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2025

Le Terrier, Christophe; Nordmann, Patrice; Delaval, Adam; Poirel, Laurent; NARA Network; et al; Egli, Adrian; Mancini, Stefano (2025). Potent in vitro activity of sulbactam-durlobactam against NDM-producing Escherichia coli including cefiderocol and aztreonam-avibactam-resistant isolates. Clinical Microbiology and Infection, 31(1):122-124.

2024

Veeraraghavan, Balaji; Walia, Kamini; Egli, Adrian (2024). Re: ‘Introducing new antibiotics for multidrug-resistant bacteria: obstacles and the way forward’ by Tängdén et al. Clinical Microbiology and Infection:Epub ahead of print.

Lu, Nan-Ji; Meier, Philippe; Reina, Giacomo; Aydemir, M Enes; Eitner, Stephanie; Koliwer-Brandl, Hendrik; Egli, Adrian; Kissling, Vera; Wick, Peter; Hafezi, Farhad (2024). Transmission Rates of UV-A and Green Light in an ex vivo Corneal Cross-linking Model for Infectious Keratitis. Journal of cataract and refractive surgery:Epub ahead of print.

Veeraraghavan, Balaji; Walia, Kamini; Egli, Adrian (2024). Re: ‘Potent in-vitro activity of sulbactam-durlobactam against NDM-producing Escherichia coli including cefiderocol and aztreonam-avibactam-resistant isolates’ by Poirel et al. Clinical Microbiology and Infection:Epub ahead of print.

Ott, Chantal; Dutilh, Gilles; Reist, Josiane; Bingisser, Roland; Egli, Adrian; Heininger, Ulrich (2024). Clinical Presentation of Enterovirus D68 in a Swiss Pediatric University Center. The Pediatric Infectious Disease Journal, 43(12):1135-1140.

Purushothaman, Srinithi; Meola, Marco; Roloff, Tim; Rooney, Ashley M; Egli, Adrian (2024). Evaluation of DNA extraction kits for long-read shotgun metagenomics using Oxford Nanopore sequencing for rapid taxonomic and antimicrobial resistance detection. Scientific Reports, 14(1):29531.

Jung, Erik; Griesser, Tizian; Costafrolaz, Jordan; Duverger, Ondine; Mattenberger, Yves; Dittmann, Silvia; Dorst, Andrea; Major, Alexander; Dailler, David; Schäfle, Daniel; Sievers, Susanne; Brodolin, Konstantin; Viollier, Patrick H; Sander, Peter; Gademann, Karl (2024). Switching Residues: A Platform for the Synthesis of Fidaxomicin Antibiotics. Angewandte Chemie Internationale Edition:Epub ahead of print.

Portugal-Calisto, Daniela; Geiger, Alexander Gregor; Rabl, Julius; Vadas, Oscar; Oborská-Oplová, Michaela; Mazur, Jarosław; Richina, Federica; Klingauf-Nerurkar, Purnima; Michel, Erich; Leitner, Alexander; Boehringer, Daniel; Panse, Vikram Govind (2024). An inhibitory segment within G-patch activators tunes Prp43-ATPase activity during ribosome assembly. Nature Communications, 15(1):10150.

Giske, Christian G; Bressan, Michelle; Fiechter, Farah; Hinic, Vladimira; Mancini, Stefano; Nolte, Oliver; Egli, Adrian (2024). GPT-4-based AI agents—the new expert system for detection of antimicrobial resistance mechanisms? Journal of Clinical Microbiology, 62(11):e0068924.

García-Martín, Ana B; Aguilar-Bultet, Lisandra; Gómez-Sanz, Elena; Hug, Monica Alt; Furger, Reto; Eichenberger, Lucas; Schindler, Ruth; Steffen, Ingrid; Egli, Adrian; Stadler, Tanja; Bagutti, Claudia; Tschudin-Sutter, Sarah (2024). Prospective One-Health investigation into low-abundant extended-spectrum β-lactamase producing Enterobacterales enables detection of potential dissemination events and persistence. Science of the Total Environment, 950:175078.

Badinski, Tina; Seiffert, Salome N; Grässli, Fabian; Babouee Flury, Baharak; Besold, Ulrike; Betschon, Elsbeth; Biggel, Michael; Brucher, Angela; Cusini, Alexia; Dörr, Tamara; Egli, Adrian; Goppel, Stephan; Güsewell, Sabine; Keller, Joelle; Von Kietzell, Matthias; Möller, J Carsten; Nolte, Oliver; Ortner, Manuela; Roloff, Tim; Ruetti, Markus; Schlegel, Matthias; Seth-Smith, Helena M B; Stephan, Roger; Stocker, Reto; Vuichard-Gysin, Danielle; Willi, Barbara; Kuster, Stefan P; Kahlert, Christian R; Kohler, Philipp (2024). Colonization with resistant bacteria in hospital employees: an epidemiological surveillance and typing study. Antimicrobial Agents and Chemotherapy, 68(11):e0098524.

Germuskova, Zoja; Sosa, Elisa; Lagos, Amaya Campillay; Aamot, Hege Vangstein; Beale, Mathew A; Bertelli, Claire; Björkmann, Jonas; Couto, Natacha; Feige, Lena; Greub, Gilbert; Hallbäck, Erika Tång; Hodcroft, Emma B; Harmsen, Dag; Jacob, Laurent; Jolley, Keith A; Kahles, André; Mather, Alison E; Neher, Richard A; Neves, Aitana; Niemann, Stefan; Nolte, Oliver; Peacock, Sharon J; Razavi, Mohammad; Roloff, Tim; Schrenzel, Jacques; Sikora, Per; Sundqvist, Martin; Mölling, Paula; Egli, Adrian (2024). Conference report: the first bacterial genome sequencing pan-European network conference. Microbes and infection, 26(8):105410.

Seth-Smith, Helena; Roloff, Tim; Benvenga, Vanni; Egli, Adrian (2024). Usage of Bacterial Whole Genome Sequencing : Outbreaks and Beyond in Pediatric Patients. The Pediatric Infectious Disease Journal:Epub ahead of print.

Dommann, Julian; Kerbl-Knapp, Jakob; Albertos Torres, Diana; Egli, Adrian; Keiser, Jennifer; Schneeberger, Pierre H H (2024). A novel barcoded nanopore sequencing workflow of high-quality, full-length bacterial 16S amplicons for taxonomic annotation of bacterial isolates and complex microbial communities. mSystems, 9(10):e0085924.

Tsang, Kara K; Lam, Margaret M C; Wick, Ryan R; Wyres, Kelly L; Bachman, Michael; Baker, Stephen; Barry, Katherine; Brisse, Sylvain; Campino, Susana; Chiaverini, Alexandra; Cirillo, Daniela Maria; Clark, Taane; Corander, Jukka; Corbella, Marta; Cornacchia, Alessandra; Cuénod, Aline; D'Alterio, Nicola; Di Marco, Federico; Donado-Godoy, Pilar; Egli, Adrian; Farzana, Refath; Feil, Edward J; Fostervold, Aasmund; Gorrie, Claire L; Hassan, Brekhna; Hetland, Marit Andrea Klokkhammer; Hoa, Le Nguyen Minh; Hoi, Le Thi; Howden, Benjamin; Ikhimiukor, Odion O; et al (2024). Diversity, functional classification and genotyping of SHV β-lactamases in Klebsiella pneumoniae. Microbial Genomics, 10(10):001294.

Zingg, Sandra; Kuster, Sabine; von Rotz, Matthias; Portmann, Aurore; Egli, Adrian; Seth-Smith, Helena M B; Schlaepfer, Pascal; Goldenberger, Daniel; Bassetti, Stefano; Marsch, Stephan; Pargger, Hans; Kuehl, Richard; Tschudin-Sutter, Sarah (2024). Outbreak with OXA-23-producing Acinetobacter baumannii in a COVID-19 ICU cohort: unraveling routes of transmission. Antimicrobial Resistance and Infection Control, 13(1):127.

Vock, Isabelle; Aguilar-Bultet, Lisandra; Khanna, Nina; Egli, Adrian; Wehrle-Wieland, Elisabeth; Tamma, Pranita D; Tschudin Sutter, Sarah (2024). Quantifying aminoglycoside resistance in extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales clinical isolates: a retrospective cohort study. Swiss Medical Weekly, 154(10):3904.

Zbinden, Andrea; Seth-Smith, Helena M B; Beltrami, Vanessa; Mancini, Stefano; Droz, Sara; Bürgi, Urs; Melillo, David; Schuurmans, Macé M; Schwizer, Bernhard; Schmid, Iris; Casaulta, Carmen; Barben, Jürg; Mueller, Nicolas J; Imkamp, Frank (2024). Burkholderia cenocepacia ST-250 in cystic fibrosis patients in Switzerland : Genomic investigation of transmission routes. Diagnostic Microbiology and Infectious Disease, 110(2):116429.

Schoch, Otto D; et al; Schulthess, Bettina; Sander, Peter (2024). Tuberkulose in der Schweiz : Leitfaden für Fachpersonen des Gesundheitswesens (revidierte Version Oktober 2024). Köniz: Lungenliga Schweiz (LLS).

Bausch, Severin; Dräger, Sarah; Charitos-Fragkakis, Panteleimon; Egli, Adrian; Moser, Stephan; Hinic, Vladimira; Kuehl, Richard; Bassetti, Stefano; Siegemund, Martin; Rentsch, Katharina M; Hermann, Laura; Schöning, Verena; Hammann, Felix; Sendi, Parham; Osthoff, Michael (2024). Target Attainment and Population Pharmacokinetics of Cefazolin in Patients with Invasive Staphylococcus aureus Infections: A Prospective Cohort Study. Antibiotics, 13(10):928.

Michaelis, Sarah; Gomez-Valero, Laura; Chen, Tong; Schmid, Camille; Buchrieser, Carmen; Hilbi, Hubert (2024). Small molecule communication of Legionella : the ins and outs of autoinducer and nitric oxide signaling. Microbiology and Molecular Biology Reviews, 88(3):e0009723.

Dharuman, Suresh; Phelps, Gregory A; Dunn, Christine M; Wilt, Laura A; Murphy, Patricia A; Lee, Robin B; Snoke, Hannah E; Selchow, Petra; Haldimann, Klara; Böttger, Erik C; Hobbie, Sven N; Sander, Peter; Lee, Richard E (2024). Synthesis and antibacterial action of 3’,6’-disubstituted spectinomycins. The Journal of Antibiotics, 77(9):577-588.

Kuhn, Benedikt T; Zöller, Jonathan; Zimmermann, Iwan; Gemeinhardt, Tim; Özkul, Dogukan H; Langer, Julian D; Seeger, Markus A; Geertsma, Eric R (2024). Interdomain-linkers control conformational transitions in the SLC23 elevator transporter UraA. Nature Communications, 15(1):7518.

Bajka, Anahita; Said, Sadiq; Quiblier, Chantal; Schulthess, Bettina; Reinhold, Ilana; Barthelmes, Daniel; Zweifel, Sandrine Anne; Blaser, Frank (2024). Long-Term Prevalence of Fungal Keratitis at a Swiss Tertiary Eye Clinic. Microorganisms, 12(8):1637.

Mutschler, Eugenio; Roloff, Tim; Neves, Aitana; Vangstein Aamot, Hege; Rodríguez-Sánchez, Belén; Ramirez, Mario; Rossen, John; Couto, Natacha; Novais, Ângela; Howden, Benjamin P; Brisse, Sylvain; Reuter, Sandra; Nolte, Oliver; Egli, Adrian; Seth-Smith, Helena M B (2024). Towards unified reporting of genome sequencing results in clinical microbiology. PeerJ, 12:e17673.

Katic, Ana. Modulation of Mitochondrial Dynamics by the $\textit{Legionella}$ Effector RidL. 2024, University of Zurich, Faculty of Science.

Earp, Jennifer. Structural and Functional Characterization of the Mycobacterial Siderophore Exporter MmpL4. 2024, University of Zurich, Faculty of Science.

Wetzstein, Nils; Diricks, Margo; Anton, Thomas B; Andres, Sönke; Kuhns, Martin; Kohl, Thomas A; Schwarz, Carsten; Lewin, Astrid; Kehrmann, Jan; Kahl, Barbara C; Schmidt, Annika; Zimmermann, Stefan; Jansson, Moritz K; Baron, Sophie A; Schulthess, Bettina; Hogardt, Michael; Friesen, Inna; Niemann, Stefan; Wichelhaus, Thomas A (2024). Clinical and genomic features of Mycobacterium avium complex: a multi-national European study. Genome Medicine, 16(1):86.

Gütlin, Yukino; Albertos Torres, Diana; Gensch, Alexander; Schlotterbeck, Ann-Kathrin; Stöger, Laurent; Heller, Stefanie; Infanti, Laura; Barut, Güliz Tuba; Thiel, Volker; Leuzinger, Karoline; Hirsch, Hans H; Buser, Andreas; Egli, Adrian (2024). Anti-SARS-CoV-2 total immunoglobulin and neutralising antibody responses in healthy blood donors throughout the COVID-19 pandemic: a longitudinal observational study. Swiss Medical Weekly, 154(7):3408.

Fernandez, Javier Eduardo; Egli, Adrian; Overesch, Gudrun; Perreten, Vincent (2024). Time-calibrated phylogenetic and chromosomal mobilome analyses of Staphylococcus aureus CC398 reveal geographical and host-related evolution. Nature Communications, 15(1):5526.

Michaelis, Sarah. Functional Analysis of the $\textit{Legionella pneumophila}$ Nitric Oxide Regulatory Network and its Link to Quorum Sensing. 2024, University of Zurich, Faculty of Science.

Michaelis, Sarah; Chen, Tong; Schmid, Camille; Hilbi, Hubert (2024). Nitric oxide signaling through three receptors regulates virulence, biofilm formation, and phenotypic heterogeneity of Legionella pneumophila. mBio, 15(6):e0071024.

Benz, Fabienne; Camara-Wilpert, Sarah; Russel, Jakob; Wandera, Katharina G; Čepaitė, Rimvydė; Ares-Arroyo, Manuel; Gomes-Filho, José Vicente; Englert, Frank; Kuehn, Johannes A; Gloor, Silvana; Mestre, Mario Rodríguez; Cuénod, Aline; Aguilà-Sans, Mònica; Maccario, Lorrie; Egli, Adrian; Randau, Lennart; Pausch, Patrick; Rocha, Eduardo P C; Beisel, Chase L; Madsen, Jonas Stenløkke; Bikard, David; Hall, Alex R; Sørensen, Søren Johannes; Pinilla-Redondo, Rafael (2024). Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans. Cell Host & Microbe, 32(6):875-886.e9.

Pietrzko, Elisabeth; Bögli, Stefan; Frick, Katja; Ebner-Dietler, Sabeth; Capone, Crescenzo; Imkamp, Frank; Koliwer-Brandl, Hendrik; Müller, Nicolas; Keller, Emanuela; Brandi, Giovanna (2024). Broad Range Eubacterial Polymerase Chain Reaction of Cerebrospinal Fluid Reduces the Time to Exclusion of and Costs Associated with Ventriculostomy-Related Infection in Hemorrhagic Stroke. Neurocritical Care, 40(3):1109-1116.

Kaelin, M B; Wieser, S; Preiswerk, B; Schreiber, P W; Russenberger, D; Kaiser, P; Schulthess, B; Nemeth, J (2024). Mirage de tuberculose in the 21st century. Public Health Action, 14(2):51-55.

Meyer Sauteur, Patrick M; Beeton, Michael L; European Society of Clinical Microbiology and Infectious Disease (2024). Pneumonia outbreaks due to re-emergence of Mycoplasma pneumoniae. The Lancet Microbe, 5(6):e514.

Buettcher, Michael; Egli, Adrian; Albini, Sarah; Altpeter, Ekkehardt; Labutin, Anton; Guidi, Valeria; Tonolla, Mauro; Lienhard, Reto; Opota, Onya; Schmid, Patrizia; Wuethrich, Tsering; Schmidt, Kristina M; TULAR-CH working group (2024). Tularemia on the rise in Switzerland? A one health approach is needed! Infection, 52(3):1165-1169.

Hinic, Vladimira; Seth-Smith, Helena M B; Stammler, Sabrina; Egli, Adrian (2024). Rapid detection of plasmid-mediated AmpC-producers by eazyplex® SuperBug AmpC assay compared to whole-genome sequencing. Journal of Microbiological Methods, 221:106938.

Lerra, Luigi; Panatta, Martina; Bär, Dominik; Zanini, Isabella; Tan, Jennifer Yihong; Pisano, Agnese; Mungo, Chiara; Baroux, Célia; Panse, Vikram Govind; Marques, Ana C; Santoro, Raffaella (2024). An RNA-dependent and phase-separated active subnuclear compartment safeguards repressive chromatin domains. Molecular Cell, 84(9):1667-1683.e10.

Wegner, Fanny; Cabrera-Gil, Blanca; Tanguy, Araud; Beckmann, Christiane; Beerenwinkel, Niko; Bertelli, Claire; Carrara, Matteo; Cerutti, Lorenzo; Chen, Chaoran; Cordey, Samuel; Dumoulin, Alexis; du Plessis, Louis; Friedli, Marc; Gerth, Yannick; Greub, Gilbert; Härri, Adrian; Hirsch, Hans; Howald, Cedric; Huber, Michael; Imhof, Alexander; Kaiser, Laurent; Kufner, Verena; Leib, Stephen L; Leuzinger, Karoline; Lleshi, Etleva; Martinetti, Gladys; Mäusezahl, Mirjam; Neher, Richard; Trkola, Alexandra; Egli, Adrian; et al; SPSP consortium (2024). How much should we sequence? An analysis of the Swiss SARS-CoV-2 surveillance effort. Microbiology Spectrum, 12(5):e0362823.

Boattini, Matteo; Bianco, Gabriele; Llorente, Laura Iglesias; Acero, Laura Alonso; Nunes, Daniel; Seruca, Miguel; Mendes, Vasco Santos; Almeida, André; Bastos, Paulo; Rodríguez-Villodres, Ángel; Gascón, Adelina Gimeno; Halperin, Ana Verónica; Cantón, Rafael; Escartín, Maria Nieves Larrosa; González-López, Juan José; Floch, Pauline; Massip, Clémence; Chainier, Delphine; Barraud, Olivier; Dortet, Laurent; Cuzon, Gaëlle; Zancanaro, Clément; Mizrahi, Assaf; Schade, Rogier; Rasmussen, Asger Nellemann; Schønning, Kristian; Hamprecht, Axel; Schaffarczyk, Lukas; Glöckner, Stefan; Rödel, Jürgen; Kristóf, Katalin; Balonyi, Agnes; Mancini, Stefano; Quiblier, Chantal; et al (2024). Enterobacterales carrying chromosomal AmpC β-lactamases in Europe (EuESCPM): Epidemiology and antimicrobial resistance burden from a cohort of 27 hospitals, 2020-2022. International Journal of Antimicrobial Agents, 63(5):107115.

Gross, Sonja; Herren, Sebastian; Gysin, Marina; Rominski, Anna; Roditscheff, Anna; Risch, Martin; Imkamp, Frank; Crich, David; Hobbie, Sven N (2024). In vitro susceptibility of Neisseria gonorrhoeae to netilmicin and etimicin in comparison to gentamicin and other aminoglycosides. European Journal of Clinical Microbiology & Infectious Diseases, 43(5):821-828.

Jünger, Christian; Imkamp, Frank; Balakrishna, Suraj; Gysin, Marina; Haldimann, Klara; Brugger, Silvio D; Scheier, Thomas C; Hampel, Benjamin; Hobbie, Sven N; Günthard, Huldrych F; Braun, Dominique L (2024). Phenotypic and genotypic characterization of Neisseria gonorrhoeae isolates among individuals at high risk for sexually transmitted diseases in Zurich, Switzerland. International journal of STD & AIDS, 35(6):462-470.

Schreiber, Peter W; Hoessly, Linard D; Boggian, Katia; Neofytos, Dionysios; van Delden, Christian; Egli, Adrian; Dickenmann, Michael; Hirzel, Cédric; Manuel, Oriol; Koller, Michael; Rossi, Simona; Banz, Vanessa; Schmied, Bruno; Guerke, Lorenz; Matter, Maurice; de Rougemont, Olivier; Bonani, Marco; Golshayan, Déla; Schnyder, Aurelia; Sidler, Daniel; Haidar, Fadi; Kuster, Stefan P; Stampf, Susanne; Mueller, Nicolas J; Swiss Transplant Cohort Study (STCS) (2024). Surgical site infections after kidney transplantation are independently associated with graft loss. American Journal of Transplantation, 24(5):795-802.

Erba, Andrea; Franzeck, Fabian C; Hinic, Vladimira; Egli, Adrian; Osthoff, Michael (2024). Utilization of a Meningitis/Encephalitis PCR panel at the University Hospital Basel – a retrospective study to develop a diagnostic decision rule. Frontiers in Medicine, 11:1351903.

Paulowski, Laura; Filip, Roxana; Jankovic Makek, Mateja; Guglielmetti, Lorenzo; Goletti, Delia; van Ingen, Jakko; Kranzer, Katharina; Maurer, Florian P (2024). Impact of the COVID-19 pandemic on the real-world diagnostic infrastructure for tuberculosis—An ESGMYC collaborative study. PLoS ONE, 19(4):e0291404.

Sorgenfrei, Michèle. Nanobody-Mediated Detection and Capture of Gram-Negative Pathogens. 2024, University of Zurich, Faculty of Science.

Findlay, Jacqueline; Raro, Otavio Hallal Ferreira; Poirel, Laurent; Nordmann, Patrice; NARA Network (2024). Molecular analysis of metallo-beta-lactamase-producing Pseudomonas aeruginosa in Switzerland 2022-2023. European Journal of Clinical Microbiology & Infectious Diseases, 43(3):551-557.

Martischang, Romain; Seth-Smith, Helena; Verschuuren, Tess D; Héquet, Delphine; Gaia, Nadia; François, Patrice; Fluit, Ad C; Kluytmans, Jan A J W; Seiffert, Salome N; Tacconelli, Evelina; Cherkaoui, Abdessalam; Harbarth, Stephan; Egli, Adrian; Kohler, Philipp (2024). Regional spread of an atypical ESBL-producing Escherichia coli ST131H89 clone among different human and environmental reservoirs in Western Switzerland. Antimicrobial Agents and Chemotherapy, 68(2):e0092523.

Benvenga, Vanni; Cuénod, Aline; Purushothaman, Srinithi; Dasen, Gottfried; Weisser, Maja; Bassetti, Stefano; Roloff, Tim; Siegemund, Martin; Heininger, Ulrich; Bielicki, Julia; Wehrli, Marianne; Friderich, Paul; Frei, Reno; Widmer, Andreas; Herzog, Kathrin; Fankhauser, Hans; Nolte, Oliver; Bodmer, Thomas; Risch, Martin; Dubuis, Olivier; Pranghofer, Sigrid; Calligaris-Maibach, Romana; Graf, Susanne; Perreten, Vincent; Seth-Smith, Helena M B; Egli, Adrian (2024). Historic methicillin-resistant Staphylococcus aureus: expanding current knowledge using molecular epidemiological characterization of a Swiss legacy collection. Genome Medicine, 16(1):23.

Hilti, Dominique; Wehrli, Faina; Berchtold, Sabine; Bigler, Susanna; Bodmer, Thomas; Seth-Smith, Helena M B; Roloff, Tim; Kohler, Philipp; Kahlert, Christian R; Kaiser, Laurent; Egli, Adrian; Risch, Lorenz; Risch, Martin; Wohlwend, Nadia (2024). S-Gene Target Failure as an Effective Tool for Tracking the Emergence of Dominant SARS-CoV-2 Variants in Switzerland and Liechtenstein, Including Alpha, Delta, and Omicron BA.1, BA.2, and BA.4/BA.5. Microorganisms, 12(2):321.

Søgaard, Kirstine K; Hinic, Vladimira; Goldenberger, Daniel; Gensch, Alexander; Schweitzer, Michael; Bättig, Veronika; Siegemund, Martin; Bassetti, Stefano; Bingisser, Roland; Tamm, Michael; Battegay, Manuel; Weisser, Maja; Stolz, Daiana; Khanna, Nina; Egli, Adrian (2024). Evaluation of the clinical relevance of the Biofire$^{©}$ FilmArray pneumonia panel among hospitalized patients. Infection, 52(1):173-181.

Meyer Sauteur, Patrick M; Beeton, Michael L; European Society of Clinical Microbiology and Infectious Disease (2024). Mycoplasma pneumoniae: delayed re-emergence after COVID-19 pandemic restrictions. The Lancet Microbe, 5(2):e100-e101.

Reinhold, Ilana; Quiblier, Chantal; Blaser, Frank; Bögeholz, Jan; Imkamp, Frank; Schuurmans, Macé M; Soyka, Michael B; Zbinden, Reinhard; Mueller, Nicolas J (2024). Detection of Scedosporium spp.: Colonizer or pathogen? A retrospective analysis of clinical significance and management in a large tertiary centre. Medical Mycology, 62(2):myae002.

Mombelli, Matteo; Neofytos, Dionysios; Huynh-Do, Uyen; Sánchez-Céspedes, Javier; Stampf, Susanne; Golshayan, Dela; Dahdal, Suzan; Stirnimann, Guido; Schnyder, Aurelia; Garzoni, Christian; Venzin, Reto M; Magenta, Lorenzo; Schönenberger, Melanie; Walti, Laura; Hirzel, Cédric; Munting, Aline; Dickenmann, Michael; Koller, Michael; Aubert, John-David; Steiger, Jürg; Pascual, Manuel; Mueller, Thomas F; Schuurmans, Macé; Berger, Christoph; Binet, Isabelle; Villard, Jean; Mueller, Nicolas J; Egli, Adrian; Cordero, Elisa; van Delden, Christian; et al (2024). Immunogenicity of High-Dose vs. MF59-adjuvanted vs. Standard Influenza Vaccine in Solid Organ Transplant Recipients: The STOP-FLU trial. Clinical Infectious Diseases, 78(1):48-56.

Phelps, Gregory A; Cheramie, Martin N; Fernando, Dinesh M; Selchow, Petra; Meyer, Christopher J; Waidyarachchi, Samanthi L; Dharuman, Suresh; Liu, Jiuyu; Meuli, Michael; Molin, Michael Dal; Killam, Benjamin Y; Murphy, Patricia A; Reeve, Stephanie M; Wilt, Laura A; Anderson, Shelby M; Yang, Lei; Lee, Robin B; Temrikar, Zaid H; Lukka, Pradeep B; Meibohm, Bernd; Polikanov, Yury S; Hobbie, Sven N; Böttger, Erik C; Sander, Peter; Lee, Richard E (2024). Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus. Proceedings of the National Academy of Sciences of the United States of America, 121(2):e2314101120.

Botsch, J Josephine; Junker, Roswitha; Sorgenfrei, Michèle; Ogger, Patricia P; Stier, Luca; von Gronau, Susanne; Murray, Peter J; Seeger, Markus A; Schulman, Brenda A; Bräuning, Bastian (2024). Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE. Nature Communications, 15(1):410.

Muigg, Veronika; Seth-Smith, Helena M B; Adam, Kai-Manuel; Weisser, Maja; Hinic, Vladimira; Blaich, Annette; Roloff, Tim; Heininger, Ulrich; Schmid, Hanna; Kohler, Maurus; Graf, Lukas; Winterflood, Dylan M; Schlaepfer, Pascal; Goldenberger, Daniel (2024). Novel Organism Verification and Analysis (NOVA) study: identification of 35 clinical isolates representing potentially novel bacterial taxa using a pipeline based on whole genome sequencing. BMC Microbiology, 24(1):14.

Sollier, Julie; Basler, Marek; Broz, Petr; Dittrich, Petra S; Drescher, Knut; Egli, Adrian; Harms, Alexander; Hierlemann, Andreas; Hiller, Sebastian; King, Carolyn G; McKinney, John D; Moran-Gilad, Jacob; Neher, Richard A; Page, Malcolm G P; Panke, Sven; Persat, Alexandre; Picotti, Paola; Rentsch, Katharina M; Rivera-Fuentes, Pablo; Sauer, Uwe; Stolz, Daiana; Tschudin-Sutter, Sarah; van Delden, Christian; van Nimwegen, Erik; Veening, Jan-Willem; Zampieri, Mattia; Zinkernagel, Annelies S; Khanna, Nina; Bumann, Dirk; Jenal, Urs; et al (2024). Revitalizing antibiotic discovery and development through in vitro modelling of in-patient conditions. Nature Microbiology, 9(1):1-3.

Maffei, Enea; Woischnig, Anne-Kathrin; Burkolter, Marco R; Heyer, Yannik; Humolli, Dorentina; Thürkauf, Nicole; Bock, Thomas; Schmidt, Alexander; Manfredi, Pablo; Egli, Adrian; Khanna, Nina; Jenal, Urs; Harms, Alexander (2024). Phage Paride can kill dormant, antibiotic-tolerant cells of Pseudomonas aeruginosa by direct lytic replication. Nature Communications, 15(1):175.

2023

Jung, Erik; Kraimps, Anastassia; Dittmann, Silvia; Griesser, Tizian; Costafrolaz, Jordan; Mattenberger, Yves; Jurt, Simon; Viollier, Patrick H; Sander, Peter; Sievers, Susanne; Gademann, Karl (2023). Phenolic Substitution in Fidaxomicin: A Semisynthetic Approach to Antibiotic Activity Across Species. Chembiochem, 24(24):e202300570.

Seth-Smith, Helena; Vesenbeckh, Silvan; Egli, Adrian; Ott, Sebastian (2023). SARS-CoV-2 in an immunocompromised host: convalescent plasma therapy and viral evolution elucidated by whole genome sequencing. BMJ Case Reports, 16(12):e255255.

Fan, Mingzhen; Kiefer, Patrick; Charki, Paul; Hedberg, Christian; Seibel, Jürgen; Vorholt, Julia A; Hilbi, Hubert (2023). The Legionella autoinducer LAI-1 is delivered by outer membrane vesicles to promote interbacterial and interkingdom signaling. Journal of Biological Chemistry, 299(12):105376.

Santhosh Kumar, Harshitha; Moore, James; Steiner, Adrian C; Sotirakis, Emmanuel; Schärli, Benjamin; Isnard-Petit, Patricia; Thiam, Kader; Wolfer, David P; Böttger, Erik C (2023). Mistranslation-associated perturbations of proteostasis do not promote accumulation of amyloid beta and plaque deposition in aged mouse brain. Cellular and Molecular Life Sciences, 80(12):378.

Hilti, Dominique; Wehrli, Faina; Roditscheff, Anna; Risch, Martin; Risch, Lorenz; Egli, Adrian; Bodmer, Thomas; Wohlwend, Nadia (2023). SARS-CoV-2 Nucleocapsid Protein Mutations Found in Switzerland Disrupt N-Gene Amplification in Commonly Used Multiplex RT-PCR Assay. Pathogens, 12(12):1383.

Egli, Adrian (2023). ChatGPT, GPT-4, and Other Large Language Models: The Next Revolution for Clinical Microbiology? Clinical Infectious Diseases, 77(9):1322-1328.

Moursy, Ahmed; Cléry, Antoine; Gerhardy, Stefan; Betz, Katharina M; Rao, Sanjana; Mazur, Jarosław; Campagne, Sébastien; Beusch, Irene; Duszczyk, Malgorzata M; Robinson, Mark D; Panse, Vikram Govind; Allain, Frédéric H-T (2023). RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing. Nature Communications, 14(1):7166.

Mancini, Stefano; Seth-Smith, Helena M B; Kolesnik-Goldmann, Natalia; Hinic, Vladimira; Roloff, Tim; Imkamp, Frank; Egli, Adrian (2023). Evaluation of the RESIST ACINETO multiplex immunochromatographic assay for detection of OXA-23-like, OXA-40/58-like and NDM carbapenemase production in Acinetobacter baumannii. Journal of Antimicrobial Chemotherapy, 78(11):2771-2774.

Rudin, Christoph; Bollen, Nena; Hong, Samuel L; Wegner, Fanny; Politi, Lida; Mellou, Kassiani; Geenen, Caspar; Gorissen, Sarah; Verhasselt, Bruno; Durkin, Keith; Henin, Coralie; Logist, Anne-Sophie; Dellicour, Simon; Resa, Tobias; Stadler, Tanja; Maes, Piet; Cuypers, Lize; André, Emmanuel; Egli, Adrian; Baele, Guy (2023). Investigation of an international water polo tournament in Czechia as a potential source for early introduction of the SARS-CoV-2 Omicron variant into Belgium, Switzerland and Germany, November 2021. Eurosurveillance, 28(45):2300018.

Cuénod, Aline; Agnetti, Jessica; Seth-Smith, Helena M B; Roloff, Tim; Wälchli, Denise; Shcherbakov, Dimitri; Akbergenov, Rashid; Tschudin-Sutter, Sarah; Bassetti, Stefano; Siegemund, Martin; Nickel, Christian H; Moran-Gilad, Jacob; Keys, Timothy G; Pflüger, Valentin; Thomson, Nicholas R; Egli, Adrian (2023). Bacterial genome-wide association study substantiates papGII of Escherichia coli as a major risk factor for urosepsis. Genome Medicine, 15(1):89.

Agnetti, Jessica; Büchler, Andrea C; Osthoff, Michael; Helfenstein, Fabrice; Weisser, Maja; Siegemund, Martin; Bassetti, Stefano; Bingisser, Roland; Schaefer, Dirk J; Clauss, Martin; Hinic, Vladimira; Tschudin-Sutter, Sarah; Bättig, Veronika; Khanna, Nina; Egli, Adrian (2023). Identification of microorganisms by a rapid PCR panel from positive blood cultures leads to faster optimal antimicrobial therapy - a before-after study. BMC Infectious Diseases, 23(1):730.

Scheier, T C; Franz, J; Boumasmoud, M; Andreoni, F; Chakrakodi, B; Duvnjak, B; Egli, A; Zingg, W; Ramette, A; Wolfensberger, A; Kouyos, R D; Brugger, S D (2023). Fourier-transform infrared spectroscopy for typing of vancomycin-resistant Enterococcus faecium: performance analysis and outbreak investigation. Microbiology Spectrum, 11(5):e0098423.

Remm, Sille; De Vecchis, Dario; Schöppe, Jendrik; Hutter, Cedric A J; Gonda, Imre; Hohl, Michael; Newstead, Simon; Schäfer, Lars V; Seeger, Markus A (2023). Structural basis for triacylglyceride extraction from mycobacterial inner membrane by MFS transporter Rv1410. Nature Communications, 14(1):6449.

Fischer, Fabienne B; Bigler, Melina; Mäusezahl, Daniel; Hattendorf, Jan; Egli, Adrian; Julian, Timothy R; Rölli, Franziska; Gaia, Valeria; Wymann, Monica; Fridez, Françoise; Bertschi, Stefanie; SwissLEGIO Hospital Network (2023). Legionnaires' disease in Switzerland: rationale and study protocol of a prospective national case-control and molecular source attribution study (SwissLEGIO). Infection, 51(5):1467-1479.

Coste, Alix T; Egli, Adrian; Schrenzel, Jacques; Nickel, Beatrice; Zbinden, Andrea; Lienhard, Reto; Dumoulin, Alexis; Risch, Martin; Greub, Gilbert (2023). IVDR: Analysis of the Social, Economic, and Practical Consequences of the Application of an Ordinance of the In Vitro Diagnostic Ordinance in Switzerland. Diagnostics, 13(18):2910.

Landerl, Alexander; Covaliova, Irina; Ganter, Christoph Camille; Mancini, Stefano; David, Sascha; Andermatt, Rea (2023). Older Adult Woman in a Coma After Acute Laryngitis. Chest, 164(3):e65-e69.

Jana, Santanu; Rajasekaran, Parasuraman; Haldimann, Klara; Vasella, Andrea; Böttger, Erik C; Hobbie, Sven N; Crich, David (2023). Synthesis of Gentamicins C1, C2, and C2a and Antiribosomal and Antibacterial Activity of Gentamicins B1, C1, C1a, C2, C2a, C2b, and X2. ACS Infectious Diseases, 9(8):1622-1633.

Müller, Marius; Wiencierz, Andrea; Gehringer, Christian; Muigg, Veronika; Bassetti, Stefano; Siegemund, Martin; Hinic, Vladimira; Tschudin-Sutter, Sarah; Egli, Adrian (2023). Factors associated with non-carbapenemase mediated carbapenem resistance of Gram-negative bacteria: a retrospective case-control study. International Microbiology, 27(2):597-606.

Hüsler, Dario; Stauffer, Pia; Hilbi, Hubert (2023). Tapping lipid droplets: A rich fat diet of intracellular bacterial pathogens. Molecular Microbiology, 120(2):194-209.

Kolesnik-Goldmann, Natalia; Seth-Smith, Helena M B; Haldimann, Klara; Imkamp, Frank; Roloff, Tim; Zbinden, Reinhard; Hobbie, Sven N; Egli, Adrian; Mancini, Stefano (2023). Comparison of Disk Diffusion, E-Test, and Broth Microdilution Methods for Testing In Vitro Activity of Cefiderocol in Acinetobacter baumannii. Antibiotics, 12(7):1212.

Meile, Susanne; Du, Jiemin; Staubli, Samuel; Grossmann, Sebastian; Koliwer-Brandl, Hendrik; Piffaretti, Pietro; Leitner, Lorenz; Matter, Cassandra I; Baggenstos, Jasmin; Hunold, Laura; Milek, Sonja; Guebeli, Christian; Kozomara-Hocke, Marko; Neumeier, Vera; Botteon, Angela; Klumpp, Jochen; Marschall, Jonas; McCallin, Shawna; Zbinden, Reinhard; Kessler, Thomas M; Loessner, Martin J; Dunne, Matthew; Kilcher, Samuel (2023). Engineered reporter phages for detection of Escherichia coli, Enterococcus, and Klebsiella in urine. Nature Communications, 14(1):4336.

Hammarén, Milka Marjut; Luukinen, Hanna; Sillanpää, Alina; Remans, Kim; Lapouge, Karine; Custódio, Tânia; Löw, Christian; Myllymäki, Henna; Montonen, Toni; Seeger, Markus; Robertson, Joseph; Nyman, Tuula A; Savijoki, Kirsi; Parikka, Mataleena (2023). In vitro and ex vivo proteomics of Mycobacterium marinum biofilms and the development of biofilm-binding synthetic nanobodies. mSystems, 8(3):e0107322.

Imkamp, Frank; Bodendoerfer, Elias; Mancini, Stefano (2023). QUIRMIA-A Phenotype-Based Algorithm for the Inference of Quinolone Resistance Mechanisms in Escherichia coli. Antibiotics, 12(7):1119.

Thomann, Janine; Bryant, Manuel B; Gaertner, Vincent D; Marchesi, Martina; Zbinden, Andrea; Zbinden, Reinhard; Bassler, Dirk; Rüegger, Christoph M (2023). Reliability of the galactomannan enzyme-linked immunoassay in healthy preterm infants: A prospective cohort study. Journal of the Pediatric Infectious Diseases Society, 12(5):306-307.

Hüsler, Dario; Stauffer, Pia; Keller, Bernhard; Böck, Desirée; Steiner, Thomas; Ostrzinski, Anne; Vormittag, Simone; Striednig, Bianca; Swart, A Leoni; Letourneur, François; Maaß, Sandra; Becher, Dörte; Eisenreich, Wolfgang; Pilhofer, Martin; Hilbi, Hubert (2023). The large GTPase Sey1/atlastin mediates lipid droplet- and FadL-dependent intracellular fatty acid metabolism of Legionella pneumophila. eLife, 12:e85142.

Reiber, Claudine; Bodendoerfer, Elias; Brugger, Silvio D; Eberhard, Nadia; Hitz, Eva; Hofmaenner, Daniel A; Herren, Sebastian; Kolesnik-Goldmann, Natalia; Manicini, Stefano; Zbinden, Reinhard; Zinkernagel, Annelies S; Hasse, Barbara (2023). Rapid antimicrobial susceptibility testing in patients with bacteraemia due to Enterobacterales: an implementation study. Swiss Medical Weekly, 153(5):40066.

Neves, Aitana; Walther, Daniel; Martin-Campos, Trinidad; Barbie, Valerie; Bertelli, Claire; Blanc, Dominique; Bouchet, Gérard; Erard, Frédéric; Greub, Gilbert; Hirsch, Hans H; Huber, Michael; Kaiser, Laurent; Leib, Stephen L; Leuzinger, Karoline; Lazarevic, Vladimir; Mäusezahl, Mirjam; Molina, Jorge; Neher, Richard A; Perreten, Vincent; Ramette, Alban; Roloff, Tim; Schrenzel, Jacques; Seth-Smith, Helena M B; Stephan, Roger; Terumalai, Dillenn; Wegner, Fanny; Egli, Adrian (2023). The Swiss Pathogen Surveillance Platform - towards a nation-wide One Health data exchange platform for bacterial, viral and fungal genomics and associated metadata. Microbial Genomics, 9(5):mgen001001.

von Rotz, Matthias; Kuehl, Richard; Durovic, Ana; Zingg, Sandra; Apitz, Anett; Wegner, Fanny; Seth-Smith, Helena M B; Roloff, Tim; Leuzinger, Karoline; Hirsch, Hans H; Kuster, Sabine; Battegay, Manuel; Mariani, Luigi; Schaeren, Stefan; Bassetti, Stefano; Banderet-Uglioni, Florian; Egli, Adrian; Tschudin-Sutter, Sarah (2023). A systematic outbreak investigation of SARS-CoV-2 transmission clusters in a tertiary academic care center. Antimicrobial Resistance and Infection Control, 12(1):38.

Candela, Ana; Guerrero-López, Alejandro; Mateos, Miriam; Gómez-Asenjo, Alicia; Arroyo, Manuel J; Hernandez-García, Marta; Del Campo, Rosa; Cercenado, Emilia; Cuénod, Aline; Méndez, Gema; Mancera, Luis; de Dios Caballero, Juan; Martínez-García, Laura; Gijón, Desirée; Morosini, María Isabel; Ruiz-Garbajosa, Patricia; Egli, Adrian; Cantón, Rafael; Muñoz, Patricia; Rodríguez-Temporal, David; Rodríguez-Sánchez, Belén (2023). Automatic Discrimination of Species within the Enterobacter cloacae Complex Using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and Supervised Algorithms. Journal of Clinical Microbiology, 61(4):e0104922.

Albini, Sarah; Imkamp, Frank; Preiswerk, Benjamin; Borel, Nicole (2023). Chlamydien als Zoonoseerreger. Swiss Medical Forum, 16:46-49.

Biggel, Michael; Johler, Sophia; Roloff, Tim; Tschudin-Sutter, Sarah; Bassetti, Stefano; Siegemund, Martin; Egli, Adrian; Stephan, Roger; Seth-Smith, Helena M B (2023). PorinPredict: In Silico Identification of OprD Loss from WGS Data for Improved Genotype-Phenotype Predictions of P. aeruginosa Carbapenem Resistance. Microbiology Spectrum, 11(2):e0358822.

Mohamad-Ramshan, Rukshana; Ande, Chennaiah; Matsushita, Takahiko; Haldimann, Klara; Vasella, Andrea; Hobbie, Sven N; Crich, David (2023). Synthesis of 4-O-(4-Amino-4-deoxy-β-D-xylopyranosyl)paromomycin and 4-S-(β-D-Xylopyranosyl)-4-deoxy-4'-thio-paromomycin and Evaluation of their Antiribosomal and Antibacterial Activity. Tetrahedron, 135:133330.

Koliwer‐Brandl, Hendrik; Nil, Ahmed; Birri, Jana; Sachs, Maike; Zimmermann, Roland; Zbinden, Reinhard; Balsyte, Dalia (2023). Evaluation of two rapid commercial assays for detection of Streptococcus agalactiae from vaginal samples. Acta Obstetricia et Gynecologica Scandinavica, 102(4):450-456.

Vormittag, Simone; Hüsler, Dario; Haneburger, Ina; Kroniger, Tobias; Anand, Aby; Prantl, Manuel; Barisch, Caroline; Maaß, Sandra; Becher, Dörte; Letourneur, François; Hilbi, Hubert (2023). Legionella- and host-driven lipid flux at LCV-ER membrane contact sites promotes vacuole remodeling. EMBO Reports, 24(3):e56007.

Albini, Sarah; Marti, Hanna; Imkamp, F; Borel, Nicole (2023). Update zum Zoonosepotential von Chlamydien. Schweizer Archiv für Tierheilkunde, 165(3):165-178.

Lu, Nan-Ji; Koliwer-Brandl, Hendrik; Gilardoni, Francesca; Hafezi, Nikki; Knyazer, Boris; Achiron, Asaf; Zbinden, Reinhard; Egli, Adrian; Hafezi, Farhad (2023). The Antibacterial Efficacy of High-Fluence PACK Cross-Linking Can Be Accelerated. Translational vision science & technology, 12(2):12.

Ghielmetti, Giovanni; Seth-Smith, Helena M B; Roloff, Tim; Cernela, Nicole; Biggel, Michael; Stephan, Roger; Egli, Adrian (2023). Whole-genome-based characterization of Campylobacter jejuni from human patients with gastroenteritis collected over an 18 year period reveals increasing prevalence of antimicrobial resistance. Microbial Genomics, 9(2):mgen000941.

Vormittag, Simone; Ende, Rachel J; Derré, Isabelle; Hilbi, Hubert (2023). Pathogen vacuole membrane contact sites – close encounters of the fifth kind. microLife, 4:uqad018.

Pirrone, Michael G; Ande, Chennaiah; Haldimann, Klara; Hobbie, Sven N; Vasella, Andrea; Böttger, Erik C; Crich, David (2023). Importance of Co-operative Hydrogen Bonding in the Apramycin-Ribosomal Decoding A-Site Interaction. ChemMedChem, 18(1):e202200486.

Schreiber, P W; Zihlmann, R; Schärer, Verena; Hasse, Barbara; Imkamp, F; Schulthess, Bettina; Sander, Peter; Zingg, Walter (2023). Longitudinal increase in the detection rate of Mycobacterium chimaera in heater-cooler device-derived water samples. Journal of Hospital Infection, 131:190-193.

Asare, Paul Tetteh; Lee, Chi-Hsien; Hürlimann, Vera; Teo, Youzheng; Cuénod, Aline; Akduman, Nermin; Gekeler, Cordula; Afrizal, Afrizal; Corthesy, Myriam; Kohout, Claire; Thomas, Vincent; de Wouters, Tomas; Greub, Gilbert; Clavel, Thomas; Pamer, Eric G; Egli, Adrian; Maier, Lisa; Vonaesch, Pascale (2023). A MALDI-TOF MS library for rapid identification of human commensal gut bacteria from the class Clostridia. Frontiers in Microbiology, 14:1104707.

Romann, Lucas; Werlen, Laura; Rommers, Nikki; Hermann, Anja; Gisler, Isabelle; Bassetti, Stefano; Bingisser, Roland; Siegemund, Martin; Roloff, Tim; Weisser, Maja; Muigg, Veronika; Hinic, Vladimira; Osthoff, Michael; Franzeck, Fabian C; Egli, Adrian (2023). Factors impacting the pre-analytical quality of blood cultures-Analysis at a tertiary medical center. PLoS ONE, 18(3):e0282918.

Welin, Amanda; Hüsler, Dario; Hilbi, Hubert (2023). Imaging Flow Cytometry of Legionella-Containing Vacuoles in Intact and Homogenized Wild-Type and Mutant Dictyostelium. In: Barteneva, Natasha; Vorobjev, Ivan. Spectral and Imaging Cytometry : Methods and Protocols. New York: Springer, 63-85.

Babouee Flury, Baharak; Bösch, Anja; Gisler, Valentin; Egli, Adrian; Seiffert, Salome N; Nolte, Oliver; Findlay, Jacqueline (2023). Multifactorial resistance mechanisms associated with resistance to ceftazidime-avibactam in clinical Pseudomonas aeruginosa isolates from Switzerland. Frontiers in Cellular and Infection Microbiology, 13:1098944.

Gómez-Sanz, Elena; Bagutti, Claudia; Roth, Jan A; Alt Hug, Monica; García-Martín, Ana B; Maurer Pekerman, Laura; Schindler, Ruth; Furger, Reto; Eichenberger, Lucas; Steffen, Ingrid; Egli, Adrian; Hübner, Philipp; Stadler, Tanja; Aguilar-Bultet, Lisandra; Tschudin-Sutter, Sarah (2023). Spatiotemporal dissemination of ESBL-producing Enterobacterales in municipal sewer systems: a prospective, longitudinal study in the city of Basel, Switzerland. Frontiers in Microbiology, 14:1174336.

2022

Lubriks, Dmitrijs; Haldimann, Klara; Hobbie, Sven N; Vasella, Andrea; Suna, Edgars; Crich, David (2022). Synthesis, Antibacterial and Antiribosomal Activity of the 3C-Aminoalkyl Modification in the Ribofuranosyl Ring of Apralogs (5-O-Ribofuranosyl Apramycins). Antibiotics, 12(1):25.

Dähler, Roman; Brugger, Silvio D; Frank, Michelle; Greutmann, Matthias; Sromicki, Juri; Marques-Maggio, Ewerton; Imkamp, Frank; Bauernschmitt, Robert; Carrel, Thierry; Zinkernagel, Annelies S; Hasse, Barbara (2022). A retrospective analysis of blood culture-negative endocarditis at a tertiary care centre in Switzerland. Swiss Medical Weekly, 152:40012.

Rast, Dimitri; Evers, Katrina Suzanne; Egli, Adrian; Rudin, Christoph; Goischke, Alexandra; Ritz, Nicole (2022). Aerococcus urinae - significance of detection in the paediatric urinary tract: a case series. European Journal of Pediatrics, 182(2):749-756.

Lorè, Nicola Ivan; Saliu, Fabio; Spitaleri, Andrea; Schäfle, Daniel; Nicola, Francesca; Cirillo, Daniela Maria; Sander, Peter (2022). The aminoglycoside-modifying enzyme Eis2 represents a new potential in vivo target for reducing antimicrobial drug resistance in Mycobacterium abscessus complex. European Respiratory Journal, 60(6):2201541.

Piezzi, Vanja; Wassilew, Nasstasja; Atkinson, Andrew; D'Incau, Stéphanie; Kaspar, Tanja; Seth-Smith, Helena Mb; Casanova, Carlo; Bittel, Pascal; Jent, Philipp; Sommerstein, Rami; Buetti, Niccolò; Marschall, Jonas (2022). Nosocomial outbreak of vancomycin-resistant Enterococcus faecium (VRE) ST796, Switzerland, 2017 to 2020. Eurosurveillance, 27(48):2200285.

Waldeck, Frederike; Seiffert, Salome N; Manser, Susanne; Zemp, Danuta; Walt, Angela; Berger, Christoph; Albrich, Werner C; Schlegel, Matthias; Roloff, Tim; Egli, Adrian; Nolte, Oliver; Kahlert, Christian R (2022). Outbreak investigation including molecular characterization of community associated methicillin-resistant Staphylococcus aureus in a primary and secondary school in Eastern Switzerland. Scientific Reports, 12:19826.

Huber, François; Lang, Hans Peter; Heller, Stefanie; Bielicki, Julia Anna; Gerber, Christoph; Meyer, Ernst; Egli, Adrian (2022). Rapid Bacteria Detection from Patients' Blood Bypassing Classical Bacterial Culturing. Biosensors, 12(11):994.

Galazzo, Laura; Meier, Gianmarco; Januliene, Dovile; Parey, Kristian; De Vecchis, Dario; Striednig, Bianca; Hilbi, Hubert; Schäfer, Lars V; Kuprov, Ilya; Moeller, Arne; Bordignon, Enrica; Seeger, Markus A (2022). The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells. Science Advances, 8(41):eabn6845.

Gysin, Marina; Hon, Pei Yun; Tan, Pisey; Sengduangphachanh, Amphonesavanh; Simmalavong, Manivone; Hinfonthong, Pattaraporn; Kaewphanderm, Napaporn; Pham, Thai Duy; Nguyen, Thanh Ha; Haldimann, Klara; Becker, Katja; van Doorn, H Rogier; Hopkins, Jill; Simpson, Andrew J H; Ashley, Elizabeth A; Kesteman, Thomas; Tran, Hoang Huy; Vasoo, Shawn; Ling, Clare L; Roberts, Tamalee; Turner, Paul; Hobbie, Sven N (2022). Apramycin susceptibility of multidrug-resistant Gram-negative blood culture isolates in five countries in South-East Asia. International Journal of Antimicrobial Agents, 60(4):106659.

Aranzana-Climent, Vincent; Hughes, Diarmaid; Cao, Sha; Tomczak, Magdalena; Urbas, Malgorzata; Zabicka, Dorota; Lundberg, Carina Vingsbo; Hansen, Jon; Lindberg, Johan; Hobbie, Sven N; Friberg, Lena E (2022). Translational in vitro and in vivo PKPD modelling for apramycin against Gram-negative lung pathogens to facilitate prediction of human efficacious dose in pneumonia. Clinical Microbiology and Infection, 28(10):1367-1374.

Marchesi, Martina; Zbinden, Andrea (2022). Lyme-Borreliose : Labor Diagnostik. Therapeutische Umschau. Revue thérapeutique, 79(9):448-453.

Zhao, Chenyan; Chirkova, Anna; Rosenborg, Staffan; Palma Villar, Rodrigo; Lindberg, Johan; Hobbie, Sven N; Friberg, Lena E (2022). Population pharmacokinetics of apramycin from first-in-human plasma and urine data to support prediction of efficacious dose. Journal of Antimicrobial Chemotherapy, 77(10):2718-2728.

Brilkova, Margarita; Nigri, Martina; Kumar, Harshitha Santhosh; Moore, James; Mantovani, Matilde; Keller, Claudia; Grimm, Amandine; Eckert, Anne; Shcherbakov, Dimitri; Akbergenov, Rashid; Seebeck, Petra; Krämer, Stefanie D; Wolfer, David P; Gent, Thomas C; Böttger, Erik C (2022). Error-prone protein synthesis recapitulates early symptoms of Alzheimer disease in aging mice. Cell Reports, 40(13):111433.

Purushothaman, Srinithi; Meola, Marco; Egli, Adrian (2022). Combination of Whole Genome Sequencing and Metagenomics for Microbiological Diagnostics. International Journal of Molecular Sciences, 23(17):9834.

Sorgenfrei, Michèle; Hürlimann, Lea M; Remy, Mélissa M; Keller, Peter M; Seeger, Markus A (2022). Biomolecules capturing live bacteria from clinical samples. Trends in Biochemical Sciences, 47(8):673-688.

Hochstrasser, Ramon; Michaelis, Sarah; Brülisauer, Sabrina; Sura, Thomas; Fan, Mingzhen; Maaß, Sandra; Becher, Dörte; Hilbi, Hubert (2022). Migration of Acanthamoeba through Legionella biofilms is regulated by the bacterial Lqs-LvbR network, effector proteins and the flagellum. Environmental Microbiology, 24(8):3672-3692.

Oborská-Oplová, Michaela; Gerhardy, Stefan; Panse, Vikram Govind (2022). Orchestrating ribosomal RNA folding during ribosome assembly. BioEssays, 44(8):e2200066.

Mantovani, Matilde. Mitochondrial sequestration of misfolded proteins and silencing of ER/UPR in response to ribosomal mistranslation. 2022, University of Zurich, Faculty of Science.

Quirke, Jonathan C K; Sati, Girish C; Sonousi, Amr; Gysin, Marina; Haldimann, Klara; Böttger, Erik C; Vasella, Andrea; Hobbie, Sven N; Crich, David (2022). Structure-Activity Relationships for 5'' Modifications of 4,5-Aminoglycoside Antibiotics. ChemMedChem, 17(13):e202200120.

Lange, Christoph; Böttger, Erik C; Cambau, Emmanuelle; Griffith, David E; Guglielmetti, Lorenzo; van Ingen, Jakko; Knight, Shandra L; Marras, Theodore K; Olivier, Kenneth N; Santin, Miguel; Stout, Jason E; Tortoli, Enrico; Wagner, Dirk; Winthrop, Kevin; Daley, Charles L (2022). Consensus management recommendations for less common non-tuberculous mycobacterial pulmonary diseases. Lancet Infectious Diseases, 22(7):e178-e190.

Plattner, Michel; Goyet, Chloé; Haldimann, Klara; Gysin, Marina; Juhas, Mario; Becker, Katja; Hobbie, Sven N (2022). Genotypic and phenotypic analyses of aac(3) aminoglycoside-resistance gene diversity point to three distinct phenotypes of contemporary clinical relevance. Journal of Global Antimicrobial Resistance, 29:534-536.

Walter, Justin D; Remm, Sille; Seeger, Markus A (2022). Fatty acid transporter MFSD2A is a multifunctional gatekeeper in brain and placenta. Nature Structural & Molecular Biology, 29(6):504-506.

Bächli, Patrik; Baars, Sibylle; Simmler, Anita; Zbinden, Reinhard; Schulthess, Bettina (2022). Impact of MALDI-TOF MS identification on anaerobic species and genus diversity in routine diagnostics. Anaerobe, 75:102554.

Moore, James. Proteostatic responses in mammals with a heightened level of error-prone translation. 2022, University of Zurich, Faculty of Science.

Schulthess, Bettina; Akdoğan Kittana, Fatma Nur; Hömke, Rico; Sander, Peter (2022). In Vitro Bedaquiline and Clofazimine Susceptibility Testing in Mycobacterium abscessus. Antimicrobial Agents and Chemotherapy, 66(5):e0234621.

Koch, Philippe; Schmitt, Steven; Heynisch, Alexander; Gumpinger, Anja; Wüthrich, Irene; Gysin, Marina; Shcherbakov, Dimitri; Hobbie, Sven N; Panke, Sven; Held, Martin (2022). Optimization of the antimicrobial peptide Bac7 by deep mutational scanning. BMC Biology, 20:114.

Tharra, Prabhakara R; Mikhaylov, Andrey A; Švejkar, Jiří; Gysin, Marina; Hobbie, Sven N; Švenda, Jakub (2022). Short Synthesis of (+)-Actinobolin: Simple Entry to Complex Small-Molecule Inhibitors of Protein Synthesis. Angewandte Chemie Internationale Edition, 61(17):e202116520.

Juskeviciene, Reda; Fritz, Ann-Kristina; Brilkova, Margarita; Akbergenov, Rashid; Schmitt, Karen; Rehrauer, Hubert; Laczko, Endre; Isnard-Petit, Patricia; Thiam, Kader; Eckert, Anne; Schacht, Jochen; Wolfer, David P; Böttger, Erik C; Shcherbakov, Dimitri (2022). Phenotype of Mrps5-Associated Phylogenetic Polymorphisms Is Intimately Linked to Mitoribosomal Misreading. International Journal of Molecular Sciences, 23(8):4384.

Antimycobacterial Susceptibility Testing Group (2022). Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment. European Respiratory Journal, 59(4):2200166.

Striednig, Bianca; Hilbi, Hubert (2022). Bacterial quorum sensing and phenotypic heterogeneity: how the collective shapes the individual. Trends in Microbiology, 30(4):379-389.

Walker, Timothy M; Miotto, Paolo; Köser, Claudio U; Fowler, Philip W; Knaggs, Jeff; Iqbal, Zamin; Hunt, Martin; Chindelevitch, Leonid; Farhat, Maha R; Cirillo, Daniela Maria; Comas, Iñaki; Posey, James; Omar, Shaheed V; Peto, Timothy Ea; Suresh, Anita; Uplekar, Swapna; Laurent, Sacha; Colman, Rebecca E; Nathanson, Carl-Michael; Zignol, Matteo; Walker, Ann Sarah; CRyPTIC Consortium; Seq&Treat Consortium; Crook, Derrick W; Ismail, Nazir; Rodwell, Timothy C (2022). The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: A genotypic analysis. The Lancet Microbe, 3(4):e265-e273.

Hochstrasser, Ramon; Hilbi, Hubert (2022). The Legionella Lqs-LvbR Regulatory Network Controls Temperature-Dependent Growth Onset and Bacterial Cell Density. Applied and Environmental Microbiology, 88(5):e0237021.

Shcherbakov, Dimitri; Nigri, Martina; Akbergenov, Rashid; Brilkova, Margarita; Mantovani, Matilde; Petit, Patricia Isnard; Grimm, Amandine; Karol, Agnieszka A; Teo, Youjin; Sanchón, Adrián Cortés; Kumar, Yadhu; Eckert, Anne; Thiam, Kader; Seebeck, Petra; Wolfer, David P; Böttger, Erik C (2022). Premature aging in mice with error-prone protein synthesis. Science Advances, 8(9):eabl9051.

Viéitez, Cristina; Busby, Bede P; Ochoa, David; Mateus, André; Memon, Danish; Galardini, Marco; Yildiz, Umut; Trovato, Matteo; Jawed, Areeb; Geiger, Alexander G; Oborská-Oplová, Michaela; Potel, Clement M; Vonesch, Sibylle C; Szu Tu, Chelsea; Shahraz, Mohammed; Stein, Frank; Steinmetz, Lars M; Panse, Vikram G; Noh, Kyung-Min; Savitski, Mikhail M; Typas, Athanasios; Beltrao, Pedro (2022). High-throughput functional characterization of protein phosphorylation sites in yeast. Nature Biotechnology, 40(3):382-390.

Osinnii, Ivan. The effects of mistranslation on proteostatic mechanisms in eukaryotic cells. 2022, University of Zurich, Faculty of Science.

Selchow, Petra; Ordway, Diane J; Verma, Deepshikha; Whittel, Nicholas; Petrig, Aline; Hobbie, Sven N; Böttger, Erik C; Sander, Peter (2022). Apramycin overcomes the inherent lack of antimicrobial bactericidal activity in Mycobacterium abscessus. Antimicrobial Agents and Chemotherapy, 66(2):e0151021.

Dieterich, Cora L; Probst, Silke I; Ueoka, Reiko; Sandu, Ioana; Schäfle, Daniel; Molin, Michael Dal; Minas, Hannah A; Costa, Rodrigo; Oxenius, Annette; Sander, Peter; Piel, Jörn (2022). Aquimarins, Peptide Antibiotics with Amino-Modified C-Termini from a Sponge-Derived Aquimarina sp. Bacterium. Angewandte Chemie Internationale Edition, 61(8):e202115802.

Babu Sait, Mohammed Rizwan; Koliwer-Brandl, Hendrik; Stewart, Jessica A; Swarts, Benjamin M; Jacobsen, Marc; Ioerger, Thomas R; Kalscheuer, Rainer (2022). PPE51 mediates uptake of trehalose across the mycomembrane of Mycobacterium tuberculosis. Scientific Reports, 12(1):2097.

Waeckerle-Men, Ying; Kotkowska, Zuzanna K; Bono, Géraldine; Duda, Agathe; Kolm, Isabel; Varypataki, Eleni Maria; Amstutz, Beat; Meuli, Michael; Høgset, Anders; Kündig, Thomas M; Halin, Cornelia; Sander, Peter; Johansen, Pål (2022). Photochemically-Mediated Inflammation and Cross-Presentation of Mycobacterium bovis BCG Proteins Stimulates Strong CD4 and CD8 T-Cell Responses in Mice. Frontiers in Immunology, 13:815609.

Herren, Sebastian C; Huemer, Markus; Acevedo, Claudio T; Gómez-Mejia, Alejandro; Andreoni, Federica; Mairpady Shambat, Srikanth; Hasse, Barbara; Zbinden, Reinhard; Brugger, Silvio D; Zinkernagel, Annelies S (2022). Assessing Antibiotic Tolerance of Staphylococcus aureus Derived Directly from Patients by the Replica Plating Tolerance Isolation System (REPTIS). Antimicrobial Agents and Chemotherapy, 66(1):e0096721.

Hafezi, Farhad; Hosny, Mohammed; Shetty, Rohit; Knyazer, Boris; Chen, Shihao; Wang, Qinmei; Hashemi, Hassan; Torres-Netto, Emilio A; PACK-CXL Working Group (2022). PACK-CXL vs. antimicrobial therapy for bacterial, fungal, and mixed infectious keratitis: a prospective randomized phase 3 trial. Eye and vision, 9(1):2.

Swart, A Leoni; Hilbi, Hubert (2022). Legionella pneumophila. In: Janes, S M. Encyclopedia of Respiratory Medicine. Amsterdam: Elsevier, 28-39.

Brilkova, Margarita. Exploring the effects of error-prone protein synthesis on neuronal homeostasis and aging. 2022, University of Zurich, Faculty of Science.

Ifrid, Estelle; Ouertatani-Sakouhi, Hajer; Jauslin, Tania; Kicka, Sebastien; Chiriano, Gianpaolo; Harrison, Christopher F; Hilbi, Hubert; Scapozza, Leonardo; Soldati, Thierry; Cosson, Pierre (2022). 5-ethyl-2'-deoxyuridine fragilizes Klebsiella pneumoniae outer wall and facilitates intracellular killing by phagocytic cells. PLoS ONE, 17(10):e0269093.

Muigg, Veronika; Cuénod, Aline; Purushothaman, Srinithi; Siegemund, Martin; Wittwer, Matthias; Pflüger, Valentin; Schmidt, Kristina M; Weisser, Maja; Ritz, Nicole; Widmer, Andreas; Goldenberger, Daniel; Hinic, Vladimira; Roloff, Tim; Søgaard, Kirstine K; Egli, Adrian; Seth-Smith, Helena M B (2022). Diagnostic challenges within the Bacillus cereus-group: finding the beast without teeth. New Microbes and New Infections, 49-50:101040.

Oborská-Oplová, Michaela; Fischer, Ute; Altvater, Martin; Panse, Vikram Govind (2022). Eukaryotic Ribosome assembly and Nucleocytoplasmic Transport. In: Walker, John M. Ribosome Biogenesis : Methods and Protocols. New York, NY: Springer, 99-126.

Diebold, Martin; Meola, Marco; Purushothaman, Srinithi; Siewert, Lena K; Pössnecker, Elisabeth; Roloff, Tim; Lindberg, Raija Lp; Kuhle, Jens; Kappos, Ludwig; Derfuss, Tobias; Egli, Adrian; Pröbstel, Anne-Katrin (2022). Gut microbiota composition as a candidate risk factor for dimethyl fumarate-induced lymphopenia in multiple sclerosis. Gut Microbes, 14(1):2147055.

2021

Cortés Sanchón, Adrián; Santhosh Kumar, Harshitha; Mantovani, Matilde; Osinnii, Ivan; Mateos, José María; Kaech, Andres; Shcherbakov, Dimitri; Akbergenov, Rashid; Böttger, Erik C (2021). ER-misfolded proteins become sequestered with mitochondria and impair mitochondrial function. Communications Biology, 4(1):1350.

Maffei, Enea; Shaidullina, Aisylu; Burkolter, Marco; Heyer, Yannik; Estermann, Fabienne; Druelle, Valentin; Sauer, Patrick; Willi, Luc; Michaelis, Sarah; Hilbi, Hubert; Thaler, David S; Harms, Alexander (2021). Systematic exploration of Escherichia coli phage-host interactions with the BASEL phage collection. PLoS Biology, 19(11):e3001424.

Becker, Katja; Cao, Sha; Nilsson, Anna; Erlandsson, Maria; Hotop, Sven-Kevin; Kuka, Janis; Hansen, Jon; Haldimann, Klara; Grinberga, Solveiga; Berruga-Fernández, Talia; Huseby, Douglas L; Shariatgorji, Reza; Lindmark, Evelina; Platzack, Björn; Böttger, Erik C; Crich, David; Friberg, Lena E; Vingsbo Lundberg, Carina; Hughes, Diarmaid; Brönstrup, Mark; Andrén, Per E; Liepinsh, Edgars; Hobbie, Sven N (2021). Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis. EBioMedicine, 73:103652.

Cortés Sanchón, Adrián. Mitochondria and ER: Partners in Crime? ERAMS, a Novel Pathway for Mitochondrial Sequestration of ER Misfolded Proteins. 2021, University of Zurich, Faculty of Science.

Greiner, Michael; Anagnostopoulos, Alexia; Pohl, Daniel; Zbinden, Reinhard; Zbinden, Andrea (2021). A rare case of severe gastroenteritis caused by Aeromonas hydrophila after colectomy in a patient with anti-Hu syndrome: a case report. BMC Infectious Diseases, 21:1097.

Moore, James; Osinnii, Ivan; Grimm, Amandine; Oettinghaus, Björn; Eckert, Anne; Frank, Stephan; Böttger, Erik C (2021). Silencing of the ER and Integrative Stress Responses in the Liver of Mice with Error-Prone Translation. Cells, 10(11):2856.

Katic, A; Hüsler, D; Letourneur, François; Hilbi, Hubert (2021). Dictyostelium Dynamin Superfamily GTPases Implicated in Vesicle Trafficking and Host-Pathogen Interactions. Frontiers in Cell and Developmental Biology, 9:731964.

Böck, Désirée; Hüsler, Dario; Steiner, Bernhard; Medeiros, João M; Welin, Amanda; Radomska, Katarzyna A; Hardt, Wolf-Dietrich; Pilhofer, Martin; Hilbi, Hubert (2021). The Polar Legionella Icm/Dot T4SS Establishes Distinct Contact Sites with the Pathogen Vacuole Membrane. mBio, 12(5):e0218021.

Pirrone, Michael G; Hobbie, Sven N; Vasella, Andrea; Böttger, Erik C; Crich, David (2021). Influence of ring size in conformationally restricted ring I analogs of paromomycin on antiribosomal and antibacterial activity. RSC Medicinal Chemistry, 12(9):1585-1591.

Adam, Kai-Manuel; Osthoff, Michael; Lamoth, Frédéric; Conen, Anna; Erard, Véronique; Boggian, Katia; Schreiber, Peter W; Zimmerli, Stefan; Bochud, Pierre-Yves; Neofytos, Dionysios; Fleury, Mapi; Fankhauser, Hans; Goldenberger, Daniel; Mühlethaler, Konrad; Riat, Arnaud; Zbinden, Reinhard; Kronenberg, Andreas; Quiblier, Chantal; Marchetti, Oscar; Khanna, Nina (2021). Trends of the Epidemiology of Candidemia in Switzerland: A 15-Year FUNGINOS Survey. Open Forum Infectious Diseases, 8(10):ofab471.

Deneka, Dawid; Rutz, Sonja; Hutter, Cedric A J; Seeger, Markus A; Sawicka, Marta; Dutzler, Raimund (2021). Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains. Nature Communications, 12:5435.

Gysin, Marina; Acevedo, Claudio Tirso; Haldimann, Klara; Bodendoerfer, Elias; Imkamp, Frank; Bulut, Karl; Buehler, Philipp Karl; Brugger, Silvio Daniel; Becker, Katja; Hobbie, Sven N (2021). Antimicrobial susceptibility patterns of respiratory Gram-negative bacterial isolates from COVID-19 patients in Switzerland. Annals of Clinical Microbiology and Antimicrobials, 20:64.

Striednig, Bianca; Lanner, Ulrike; Niggli, Selina; Katic, Ana; Vormittag, Simone; Brülisauer, Sabrina; Hochstrasser, Ramon; Kaech, Andres; Welin, Amanda; Flieger, Antje; Ziegler, Urs; Schmidt, Alexander; Hilbi, Hubert; Personnic, Nicolas (2021). Quorum sensing governs a transmissive Legionella subpopulation at the pathogen vacuole periphery. EMBO Reports, 22(9):e52972.

Kolesnik-Goldmann, Natalia; Bodendoerfer, Elias; Röthlin, Kim; Herren, Sebastian; Imkamp, Frank; Marchesi, Martina; Mancini, Stefano (2021). Rapid Detection of PBP2a in Staphylococci from Shortly Incubated Subcultures of Positive Blood Cultures by an Immunochromatographic Assay. Microbiology Spectrum, 9(1):e0046221.

Becker, Katja; Aranzana-Climent, Vincent; Cao, Sha; Nilsson, Anna; Shariatgorji, Reza; Haldimann, Klara; Platzack, Björn; Hughes, Diarmaid; Andrén, Per E; Böttger, Erik C; Friberg, Lena E; Hobbie, Sven N (2021). Efficacy of EBL-1003 (apramycin) against Acinetobacter baumannii lung infections in mice. Clinical Microbiology and Infection, 27(9):1315-1321.

Oborská-Oplová, Michaela. Evolutionary Insights into eukaryotic ribosome biogenesis. 2021, ETH Zürich.

Walter, Adrian; Bodendoerfer, Elias; Kolesnik-Goldmann, Natalia; Mancini, Stefano (2021). Rapid identification of CTX-M-type extended-spectrum β-lactamase-producing Enterobacterales from blood cultures using a multiplex lateral flow immunoassay. Journal of Global Antimicrobial Resistance, 26:130-132.

Lubriks, Dimitrijs; Zogota, Rimants; Sarpe, Vikram A; Matsushita, Takahiko; Sati, Girish C; Haldimann, Klara; Gysin, Marina; Böttger, Erik C; Vasella, Andrea; Suna, Edgars; Hobbie, Sven N; Crich, David (2021). Synthesis and Antibacterial Activity of Propylamycin Derivatives Functionalized at the 5''- and Other Positions with a View to Overcoming Resistance Due to Aminoglycoside Modifying Enzymes. ACS Infectious Diseases, 7(8):2413-2424.

Gerhardy, Stefan; Oborská-Oplová, Michaela; Gillet, Ludovic; Börner, Richard; van Nues, Rob; Leitner, Alexander; Michel, Erich; Petkowski, Janusz J; Granneman, Sander; Sigel, Roland K O; Aebersold, Ruedi; Panse, Vikram Govind (2021). Puf6 primes 60S pre-ribosome nuclear export at low temperature. Nature Communications, 12:4696.

Yoganathan, Priyatharsan; Rossel, Jean-Benoit; Jordi, Sebastian Bruno Ulrich; Franc, Yannick; Biedermann, Luc; Misselwitz, Benjamin; Hausmann, Martin; Rogler, Gerhard; Scharl, Michael; Frey-Wagner, Isabelle; Swiss IBD Cohort Study Group (2021). Genotype-phenotype associations of polymorphisms within the gene locus of NOD-like receptor pyrin domain containing 3 in Swiss inflammatory bowel disease patients. BMC Gastroenterology, 21:310.

Li, Tingting; Cai, Hongmin; Yao, Hebang; Zhou, Bingjie; Zhang, Ning; van Vlissingen, Martje Fentener; Kuiken, Thijs; Han, Wenyu; GeurtsvanKessel, Corine H; Gong, Yuhuan; Zhao, Yapei; Shen, Quan; Qin, Wenming; Tian, Xiao-Xu; Peng, Chao; Lai, Yanling; Wang, Yanxing; Hutter, Cedric A J; Kuo, Shu-Ming; Bao, Juan; Liu, Caixuan; Wang, Yifan; Richard, Audrey S; Raoul, Hervé; Lan, Jiaming; Seeger, Markus A; Cong, Yao; Rockx, Barry; Wong, Gary; Bi, Yuhai; et al (2021). A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection. Nature Communications, 12:4635.

Striednig, Bianca. Quorum sensing regulates the heterogeneity of transmissive traits in sessile and intracellular Legionella pneumophila. 2021, University of Zurich, Faculty of Science.

Zürcher, K; Reichmuth, M L; Ballif, M; Loiseau, C; Borrell, S; Reinhard, M; Skrivankova, V; Hömke, R; Sander, P; Avihingsanon, A; Abimiku, A G; Marcy, O; Collantes, J; Carter, E Jane; Wilkinson, R J; Cox, H; Yotebieng, M; Huebner, R; Fenner, L; Böttger, E C; Gagneux, S; Egger, M (2021). Mortality from drug-resistant tuberculosis in high-burden countries comparing routine drug susceptibility testing with whole-genome sequencing: a multicentre cohort study. The Lancet Microbe, 2(7):e320-e330.

Sengupta, Srabasti; Nayak, Barsa; Meuli, Michael; Sander, Peter; Mishra, Snehasish; Sonawane, Avinash (2021). Mycobacterium tuberculosis Phosphoribosyltransferase Promotes Bacterial Survival in Macrophages by Inducing Histone Hypermethylation in Autophagy-Related Genes. Frontiers in Cellular and Infection Microbiology, 11:676456.

Trinco, Gianluca; Arkhipova, Valentina; Garaeva, Alisa A; Hutter, Cedric A J; Seeger, Markus A; Guskov, Albert; Slotboom, Dirk J (2021). Kinetic mechanism of Na$^{+}$-coupled aspartate transport catalyzed by Glt$_{Tk}$. Communications Biology, 4:751.

Moore, James; Akbergenov, Rashid; Nigri, Martina; Isnard-Petit, Patricia; Grimm, Amandine; Seebeck, Petra; Restelli, Lisa; Frank, Stephan; Eckert, Anne; Thiam, Kader; Wolfer, David P; Shcherbakov, Dimitri; Böttger, Erik C (2021). Random errors in protein synthesis activate an age-dependent program of muscle atrophy in mice. Communications Biology, 4:703.

Dharuman, Suresh; Wilt, Laura A; Liu, Jiuyu; Reeve, Stephanie M; Thompson, Carl W; Elmore, John M; Shcherbakov, Dimitri; Lee, Robin B; Böttger, Erik C; Lee, Richard E (2021). Synthesis, antibacterial action, and ribosome inhibition of deoxyspectinomycins. Journal of Antibiotics, 74(6):381-396.

Bachofner, Jacqueline Alexandra; Ikenberg, Kristian; Schulthess, Bettina; Nemeth, Johannes (2021). Disseminated Mycobacterium simiae and Mycobacterium avium infection causing an immune reconstitution inflammatory syndrome in a female patient with HIV infection. BMJ Case Reports, 14(5):e241037.

Meier, Gianmarco. Extending the Toolset to Explore ABC Transporters in vivo. 2021, University of Zurich, Faculty of Science.

Dailler, David; Dorst, Andrea; Schäfle, Daniel; Sander, Peter; Gademann, Karl (2021). Novel fidaxomicin antibiotics through site-selective catalysis. Communications Chemistry, 4:59.

Hüsler, Dario; Steiner, Bernhard; Welin, Amanda; Striednig, Bianca; Swart, A Leoni; Molle, Virginie; Hilbi, Hubert; Letourneur, François (2021). Dictyostelium lacking the single atlastin homolog Sey1 shows aberrant ER architecture, proteolytic processes and expansion of the Legionella-containing vacuole. Cellular Microbiology, 23(5):e13318.

Glampedakis, Emmanouil; Cassaing, Sophie; Fekkar, Arnaud; Dannaoui, Eric; Bougnoux, Marie-Elisabeth; Bretagne, Stéphane; Neofytos, Dionysios; Schreiber, Peter W; Hennequin, Christophe; Morio, Florent; Shadrivova, Olga; Bongomin, Felix; Fernández-Ruiz, Mario; Bellanger, Anne Pauline; Arikan-Akdagli, Sevtap; Erard, Veronique; Aigner, Maria; Paolucci, Michela; Khanna, Nina; Charpentier, Eléna; Bonnal, Christine; Brun, Sophie; Gabriel, Frederic; Riat, Arnaud; Zbinden, Reinhard; Le Pape, Patrice; Klimko, Nikolai; Lewis, Russel E; Richardson, Malcolm; İnkaya, Ahmet Cagkan; et al (2021). Invasive aspergillosis due to Aspergillus section Usti: a multicenter retrospective study. Clinical Infectious Diseases, 72(8):1379-1385.

Schulthess, Bettina; Schäfle, Daniel; Kälin, Nicole; Widmer, Tamara; Sander, Peter (2021). Drug susceptibility distributions of Mycobacterium chimaera and other non-tuberculous mycobacteria. Antimicrobial Agents and Chemotherapy, 65(5):e02131-20.

Sou, Tomás; Hansen, Jon; Liepinsh, Edgars; Backlund, Maria; Ercan, Onur; Grinberga, Solveiga; Cao, Sha; Giachou, Paraskevi; Petersson, Anna; Tomczak, Magdalena; Urbas, Malgorzata; Zabicka, Dorota; Vingsbo Lundberg, Carina; Hughes, Diarmaid; Hobbie, Sven N; Friberg, Lena E (2021). Model-Informed Drug Development for Antimicrobials: Translational PK and PK/PD Modeling to Predict an Efficacious Human Dose for Apramycin. Clinical Pharmacology and Therapeutics, 109(4):1063-1073.

Ramette, Alban; Gasser, Michael; Nordmann, Patrice; Zbinden, Reinhard; Schrenzel, Jacques; Perisa, Damir; Kronenberg, Andreas (2021). Temporal and regional incidence of carbapenemase-producing Enterobacterales, Switzerland, 2013 to 2018. Eurosurveillance, 26(15):1900760.

Simmen, Simona; Maane, Max; Rogler, Sarah; Baebler, Katherina; Lang, Silvia; Cosin-Roger, Jesus; Atrott, Kirstin; Frey-Wagner, Isabelle; Spielmann, Partick; Wenger, Roland H; Weder, Bruce; Zeitz, Jonas; Vavricka, Stephan R; Rogler, Gerhard; de Vallière, Cheryl; Hausmann, Martin; Ruiz, Pedro A (2021). Hypoxia Reduces the Transcription of Fibrotic Markers in the Intestinal Mucosa. Inflammatory Intestinal Diseases, 6(2):87-100.

Leung, Yau Kei Stefan; Ledergerber, Bruno; Eberhard, Nadia; Mestres, Carlos A; Rancic, Zoran; Zimmermann, Alexander; Zbinden, Reinhard; Brugger, Silvio D; Zinkernagel, Annelies S; Hasse, Barbara (2021). Open wounds and rifampicin therapy are associated with rifampicin resistance among staphylococcal vascular graft/endograft infections. JAC - Antimicrobial Resistance, 3(1):dlab041.

Shcherbakov, Dimitri; Juskeviciene, Reda; Corés Sanchón, A; Brilkova, Margarita; Rehrauer, Hubert; Laczko, Endre; Böttger, E C (2021). Mitochondrial Mistranslation in Brain Provokes a Metabolic Response Which Mitigates the Age-Associated Decline in Mitochondrial Gene Expression. International Journal of Molecular Sciences, 22(5):2746.

Scherbakov, Dimitri; Duscha, Stefan; Juskeviciene, Reda; Restelli, Lisa; Frank, Stephan; Laczko, Endre; Boettger, Erik C (2021). Mitochondrial misreading in skeletal muscle accelerates metabolic aging and confers lipid accumulation and increased inflammation. RNA, 27(3):265-272.

Shahsavar, Azadeh; Stohler, Peter; Bourenkov, Gleb; Zimmermann, Iwan; Siegrist, Martin; Guba, Wolfgang; Pinard, Emmanuel; Sinning, Steffen; Seeger, Markus A; Schneider, Thomas R; Dawson, Roger J P; Nissen, Poul (2021). Structural insights into the inhibition of glycine reuptake. Nature, 591(7851):677-681.

Hanna, Nabil; Koliwer-Brandl, Hendrik; Lefrançois, Louise H; Kalinina, Vera; Cardenal-Muñoz, Elena; Appiah, Joddy; Leuba, Florence; Gueho, Aurélie; Hilbi, Hubert; Soldati, Thierry; Barisch, Caroline (2021). Zn 2+ Intoxication of Mycobacterium marinum during Dictyostelium discoideum Infection Is Counteracted by Induction of the Pathogen Zn 2+ Exporter CtpC. mBio, 12:e01313-20.

Maurer, Steven M; Kursawe, Laura; Rahm, Stefan; Prinz, Julia; Zinkernagel, Annelies S; Moter, Annette; Kuster, Stefan P; Zbinden, Reinhard; Zingg, Patrick O; Achermann, Yvonne (2021). Cutibacterium avidum resists surgical skin antisepsis in the groin-a potential risk factor for periprosthetic joint infection: a quality control study. Antimicrobial Resistance and Infection Control, 10:27.

Coscolla, Mireia; Gagneux, Sebastien; Menardo, Fabrizio; Loiseau, Chloé; Ruiz-Rodriguez, Paula; Borrell, Sonia; et al; Fenner, Lukas; Böttger, Erik C (2021). Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history. Microbial Genomics, 7(2):1-14.

Daryadel, Arezoo; Ruiz, Pedro A; Gehring, Nicole; Stojanovic, Dragana; Ugrica, Marko; Bettoni, Carla; Sabrautzki, Sibylle; Pastor-Arroyo, Eva-Maria; Frey-Wagner, Isabelle; Lorenz-Depiereux, Bettina; Strom, Tim M; de Angelis, Martin Hrabě; Rogler, Gerhard; Wagner, Carsten A; Rubio-Aliaga, Isabel (2021). Systemic Jak1 activation provokes hepatic inflammation and imbalanced FGF23 production and cleavage. FASEB Journal, 35(2):e21302.

Sonousi, Amr; Quirke, Jonathan C K; Waduge, Prabuddha; Janusic, Tanja; Gysin, Marina; Haldimann, Klara; Xu, Shan; Hobbie, Sven N; Sha, Su-Hua; Schacht, Jochen; Chow, Christine S; Vasella, Andrea; Böttger, Erik C; Crich, David (2021). An Advanced Apralog with Increased in vitro and in vivo Activity toward Gram-negative Pathogens and Reduced ex vivo Cochleotoxicity. ChemMedChem, 16(2):335-339.

Ghielmetti, Giovanni; Rosato, Giuliana; Trovato, Alberto; Friedel, Ute; Kirchgaessner, Constanze; Perroulaz, Carmen; Pendl, Wolfgang; Schulthess, Bettina; Bloemberg, Guido V; Keller, Peter M; Stephan, Roger; Tortoli, Enrico (2021). Mycobacterium helveticum sp. nov., a novel slowly growing mycobacterial species associated with granulomatous lesions in adult swine. International Journal of Systematic and Evolutionary Microbiology, 71(1):004615.

Personnic, Nicolas; Striednig, Bianca; Hilbi, Hubert (2021). Quorum sensing controls persistence, resuscitation, and virulence of Legionella subpopulations in biofilms. The ISME journal, 15(1):196-210.

Allerberger, F; Wenzel, J; Zbinden, R; Zbinden, A (2021). Hepatitis E – eine unterschätzte Zoonose. Internistische Praxis, 63(4):731-740.

Schäfle, Daniel; Selchow, Petra; Borer, Barbara; Meuli, Michael; Rominski, Anna; Schulthess, Bettina; Sander, Peter (2021). Rifabutin is inactivated by Mycobacterium abscessus Arr. Antimicrobial Agents and Chemotherapy, 65(3):e02215-20.

2020

Dorst, Andrea; Berg, Regina; Gertzen, Christoph G W; Schäfle, Daniel; Zerbe, Katja; Gwerder, Myriam; Schnell, Simon D; Sander, Peter; Gohlke, Holger; Gademann, Karl (2020). Semisynthetic Analogs of the Antibiotic Fidaxomicin-Design, Synthesis, and Biological Evaluation. ACS Medicinal Chemistry Letters, 11(12):2414-2420.

Neff, Andrina; Chok, Lionel; von Both, Ulrich; Matt, Ulrich; Tarnutzer, Andrea; Andreoni, Federica; van der Linden, Mark; Plock, Jan A; Buehler, Philipp Karl; Brugger, Silvio Daniel; Schuepbach, Reto Andreas; Zbinden, Reinhard; Zinkernagel, Annelies Sofie (2020). Characterisation of clinical manifestations of and treatment strategies for invasive beta-haemolytic streptococcal infections in a Swiss tertiary hospital. Swiss Medical Weekly, 150:w20378.

Yusibova, Melodi; Hasman, Henrik; Clausen, Philip Thomas Lanken Conradsen; Imkamp, Frank; Wagner, Karoline; Andersen, Leif Percival (2020). CRHP Finder, a webtool for the detection of clarithromycin resistance in Helicobacter pylori from whole-genome sequencing data. Helicobacter, 25(6):e12752.

Bordignon, Enrica; Seeger, Markus A; Galazzo, Laura; Meier, Gianmarco (2020). From in vitro towards in situ: structure-based investigation of ABC exporters by electron paramagnetic resonance spectroscopy. FEBS letters, 594:3839-3856.

Custódio, Tânia F; Das, Hrishikesh; Sheward, Daniel J; Hanke, Leo; Pazicky, Samuel; Pieprzyk, Joanna; Sorgenfrei, Michèle; Schroer, Martin A; Gruzinov, Andrey Yu; Jeffries, Cy M; Graewert, Melissa A; Svergun, Dmitri I; Dobrev, Nikolay; Remans, Kim; Seeger, Markus A; McInerney, Gerald M; Murrell, Ben; Hällberg, B Martin; Löw, Christian (2020). Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2. Nature Communications, 11:5588.

Mancini, Stefano; Bodendoerfer, Elias; Kolensnik-Goldmann, Natalia; Herren, Sebastian; Röthlin, Kim; Courvalin, Patrice; Böttger, Erik C (2020). Evaluation of standardized automated rapid antimicrobial susceptibility testing of Enterobacterales-containing blood cultures: a proof-of-principle study. Journal of Antimicrobial Chemotherapy, 75(11):3218-3229.

Lewinson, Oded; Orelle, Cédric; Seeger, Markus A (2020). Structures of ABC transporters: handle with care. FEBS letters, 594(23):3799-3814.

Swart, Anna Leoni; Gomez-Valero, Laura; Buchrieser, Carmen; Hilbi, Hubert (2020). Evolution and function of bacterial RCC1 repeat effectors. Cellular Microbiology, 22(10):e13246.

Loiseau, Chloé; Brites, Daniela; Reinhard, Miriam; Zürcher, Kathrin; Borrell, Sonia; Ballif, Marie; Fenner, Lukas; Cox, Helen; Rutaihwa, Liliana K; Wilkinson, Robert J; Yotebieng, Marcel; Carter, E Jane; Abimiku, Alash'le; Marcy, Olivier; Gotuzzo, Eduardo; Avihingsanon, Anchalee; Zetola, Nicola; Doulla, Basra; Böttger, Erik C; Egger, Matthias; Gagneux, Sebastien (2020). HIV Coinfection Is Associated with Low-Fitness rpoB Variants in Rifampicin-Resistant Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy, 64(10):e00782-20.

Wyler, J; Meyer Sauteur, P M; Zbinden, R; Berger, Christoph (2020). Improved diagnosis of cat-scratch disease with an IgM enzyme-linked immunosorbent assay for Bartonella henselae using N-lauroyl-sarcosine-insoluble protein antigen. Clinical Microbiology and Infection, 26(9):1271-1273.

Waldmann, Isabelle; Schmid, Tobias; Prinz, Julia; Mühleisen, Beda; Zbinden, Reinhard; Imhof, Laurence; Achermann, Yvonne (2020). Photodynamic therapy improves skin antisepsis as a prevention strategy in arthroplasty procedures: A pilot study. Photodiagnosis and Photodynamic Therapy, 31:101941.

Reichmuth, Martina L; Hömke, Rico; Zürcher, Kathrin; Sander, Peter; Avihingsanon, Anchalee; Collantes, Jimena; Loiseau, Chloé; Borrell, Sonia; Reinhard, Miriam; Wilkinson, Robert J; Yotebieng, Marcel; Fenner, Lukas; Böttger, Erik C; Gagneux, Sebastien; Egger, Matthias; Keller, Peter M (2020). Natural Polymorphisms in Mycobacterium tuberculosis Conferring Resistance to Delamanid in Drug-naïve Patients. Antimicrobial Agents and Chemotherapy, 64(11):e00513-20.

Plattner, Michel; Gysin, Marina; Haldimann, Klara; Becker, Katja; Hobbie, Sven N (2020). Epidemiologic, Phenotypic, and Structural Characterization of Aminoglycoside-Resistance Gene aac(3)-IV. International Journal of Molecular Sciences, 21(17):6133.

Daley, Charles L; Iaccarino, Jonathan M; Lange, Christoph; Cambau, Emmanuelle; Wallace Jr, Richard J; Andrejak, Claire; Böttger, Erik C; Brozek, Jan; Griffith, David E; Guglielmetti, Lorenzo; Huitt, Gwen A; Knight, Shandra L; Leitman, Philip; Marras, Theodore K; Olivier, Kenneth N; Santin, Miguel; Stout, Jason E; Tortoli, Enrico; van Ingen, Jakko; Wagner, Dirk; Winthrop, Kevin L (2020). Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline. Clinical Infectious Diseases, 71(4):905-913.

Daley, Charles L; Iaccarino, Jonathan M; Lange, Christoph; Cambau, Emmanuelle; Wallace, Richard J; Andrejak, Claire; Böttger, Erik C; Brozek, Jan; Griffith, David E; Guglielmetti, Lorenzo; Huitt, Gwen A; Knight, Shandra L; Leitman, Philip; Marras, Theodore K; Olivier, Kenneth N; Santin, Miguel; Stout, Jason E; Tortoli, Enrico; van Ingen, Jakko; Wagner, Dirk; Winthrop, Kevin L (2020). Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline: Executive Summary. Clinical Infectious Diseases, 71(4):e1-e36.

Kling, Sabine; Hufschmid, Fong Siang; Torres-Netto, Emilio A; Randleman, J Bradley; Willcox, Mark; Zbinden, Reinhard; Hafezi, Farhad (2020). High Fluence Increases the Antibacterial Efficacy of PACK Cross-Linking. Cornea, 39(8):1020-1026.

Dorst, Andrea; Shchelik, Inga S; Schäfle, Daniel; Sander, Peter; Gademann, Karl (2020). Synthesis and Biological Evaluation of Iodinated Fidaxomicin Antibiotics. Helvetica Chimica Acta, 103(9):e2000130.

Kaelin, M B; Kuster, S P; Hasse, B; Schulthess, B; Imkamp, F; Halbe, M; Sander, P; Sax, H; Schreiber, P W (2020). Diversity of nontuberculous mycobacteria in Heater-Cooler Devices - results from prospective surveillance. Journal of Hospital Infection, 105(3):480-485.

Bodendoerfer, Elias; Marchesi, Martina; Imkamp, Frank; Courvalin, Patrice; Böttger, Erik C; Mancini, Stefano (2020). Co-occurrence of aminoglycoside and β-lactam resistance mechanisms in aminoglycoside- non-susceptible Escherichia coli isolated in the Zurich area, Switzerland. International Journal of Antimicrobial Agents, 56(1):106019.

Daley, Charles L; Iaccarino, Jonathan M; Lange, Christoph; Cambau, Emmanuelle; Wallace, Richard J; Andrejak, Claire; Böttger, Erik C; Brozek, Jan; Griffith, David E; Guglielmetti, Lorenzo; Huitt, Gwen A; Knight, Shandra L; Leitman, Philip; Marras, Theodore K; Olivier, Kenneth N; Santin, Miguel; Stout, Jason E; Tortoli, Enrico; van Ingen, Jakko; Wagner, Dirk; Winthrop, Kevin L (2020). Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline. European Respiratory Journal, 56:2000535.

Olombrada, Miriam; Peña, Cohue; Rodríguez-Galán, Olga; Klingauf-Nerurkar, Purnima; Portugal-Calisto, Daniela; Oborská-Oplová, Michaela; Altvater, Martin; Gavilanes, José G; Martínez-Del-Pozo, Álvaro; de la Cruz, Jesús; García-Ortega, Lucía; Panse, Vikram Govind (2020). The ribotoxin α-sarcin can cleave the sarcin/ricin loop on late 60S pre-ribosomes. Nucleic Acids Research, 48(11):6210-6222.

Mancini, Stefano; Röthlin, Kim; Bodendoerfer, Elias; Herren, Sebastian; Kolesnik-Goldmann, Natalia; Courvalin, Patrice; Zbinden, Reinhard; Böttger, Erik C (2020). Tentative breakpoints and areas of technical uncertainty for early reading automated disc diffusion for Enterobacterales. Journal of Antimicrobial Chemotherapy, 75(6):1495-1505.

Weigelt, Lizzy; Plate, Andreas; Stadler, Laura; Sutter, Reto; Frustaci, Dario; Zbinden, Reinhard; Zingg, Patrick O; Gerber, Christian; Achermann, Yvonne (2020). Alpha-defensin lateral flow test does not appear to be useful in predicting shoulder periprosthetic joint infections. International Orthopaedics, 44(6):1023-1029.

Hochstrasser, Ramon; Hilbi, Hubert (2020). Legionella quorum sensing meets cyclic-di-GMP signaling. Current Opinion in Microbiology, 55(Juni):9-16.

Hochstrasser, Ramon; Hutter, Cedric A J; Arnold, Fabian M; Bärlocher, Kevin; Seeger, Markus A; Hilbi, Hubert (2020). The structure of the Legionella response regulator LqsR reveals amino acids critical for phosphorylation and dimerization. Molecular Microbiology, 113(6):1070-1084.

Poirel, Laurent; Vuillemin, Xavier; Juhas, Mario; Masseron, Amandine; Bechtel-Grosch, Ursina; Tiziani, Simon; Mancini, Stefano; Nordmann, Patrice (2020). KPC-50 confers resistance to ceftazidime-avibactam associated with reduced carbapenemase activity. Antimicrobial Agents and Chemotherapy, 64(8):e00321-20.

Zimmermann, Iwan; Egloff, Pascal; Hutter, Cedric A J; Kuhn, Benedikt T; Bräuer, Philipp; Newstead, Simon; Dawson, Roger J P; Geertsma, Eric R; Seeger, Markus A (2020). Generation of synthetic nanobodies against delicate proteins. Nature Protocols, 15(5):1707-1741.

Knobloch, Paulina; Koliwer-Brandl, Hendrik; Arnold, Fabian M; Hanna, Nabil; Gonda, Imre; Adenau, Sophia; Personnic, Nicolas; Barisch, Caroline; Seeger, Markus A; Soldati, Thierry; Hilbi, Hubert (2020). Mycobacterium marinum produces distinct mycobactin and carboxymycobactin siderophores to promote growth in broth and phagocytes. Cellular Microbiology, 22(5):e13163.

Vojáčková, Petra; Michalska, Lucyna; Nečas, Marek; Shcherbakov, Dimitri; Böttger, Erik C; Šponer, Jiří; Šponer, Judit E; Švenda, Jakub (2020). Stereocontrolled Synthesis of (-)-Bactobolin A. Journal of the American Chemical Society, 142(16):7306-7311.

Gagliardi, Aron; Selchow, Petra; Luthra, Sakshi; Schäfle, Daniel; Schulthess, Bettina; Sander, Peter (2020). KatG as Counterselection Marker for Nontuberculous Mycobacteria. Antimicrobial Agents and Chemotherapy, 64(5):e02508-19.

Arnold, Fabian M; Weber, Miriam S; Gonda, Imre; Gallenito, Marc J; Adenau, Sophia; Egloff, Pascal; Zimmermann, Iwan; Hutter, Cedric A J; Hürlimann, Lea M; Peters, Eike E; Piel, Jörn; Meloni, Gabriele; Medalia, Ohad; Seeger, Markus A (2020). The ABC exporter IrtAB imports and reduces mycobacterial siderophores. Nature, 580(7803):413-417.

Swart, A Leoni; Steiner, Bernhard; Gomez-Valero, Laura; Schütz, Sabina; Hannemann, Mandy; Janning, Petra; Irminger, Michael; Rothmeier, Eva; Buchrieser, Carmen; Itzen, Aymelt; Panse, Vikram Govind; Hilbi, Hubert (2020). Divergent Evolution of Legionella RCC1 Repeat Effectors Defines the Range of Ran GTPase Cycle Targets. mBio, 11(2):e00405-20.

Böttger, Erik C; Crich, David (2020). Aminoglycosides: Time for the Resurrection of a Neglected Class of Antibacterials? ACS Infectious Diseases, 6(2):168-172.

Galazzo, Laura; Meier, Gianmarco; Hadi Timachi, M; Hutter, Cedric A J; Seeger, Markus A; Bordignon, Enrica (2020). Spin-labeled nanobodies as protein conformational reporters for electron paramagnetic resonance in cellular membranes. Proceedings of the National Academy of Sciences of the United States of America, 117(5):2441-2448.

Hasse, Barbara; Hannan, Margaret M; Keller, Peter M; Maurer, Florian P; Sommerstein, Rami; Mertz, Dominik; et al; Bettex, Dominique; Schreiber, Peter W; Zweifel, Sandrine A; Sander, P; Schulthess, B (2020). International Society of Cardiovascular Infectious Diseases Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass. Journal of Hospital Infection, 104(2):214-235.

Hanna, Nabil; Kicka, Sébastien; Chiriano, Gianpaolo; Harrison, Christopher; Sakouhi, Hajer Ouertatani; Trofimov, Valentin; Kranjc, Agata; Nitschke, Jahn; Pagni, Marco; Cosson, Pierre; Hilbi, Hubert; Scapozza, Leonardo; Soldati, Thierry (2020). Identification of Anti-Mycobacterium and Anti-Legionella Compounds With Potential Distinctive Structural Scaffolds From an HD-PBL Using Phenotypic Screens in Amoebae Host Models. Frontiers in Microbiology, 11:266.

Swart, A Leoni; Hilbi, Hubert (2020). Phosphoinositides and the Fate of Legionella in Phagocytes. Frontiers in Immunology, 11:25.

Quirke, Jonathan C K; Rajasekaran, Parasuraman; Sarpe, Vikram A; Sonousi, Amr; Osinnii, Ivan; Gysin, Marina; Haldimann, Klara; Fang, Qiao-Jun; Shcherbakov, Dimitri; Hobbie, Sven N; Sha, Su-Hua; Schacht, Jochen; Vasella, Andrea; Böttger, Erik C; Crich, David (2020). Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resistance Determinant. Journal of the American Chemical Society, 142(1):530-544.

Klingauf-Nerurkar, Purnima; Gillet, Ludovic C; Portugal-Calisto, Daniela; Oborská-Oplová, Michaela; Jäger, Martin; Schubert, Olga T; Pisano, Agnese; Peña, Cohue; Rao, Sanjana; Altvater, Martin; Chang, Yiming; Aebersold, Ruedi; Panse, Vikram G (2020). The GTPase Nog1 co-ordinates the assembly, maturation and quality control of distant ribosomal functional centers. eLife, 9:e52474.

Kuhn, Benedikt T; Zimmermann, Iwan; Egloff, Pascal; Hürlimann, Lea M; Hutter, Cedric A J; Miscenic, Christian; Dawson, Roger J P; Seeger, Markus A; Geertsma, Eric R (2020). Biotinylation of Membrane Proteins for Binder Selections. In: Perez, Camilo; Maier, Timm. Expression, Purification, and Structural Biology of Membrane Proteins. Switzerland: Springer, 151-165.

Bodendörfer, Elias. Co-occurrence of aminoglycoside and β-lactam resistance mechanisms in aminoglycoside- non-susceptible Escherichia coli isolated in the Zurich area, Switzerland. 2020, University of Zurich, Faculty of Medicine.

Egli, Adrian; Battegay, Manuel; Büchler, Andrea C; Bühlmann, Peter; Calandra, Thierry; Eckert, Philippe; Furrer, Hansjakob; Greub, Gilbert; Jakob, Stephan M; Kaiser, Laurent; Leib, Stephen L; Marsch, Stephan; Meinshausen, Nicolai; Pagani, Jean-Luc; Pugin, Jerome; Rätsch, Gunnar; Schrenzel, Jacques; Schüpbach, Reto; Siegemund, Martin; Zamboni, Nicola; Zbinden, Reinhard; Zinkernagel, Annelies; Borgwardt, Karsten (2020). SPHN/PHRT: forming a Swiss-wide infrastructure for data-driven sepsis research. In: Pape-Haugaard, Louise B; Lovis, Christian; Cort Madsen, Inge; Weber, Patrick; Hostrup Nielsen, Per; Scott, Philip. Digital Personalized Health and Medicine. Amsterdam: I O S Press, 1163-1167.

Lamrabet, Otmane; Melotti, Astrid; Burdet, Frédéric; Hanna, Nabil; Perrin, Jackie; Nitschke, Jahn; Pagni, Marco; Hilbi, Hubert; Soldati, Thierry; Cosson, Pierre (2020). Transcriptional Responses of Dictyostelium discoideum Exposed to Different Classes of Bacteria. Frontiers in Microbiology, 11:410.

2019

Wolfensberger, Aline; Kuster, Stefan P; Marchesi, Martina; Zbinden, Reinhard; Hombach, Michael (2019). The effect of varying multidrug-resistence (MDR) definitions on rates of MDR gram-negative rods. Antimicrobial Resistance and Infection Control, 8:193.

Personnic, Nicolas; Striednig, Bianca; Lezan, Emmanuelle; Manske, Christian; Welin, Amanda; Schmidt, Alexander; Hilbi, Hubert (2019). Quorum sensing modulates the formation of virulent Legionella persisters within infected cells. Nature Communications, 10(1):5216.

Knobloch, Paulina. The role of Mycobacterium marinum mycobactin siderophores and secreted phosphatases for pathogen vacuole formation and intracellular replication. 2019, University of Zurich, Faculty of Science.

Salcher, Michaela M; Schaefle, Daniel; Kaspar, Melissa; Neuenschwander, Stefan M; Ghai, Rohit (2019). Evolution in action: habitat transition from sediment to the pelagial leads to genome streamlining in Methylophilaceae. The ISME journal, 13(11):2764-2777.

Hochstrasser, Ramon. Functional and structural analysis of the Legionella Lqs-LvbR-cyclic di-GMP regulatory network. 2019, University of Zurich, Faculty of Science.

Mancini, Stefano; Keller, Peter M; Greiner, Michael; Bruderer, Vera; Imkamp, Frank (2019). Detection of NDM-19, a novel variant of the New Delhi metallo-β-lactamase with increased carbapenemase activity under zinc-limited conditions, in Switzerland. Diagnostic Microbiology and Infectious Disease, 95(3):114851.

Dal Molin, Michael; Selchow, Petra; Schäfle, Daniel; Tschumi, Andreas; Ryckmans, Thomas; Laage-Witt, Stephan; Sander, Peter (2019). Identification of novel scaffolds targeting Mycobacterium tuberculosis. Journal of Molecular Medicine, 97(11):1601-1613.

Shcherbakov, Dmitri; Teo, Youjin; Boukari, Heithem; Cortes-Sanchon, Adrian; Mantovani, Matilde; Osinnii, Ivan; Moore, James; Juskeviciene, Reda; Brilkova, Margarita; Duscha, Stefan; Kumar, Harshitha Santhosh; Laczko, Endre; Rehrauer, Hubert; Westhof, Eric; Akbergenov, Rashid; Böttger, Erik C (2019). Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis. Communications Biology, 2:381.

Sati, Girish C; Sarpe, Vikram A; Furukawa, Takayuki; Mondal, Sujit; Mantovani, Matilde; Hobbie, Sven N; Vasella, Andrea; Böttger, Erik C; Crich, David (2019). Modification at the 2'-Position of the 4,5-Series of 2-Deoxystreptamine Aminoglycoside Antibiotics To Resist Aminoglycoside Modifying Enzymes and Increase Ribosomal Target Selectivity. ACS Infectious Diseases, 5(10):1718-1730.

Wagner, Karoline; Preiswerk, Benjamin; Keller, Peter M; Schulthess, Bettina (2019). Defining threshold values in microscopic examination and qPCR for optimal performance of line probe assays for resistance detection in Mycobacterium tuberculosis complex. Diagnostic Microbiology and Infectious Disease, 95(2):159-161.

Hilbi, Hubert; Kortholt, Arjan (2019). Role of the small GTPase Rap1 in signal transduction, cell dynamics and bacterial infection. Small GTPases, 10(5):336-342.

Pop, Roxana; Estermann, Lea; Schulthess, Bettina; Eberhard, Nadia (2019). Deep infection with Mycobacterium marinum : successful treatment of a frequently misdiagnosed disease. BMJ Case Reports, 12(8):e229663.

Mancini, Stefano; Marchesi, Martina; Imkamp, Frank; Wagner, Karoline; Keller, Peter M; Quiblier, Chantal; Bodendoerfer, Elias; Courvalin, Patrice; Böttger, Erik C (2019). Population-based inference of aminoglycoside resistance mechanisms in Escherichia coli. EBioMedicine, 46:184-192.

Imkamp, Frank; Lauener, Francis N; Pohl, Daniel; Lehours, Philippe; Vale, Filipa F; Jehanne, Quentin; Zbinden, Reinhard; Keller, Peter M; Wagner, Karoline (2019). Rapid Characterization of Virulence Determinants in Helicobacter pylori Isolated from Non-Atrophic Gastritis Patients by Next-Generation Sequencing. Journal of Clinical Medicine, 8(7):1030.

Juskeviciene, Reda. Exploring the Phenotype of Mrps5-Associated Mitochondrial Mistranslation. 2019, University of Zurich, Faculty of Science.

Kaur, Hundeep; Hartmann, Jean-Baptiste; Jakob, Roman P; Zahn, Michael; Zimmermann, Iwan; Maier, Timm; Seeger, Markus A; Hiller, Sebastian (2019). Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach. Journal of Biomolecular NMR, 73(6-7):375-384.

Koliwer-Brandl, Hendrik; Knobloch, Paulina; Barisch, Caroline; Welin, Amanda; Hanna, Nabil; Soldati, Thierry; Hilbi, Hubert (2019). Distinct Mycobacterium marinum phosphatases determine pathogen vacuole phosphoinositide pattern, phagosome maturation, and escape to the cytosol. Cellular Microbiology, 21(6):e13008.

Drennan, Amanda C; Krishna, Shivaani; Seeger, Mark A; Andreas, Michael P; Gardner, Jennifer M; Sether, Emily K R; Jaspersen, Sue L; Rayment, Ivan (2019). Structure and function of Spc42 coiled-coils in yeast centrosome assembly and duplication. Molecular Biology of the Cell, 30(12):1505-1522.

Sonousi, Amr; Shcherbakov, Dimitri; Vasella, Andrea; Böttger, Erik C; Crich, David (2019). Synthesis, ribosomal selectivity, and antibacterial activity of netilmicin 4'-derivatives. MedChemComm, 10(6):946-950.

Arnold, Isabelle C; Zhang, Xiaozhou; Artola-Boran, Mariela; Fallegger, Angela; Sander, Peter; Johansen, Pål; Müller, Anne (2019). BATF3-dependent dendritic cells drive both effector and regulatory T-cell responses in bacterially infected tissues. PLoS Pathogens, 15(6):e1007866.

Egloff, Pascal; Zimmermann, Iwan; Arnold, Fabian M; Hutter, Cedric A J; Morger, Damien; Opitz, Lennart; Poveda, Lucy; Keserue, Hans-Anton; Panse, Christian; Roschitzki, Bernd; Seeger, Markus A (2019). Engineered peptide barcodes for in-depth analyses of binding protein libraries. Nature Methods, 16(5):421-428.

Hohl, Michael; Remm, Sille; Eskandarian, Haig A; Dal Molin, Michael; Arnold, Fabian M; Hürlimann, Lea M; Krügel, Andri; Fantner, Georg E; Sander, Peter; Seeger, Markus A (2019). Increased drug permeability of a stiffened mycobacterial outer membrane in cells lacking MFS transporter Rv1410 and lipoprotein LprG. Molecular Microbiology, 111(5):1263-1282.

Hutter, Cedric A J; Timachi, M Hadi; Hürlimann, Lea M; Zimmermann, Iwan; Egloff, Pascal; Göddeke, Hendrik; Kucher, Svetlana; Štefanić, Saša; Karttunen, Mikko; Schäfer, Lars V; Bordignon, Enrica; Seeger, Markus A (2019). The extracellular gate shapes the energy profile of an ABC exporter. Nature Communications, 10(1):2260.

Wagner, Karoline; Mancini, Stefano; Ritter, Claudia; Böttger, Erik C; Keller, Peter M (2019). Evaluation of the AID AmpC line probe assay for molecular detection of AmpC-producing Enterobacterales. Journal of Global Antimicrobial Resistance, 19:8-13.

Strumillo, Marta J; Oplová, Michaela; Viéitez, Cristina; Ochoa, David; Shahraz, Mohammed; Busby, Bede P; Sopko, Richelle; Studer, Romain A; Perrimon, Norbert; Panse, Vikram G; Beltrao, Pedro (2019). Conserved phosphorylation hotspots in eukaryotic protein domain families. Nature Communications, 10(1):1977.

Wagner, K; Springer, B; Pires, V P; Keller, P M (2019). High-throughput screening of bacterial pathogens in clinical specimens using 16S rDNA qPCR and fragment analysis. Diagnostic Microbiology and Infectious Disease, 93(4):287-292.

Juhas, Mario; Widlake, Emma; Teo, Jeanette; Huseby, Douglas L; Tyrrell, Jonathan M; Polikanov, Yury S; Ercan, Onur; Petersson, Anna; Cao, Sha; Aboklaish, Ali F; Rominski, Anna; Crich, David; Böttger, Erik C; Walsh, Timothy R; Hughes, Diarmaid; Hobbie, Sven N (2019). In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii. Journal of Antimicrobial Chemotherapy, 74(4):944-952.

Sarpe, Vikram A; Pirrone, Michael G; Haldimann, Klara; Hobbie, Sven N; Vasella, Andrea; Crich, David (2019). Synthesis of saccharocin from apramycin and evaluation of its ribosomal selectivity. MedChemComm, 10(4):554-558.

Matsushita, Takahiko; Sati, Girish C; Kondasinghe, Nuwan; Pirrone, Michael G; Kato, Takayuki; Waduge, Prabuddha; Kumar, Harshitha Santhosh; Sanchon, Adrian Cortes; Dobosz-Bartoszek, Malgorzata; Shcherbakov, Dimitri; Juhas, Mario; Hobbie, Sven N; Schrepfer, Thomas; Chow, Christine S; Polikanov, Yury S; Schacht, Jochen; Vasella, Andrea; Böttger, Erik C; Crich, David (2019). Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens. Journal of the American Chemical Society, 141(12):5051-5061.

Dengler Haunreiter, Vanina; Boumasmoud, Mathilde; Häffner, Nicola; Wipfli, Dennis; Leimer, Nadja; Rachmühl, Carole; Kühnert, Denise; Achermann, Yvonne; Zbinden, Reinhard; Benussi, Stefano; Vulin, Clement; Zinkernagel, Annelies S (2019). In-host evolution of Staphylococcus epidermidis in a pacemaker-associated endocarditis resulting in increased antibiotic tolerance. Nature Communications, 10(1):1149.

Bräuer, Philipp; Parker, Joanne L; Gerondopoulos, Andreas; Zimmermann, Iwan; Seeger, Markus A; Barr, Francis A; Newstead, Simon (2019). Structural basis for pH-dependent retrieval of ER proteins from the Golgi by the KDEL receptor. Science, 363(6431):1103-1107.

Zürcher, Kathrin; Ballif, Marie; Fenner, Lukas; Borrell, Sonia; Keller, Peter M; Gnokoro, Joachim; Marcy, Olivier; Yotebieng, Marcel; Diero, Lameck; Carter, E Jane; Rockwood, Neesha; Wilkinson, Robert J; Cox, Helen; Ezati, Nicholas; Abimiku, Alash'le G; Collantes, Jimena; Avihingsanon, Anchalee; Kawkitinarong, Kamon; Reinhard, Miriam; Hömke, Rico; Huebner, Robin; Gagneux, Sebastien; Böttger, Erik C; et al (2019). Drug susceptibility testing and mortality in patients treated for tuberculosis in high-burden countries: a multicentre cohort study. Lancet Infectious Diseases, 19(3):298-307.

Hochstrasser, Ramon; Kessler, Aline; Sahr, Tobias; Simon, Sylvia; Schell, Ursula; Gomez-Valero, Laura; Buchrieser, Carmen; Hilbi, Hubert (2019). The pleotropic Legionella transcription factor LvbR links the Lqs and c-di-GMP regulatory networks to control biofilm architecture and virulence. Environmental Microbiology, 21(3):1035-1053.

Wagner, K; Imkamp, F; Pires, V P; Keller, P M (2019). Evaluation of Lightmix Mycoplasma macrolide assay for detection of macrolide-resistant Mycoplasma pneumoniae in pneumonia patients. Clinical Microbiology and Infection, 25(3):383.e5-383.e7.

Buckley, Catherine M; Heath, Victoria L; Guého, Aurélie; Bosmani, Cristina; Knobloch, Paulina; Sikakana, Phumzile; Personnic, Nicolas; Dove, Stephen K; Michell, Robert H; Meier, Roger; Hilbi, Hubert; Soldati, Thierry; Insall, Robert H; King, Jason S (2019). PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection. PLoS Pathogens, 15(2):e1007551.

Gygli, Sebastian M; Keller, Peter M; Ballif, Marie; Blöchliger, Nicolas; Hömke, Rico; Reinhard, Miriam; Loiseau, Chloé; Ritter, Claudia; Sander, Peter; Borrell, Sonia; Loo, Jimena Collantes; Avihingsanon, Anchalee; Gnokoro, Joachim; Yotebieng, Marcel; Egger, Matthias; Gagneux, Sebastien; Böttger, Erik C (2019). Whole genome sequencing for drug resistance profile prediction in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy, 63(4):e02175-18.

Panasenko, Olesya O; Somasekharan, Syam Prakash; Villanyi, Zoltan; Zagatti, Marina; Bezrukov, Fedor; Rashpa, Ravish; Cornut, Julien; Iqbal, Jawad; Longis, Marion; Carl, Sarah H; Peña, Cohue; Panse, Vikram G; Collart, Martine A (2019). Co-translational assembly of proteasome subunits in NOT1-containing assemblysomes. Nature Structural & Molecular Biology, 26(2):110-120.

Lauener, Francis N; Imkamp, Frank; Lehours, Philippe; Buissonnière, Alice; Benejat, Lucie; Zbinden, Reinhard; Keller, Peter M; Wagner, Karoline (2019). Genetic Determinants and Prediction of Antibiotic Resistance Phenotypes in Helicobacter pylori. Journal of Clinical Medicine, 8:53.

Vukovic, S; Anagnostopoulos, A; Zbinden, R; Schönenberger, L; Guillod, C; French, L E; Navarini, A; Roider, E (2019). Schmerzhafte Lymphadenopathie nach Insektenstich – ein Fallbericht. Der Hautarzt, 70(1):47-50.

Zbinden, Reinhard (2019). Aggregatibacter Capnocytophaga, Eikenella, Kingella Pasteurella, and other fastidious or rarely encountered Gram-negative rods. In: Carroll, K C; et al. Manual of Clinical Microbiology, Twelfth Edition. Washington DC: ASM Press, 656-669.

Hochstrasser, R; Hilbi, H (2019). Migration of Acanthamoeba castellanii through Legionella Biofilms. In: Buchrieser, C; Hilbi, H. Legionella : Methods and Protocols (Second Edition). New York: Springer, 79-89.

Swart, Anna Leoni. Modulation of the small GTPase Ran by Legionella RCC1 repeat proteins. 2019, University of Zurich, Faculty of Science.

Steiner, B; Swart, L; Hilbi, H (2019). Perturbation of Legionella infection by RNA interference. In: Buchrieser, C; Hilbi, H. Legionella : Methods and Protocols (Second Edition). New York: Springer, 221-238.

Buchrieser, C; Hilbi, H (2019). Preface. In: Buchrieser, C; Hilbi, H. Legionella : Methods and Protocols (Second Edition). New York: Springer, v-xviii.

Welin, A; Weber, S; Hilbi, H (2019). Quantitative imaging flow cytometry of Legionella-containing vacuoles in dually fluorescence-labelled Dictyostelium. In: Buchrieser, C; Hilbi, H. Legionella : Methods and Protocols (Second Edition). New York: Springer, 161-177.

Personnic, Nicolas; Striednig, Bianca; Hilbi, Hubert (2019). Single cell analysis of Legionella and Legionella-infected Acanthamoeba by agarose embedment. In: Buchrieser, C; Hilbi, H. Legionella : Methods and Protocols (Second Edition). New York: Springer, 191-204.

2018

Patcas, R; Zbinden, R; Schätzle, M; Schmidlin, P R; Zehnder, M (2018). Whisky, microwave or hairdryer? Exploring the most efficient way to reduce bacterial colonisation on contaminated toothbrushes. British Dental Journal, 225(11):1007-1010.

Weber, Stephen; Steiner, Bernhard; Welin, Amanda; Hilbi, Hubert (2018). Legionella-Containing Vacuoles Capture PtdIns(4)-Rich Vesicles Derived from the Golgi Apparatus. mBio, 9(6):pii: e02420-18.

Egli, Adrian; Blanc, Dominique S; Greub, Gilbert; Keller, Peter M; Lazarevic, Vladimir; Lebrand, Aitana; Leib, Stephen; Neher, Richard A; Perreten, Vincent; Ramette, Alban; Schrenzel, Jacques; Stephan, Roger; Wagner, Karolin; Wuethrich, Daniel; Xenarios, Ioannis (2018). Improving the quality and workflow of bacterial genome sequencing and analysis: paving the way for a Switzerland-wide molecular epidemiological surveillance platform. Swiss Medical Weekly, 148:w14693.

Böni, Laura; Kuster, Stefan P; Bartik, Bianka; Zbinden, Reinhard; Zingg, Patrick O; Achermann, Yvonne (2018). Association of Cutibacterium avidum Colonization in the Groin With Obesity: A Potential Risk Factor for Hip Periprosthetic Joint Infection. Clinical Infectious Diseases, 67(12):1878-1882.

Personnic, Nicolas; Striednig, Bianca; Hilbi, Hubert (2018). Legionella quorum sensing and its role in pathogen-host interactions. Current Opinion in Microbiology, 41:29-35.

Plate, Andreas; Stadler, Laura; Sutter, Reto; Anagnostopoulos, Alexia; Frustaci, Dario; Zbinden, Reinhard; Fucentese, Sandro F; Zinkernagel, Annelies S; Zingg, Patrick O; Achermann, Yvonne (2018). Inflammatory disorders mimicking periprosthetic joint infections may result in false positive α-defensin. Clinical Microbiology and Infection, 24(11):1212.e1-1212.e6.

Akbergenov, Rashid; Duscha, Stefan; Fritz, Ann-Kristina; Juskeviciene, Reda; Oishi, Naoki; Schmitt, Karen; Shcherbakov, Dimitri; Teo, Youjin; Boukari, Heithem; Freihofer, Pietro; Isnard-Petit, Patricia; Oettinghaus, Björn; Frank, Stephan; Thiam, Kader; Rehrauer, Hubert; Westhof, Eric; Schacht, Jochen; Eckert, Anne; Wolfer, David; Böttger, Erik C (2018). Mutant MRPS5 affects mitoribosomal accuracy and confers stress-related behavioral alterations. EMBO Reports, 19(11):e46193.

Kalt, Fabian; Schulthess, Bettina; Sidler, Fabian; Herren, Sebastian; Fucentese, Sandro F; Zingg, Patrick O; Berli, Martin; Zinkernagel, Annelies S; Zbinden, Reinhard; Achermann, Yvonne (2018). Corynebacterium species rarely cause orthopedic infections. Journal of Clinical Microbiology, 56(12):e01200-18.

Hartmann, Jessica; Münch, Robert C; Freiling, Ruth-Therese; Schneider, Irene C; Dreier, Birgit; Samukange, Washington; Koch, Joachim; Seeger, Markus A; Plückthun, Andreas; Buchholz, Christian J (2018). A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors. Molecular Therapy - Methods & Clinical Development, 10:128-143.

Plate, Andreas; Kohl, Thomas A; Keller, Peter M; Majer, Sabine; Fulchini, Rosamaria; Strahm, Carol; Medugno, Cristoforo; Rancic, Zoran; Husmann, Lars; Sax, Hugo; Niemann, Stefan; Hasse, Barbara (2018). Aortic endograft infection with Mycobacterium chimaera and Granulicatella adiacens, Switzerland, 2014. Emerging Infectious Diseases, 24(9):1700-1704.

Schütz, Sabina; Michel, Erich; Damberger, Fred F; Oplová, Michaela; Peña, Cohue; Leitner, Alexander; Aebersold, Ruedi; Allain, Frederic H-T; Panse, Vikram Govind (2018). Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2. Nature Communications, 9(1):3669.

Arnold, Fabian. Structural and functional characterization of the mycobacterial siderophore transporter IrtAB. 2018, University of Zurich, Faculty of Science.

Affolter, Kristina; Schumann, Desiree M; Tamm, Michael; Jahn, Kathleen; Siebeneichler, Aline; Junker, Lilian; Wagner, Karoline; Keller, Peter M; Frei, Reno; Stolz, Daiana (2018). Multiplex PCR on the Bronchoalveolar Lavage Fluid of Immunocompromised Patients. Chest, 154(3):722-725.

Mancini, Stefano; Marchesi, Martina; Blöchliger, Nicolas; Schmid, Marc; Courvalin, Patrice; Keller, Peter M; Böttger, Erik C (2018). Combining forecast probabilities with graphical visualization for improved reporting of antimicrobial susceptibility testing. Journal of Antimicrobial Chemotherapy, 73(8):2266-2268.

Blumenthal, Stephan; Zbinden, Reinhard; Mandic, Sascha; Rüst, Christoph A; Aguirre, José; Borgeat, Alain (2018). Influence of skin disinfection prior removal of perineural catheter on bacterial colonization, contamination and local inflammation: a prospective randomized study. Minerva Anestesiologica, 84(3):319-327.

Sonousi, Amr; Sarpe, Vikram A; Brilkova, Margarita; Schacht, Jochen; Vasella, Andrea; Böttger, Erik C; Crich, David (2018). Effects of the 1- N-(4-Amino-2 S-hydroxybutyryl) and 6'- N-(2-Hydroxyethyl) Substituents on Ribosomal Selectivity, Cochleotoxicity, and Antibacterial Activity in the Sisomicin Class of Aminoglycoside Antibiotics. ACS Infectious Diseases, 4(7):1114-1120.

Hongler, J; Musaazi, J; Ledergerber, B; Eberhard, N; Sekaggya-Wiltshire, C; Keller, P M; Fehr, J; Castelnuovo, B (2018). Comparison of Löwenstein-Jensen and BACTEC MGIT 960 culture for Mycobacterium tuberculosis in people living with HIV. HIV Medicine, 19(9):654-661.

Schreiber, Peter W; Köhler, Nora; Cervera, Rosita; Hasse, Barbara; Sax, Hugo; Keller, Peter M (2018). Detection limit of Mycobacterium chimaera in water samples for monitoring medical device safety: insights from a pilot experimental series. Journal of Hospital Infection, 99(3):284-289.

Kuehl, Richard; Banderet, Florian; Egli, Adrian; Keller, Peter M; Frei, Reno; Döbele, Thomas; Eckstein, Friedrich; Widmer, Andreas F (2018). Different Types of Heater-Cooler Units and Their Risk of Transmission of Mycobacterium chimaera During Open-Heart Surgery: Clues From Device Design. Infection Control and Hospital Epidemiology, 39(7):834-840.

Keller, Peter M (2018). Urban transmission of tuberculosis in China. Lancet Infectious Diseases, 18(7):706-707.

Murra, May; Lützen, Lisbeth; Barut, Aynur; Zbinden, Reinhard; Lund, Marianne; Villesen, Palle; Nørskov-Lauritsen, Niels (2018). Whole-Genome Sequencing of Aggregatibacter Species Isolated from Human Clinical Specimens and Description of Aggregatibacter kilianii sp. nov. Journal of Clinical Microbiology, 56(7):pii: e00053.

Arnold, Fabian M; Hohl, Michael; Remm, Sille; Koliwer-Brandl, Hendrik; Adenau, Sophia; Chusri, Sasitorn; Sander, Peter; Hilbi, Hubert; Seeger, Markus A (2018). A uniform cloning platform for mycobacterial genetics and protein production. Scientific Reports, 8:9539.

Müller, Andreas U; Imkamp, Frank; Weber-Ban, Eilika (2018). The Mycobacterial LexA/RecA-Independent DNA Damage Response Is Controlled by PafBC and the Pup-Proteasome System. Cell Reports, 23(12):3551-3564.

Welin, Amanda; Weber, Stephen; Hilbi, Hubert (2018). Quantitative Imaging Flow Cytometry of Legionella-Infected Dictyostelium Amoebae Reveals the Impact of Retrograde Trafficking on Pathogen Vacuole Composition. Applied and Environmental Microbiology, 84(11):e00158.

Gerber, Lukas; Gaspert, Ariana; Braghetti, Antonio; Zwahlen, Hugo; Wüthrich, Rudolf; Zbinden, Reinhard; Mueller, Nicolas; Fehr, Thomas (2018). Ureaplasma and Mycoplasma in kidney allograft recipients-A case series and review of the literature. Transplant Infectious Disease:e12937.

Zimmermann, Iwan; Egloff, Pascal; Hutter, Cedric A J; Arnold, Fabian M; Stohler, Peter; Bocquet, Nicolas; Hug, Melanie N; Huber, Sylwia; Siegrist, Martin; Hetemann, Lisa; Gera, Jennifer; Gmür, Samira; Spies, Peter; Gygax, Daniel; Geertsma, Eric R; Dawson, Roger J P; Seeger, Markus A (2018). Synthetic single domain antibodies for the conformational trapping of membrane proteins. eLife, 7:e34317.

Wagner, K; Springer, B; Pires, V P; Keller, P M (2018). Molecular detection of fungal pathogens in clinical specimens by 18S rDNA high-throughput screening in comparison to ITS PCR and culture. Scientific Reports, 8:6964.

Zweifel, Sandrine A; Keller, Peter M; Hasse, Barbara; Barthelmes, Daniel; Böni, Christian (2018). Reply. Ophthalmology, 125(5):e33-e34.

Göddeke, Hendrik; Timachi, M Hadi; Hutter, Cedric A J; Galazzo, Laura; Seeger, Markus A; Karttunen, Mikko; Bordignon, Enrica; Schäfer, Lars V (2018). Atomistic Mechanism of Large-Scale Conformational Transition in a Heterodimeric ABC Exporter. Journal of the American Chemical Society, 140(13):4543-4551.

Scaiola, Alain; Peña, Cohue; Weisser, Melanie; Böhringer, Daniel; Leibundgut, Marc; Klingauf-Nerurkar, Purnima; Gerhardy, Stefan; Panse, Vikram Govind; Ban, Nenad (2018). Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit. The EMBO Journal, 37(7):e98499.

Seeger, Markus A (2018). Membrane transporter research in times of countless structures. BBA - Biochimica et Biophysica Acta, 1860(4):804-808.

Khajuria, Rajiv K; Munschauer, Mathias; Ulirsch, Jacob C; et al; Schütz, Sabina; Panse, Vikram G (2018). Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis. Cell, 173(1):90-103.e19.

Damonti, Lauro; Erard, Véronique; Garbino, Jorge; Schrenzel, Jacques; Zimmerli, Stefan; Mühlethaler, Konrad; Imhof, Alexander; Zbinden, Reinhard; Fehr, Jan; Boggian, Katia; Bruderer, Thomas; Flückiger, Ursula; Frei, Reno; Orasch, Christina; Conen, Anna; Khanna, Nina; Bregenzer, Thomas; Bille, Jacques; Lamoth, Frédéric; Marchetti, Oscar; Bochud, Pierre-Yves; Fungal Infection Network of Switzerland (FUNGINOS) (2018). Correction to: Catheter retention as a consequence rather than a cause of unfavorable outcome in candidemia. Intensive Care Medicine, 44(3):405-407.

Sommerstein, Rami; Hasse, Barbara; Marschall, Jonas; Sax, Hugo; Genoni, Michele; Schlegel, Matthias; Widmer, Andreas F; Swiss Chimaera Taskforce (2018). Global Health Estimate of Invasive Mycobacterium chimaera Infections Associated with Heater-Cooler Devices in Cardiac Surgery. Emerging Infectious Diseases, 24(3):576-578.

van Ingen, Jakko; Aksamit, Timothy; Andrejak, Claire; Böttger, Erik C; et al (2018). Treatment outcome definitions in nontuberculous mycobacterial pulmonary disease: an NTM-NET consensus statement. European Respiratory Journal, 51(3):1800170.

Becker, Katja. Structural and functional analysis of lipoprotein glycosylation in fast- and slow-growing mycobacteria. 2018, University of Zurich, Faculty of Science.

Hombach, Michael; Jetter, Marion; Blöchliger, Nicolas; Kolesnik-Goldmann, Natalia; Keller, Peter M; Böttger, Erik C (2018). Rapid disc diffusion antibiotic susceptibility testing for Pseudomonas aeruginosa, Acinetobacter baumannii and Enterococcus spp. Journal of Antimicrobial Chemotherapy, 73(2):385-391.

Wagner, Karoline; Springer, Burkard; Pires, Valeria P; Keller, Peter M (2018). Pathogen Identification by Multiplex LightMix Real-Time PCR Assay in Patients with Meningitis and Culture-Negative Cerebrospinal Fluid Specimens. Journal of Clinical Microbiology, 56(2):e01492.

Wagner, Karoline; Springer, Burkard; Imkamp, Frank; Opota, Onya; Greub, Gilbert; Keller, Peter M (2018). Detection of respiratory bacterial pathogens causing atypical pneumonia by multiplex Lightmix® RT-PCR. International Journal of Medical Microbiology : IJMM, 308(3):317-323.

Orasch, Christina; Mertz, Dominik; Garbino, Jorge; van Delden, Christian; Emonet, Stephane; Schrenzel, Jacques; Zimmerli, Stefan; Damonti, Lauro; Mühlethaler, Konrad; Imhof, Alexander; Ruef, Christian; Fehr, Jan; Zbinden, Reinhard; Boggian, Katia; Bruderer, Thomas; Flückiger, Ursula; Conen, Anna; Khanna, Nina; Frei, Reno; Bregenzer, Thomas; Lamoth, Frédéric; Erard, Véronique; Bochud, Pierre-Yves; Calandra, Thierry; Bille, Jacques; Marchetti, Oscar (2018). Fluconazole non-susceptible breakthrough candidemia after prolonged low-dose prophylaxis: a prospective FUNGINOS study. Journal of Infection, 76(5):489-495.

Walker, Timothy M; Merker, Matthias; Knoblauch, Astrid M; Helbling, Peter; Schoch, Otto D; van der Werf, Marieke J; Kranzer, Katharina; Fiebig, Lena; Kröger, Stefan; Haas, Walter; Hoffmann, Harald; Indra, Alexander; Egli, Adrian; Cirillo, Daniela M; Robert, Jérôme; Rogers, Thomas R; Groenheit, Ramona; Mengshoel, Anne T; Mathys, Vanessa; Haanperä, Marjo; van Soolingen, Dick; Niemann, Stefan; Böttger, Erik C; Keller, Peter M; MDR-TB Cluster Consortium (2018). A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study. Lancet Infectious Diseases, 18(4):431-440.

Abela, Irene A; Murer, Christian; Schuurmans, Macé M; Schmitt, Juergen W; Muller, Frabci; Imkamp, Frank; Mueller, Nicolas J; Benden, Christian (2018). A cluster of scedosporiosis in lung transplant candidates and recipients: the Zurich experience and review of the literature. Transplant Infectious Disease, 20(1):e12792.

Redondo, Javier Jareño; Keller, Peter M; Zbinden, Reinhard; Wagner, Karoline (2018). A novel RT-PCR for the detection of Helicobacter pylori and identification of clarithromycin resistance mediated by mutations in the 23S rRNA gene. Diagnostic Microbiology and Infectious Disease, 90(1):1-6.

Swart, A Leoni; Harrison, Christopher F; Eichinger, Ludwig; Steinert, Michael; Hilbi, Hubert (2018). Acanthamoeba and Dictyostelium as Cellular Models for Legionella Infection. Frontiers in Cellular and Infection Microbiology, 8:61.

Manske, Christian; Finsel, Ivo; Hoffmann, Christine; Hilbi, Hubert (2018). Analysis of Legionella Metabolism by Pathogen Vacuole Proteomics. Methods in Molecular Biology, 1841:59-76.

Seth-Smith, Helena M B; Imkamp, Frank; Tagini, Florian; Cuénod, Aline; Hömke, Rico; Jahn, Kathleen; Tschacher, Anne; Grendelmeier, Peter; Bättig, Veronika; Erb, Stefan; Reinhard, Miriam; Rütimann, Gottfried; Borrell, Sonia; Gagneux, Sebastien; Casanova, Carlo; Droz, Sara; Osthoff, Michael; Tamm, Michael; Nübel, Ulrich; Greub, Gilbert; Keller, Peter M; Egli, Adrian (2018). Discovery and Characterization of Mycobacterium basiliense sp. nov., a Nontuberculous Mycobacterium Isolated From Human Lungs. Frontiers in Microbiology, 9:3184.

Teo, You Jin. Exploring cellular adaptations to chronic loss of translational fidelity in the eukaryotic cell. 2018, University of Zurich, Faculty of Science.

Steiner, Bernhard; Weber, Stephen; Hilbi, Hubert (2018). Formation of the Legionella-containing vacuole: phosphoinositide conversion, GTPase modulation and ER dynamics. International Journal of Medical Microbiology : IJMM, 308(1):49-57.

Ajdler-Schaeffler, Evelyne; Scherrer, Alexandra U; Keller, Peter M; Anagnostopoulos, Alexia; Hofmann, Michael; Rancic, Zoran; Zinkernagel, Annelies S; Bloemberg, Guido V; Hasse, Barbara K (2018). Increased pathogen identification in vascular graft infections by the combined use of tissue cultures and 16S rRNA gene polymerase chain reaction. Frontiers in Medicine, 5:169.

Bärlocher, Kevin. Modulation of retrograde trafficking components by the Legionella pneumophila effector RidL. 2018, University of Zurich, Faculty of Science.

Achermann, Yvonne; Liu, Jared; Zbinden, Reinhard; Zingg, Patrick O; Anagnostopoulos, Alexia; Barnard, Emma; Sutter, Reto; Li, Huiying; McDowell, Andrew; Zinkernagel, Annelies S (2018). Propionibacterium avidum - a virulent pathogen causing hip periprosthetic joint infection. Clinical Infectious Diseases, 66(1):54-63.

Hutter, Cedric. Structural and mechanistic insights into the transport cycle of the heterodimeric ABC exporter TM287/288. 2018, University of Zurich, Faculty of Science.

Luthra, Sakshi; Rominski, Anna; Sander, Peter (2018). The Role of Antibiotic-Target-Modifying and Antibiotic-Modifying Enzymes in Drug Resistance. Frontiers in Microbiology, 9:2179.

Steiner, Bernhard; Weber, Stephen; Kaech, Andres; Ziegler, Urs; Hilbi, Hubert (2018). The large GTPase atlastin controls ER remodeling around a pathogen vacuole. Communicative & Integrative Biology, 11(2):1-5.

2017

Bärlocher, Kevin; Hutter, Cedric A J; Swart, A Leoni; Steiner, Bernhard; Welin, Amanda; Hohl, Michael; Letourneur, François; Seeger, Markus A; Hilbi, Hubert (2017). Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5. Nature Communications, 8(1):1543.

Rominski, Anna; Schulthess, Bettina; Müller, Daniel M; Keller, Peter M; Sander, Peter (2017). Effect of β-lactamase production and β-lactam instability on MIC testing results for Mycobacterium abscessus. Journal of Antimicrobial Chemotherapy, 72(11):3070-3078.

Hombach, Michael; Jetter, Marion; Keller, Peter M; Blöchliger, Nicolas; Kolesnik-Goldmann, Natalia; Böttger, Erik C (2017). Rapid detection of ESBL, carbapenemases, MRSA and other important resistance phenotypes within 6-8 h by automated disc diffusion antibiotic susceptibility testing. Journal of Antimicrobial Chemotherapy, 72(11):3063-3069.

Fudrini Olivencia, Begonia; Müller, Andreas U; Roschitzki, Bernd; Burger, Sibylle; Weber-Ban, Eilika; Imkamp, Frank (2017). Mycobacterium smegmatis PafBC is involved in regulation of DNA damage response. Scientific Reports, 7(1):13987.

Dal Molin, Michael; Gut, Myriam; Rominski, Anna; Haldimann, Klara; Becker, Katja; Sander, Peter (2017). Molecular Mechanisms of Intrinsic Streptomycin Resistance in Mycobacterium abscessus. Antimicrobial Agents and Chemotherapy, 62(1):e01427-17.

Mandhapati, Appi Reddy; Yang, Guanyu; Kato, Takayuki; Shcherbakov, Dimitri; Hobbie, Sven N; Vasella, Andrea; Böttger, Erik C; Crich, David (2017). Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues: Importance of the Configuration at the 6'-Position and Differences between the 6'-Amino and Hydroxy Series. Journal of the American Chemical Society, 139(41):14611-14619.

Steiner, Bernhard; Swart, Anna Leoni; Welin, Amanda; Weber, Stephen; Personnic, Nicolas; Kaech, Andres; Freyre, Christophe; Ziegler, Urs; Klemm, Robin W; Hilbi, Hubert (2017). ER remodeling by the large GTPase atlastin promotes vacuolar growth of Legionella pneumophila. EMBO Reports, 18(10):1817-1836.

Escoll, Pedro; Song, Ok-Ryul; Viana, Flávia; Steiner, Bernhard; Lagache, Thibault; Olivo-Marin, Jean-Christophe; Impens, Francis; Brodin, Priscille; Hilbi, Hubert; Buchrieser, Carmen (2017). Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages. Cell Host & Microbe, 22(3):302-316.e7.

Peña, Cohue; Hurt, Ed; Panse, Vikram Govind (2017). Eukaryotic ribosome assembly, transport and quality control. Nature Structural & Molecular Biology, 24(9):689-699.

Blöchliger, Nicolas; Keller, Peter M; Böttger, Erik C; Hombach, Michael (2017). MASTER: a model to improve and standardize clinical breakpoints for antimicrobial susceptibility testing using forecast probabilities. Journal of Antimicrobial Chemotherapy, 72(9):2553-2561.

Aggarwal, Anup; Parai, Maloy K; Shetty, Nishant; Wallis, Deeann; Woolhiser, Lisa; Hastings, Courtney; Dutta, Noton K; Galaviz, Stacy; Dhakal, Ramesh C; Shrestha, Rupesh; Wakabayashi, Shoko; Walpole, Chris; Matthews, David; Floyd, David; Scullion, Paul; Riley, Jennifer; Epemolu, Ola; Norval, Suzanne; Snavely, Thomas; Robertson, Gregory T; Rubin, Eric J; Ioerger, Thomas R; Sirgel, Frik A; van der Merwe, Ruben; van Helden, Paul D; Keller, Peter; Böttger, Erik C; Karakousis, Petros C; Lenaerts, Anne J; Sacchettini, James C (2017). Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13. Cell, 170(2):249-259.e25.

van Ingen, Jakko; Kohl, Thomas A; Kranzer, Katharina; Hasse, Barbara; Keller, Peter M; et al (2017). Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery: a molecular epidemiological study. Lancet Infectious Diseases, 17(10):1033-1041.

Bloemberg, Guido V; Braun-Kiewnick, Andrea; Tedrup, Jan; Meijerink, Carla; Durer, Elena; Ritter, Claudia; Keller, Peter M; Hombach, Michael (2017). Evaluation of the AID carbapenemase line probe assay for rapid detection and identification of carbapenemase genes in Gram-negative bacilli. Journal of Antimicrobial Chemotherapy, 72(7):1948-1954.

Meyer Sauteur, Patrick M; Marques-Maggio, Ewerton; Relly, Christa; Keller, Peter M; Clarenbach, Christian F; Berger, Christoph (2017). Asymptomatic congenital tuberculosis: A case report. Medicine, 96(29):e7562.

Matt, U; Selchow, P; Dal Molin, M; Strommer, S; Sharif, O; Schilcher, K; Andreoni, F; Stenzinger, A; Zinkernagel, A S; Zeitlinger, M; Sander, P; Nemeth, J (2017). Chloroquine enhances the antimycobacterial activity of isoniazid and pyrazinamide by reversing inflammation-induced macrophage efflux. International Journal of Antimicrobial Agents, 50(1):55-62.

Hombach, Michael; Jetter, Marion; Blöchliger, Nicolas; Kolesnik-Goldmann, Natalia; Böttger, Erik C (2017). Fully automated disc diffusion for rapid antibiotic susceptibility test results: a proof-of-principle study. Journal of Antimicrobial Chemotherapy, 72(6):1659-1668.

Damonti, Lauro; Erard, Véronique; Garbino, Jorge; Schrenzel, Jacques; Zimmerli, Stefan; Mühlethaler, Konrad; Imhof, Alexander; Zbinden, Reinhard; Fehr, Jan; Boggian, Katia; Bruderer, Thomas; Flückiger, Ursula; Frei, Reno; Orasch, Christina; Conen, Anna; Khanna, Nina; Bregenzer, Thomas; Bille, Jacques; Lamoth, Frédéric; Marchetti, Oscar; Bochud, Pierre-Yves; Fungal Infection Network of Switzerland (FUNGINOS) (2017). Catheter retention as a consequence rather than a cause of unfavorable outcome in candidemia. Intensive Care Medicine, 43(6):935-939.

Hürlimann, Lea M; Hohl, Michael; Seeger, Markus A (2017). Split tasks of asymmetric nucleotide-binding sites in the heterodimeric ABC exporter EfrCD. FEBS Journal, 284(11):1672-1687.

Sati, Girish C; Shcherbakov, Dimitri; Hobbie, Sven N; Vasella, Andrea; Böttger, Erik C; Crich, David (2017). N6', N6''', and O4' Modifications to Neomycin Affect Ribosomal Selectivity without Compromising Antibacterial Activity. ACS Infectious Diseases, 3(5):368-377.

Rominski, Anna; Selchow, Petra; Becker, Katja; Brülle, Juliane K; Dal Molin, Michael; Sander, Peter (2017). Elucidation of Mycobacterium abscessus aminoglycoside and capreomycin resistance by targeted deletion of three putative resistance genes. Journal of Antimicrobial Chemotherapy, 72(8):2191-2200.

Hombach, Michael; Weissert, Christoph; Senn, Maria Magdalena; Zbinden, Reinhard (2017). Comparison of phenotypic methods for the detection of penicillinase in Staphylococcus aureus and proposal of a practical diagnostic approach. Journal of Antimicrobial Chemotherapy, 72(4):1089-1093.

Schmölders, Johanna; Manske, Christian; Otto, Andreas; Hoffmann, Christine; Steiner, Bernhard; Welin, Amanda; Becher, Dörte; Hilbi, Hubert (2017). Comparative Proteomics of Purified Pathogen Vacuoles Correlates Intracellular Replication of Legionella pneumophila with the Small GTPase Ras-related protein 1 (Rap1). Molecular & Cellular Proteomics, 16(4):622-641.

Rominski, Anna; Roditscheff, Anna; Selchow, Petra; Böttger, Erik C; Sander, Peter (2017). Intrinsic rifamycin resistance of Mycobacterium abscessus is mediated by ADP-ribosyltransferase MAB_0591. Journal of Antimicrobial Chemotherapy, 72(2):376-384.

Timachi, M Hadi; Hutter, Cedric A J; Hohl, Michael; Assafa, Tufa; Böhm, Simon; Mittal, Anshumali; Seeger, Markus A; Bordignon, Enrica (2017). Exploring conformational equilibria of a heterodimeric ABC transporter. eLife, 6:e20236.

Hürlimann, Lea. Biochemical and functional characterization of heterodimeric ABC exporters mediating drug efflux in Enterococcus faecalis. 2017, University of Zurich, Faculty of Science.

Rominski, Anna. Characterization of antibiotic resistance genes from Mycobacterium abscessus. 2017, University of Zurich, Faculty of Science.

Zweifel, Sandrine A; Mihic-Probst, Daniela; Curcio, Christine A; Barthelmes, Daniel; Thielken, Andrea; Keller, Peter M; Hasse, Barbara; Böni, Christian (2017). Clinical and histopathologic ocular findings in disseminated mycobacterium chimaera infection after cardiothoracic surgery. Ophthalmology, 124(2):178-188.

Steiner, Bernhard. ER remodeling by the large GTPase atlastin promotes vacuole expansion and intracellular growth of the bacterial pathogen Legionella pneumophila. 2017, University of Zurich, Faculty of Science.

Blodkamp, Stefanie; Kadlec, Kristina; Gutsmann, Thomas; Quiblier, Chantal; Naim, Hassan Y; Schwarz, Stefan; von Köckritz-Blickwede, Maren (2017). Effects of SecDF on the antimicrobial functions of cathelicidins against Staphylococcus aureus. Veterinary Microbiology, 200:52-58.

Koehler, Philipp; Hamprecht, Axel; Bader, Oliver; Bekeredjian-Ding, Isabelle; Buchheidt, Dieter; Doelken, Gottfried; Elias, Johannes; Haase, Gerhard; Hahn-Ast, Corinna; Karthaus, Meinolf; Kekulé, Alexander; Keller, Peter; Kiehl, Michael; Krause, Stefan W; Krämer, Carolin; Neumann, Silke; Rohde, Holger; La Rosée, Paul; Ruhnke, Markus; Schafhausen, Philippe; Schalk, Enrico; Schulz, Katrin; Schwartz, Stefan; Silling, Gerda; Staib, Peter; Ullmann, Andrew; Vergoulidou, Maria; Weber, Thomas; Cornely, Oliver A; Vehreschild, Maria J G T (2017). Epidemiology of invasive aspergillosis and azole resistance in patients with acute leukaemia: the SEPIA study. International Journal of Antimicrobial Agents, 49(2):218-223.

Bärlocher, Kevin; Welin, Amanda; Hilbi, Hubert (2017). Formation of the legionella replicative compartment at the crossroads of retrograde trafficking. Frontiers in Cellular and Infection Microbiology, 7:482.

Gerhardy, Stefan. Functional centres of the eukaryotic ribosome: assembly to quality control. 2017, ETH Zürich.

Dal Molin, Michael. Identification of drugs targeting Mycobacterium tuberculosis. 2017, University of Zurich, Faculty of Science.

Ouertatani-Sakouhi, Hajer; Kicka, Sébastien; Chiriano, Gianpaolo; Harrison, Christopher F; Hilbi, Hubert; Scapozza, Leonardo; Soldati, Thierry; Cosson, Pierre (2017). Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model. PLoS ONE, 12(7):e0181121.

Hochstrasser, Ramon; Hilbi, Hubert (2017). Intra-species and inter-kingdom signaling of Legionella pneumophila. Frontiers in Microbiology, 8:79.

Becker, Katja; Haldimann, Klara; Selchow, Petra; Reinau, Lukas M; Dal Molin, Michael; Sander, Peter (2017). Lipoprotein Glycosylation by Protein-O-Mannosyltransferase (MAB_1122c) Contributes to Low Cell Envelope Permeability and Antibiotic Resistance of Mycobacterium abscessus. Frontiers in Microbiology, 8:2123.

Fudrini Olivencia, Begonia. Mycobacterium smegmatis PafBC is involved in regulation of DNA damage response. 2017, University of Zurich, Faculty of Science.

Schön, T; Miotto, P; Köser, C U; Viveiros, M; Böttger, E; Cambau, E (2017). Mycobacterium tuberculosis drug-resistance testing: challenges, recent developments and perspectives. Clinical Microbiology and Infection, 23(3):154-160.

Kramer, Lovro; Renko, Miha; Završnik, Janja; Turk, Dušan; Seeger, Markus A; Vasiljeva, Olga; Grütter, Markus G; Turk, Vito; Turk, Boris (2017). Non-invasive in vivo imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin. Theranostics, 7(11):2806-2821.

Freihofer, Pietro. Ribosome-targeting antituberculosis compounds – antibacterial activity, resistance mechanisms. 2017, University of Zurich, Faculty of Science.

Kaufmann, Stefan H E; Dockrell, Hazel M; Drager, Nick; Ho, Mei Mei; McShane, Helen; Neyrolles, Olivier; Ottenhoff, Tom H M; Patel, Brij; Roordink, Danielle; Spertini, François; Stenger, Steffen; Thole, Jelle; Verreck, Frank A W; Williams, Ann; TBVAC2020 Consortium (2017). TBVAC2020: advancing tuberculosis vaccines from discovery to clinical development. Frontiers in Immunology, 8:1203.

Liu, J; Bruhn, D; Lee, R B; Zheng, Z; Janusic, T; Shcherbakov, D; Scherman, M; Boshoff, H; Das, S; Raskesh, K; Waidyarachchi, S; Brewer, T; Garcia, B; Yang, L; Bollinger, J; Robertson, G; Meibohn, B; Lenaerts, A; Ainsa, J; Böttger, E C; Lee, R E (2017). The structure-activity relationships of Spectinamide antituberculosis agents; a dissection of ribosomal inhibition and native efflux avoidance contributions. ACS Infectious Diseases, 3(1):72-88.

2016

Slepikas, Liudas; Chiriano, Gianpaolo; Perozzo, Remo; Tardy, Sébastien; Kranjc, Agata; Patthey-Vuadens, Ophélie; Ouertatani-Sakouhi, Hajer; Kicka, Sébastien; Harrison, Christopher F; Scrignari, Tiziana; Perron, Karl; Hilbi, Hubert; Soldati, Thierry; Cosson, Pierre; Tarasevicius, Eduardas; Scapozza, Leonardo (2016). In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhA. Journal of Medicinal Chemistry, 59(24):10917-10928.

Peña, Cohue; Schütz, Sabina; Fischer, Ute; Chang, Yiming; Panse, Vikram G (2016). Prefabrication of a ribosomal protein subcomplex essential for eukaryotic ribosome formation. eLife, 5:e21755.

Imkamp, Frank; Keller, Peter M; Böttger, Erik C (2016). Comment on: Delamanid susceptibility testing of Mycobacterium tuberculosis using the resazurin microtitre assay and the BACTEC™ MGIT™ 960 system. Journal of Antimicrobial Chemotherapy, 71(12):3624.

Freihofer, Pietro; Akbergenov, Rashid; Teo, Youjin; Juskeviciene, Reda; Andersson, Dan I; Böttger, Erik C (2016). Nonmutational compensation of the fitness cost of antibiotic resistance in mycobacteria by overexpression of tlyA rRNA methylase. RNA, 22(12):1836-1843.

Meinel, D M; Kuehl, R; Zbinden, R; Boskova, V; Garzoni, C; Fadini, D; Dolina, M; Blümel, B; Weibel, T; Tschudin-Sutter, S; Widmer, A F; Bielicki, J A; Dierig, A; Heininger, U; Konrad, R; Berger, A; Hinic, V; Goldenberger, D; Blaich, A; Stadler, T; Battegay, M; Sing, A; Egli, A (2016). Outbreak investigation for toxigenic Corynebacterium diphtheriae wound infections in refugees from Northeast Africa and Syria in Switzerland and Germany by whole genome sequencing. Clinical Microbiology and Infection, 22(12):1003.e1-1003.e8.

Becker, Katja; Sander, Peter (2016). Mycobacterium tuberculosis lipoproteins in virulence and immunity - fighting with a double-edged sword. FEBS letters, 590(21):3800-3819.

Bossard, Daniel Andreas; Ledergerber, Bruno; Zingg, Patrick O; Gerber, Christian; Zinkernagel, Annelies S; Zbinden, Reinhard; Achermann, Yvonne (2016). Optimal length of cultivation time for isolation of propionibacterium acnes in suspected bone and joint infections is more than 7 days. Journal of Clinical Microbiology, 54(12):3043-3049.

Sander, Peter; Becker, Katja; Molin, Michael Dal (2016). Lipase processing of complex lipid antigens. Cell Chemical Biology, 23(9):1044-1046.

Hürlimann, Lea M; Corradi, Valentina; Hohl, Michael; Bloemberg, Guido V; Tieleman, D Peter; Seeger, Markus A (2016). The heterodimeric ABC transporter EfrCD mediates multidrug efflux in enterococcus faecalis. Antimicrobial Agents and Chemotherapy, 60(9):5400-5411.

Manske, Christian; Schell, Ursula; Hilbi, Hubert (2016). Metabolism of myo-inositol by legionella pneumophila promotes infection of amoebae and macrophages. Applied and Environmental Microbiology, 82(16):5000-5014.

Fascellaro, Giuseppina; Petrera, Agnese; Lai, Zon Weng; Nanni, Paolo; Grossmann, Jonas; Burger, Sibylle; Biniossek, Martin L; Gomez-Auli, Alejandro; Schilling, Oliver; Imkamp, Frank (2016). Comprehensive proteomic analysis of nitrogen-starved mycobacterium smegmatis δpup reveals the impact of pupylation on nitrogen stress response. Journal of Proteome Research, 15(8):2812-2825.

Scherrer, Alexandra U; Bloemberg, Guido; Zbinden, Reinhard; Zinkernagel, Annelies S; Fuchs, Claudio; Frauenfelder, Sandra; Rancic, Zoran; Mayer, Dieter; Hasse, Barbara (2016). Prosthetic vascular graft infections: bacterial cultures from negative-pressure-wound-therapy foams do not improve diagnostics. Journal of Clinical Microbiology, 54(8):2190-2193.

Deggim-Messmer, Vanessa; Bloemberg, Guido V; Ritter, Claudia; Voit, Antje; Hömke, Rico; Keller, Peter M; Böttger, Erik C (2016). Diagnostic molecular mycobacteriology in regions with low tuberculosis endemicity: combining real-time PCR assays for detection of multiple mycobacterial pathogens with line probe assays for identification of resistance mutations. EBioMedicine, 9:228-237.

Stucki, David; Ballif, Marie; Egger, Matthias; Furrer, Hansjakob; Altpeter, Ekkehardt; Battegay, Manuel; Droz, Sara; Bruderer, Thomas; Coscolla, Mireia; Borrell, Sonia; Zürcher, Kathrin; Janssens, Jean-Paul; Calmy, Alexandra; Mazza Stalder, Jesica; Jaton, Katia; Rieder, Hans L; Pfyffer, Gaby E; Siegrist, Hans H; Hoffmann, Matthias; Fehr, Jan; Dolina, Marisa; Frei, Reno; Schrenzel, Jacques; Böttger, Erik C; Gagneux, Sebastien; Fenner, Lukas (2016). Standard genotyping overestimates transmission of mycobacterium tuberculosis among immigrants in a low-incidence country. Journal of Clinical Microbiology, 54(7):1862-1870.

Jost, Geraldine; Bloemberg, Guido V; Hombach, Michael (2016). Improved sensitivity for meticillin resistance detection in coagulase-negative staphylococci by moxalactam antibiotic discs or a cefoxitin investigation zone. Journal of Medical Microbiology, 65(6):566-568.

Personnic, Nicolas; Bärlocher, Kevin; Finsel, Ivo; Hilbi, Hubert (2016). Subversion of retrograde trafficking by translocated pathogen effectors. Trends in Microbiology, 24(6):450-462.

Kragelund, Birthe B; Schenstrøm, Signe M; Rebula, Caio A; Panse, Vikram Govind; Hartmann-Petersen, Rasmus (2016). DSS1/Sem1, a multifunctional and intrinsically disordered protein. Trends in Biochemical Sciences, 41(5):446-459.

Rolando, Monica; Escoll, Pedro; Nora, Tamara; Botti, Joëlle; Boitez, Valérie; Bedia, Carmen; Daniels, Craig; Abraham, Gilu; Stogios, Peter J; Skarina, Tatiana; Christophe, Charlotte; Dervins-Ravault, Delphine; Cazalet, Christel; Hilbi, Hubert; Rupasinghe, Thusitha W T; Tull, Dedreia; McConville, Malcolm J; Ong, Sze Ying; Hartland, Elizabeth L; Codogno, Patrice; Levade, Thierry; Naderer, Thomas; Savchenko, Alexei; Buchrieser, Carmen (2016). Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy. Proceedings of the National Academy of Sciences of the United States of America, 113(7):1901-1906.

Hoffmann, Harald; Kohl, Thomas A; Hofmann-Thiel, Sabine; Merker, Matthias; Beckert, Patrick; Jaton, Katia; Nedialkova, Lubov; Sahalchyk, Evgeni; Rothe, Thomas; Keller, Peter M; Niemann, Stefan (2016). Delamanid and bedaquiline resistance in mycobacterium tuberculosis ancestral beijing genotype causing extensively drug-resistant tuberculosis in a tibetan refugee. American Journal of Respiratory and Critical Care Medicine, 193(3):337-340.

Naujoks, Jan; Tabeling, Christoph; Dill, Brian D; Hoffmann, Christine; Brown, Andrew S; Kunze, Mareike; Kempa, Stefan; Peter, Andrea; Mollenkopf, Hans-Joachim; Dorhoi, Anca; Kershaw, Olivia; Gruber, Achim D; Sander, Leif E; Witzenrath, Martin; Herold, Susanne; Nerlich, Andreas; Hocke, Andreas C; van Driel, Ian; Suttorp, Norbert; Bedoui, Sammy; Hilbi, Hubert; Trost, Matthias; Opitz, Bastian (2016). IFNs modify the proteome of legionella-containing vacuoles and restrict infection via IRG1-derived itaconic acid. PLoS Pathogens, 12(2):e1005408.

Greber, Basil Johannes; Gerhardy, Stefan; Leitner, Alexander; Leibundgut, Marc; Salem, Michèle; Boehringer, Daniel; Leulliot, Nicolas; Aebersold, Ruedi; Panse, Vikram Govind; Ban, Nenad (2016). Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation. Cell, 164(1-2):91-102.

Domínguez, J; Boettger, E C; Cirillo, D; Cobelens, F; Eisenach, K D; Gagneux, S; Hillemann, D; Horsburgh, R; Molina-Moya, B; Niemann, S; Tortoli, E; Whitelaw, A; Lange, C (2016). Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a TBNET/RESIST-TB consensus statement. The International Journal of Tuberculosis and Lung Disease, 20(1):24-42.

Mohanty, Soumitra; Dal Molin, Michael; Ganguli, Geetanjali; Padhi, Avinash; Jena, Prajna; Selchow, Petra; Sengupta, Srabasti; Meuli, Michael; Sander, Peter; Sonawane, Avinash (2016). Mycobacterium tuberculosis EsxO (Rv2346c) promotes bacillary survival by inducing oxidative stress mediated genomic instability in macrophages. Tuberculosis, 96:44-57.

Hombach, Michael; Ochoa, Carlos; Maurer, Florian P; Pfiffner, Tamara; Böttger, Erik C; Furrer, Reinhard (2016). Relative contribution of biological variation and technical variables to zone diameter variations of disc diffusion susceptibility testing. Journal of Antimicrobial Chemotherapy, 71(1):141-151.

Seeger, M A; Bordignon, E; Hohl, M (2016). ABC Exporters from a structural perspective. In: George, Anthony M. ABC Transporters - 40 Years on. Syndey Australia: Springer, 65-84.

Zumbühl, Dominique. Antibiotikasynergie-Testung mittels Abtötungskinetik bei multiresistenten Pseudomonas aeruginosa bei Patienten mit Cystischer Fibrose. 2016, University of Zurich, Faculty of Medicine.

Sybesma, Wilbert; Zbinden, Reinhard; Chanishvili, Nino; Kutateladze, Mzia; Chkhotua, Archil; Ujmajuridze, Aleksandre; Mehnert, Ulrich; Kessler, Thomas M (2016). Bacteriophages as Potential Treatment for Urinary Tract Infections. Frontiers in Microbiology, 7:465.

Boukari, Heithem. Cellular adaptations to ribosomal mistranslation in eukaryotes. 2016, University of Zurich, Faculty of Science.

Morand, Grégoire B; Fellmann, Jonas; Laske, Roman D; Weisert, Jan U; Soltermann, Alex; Zbinden, Reinhard; Probst, Rudolf; Huber, Gerhard F (2016). Detection of Helicobacter pylori in head and neck cancer patients: Results from a prospective comparative study combining serology, PCR, and rapid urease test. Head and Neck, 38(5):769-774.

Herren, Sebastian. Entwicklung der minimalen Hemmkonzentrationen von Cefoxitin gegen klinische Staphylococcus aureus zwischen 2007 und 2015. 2016, University of Zurich, Faculty of Medicine.

Schulthess, Bettina; Bloemberg, Guido V; Zbinden, Andrea; Mouttet, Forouhar; Zbinden, Reinhard; Böttger, Erik C; Hombach, Michael (2016). Evaluation of the Bruker MALDI Biotyper for the identification of fastidious Gram-negative rods. Journal of Clinical Microbiology, 54(3):543-548.

Harrison, C F; Hilbi, H (2016). Identification of anti-infective compounds using amoebae. In: Unden, Gottfried; Thines, Eckhard; Schuffler, Anja. Host - Pathogen Interaction: Microbial Metabolism, Pathogenicity and Antiinfectives. Weinheim: Wiley-Blackwell, 139-152.

Schell, Ursula; Simon, Sylvia; Hilbi, Hubert (2016). Inflammasome recognition and regulation of the legionella flagellum. Current topics in microbiology and immunology, 397:161-181.

Tobias, Nicholas J; Ahrendt, Tilman; Schell, Ursula; Miltenberger, Melissa; Hilbi, Hubert; Bode, Helge B (2016). Legionella shows a diverse secondary metabolism dependent on a broad spectrum Sfp-type phosphopantetheinyl transferase. PeerJ, 4:e2720.

Häuslein, Ina; Manske, Christian; Goebel, Werner; Eisenreich, Wolfgang; Hilbi, Hubert (2016). Pathway analysis using (13) C-glycerol and other carbon tracers reveals a bipartite metabolism of Legionella pneumophila. Molecular Microbiology, 100(2):229-246.

Quiblier, Chantal; Jetter, Marion; Rominski, Mark; Mouttet, Forouhar; Böttger, Erik C; Keller, Peter M; Hombach, Michael (2016). Performance of copan WASP for routine urine microbiology. Journal of Clinical Microbiology, 54(3):585-592.

Fascellaro, Giuseppina. Phenotypic and proteomic characterization of M. smegmatis pup deletion mutant in the context of stress conditions. 2016, University of Zurich, Faculty of Science.

Thanabalasingam, Arjun. Speziesidentifizierung von Staphylokokken: Vergleich des massenspektrometrischen MALDI Biotyper Systems mit dem biochemischen Automaten Vitek 2. 2016, University of Zurich, Faculty of Medicine.

Schell, Ursula; Simon, Sylvia; Sahr, Tobias; Hager, Dominik; Albers, Michael F; Kessler, Aline; Fahrnbauer, Felix; Trauner, Dirk; Hedberg, Christian; Buchrieser, Carmen; Hilbi, Hubert (2016). The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signaling and gene expression of Legionella pneumophila. Molecular Microbiology, 99(4):778-793.

Bauerfeind, Rolf; von Graevenitz, Alexander; Kimmig, Peter; Schiefer, Hans Gerd; Schwarz, Tino; Slenczka, Werner; Zahner, Horst (2016). Zoonoses: infectious diseases transmissible from animals to humans (4th edition). Washington DC: ASM Press.

Sidler, Fabian. Übersicht der isolierten Corynebacterium spp. des Universitätsspitals Zürich (1997-2016). 2016, University of Zurich, Faculty of Medicine.

2015

Hombach, Michael; von Gunten, Barbara; Castelberg, Claudio; Bloemberg, Guido V (2015). Evaluation of the Rapidec Carba NP test for detection of Carbapenemases in Enterobacteriaceae. Journal of Clinical Microbiology, 53(12):3828-2833.

Simon, Sylvia; Schell, Ursula; Heuer, Natalie; Hager, Dominik; Albers, Michael F; Matthias, Jan; Fahrnbauer, Felix; Trauner, Dirk; Eichinger, Ludwig; Hedberg, Christian; Hilbi, Hubert (2015). Inter-kingdom signaling by the Legionella Quorum Sensing Molecule LAI-1 modulates cell migration through an IQGAP1-Cdc42-ARHGEF9-dependent pathway. PLoS Pathogens, 11(12):e1005307.

Hombach, Michael; Maurer, Florian P; Pfiffner, Tamara; Böttger, Erik C; Furrer, Reinhard (2015). Standardization of operator-dependent variables affecting precision and accuracy of the disk diffusion method for antibiotic susceptibility testing. Journal of Clinical Microbiology, 53(12):3864-3869.

Bloemberg, Guido V; Keller, Peter M; Stucki, David; Trauner, Andrej; Borrell, Sonia; Latshang, Tsogyal; Coscolla, Mireia; Rothe, Thomas; Hömke, Rico; Ritter, Claudia; Feldmann, Julia; Schulthess, Bettina; Gagneux, Sebastien; Böttger, Erik C (2015). Acquired Resistance to Bedaquiline and Delamanid in Therapy for Tuberculosis. New England Journal of Medicine, 373(20):1986-1988.

Zbinden, Andrea; Zbinden, Reinhard; Berger, Christoph; Arlettaz, Romaine (2015). Case series of bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology, 107(1):56-59.

Bevilacqua, Nazario; Nicastri, Emanuele; Chinello, Pierangelo; Puro, Vincenzo; Petrosillo, Nicola; Di Caro, Antonino; Capobianchi, Maria Rosaria; Lanini, Simone; Vairo, Francesco; Pletschette, Michel; Zumla, Alimuddin; Ippolito, Giuseppe (2015). Criteria for discharge of patients with Ebola virus diseases in high-income countries. The Lancet Global Health, 3(12):e739-e740.

Kohler, Philipp; Kuster, Stefan P; Bloemberg, Guido; Schulthess, Bettina; Frank, Michelle; Tanner, Felix C; Rössle, Matthias; Böni, Christian; Falk, Volkmar; Wilhelm, Markus J; Sommerstein, Rami; Achermann, Yvonne; Ten Oever, Jaap; Debast, Sylvia B; Wolfhagen, Maurice J H M; Brandon Bravo Bruinsma, George J; Vos, Margreet C; Bogers, Ad; Serr, Annerose; Beyersdorf, Friedhelm; Sax, Hugo; Böttger, Erik C; Weber, Rainer; van Ingen, Jakko; Wagner, Dirk; Hasse, Barbara (2015). Healthcare-associated prosthetic heart valve, aortic vascular graft, and disseminated Mycobacterium chimaera infections subsequent to open heart surgery. European Heart Journal, 36(40):2745-2753.

Imkamp, Frank; Ziemski, Michal; Weber-Ban, Eilika (2015). Pupylation-dependent and -independent proteasomal degradation in mycobacteria. BioMolecular Concepts, 6(4):285-301.

Kaufmann, S H E; Bloom, B; Brosch, R; Cardona, P-J; Dockrell, H; Fritzell, B; Grode, L; Hanekom, W; Hokey, D; Levin, M; Martin, C; Sander, P; Scriba, T; Shaligram, U; Tameris, M; von Reyn, F; Walker, B; Weiner, J; White, R G; Schrager, L (2015). Developing whole mycobacteria cell vaccines for tuberculosis: Workshop proceedings, Max Planck Institute for Infection Biology, Berlin, Germany, July 9, 2014. Vaccine, 33(26):3047-3055.

Valsesia, Giorgia; Roos, Malgorzata; Böttger, Erik C; Hombach, Michael (2015). A statistical approach for determination of disk diffusion-based cutoff values for systematic characterization of wild-type and non-wild-type bacterial populations in antimicrobial susceptibility testing. Journal of Clinical Microbiology, 53(6):1812-1822.

Lanini, Simone; Zumla, Alimuddin; Ioannidis, John P A; Di Caro, Antonino; Krishna, Sanjeev; Gostin, Lawrence; Girardi, Enrico; Pletschette, Michel; Strada, Gino; Baritussio, Aldo; Portella, Gina; Apolone, Giovanni; Cavuto, Silvio; Satolli, Roberto; Kremsner, Peter; Vairo, Francesco; Ippolito, Giuseppe (2015). Are adaptive randomised trials or non-randomised studies the best way to address the Ebola outbreak in west Africa? Lancet Infectious Diseases, 15(6):738-745.

Valsesia, Giorgia; Hombach, Michael; Maurer, Florian P; Courvalin, Patrice; Roos, Malgorzata; Böttger, Erik C (2015). The Resistant-Population Cutoff (RCOFF): a new concept for improved characterization of antimicrobial susceptibility patterns of non-wild-type bacterial populations. Journal of Clinical Microbiology, 53(6):1806-1811.

Matsushita, Takahiko; Chen, Weiwei; Juskeviciene, Reda; Teo, Youjin; Shcherbakov, Dimitri; Vasella, Andrea; Böttger, Erik C; Crich, David (2015). Influence of 4'-O-Glycoside Constitution and Configuration on Ribosomal Selectivity of Paromomycin. Journal of the American Chemical Society, 137(24):7706-7717.

Bruhn, David F; Waidyarachchi, Samanthi L; Madhura, Dora B; Shcherbakov, Dimitri; Zheng, Zhong; Liu, Jiuyu; Abdelrahman, Yasser M; Singh, Aman P; Duscha, Stefan; Rathi, Chetan; Lee, Robin B; Belland, Robert J; Meibohm, Bernd; Rosch, Jason W; Böttger, Erik C; Lee, Richard E (2015). Aminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infections. Science Translational Medicine, 7(288):288ra75.

Bukowska, Magdalena A; Hohl, Michael; Geertsma, Eric R; Hürlimann, Lea M; Grütter, Markus G; Seeger, Markus A (2015). A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter. Biochemistry, 54(19):3086-3099.

Sahrmann, P; Manz, A; Attin, T; Zbinden, R; Schmidlin, P R (2015). Effect of application of a PVP-iodine solution before and during subgingival ultrasonic instrumentation on post-treatment bacteremia: A randomized single-center placebo-controlled clinical trial. Journal of Clinical Periodontology, 42(7):632-639.

Keller, Peter M; Hömke, Rico; Ritter, Claudia; Valsesia, Giorgia; Bloemberg, Guido V; Böttger, Erik C (2015). Determination of MIC Distribution and Epidemiological Cut-Off Values for Bedaquiline and Delamanid in Mycobacterium tuberculosis Using MGIT 960/TB eXiST. Antimicrobial Agents and Chemotherapy, 59(7):4352-4355.

Maurer, Florian P; Bruderer, Vera L; Castelberg, Claudio; Ritter, Claudia; Scherbakov, Dimitri; Bloemberg, Guido V; Böttger, Erik C (2015). Aminoglycoside-modifying enzymes determine the innate susceptibility to aminoglycoside antibiotics in rapidly growing mycobacteria. Journal of Antimicrobial Chemotherapy, 70(5):1412-1419.

Finsel, Ivo; Hilbi, Hubert (2015). Formation of a pathogen vacuole according to Legionella pneumophila: how to kill one bird with many stones. Cellular Microbiology, 17(7):935-950.

Harrison, Christopher F; Kicka, Sébastien; Kranjc, Agata; Finsel, Ivo; Chiriano, Gianpaolo; Ouertatani-Sakouhi, Hajer; Soldati, Thierry; Scapozza, Leonoardo; Hilbi, Hubert (2015). Adrenergic antagonists restrict replication of Legionella. Microbiology, 161(7):1392-1406.

Jeschke, Andreas; Zehethofer, Nicole; Lindner, Buko; Krupp, Jessica; Schwudke, Dominik; Haneburger, Ina; Jovic, Marko; Backer, Jonathan M; Balla, Tamas; Hilbi, Hubert; Haas, Albert (2015). Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis. Proceedings of the National Academy of Sciences of the United States of America, 112(15):4636-4641.

Mueller, N J; Tini, G M; Weber, A; Gaspert, A; Husmann, L; Bloemberg, G; Boehler, A; Benden, C (2015). Hepatitis From Spiroplasma sp. in an Immunocompromised Patient. American Journal of Transplantation, 15(9):2511-2516.

Harrison, C F; Chiriano, G; Finsel, I; Manske, C; Hoffmann, C; Steiner, B; Kranjc, A; Patthey-Vuadens, O; Kicka, S; Trofimov, V; Ouertatani-Sakouhi, H; Soldati, T; Scapozza, L; Hilbi, H (2015). Amoebae-based screening reveals a novel family of compounds restricting intracellular Legionella. ACS Infectious Diseases, 1(7):327-338.

Sax, Hugo; Bloemberg, Guido; Hasse, Barbara; Sommerstein, Rami; Kohler, Philipp; Achermann, Yvonne; Rössle, Matthias; Falk, Volkmar; Kuster, Stefan P; Böttger, Erik C; Weber, Rainer (2015). Prolonged Outbreak of Mycobacterium chimaera Infection After Open-Chest Heart Surgery. Clinical Infectious Diseases, 61(1):67-75.

Sander, Peter; Clark, Simon; Petrera, Agnese; Vilaplana, Cristina; Meuli, Michael; Selchow, Petra; Zelmer, Andrea; Mohanan, Deepa; Andreu, Nuria; Rayner, Emma; Dal Molin, Michael; Bancroft, Gregory J; Johansen, Pål; Cardona, Pere-Joan; Williams, Ann; Böttger, Erik C (2015). Deletion of zmp1 improves Mycobacterium bovis BCG-mediated protection in a guinea pig model of tuberculosis. Vaccine, 33(11):1353-1359.

Cambau, E; Viveiros, M; Machado, D; Raskine, L; Ritter, C; Tortoli, E; Matthys, V; Hoffner, S; Richter, E; Perez Del Molino, M L; Cirillo, D M; van Soolingen, D; Böttger, E C (2015). Revisiting susceptibility testing in MDR-TB by a standardized quantitative phenotypic assessment in a European multicentre study. Journal of Antimicrobial Chemotherapy, 70(3):686-696.

Mandhapati, Appi Reddy; Kato, Takayuki; Matsushita, Takahiko; Ksebati, Bashar; Vasella, Andrea; Böttger, Erik C; Crich, David (2015). Fluorine-decoupled carbon spectroscopy for the determination of configuration at fully substituted, trifluoromethyl- and perfluoroalkyl-bearing carbons: comparison with 19F-1H heteronuclear Overhauser effect spectroscopy. Journal of Organic Chemistry, 80(3):1754-1763.

Somoskovi, Akos; Bruderer, Vera; Hömke, Rico; Bloemberg, Guido V; Böttger, Erik C (2015). A mutation associated with clofazimine and bedaquiline cross-resistance in MDR-TB following bedaquiline treatment. European Respiratory Journal, 45(2):554-557.

Zbinden, R (2015). Aggregatibacter, Capnocytophaga, Eikenella, Kingella, Pasteurella, and other fastidious or rarely encountered Gram-negative rods. In: Jorgensen, J H; Pfaller, M A; Carroll, K C; Funke, G; Landry, M L; Richter, S S; Warnock, D W. Manual of Clinical Microbiology. Washington DC: ASM Press Washington DC USA, 652-666.

Duscha, Stefan. Aminoglycoside-induced mistranslation and its consequences in higher eukaryotic cells. 2015, University of Zurich, Faculty of Science.

Marino, Jacopo; Hohl, Michael; Seeger, Markus A; Zerbe, Oliver; Geertsma, Eric (2015). Bicistronic mRNAs to enhance membrane protein overexpression. Journal of Molecular Biology, 427:943-953.

Seidl, Kati; Leimer, Nadja; Palheiros Marques, Miguel; Furrer, Alexandra; Holzmann-Bürgel, Anne; Senn, Gabriela; Zbinden, Reinhard; Zinkernagel, Annelies S (2015). Clonality and antimicrobial susceptibility of methicillin-resistant Staphylococcus aureus at the University Hospital Zurich, Switzerland between 2012 and 2014. Annals of Clinical Microbiology and Antimicrobials, 14(14):online.

Maurer, Florian P; Castelberg, Claudio; Quiblier, Chantal; Bloemberg, Guido V; Hombach, Michael (2015). Evaluation of carbapenemase screening and confirmation tests in Enterobacteriaceae and development of a practical diagnostic algorithm. Journal of Clinical Microbiology, 53(1):95-104.

Bruhn, David F; Scherman, Michael S; Liu, Jiuyu; Scherbakov, Dimitri; Meibohm, Bernd; Böttger, Erik C; Lenaerts, Anne J; Lee, Richard E (2015). In vitro and in vivo evaluation of synergism between anti-tubercular spectinamides and non-classical tuberculosis antibiotics. Scientific Reports, 5:13985.

Gamma, Thomas. Molekulare Identifizierung von Corynebakterien 1993-1999. 2015, University of Zurich, Faculty of Medicine.

Herweg, Jo-Ana; Hansmeier, Nicole; Otto, Andreas; Geffken, Anna C; Subbarayal, Prema; Prusty, Bhupesh K; Becher, Dörte; Hensel, Michael; Schaible, Ulrich E; Rudel, Thomas; Hilbi, Hubert (2015). Purification and proteomics of pathogen-modified vacuoles and membranes. Frontiers in Cellular and Infection Microbiology, 5:48.

Meyer, Martin Dominique. Ribosomal accuracy in higher eukaryotes – mistranslation and unfolded protein response. 2015, University of Zurich, Faculty of Science.

Simon, Sylvia; Hilbi, Hubert (2015). Subversion of cell-autonomous immunity and cell migration by Legionella pneumophila effectors. Frontiers in Immunology, 6:447.

Kato, T; Yang, G; Teo, Y; Juskeviciene, R; Perez-Fernandez, D; Shinde, H M; Salian, S; Bernet, B; Vasella, A; Böttger, E C; Crich, D (2015). Synthesis and antiribosomal activities of 4′-O-, 6′-O-, 4″-O-, 4′,6′-O- and 4″,6″-O-derivatives in the kanamycin series indicate differing target selectivity patterns between the 4,5- and 4,6-series of disubstituted 2-deoxystreptamine aminoglycoside antibiotics. ACS Infectious Diseases, 1(10):479-486.

Hombach, Michael. The importance of diagnostic algorithms and standardized methods of antimicrobial susceptibility testing for drug susceptibility categorization and clinical breakpoint setting. 2015, University of Zurich, Faculty of Medicine.

Oishi, Naoki; Duscha, Stefan; Boukari, Heithem; Meyer, Martin; Xie, Jing; Wei, Gao; Schrepfer, Thomas; Roschitzki, Bernd; Böttger, Erik C; Schacht, Jochen (2015). XBP1 mitigates aminoglycoside-induced endoplasmic reticulum stress and neuronal cell death. Cell Death and Disease, 6(e1763):online.

2014

Weber, Stephen; Stirnimann, Christian U; Wieser, Mara; Frey, Daniel; Meier, Roger; Engelhardt, Sabrina; Li, Xiaodan; Capitani, Guido; Kammerer, Richard A; Hilbi, Hubert (2014). A type IV translocated Legionella cysteine phytase counteracts intracellular growth restriction by phytate. Journal of Biological Chemistry, 289(49):34175-34188.

Büchler, Andrea C; Rampini, Silvana K; Stelling, Simon; Ledergerber, Bruno; Peter, Silke; Schweiger, Alexander; Ruef, Christian; Zbinden, Reinhard; Speck, Roberto F (2014). Antibiotic susceptibility of Clostridium difficile is similar worldwide over two decades despite widespread use of broad-spectrum antibiotics: an analysis done at the University Hospital of Zurich. BMC Infectious Diseases, 14:607.

Meyer, Martin; Freihofer, Pietro; Scherman, Michael; Teague, Joanne; Lenaerts, Anne; Böttger, Erik C (2014). In vivo efficacy of apramycin in murine infection models. Antimicrobial Agents and Chemotherapy, 58(11):6938-6941.

Maurer, Florian P; Courvalin, Patrice; Böttger, Erik C; Hombach, Michael (2014). Integrating forecast probabilities in antibiograms: a way to guide antimicrobial prescriptions more reliably? Journal of Clinical Microbiology, 52(10):3674-3684.

Wennerås, Christine; Bloemberg, Guido; Bogdan, Christian (2014). Reply to Raoult. Clinical Infectious Diseases, 59(7):1042-1043.

Mandhapati, Appi Reddy; Shcherbakov, Dimitri; Duscha, Stefan; Vasella, Andrea; Böttger, Erik C; Crich, David (2014). Importance of the 6'-hydroxy group and its configuration for apramycin activity. ChemMedChem, 9(9):2074-2083.

Schulthess, Bettina; Ledermann, Raphael; Mouttet, Forouhar; Zbinden, Andrea; Bloemberg, Guido V; Böttger, Erik C; Hombach, Michael (2014). Use of the Bruker MALDI Biotyper for identification of molds in the clinical mycology laboratory. Journal of Clinical Microbiology, 52(8):2797-2803.

Hohl, Michael; Hürlimann, Lea M; Böhm, Simon; Schöppe, Jendrik; Grütter, Markus G; Bordignon, Enrica; Seeger, Markus A (2014). Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Proceedings of the National Academy of Sciences of the United States of America, 111(30):11025-11030.

Hilbi, Hubert; Rothmeier, Eva; Hoffmann, Christine; Harrison, Christopher F (2014). Beyond Rab GTPases Legionella activates the small GTPase Ran to promote microtubule polymerization, pathogen vacuole motility, and infection. Small GTPases, 5(3):online.

Maurer, Florian P; Bruderer, Vera L; Ritter, Claudia; Castelberg, Claudio; Bloemberg, Guido V; Böttger, Erik C (2014). Lack of antimicrobial bactericidal activity in Mycobacterium abscessus. Antimicrobial Agents and Chemotherapy, 58(7):3828-3836.

Hombach, Michael; Courvalin, Patrice; Böttger, Erik C (2014). Validation of antibiotic susceptibility testing guidelines in a routine clinical microbiology laboratory exemplifies general key challenges in setting clinical breakpoints. Antimicrobial Agents and Chemotherapy, 58(7):3921-3926.

Kolm, Isabel; Aceto, Leonardo; Hombach, Michael; Kamarshev, Jivko; Hafner, Jurg; Urosevic-Maiwald, Mirjana (2014). Cervicofacial actinomycosis: a long forgotten infectious complication of immunosuppression - report of a case and review of the literature. Dermatology Online Journal, 20(5):22640.

Perez-Fernandez, Déborah; Shcherbakov, Dmitri; Matt, Tanja; Leong, Ng Chyan; Kudyba, Iwona; Duscha, Stefan; Boukari, Heithem; Patak, Rashmi; Dubbaka, Srinivas Reddy; Lang, Kathrin; Meyer, Martin; Akbergenov, Rashid; Freihofer, Pietro; Vaddi, Swapna; Thommes, Pia; Ramakrishnan, V; Vasella, Andrea; Böttger, Erik C (2014). 4'-O-substitutions determine selectivity of aminoglycoside antibiotics. Nature Communications, 5:3112.

Bloemberg, Guido Vincent. An essential role for the 16S rRNA gene in the identification of culture negative infections and the discovery of novel human associated pathogens. 2014, University of Zurich, Faculty of Medicine.

Khatri, Bhagwati; Whelan, Adam; Clifford, Derek; Petrera, Agnese; Sander, Peter; Vordermeier, H Martin (2014). BCG Δzmp1 vaccine induces enhanced antigen specific immune responses in cattle. Vaccine, 32(7):779-784.

Orasch, Christina; Marchetti, Oscar; Garbino, Jorge; Schrenzel, Jacques; Zimmerli, Stefan; Mühlethaler, Konrad; Rossi, Marco; Pfyffer, Gaby; Ruef, Christian; Fehr, Jan; Zbinden, Reinhard; Calandra, Thierry; Bille, Jacques (2014). Candida species distribution and antifungal susceptibility testing according to European Committee on Antimicrobial Susceptibility Testing and new vs. old Clinical and Laboratory Standards Institute clinical breakpoints: a 6-year prospective candidaemia survey from the fungal infection network of Switzerland. Clinical Microbiology and Infection, 20(7):698-705.

Zbinden, Andrea; Quiblier, Chantal; Hernandez, David; Herzog, Kathrin; Bodler, Paul; Senn, Maria M; Gizard, Yann; Schrenzel, Jacques; François, Patrice (2014). Characterization of Streptococcus tigurinus Small-Colony Variants Causing Prosthetic Joint Infection by Comparative Whole-Genome Analyses. Journal of Clinical Microbiology, 52(2):467-474.

Sim, Jae Hoon; Xie, Youzhou; Karamuk, Erdal; von Kameke, Alexander; Holder, Jens Ten; Zbinden, Reinhard; Röösli, Christof; Huber, Alexander M (2014). Clinical and microbiological evaluation of an extended-wear hearing instrument. Audiology and Neurotology. Extra, 4(2):32-45.

Eicher, Thomas; Seeger, Markus A; Anselmi, Claudio; Zhou, Wenchang; Brandstätter, Lorenz; Verrey, François; Diederichs, Kay; Faraldo-Gómez, José D; Pos, Klaas M (2014). Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB. Cambridge UK: eLife Sciences Publications Ltd..

Glatz, Martin; Müllegger, Robert R; Maurer, Florian; Fingerle, Volker; Achermann, Yvonne; Wilske, Bettina; Bloemberg, Guido V (2014). Detection of Candidatus Neoehrlichia mikurensis, Borrelia burgdorferi sensu lato genospecies and Anaplasma phagocytophilum in a tick population from Austria. Ticks and Tick-borne Diseases, 5(2):139-144.

Mori, Mattia; Moraca, Francesca; Deodato, Davide; Ferraris, Davide M; Selchow, Petra; Sander, Peter; Rizzi, Menico; Botta, Maurizio (2014). Discovery of the first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor. Bioorganic & Medicinal Chemistry Letters, 24(11):2508-2511.

Maurer, Florian P; Castelberg, Claudio; Quiblier, Chantal; Böttger, Erik C; Somoskövi, Akos (2014). Erm(41)-dependent inducible resistance to azithromycin and clarithromycin in clinical isolates of Mycobacterium abscessus. Journal of Antimicrobial Chemotherapy, 69(6):1559-1563.

Bloemberg, Guido V; Polsfuss, Silke; Meyer, Vera; Böttger, Erik C; Hombach, Michael (2014). Evaluation of the AID ESBL line probe assay for rapid detection of extended-spectrum β-lactamase (ESBL) and KPC carbapenemase genes in Enterobacteriaceae. Journal of Antimicrobial Chemotherapy, 69(1):85-90.

Ritter, C; Lucke, K; Sirgel, F A; Warren, R W; van Helden, P D; Böttger, E C; Bloemberg, G V (2014). Evaluation of the AID TB Resistance Line Probe Assay for Rapid Detection of Genetic Alterations Associated with Drug Resistance in Mycobacterium tuberculosis Strains. Journal of Clinical Microbiology, 52(3):940-946.

Schulthess, Bettina; Bloemberg, Guido V; Zbinden, Reinhard; Böttger, Erik C; Hombach, Michael (2014). Evaluation of the Bruker MALDI Biotyper for identification of Gram-positive rods - development of a diagnostic algorithm for the clinical laboratory. Journal of Clinical Microbiology, 52(4):1089-1097.

Zbinden, Andrea; Aras, Fatma; Zbinden, Reinhard; Mouttet, Forouhar; Schmidlin, Patrick R; Bloemberg, Guido V; Bostanci, Nagihan (2014). Frequent detection of Streptococcus tigurinus in the human oral microbial flora by a specific 16S rRNA gene real-time TaqMan PCR. BMC Microbiology, 14:231.

Roditscheff, Anna. Generation of a Mycobacterium smegmatis ΔOP0063 mutant and its genetic complementation. 2014, University of Zurich, Faculty of Science.

Steffen, Timothy. Generation of unmarked and marked suicide vectors for targeted deletion of Mycobacterium tuberculosis Rv3242c and Rv2346c (esxO) genes. 2014, University of Zurich, Faculty of Science.

Wijnands, Charissa. Generation of vectors for targeted gene inactivation of he putative antibiotic resistance genes blaMab and arr in Mycobacterium abscessus. 2014, University of Zurich, Faculty of Science.

Simon, Sylvia; Wagner, Maria A; Rothmeier, Eva; Müller-Taubenberger, Annette; Hilbi, Hubert (2014). Icm/Dot-dependent inhibition of phagocyte migration by Legionella is antagonized by a translocated Ran GTPase activator. Cellular Microbiology, 16(7):977-992.

Duscha, Stefan; Boukari, Heithem; Shcherbakov, Dimitri; Salian, Sumantha; Silva, Sandrina; Kendall, Ann; Kato, Takayuki; Akbergenov, Rashid; Perez-Fernandez, Deborah; Bernet, Bruno; Vaddi, Swapna; Thommes, Pia; Schacht, Jochen; Crich, David; Vasella, Andrea; Böttger, Erik C (2014). Identification and evaluation of improved 4'-O-(alkyl) 4,5-disubstituted 2-deoxystreptamines as next-generation aminoglycoside antibiotics. mBio, 5(5):e01827-e01814.

Grankvist, Anna; Andersson, Per-Ola; Mattsson, Mattias; Sender, Monica; Vaht, Krista; Höper, Linnea; Sakiniene, Egidija; Trysberg, Estelle; Stenson, Martin; Fehr, Jan; Pekova, Sona; Bogdan, Christian; Bloemberg, Guido; Wennerås, Christine (2014). Infections with the tick-borne bacterium "Candidatus Neoehrlichia mikurensis" mimic noninfectious conditions in patients with B cell malignancies or autoimmune diseases. Clinical Infectious Diseases, 58(12):1716-1722.

Kölliker, Ramona. Infektionsschutz und Hygiene in der Zahnmedizin unter Berücksichtigung der Struktur der Mikroorganismen. 2014, University of Zurich, Faculty of Medicine.

Weber, Stephen; Hilbi, Hubert (2014). Live cell imaging of phosphoinositide dynamics during Legionella infection. Methods in Molecular Biology, 1197:153-167.

Medizinische Mikrobiologie (13. Auflage). Edited by: Kayser, F H; Böttger, E C; Deplazes, P; Haller, O; Roers, A (2014). Stuttgart: Georg Thieme Verlag.

Manske, Christian; Hilbi, Hubert (2014). Metabolism of the vacuolar pathogen Legionella and implications for virulence. Frontiers in Cellular and Infection Microbiology:4:125.

Meyer Sauteur, Patrick M; Relly, Christa; Hackenberg, Annette; Stahr, Nikolai; Berger, Christoph; Bloemberg, Guido V; Jacobs, Enno; Nadal, David (2014). Mycoplasma pneumoniae intrathecal antibody responses in bickerstaff brain stem encephalitis. Neuropediatrics, 45(01):061-063.

Aras, Fatma. Nachweis von Streptococcus tigurinus in der Mundflora bei verschiedenen Patienten des Zentrums für Zahnmedizin Zürich. 2014, University of Zurich, Faculty of Medicine.

Lepore, Marco; Kalinicenko, Artem; Colone, Alessia; Paleja, Bhairav; Singhal, Amit; Tschumi, Andreas; Lee, Bernett; Poidinger, Michael; Zolezzi, Francesca; Quagliata, Luca; Sander, Peter; Newell, Evan; Bertoletti, Antonio; Terracciano, Luigi; De Libero, Gennaro; Mori, Lucia (2014). Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire. Nature Communications, 5:3866.

Schell, Ursula; Kessler, Aline; Hilbi, Hubert (2014). Phosphorylation signalling through the Legionella quorum sensing histidine kinases LqsS and LqsT converges on the response regulator LqsR. Molecular Microbiology, 92(5):1039-1055.

Maurer, F; Castelberg, C; von Braun, A; Wolfensberger, A; Bloemberg, G; Bottger, E; Somoskovi, A (2014). Postsurgical wound infections due to rapidly growing mycobacteria in Swiss medical tourists following cosmetic surgery in Latin America between 2012 and 2014. Eurosurveillance, 19(37):pii=20905.

Striebel, Frank; Imkamp, Frank; Ozcelik, Dennis; Weber-Ban, Eilika (2014). Pupylation as a signal for proteasomal degradation in bacteria. Biochimica Et Biophysica Acta, 1843(1):103-113.

Somoskovi, Akos; Bloemberg, Guido V (2014). Reply to "Described Diagnostic Inconsistencies Were Observed with an Obsolete Version of the Xpert MTB/RIF Assay and Are Unlikely To Recur in the Current Version of the Assay". Journal of Clinical Microbiology, 52(2):705.

Deggim, Vanessa; Somoskovi, Akos; Bloemberg, Guido (2014). Reply to "Performance of the Xpert MTB/RIF Assay on Nonrespiratory Specimens and Accuracy of This Assay for Detection of Rifampin Resistance in a Low-Prevalence Setting". Journal of Clinical Microbiology, 52(2):707.

Lee, Richard E; Hurdle, Julian G; Liu, Jiuyu; Bruhn, David F; Matt, Tanja; Scherman, Michael S; Vaddady, Pavan K; Zheng, Zhong; Qi, Jianjun; Akbergenov, Rashid; Das, Sourav; Madhura, Dora B; Rathi, Chetan; Trivedi, Ashit; Villellas, Cristina; Lee, Robin B; Rakesh, Rakesh; Waidyarachchi, Samanthi L; Sun, Dianqing; McNeil, Michael R; Ainsa, Jose A; Boshoff, Helena I; Gonzalez-Juarrero, Mercedes; Meibohm, Bernd; Böttger, Erik C; Lenaerts, Anne J (2014). Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux. Nature Medicine, 20(2):152-158.

Brülle, Juliane K. Structural analysis of lipoprotein modifications in mycobacteria and other GC-rich Gram-positive bacteria. 2014, University of Zurich, Faculty of Science.

Meyer Sauteur, Patrick M; Bleisch, Barbara; Voit, Antje; Maurer, Florian P; Relly, Christa; Berger, Christoph; Nadal, David; Bloemberg, Guido V (2014). Survey of macrolide-resistant Mycoplasma pneumoniae in children with community-acquired pneumonia in Switzerland. Swiss Medical Weekly, 144:w14041.

Chen, Weiwei; Matsushita, Takahiko; Shcherbakov, Dimitri; Boukari, Heithem; Vasella, Andrea; Böttger, Erik C; Crich, David (2014). Synthesis, antiribosomal and antibacterial activity of 4'-O-glycopyranosyl paromomycin aminoglycoside antibiotics. MedChemComm, 5:1179-1187.

Dolinsky, Stephanie; Haneburger, Ina; Cichy, Adam; Hannemann, Mandy; Itzen, Aymelt; Hilbi, Hubert (2014). The Legionella longbeachae Icm/Dot substrate SidC selectively binds phosphatidylinositol 4-phosphate with nanomolar affinity and promotes pathogen vacuole-endoplasmic reticulum interactions. Infection and Immunity, 82(10):4021-4033.

Somoskovi, A; Helbling, P; Deggim, V; Hömke, R; Ritter, C; Böttger, E C (2014). Transmission of multidrug-resistant tuberculosis in a low-incidence setting, Switzerland, 2006 to 2012. Eurosurveillance, 19(11):4.

von Graevenitz, A; Funke, G (2014). Turicella otitidis and Corynebacterium auris: 20 years on. Infection, 42(1):1-4.

2013

Maurer, Florian P; Maggio, Ewerton M; Roth, Thomas N; Kuster, Stefan P; Bloemberg, Guido V (2013). A well-preserved culprit. Clinical Infectious Diseases, 56(5):747-748.

de Melo Oliveira, Maria G; Abels, Susanne; Zbinden, Reinhard; Bloemberg, Guido V; Zbinden, Andrea (2013). Accurate identification of fastidious Gram-negative rods: integration of both conventional phenotypic methods and 16S rRNA gene analysis. BMC Microbiology, 13:162.

Broecker, Felix; Kube, Michael; Klumpp, Jochen; Schuppler, Markus; Biedermann, Luc; Hecht, Jochen; Hombach, Michael; Keller, Peter M; Rogler, Gerhard; Moelling, Karin (2013). Analysis of the intestinal microbiome of a recovered clostridium difficile patient after fecal transplantation. Digestion, 88(4):243-251.

Schmidig, K. Antibikrobielle Wirkung von Probiotika gegen uropathogene Keime. 2013, University of Zurich, Faculty of Medicine.

Dillinger, Daniel. Auswertung der USZ-Blutkulturisolatstatistik (1989-2011). 2013, University of Zurich, Faculty of Medicine.

Fulchini, Rosamaria; Bloemberg, Guido; Boggian, Katia (2013). Bacillary angiomatosis and bacteremia due to bartonella quintana in a patient with chronic lymphocytic leukemia. Case Reports in Infectious Diseases, 2013:694765.

Tokuda, H; Sander, P; Lee, B; Okuda, S; Grau, T; Tschumi, A; Brülle, J K; Kurokawa, K; Nakayama, H (2013). Bacterial lipoproteins: biogenesis, virulence/pathogenicity and trafficking. In: Remaut, H; Fronzes, R. Bacterial membranes : Structural and molecular biology. s.n.: Horizon Scientific Press, Ch. 4.

Wolfensberger, Aline; Sax, Hugo; Weber, Rainer; Zbinden, Reinhard; Kuster, Stefan P; Hombach, Michael (2013). Change of antibiotic susceptibility testing guidelines from CLSI to EUCAST: Influence on cumulative hospital antibiograms. PLoS ONE, 8(11):e79130.

Maurer, Florian P; Keller, Peter M; Beuret, Christian; Joha, Cornelia; Achermann, Yvonne; Gubler, Jaques; Bircher, Daniela; Karrer, Urs; Fehr, Jan; Zimmerli, Lukas; Bloemberg, Guido V (2013). Close geographic association of human neoehrlichiosis and tick populations carrying Candidatus Neoehrlichia mikurensis in Eastern Switzerland. Journal of clinical microbiology, 51(1):169-176.

Das Graças de Melo Oliveira, Maria. Comparison of conventional and molecular methods for identification of fastidious Gram-negative rods in the clinical laboratory. 2013, University of Zurich, Faculty of Medicine.

Hombach, Michael; Mouttet, Brice; Bloemberg, Guido V (2013). Consequences of revised CLSI and EUCAST guidelines for antibiotic susceptibility patterns of ESBL- and AmpC β-lactamase-producing clinical Enterobacteriaceae isolates. Journal of Antimicrobial Chemotherapy, 68(9):2092-2098.

Kovari, Helen; de Melo Oliveira, Maria D G; Hauser, Paula; Läuchli, Severin; Meyer, Jürg; Weber, Rainer; Zbinden, Reinhard (2013). Decreased susceptibility of Neisseria gonorrhoeae isolates from Switzerland to Cefixime and Ceftriaxone: antimicrobial susceptibility data from 1990 and 2000 to 2012. BMC Infectious Diseases, 13:603.

Roditscheff, Anna. Deletion of ESX-3MS secretion genes in Mycobacterium smgematis and complementation with ESX-3TB. 2013, University of Zurich, Faculty of Science.

Somoskovi, Akos; Deggim, Vanessa; Ciardo, Diana; Bloemberg, Guido V (2013). Diagnostic implications of inconsistent results obtained with the Xpert MTB/Rif assay in detection of Mycobacterium tuberculosis isolates with an rpoB mutation associated with low-level rifampin resistance. Journal of Clinical Microbiology, 51(9):3127-3129.

Mouttet, Brice. Differences in interpretation of antibiotic susceptibilities of ESBL strains using CLSI and EUCAST guidelines. 2013, University of Zurich, Faculty of Medicine.

Hombach, Michael; Somoskövi, Akos; Hömke, Rico; Ritter, Claudia; Böttger, Erik C (2013). Drug susceptibility distributions in slowly growing non-tuberculous mycobacteria using MGIT 960 TB eXiST. International Journal of Medical Microbiology : IJMM, 303(5):270-276.

Abubakar, Ibrahim; Zignol, Matteo; Falzon, Dennis; Raviglione, Mario; Ditiu, Lucica; Masham, Susan; Adetifa, Ifedayo; Ford, Nathan; Cox, Helen; Lawn, Stephen D; Marais, Ben J; McHugh, Timothy D; Mwaba, Peter; Bates, Matthew; Lipman, Marc; Zijenah, Lynn; Logan, Simon; McNerney, Ruth; Zumla, Adam; Sarda, Krishna; Nahid, Payam; Hoelscher, Michael; Pletschette, Michel; Memish, Ziad A; Kim, Peter; Hafner, Richard; Cole, Stewart; Migliori, Giovanni Battista; Maeurer, Markus; Schito, Marco; Zumla, Alimuddin (2013). Drug-resistant tuberculosis: time for visionary political leadership. Lancet Infectious Diseases, 13(6):529-539.

Manz, Andrea. Effekt der ultraschallgestützten Reinigung und Spülung von subgingivalen Wurzeloberflächen mit PVP-Jod auf die Bakteriämie infolge der Behandlung. 2013, University of Zurich, Faculty of Medicine.

Bloemberg, Guido V; Voit, Antje; Ritter, Claudia; Deggim, Vanessa; Böttger, Erik C (2013). Evaluation of Cobas TaqMan MTB for direct detection of the Mycobacterium tuberculosis complex in comparison with Cobas Amplicor MTB. Journal of Clinical Microbiology, 51(7):2112-2117.

Fenner, Lukas; Egger, Matthias; Bodmer, Thomas; Furrer, Hansjakob; Ballif, Marie; Battegay, Manuel; Helbling, Peter; Fehr, Jan; Gsponer, Thomas; Rieder, Hans L; Zwahlen, Marcel; Hoffmann, Matthias; Bernasconi, Enos; Cavassini, Matthias; Calmy, Alexandra; Dolina, Marisa; Frei, Reno; Janssens, Jean-Paul; Borrell, Sonia; Stucki, David; Schrenzel, Jacques; Böttger, Erik C; Gagneux, Sebastien (2013). HIV infection disrupts the sympatric host-pathogen relationship in human tuberculosis. PLoS Genetics, 9(3):e1003318.

Machado, Diana; Perdigão, João; Ramos, Jorge; Couto, Isabel; Portugal, Isabel; Ritter, Claudia; Boettger, Erik C; Viveiros, Miguel (2013). High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations. Journal of Antimicrobial Chemotherapy, 68(8):1728-1732.

Schulthess, Bettina; Brodner, Katharina; Bloemberg, Guido V; Zbinden, Reinhard; Böttger, Erik C; Hombach, Michael (2013). Identification of Gram-positive cocci by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry: comparison of different preparation methods and implementation of a practical algorithm for routine diagnostics. Journal of Clinical Microbiology, 51(6):1834-1840.

Hombach, Michael; Wolfensberger, Aline; Kuster, Stefan P; Böttger, Erik C (2013). Influence of clinical breakpoint changes from CLSI 2009 to EUCAST 2011 antimicrobial susceptibility testing guidelines on multidrug resistance rates of Gram-negative rods. Journal of Clinical Microbiology, 51(7):2385-2587.

Deggim, Vanessa; Somoskovi, Akos; Voit, Antje; Böttger, Erik C; Bloemberg, Guido V (2013). Integrating the Xpert MTB/RIF assay into a diagnostic workflow for rapid detection of Mycobacterium tuberculosis in a low-prevalence area. Journal of Clinical Microbiology, 51(7):2396-2399.

Marchesi, Martina. Investigating the impact of stress conditions on the expression of genes related to the mycobacterial Pup-proteasome system. 2013, University of Zurich, Faculty of Medicine.

Brülle, Juliane K; Tschumi, Andreas; Sander, Peter (2013). Lipoproteins of slow-growing Mycobacteria carry three fatty acids and are N-acylated by apolipoprotein N-acyltransferase BCG_2070c. BMC Microbiology, 13:223.

Waeckerle-Men, Ying; Bruffaerts, Nicolas; Liang, Yuan; Jurion, Fabienne; Sander, Peter; Kündig, Thomas M; Huygen, Kris; Johansen, Pål (2013). Lymph node targeting of BCG vaccines amplifies CD4 and CD8 T-cell responses and protection against Mycobacterium tuberculosis. Vaccine, 31(7):1057-1064.

Bächli, Patrick. Maldi-TOF MS Analyse von anaeroben Bakterien. 2013, University of Zurich, Faculty of Medicine.

Schacht, Jochen; Böttger, Erik C (2013). Mission accomplished. Science Translational Medicine:online.

Senn, L; Basset, P; Greub, G; Prod'hom, G; Frei, R; Zbinden, R; Gaia, V; Balmelli, C; Pfyffer, G E; Mühlemann, K; Zanetti, G; Blanc, D S (2013). Molecular epidemiology of methicillin-resistant Staphylococcus aureus in Switzerland: sampling only invasive isolates does not allow a representative description of the local diversity of clones. Clinical Microbiology and Infection, 19(7):E288-E290.

Gamma, Thomas. Molekulare Identifizierung von Corynebakterien, welche 1993-1999 konventionell nicht identifiziert werden konnten. 2013, University of Zurich, Faculty of Medicine.

Dengler, Vanina; McCallum, Nadine; Kiefer, Patrick; Christen, Philipp; Patrignani, Andrea; Vorholt, Julia A; Berger-Bächi, Brigitte; Senn, Maria M (2013). Mutation in the c-di-amp cyclase daca affects fitness and resistance of methicillin resistant staphylococcus aureus. PLoS ONE, 8(8):e73512.

Middendorp, Matthias. Nachweis von Antikörpern gegen Propionibacterium acnes bei Patienten mit pulmonaler Hypertonie und mit Endocarditis. 2013, University of Zurich, Faculty of Medicine.

Staufer, Niklas. Prevalence of mecA and PVL genes in MRSA strains from Switzerland. 2013, University of Zurich, Faculty of Medicine.

Achermann, Yvonne; Rössle, Matthias; Hoffmann, Matthias; Deggim, Vanessa; Kuster, Stefan; Zimmermann, Dieter R; Bloemberg, Guido; Hombach, Michael; Hasse, Barbara (2013). Prosthetic valve endocarditis and bloodstream infection due to Mycobacterium chimaera. Journal of Clinical Microbiology, 51(6):1769-1773.

Quiblier, Chantal; Seidl, Kati; Roschitzki, Bernd; Zinkernagel, Annelies S; Berger-Bächi, Brigitte; Senn, Maria M (2013). Secretome analysis defines the major role of SecDF in Staphylococcus aureus virulence. PLoS ONE, 8(5):e63513.

Hombach, Michael; Zbinden, Reinhard; Böttger, Erik C (2013). Standardisation of disk diffusion results for antibiotic susceptibility testing using the sirscan automated zone reader. BMC Microbiology, 13:225.

Chan, Yvonne G Y; Frankel, Matthew B; Dengler, Vanina; Schneewind, Olaf; Missiakas, Dominique (2013). Staphylococcus aureus mutants lacking the LytR-CpsA-Psr family of enzymes release cell wall teichoic acids into the extracellular medium. Journal of Bacteriology, 195(20):4650-4659.

Veloso, Tiago Rafael; Zbinden, Andrea; Andreoni, Federica; Giddey, Marlyse; Vouillamoz, Jacques; Moreillon, Philippe; Zinkernagel, Annelies Sophie; Entenza, José Manuel (2013). Streptococcus tigurinus is highly virulent in a rat model of experimental endocarditis. International Journal of Medical Microbiology : IJMM, 303(8):498-504.

Schöning, Janne Marie; Cerny, Nadine; Prohaska, Sarah; Wittenbrink, Max M; Smith, Noel H; Bloemberg, Guido; Pewsner, Mirjam; Schiller, Irene; Origgi, Francesco C; Ryser-Degiorgis, Marie-Pierre (2013). Surveillance of bovine tuberculosis and risk estimation of a future reservoir formation in wildlife in Switzerland and Liechtenstein. PLoS ONE, 8(1):e54253.

Hombach, Michael; Böttger, Erik C; Roos, Malgorzata (2013). The critical influence of the intermediate category on interpretation errors in revised EUCAST and CLSI antimicrobial susceptibility testing guidelines. Clinical Microbiology and Infection, 19(2):E59-71.

Böttger, Erik C; Schacht, Jochen (2013). The mitochondrion: a perpetrator of acquired hearing loss. Hearing research, 303:12-19.

Sirgel, Frederick A; Warren, Robin M; Böttger, Erik C; Klopper, Marisa; Victor, Thomas C; van Helden, Paul D (2013). The rationale for using rifabutin in the treatment of MDR and XDR tuberculosis outbreaks. PLoS ONE, 8(3):e59414.

Böttger, Erik C (2013). Transmission of M abscessus in patients with cystic fibrosis. Lancet, 382(9891):503-504.

Marais, Ben J; Lönnroth, Knut; Lawn, Stephen D; Migliori, Giovanni Battista; Mwaba, Peter; Glaziou, Philippe; Bates, Matthew; Colagiuri, Ruth; Zijenah, Lynn; Swaminathan, Soumya; Memish, Ziad A; Pletschette, Michel; Hoelscher, Michael; Abubakar, Ibrahim; Hasan, Rumina; Zafar, Afia; Pantaleo, Guiseppe; Craig, Gill; Kim, Peter; Maeurer, Markus; Schito, Marco; Zumla, Alimuddin (2013). Tuberculosis comorbidity with communicable and non-communicable diseases: integrating health services and control efforts. The Lancet infectious diseases, 13(5):436-448.

Giuliani, L. Vergleich von Antikörpern gegen Chlamydia trachomatis im Serum mit lokalen Antikörpern gegen C. trachomatis im Zervikalschleim. 2013, University of Zurich, Faculty of Medicine.

Gizard, Yann; Zbinden, Andrea; Schrenzel, Jacques; François, Patrice (2013). Whole-Genome Sequences of Streptococcus tigurinus Type Strain AZ_3a and S. tigurinus 1366, a Strain Causing Prosthetic Joint Infection. Genome Announcements, 1(2):e00210-e00212.

2012

Wöllner, Jens; Schmidig, Kathrin; Gregorini, Flavia; Kessler, Thomas M; Zbinden, Reinhard; Mehnert, Ulrich (2012). Is there a direct antimicrobial effect of botulinum neurotoxin type A? BJU International, 110(11):E886-90.

Maurer, Florian P; Rüegger, Vera; Ritter, Claudia; Bloemberg, Guido V; Böttger, Erik C (2012). Acquisition of clarithromycin resistance mutations in the 23S rRNA gene of Mycobacterium abscessus in the presence of inducible erm(41). Journal of Antimicrobial Chemotherapy, 67(11):2606-2611.

Maurer, Florian. Acquisition of clarithromycin resistance mutations in the 23S rRNA gene of Mycobacterium abscessus in the presence of inducible erm(41). 2012, University of Zurich, Faculty of Medicine.

Jansen, Felix Christian. Analyse der nicht beurteilbaren Resultate des Quantiferon-TB Gold (n-Tube Method) Tests. 2012, University of Zurich, Faculty of Medicine.

Savaria, F; Zbinden, R; Wüst, J; Burnens, A; Ledergerber, B; Weber, R; Kovari, H (2012). Antibiotikaresistenzen von E.coli in Urinproben: Prävalenzdaten dreier Laboratorien im Raum Zürich von 1985 bis 2010. Praxis, 101(9):573-579.

Lucke, Katja; Hombach, Michael; Friedel, Ute; Ritter, Claudia; Böttger, Erik C (2012). Automated quantitative drug susceptibility testing of non-tuberculous mycobacteria using MGIT 960/EpiCenter TB eXiST. Journal of Antimicrobial Chemotherapy, 67(1):154-158.

Petrera, Agnese. Characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and generation of vaccine strains against tuberculosis. 2012, University of Zurich, Faculty of Medicine.

Polsfuss, Silke; Bloemberg, Guido V; Giger, Jacqueline; Meyer, Vera; Hombach, Michael (2012). Comparison of European Committee on Antimicrobial Susceptibility Testing (EUCAST) and CLSI screening parameters for the detection of extended-spectrum β-lactamase production in clinical Enterobacteriaceae isolates. Journal of Antimicrobial Chemotherapy, 67(1):159-166.

Dengler, Vanina; Meier, Patricia Stutzmann; Heusser, Ronald; Kupferschmied, Peter; Fazekas, Judit; Friebe, Sarah; Staufer, Sibylle Burger; Majcherczyk, Paul A; Moreillon, Philippe; Berger-Bächi, Brigitte; McCallum, Nadine (2012). Deletion of hypothetical wall teichoic acid ligases in Staphylococcus aureus activates the cell wall stress response. FEMS Microbiology Letters, 333(2):109-120.

Prianfar, Golzar. Die Wirkung von natürlichen Stoffen – wie Knoblauch und Honig – gegen Bakterien. 2012, University of Zurich, Faculty of Medicine.

Matt, Tanja; Ng, Chyan Leong; Lang, Kathrin; Sha, Su-Hua; Akbergenov, Rashid; Shcherbakov, Dmitri; Meyer, Martin; Duscha, Stefan; Xie, Jing; Dubbaka, Srinivas R; Perez-Fernandez, Déborah; Vasella, Andrea; Ramakrishnan, V; Schacht, Jochen; Böttger, Erik C (2012). Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 109(27):10984-10989.

Fenner, Lukas; Egger, Matthias; Bodmer, Thomas; Altpeter, Ekkehardt; Zwahlen, Marcel; Jaton, Katia; Pfyffer, Gaby E; Borrell, Sonia; Dubuis, Olivier; Bruderer, Thomas; Siegrist, Hans H; Furrer, Hansjakob; Calmy, Alexandra; Fehr, Jan; Stalder, Jesica Mazza; Ninet, Béatrice; Böttger, Erik C; Gagneux, Sebastien (2012). Effect of mutation and genetic background on drug resistance in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy, 56(6):3047-3053.

Hombach, Michael; Bloemberg, Guido V; Böttger, Erik C (2012). Effects of clinical breakpoint changes in CLSI guidelines 2010/2011 and EUCAST guidelines 2011 on antibiotic susceptibility test reporting of Gram-negative bacilli. Journal of Antimicrobial Chemotherapy, 67(3):622-632.

Inauen, Corinne. Epidemiologie der Antibiotikaresistenz von 1985 bis 2009 am Institut für Medizinische Mikrobiologie der Universität Zürich. 2012, University of Zurich, Faculty of Medicine.

Polsfuss, Silke; Bloemberg, Guido V; Giger, Jacqueline; Meyer, Vera; Böttger, Erik C; Hombach, Michael (2012). Evaluation of a diagnostic flow chart for detection and confirmation of extended spectrum β-lactamases (ESBL) in Enterobacteriaceae. Clinical Microbiology and Infection, 18(12):1194-1204.

Zbinden, A; Imhof, A; Wilhelm, M J; Ruschitzka, F; Wild, P; Bloemberg, G V; Mueller, N J (2012). Fatal outcome after heart transplantation caused by Aspergillus lentulus. Transplant Infectious Disease, 14(5):E60-E63.

Tschumi, Andreas; Grau, Thomas; Albrecht, Dirk; Rezwan, Mandana; Antelmann, Haike; Sander, Peter (2012). Functional analyses of mycobacterial lipoprotein diacylglyceryl transferase and comparative secretome analysis of a mycobacterial lgt mutant. Journal of Bacteriology, 194(15):3938-3949.

Petrera, Agnese; Amstutz, Beat; Gioia, Magda; Hähnlein, Janine; Baici, Antonio; Selchow, Petra; Ferraris, Davide M; Rizzi, Menico; Sbardella, Diego; Marini, Stefano; Coletta, Massimo; Sander, Peter (2012). Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates. Biological Chemistry, 393(7):631-640.

Ledermann, Raphael. Identification of filamentous fungi with MALDI-TOF MS proteomic phenotyping. 2012, University of Zurich, Faculty of Medicine.

Rosenberger, Tobias. Identification of novel components of mycobacterial protein translocation systems. 2012, University of Zurich, Faculty of Medicine.

Houghton, Joanna; Townsend, Carolin; Williams, Alan R; Rodgers, Angela; Rand, Lucinda; Walker, K Barry; Böttger, Erik C; Springer, Burkhard; Davis, Elaine O (2012). Important role for Mycobacterium tuberculosis UvrD1 in pathogenesis and persistence apart from its function in nucleotide excision repair. Journal of Bacteriology, 194(11):2916-2923.

Böttger, Erik C (2012). Interferon-γ release assays and the risk of developing active tuberculosis. American Journal of Respiratory and Critical Care Medicine, 185(7):786-787; author reply 787.

Hugelshofer, M; Achermann, Y; Kovari, H; Dent, W; Hombach, M; Bloemberg, G (2012). Meningoencephalitis with Subdural Empyema Caused by Toxigenic Clostridium perfringens Type A. Journal of Clinical Microbiology, 50(10):3409-3411.

Klingenberg, Roland; Schmied, Christian; Falk, Volkmar; Lüscher, Thomas F; Zbinden, Andrea; Corti, Roberto (2012). Molecular evidence of Enterococcus faecalis in an occluding coronary thrombus from a patient with late prosthetic valve endocarditis. Clinical Research in Cardiology, 101(12):1021-1023.

Sirgel, F A; Tait, M; Warren, R M; Streicher, E M; Böttger, E C; Van Helden, P D; Gey Van Pittius, N C; Coetzee, G; Hoosain, E Y; Chabula-Nxiweni, M; Hayes, C; Victor, T C; Trollip, A (2012). Mutations in the rrs A1401G gene and phenotypic resistance to amikacin and capreomycin in mycobacterium tuberculosis. Microbial Drug Resistance, 18(2):193-197.

Streicher, E M; Bergval, I; Dheda, K; Böttger, E C; Gey van Pittius, N C; Bosman, M; Coetzee, G; Anthony, R M; van Helden, P D; Victor, T C; Warren, R M (2012). Mycobacterium tuberculosis population structure determines the outcome of genetics-based second-line drug resistance testing. Antimicrobial Agents and Chemotherapy, 56(5):2420-2427.

Fenner, L; Gagneux, S; Helbling, P; Battegay, M; Rieder, H L; Pfyffer, G E; Zwahlen, M; Furrer, H; Siegrist, H H; Fehr, J; Dolina, M; Calmy, A; Stucki, D; Jaton, K; Janssens, J P; Stalder, J M; Bodmer, T; Ninet, B; Böttger, E C; Egger, M (2012). Mycobacterium tuberculosis transmission in a country with low tuberculosis incidence: Role of immigration and HIV infection. Journal of Clinical Microbiology, 50(2):388-395.

Schulthess, Bettina; Bloes, Dominik A; Berger-Bächi, Brigitte (2012). Opposing roles of σB and σB-controlled SpoVG in the global regulation of esxA in Staphylococcus aureus. BMC Microbiology, 12:17.

Grau, Thomas; Selchow, Petra; Tigges, Marcel; Burri, Reto; Gitzinger, Marc; Böttger, Erik C; Fussenegger, Martin; Sander, Peter (2012). Phenylethyl butyrate enhances the potency of second-line drugs against clinical isolates of Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy, 56(2):1142-1145.

Strickler, Julia. Propionibacterium acnes, Infektionen und Resistenzsituation im Raum Zürich von 1997-2006. 2012, University of Zurich, Faculty of Medicine.

Corti, M A M; Bloemberg, G V; Borelli, S; Kutzner, H; Eich, G; Hoelzle, L; Lautenschlager, S (2012). Rare human skin infection with Corynebacterium ulcerans: transmission by a domestic cat. Infection, 40(5):575-578.

Zbinden, Andrea; Mueller, Nicolas J; Tarr, Philip E; Spröer, Cathrin; Keller, Peter M; Bloemberg, Guido V (2012). Streptococcus tigurinus sp. nov., isolated from blood of patients with endocarditis, meningitis and spondylodiscitis. International Journal of Systematic and Evolutionary Microbiology, 62(Pt 12):2941-2945.

Zbinden, Andrea; Mueller, Nicolas J; Tarr, Philip E; Eich, Gerhard; Schulthess, Bettina; Bahlmann, Anna S; Keller, Peter M; Bloemberg, Guido V (2012). Streptococcus tigurinus, a novel member of the Streptococcus mitis group, causes invasive infections. Journal of Clinical Microbiology, 50(9):2969-2973.

Salian, Sumantha; Matt, Tanja; Akbergenov, Rashid; Harish, Shinde; Meyer, Martin; Duscha, Stefan; Shcherbakov, Dmitri; Bernet, Bruno B; Vasella, Andrea; Westhof, Eric; Böttger, Erik C (2012). Structure-activity relationships among the kanamycin aminoglycosides: role of ring I hydroxy and amino groups. Antimicrobial Agents and Chemotherapy, 56(12):6104-6108.

Bulut, Karl. Tetrazyklin – ein komplexer Ligand: Synthese von Tetrazyklin – Komplexen und Wirkungsnachweise auf E. coli und S. aureus. 2012, University of Zurich, Faculty of Medicine.

Fenner, Lukas; Gagneux, Sebastien; Janssens, Jean-Paul; Fehr, Jan; Cavassini, Matthias; Hoffmann, Matthias; Bernasconi, Enos; Schrenzel, Jacques; Bodmer, Thomas; Böttger, Erik C; Helbling, Peter; Egger, Matthias (2012). Tuberculosis in HIV-negative and HIV-infected patients in a low-incidence country: clinical characteristics and treatment outcomes. PLoS ONE, 7(3):e34186.

Thierfelder, C; Keller, P M; Kocher, C; Gaudenz, R; Hombach, M; Bloemberg, G V; Ruef, C (2012). Vancomycin-resistant Enterococcus. Swiss Medical Weekly, 142(142):0.

Birrer, Deborah. Vorkommen von Bakterien bei Automaten. 2012, University of Zurich, Faculty of Medicine.

Matt, Tanja. With an eye towards more selective drugs: the ribosome as antibiotic drug target. 2012, University of Zurich, Faculty of Medicine.

Sirgel, Frederick A; Warren, Robin M; Streicher, Elizabeth M; Victor, Thomas C; van Helden, Paul D; Böttger, Erik C (2012). embB 306 Mutations as Molecular Indicators to Predict Ethambutol Susceptibility in Mycobacterium tuberculosis. Chemotherapy, 58(5):358-363.

Sirgel, Frederick A; Warren, Robin M; Streicher, Elizabeth M; Victor, Thomas C; van Helden, Paul D; Böttger, Erik C (2012). gyrA mutations and phenotypic susceptibility levels to ofloxacin and moxifloxacin in clinical isolates of Mycobacterium tuberculosis. Journal of Antimicrobial Chemotherapy, 67(5):1088-1093.

2011

Polsfuss, S; Bloemberg, G V; Giger, J; Meyer, V; Böttger, E C; Hombach, M (2011). A practical approach for reliable detection of AmpC Beta-Lactamase producing Enterobacteriaceae. Journal of Clinical Microbiology, 49(8):2798-2803.

Müller, B; Warren, R M; Williams, M; Böttger, E C; Gey Van Pittius, N C; Victor, T C (2011). Acquisition, transmission and amplification of drug-resistant tuberculosis. In: Donald, P R; Van Helden, P D. Antituberculosis Chemotherapy. Basel [etc.]: Karger, 96-104.

Zbinden, R; von Graevenitz, A (2011). Actinobacillus, Capnocytophaga, Eikenella, Kingella, Pasteurella, and other fastidious or rarely encountered gram-negative rods. In: Versalovic, J; Carroll, K C; Jorgensen, J H; Funke, G; Landry, M L; Warnock, D W. Manual of Clinical Microbiology. Washington DC: ASM Press, 574-588.

von Graevenitz, A (2011). Actinomyces neuii: Review of an unusual infectious agent. Infection, 39(2):97-100.

Dengler, M. Analysis of Staphylococcus aureus isolates from the ANTIRESDEV study focussing on antibiotic resistance and fitness. 2011, University of Zurich, Faculty of Medicine.

Rampini, S K; Bloemberg, G V; Keller, P M; Büchler, A C; Dollenmaier, G; Speck, R F; Böttger, E C (2011). Broad-range 16S rRNA gene polymerase chain reaction for diagnosis of culture-negative bacterial infections. Clinical Infectious Diseases, 53(12):1245-1251.

El Bulbeisi, K. Carbapenamases, a threat to control. 2011, University of Zurich, Faculty of Medicine.

Prinz, B. Cloning, expression and characterization of Mycobacterium tuberculosis IpqL and IpqM. 2011, University of Zurich, Faculty of Medicine.

Kupferschmied, P. Construction and visualization of fluorescent reporter fusions to study the cell wall stress stimulon of Staphylococcus aureus. 2011, University of Zurich, Faculty of Medicine.

Quiblier, C; Zinkernagel, A S; Schuepbach, R A; Berger-Bächi, B; Senn, M M (2011). Contribution of SecDF to Staphylococcus aureus resistance and expression of virulence factors. BMC Microbiology, 11:72.

Ferraris, D M; Sbardella, D; Petrera, A; Marini, S; Amstutz, B; Coletta, M; Sander, P; Rizzi, M (2011). Crystal structure of mycobacterium tuberculosis ZMP1, a metalloprotease involved in pathogenicity. Journal of Biological Chemistry, 286(37):32475-32482.

Akbergenov, R; Shcherbakov, D; Matt, T; Duscha, S; Meyer, Martin; Perez Fernandez, D; Pathak, R; Harish, S; Kudyba, I; Dubakka, S R; Silva, S; Ruiz Ruiz, M C; Salian, S; Vasella, A; Böttger, E C (2011). Decoding and deafness: two sides of a coin. In: Rodnina, M V; Wintermeyer, W; Green, R. Ribosomes: Structure, Function and Dynamics. Vienna, Austria: Springer Verlag, 249-261.

Peter-Getzlaff, S; Polsfuss, S; Poledica, M; Hombach, M; Giger, J; Böttger, E C; Zbinden, R; Bloemberg, G V (2011). Detection of AmpC beta-lactamase in Escherichia coli: comparison of three phenotypic confirmation assays and genetic analysis. Journal of Clinical Microbiology, 49(8):2924-2932.

Widdick, D A; Hicks, M G; Thompson, B J; Tschumi, A; Chandra, G; Sutcliffe, I C; Brülle, J K; Sander, P; Palmer, T; Hutchings, M I (2011). Dissecting the complete lipoprotein biogenesis pathway in Streptomyces scabies. Molecular Microbiology, 80(5):1395-1412.

Böttger, E C (2011). Drug resistance in mycobacterium tuberculosis: molecular mechanisms and laboratory susceptibility testing. In: Donald, P R; Van Helden, P D. Antituberculosis Chemotherapy. Basel [etc.]: Karger, 128-144.

Meier, S; Weber, R; Zbinden, R; Ruef, C; Hasse, B (2011). Extended-spectrum β-lactamase-producing gram-negative pathogens in community-acquired urinary tract infections: an increasing challenge for antimicrobial therapy. Infection, 39(4):333-340.

Geser, N; Stephan, Roger; Kuhnert, P; Zbinden, R; Kaeppeli, U; Cernela, N; Haechler, H (2011). Fecal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae in swine and cattle at slaughter in Switzerland. Journal of Food Protection, 74(3):446-449.

Hobbie, S N; Kaiser, M; Schmidt, S; Shcherbakov, D; Janusic, T; Brun, R; Böttger, E C (2011). Genetic reconstruction of protozoan rRNA decoding sites provides a rationale for paromomycin activity against Leishmania and Trypanosoma. PLoS Neglected Tropical Diseases, 5(5):e1161.

Zbinden, A; Zbinden, R; Natalucci, G; Zimmermann, R; Bucher, H U; Krafft, A (2011). How useful is routine amniotic fluid and neonatal surface swab microbiology at Caesarean section? Zeitschrift für Geburtshilfe und Neonatologie, 215(5):205-208.

Preiswerk, B; Ullrich, S; Speich, R; Bloemberg, G V; Hombach, M (2011). Human infection with Delftia tsuruhatensis isolated from a central venous catheter. Journal of Medical Microbiology, 60(2):246-248.

Dengler, V; Meier Stutzmann, P; Heusser, R; Berger-Bächi, B; McCallum, N (2011). Induction kinetics of the Staphylococcus aureus cell wall stress stimulon in response to different cell wall active antibiotics. BMC Microbiology, 11:16.

Giner, A M; Kuster, S P; Zbinden, R; Ruef, C; Ledergerber, B; Weber, R (2011). Initial management of and outcome in patients with pneumococcal bacteremia: a retrospective study at a Swiss university hospital, 2003-2009. Infection, 39(6):519-526.

Schiefer, H G; von Graevenitz, A (2011). Klinitseskaja Mikrobiologija. In: Schill, W B; Comhaire, F H; Hargreave, T B. Andrology for the Clinician (Russian Version). Moskwa, RU: Geotar Media, 507-516.

Grau, Thomas. Lipoprotein localization signals and evaluation of novel drug targets to combat tuberculosis. 2011, University of Zurich, Faculty of Science.

Over, B; Heusser, R; McCallum, N; Schulthess, B; Kupferschmied, P; Gaiani, J M; Sifri, C D; Berger-Bächi, B; Stutzmann Meier, P (2011). LytR-CpsA-Psr proteins in Staphylococcus aureus display partial functional redundancy and the deletion of all three severely impairs septum placement and cell separation. FEMS Microbiology Letters, 320(2):142-51.

Akbergenov, R; Shcherbakov, D; Matt, T; Duscha, S; Meyer, Martin; Wilson, D N; Böttger, E C (2011). Molecular basis for the selectivity of antituberculosis compounds capreomycin and viomycin. Antimicrobial Agents and Chemotherapy, 55(10):4712-4717.

McCallum, N; Stutzmann Meier, P; Heusser, R; Berger-Bächi, B (2011). Mutational analyses of ORFs within the vraSR operon and their roles in the cell wall stress response of Staphylococcus aureus. Antimicrobial Agents and Chemotherapy, 55(4):1391-1402.

Sahraoui, N; Ballif, M; Zelleg, S; Yousfi, N; Ritter, C; Friedel, U; Amstutz, B; Yala, D; Boulahbal, F; Guetarni, D; Zinsstag, J; Keller, P M (2011). Mycobacterium algericum sp. nov., a novel rapidly growing species related to M. terrae complex and associated with goat lung lesions. International Journal of Systematic and Evolutionary Microbiology, 61(8):1870-1874.

Tortoli, E; Böttger, E C; Fabio, A; Falsen, E; Gitti, Z; Grottola, A; Klenk, H P; Mannino, R; Mariottini, A; Messinò, M; Pecorari, M; Rumpianesi, F (2011). Mycobacterium europaeum sp. nov., a scotochromogenic species related to Mycobacterium simiae complex. International Journal of Systematic and Evolutionary Microbiology, 61(7):1606-1611.

Akshay, S; Bertea, M; Hobbie, S N; Oettinghaus, B; Shcherbakov, D; Böttger, E C; Akbergenov, R (2011). Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis. Antimicrobial Agents and Chemotherapy, 55(9):4096-4102.

Zbinden, A C; Keller, P M; Bloemberg, G V (2011). Rapid molecular detection of tuberculosis. New England Journal of Medicine, 364(2):183.

Johansen, P; Fettelschoss, A; Amstutz, B; Selchow, P; Waeckerle-Men, Y; Keller, P; Deretic, V; Held, L; Kündig, T M; Böttger, E C; Sander, P (2011). Relief from zmp1-mediated arrest of phagosome maturation is associated with facilitated presentation and enhanced immunogenicity of mycobacterial antigens. Clinical and Vaccine Immunology : CVI, 18(6):907-913.

Schulthess, B. Role of the sigB-dependent yabJ-spoVG operon in the regulation of antibiotic resistance and virulence determinants in Staphylococcus aureus. 2011, University of Zurich, Faculty of Medicine.

Rossi, F; Khanduja, J S; Bortoluzzi, A; Houghton, J; Sander, P; Güthlein, C; Davis, E O; Springer, B; Böttger, E C; Relini, A; Penco, A; Muniyappa, K; Rizzi, M (2011). The biological and structural characterization of Mycobacterium tuberculosis UvrA provides novel insights into its mechanism of action. Nucleic Acids Research, 39(16):7316-7328.

Böttger, E C (2011). The ins and outs of mycobacterium tuberculosis drug susceptibility testing: Themed review 'Therapeutic efficiency in the presence of resistance mechanisms: (when) to give-or not to give?'. Clinical Microbiology and Infection, 17(8):1128-1134.

Schulthess, B; Bloes, D A; François, P; Girardi, M; Schrenzel, J; Bischoff, M; Berger-Bächi, B (2011). The {sigma}B-dependent yabJ-spoVG operon is involved in the regulation of extracellular nuclease, lipase, and protease expression in staphylococcus aureus. Journal of Bacteriology, 193(18):4954-4962.

Williams, A; Güthlein, C; Beresford, N; Böttger, E C; Springer, B; Davis, E O (2011). UvrD2 is essential in mycobacterium tuberculosis, but its helicase activity is not required. Journal of Bacteriology, 193(17):4487-4494.

van Ingen, J; de Lange, W C; Boeree, M J; Iseman, M D; Daley, C L; Heifets, L B; Böttger, E C; van Soolingen, D (2011). XDR tuberculosis. Lancet Infectious Diseases, 11(8):585.

Zbinden, A; Köhler, N; Bloemberg, G V (2011). recA-based PCR assay for accurate differentiation of streptococcus pneumoniae from other viridans streptococci. Journal of Clinical Microbiology, 49(2):523-527.

Casas, M. Überprüfung der Auswirkung DNA-schädigender Substanzen auf die Mutationsrate und Resistenzbildung von E. coli Bakterien. 2011, University of Zurich, Faculty of Medicine.

2010

Flammer Anikpeh, Y; Keller, P; Bloemberg, G V; Grünenfelder, J; Zinkernagel, A (2010). Spacecraft bacterium, Paenibacillus pasadenensis, causing wound infection in humans. BMJ Case Reports:bcr.06.2010.3058.

Nicoletti, J; Kuster, Stefan P; Sulser, T; Zbinden, R; Ruef, C; Ledergerber, B; Weber, R (2010). Risk factors for urinary tract infections due to ciprofloxacin-resistant Escherichia coli in a tertiary care urology department in Switzerland. Swiss Medical Weekly, (140):w13059.

McCallum, N; Berger-Bächi, B; Senn, M M (2010). Regulation of antibiotic resistance in Staphylococcus aureus. International Journal of Medical Microbiology, 300(2-3):118-129.

Imkamp, F; Rosenberger, T; Striebel, F; Keller, P M; Amstutz, B; Sander, P; Weber-Ban, E (2010). Deletion of dop in Mycobacterium smegmatis abolishes pupylation of protein substrates in vivo. Molecular Microbiology, 75(3):744-754.

Brülle, J K; Grau, T; Tschumi, A; Auchli, Y; Burri, R; Polsfuss, S; Keller, P M; Hunziker, P; Sander, P (2010). Cloning, expression and characterization of Mycobacterium tuberculosis lipoprotein LprF. Biochemical and Biophysical Research Communications (BBRC), 391(1):679-684.

Lucke, K; Kuster, S P; Bertea, M; Ruef, C; Bloemberg, G V (2010). A deep sternal wound infection caused by Ureaplasma urealyticum. Journal of Medical Microbiology, 59(Pt 10):1254-1256.

Joller, N; Weber, S S; Müller, A J; Spörri, R; Selchow, P; Sander, P; Hilbi, H; Oxenius, A (2010). Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 107(47):20441-20446.

Peter-Getzlaff, S; Lüthy, J; Voit, A; Bloemberg, G V; Böttger, E C (2010). Detection and identification of Mycobacterium spp. in clinical specimens by combining the Roche Cobas Amplicor Mycobacterium tuberculosis assay with Mycobacterium genus detection and nucleic acid sequencing. Journal of Clinical Microbiology, 48(11):3943-3948.

Keller, P M; Rampini, S K; Bloemberg, G V (2010). Detection of a mixed infection in a culture-negative brain abscess by broad-spectrum bacterial 16S rRNA gene PCR. Journal of Clinical Microbiology, 48(6):2250-2252.

Shcherbakov, D; Akbergenov, R; Mattina, T; Sander, P; Andersson, D I; Böttger, E C (2010). Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis. Molecular Microbiology, 77(4):830-840.

Imkamp, F; Striebel, F; Sutter, M; Ozcelik, D; Zimmermann, N; Sander, P; Weber-Ban, E (2010). Dop functions as a depupylase in the prokaryotic ubiquitin-like modification pathway. EMBO Reports, 11(10):791-797.

Zbinden, A C. Entwicklung einer auf dem recA-Gen basierenden molekularen Identifizierung von Streptococcus spp., Enterobacteriaceae spp. und Pseudomonas spp. 2010, University of Zurich, Faculty of Medicine.

Ciardo, D E; Burger, S; Payer, M; Lee, C; McCallum, N (2010). GeneXpert captures unstable methicillin-resistant Staphylococcus aureus prone to rapidly losing the mecA gene. Journal of Clinical Microbiology, 48(8):3030-3032.

Kayser, F H; Böttger, E C; Zinkernagel, R M; Haller, O; Eckert, J; Deplazes, P (2010). Medizinische Mikrobiologie: Taschenlehrbuch. Stuttgart: Thieme.

Böttger, E C (2010). Mutant A1555G mitochondrial 12S rRNA and aminoglycoside susceptibility. Antimicrobial Agents and Chemotherapy, 54(7):3073-3074; author reply 3074.

Kalapala, S K; Hobbie, S N; Böttger, E C; Shcherbakov, D (2010). Mutation K42R in ribosomal protein S12 does not affect susceptibility of Mycobacterium smegmatis 16S rRNA A-site mutants to 2-deoxystreptamines. PLoS ONE, 5(9):e11960.

Long, K S; Munck, C; Andersen, T B M; Schaub, M A; Hobbie, S N; Böttger, E C; Vester, B (2010). Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. Antimicrobial Agents and Chemotherapy, 54(11):4705-4713.

Tschumi, A. Mycobacterial lipoproteins are triacylated and Mycobacterium tuberculosis Ppm1 prevents phagosome maturation. 2010, University of Zurich, Faculty of Science.

Koligi, K; Mertz, D; Benz, D; Vogt, T; Bloemberg, G V; Winter, L; Tyndall, A; Battegay, M; Walker, U A (2010). Oligoarthritis durch Tropheryma whipplei „Of bugs and joints“. Der Internist, 52(7):884-888.

von Graevenitz, A; Amann, R (2010). Recent advances in microbial taxonomy. Jahrbuch Leopoldina. Reihe 3, 55/2009:395-400.

Keller, P M; Rampini, S K; Büchler, A C; Eich, G; Wanner, R M; Speck, R F; Böttger, E C; Bloemberg, G V (2010). Recognition of potentially novel human disease-associated pathogens by implementation of systematic 16S rRNA gene sequencing in the diagnostic laboratory. Journal of Clinical Microbiology, 48(9):3397-3402.

Messner, Simon. Regulation of poly(ADP-ribose) polymerase 1 by sumoylation and investigation of histone poly(ADP-ribosyl)ation. 2010, University of Zurich, Faculty of Science.

Kuster, S P; Hasse, B; Huebner, V; Bansal, V; Zbinden, R; Ruef, C; Ledergerber, B; Weber, R (2010). Risks factors for infections with extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae at a tertiary care university hospital in Switzerland. Infection, 38(1):33-40.

Fehr, J S; Bloemberg, G V; Ritter, C; Hombach, M; Lüscher, T F; Weber, R; Keller, P M (2010). Septicemia caused by tick-borne bacterial pathogen Candidatus Neoehrlichia mikurensis. Emerging Infectious Diseases, 16(7):1127-1129.

Subramanian, Akshay. Sequence variations in the ribosomal decoding and peptidyl transferase sites determine sensitivity to aminoglycosides and macrolides. 2010, University of Zurich, Faculty of Science.

Kalapala, Sarath Kumar. Study of aminoglycoside antibiotics interaction with eukaryotic ribosomal decoding sites using bacterial hybrid ribosomes. 2010, University of Zurich, Faculty of Science.

Ciardo, D E; Lucke, K; Imhof, A; Bloemberg, G V; Böttger, E C (2010). Systematic internal transcribed spacer sequence analysis for identification of clinical mold isolates in diagnostic mycology: a 5-year study. Journal of Clinical Microbiology, 48(8):2809-2813.

Matt, T; Akbergenov, R; Shcherbakov, D; Böttger, E C (2010). The ribosomal A-site: decoding, drug target and disease. Israel Journal of Chemistry, 50(1):60-70.

Bottova, Iveta. The role of P-glycoprotein in host-pathogen interactions. 2010, University of Zurich, Faculty of Science.

McCallum, N; Hinds, J; Ender, M; Berger-Bächi, B; Stutzmann Meier, P (2010). Transcriptional profiling of XdrA, a new regulator of spa transcription in Staphylococcus aureus. Journal of Bacteriology, 192(19):5151-5164.

2009

Tschumi, A; Nai, C; Auchli, Y; Hunziker, P; Gehrig, P; Keller, P; Grau, T; Sander, P (2009). Identification of apolipoprotein n-acyltransferase (LNT) in mycobacteria. Journal of Biological Chemistry, 284(40):27146-27156.

Berger-Bächi, B; Senn, M M; Ender, M; Seidl, K; Hübscher, J; Schulthess, B; Heusser, R; Stutzmann-Meier, P; McCallum, N (2009). Resistance to β-Lactam Antibiotics. In: Corssley, K B; Jefferson, K K; Archer, G; Fowler, V G. Staphylococci in human diseases (2nd edition). UK: Blackwell, 170-192.

Böttger, E C; Springer, B (2009). Mycobacterium tuberculosis: drug resistance and genetic mechanisms - facts, artifacts and fallacies. In: Kaufmann, S H E; Walker, B. AIDS and tuberculosis: a deadly liaison. Weinheim: Wiley-VCH, 103-121.

Gargis, S R; Gargis, A S; Heath, H E; Heath, L S; LeBlanc, P A; Senn, M M; Berger-Bächi, B; Simmonds, R S; Sloan, G L (2009). Zif, the zoocin A immunity factor, is a FemABX-like immunity protein with a novel mode of action. Applied and Environmental Microbiology, 75(19):6205-6210.

Guggenheim, M; Zbinden, R; Handschin, A E; Gohritz, A; Altintas, M A; Giovanoli, P (2009). Changes in bacterial isolates from burn wounds and their antibiograms: a 20-year study (1986-2005). Burns, 35(4):553-560.

Ender, M; Burger, S; Sokoli, A; Zbinden, R; Berger-Bächi, B; Heusser, R; Senn, M M; McCallum, N (2009). Variability of SCCmec in the Zurich area. European Journal of Clinical Microbiology and Infectious Diseases, 28(6):647-653.

Seidl, K; Müller, S; François, P; Kriebitzsch, C; Schrenzel, J; Engelmann, S; Bischoff, M; Berger-Bächi, B (2009). Effect of a glucose impulse on the CcpA regulon in Staphylococcus aureus. BMC Microbiology, 9:95.

Long, K S; Poehlsgaard, J; Hansen, L H; Hobbie, S N; Böttger, E C; Vester, B (2009). Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket. Molecular Microbiology, 71(5):1218-1227.

Güthlein, C; Wanner, R M; Sander, P; Davis, E O; Bosshard, M; Jiricny, J; Böttger, E C; Springer, B (2009). Characterisation of the mycobacterial NER system reveals novel functions of uvrD1 helicase. Journal of Bacteriology, 191(2):555-562.

Ender, M; Berger-Bächi, B; McCallum, N (2009). A novel DNA-binding protein modulating methicillin resistance in staphylococcus aureus. BMC Microbiology, 9:15.

Reichenbach, J; Lopatin, U; Mahlaoui, N; Beovic, B; Siler, U; Zbinden, R; Seger, R A; Galmiche, L; Brousse, N; Kayal, S; Güngör, Tayfun; Blanche, S; Holland, S M (2009). Actinomyces in chronic granulomatous disease: an emerging and unanticipated pathogen. Clinical Infectious Diseases, 49(11):1703-1710.

Meier, S. Characterisation of the SoVG homolog in Staphylococcus aureus. 2009, University of Zurich, Faculty of Science.

Brülle, J. Cloning, expression, localization and characterization of Mycobacterium tuberculosis lipoproteins LprF and LprJ. 2009, Albert-Ludwigs-Universität Freiburg, Mathematisch-Naturwissenschaftliche Fakultät.

Hähnlein, J. Expression and characterization of the putative zinc metalloprotease Zmp1 of Mycobacterium tuberculosis. 2009, University of Zurich, Faculty of Science.

Schulthess, B; Meier, S; Homerova, D; Goerke, C; Wolz, C; Kormanec, J; Berger-Bächi, B; Bischoff, M (2009). Functional characterization of the sigmaB-dependent yabJ-spoVG operon in Staphylococcus aureus: role in methicillin and glycopeptide resistance. Antimicrobial Agents and Chemotherapy, 53(5):1832-1839.

Walch, M; Rampini, S K; Stoeckli, I; Latinovic-Golic, S; Dumrese, C; Sundstrom, H; Vogetseder, A; Marino, J; Glauser, D L; van den Broek, Maries; Sander, P; Groscurth, P; Ziegler, U (2009). Involvement of CD252 (CD134L) and IL-2 in the expression of cytotoxic proteins in bacterial- or viral-activated human T cells. Journal of Immunology, 182(12):7569-7579.

Schiefer, H G; von Graevenitz, A (2009). Microbiologia clinica. In: Schill, W B; Comhaire, F H; Hargreave, T B. Andrologia clinica. Springer Italia, 401-407.

Kayser, F H; Böttger, E C; Zinkernagel, R M; Haller, O; Eckert, J; Deplazes, P (2009). Microbiologie Médicale (Übersetzung der 11. Auflage). Paris: Flammarion.

Zbinden, R (2009). Microbiology. In: Baltensperger, M M; Eyrich, G K. Osteomyelitis of the Jaws. Berlin Heidelberg: Springer Verlag, 135-144.

Hübscher, J; McCallum, N; Sifri, C D; Majcherczyk, P A; Entenza, J M; Heusser, R; Berger-Bächi, B; Stutzmann Meier, P (2009). MsrR contributes to cell surface characteristics and virulence in Staphylococcus aureus. FEMS Microbiology Letters, 295(2):251-260.

Guo, Y L; Mayer, H; Vollmer, W; Dittrich, D; Sander, P; Schultz, A; Schultz, J E (2009). Polyphosphates from Mycobacterium bovis- potent inhibitors of class III adenylate cyclases. FEBS Journal, 276(4):1094-1103.

Springer, B; Lucke, K; Calligaris-Maibach, R; Ritter, C; Böttger, E C (2009). Quantitative drug susceptibility testing of Mycobacterium tuberculosis by use of MGIT 960 and EpiCenter instrumentation. Journal of Clinical Microbiology, 47(6):1773-1780.

Collin, M P; Hobbie, S N; Böttger, E C; Vasella, A (2009). Synthesis and Evaluation of S- and C(1)-Substituted Analogues of Lincomycin. Helvetica Chimica Acta, 92(2):230-266.

Wanner, R M; Castor, D; Güthlein, C; Böttger, E C; Springer, B; Jiricny, J (2009). The uracil DNA glycosylase UdgB of Mycobacterium smegmatis protects the organism from the mutagenic effects of cytosine and adenine deamination. Journal of Bacteriology, 191(20):6312-6319.

2008

Hobbie, S N; Akshay, Subramanian; Kalapala, S K; Bruell, C M; Shcherbakov, D; Böttger, E C (2008). Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 105(52):20888-20893.

Hübscher, J; Lüthy, L; Berger-Bächi, B; Stutzmann Meier, P (2008). Phylogenetic distribution and membrane topology of the LytR-CpsA-Psr protein family. BMC Genomics, 9:617.

Kuster, S P; Ruef, C; Zbinden, R; Gottschalk, J; Ledergerber, B; Neuber, L; Weber, R (2008). Stratification of cumulative antibiograms in hospitals for hospital unit, specimen type, isolate sequence and duration of hospital stay. Journal of Antimicrobial Chemotherapy, 62(6):1451-1461.

Springer, B; Calligaris-Maibach, R C; Ritter, C; Böttger, E C (2008). TB drug resistance in a low endemic area 2004 to 2006: semi-quantitative drug susceptibility testing and genotyping. Journal of Clinical Microbiology, 46(12):4064-4067.

Peter-Getzlaff, S; Lüthy, J; Böddinghaus, B; Böttger, E C; Springer, B (2008). Development and evaluation of a molecular assay for detection of nontuberculous mycobacteria on the basis of the COBAS Amplicor platform. Journal of Clinical Microbiology, 46(12):4023-4028.

Karauzum, H; Ferry, T; de Bentzmann, S; Lina, G; Bes, M; Vandenesch, F; Schmaler, M; Berger-Bächi, B; Etienne, J; Landmann, R (2008). Comparison of adhesion and virulence of two predominant hospital-acquired methicillin-resistant Staphylococcus aureus clones and clonal methicillin-susceptible S. aureus isolates. Infection and Immunity, 76(11):5133-5138.

Pathak, Rashmi; Perez-Fernandez, Déborah; Nandurdikar, Rahul; Kalapala, Sarath K; Böttger, Erik C; Vasella, Andrea (2008). Synthesis and evaluation of paromomycin derivates modified at C(4'). Helvetica Chimica Acta, 91(8):1533-1552.

Seidl, K; Bischoff, M; Berger-Bächi, B (2008). CcpA mediates the catabolite repression of tst in Staphylococcus aureus. Infection and Immunity, 76(11):5093-5099.

von Graevenitz, A (2008). Richard Pfeiffer 1858–1945. Infection, 36(4):392-393.

Zinkernagel, A S; Zinkernagel, M S; Elzi, M V; Genoni, M; Gubler, J; Zbinden, R; Mueller, N J (2008). Significance of Staphylococcus lugdunensis bacteremia: report of 28 cases and review of the literature. Infection, 36(4):314-321.

Weber, Wilfried; Schoenmakers, R; Keller, B; Gitzinger, M; Grau, T; Daoud-El Baba, M; Sander, P; Fussenegger, M (2008). A synthetic mammalian gene circuit reveals antituberculosis compounds. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 105(29):9994-9998.

Ender, M D; McCallum, N; Berger-Bächi, B (2008). Impact of mecA promoter mutations on mecA expression and beta-lactam resistance levels. International Journal of Medical Microbiology, 298(7-8):607-617.

Wanner, R M; Güthlein, C; Springer, B; Böttger, E C; Ackermann, M (2008). Stabilization of the genome of the mismatch repair deficient Mycobacterium tuberculosis by context-dependent codon choice. BMC Genomics, 9:249.

Master, S S; Rampini, S K; Davis, A S; Keller, C; Ehlers, S; Springer, B; Timmins, G S; Sander, P; Deretic, V (2008). Mycobacterium tuberculosis prevents inflammasome activation. Cell Host & Microbe, 3(4):224-232.

Böttger, E C; Springer, B (2008). Tuberculosis: drug resistance, fitness, and strategies for global control. European Journal of Pediatrics, 167(2):141-148.

Güthlein, C; Wanner, R M; Sander, P; Böttger, E C; Springer, B (2008). A mycobacterial smc null mutant is proficient in DNA repair and long-term survival. Journal of Bacteriology, 190(1):452-456.

Bruell, C M; Eichholz, C; Kubarenko, A; Post, V; Katunin, V I; Hobbie, S N; Rodnina, M V; Böttger, E C (2008). Conservation of bacterial protein synthesis machinery: initiation and elongation in Mycobacterium smegmatis. Biochemistry, 47(34):8828-8839.

Amiali, N M; Mulvey, M R; Berger-Bächi, B; Sedman, J; Simor, A E; Ismail, A A (2008). Evaluation of Fourier transform infrared spectroscopy for the rapid identification of glycopeptide-intermediate Staphylococcus aureus. Journal of Antimicrobial Chemotherapy, 61(1):95-102.

Dora, C; Altwegg, M; Gerber, C; Böttger, E C; Zbinden, R (2008). Evaluation of conventional microbiological procedures and molecular genetic techniques for diagnosis of infections in patients with implanted orthopedic devices. Journal of Clinical Microbiology, 46(2):824-825.

Keller, Peter Michael. Generation of unmarked Mycobacterium bovis BCG recA deletion mutants. 2008, University of Zurich, Faculty of Medicine.

Li, W; Fenollar, F; Rolain, J M; Fournier, P E; Feurle, G E; Müller, C; Moos, V; Marth, T; Altwegg, M; Calligaris-Maibach, R C; Schneider, T; Biagi, F; La Scola, B; Raoult, D (2008). Genotyping reveals a wide heterogeneity of Tropheryma whipplei. Microbiology, 154(Pt 2):521-527.

Wölfelschneider, S. Gentechnische Humanisierung von Antibiotikabindestellen im bakteriellen Ribosom. 2008, University of Zurich / University of Heidelberg, Faculty of Medicine.

Seidl, K. Impact of the catabolite control protein CcpA in "Staphylococcus aureus". 2008, University of Zurich, Faculty of Science.

Corrado, N. Insight into the activity of mycobacterial Lnt homologues. 2008, University of Zurich / ETH Zürich, Faculty of Medicine.

Güthlein, Carolin. Investigation of DNA repair pathways and the impact of SMC protein on chromosome stability in mycobacteria. 2008, University of Zurich, Faculty of Science.

Hübscher, J. Investigations on factors modulating methicillin resistance in staphylococcus aureus. 2008, University of Zurich, Faculty of Science.

Rampini, S K; Selchow, P; Keller, C; Ehlers, S; Böttger, E C; Sander, P (2008). LspA inactivation in Mycobacterium tuberculosis results in attenuation without affecting phagosome maturation arrest. Microbiology, 154(Pt 10):2991-3001.

Bruell, C. Mechanismus of protein synthesis in M. smegmatis. 2008, University of Zurich, Faculty of Medicine.

von Graevenitz, A (2008). Microbiologie clinique. In: Schill, W B; Comhaire, F H; Hargreave, T B. Traité d'andrologie à l'usage des cliniciens. Paris: Springer, 401-407.

Hobbie, S N; Bruell, C M; Akshay, S; Kalapala, S K; Shcherbakov, D; Böttger, E C (2008). Mitochondrial deafness alleles confer misreading of the genetic code. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 105(9):3244-3249.

Ender, M. Molecular and functional charactersiation of the Swiss drug clone, a Methicillin-resistenter Staphylococcus aureus. 2008, University of Zurich, Faculty of Science.

Fischer, A H; van der Loo, B; Shär, G M; Zbinden, R; Duru, F; Brunckhorst, C; Rousson, V; Delacrétazy, E; Stuber, T; Oechslin, E N; Follath, F; Jenni, R (2008). Serological evidence for the association of Bartonella henselae infection with arrhythmogenic right ventricular cardiomyopathy. Clinical Cardiology, 31(10):469-471.

Seidl, K; Goerke, C; Wolz, C; Mack, D; Berger-Bächi, B; Bischoff, M (2008). Staphylococcus aureus CcpA affects biofilm formation. Infection and Immunity, 76(5):2044-2050.

Collin, M P; Hobbie, S N; Böttger, E C; Vasella, A (2008). Synthesis of 1,2,3-triazole analogues of lincomycin. Helvetica Chimica Acta, 91(10):1838-1848.

Keller, P M; Böttger, E C; Sander, P (2008).