreas (2018). High-resolution crystal structure of parathyroid hormone 1 receptor in complex with a peptide agonist. Nature Structural & Molecular Biology, 25(12):1086-1092.

Śledź, Pawel; Caflisch, Amedeo (2018). Protein structure-based drug design: from docking to molecular dynamics. Current Opinion in Structural Biology, 48:93-102.

Dahan, Idit; Sorrentino, Simona; Boujemaa-Paterski, Rajaa; Medalia, Ohad (2018). Tiopronin-Protected Gold Nanoparticles as a Potential Marker for Cryo-EM and Tomography. Structure, 26(10):1408-1413.e3.

Bachas, Costa; Hodzic, Jasmina; van der Mijn, Johannes C; Stoepker, Chantal; Verheul, Henk M W; Wolthuis, Rob M F; Felley-Bosco, Emanuela; van Wieringen, Wessel N; van Beusechem, Victor W; Brakenhoff, Ruud H; de Menezes, Renée X (2018). Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection. BMC Bioinformatics, 19(1):301.

Wu, Yufan; Honegger, Annemarie; Batyuk, Alexander; Mittl, Peer R E; Plückthun, Andreas (2018). Structural Basis for the Selective Inhibition of c-Jun N-Terminal Kinase 1 Determined by Rigid DARPin-DARPin Fusions. Journal of Molecular Biology, 430(14):2128-2138.

Clerici, Marcello; Faini, Marco; Muckenfuss, Lena M; Aebersold, Ruedi; Jinek, Martin (2018). Author Correction: Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex. Nature Structural & Molecular Biology, 25(4):355.

Hansen, Simon; Ernst, Patrick; König, Sebastian L B; Reichen, Christian; Ewald, Christina; Nettels, Daniel; Mittl, Peer R E; Schuler, Benjamin; Plückthun, Andreas (2018). Curvature of designed armadillo repeat proteins allows modular peptide binding. Journal of Structural Biology, 201(2):108-117.

Caflisch, Amedeo; Gianni, Stefano (2018). Editorial overview: Folding and binding: In silico, in vitro and in cellula. Current Opinion in Structural Biology, 48:iv-vii.

Clerici, Marcello; Faini, Marco; Muckenfuss, Lena M; Aebersold, Ruedi; Jinek, Martin (2018). Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex. Nature Structural & Molecular Biology, 25(2):135-138.

Holmstrom, Erik D; Nettels, Daniel; Schuler, Benjamin (2018). Conformational plasticity of hepatitis C virus core protein enables RNA-induced formation of nucleocapsid-like particles. Journal of Molecular Biology, 430(16):2453-2467.

Yao, Ruyu; Huang, Chao; Chen, Xingfu; Yin, Zhongqiong; Fu, Yuping; Li, Lixia; Feng, Bin; Song, Xu; He, Changliang; Yue, Guizhou; Jing, Bo; Lv, Cheng; Su, Gang; Ye, Gang; Zou, Yuanfeng (2018). Two complement fixing pectic polysaccharides from pedicel of Lycium barbarum L. promote cellular antioxidant defense. International journal of biological macromolecules, 112:356-363.

2017

Garcia-Doval, Carmela; Jinek, Martin (2017). Molecular architectures and mechanisms of Class 2 CRISPR-associated nucleases. Current Opinion in Structural Biology, 47:157-166.

Park, Jiyoung; Lee, Youngsook; Martinoia, Enrico; Geisler, Markus (2017). Plant hormone transporters: what we know and what we would like to know. BMC Biology, 15(1):93.

Peña, Cohue; Hurt, Ed; Panse, Vikram Govind (2017). Eukaryotic ribosome assembly, transport and quality control. Nature Structural & Molecular Biology, 24(9):689-699.

Plitzko, Jürgen M; Schuler, Benjamin; Selenko, Philipp (2017). Structural biology outside the box-inside the cell. Current Opinion in Structural Biology, 46:110-121.

Wulf, Marie-Angela; Senatore, Assunta; Aguzzi, Adriano (2017). The biological function of the cellular prion protein: an update. BMC Biology, 15:34.

Zhang, Jie; Hwang, Jae-Ung; Song, Won-Yong; Martinoia, Enrico; Lee, Youngsook (2017). Identification of amino acid residues important for the arsenic resistance function of Arabidopsis ABCC1. FEBS letters, 591(4):656-666.

Hofmann, Ariane L; Behr, Jonas; Singer, Jochen; Kuipers, Jack; Beisel, Christian; Schraml, Peter; Moch, Holger; Beerenwinkel, Niko (2017). Detailed simulation of cancer exome sequencing data reveals differences and common limitations of variant callers. BMC Bioinformatics, 18(1):8.

Ambrosi, Christina; Manzo, Massimiliano; Baubec, Tuncay (2017). Dynamics and context-dependent roles of DNA methylation. Journal of Molecular Biology, 429(10):1459-1475.

Lischer, Heidi E L; Shimizu, Kentaro K (2017). Reference-guided de novo assembly approach improves genome reconstruction for related species. BMC Bioinformatics, 18(1):474.

Münz, Christian (2017). The macroautophagy machinery in endo- and exocytosis. Journal of Molecular Biology, 429(4):473-485.

2016

Becker, Katja; Sander, Peter (2016). Mycobacterium tuberculosis lipoproteins in virulence and immunity - fighting with a double-edged sword. FEBS letters, 590(21):3800-3819.

Schuler, Benjamin; Soranno, Andrea; Hofmann, Hagen; Nettels, Daniel (2016). Single-molecule FRET spectroscopy and the polymer physics of unfolded and intrinsically disordered proteins. Annual review of biophysics, 45:207-231.

Brunner, Janine D; Schenck, Stephan; Dutzler, Raimund (2016). Structural basis for phospholipid scrambling in the TMEM16 family. Current Opinion in Structural Biology, 39:61-70.

Hatakeyama, Masaomi; Opitz, Lennart; Russo, Giancarlo; Qi, Weihong; Schlapbach, Ralph; Rehrauer, Hubert (2016). SUSHI: an exquisite recipe for fully documented, reproducible and reusable NGS data analysis. BMC Bioinformatics, 17(1):228.

Geertsma, Eric R; Chang, Yung-Ning; Shaik, Farooque R; Neldner, Yvonne; Pardon, Els; Steyaert, Jan; Dutzler, Raimund (2016). Corrigendum: Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family. Nature Structural & Molecular Biology, 23(5):462.

Batyuk, Alexander; Wu, Yufan; Honegger, Annemarie; Heberling, Matthew M; Plückthun, Andreas (2016). DARPin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography. Journal of Molecular Biology, 428(8):1574-1588.

Sprouffske, Kathleen; Wagner, Andreas (2016). Growthcurver: an R package for obtaining interpretable metrics from microbial growth curves. BMC Bioinformatics, 17:172.

Schütz, Marco; Batyuk, Alexander; Klenk, Christoph; Kummer, Lutz; de Picciotto, Seymour; Gülbakan, Basri; Wu, Yufan; Newby, Gregory A; Zosel, Franziska; Schöppe, Jendrik; Sedlák, Erik; Mittl, Peer R E; Zenobi, Renato; Wittrup, K Dane; Plückthun, Andreas (2016). Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools. Journal of Molecular Biology, 428(6):1272-1289.

Olieric, Vincent; Weinert, Tobias; Finke, Aaron D; Anders, Carolin; Li, Dianfan; Olieric, Natacha; Borca, Camelia N; Steinmetz, Michel O; Caffrey, Martin; Jinek, Martin; Wang, Meitian (2016). Data-collection strategy for challenging native SAD phasing. Acta Crystallographica. Section D: Structural Biology, 72(Pt 3):421-429.

Tamir, Adi; Sorrentino, Simona; Motahedeh, Sarah; Shai, Ela; Dubrovsky, Anna; Dahan, Idit; Eibauer, Matthias; Studt, Jan-Dirk; Sapra, K Tanuj; Varon, David; Medalia, Ohad (2016). The macromolecular architecture of platelet-derived microparticles. Journal of Structural Biology, 193(3):181-187.

Yamauchi, Yohei; Greber, Urs F (2016). Principles of virus uncoating: cues and the snooker ball. Traffic, 17(6):569-592.

Seifert, David; Di Giallonardo, Francesca; Töpfer, Armin; Singer, Jochen; Schmutz, Stefan; Günthard, Huldrych F; Beerenwinkel, Niko; Metzner, Karin J (2016). A comprehensive analysis of primer IDs to study heterogeneous HIV-1 populations. Journal of Molecular Biology, 428(1):238-250.

Reichen, Christian; Madhurantakam, Chaithanya; Hansen, Simon; Grütter, Markus G; Plückthun, Andreas; Mittl, Peer R E (2016). Structures of designed armadillo-repeat proteins show propagation of inter-repeat interface effects. Acta Crystallographica. Section D: Structural Biology, 72(Pt 1):168-175.

Ochs, Fena; Somyajit, Kumar; Altmeyer, Matthias; Rask, Maj-Britt; Lukas, Jiri; Lukas, Claudia (2016). 53BP1 fosters fidelity of homology-directed DNA repair. Nature Structural & Molecular Biology, 23(8):714-721.

Leone, Sergio; Santoro, Raffaella (2016). Challenges in the analysis of long noncoding RNA functionality. FEBS letters, 590(15):2342-2353.

Reichen, Christian; Hansen, Simon; Forzani, Cristina; Honegger, Annemarie; Fleishman, Sarel J; Zhou, Ting; Parmeggiani, Fabio; Ernst, Patrick; Madhurantakam, Chaithanya; Ewald, Christina; Mittl, Peer R E; Zerbe, Oliver; Baker, David; Caflisch, Amedeo; Plückthun, Andreas (2016). Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition. Journal of Molecular Biology, 428(22):4467-4489.

Hosseini, Sayed-Rzgar; Wagner, Andreas (2016). The potential for non-adaptive origins of evolutionary innovations in central carbon metabolism. BMC Systems Biology, 10:97.

2015

Schuler, Benjamin D; Smith, Janet L (2015). Editorial overview: Biophysical and molecular biological methods: Structure, dynamics, and single molecules. Current Opinion in Structural Biology, 34:iv-vi.

Geertsma, Eric R; Chang, Yung-Ning; Shaik, Farooque R; Neldner, Yvonne; Pardon, Els; Steyaert, Jan; Dutzler, Raimund (2015). Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family. Nature Structural & Molecular Biology, 22(10):803-808.

Tschan, Mario P; Federzoni, Elena A; Haimovici, Aladin; Britschgi, Christian; Moser, Bettina A; Jin, Jing; Reddy, Venkateshwar A; Sheeter, Dennis A; Fischer, Kimberlee M; Sun, Peiqing; Torbett, Bruce E (2015). Human DMTF1β antagonizes DMTF1α regulation of the p14(ARF) tumor suppressor and promotes cellular proliferation. BBA - Biochimica et Biophysica Acta, 1849(9):1198-1208.

Baral, Pravas Kumar; Swayampakula, Mridula; Aguzzi, Adriano; James, Michael N G (2015). X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. Journal of Structural Biology, 192(1):37-47.

Fleishman, Sarel J; Plückthun, Andreas (2015). Editorial overview: Protein design and evolution-new protein architectures, evolutionary fine-tuning and analysis. Current Opinion in Structural Biology, 33:v-vi.

Ewald, Christina; Christen, Martin T; Watson, Randall P; Mihajlovic, Maja; Zhou, Ting; Honegger, Annemarie; Plückthun, Andreas; Caflisch, Amedeo; Zerbe, Oliver (2015). A combined NMR and computational approach to investigate peptide binding to a designed armadillo repeat protein. Journal of Molecular Biology, 427(10):1916-1933.

Brandmann, Tobias; Jinek, Martin (2015). Crystal structure of the C-terminal 2',5'-phosphodiesterase domain of group A rotavirus protein VP3. Proteins, 83(5):997-1002.

Koziol, Klemens L; Johnson, Philip J M; Stucki-Buchli, Brigitte; Waldauer, Steven A; Hamm, Peter (2015). Fast infrared spectroscopy of protein dynamics: advancing sensitivity and selectivity. Current Opinion in Structural Biology, 34:1-6.

Robinson, J A; van der Meijden, B (2015). Synthesis of a polymyxin derivative for photolabeling studies in the gram-negative bacterium Escherichia coli. Journal of Peptide Science, 21(3):231-235.

Marino, Jacopo; Hohl, Michael; Seeger, Markus A; Zerbe, Oliver; Geertsma, Eric (2015). Bicistronic mRNAs to enhance membrane protein overexpression. Journal of Molecular Biology, 427:943-953.

Gay, Max Hans-Peter; Valenta, Tomas; Herr, Patrick; Paratore-Hari, Lisette; Basler, Konrad; Sommer, Lukas (2015). Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation. BMC Biology, 13(24):online.

Agca, Cavit; Boldt, Karsten; Gubler, Andrea; Meneau, Isabelle; Corpet, Armelle; Samardzija, Marijana; Stucki, Manuel; Ueffing, Marius; Grimm, Christian (2015). Expression of leukemia inhibitory factor in Müller glia cells is regulated by a redox-dependent mRNA stability mechanism. BMC Biology, 13(1):30.

Schmid, Marc W; Grob, Stefan; Grossniklaus, Ueli (2015). HiCdat: a fast and easy-to-use Hi-C data analysis tool. BMC Bioinformatics, 16:277.

Zemke, Martina; Draganova, Kalina; Klug, Annika; Schöler, Anne; Zurkirchen, Luis; Gay, Max Hans-Peter; Cheng, Phil; Koseki, Haruhiko; Valenta, Tomas; Schübeler, Dirk; Basler, Konrad; Sommer, Lukas (2015). Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation. BMC Biology, 13:103.

Bach-Gansmo, Fiona Linnea; Weaver, James C; Jensen, Mads Hartmann; Leemreize, Hanna; Mader, Kevin Scott; Stampanoni, Marco; Brüel, Annemarie; Thomsen, Jesper Skovhus; Birkedal, Henrik (2015). Osteocyte lacunar properties in rat cortical bone: Differences between lamellar and central bone. Journal of Structural Biology, 191(1):59-67.

Fracchiolla, Katrina; Cohen, Leah; Arshava, Boris; Poms, Martin; Zerbe, Oliver; Becker, Jeffrey M; Naider, Fred (2015). Structural Characterization of Triple Transmembrane Domain Containing Fragments of a Yeast G Protein-Coupled Receptor in an Organic: Aqueous Environment by Solution-State NMR Spectroscopy. Journal of Peptide Science, 21(3):212-221.

2014

Sakuraba, Yasuhito; Kim, Dami; Kim, Ye-Sol; Hörtensteiner, Stefan; Paek, Nam-Chon (2014). Arabidopsis STAYGREEN-LIKE (SGRL) promotes abiotic stress-induced leaf yellowing during vegetative growth. FEBS letters, 588(21):3830-3837.

Ehrnstorfer, Ines A; Geertsma, Eric R; Pardon, Els; Steyaert, Jan; Dutzler, Raimund (2014). Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport. Nature Structural & Molecular Biology, 21(11):990-996.

Giannattasio, Michele; Zwicky, Katharina; Follonier, Cindy; Foiani, Marco; Lopes, Massimo; Branzei, Dana (2014). Visualization of recombination-mediated damage bypass by template switching. Nature Structural & Molecular Biology, 21(10):884-892.

Payne, Joshua L; Wagner, Andreas (2014). Latent phenotypes pervade gene regulatory circuits. BMC Systems Biology, 8:64.

Barve, Aditya; Hosseini, Sayed-Rzgar; Martin, Olivier C; Wagner, Andreas (2014). Historical contingency and the gradual evolution of metabolic properties in central carbon and genome-scale metabolisms. BMC Systems Biology, 8:48.

Schilling, Johannes; Schöppe, Jendrik; Sauer, Evelyn; Plückthun, Andreas (2014). Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W. Journal of Molecular Biology, 426(12):2346-2362.

Jost, Christian; Plückthun, Andreas (2014). Engineered proteins with desired specificity: DARPins, other alternative scaffolds and bispecific IgGs. Current Opinion in Structural Biology, 27:102-112.

Vitalis, Andreas; Caflisch, Amedeo (2014). Equilibrium sampling approach to the interpretation of electron density maps. Structure, 22(1):156-167.

Schilling, Johannes; Schöppe, Jendrik; Plückthun, Andreas (2014). From DARPins to LoopDARPins: novel LoopDARPin design allows the selection of low picomolar binders in a single round of ribosome display. Journal of Molecular Biology, 426(3):691-721.

Reichen, Christian; Hansen, Simon; Plückthun, Andreas (2014). Modular peptide binding: from a comparison of natural binders to designed armadillo repeat proteins. Journal of Structural Biology, 185(2):147-162.

Rinaldi, Fabio; Clematide, Simon; Marques, Hernani; Ellendorff, Tilia; Rodriguez-Esteban, Raul; Romacker, Martin (2014). OntoGene web services for biomedical text mining. BMC Bioinformatics, 15(Suppl 14):S6.

Sommer, Lukas (2014). Open questions: development of tumor cell heterogeneity and its implications for cancer treatment. BMC Biology, 12:15.

Watson, Randall P; Christen, Martin T; Ewald, Christina; Bumbak, Fabian; Reichen, Christian; Mihajlovic, Maja; Schmidt, Elena; Güntert, Peter; Caflisch, Amedeo; Plückthun, Andreas; Zerbe, Oliver (2014). Spontaneous self-assembly of engineered armadillo repeat protein fragments into a folded structure. Structure, 22(7):985-995.

Bocquet, Nicolas; Bizard, Anna H; Abdulrahman, Wassim; Larsen, Nicolai B; Faty, Mahamadou; Cavadini, Simone; Bunker, Richard D; Kowalczykowski, Stephen C; Cejka, Petr; Hickson, Ian D; Thomä, Nicolas H (2014). Structural and mechanistic insight into Holliday-junction dissolution by Topoisomerase IIIα and RMI1. Nature Structural & Molecular Biology, 21(3):261-268.

Moharana, Kedar; Zabeau, Lennart; Peelman, Frank; Ringler, Philippe; Stahlberg, Henning; Tavernier, Jan; Savvides, Savvas N (2014). Structural and mechanistic paradigm of leptin receptor activation revealed by complexes with wild-type and antagonist leptins. Structure, 22(6):866-877.

Baral, Pravas Kumar; Swayampakula, Mridula; Rout, Manoj Kumar; Kav, Nat N V; Spyracopoulos, Leo; Aguzzi, Adriano; James, Michael N G (2014). Structural basis of prion inhibition by phenothiazine compounds. Structure, 22(2):291-303.

Friedman, Ran; Caflisch, Amedeo (2014). Wild type and mutants of the HET-s(218-289) prion show different flexibility at fibrillar ends: a simulation study. Proteins, 82(3):399-404.

Ramakrishnan, Chandrasekhar; Bieri, Andrej; Sauter, Nora; Roizard, Sophie; Ringler, Philippe; Müller, Shirley A; Goldie, Kenneth N; Enimanev, Kaloyan; Stahlberg, Henning; Rinn, Bernd; Braun, Thomas (2014). openBEB: open biological experiment browser for correlative measurements. BMC Bioinformatics, 15:84.

2013

Robinson, John A (2013). Max Bergmann lecture protein epitope mimetics in the age of structural vaccinology. Journal of Peptide Science, 19(3):127-140.

Janitza, Silke; Strobl, Carolin; Boulesteix, Anne-Laure (2013). An AUC-based permutation variable importance measure for random forests. BMC Bioinformatics, 14:119.

Rehrauer, Hubert; Opitz, Lennart; Tan, Ge; Sieverling, Lina; Schlapbach, Ralph (2013). Blind spots of quantitative RNA-seq: the limits for assessing abundance, differential expression, and isoform switching. BMC Bioinformatics, 14:370.

Scott, Daniel J; Plückthun, Andreas (2013). Direct molecular evolution of detergent-stable G protein-coupled receptors using polymer encapsulated cells. Journal of Molecular Biology, 425(3):662-677.

Steiner, Sandra; Magno, Andrea; Huang, Danzhi; Caflisch, Amedeo (2013). Does bromodomain flexibility influence histone recognition? FEBS letters, 587(14):2158-2163.

Sandler, Inga; Medalia, Ohad; Aharoni, Amir (2013). Experimental analysis of co-evolution within protein complexes: the yeast exosome as a model. Proteins, 81(11):1997-2006.

Follonier, Cindy; Oehler, Judith; Herrador, Raquel; Lopes, Massimo (2013). Friedreich's ataxia-associated GAA repeats induce replication-fork reversal and unusual molecular junctions. Nature Structural & Molecular Biology, 20(4):486-494.

Berti, Matteo; Chaudhuri, Arnab Ray; Thangavel, Saravanabhavan; Gomathinayagam, Shivasankari; Kenig, Sasa; Vujanovic, Marko; Odreman, Federico; Glatter, Timo; Graziano, Simona; Mendoza-Maldonado, Ramiro; Marino, Francesca; Lucic, Bojana; Biasin, Valentina; Gstaiger, Matthias; Aebersold, Ruedi; Sidorova, Julia M; Monnat, Raymond J; Lopes, Massimo; Vindigni, Alessandro (2013). Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. Nature Structural & Molecular Biology, 20(3):347-354.

Geiger, Roger; Luisoni, Stefania; Johnsson, Kai; Greber, Urs F; Helenius, Ari (2013). Investigating endocytic pathways to the endoplasmic reticulum and to the cytosol using SNAP-trap. Traffic, 14(1):36-46.

Rosenthal, Florian; Feijs, Karla L H; Frugier, Emilie; Bonalli, Mario; Forst, Alexandra H; Imhof, Ralph; Winkler, Hans C; Fischer, David; Caflisch, Amedeo; Hassa, Paul O; Lüscher, Bernhard; Hottiger, Michael O (2013). Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases. Nature Structural & Molecular Biology, 20(4):502-507.

Bukowska, Magdalena A; Grütter, Markus G (2013). New concepts and aids to facilitate crystallization. Current Opinion in Structural Biology, 23(3):409-416.

Kemmerling, Simon; Arnold, Stefan A; Bircher, Benjamin A; Sauter, Nora; Escobedo, Carlos; Dernick, Gregor; Hierlemann, Andreas; Stahlberg, Henning; Braun, Thomas (2013). Single-cell lysis for visual analysis by electron microscopy. Journal of Structural Biology, 183(3):467-73.

Schuler, Benjamin; Hofmann, Hagen (2013). Single-molecule spectroscopy of protein folding dynamics - expanding scope and timescales. Current Opinion in Structural Biology, 23(1):36-47.

Schroeder, Thilo; Barandun, Jonas; Flütsch, Andreas; Briand, Christophe; Mittl, Peer R E; Grütter, Markus G (2013). Specific inhibition of caspase-3 by a competitive DARPin: molecular mimicry between native and designed inhibitors. Structure, 21(2):277-289.

Harapin, Jan; Eibauer, Matthias; Medalia, Ohad (2013). Structural analysis of supramolecular assemblies by cryo-electron tomography. Structure, 21(9):1522-1530.

Jost, Christian; Schilling, Johannes; Tamaskovic, Rastislav; Schwill, Martin; Honegger, Annemarie; Plückthun, Andreas (2013). Structural basis for eliciting a cytotoxic effect in HER2-overexpressing cancer cells via binding to the extracellular domain of HER2. Structure, 21(11):1979-1991.

Kassube, Susanne A; Jinek, Martin; Fang, Jie; Tsutakawa, Susan; Nogales, Eva (2013). Structural mimicry in transcription regulation of human RNA polymerase II by the DNA helicase RECQL5. Nature Structural & Molecular Biology, 20(7):892-899.

Kebbel, Fabian; Kurz, Mareike; Arheit, Marcel; Grütter, Markus G; Stahlberg, Henning (2013). Structure and substrate-induced conformational changes of the secondary citrate/Sodium symporter CitS revealed by electron crystallography. Structure, 21(7):1243-1250.

Gigant, Benoît; Wang, Weiyi; Dreier, Birgit; Jiang, Qiyang; Pecqueur, Ludovic; Plückthun, Andreas; Wang, Chunguang; Knossow, Marcel (2013). Structure of a kinesin-tubulin complex and implications for kinesin motility. Nature Structural & Molecular Biology, 20(8):1001-1007.

2012

Gonnet, Pedro; Dimopoulos, Sotiris; Widmer, Lukas; Stelling, Jörg (2012). A specialized ODE integrator for the efficient computation of parameter sensitivities. BMC Systems Biology, 6:46.

Rigort, Alexander; Günther, David; Hegerl, Reiner; Baum, Daniel; Weber, Britta; Prohaska, Steffen; Medalia, Ohad; Baumeister, Wolfgang; Hege, Hans-Christian (2012). Automated segmentation of electron tomograms for a quantitative description of actin filament networks. Journal of Structural Biology, 177(1):135-144.

Merz, Tobias; Heck, Tobias; Geueke, Birgit; Mittl, Peer R E; Briand, Christophe; Seebach, Dieter; Kohler, Hans-Peter E; Grütter, Markus G (2012). Autoproteolytic and Catalytic Mechanisms for the β-Aminopeptidase BapA-A Member of the Ntn Hydrolase Family. Structure, 20(11):1850-1860.

Novinec, Marko; Lenarčič, Brigita; Baici, Antonio (2012). Clusterin is a specific stabilizer and liberator of extracellular cathepsin K. FEBS Letters, 586(7):1062-1066.

Kemmerling, Simon; Ziegler, Jörg; Schweighauser, Gabriel; Arnold, Stefan A; Giss, Dominic; Müller, Shirley A; Ringler, Philippe; Goldie, Kenneth N; Goedecke, Nils; Hierlemann, Andreas; Stahlberg, Henning; Engel, Andreas; Braun, Thomas (2012). Connecting μ-fluidics to electron microscopy. Journal of Structural Biology, 177(1):128-134.

Hohl, Michael; Briand, Christophe; Grütter, Markus G; Seeger, Markus A (2012). Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation. Nature Structural and Molecular Biology, 19(4):395-402.

Varadamsetty, Gautham; Tremmel, Dirk; Hansen, Simon; Parmeggiani, Fabio; Plückthun, Andreas (2012). Designed armadillo repeat proteins: library generation, characterization and selection of Peptide binders with high specificity. Journal of Molecular Biology, 424(1-2):68-87.

Tars, Kaspars; Kotelovica, Svetlana; Lipowsky, Gerd; Bauer, Monika; Beerli, Roger R; Bachmann, Martin F; Maurer, Patrik (2012). Different binding modes of free and carrier-protein-coupled nicotine in a human monoclonal antibody. Journal of Molecular Biology, 415(1):118-127.

Meyer, Andrea; Megerle, Judith A; Kuttler, Christina; Müller, Johannes; Aguilar, Claudio; Eberl, Leo; Hense, Burkhard A; Rädler, Joachim O (2012). Dynamics of AHL mediated quorum sensing under flow and non-flow conditions. Physical Biology, 9(2):026007.

Schaefer, Jonas V; Plückthun, Andreas (2012). Engineering aggregation resistance in IgG by two independent mechanisms: lessons from comparison of Pichia pastoris and mammalian cell expression. Journal of Molecular Biology, 417(4):309-335.

Grossman, Einat; Dahan, Idit; Stick, Reimer; Goldberg, Martin W; Gruenbaum, Yosef; Medalia, Ohad (2012). Filaments assembly of ectopically expressed Caenorhabditis elegans lamin within Xenopus oocytes. Journal of Structural Biology, 177(1):113-118.

Grossman, Einat; Medalia, Ohad; Zwerger, Monika (2012). Functional architecture of the nuclear pore complex. Annual Review of Biophysics, 41:557-584.

Pedersen, S J; Bhatia, V K; Jurt, S; Paulsson, J F; Pedersen, M H; Jorgensen, R; Holst, B; Stamou, D; Vrang, N; Zerbe, O; Jensen, K J (2012). Improving membrane binding as a design strategy for amphipathic peptide hormones: 2-helix variants of PYY3-36. Journal of Peptide Science, 18(9):579-587.

Rennebaum, Sandra; Caflisch, Amedeo (2012). Inhibition of interdomain motion in g-actin by the natural product latrunculin: a molecular dynamics study. Proteins, 80(8):1998-2008.

Kudryashev, Mikhail; Castaño-Díez, Daniel; Stahlberg, Henning (2012). Limiting factors in single particle cryo electron tomography. Computational and Structural Biotechnology Journal, 1(2):online.

Schlinkmann, Karola M; Hillenbrand, Matthias; Rittner, Alexander; Künz, Madeleine; Strohner, Ralf; Plückthun, Andreas (2012). Maximizing Detergent Stability and Functional Expression of a GPCR by Exhaustive Recombination and Evolution. Journal of Molecular Biology, 422(3):414-428.

Rajendran, Lawrence; Annaert, Wim (2012). Membrane trafficking pathways in Alzheimer's disease. Traffic, 13(6):759-770.

Henderson, Richard; Sali, Andrej; Baker, Matthew L; Carragher, Bridget; Devkota, Batsal; Downing, Kenneth H; Egelman, Edward H; Feng, Zukang; Frank, Joachim; Grigorieff, Nikolaus; Jiang, Wen; Ludtke, Steven J; Medalia, Ohad; Penczek, Pawel A; Rosenthal, Peter B; Rossmann, Michael G; Schmid, Michael F; Schröder, Gunnar F; Steven, Alasdair C; Stokes, David L; Westbrook, John D; Wriggers, Willy; Yang, Huanwang; Young, Jasmine; Berman, Helen M; Chiu, Wah; Kleywegt, Gerard J; Lawson, Catherine L (2012). Outcome of the first electron microscopy validation task force meeting. Structure, 20(2):205-214.

Bauer, Chris; Kleinjung, Frank; Rutishauser, Dorothea; Panse, Christian; Chadt, Alexandra; Dreja, Tanja; Al-Hasani, Hadi; Reinert, Knut; Schlapbach, Ralph; Schuchhardt, Johannes (2012). PPINGUIN: Peptide Profiling Guided Identification of Proteins improves quantitation of iTRAQ ratios. BMC Bioinformatics, 13:34.

Steiner, Sandra; Caflisch, Amedeo (2012). Peptide binding to the PDZ3 domain by conformational selection. Proteins, 80(11):2562-2572.

Christen, Barbara; Hornemann, Simone; Damberger, Fred F; Wüthrich, Kurt (2012). Prion Protein mPrP[F175A](121-231): Structure and Stability in Solution. Journal of molecular biology, 423(4):496-502.

Kebbel, Fabian; Kurz, Mareike; Grütter, Markus G; Stahlberg, Henning (2012). Projection structure of the secondary citrate/sodium symporter CitS at 6 Å resolution by electron crystallography. Journal of Molecular Biology, 418(1-2):117-126.

Bokstad, Melanie; Sabanay, Helena; Dahan, Idit; Geiger, Benjamin; Medalia, Ohad (2012). Reconstructing adhesion structures in tissues by cryo-electron tomography of vitrified frozen sections. Journal of Structural Biology, 178(2):76-83.

Jansen, David A W A M; Cant, Michael A; Manser, Marta B (2012). Segmental concatenation of individual signatures and context cues in banded mongoose (Mungos mungo) close calls. BMC Biology, 10:97.

Medalia, Ohad; Frangakis, Achilleas (2012). Special issue on electron tomography. Journal of Structural Biology, 178(2):75.

Bank, Erin M; Ben-Harush, Kfir; Feinstein, Naomi; Medalia, Ohad; Gruenbaum, Yosef (2012). Structural and physiological phenotypes of disease-linked lamin mutations in C. elegans. Journal of Structural Biology, 177(1):106-112.

Baral, Pravas Kumar; Wieland, Barbara; Swayampakula, Mridula; Polymenidou, Magdalini; Rahman, Muhammad Hafiz; Kav, Nat N V; Aguzzi, Adriano; James, Michael N G (2012). Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1. Acta crystallographica. Section D, Biological crystallography, 68(Pt 11):1501-1512.

Maimon, Tal; Elad, Nadav; Dahan, Idit; Medalia, Ohad (2012). The human nuclear pore complex as revealed by cryo-electron tomography. Structure, 20(6):998-1006.

Ali, Ammar A E; Timinszky, Gyula; Arribas-Bosacoma, Raquel; Kozlowski, Marek; Hassa, Paul O; Hassler, Markus; Ladurner, Andreas G; Pearl, Laurence H; Oliver, Antony W (2012). The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks. Nature Structural & Molecular Biology, 19(7):685-692.

Ray Chaudhuri, Arnab; Hashimoto, Yoshitami; Herrador, Raquel; Neelsen, Kai J; Fachinetti, Daniele; Bermejo, Rodrigo; Cocito, Andrea; Costanzo, Vincenzo; Lopes, Massimo (2012). Topoisomerase I poisoning results in PARP-mediated replication fork reversal. Nature Structural and Molecular Biology, 19(4):417-423.

Mokso, R; Quaroni, L; Marone, F; Irvine, S; Vila-Comamala, J; Blanke, A; Stampanoni, M (2012). X-ray mosaic nanotomography of large microorganisms. Journal of Structural Biology, 177(2):233-238.

2011

Schneider, Gerold; Clematide, Simon; Rinaldi, Fabio (2011). Detection of interaction articles and experimental methods in biomedical literature. BMC Bioinformatics, 12(Suppl 8):S13.

Zamora-Sillero, E; Hafner, M; Ibig, A; Stelling, J; Wagner, A (2011). Efficient characterization of high-dimensional parameter spaces for systems biology. BMC Systems Biology, 5:142.

Hottiger, M O (2011). ADP-ribosylation of histones by ARTD1: an additional module of the histone code? FEBS Letters, 585(11):1595-1599.

Sironi, L; Solon, J; Conrad, C; Mayer, T U; Brunner, D; Ellenberg, J (2011). Automatic quantification of microtubule dynamics enables RNAi-screening of new mitotic spindle regulators. Cytoskeleton, 68(5):266-278.

Arighi, C; Roberts, P; Agarwal, S; Bhattacharya, S; Cesareni, G; Chatr-aryamontri, A; Clematide, S; Gaudet, P; Giglio, M; Harrow, I; Huala, E; Krallinger, M; Leser, U; Li, D; Liu, F; Lu, Z; Maltais, L; Okazaki, N; Perfetto, L; Rinaldi, Fabio; Saetre, R; Salgado, D; Srinivasan, P; Thomas, P; Toldo, L; Hirschman, L; Wu, C (2011). BioCreative III interactive task: an overview. BMC Bioinformatics, 12(Suppl 8):S4.

Yahav, T; Maimon, T; Grossman, E; Dahan, I; Medalia, O (2011). Cryo-electron tomography: gaining insight into cellular processes by structural approaches. Current Opinion in Structural Biology, 21(5):670-677.

Baral, P K; Wieland, B; Swayampakula, M; Polymenidou, M; Aguzzi, A; Kav, N N V; James, M N G (2011). Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications, 67(Pt 10):1211-1213.

Stefan, N; Martin-Killias, P; Wyss-Stoeckle, S; Honegger, A; Zangemeister-Wittke, U; Plückthun, A (2011). DARPins recognizing the tumor-associated antigen EpCAM selected by phage and ribosome display and engineered for multivalency. Journal of Molecular Biology, 413(4):826-43.

Ramadan, K; Meerang, M (2011). Degradation-linked ubiquitin signal and proteasome are integral components of DNA double strand break repair: New perspectives for anti-cancer therapy. FEBS Letters, 585(18):2868-2875.

Monroe, N; Sennhauser, G; Seeger, M A; Briand, C; Grütter, M G (2011). Designed ankyrin repeat protein binders for the crystallization of AcrB: Plasticity of the dominant interface. Journal of Structural Biology, 174(2):269-281.

Kakalacheva, K; Lünemann, J D (2011). Environmental triggers of multiple sclerosis. FEBS Letters, 585(23):3724-3729.

Samal, A; Wagner, A; Martin, O C (2011). Environmental versatility promotes modularity in genome-scale metabolic networks. BMC Systems Biology, 5:135.

Dodevski, I; Plückthun, A (2011). Evolution of three human GPCRs for higher expression and stability. Journal of Molecular Biology, 408(4):599-615.

Matias Rodrigues, J F; Wagner, A (2011). Genotype networks, innovation, and robustness in sulfur metabolism. BMC Systems Biology, 5:39.

Dreier, B; Mikheeva, G; Belousova, N; Parizek, P; Boczek, E; Jelesarov, I; Forrer, P; Plückthun, A; Krasnykh, V (2011). Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targeting. Journal of Molecular Biology, 405(2):410-426.

Ganesan, R; Jelakovic, S; Mittl, P R E; Caflisch, A; Grütter, M G (2011). In silico identification and crystal structure validation of caspase-3 inhibitors without a P1 aspartic acid moiety. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications, 67(Pt 8):842-850.

Rigozzi, S; Stemmer, A; Müller, R; Snedeker, J G (2011). Mechanical response of individual collagen fibrils in loaded tendon as measured by atomic force microscopy. Journal of Structural Biology, 176(1):9-15.

Moehle, K; Freund, A; Kubli, E; Robinson, J A (2011). NMR studies of the solution conformation of the sex peptide from Drosophila melanogaster. FEBS Letters, 585(8):1197-1202.

Pollet, Marc; Germann, Corinne; Bernasconi, Marco V (2011). Phylogenetic analyses using molecular markers reveal ecological lineages in Medetera (Diptera: Dolichopodidae). Canadian Entomologist, 143(6):662-673.

Unno, M; Kawasaki, T; Takahara, H; Heizmann, C W; Kizawa, K (2011). Refined crystal structures of human Ca(2+)/Zn(2+)-binding S100A3 protein characterized by two disulfide bridges. Journal of Molecular Biology, 408(3):477-490.

Flórez, Lope A; Gunka, Katrin; Polania, Rafael; Tholen, Stefan; Stülke, Jörg (2011). SPABBATS: A pathway-discovery method based on Boolean satisfiability that facilitates the characterization of suppressor mutants. BMC Systems Biology, 5:5.

Schärer, M A; Eliot, A C; Grütter, M G; Capitani, G (2011). Structural basis for reduced activity of 1-aminocyclopropane-1-carboxylate synthase affected by a mutation linked to andromonoecy. FEBS Letters, 585(1):111-114.

Friedman, R; Caflisch, A (2011). Surfactant effects on amyloid aggregation kinetics. Journal of Molecular Biology, 414(2):303-312.

Ovchinnikova, O Y; Finder, V H; Vodopivec, I; Nitsch, R M; Glockshuber, R (2011). The Osaka FAD mutation E22Δ leads to the formation of a previously unknown type of amyloid β fibrils and modulates Aβ neurotoxicity. Journal of Molecular Biology, 408(4):780-791.

Krallinger, M; Vazquez, M; Leitner, F; Salgado, D; Chatr-aryamontri, A; Winter, A; Perfetto, L; Briganti, L; Licata, L; Iannuccelli, M; Castagnoli, L; Cesareni, G; Tyers, M; Schneider, G; Rinaldi, Fabio; Leaman, R; Gonzalez, G; Matos, S; Kim, S; Wilbur, W; Rocha, L; Shatkay, H; Tendulkar, A; Agarwal, S; Liu, F; Wang, X; Rak, R; Noto, K; Elkan, C; Lu, Z (2011). The Protein-Protein Interaction tasks of BioCreative III: classification/ranking of articles and linking bio-ontology concepts to full text. BMC Bioinformatics, 12(Suppl 8):S3.

Lu, Z; Kao, H Y; Wei, C H; Huang, M; Liu, J; Kuo, C J; Hsu, C N; Tsai, R; Dai, H J; Okazaki, N; Cho, H C; Gerner, M; Solt, I; Agarwal, S; Liu, F; Vishnyakova, D; Ruch, P; Romacker, M; Rinaldi, Fabio; Bhattacharya, S; Srinivasan, P; Liu, H; Torii, M; Matos, S; Campos, D; Verspoor, K; Livingston, K; Wilbur, W (2011). The gene normalization task in BioCreative III. BMC Bioinformatics, 12(Suppl 8):S2.

Markkanen, E; van Loon, B; Ferrari, E; Hübscher, U (2011). Ubiquitylation of DNA polymerase λ. FEBS Letters, 585(18):2826-2830.

Leśniewska, A; Okoniewski, M J (2011). rnaSeqMap: a Bioconductor package for RNA sequencing data exploration. BMC Bioinformatics, 12:200.

2010

Pasquinelli, G; Papadopulos, F; Nigro, M (2010). Nanobacteria and psammoma bodies: ultrastructural observations in a case of pathological placental calcification. Ultrastructural Pathology, 34(6):344-350.

Hashimoto, Y; Chaudhuri, A R; Lopes, Massimo; Costanzo, V (2010). Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis. Nature Structural and Molecular Biology, 17(11):1305-1311.

Wueest, S; Rapold, R A; Schoenle, E J; Konrad, D (2010). Fas activation in adipocytes impairs insulin-stimulated glucose uptake by reducing Akt. FEBS Letters, 584(19):4187-4192.

Briefer, E; Vannoni, E; McElligott, A G (2010). Quality prevails over identity in the sexually selected vocalisations of an ageing mammal. BMC Biology, 8:35.

Huang, D; Caflisch, A (2010). Library screening by fragment-based docking. Journal of Molecular Recognition, 23(2):183-193.

Finder, V H; Vodopivec, I; Nitsch, R M; Glockshuber, R (2010). The Recombinant Amyloid-beta Peptide Abeta1-42 Aggregates Faster and Is More Neurotoxic than Synthetic Abeta1-42. Journal of Molecular Biology, 396(1):9-18.

Schmid, B; Schindelin, J; Cardona, A; Longair, M; Heinsenberg, M (2010). A high-level 3D visualization API for Java and ImageJ. BMC Bioinformatics, 11:274.

Klein, L; Münz, C; Lünemann, J D (2010). Autophagy-mediated antigen processing in CD4(+) T cell tolerance and immunity. FEBS Letters, 584(7):1405-1410.

Helmuth, Jo A; Paul, Grégory; Sbalzarini, Ivo F (2010). Beyond co-localization: inferring spatial interactions between sub-cellular structures from microscopy images. BMC Bioinformatics, 11(1):372.

Schärer, M A; Grütter, M G; Capitani, G (2010). CRK: an evolutionary approach for distinguishing biologically relevant interfaces from crystal contacts. Proteins, 78(12):2707-2713.

Casutt, M S; Wendelspiess, S; Steuber, J; Fritz, G (2010). Crystallization of the Na+-translocating NADH:quinone oxidoreductase from Vibrio cholerae. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications, 66(Pt 12):1677-1679.

Mädler, S; Seitz, M; Robinson, J A; Zenobi, R (2010). Does chemical cross-linking with NHS esters reflect the chemical equilibrium of protein-protein noncovalent interactions in solution? Journal of the American Society for Mass Spectrometry, 21(10):1775-1783.

Misselwitz, B; Strittmatter, G; Periaswamy, B; Schlumberger, M C; Rout, S; Horvath, P; Kozak, K; Hardt, W D (2010). Enhanced CellClassifier: a multi-class classification tool for microscopy images. BMC Bioinformatics, 11:30.

Samal, A; Matias Rodrigues, J F; Jost, J; Martin, O C; Wagner, A (2010). Genotype networks in metabolic reaction spaces. BMC Systems Biology, 4:30.

Raman, S; Fuchs, T J; Wild, P J; Dahl, E; Buhmann, J M; Roth, V (2010). Infinite mixture-of-experts model for sparse survival regression with application to breast cancer. BMC Bioinformatics, 11(Suppl 8):S8.

Vitalis, A; Caflisch, A (2010). Micelle-like architecture of the monomer ensemble of Alzheimer's amyloid-β peptide in aqueous solution and its implications for Aβ aggregation. Journal of Molecular Biology, 403(1):148-165.

Friedman, R; Caflisch, A (2010). On the orientation of the catalytic dyad in aspartic proteases. Proteins, 78(6):1575-1582.

Wetzel, S K; Ewald, C; Settanni, G; Jurt, S; Plückthun, A; Zerbe, O (2010). Residue-resolved stability of full-consensus ankyrin repeat proteins probed by NMR. Journal of Molecular Biology, 402(1):241-258.

Cejka, Petr; Plank, Jody L; Bachrati, Csanad Z; Hickson, Ian D; Kowalczykowski, Stephen C (2010). Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1-Top3. Nature Structural & Molecular Biology, 17(11):1377-1382.

Hilf, R J C; Bertozzi, C; Zimmermann, I; Reiter, A; Trauner, D; Dutzler, R (2010). Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel. Nature Structural and Molecular Biology, 17(11):1330-1336.

Kramer, M A; Wetzel, S K; Plückthun, A; Mittl, P R E; Grütter, M G (2010). Structural determinants for improved stability of designed ankyrin repeat proteins with a redesigned C-capping module. Journal of Molecular Biology, 404(3):381-391.

Bourquin, F; Riezman, H; Capitani, G; Grütter, M G (2010). Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure, 18(8):1054-1065.

Falconer, R J; Penkova, A; Jelesarov, I; Collins, B M (2010). Survey of the year 2008: applications of isothermal titration calorimetry. Journal of Molecular Recognition, 23(5):395-413.

Ebert, A D; Laussmann, M; Wegehingel, S; Kaderali, L; Erfle, H; Reichert, J; Lechner, J; Beer, H D; Pepperkok, R; Nickel, W (2010). Tec-kinase-mediated phosphorylation of fibroblast growth factor 2 is essential for unconventional secretion. Traffic, 11(6):813-86.

Fendt, Sarah-Maria; Sauer, Uwe (2010). Transcriptional regulation of respiration in yeast metabolizing differently repressive carbon substrates. BMC Systems Biology, 4(1):12.

Port, F; Basler, K (2010). Wnt trafficking: new insights into Wnt naturation, secretion and spreading. Traffic, 11(10):1265-1271.

2009

Friedman, R; Pellarin, R; Caflisch, A (2009). Amyloid aggregation on lipid bilayers and its impact on membrane permeability. Journal of Molecular Biology, 387(2):407-415.

Gut, H; Dominici, P; Pilati, S; Astegno, A; Petoukhov, M V; Svergun, D I; Grütter, M G; Capitani, G (2009). A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase. Journal of Molecular Biology, 392(2):334-351.

Hilf, R J; Dutzler, R (2009). A prokaryotic perspective on pentameric ligand-gated ion channel structure. Current Opinion in Structural Biology, 19(4):418-424.

Helmuth, J A; Burckhardt, C J; Greber, U F; Sbalzarini, I F (2009). Shape reconstruction of subcellular structures from live cell fluorescence microscopy images. Journal of Structural Biology, 167(1):1-10.

Pérez-Huerta, A; Cusack, M; McDonald, S; Marone, F; Stampanoni, M; MacKay, S (2009). Brachiopod punctae: A complexity in shell biomineralisation. Journal of Structural Biology, 167(1):62-67.

Interlandi, G (2009). Backbone conformations and side chain flexibility of two somatostatin mimics investigated by molecular dynamics simulations. Proteins, 75(3):659-670.

Ludwig, A; Blume, J; Diep, T M; Yuan, J; Mateos, J M; Leuthäuser, K; Steuble, M; Streit, P; Sonderegger, P (2009). Calsyntenins mediate TGN exit of APP in a Kinesin-1-dependent manner. Traffic, 10(5):572-589.

Dumrese, C; Slomianka, L; Ziegler, U; Choi, S S; Kalia, A; Fulurija, A; Lu, W; Berg, D E; Benghezal, M; Marshall, B; Mittl, P R E (2009). The secreted Helicobacter cysteine-rich protein A causes adherence of human monocytes and differentiation into a macrophage-like phenotype. FEBS Letters, 583(10):1637-1643.

Ratna, P; Scherrer, S; Fleischli, C; Becskei, A (2009). Synergy of repression and silencing gradients along the chromosome. Journal of Molecular Biology, 387(4):826-839.

Peroza, E; Schmucki, Roland; Güntert, P; Freisinger, Eva; Zerbe, Oliver (2009). The βE-domain of wheat Ec-1 metallothionein: a metal-binding domain with a distinctive structure. Journal of Molecular Biology, 387(1):207-218.

Keller, M; Mares, J; Zerbe, O; Grütter, M G (2009). Structural and biochemical studies on procaspase-8: New insights on initiator caspase activation. Structure, 17(3):438-448.

Hamm, P (2009). For Structural Biology, Try Infrared Instead. Structure, 17(2):149-150.

Leemann-Zakaryan, R P; Pahlich, S; Sedda, M; Quero, L; Grossenbacher, D; Gehring, H (2009). Dynamic subcellular localization of the EWS proto-oncoprotein and its association with and stabilization of microtubules. Journal of Molecular Biology, 386(1):1-13.

Touboul, D; Maillard, L; Grässlin, A; Moumne, R; Seitz, M; Robinson, J A; Zenobi, R (2009). How to Deal with Weak Interactions in Noncovalent Complexes Analyzed by Electrospray Mass Spectrometry: Cyclopeptidic Inhibitors of the Nuclear Receptor Coactivator 1-STAT6. Journal of the American Society for Mass Spectrometry, 20(2):303-311.

Zou, C; Kumaran, S; Walser, R; Zerbe, O (2009). Properties of the N-terminal domains from Y receptors probed by NMR spectroscopy. Journal of Peptide Science, 15(3):184-191.

Timinszky, G; Till, S; Hassa, P O; Hothorn, M; Kustatscher, G; Nijmeijer, B; Colombelli, J; Altmeyer, M; Stelzer, E H K; Scheffzek, K; Hottiger, M O; Ladurner, A G (2009). A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nature Structural and Molecular Biology, 16(9):923-929.

Huang, L; Jones, A M E; Searle, I; Patel, K; Vogler, H; Hubner, N C; Baulcombe, D C (2009). An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II. Nature Structural and Molecular Biology, 16(1):91-93.

Jayne, S; Rothgiesser, K M; Hottiger, M O (2009). CARM1 but not its enzymatic activity is required for transcriptional coactivation of NF-kappaB-dependent gene expression. Journal of Molecular Biology, 394(3):485-495.

Nuvolone, M; Aguzzi, A; Heikenwalder, M (2009). Cells and prions: A license to replicate. FEBS Letters, 583(16):2674-2684.

Tegnér, J N; Compte, A; Auffray, C; An, G; Cedersund, G; Clermont, G; Gutkin, B; Oltvai, Z; Stephan, K E; Thomas, R; Villoslada, P (2009). Computational disease modeling - fact or fiction? BMC Systems Biology, 3:56.

Sennhauser, G; Bukowska, M A; Briand, C; Grütter, M G (2009). Crystal structure of the multidrug exporter MexB from Pseudomonas aeruginosa. Journal of Molecular Biology, 389(1):134-145.

Gebäck, T; Koumoutsakos, P (2009). Edge detection in microscopy images using curvelets. BMC bioinformatics, 10:75.

Antonelli, A (2009). Have giant lobelias evolved several times independently? Life form shifts and historical biogeography of the cosmopolitan and highly diverse subfamily Lobelioideae (Campanulaceae). BMC Biology, 7:82.

Jecklin, M C; Schauer, S; Dumelin, C E; Zenobi, R (2009). Label-free determination of protein-ligand binding constants using mass spectrometry and validation using surface plasmon resonance and isothermal titration calorimetry. Journal of Molecular Recognition, 22(4):319-329.

Gannagé, M; Münz, C (2009). Macroautophagy in immunity and tolerance. Traffic, 10(6):615-60.

Christen, B; Hornemann, S; Damberger, F F; Wüthrich, K (2009). Prion protein NMR structure from tammar wallaby (Macropus eugenii) shows that the β2–α2 loop is modulated by long-range sequence effects. Journal of Molecular Biology, 389(5):833-845.

Lapkouski, M; Panjikar, S; Janscak, P; Smatanova, I K; Carey, J; Ettrich, R; Csefalvay, E (2009). Structure of the motor subunit of type I restriction-modification complex EcoR124I. Nature Structural and Molecular Biology, 16(1):94-95.

Weinert, C; Grütter, C; Roschitzki-Voser, H; Mittl, P R E; Grütter, M G (2009). The crystal structure of human pyrin b30.2 domain: implications for mutations associated with familial Mediterranean fever. Journal of Molecular Biology, 394(2):226-236.

Warmuth, S; Zimmermann, I; Dutzler, R (2009). X-ray structure of the C-terminal domain of a prokaryotic cation-chloride cotransporter. Structure, 17(4):538-546.

2008

Jorg, T; Martin, O C; Wagner, A (2008). Neutral network sizes of biological RNA molecules can be computed and are not atypically small. BMC Bioinformatics, 9:464.

Steiner, D; Forrer, P; Plückthun, A (2008). Efficient selection of DARPins with sub-nanomolar affinities using SRP phage display. Journal of Molecular Biology, 382(5):1211-1227.

Gastaldelli, M; Imelli, N; Boucke, K; Amstutz, B; Meier, O; Greber, U F (2008). Infectious Adenovirus Type 2 Transport Through Early but not Late Endosomes. Traffic, 9(12):2265-2278.

Narzi, D; Siu, S W I; Stirnimann, C U; Grimshaw, J P A; Glockshuber, R; Capitani, G; Böckmann, R A (2008). Evidence for proton shuffling in a thioredoxin-like protein during catalysis. Journal of Molecular Biology, 382(4):978-986.

Sennhauser, G; Grütter, M G (2008). Chaperone-assisted crystallography with DARPins. Structure, 16(10):1443-1453.

Vamvaca, K; Jelesarov, J; Hilvert, D (2008). Kinetics and thermodynamics of ligand binding to a molten globular enzyme and its native counterpart. Journal of Molecular Biology, 382(4):971-977.

Bjelic, S; Jelesarov, I (2008). A survey of the year 2007 literature on applications of isothermal titration calorimetry. Journal of Molecular Recognition, 21:289-311.

Jeremic, T; Linden, Anthony; Heimgartner, H (2008). New 21- and 24-atom Aib-containing cyclopeptides. Journal of Peptide Science, 14(9):1051-1061.

Wright, J; Wagner, A (2008). Exhaustive identification of steady state cycles in large stoichiometric networks. BMC Systems Biology, 2:61.

Frey, D; Huber, T; Plückthun, A; Grütter, M G (2008). Structure of the recombinant antibody Fab fragment f3p4. Acta Crystallographica. Section D, Biological Crystallography, 64(Pt 6):636-643.

Wright, J; Wagner, A (2008). The Systems Biology Research Tool: evolvable open-source software. BMC Systems Biology, 2:55.

Kolb, P; Kipouros, C B; Huang, D; Caflisch, A (2008). Structure-based tailoring of compound libraries for high-throughput screening: discovery of novel EphB4 kinase inhibitors. Proteins, 73(1):11-8.

Puorger, C; Eidam, O; Capitani, G; Erilov, D; Grütter, M G; Glockshuber, R (2008). Infinite kinetic stability against dissociation of supramolecular protein complexes through donor strand complementation. Structure, 16(4):631-642.

Hassa, P O; Covic, M; Bedford, M T; Hottiger, M O (2008). Protein arginine methyltransferase 1 coactivates NF-kappaB-dependent gene expression synergistically with CARM1 and PARP1. Journal of Molecular Biology, 377(3):668-678.

Hartmann, C; Chami, M; Zachariae, U; de Groot, B L; Engel, A; Grütter, M G (2008). Vacuolar protein sorting: two different functional states of the AAA-ATPase Vps4p. Journal of Molecular Biology, 377(2):352-363.

Eidam, O; Dworkowski, F S N; Glockshuber, R; Grütter, M G; Capitani, G (2008). Crystal structure of the ternary FimC-FimF(t)-FimD(N) complex indicates conserved pilus chaperone-subunit complex recognition by the usher FimD. FEBS Letters, 582(5):651-655.

Rothe, C; Urlinger, S; Löhning, C; Prassler, J; Stark, Y; Jäger, U; Hubner, B; Bardroff, M; Pradel, I; Boss, M; Bittlingmaier, R; Bataa, T; Frisch, C; Brocks, B; Honegger, A; Urban, M (2008). The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies. Journal of Molecular Biology, 376(4):1182-1200.

Wetzel, S K; Settanni, G; Kenig, M; Binz, H K; Plückthun, A (2008). Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins. Journal of Molecular Biology, 376(1):241-257.

Merz, T; Wetzel, S K; Firbank, S; Plückthun, A; Grütter, M G; Mittl, P R E (2008). Stabilizing ionic interactions in a full-consensus ankyrin repeat protein. Journal of Molecular Biology, 376(1):232-240.

Bjelic, S; Wieninger, S; Jelesarov, I; Karshikoff, A (2008). Electrostatic contribution to the thermodynamic and kinetic stability of the homotrimeric coiled coil Lpp-56: A computational study. Proteins, 70(3):810-822.

Schuler, B; Eaton, W A (2008). Protein folding studied by single-molecule FRET. Current Opinion in Structural Biology, 18(1):16-26.

Interlandi, G; Wetzel, S K; Settanni, G; Plückthun, A; Caflisch, A (2008). Characterization and further stabilization of designed ankyrin repeat proteins by combining molecular dynamics simulations and experiments. Journal of Molecular Biology, 375(3):837-854.

Okhrimenko, O; Jelesarov, I (2008). A survey of the year 2006 literature on applications of isothermal titration calorimetry. Journal of Molecular Recognition, 21(1):1-19.

Brusniak, Mi-Youn; Bodenmiller, Bernd; Campbell, David; Cooke, Kelly; Eddes, James; Garbutt, Andrew; Lau, Hollis; Letarte, Simon; Mueller, Lukas N; Sharma, Vagisha; Vitek, Olga; Zhang, Ning; Aebersold, Ruedi; Watts, Julian D (2008). Corra: Computational framework and tools for LC-MS discovery and targeted mass spectrometry-based proteomics. BMC Bioinformatics, 9:542.

Parmeggiani, F; Pellarin, R; Larsen, A P; Varadamsetty, G; Stumpp, M T; Zerbe, O; Caflisch, A; Plückthun, A (2008). Designed armadillo repeat proteins as general peptide-binding scaffolds: consensus design and computational optimization of the hydrophobic core. Journal of Molecular Biology, 376(5):1282-1304.

Grimshaw, J P A; Stirnimann, C U; Brozzo, M S; Malojcic, G; Grütter, M G; Capitani, G; Glockshuber, R (2008). DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli. Journal of Molecular Biology, 380(4):667-680.

Seeger, M A; von Ballmoos, C; Eicher, T; Brandstätter, L; Verrey, F; Diederichs, K; Pos, K M (2008). Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB. Nature Structural and Molecular Biology, 15(2):199-205.

Pahlich, S; Zakaryan, R; Gehring, H (2008). Identification of proteins interacting with protein arginine methyltransferase 8: The Ewing sarcoma (EWS) protein binds independent of its methylation state. Proteins, 72(4):1125-1137.

Cronin, A; Homburg, S; Dürk, H; Richter, I; Adamska, M; Frère, F; Arand, Michael (2008). Insights into the catalytic mechanism of human sEH phosphatase by site-directed mutagenesis and LC-MS/MS analysis. Journal of Molecular Biology, 383(3):627-640.

Muff, S; Caflisch, A (2008). Kinetic analysis of molecular dynamics simulations reveals changes in the denatured state and switch of folding pathways upon single-point mutation of a beta-sheet miniprotein. Proteins, 70(4):1185-1195.

Fiore, R; Siegel, G; Schratt, G (2008). MicroRNA function in neuronal development, plasticity and disease. Biochimica et Biophysica Acta, 1779(8):471-478.

Schoenauer, R; Lange, S; Hirschy, A; Ehler, E; Perriard, J C; Agarkova, I (2008). Myomesin 3, a novel structural component of the M-band in striated muscle. Journal of Molecular Biology, 376(2):338-351.

Friedman, R; Caflisch, A (2008). Pepsinogen-like activation intermediate of plasmepsin II revealed by molecular dynamics analysis. Proteins, 73(4):814-827.

Gaechter, V; Schraner, E M; Willi, P; Hehl, A B (2008). The single dynamin family protein in the primitive protozoan Giardia lamblia is essential for stage conversion and endocytic transport. Traffic, 9(1):57-71.

Julius, C; Hutter, G; Wagner, U; Seeger, H; Kana, V; Kranich, J; Klöhn, P C; Weissmann, C; Miele, G; Aguzzi, A (2008). Transcriptional stability of cultured cells upon prion infection. Journal of Molecular Biology, 375(5):1222-1233.

2007

Helmuth, J A; Burckhardt, C J; Koumoutsakos, P; Greber, U F; Sbalzarini, I F (2007). A novel supervised trajectory segmentation algorithm identifies distinct types of human adenovirus motion in host cells. Journal of Structural Biology, 159(3):347-358.

Bernasconi, G; Ward, P I; Hellriegel, B (2007). Repeatability of sperm size in outbred and inbred Scathophaga stercoraria (Diptera: Scathophagidae). Canadian Entomologist, 139(2):228-234.

Furrer, E M; Ronchetti, M F; Verrey, F; Pos, K M (2007). Functional characterization of a NapA Na(+)/H(+) antiporter from Thermus thermophilus. FEBS Letters, 581(3):572-578.

Robinson, Mark D; Speed, Terence P (2007). A comparison of Affymetrix gene expression arrays. BMC Bioinformatics, 8:449.

Dutzler, R (2007). A structural perspective on ClC channel and transporter function. FEBS letters, 581(15):2839-44.

Becskei, A; Grusby, M J (2007). Contribution of IL-12R mediated feedback loop to Th1 cell differentiation. FEBS Letters, 581(27):5199-5206.

Wagner, A (2007). From bit to it: How a complex metabolic network transforms information into living matter. BMC Systems Biology, 1:33.

Lombardot, Thierry; Kottmann, Renzo; Giuliani, Gregory; de Bono, Andrea; Addor, Nans; Glöckner, Frank O (2007). MetaLook: a 3D visualisation software for marine ecological genomics. BMC Bioinformatics, 8:406.

Meyer, S; Savaresi, S; Forster, I C; Dutzler, R (2007). Nucleotide recognition by the cytoplasmic domain of the human chloride transporter ClC-5. Nature Structural and Molecular Biology, 14(1):60-7.

Alioth, S; Meyer, S; Dutzler, R; Pervushin, K (2007). The cytoplasmic domain of the chloride channel ClC-0: structural and dynamic characterization of flexible regions. Journal of Molecular Biology, 369(5):1163-1169.

Markovic, S; Dutzler, R (2007). The structure of the cytoplasmic domain of the chloride channel ClC-Ka reveals a conserved interaction interface. Structure, 15(6):715-25.

2006

Camenisch, U; Dip, R; Schumacher, S B; Schuler, B; Naegeli, H (2006). Recognition of helical kinks by xeroderma pigmentosum group A protein triggers DNA excision repair. Nature Structural and Molecular Biology, 13(3):278-284.

Carmona-Saez, P; Pascual-Marqui, R D; Tirado, F; Carazo, J M; Pascual-Montano, A (2006). Biclustering of gene expression data by Non-smooth Non-negative Matrix Factorization. BMC Bioinformatics, 7:78.

Meyer, S; Dutzler, R (2006). Crystal structure of the cytoplasmic domain of the chloride channel ClC-0. Structure, 14(2):299-307.

Accardi, A; Lobet, S; Williams, C; Miller, C J; Dutzler, R (2006). Synergism between halide binding and proton transport in a CLC-type exchanger. Journal of Molecular Biology, 362(4):691-699.

Hägele, S; Behnam, B; Borter, E; Wolfe, J; Paasch, U; Lukashev, D; Sitkovsky, M; Wenger, R H; Katschinski, D M (2006). TSGA10 prevents nuclear localization of the hypoxia-inducible factor (HIF)-1alpha. FEBS Letters, 580(15):3731-3738.

Dutzler, R (2006). The ClC family of chloride channels and transporters. Current Opinion in Structural Biology, 16(4):439-46.

Pascual-Montano, A; Carmona-Saez, P; Chagoyen, M; Tirado, F; Carazo, J M; Pascual-Marqui, R D (2006). bioNMF: a versatile tool for non-negative matrix factorization in biology. BMC Bioinformatics, 7:366.

2005

Friedrich-Heineken, E; Toueille, M; Tännler, B; Bürki, C; Ferrari, E; Hottiger, M O; Hübscher, U (2005). The two DNA clamps Rad9/Rad1/Hus1 complex and proliferating cell nuclear antigen differentially regulate flap endonuclease 1 activity. Journal of Molecular Biology, 353(5):980-989.

Pahlich, S; Bschir, K; Chiavi, C; Belyanskaya, L L; Gehring, H (2005). Different methylation characteristics of protein arginine methyltransferase 1 and 3 toward the Ewing Sarcoma protein and a peptide. Proteins, 61(1):164-175.

Johansson, Patrik; Unge, Torsten; Cronin, Annette; Arand, Michael; Bergfors, Terese; Jones, T Alwyn; Mowbray, Sherry L (2005). Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function. Journal of Molecular Biology, 351(5):1048-1056.

Gavín, R; Braun, N; Nicolas, O; Parra, B; Ureña, J M; Mingorance, A; Soriano, E; Torres, J M; Aguzzi, A; del Río, J A (2005). PrP(106-126) activates neuronal intracellular kinases and Egr1 synthesis through activation of NADPH-oxidase independently of PrPc. FEBS Letters, 579(19):4099-4106.

Henneke, G; Flament, D; Hübscher, U; Querellou, J; Raffin, J P (2005). The hyperthermophilic euryarchaeota Pyrococcus abyssi likely requires the two DNA polymerases D and B for DNA replication. Journal of Molecular Biology, 350(1):53-64.

Röthlisberger, D; Honegger, A; Plückthun, A (2005). Domain interactions in the Fab fragment: a comparative evaluation of the single-chain Fv and Fab format engineered with variable domains of different stability. Journal of Molecular Biology, 347(4):773-789.

Masel, J; Genoud, Nicolas; Aguzzi, A (2005). Efficient inhibition of prion replication by PrP-Fc(2) suggests that the prion is a PrP(Sc) oligomer. Journal of Molecular Biology, 345(5):1243-1251.

Trueb, B; Neuhauss, S C F; Baertschi, S; Rieckmann, T; Schild, C; Taeschler, S (2005). Fish possess multiple copies of fgfrl1, the gene for a novel FGF receptor. Biochimica et Biophysica Acta, 1727(1):65-74.

Lingaraju, G M; Sartori, A A; Kostrewa, D; Prota, A E; Jiricny, J; Winkler, F K (2005). A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure. Structure, 13(1):87-98.

Gaugler, M N M; Tracy, J; Kuhnle, K; Crameri, A; Nitsch, R M; Mohajeri, M H (2005). Modulation of Alzheimer's pathology by cerebro-ventricular grafting of hybridoma cells expressing antibodies against Abeta in vivo. FEBS Letters, 579(3):753-756.

2004

Rojas, A L; Nagem, R A P; Neustroev, K N; Arand, Michael; Adamska, M; Eneyskaya, E V; Kulminskaya, A A; Garratt, R C; Golubev, A M; Polikarpov, I (2004). Crystal structures of beta-galactosidase from Penicillium sp. and its complex with galactose. Journal of Molecular Biology, 343(5):1281-1292.

Lu, M; Kinchen, J M; Rossman, K L; Grimsley, C M; deBakker, C D; Brugnera, E; Tosello-Trampont, A C; Haney, L B; Klingele, D; Sondek, J; Hengartner, M O; Ravichandran, K S (2004). PH domain of ELMO functions in trans to regulate Rac activation via Dock180. Nature Structural and Molecular Biology, 11(8):756-762.

Ramadan, K; Shevelev, I V; Maga, G; Hübscher, U (2004). De novo DNA synthesis by human DNA polymerase lambda, DNA polymerase mu and terminal deoxyribonucleotidyl transferase. Journal of Molecular Biology, 339(2):395-404.

Röthlisberger, D; Pos, K M; Plückthun, A (2004). An antibody library for stabilizing and crystallizing membrane proteins - selecting binders to the citrate carrier CitS. FEBS Letters, 564(3):340-348.

Sigel, Roland K O; Sashital, D G; Abramovitz, D L; Palmer, A G; Butcher, S E; Pyle, A M (2004). Solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motif. Nature Structural and Molecular Biology, 11(2):187-192.

Gehrig, P M; Hunziker, P E; Zahariev, S; Pongor, S (2004). Fragmentation pathways of N(G)-methylated and unmodified arginine residues in peptides studied by ESI-MS/MS and MALDI-MS. Journal of the American Society for Mass Spectrometry, 15(2):142-149.

Mohajeri, M H; Kuehnle, K; Li, H; Poirier, R; Tracy, J; Nitsch, R M (2004). Anti-amyloid activity of neprilysin in plaque-bearing mouse models of Alzheimer's disease. FEBS Letters, 562(1-3):16-21.

Martens, E; Stevens, I; Janssens, V; Vermeesch, J; Götz, J; Goris, J; Van Hoof, C (2004). Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B' regulatory subunits of protein phosphatase 2A in mice. Journal of Molecular Biology, 336(4):971-986.

Dutzler, R (2004). Structural basis for ion conduction and gating in ClC chloride channels. FEBS Letters, 564(3):229-33.

Tzouros, Manuel; Manov, Nikolay; Bienz, Stefan; Bigler, Laurent (2004). Tandem mass spectrometric investigation of acylpolyamines of spider venoms and their 15N-labeled derivatives. Journal of the American Society for Mass Spectrometry, 15(11):1636-1643.

2003

Bergoglio, V; Ferrari, E; Hübscher, U; Cazaux, C; Hoffmann, J S (2003). DNA polymerase beta can incorporate ribonucleotides during DNA synthesis of undamaged and CPD-damaged DNA. Journal of Molecular Biology, 331(5):1017-1023.

Trotman, L C; Achermann, D P; Keller, S; Straub, M; Greber, U F (2003). Non-classical export of an adenovirus structural protein. Traffic, 4(6):390-402.

Janscak, P; Garcia, P L; Hamburger, F; Makuta, Y; Shiraishi, K; Imai, Y; Ikeda, H; Bickle, T A (2003). Characterization and mutational analysis of the RecQ core of the bloom syndrome protein. Journal of Molecular Biology, 330(1):29-42.

Ramadan, K; Maga, G; Shevelev, I V; Villani, G; Blanco, L; Hübscher, U (2003). Human DNA polymerase lambda possesses terminal deoxyribonucleotidyl transferase activity and can elongate RNA primers: implications for novel functions. Journal of Molecular Biology, 328(1):63-72.

Friedrich-Heineken, E; Henneke, G; Ferrari, E; Hübscher, U (2003). The acetylatable lysines of human Fen1 are important for endo- and exonuclease activities. Journal of Molecular Biology, 328(1):73-84.

Greber, U F; Fassati, A (2003). Nuclear import of viral DNA genomes. Traffic, 4(3):136-143.

Freisinger, Eva; Fernandes, Andrea; Grollman, Arthur P; Kisker, Caroline (2003). Crystallographic Characterization of an Exocyclic DNA Adduct: 3,N4-etheno-2′-deoxycytidine in the Dodecamer 5′-CGCGAATTεCGCG-3′. Journal of Molecular Biology, 329(4):685-697.

Peakman, L J; Antognozzi, M; Bickle, T A; Janscak, P; Szczelkun, M D (2003). S-adenosyl methionine prevents promiscuous DNA cleavage by the EcoP1I type III restriction enzyme. Journal of Molecular Biology, 333(2):321-235.

Pradeille, Nicolas; Heimgartner, Heinz (2003). Synthesis of the protected 6–16 segment of Zervamicin II-2, an application of the Azirine/Oxazolone method. Journal of Peptide Science, 9(11-12):827-837.

2002

Henneke, G; Gueguen, Y; Flament, D; Azam, P; Querellou, J; Dietrich, J; Hübscher, U; Raffin, J P (2002). Replication factor C from the hyperthermophilic archaeon Pyrococcus abyssi does not need ATP hydrolysis for clamp-loading and contains a functionally conserved RFC PCNA-binding domain. Journal of Molecular Biology, 323(5):795-810.

Maga, G; Shevelev, I; Ramadan, K; Spadari, S; Hübscher, U (2002). DNA polymerase theta purified from human cells is a high-fidelity enzyme. Journal of Molecular Biology, 319(2):359-369.

Stiehl, D P; Jelkmann, W; Wenger, R H; Hellwig-Bürgel, T (2002). Normoxic induction of the hypoxia-inducible factor 1alpha by insulin and interleukin-1beta involves the phosphatidylinositol 3-kinase pathway. FEBS Letters, 512(1-3):157-162.

Dutzler, R; Schirmer, T; Karplus, M; Fischer, S (2002). Translocation mechanism of long sugar chains across the maltoporin membrane channel. Structure, 10(9):1273-84.

2001

Ziemienowicz, A; Konieczny, I; Hübscher, U (2001). Calf thymus Hsc70 and Hsc40 can substitute for DnaK and DnaJ function in protein renaturation but not in bacteriophage DNA replication. FEBS Letters, 507(1):11-15.

Tasara, T; Maga, G; Hottiger, M O; Hübscher, U (2001). HIV-1 reverse transcriptase and integrase enzymes physically interact and inhibit each other. FEBS Letters, 507(1):39-44.

Briand, C; Kozlov, S V; Sonderegger, P; Grütter, M G (2001). Crystal structure of neuroserpin: a neuronal serpin involved in a conformational disease. FEBS Letters, 505(1):18-22.

Lundstrom, K; Schweitzer, C; Rotmann, D; Hermann, D; Schneider, E M; Ehrengruber, M U (2001). Semliki Forest virus vectors: efficient vehicles for in vitro and in vivo gene delivery. FEBS letters, 504(3):99-103.

Janscak, P; Sandmeier, U; Szczelkun, M D; Bickle, T A (2001). Subunit assembly and mode of DNA cleavage of the type III restriction endonucleases EcoP1I and EcoP15I. Journal of Molecular Biology, 306(3):417-431.

2000

Sigel, Roland K O; Vaidya, A; Pyle, A M (2000). Metal ion binding sites in a group II intron core. Nature Structural Biology, 7(12):1111-6.

Kasper, P; Christen, P; Gehring, H (2000). Empirical calculation of the relative free energies of peptide binding to the molecular chaperone DnaK. Proteins, 40(2):185-192.

Cattori, V; Hagenbuch, B; Hagenbuch, N; Stieger, B; Ha, R; Winterhalter, K E; Meier, P J (2000). Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full-length isoform of the liver-specific transporter-1 (rlst-1) in rat liver. FEBS Letters, 474(2-3):242-245.

Zou, J; Hallberg, B M; Bergfors, T; Oesch, F; Arand, Michael; Mowbray, S L; Jones, T A (2000). Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases. Structure, 8(2):111-22.

Nakano, M Y; Greber, U F (2000). Quantitative microscopy of fluorescent adenovirus entry. Journal of Structural Biology, 129(1):57-68.

Maga, G; Stucki, M; Spadari, S; Hübscher, U (2000). DNA polymerase switching: I. Replication factor C displaces DNA polymerase alpha prior to PCNA loading. Journal of Molecular Biology, 295(4):801.

Mossi, R; Keller, R C; Ferrari, E; Hübscher, U (2000). DNA polymerase switching: II. Replication factor C abrogates primer synthesis by DNA polymerase alpha at a critical length. Journal of Molecular Biology, 295(4):803-814.

Janscak, P; Bickle, T A (2000). DNA supercoiling during ATP-dependent DNA translocation by the type I restriction enzyme EcoAI. Journal of Molecular Biology, 295(4):1089-1099.

Görlach, A; Camenisch, G; Kvietikova, I; Vogt, L; Wenger, R H; Gassmann, M (2000). Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions. Biochimica et Biophysica Acta, 1493(1-2):125-134.

1999

Schell, M J; Letcher, A J; Brearley, C A; Biber, J; Murer, H; Irvine, R F (1999). PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase. FEBS Letters, 461(3):169-172.

Cattori, V; Eckhardt, U; Hagenbuch, B (1999). Molecular cloning and functional characterization of two alternatively spliced Ntcp isoforms from mouse liver1. Biochimica et Biophysica Acta, 1445(1):154-159.

Mullen, R T; Trelease, R N; Duerk, H; Arand, Michael; Hammock, B D; Oesch, F; Grant, D F (1999). Differential subcellular localization of endogenous and transfected soluble epoxide hydrolase in mammalian cells: evidence for isozyme variants. FEBS letters, 445(2-3):301-305.

Maga, G; Jónsson, Z O; Stucki, M; Spadari, S; Hübscher, U (1999). Dual mode of interaction of DNA polymerase epsilon with proliferating cell nuclear antigen in primer binding and DNA synthesis. Journal of Molecular Biology, 285(1):259-267.

Dutzler, R; Rummel, G; Albertí, S; Hernández-Allés, S; Phale, P; Rosenbusch, J; Benedí, V; Schirmer, T (1999). Crystal structure and functional characterization of OmpK36, the osmoporin of Klebsiella pneumoniae. Structure, 7(4):425-34.

Ringhofer, S; Kallen, J; Dutzler, R; Billich, A; Visser, A J; Scholz, D; Steinhauser, O; Schreiber, H; Auer, M; Kungl, A J (1999). X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910: agreement of time-resolved spectroscopy and molecular dynamics simulations. Journal of Molecular Biology, 286(4):1147-59.

1998

Amacker, M; Hübscher, U (1998). Chimeric HIV-1 and feline immunodeficiency virus reverse transcriptases: critical role of the p51 subunit in the structural integrity of heterodimeric lentiviral DNA polymerases. Journal of Molecular Biology, 278(4):757-765.

Proba, K; Gschwend, T P; Sonderegger, P (1998). Cloning and sequencing of the cDNA encoding human neurotrypsin. Biochimica et Biophysica Acta, 1396(2):143-147.

Schurtenberger, P; Egelhaaf, S U; Hindges, R; Maga, G; Jónsson, Z O; May, R P; Glatter, O; Hübscher, U (1998). The solution structure of functionally active human proliferating cell nuclear antigen determined by small-angle neutron scattering. Journal of Molecular Biology, 275(1):123-132.

1997

Maga, G; Amacker, M; Ruel, N; Hübscher, U; Spadari, S (1997). Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions. Journal of Molecular Biology, 274(5):738-747.

Wang, Y F; Dutzler, R; Rizkallah, P J; Rosenbusch, J P; Schirmer, T (1997). Channel specificity: structural basis for sugar discrimination and differential flux rates in maltoporin. Journal of Molecular Biology, 272(1):56-63.

1996

Christen, P; Kasper, P; Gehring, H; Sterk, M (1996). Stereochemical constraint in the evolution of pyridoxal-5'-phosphate-dependent enzymes. A hypothesis. FEBS Letters, 389(1):12-14.

Dutzler, R; Wang, Y F; Rizkallah, P; Rosenbusch, J P; Schirmer, T (1996). Crystal structures of various maltooligosaccharides bound to maltoporin reveal a specific sugar translocation pathway. Structure, 4(2):127-34.

1995

Chapeaurouge, Alexander; Bigler, Laurent; Schäifer, Andrea; Bienz, Stefan (1995). Correlation of stereoselectivity and ion response in electrospray mass-spectrometry. electrospray ionization-mass spectrometry as a tool to predict chemical behavior? Journal of the American Society for Mass Spectrometry, 6(3):207-211.

Brancaccio, A; Schulthess, T; Gesemann, M; Engel, J (1995). Electron microscopic evidence for a mucin-like region in chick muscle alpha-dystroglycan. FEBS Letters, 368(1):139-142.

1994

Arand, Michael; Grant, D F; Beetham, J K; Friedberg, T; Oesch, F; Hammock, B D (1994). Sequence similarity of mammalian epoxide hydrolases to the bacterial haloalkane dehalogenase and other related proteins. Implication for the potential catalytic mechanism of enzymatic epoxide hydrolysis. FEBS letters, 338(3):251-256.

1992

Gebel, T; Arand, Michael; Oesch, F (1992). Induction of the peroxisome proliferator activated receptor by fenofibrate in rat liver. FEBS letters, 309(1):37-40.

1991

Arand, Michael; Knehr, M; Thomas, H; Zeller, H D; Oesch, F (1991). An impaired peroxisomal targeting sequence leading to an unusual bicompartmental distribution of cytosolic epoxide hydrolase. FEBS letters, 294(1-2):19-22.

1986

Berger, E G; Greber, U F; Mosbach, K (1986). Galactosyltransferase-dependent sialylation of complex and endo-N-acetylglucosaminidase H-treated core N-glycans in vitro. FEBS Letters, 203(1):64-68.

This list was generated on Sun May 31 01:32:26 2020 CEST.