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Kastrinou-Lampou, Vlasia; Rodríguez-Pérez, Raquel; Poller, Birk; Huth, Felix; Schadt, Heiko S; Kullak-Ublick, Gerd A; Arand, Michael; Camenisch, Gian (2025). Drug-induced cholestasis (DIC) predictions based on in vitro inhibition of major bile acid clearance mechanisms. Archives of Toxicology, 99(1):377-391.
Gagliano, Vanessa; Salemme, Gloria; Ceschi, Alessandro; Greco, Angela; Grignoli, Nicola; Clivio, Luca; Merler, Alessandro; Feyling Benitez, Vanessa; Gianini, Jvan; Zandonà, Martina; Gabutti, Luca (2024). Antipsychotic, benzodiazepine and Z-drug prescriptions in a Swiss hospital network in the Choosing Wisely and COVID-19 eras: a longitudinal study. Swiss Medical Weekly, 154(11):3409.
Noseda, Roberta; Bedussi, Francesca; Giunchi, Valentina; Fusaroli, Michele; Raschi, Emanuel; Ceschi, Alessandro (2024). Reporting of late-onset immune-related adverse events with immune checkpoint inhibitors in VigiBase. Journal for ImmunoTherapy of Cancer, 12(11):e009902.
Noseda, Roberta; Bedussi, Francesca; Panchaud, Alice; Ceschi, Alessandro (2024). Safety of Monoclonal Antibodies Inhibiting PCSK9 in Pregnancy: Disproportionality Analysis in VigiBase®. Clinical Pharmacology and Therapeutics, 116(2):346-350.
Kastrinou-Lampou, Vlasia; Rodríguez-Pérez, Raquel; Poller, Birk; Huth, Felix; Gáborik, Zsuzsanna; Mártonné-Tóth, Beáta; Temesszentandrási-Ambrus, Csilla; Schadt, Heiko S; Kullak-Ublick, Gerd A; Arand, Michael; Camenisch, Gian (2024). Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC). Archives of Toxicology, 98(10):3409-3424.
Samodelov, Sophia L; Gai, Zhibo; De Luca, Francesca; Haldimann, Klara; Hobbie, Sven N; Müller, Daniel; Kullak-Ublick, Gerd A; Visentin, Michele (2024). L-carnitine co-administration prevents colistin-induced mitochondrial permeability transition and reduces the risk of acute kidney injury in mice. Scientific Reports, 14(1):16444.
Trojan, Andreas; Roth, Sven; Atassi, Ziad; Kiessling, Michael; Zenhaeusern, Reinhard; Kadvany, Yannick; Schumacher, Johannes; Kullak-Ublick, Gerd A; Aapro, Matti; Eniu, Alexandru (2024). Comparison of the Real-World Reporting of Symptoms and Well-Being for the HER2-Directed Trastuzumab Biosimilar Ogivri With Registry Data for Herceptin in the Treatment of Breast Cancer: Prospective Observational Study (OGIPRO) of Electronic Patient-Reported Outcomes. JMIR Cancer, 10:e54178.
Hage, René; Bonzon, Jerome; Schuurmans, Macé M (2024). Direct Oral Anticoagulation in Lung Transplant Recipients. Experimental and Clinical Transplantation, 22(4):249-257.
Duwor, Seth; Brites, Daniela; Mäser, Pascal (2024). Phylogenetic Analysis of Pyruvate-Ferredoxin Oxidoreductase, a Redox Enzyme Involved in the Pharmacological Activation of Nitro-Based Prodrugs in Bacteria and Protozoa. Biology, 13(3):178.
van Rosmalen, Belle V; Visentin, Michele; Furumaya, Alicia; van Delden, Otto M; Kazemier, Geert; van Gulik, Thomas M; Verheij, Joanne; Stieger, Bruno (2024). Association between gadoxetic acid-enhanced MR imaging, organic anion transporters, and farnesoid X receptor in benign focal liver lesions. Drug Metabolism and Disposition, 52(2):118-125.
Xiu, Fangrui; Console, Lara; Indiveri, Cesare; Su, Shanshan; Wang, Tong; Visentin, Michele (2024). Effect of 7-ketocholesterol incorporation on substrate binding affinity and turnover rate of the organic cation transporter 2 (OCT2). Biochemical Pharmacology, 220:116017.
Giovannoni, Luis; Kullak-Ublick, Gerd A; Jetter, Alexander (2024). Developing a Model for Quantifying QTc-Prolongation Risk to Enhance Medication Safety Assessment: A Retrospective Analysis. Journal of Personalized Medicine, 14(2):172.
Duwor, Seth; Enthofer, Katharina; Ganter, Christoph; Poudel, Prabin; Svarin, Anna; Kullak-Ublick, Gerd A (2024). Rescue Therapy for Supratherapeutic Concentrations of Calcineurin Inhibitors Using Potent Cytochrome P450 Inducers. Pharmacoepidemiology, 3(1):33-50.
Noseda, Roberta; Bedussi, Francesca; Gobbi, Claudio; Ceschi, Alessandro; Zecca, Chiara (2024). Calcitonin gene-related peptide antagonists in pregnancy: a disproportionality analysis in VigiBase®. Journal of Headache and Pain, 25(1):10.
Thomson, Paul; Fragkas, Nik; Kafu, Laila M; Aithal, Guruprasad P; Lucena, M Isabel; Terracciano, Luigi; Meng, Xiaoli; Pirmohamed, Munir; Brees, Dominique; Kullak‐Ublick, Gerd A; Odermatt, Alex; Hammond, Thomas; Kammüller, Michael; Naisbitt, Dean J (2024). Patients with naproxen-induced liver injury display T-cell memory responses toward an oxidative (S)-O-Desmethyl Naproxen metabolite but not the acyl glucuronide. Allergy, 79(1):200-214.
Lucena, M I; Villanueva-Paz, M; Alvarez-Alvarez, I; Aithal, G P; Björnsson, E S; Cakan-Akdogan, G; Cubero, F J; Esteves, F; Falcon-Perez, J M; Fromenty, B; Garcia-Ruiz, C; Grove, J I; Konu, O; Kranendonk, M; Kullak-Ublick, G A; Miranda, J P; Remesal-Doblado, A; Sancho-Bru, P; Nelson, L; Andrade, R J; Daly, A K; Fernandez-Checa, J C (2023). Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet. Pharmacological Research, 200:107046.
Hitz, Paolo; Pagnamenta, Alberto; Pertusini, Laura; Terrot, Tatiana; Franzosi, Yves; Bassi, Jessica; Silacci-Fregni, Chiara; Gaia, Valeria; Martinetti, Gladys; Keller, Franco; Berwert, Lorenzo; Ogna, Valentina Forni; Lavorato-Hadjeres, Soraya; Giunzioni, Davide; D’Ermo, Andrea; Valnegri, Alan; Ferrari, Paolo; Corti, Davide; Ceschi, Alessandro; Cippà, Pietro; Piccoli, Luca; Giannini, Olivier (2023). Prevalence of SARS-CoV-2 infection and impact of vaccination in dialysis patients over two years of the pandemic. Journal of Nephrology, 36(9):2665-2667.
Addetia, Amin; Piccoli, Luca; Case, James Brett; Park, Young-Jun; Beltramello, Martina; Guarino, Barbara; Dang, Ha; de Melo, Guilherme Dias; Pinto, Dora; Sprouse, Kaitlin; Scheaffer, Suzanne M; Bassi, Jessica; Silacci-Fregni, Chiara; Muoio, Francesco; Dini, Marco; Vincenzetti, Lucia; Acosta, Rima; Johnson, Daisy; Subramanian, Sambhavi; Saliba, Christian; Giurdanella, Martina; Lombardo, Gloria; Leoni, Giada; Culap, Katja; McAlister, Carley; Rajesh, Anushka; Dellota, Exequiel; Zhou, Jiayi; Farhat, Nisar; Bohan, Dana; Ceschi, Alessandro; et al (2023). Neutralization, effector function and immune imprinting of Omicron variants. Nature, 621(7979):592-601.
Noseda, Roberta; Franchi, Matteo; Pagnamenta, Alberto; Müller, Laura; Dines, Alison M; Giraudon, Isabelle; Heyerdahl, Fridtjof; Eyer, Florian; Hovda, Knut Erik; Liechti, Matthias E; Miró, Òscar; Vallersnes, Odd Martin; Yates, Christopher; Dargan, Paul I; Wood, David M; Ceschi, Alessandro (2023). Determinants of Admission to Critical Care Following Acute Recreational Drug Toxicity: A Euro-DEN Plus Study. Journal of Clinical Medicine, 12(18):5970.
Grove, Jane I; Stephens, Camilla; Lucena, M Isabel; Andrade, Raúl J; Weber, Sabine; Gerbes, Alexander; Bjornsson, Einar S; Stirnimann, Guido; Daly, Ann K; Hackl, Matthias; Khamina-Kotisch, Kseniya; Marin, Jose J G; Monte, Maria J; Paciga, Sara A; Lingaya, Melanie; Forootan, Shiva S; Goldring, Christopher E P; Poetz, Oliver; Lombaard, Rudolf; Stege, Alexandra; Bjorrnsson, Helgi K; Robles-Diaz, Mercedes; Li, Dingzhou; Tran, Thi Dong Binh; Ramaiah, Shashi K; Samodelov, Sophia L; Kullak-Ublick, Gerd A; Aithal, Guruprasad P (2023). Study design for development of novel safety biomarkers of drug-induced liver injury by the translational safety biomarker pipeline (TransBioLine) consortium: a study protocol for a nested case–control study. Diagnostic and Prognostic Research, 7(1):18.
Sidorenko, Nick; Chung, Hui-Kuan; Grueschow, Marcus; Quednow, Boris B; Hayward-Könnecke, Helen; Jetter, Alexander; Tobler, Philippe N (2023). Acetylcholine and noradrenaline enhance foraging optimality in humans. Proceedings of the National Academy of Sciences of the United States of America, 120(36):2305596120.
Andrade, Raúl J; Aithal, Guruprasad P; de Boer, Ynto S; Liberal, Rodrigo; Gerbes, Alexander; Regev, Arie; Terziroli Beretta-Piccoli, Benedetta; Schramm, Christoph; Kleiner, David E; De Martin, Eleonora; Kullak-Ublick, Gerd A; Stirnimann, Guido; Devarbhavi, Harshad; Vierling, John M; Manns, Michael P; Sebode, Marcial; Londoño, Maria Carlota; Avigan, Mark; Robles-Diaz, Mercedes; García-Cortes, Miren; Atallah, Edmond; Heneghan, Michael; Chalasani, Naga; Trivedi, Palak J; Hayashi, Paul H; Taubert, Richard; Fontana, Robert J; Weber, Sabine; Oo, Ye Htun; Zen, Yoh; et al; IAIHG Consortium; EASL DHILI Consortium (2023). Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report. Journal of Hepatology, 79(3):853-866.
Stermann, Julia; Damke, Beat; Wegener, Susanne; Weber, Konrad P; Far, Elmira; Nowak, Karl Andreas; Ortland, Imke (2023). Leukopenie: eine seltene unerwünschte Arzneimittelwirkung unter Amitriptylin. Swiss Medical Forum, 23(16):1018-1020.
Noseda, Roberta; Rea, Federico; Pagnamenta, Alberto; Agazzi, Pamela; Bianco, Giovanni; Sihabdeen, Shairin; Seiffge, David; Michel, Patrik; Nedeltchev, Krassen; Bonati, Leo; Kägi, Georg; Niederhauser, Julien; Nyffeler, Thomas; Luft, Andreas; Wegener, Susanne; Schelosky, Ludwig; Medlin, Friedrich; Rodic, Biljana; Peters, Nils; Renaud, Susanne; Mono, Marie-Luise; Carrera, Emmanuel; Fischer, Urs; Ceschi, Alessandro; Cereda, Carlo Walter (2023). Sex Differences in Outcomes of Intravenous Thrombolysis in Acute Ischemic Stroke Patients with Preadmission Use of Antiplatelets. CNS Drugs, 37(4):351-361.
Soutschek, Alexander; Jetter, Alexander; Tobler, Philippe N (2023). Toward a unifying account of dopamine’s role in cost-benefit decision making. Biological Psychiatry: Global Open Science, 3(2):179-186.
Noseda, Roberta; Bedussi, Francesca; Gobbi, Claudio; Ceschi, Alessandro; Zecca, Chiara (2023). Safety profile of monoclonal antibodies targeting the calcitonin gene-related peptide system in pregnancy: Updated analysis in VigiBase®. Cephalalgia, 43(4):033310242311580.
Gui, Ting; Chen, Qingfa; Li, Jiangsong; Lu, Ke; Li, Chen; Xu, Bin; Chen, Yang; Men, Jingwen; Kullak-Ublick, Gerd A; Wang, Weihua; Gai, Zhibo (2023). Astragaloside IV alleviates 1-deoxysphinganine-induced mitochondrial dysfunction during the progression of chronic kidney disease through p62-Nrf2 antioxidant pathway. Frontiers in Pharmacology, 14:1092475.
Maane, Max; Xiu, Fangrui; Bellstedt, Peter; Kullak-Ublick, Gerd A; Visentin, Michele (2023). Characterization of ligand-induced thermal stability of the human organic cation transporter 2 (OCT2). Frontiers in Pharmacology, 14:1154213.
Kastrinou Lampou, Vlasia; Poller, Birk; Huth, Felix; Fischer, Audrey; Kullak-Ublick, Gerd A; Arand, Michael; Schadt, Heiko S; Camenisch, Gian (2023). Novel insights into bile acid detoxification via CYP, UGT and SULT enzymes. Toxicology in Vitro, 87:105533.
Gai, Zhibo; Samodelov, Sophia L; Alecu, Irina; Hornemann, Thorsten; Grove, Jane I; Aithal, Guruprasad P; Visentin, Michele; Kullak-Ublick, Gerd A (2023). Plasma Sphingoid Base Profiles of Patients Diagnosed with Intrinsic or Idiosyncratic Drug-induced Liver Injury. International Journal of Molecular Sciences, 24(3):3013.
Visentin, Michele (2023). The Role of Organic Cation Transporters in the Pharmacokinetics, Pharmacodynamics and Drug-Drug Interactions of Tyrosine Kinase Inhibitors. International Journal of Molecular Sciences, 24(3):2101.
Björnsson, Einar S; Stephens, Camilla; Atallah, Edmond; Robles-Diaz, Mercedes; Alvarez-Alvarez, Ismael; Gerbes, Alexander; Weber, Sabine; Stirnimann, Guido; Kullak-Ublick, Gerd; Cortez‐Pinto, Helena; Grove, Jane I; Lucena, M Isabel; Andrade, Raul J; Aithal, Guruprasad P (2023). A new framework for advancing in drug-induced liver injury research: The Prospective European DILI Registry. Liver International, 43(1):115-126.
Marzi, Roberta; Bassi, Jessica; Silacci-Fregni, Chiara; Bartha, Istvan; Muoio, Francesco; Culap, Katja; Sprugasci, Nicole; Lombardo, Gloria; Saliba, Christian; Cameroni, Elisabetta; Cassotta, Antonino; Low, Jun Siong; Walls, Alexandra C; McCallum, Matthew; Tortorici, M Alejandra; Bowen, John E; Dellota, Exequiel A; Dillen, Josh R; Czudnochowski, Nadine; Pertusini, Laura; Terrot, Tatiana; Lepori, Valentino; Tarkowski, Maciej; Riva, Agostino; Biggiogero, Maira; Franzetti-Pellanda, Alessandra; Garzoni, Christian; Ferrari, Paolo; Ceschi, Alessandro; Giannini, Olivier; et al (2023). Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape. iScience, 26(1):105726.
Maane, Max. Characterization of ligand-induced thermal stability of the human organic cation transporter 2 (OCT2). 2023, University of Zurich, Faculty of Medicine.
Giovannoni, Luis Lorenzo. Developing a Model for Quantifying QTc-Prolongation Risk to Enhance Medication Safety Assessment: A Retrospective Analysis. 2023, University of Zurich, Faculty of Medicine.
Noseda, Roberta; Müller, Laura; Bedussi, Francesca; Fusaroli, Michele; Raschi, Emanuel; Ceschi, Alessandro (2022). Immune Checkpoint Inhibitors and Pregnancy: Analysis of the VigiBase® Spontaneous Reporting System. Cancers, 15:173.
Heuer, Christine; Streit, Anne-Catherine; Sprengel, Kai; Hasler, Rebecca Maria; Ziegenhain, Franziska; Zahorecz, Mia; Jetter, Alexander; Jung, Hans Heinrich (2022). Cobalt intoxication: mitochondrial features and condition. Journal of Neurology, 269(12):6655-6657.
Rausch, Magdalena; Samodelov, Sophia L; Visentin, Michele; Kullak-Ublick, Gerd A (2022). The Farnesoid X Receptor as a Master Regulator of Hepatotoxicity. International Journal of Molecular Sciences, 23(22):13967.
Park, Young-Jun; Pinto, Dora; Walls, Alexandra C; Liu, Zhuoming; De Marco, Anna; Benigni, Fabio; Zatta, Fabrizia; Silacci-Fregni, Chiara; Bassi, Jessica; Sprouse, Kaitlin R; Addetia, Amin; Bowen, John E; Stewart, Cameron; Giurdanella, Martina; Saliba, Christian; Guarino, Barbara; Schmid, Michael A; Franko, Nicholas M; Logue, Jennifer K; Dang, Ha V; Hauser, Kevin; di Iulio, Julia; Rivera, William; Schnell, Gretja; Rajesh, Anushka; Zhou, Jiayi; Farhat, Nisar; Kaiser, Hannah; Montiel-Ruiz, Martin; Noack, Julia; et al; Ferrari, Paolo; Ceschi, Alessandro; Giannini, Olivier; de Melo, Guilherme Dias; Lanzavecchia, Antonio; Piccoli, Luca; Pizzuto, Matteo Samuele; Corti, Davide (2022). Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. Science, 378(6620):619-627.
Park, Young-Jun; Pinto, Dora; Walls, Alexandra C; Liu, Zhuoming; De Marco, Anna; Benigni, Fabio; Zatta, Fabrizia; Silacci-Fregni, Chiara; Bassi, Jessica; Sprouse, Kaitlin R; Addetia, Amin; Bowen, John E; Stewart, Cameron; Giurdanella, Martina; Saliba, Christian; Guarino, Barbara; Schmid, Michael A; Franko, Nicholas M; Logue, Jennifer K; Dang, Ha V; Hauser, Kevin; di Iulio, Julia; Rivera, William; Schnell, Gretja; Rajesh, Anushka; Zhou, Jiayi; Farhat, Nisar; Kaiser, Hannah; Montiel-Ruiz, Martin; Noack, Julia; et al; Ferrari, Paolo; Ceschi, Alessandro; Giannini, Olivier; De Melo, Guilherme Dias; Lanzavecchia, Antonio; Piccoli, Luca; Pizzuto, Matteo Samuele; Corti, Davide (2022). Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. bioRxiv 491108, Cold Spring Harbor Laboratory.
Bakos, Éva; Német, Orsolya; Kucsma, Nóra; Tőkési, Natália; Stieger, Bruno; Rushing, Elisabeth; Tőkés, Anna-Mária; Kele, Péter; Tusnády, Gábor E; Özvegy-Laczka, Csilla (2022). Cloning and characterization of a novel functional organic anion transporting polypeptide 3A1 isoform highly expressed in the human brain and testis. Frontiers in Pharmacology, 13:958023.
Guri, Yakir; Vosbeck, Jürg; Dickenmann, Michael; Jetter, Alexander; Bernsmeier, Christine (2022). Exacerbation of familial intrahepatic cholestasis in conjunction with COVID-19 vaccination. Journal of Hepatology, 77(3):872-874.
Scherler, Martin; Jetter, Alexander; Ortland, Imke (2022). Lippenschwellung, Gingivahyperplasie und Induration der Wangenmukosa. Swiss Medical Forum, 22(33-34):552-554.
Low, Jun Siong; Jerak, Josipa; Tortorici, M Alejandra; McCallum, Matthew; Pinto, Dora; Cassotta, Antonino; Foglierini, Mathilde; Mele, Federico; Abdelnabi, Rana; Weynand, Birgit; Noack, Julia; Montiel-Ruiz, Martin; Bianchi, Siro; Benigni, Fabio; Sprugasci, Nicole; Joshi, Anshu; Bowen, John E; Stewart, Cameron; Rexhepaj, Megi; Walls, Alexandra C; Jarrossay, David; Morone, Diego; Paparoditis, Philipp; Garzoni, Christian; Ferrari, Paolo; Ceschi, Alessandro; Neyts, Johan; Purcell, Lisa A; Snell, Gyorgy; Corti, Davide; Lanzavecchia, Antonio; Veesler, David; Sallusto, Federica (2022). ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies. Science, 377(6607):735-742.
Liu, Hongtao; Irobalieva, Rossitza N; Bang-Sørensen, Rose; Nosol, Kamil; Mukherjee, Somnath; Agrawal, Parth; Stieger, Bruno; Kossiakoff, Anthony A; Locher, Kaspar P (2022). Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver. Cell Research, 32(8):773-776.
Epistolio, Samantha; Ramelli, Giulia; Ottaviano, Margaret; Crupi, Emanuele; Marandino, Laura; Biggiogero, Maira; Maida, Pier Andrea; Ruinelli, Lorenzo; Vogl, Ursula; Mangan, Dylan; Pascale, Mariarosa; Cantù, Marco; Ceschi, Alessandro; Bernasconi, Enos; Mazzucchelli, Luca; Catapano, Carlo; Alimonti, Andrea; Garzoni, Christian; Gillessen Sommer, Silke; Stefanini, Federico Mattia; Franzetti-Pellanda, Alessandra; Frattini, Milo; Pereira Mestre, Ricardo (2022). P1245 Polymorphic Variants of HSD3B1 Gene Confer Different Outcome in Specific Subgroups of Patients Infected With SARS-CoV-2. Frontiers in Medicine, 8:793728.
Wang, Dongdong; Huang, Jiansheng; Gui, Ting; Yang, Yaxin; Feng, Tingting; Tzvetkov, Nikolay T; Xu, Tao; Gai, Zhibo; Zhou, Ying; Zhang, Jingjie; Atanasov, Atanas G (2022). SR-BI as a target of natural products and its significance in cancer. Seminars in Cancer Biology, 80:18-38.
Cameroni, Elisabetta; Bowen, John E; Rosen, Laura E; Saliba, Christian; Zepeda, Samantha K; Culap, Katja; Pinto, Dora; VanBlargan, Laura A; De Marco, Anna; di Iulio, Julia; Zatta, Fabrizia; Kaiser, Hannah; Noack, Julia; Farhat, Nisar; Czudnochowski, Nadine; Havenar-Daughton, Colin; Sprouse, Kaitlin R; Dillen, Josh R; Powell, Abigail E; Chen, Alex; Maher, Cyrus; Yin, Li; Sun, David; Soriaga, Leah; Bassi, Jessica; Silacci-Fregni, Chiara; Gustafsson, Claes; Franko, Nicholas M; Logue, Jenni; Iqbal, Najeeha Talat; et al; Ceschi, Alessandro; Ferrari, Paolo; Cippà, Pietro E; Franzetti-Pellanda, Alessandra; Garzoni, Christian; Piccoli, Luca; Pizzuto, Matteo Samuele; Lanzavecchia, Antonio (2022). Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift. Nature, 602(7898):664-670.
Di Serio, Clelia; Cippà, Pietro; Ceschi, Alessandro; Ferrari, Paolo (2022). Reply to Gremese et al: Statistical reasoning to evaluate treatment effects when data are collected with lack of design: Covid-19 experience. Proceedings of the National Academy of Sciences of the United States of America, 119(7):e2103168119.
Lüscher, Benjamin P; Albrecht, Christiane; Stieger, Bruno; Surbek, Daniel V; Baumann, Marc U (2022). Glucose Transporter 9 (GLUT9) Plays an Important Role in the Placental Uric Acid Transport System. Cells, 11(4):633.
Bassi, Jessica; Giannini, Olivier; Silacci-Fregni, Chiara; Pertusini, Laura; Hitz, Paolo; Terrot, Tatiana; Franzosi, Yves; Muoio, Francesco; Saliba, Christian; Meury, Marcel; Dellota, Exequiel A; Dillen, Josh R; Hernandez, Patrick; Czudnochowski, Nadine; Cameroni, Elisabetta; Beria, Nicola; Ventresca, Mariangela; Badellino, Alberto; Lavorato-Hadjeres, Soraya; Lecchi, Elisabetta; Bonora, Tecla; Mattiolo, Matteo; Trinci, Guido; Garzoni, Daniela; Bonforte, Giuseppe; Forni-Ogna, Valentina; Giunzioni, Davide; Berwert, Lorenzo; Gupta, Ravindra K; Ferrari, Paolo; Ceschi, Alessandro; Cippà, Pietro; Corti, Davide; Lanzavecchia, Antonio; Piccoli, Luca (2022). Poor neutralization and rapid decay of antibodies to SARS-CoV-2 variants in vaccinated dialysis patients. PLoS ONE, 17(2):e0263328.
Han, Chao; Zheng, Juan; Wang, Fengyi; Lu, Qingyang; Chen, Qingfa; Hu, Ankang; Visentin, Michele; Kullak-Ublick, Gerd A; Gai, Zhibo; Chu, Lei (2022). The Role of NF-kB in the Downregulation of Organic Cation Transporter 2 Expression and Renal Cation Secretion in Kidney Disease. Frontiers in Medicine, 8:800421.
Grossenbacher, Philipp; Essers, Maria C; Moser, Joël; Singer, Simon A; Häusler, Stephanie; Stieger, Bruno; Rougier, Jean-Sébastien; Lochner, Martin (2022). Bioorthogonal site-selective conjugation of fluorescent dyes to antibodies: method and potential applications. RSC Advances, 12(44):28306-28317.
Landolt, Tanja; Ortland, Imke (2022). Kontrastmittelinduzierte Neurotoxizität - DE_Vigilance-News-Edition_29_2022. Bern: Swissmedic Journal.
Marzi, Roberta; Bassi, Jessica; Silacci-Fregni, Chiara; Bartha, Istvan; Muoio, Francesco; Culap, Katja; Sprugasci, Nicole; Lombardo, Gloria; Saliba, Christian; Cameroni, Elisabetta; Cassotta, Antonino; Low, Jun Siong; Walls, Alexandra C; McCallum, Matthew; Tortorici, M Alejandra; Bowen, John E; Dellota, Exequiel A; Dillen, Josh R; Czudnochowski, Nadine; Pertusini, Laura; Terrot, Tatiana; Lepori, Valentino; Tarkowski, Maciej; Riva, Agostino; Biggiogero, Maira; Pellanda, Alessandra Franzetti; Garzoni, Christian; Ferrari, Paolo; Ceschi, Alessandro; Giannini, Olivier; Sallusto, Federica; Lanzavecchia, Antonio; Corti, Davide; Piccoli, Luca; et al (2022). Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape. bioRxiv 509852, Cold Spring Harbor Laboratory.
Landolt, Tanja; Ortland, Imke (2022). Multiple Sklerose und COVID-19-Impfstoffe - DE_Vigilance-News-Edition_28_2022. Bern: Swissmedic Journal.
Schimmer, Roman R. TP53 mutations confer resistance to hypomethylating agents and BCL-2 inhibition in myeloid neoplasms. 2022, University of Zurich, Faculty of Medicine.
Sutter, Morena Leandra. The role of cholesterol recognition (CARC/CRAC) mirror codes in the allosterism of the human organic cation transporter 2 (OCT2, SLC22A2). 2022, University of Zurich, Faculty of Medicine.
Ndayisaba, Gilles; Yeka, Adoke; Asante, Kwaku Poku; et al; Kullak-Ublick, Gerd A; Gandhi, Preetam (2021). Hepatic safety and tolerability of cipargamin (KAE609), in adult patients with Plasmodium falciparum malaria: a randomized, phase II, controlled, dose-escalation trial in sub-Saharan Africa. Malaria Journal, 20(1):478.
Sutter, Morena Leandra; Console, Lara; Fahner, Anne-Fleur; Samodelov, Sophia L; Gai, Zhibo; Ciarimboli, Giuliano; Indiveri, Cesare; Kullak-Ublick, Gerd A; Visentin, Michele (2021). The role of cholesterol recognition (CARC/CRAC) mirror codes in the allosterism of the human organic cation transporter 2 (OCT2, SLC22A2). Biochemical Pharmacology, 194:114840.
Atallah, Edmond; Freixo, Cristiana; Alvarez-Alvarez, Ismael; Cubero, F J; Gerbes, Alexander L; Kullak-Ublick, Gerd A; Aithal, Guruprasad P (2021). Biomarkers of idiosyncratic drug-induced liver injury (DILI) - a systematic review. Expert Opinion on Drug Metabolism & Toxicology, 17(11):1327-1343.
Kullak-Ublick, Gerd A (2021). Nukleäre Rezeptoren beim hepatischen und intestinalen Medikamententransport. Drug Research, 71:S13-S14.
Naidu, Roopa J; Kullak-Ublick, Gerd A (2021). Leberschaden bei Komplementärmedizin. Schweizer Zeitschrift für Ernährungsmedizin (SZE), 2021(4):13-16.
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Gessler Grenacher, Mirjam Claudia. Epidemiologie der Vergiftungsmortalität in der Schweiz von 1997 bis 2008. 2020, University of Zurich, Faculty of Medicine.
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Karrer, Julia E; Giovannoni, Luis; Kullak-Ublick, Gerd A; Weiler, Stefan (2019). Pharmacovigilance in ophthalmology in Switzerland: an analysis of the most frequently reported ocular adverse drug reactions within the last 25 years. Swiss Medical Weekly, 149(25-26):w20085.
Sigaroudi, Ali; Jetter, Alexander; Mueller, Thomas F; Kullak-Ublick, Gerd A; Weiler, Stefan (2019). Severe reduction in tacrolimus concentrations with concomitant metamizole (dipyrone) therapy in transplant patients. European Journal of Clinical Pharmacology, 75(6):869-872.
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Jaerapong, Nattharat; Jamil, Qurratul Ain; Riha, Juliane; Milovanovic, Daniela; Krupitza, Georg; Stieger, Bruno; Jarukomjorn, Kanokwan; Jäger, Walter (2019). Organic anion‑transporting polypeptides contribute to the uptake of curcumin and its main metabolites by human breast cancer cells: Impact on antitumor activity. Oncology Reports, 41(4):2558-2566.
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Antener, Enrica Barbara. Die Rolle von Organic-Anion-Transporting-Polypeptides (OATPs) in der Wirkung von Lokalanästhetika. 2019, University of Zurich, Faculty of Medicine.
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El Saadany, Tämer Philip. MicroRNA-206 modulates the hepatic expression of the organic anion-transporting polypeptide 1B1. 2019, University of Zurich, Faculty of Medicine.
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Diaz-Cañestro, Candela; Merlini, Mario; Bonetti, Nicole R; Liberale, Luca; Wüst, Patricia; Briand-Schumacher, Sylvie; Klohs, Jan; Costantino, Sara; Miranda, Melroy; Schoedon-Geiser, Gabriele; Kullak-Ublick, Gerd A; Akhmedov, Alexander; Paneni, Francesco; Beer, Jürg H; Lüscher, Thomas F; Camici, Giovanni G (2018). Sirtuin 5 as a novel target to blunt blood-brain barrier damage induced by cerebral ischemia/reperfusion injury. International Journal of Cardiology, 260:148-155.
Bank, Martina; Weiler, Stefan (2018). Blutungen bei Vitamin-K-Mangel unter Orlistat. Swiss Medical Forum, 18(23):479-481.
Apte, Asmita; Kupferschmidt, Hugo; Weiler, Stefan (2018). Schwäche, Bradykardie, Sehstörungen, Hyperkaliämie unter Digoxin. Swiss Medical Forum, 18(22):460-462.
Kupferschmidt, Hugo; Weiler, Stefan (2018). Akutes Leberversagen nach wiederholter Paracetamoleinnahme. Swiss Medical Forum, 18(21):437-439.
Rudolph, Annette; Weiler, Stefan (2018). Palpitationen unter Xylometazolin. Swiss Medical Forum, 18(19-20):415-416.
Kaserer, Alexander; Schedler, Andreas; Jetter, Alexander; Seifert, Burkhardt; Spahn, Donat R; Stein, Philipp; Studt, Jan-Dirk (2018). Risk Factors for Higher-than-Expected Residual Rivaroxaban Plasma Concentrations in Real-Life Patients. Thrombosis and Haemostasis, 118(05):808-817.
Hübner, Simona T; Bertoli, Raffaela; Rätz Bravo, Alexandra E; Schaueblin, Martina; Haschke, Manuel; Scherer, Kathrin; Ceschi, Alessandro; Leuppi-Taegtmeyer, Anne B (2018). C-Reactive Protein and Procalcitonin in Case Reports of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome. International Archives of Allergy and Immunology, 176(1):44-54.
Butter, Matthias; Weiler, Stefan; Biedermann, Luc; Scharl, Michael; Rogler, Gerhard; Bischoff-Ferrari, Heike A; Misselwitz, Benjamin (2018). Clinical manifestations, pathophysiology, treatment and outcome of inflammatory bowel diseases in older people. Maturitas, 110:71-78.
Rudolph, Annette; Weiler, Stefan (2018). Unruhe, Unwohlsein und Zittern bei Opioid-Entzugssyndrom. Swiss Medical Forum, 18(1314):295-296.
Sekaggya-Wiltshire, Christine; von Braun, Amrei; Lamorde, Mohammed; Ledergerber, Bruno; Buzibye, Allan; Henning, Lars; Musaazi, Joseph; Gutteck, Ursula; Denti, Paolo; de Kock, Miné; Jetter, Alexander; Byakika-Kibwika, Pauline; Eberhard, Nadia; Matovu, Joshua; Joloba, Moses; Muller, Daniel; Manabe, Yukari C; Kamya, Moses R; Corti, Natascia; Kambugu, Andrew; Castelnuovo, Barbara; Fehr, Jan S (2018). Delayed Sputum Culture Conversion in Tuberculosis-Human Immunodeficiency Virus-Coinfected Patients With Low Isoniazid and Rifampicin Concentrations. Clinical Infectious Diseases, 67(5):708-716.
Lemmen, Silvia; Weiler, Stefan (2018). Extrapyramidale Symptome unter Metoclopramid. Swiss Medical Forum, 18(10):220-221.
Roos, Noëmi; Weiler, Stefan (2018). Hemiballismus unter Cinnarizin. Swiss Medical Forum, 18(07):145-146.
Fuchs, Joan; Martin, Nadine C; Rauber-Lüthy, Christine (2018). A verified bite by Heteroscodra maculata (Togo starburst or ornamental baboon tarantula) resulting in long-lasting muscle cramps. Clinical Toxicology, 56(7):675-676.
Sargiacomo, Camillo; El-Kehdy, Hoda; Pourcher, Guillaume; Stieger, Bruno; Najimi, Mustapha; Sokal, Etienne (2018). Age-dependent glycosylation of the sodium taurocholate cotransporter polypeptide: From fetal to adult human livers. Hepatology Communications, 2(6):693-702.
Jödicke, Annika M; Curkovic, Ivanka; Zellweger, Urs; Tomka, Ivan T; Neuer, Thomas; Kullak-Ublick, Gerd A; Roos, Malgorzata; Egbring, Marco (2018). Analysis of drug-drug interactions in Swiss claims data using tizanidine and ciprofloxacin as a prototypical contraindicated combination. The Annals of Pharmacotherapy, 52(10):983-991.
Roos, Noëmi; Weiler, Stefan (2018). Beidseitige Achillodynie unter Ciprofloxacin. Swiss Medical Forum, 18(06):123-124.
Schadt, Heiko S; Wolf, Armin; Mahl, Joerg Andreas; Wuersch, Kuno; Couttet, Philippe; Schwald, Marianne; Fischer, Audrey; Lienard, Mathilde; Emotte, Corinne; Teng, Chi-Hse; Skuba, Elizabeth; Richardson, Terrilyn A; Manenti, Luigi; Weiss, Andreas; Graus Porta, Diana; Fairhurst, Robin A; Kullak-Ublick, Gerd A; Chibout, Salah-Dine; Pognan, Francois; Kluwe, William; Kinyamu-Akunda, Jacqueline (2018). Bile acid sequestration by cholestyramine mitigates FGFR4 inhibition-induced ALT elevation. Toxicological Sciences, 163(1):265-278.
Gantenbein, Pascal. Cellular and molecular mechanisms of colistin-induced nephrotoxicity. 2018, University of Zurich, Faculty of Medicine.
Visentin, Michele; Lenggenhager, Daniela; Gai, Zhibo; Kullak-Ublick, Gerd A (2018). Drug-induced bile duct injury. Biochimica et Biophysica Acta, 1864(4):1498-1506.
Müller, M; Ricklin, M E; Weiler, Stefan; Exadaktylos, A K; Arampatzis, Spyridon (2018). Emergency medicine in the extreme geriatric era: A retrospective analysis of patients aged in their mid 90s and older in the emergency department. Geriatrics & Gerontology International, 18(3):415-420.
Visentin, Michele; Torozi, Angelo; Gai, Zhibo; Hausler, Stephanie; Li, Chao; Hiller, Christian; Schraml, Peter H; Moch, Holger; Kullak-Ublick, Gerd A (2018). Fluorocholine transport mediated by the organic cation transporter 2 (OCT2,SLC22A2): implication for imaging of kidney tumors. Drug Metabolism and Disposition, 46(8):1129-1136.
Tournier, Nicolas; Stieger, Bruno; Langer, Oliver (2018). Imaging techniques to study drug transporter function in vivo. Pharmacology & Therapeutics, 189:104-122.
Del Giorno, Rosaria; Ceschi, Alessandro; Pironi, Michela; Zasa, Anna; Greco, Angela; Gabutti, Luca (2018). Multifaceted intervention to curb in-hospital over-prescription of proton pump inhibitors: A longitudinal multicenter quasi-experimental before-and-after study. European Journal of Internal Medicine, 50:52-59.
Rau, Monika; Schmitt, Johannes; Berg, Thomas; Kremer, Andreas E; Stieger, Bruno; Spanaus, Katharina; Bengsch, Bertram; Romero, Marta R; Marin, Jose J; Keitel, Verena; Klinker, Hartwig; Tony, Hans-Peter; Müllhaupt, Beat; Geier, Andreas (2018). Serum IP-10 levels and increased DPPIV activity are linked to circulating CXCR3+ T cells in cholestatic HCV patients. PLoS ONE, 13(12):e0208225.
Willkommen, Desiree; Lucio, Marianna; Schmitt-Kopplin, Philippe; Gazzaz, Malaz; Schroeter, Michael; Sigaroudi, Ali; Michalke, Bernhard (2018). Species fractionation in a case-control study concerning Parkinson’s disease: Cu-amino acids discriminate CSF of PD from controls. Journal of Trace Elements in Medicine and Biology, 49:164-170.
Cornely, Oliver A; Weiler, Stefan (2018). Systemische Mykosen. In: Herold, Gerd. Innere Medizin 2019. Köln: Herold, Gerd (Verlag), 387-390.
Gai, Zhibo; Visentin, Michele; Gui, Ting; Zhao, Lin; Thasler, Wolfgang E; Hausler, Stephanie; Hartling, Ivan; Cremonesi, Alessio; Hiller, Christian; Kullak-Ublick, Gerd A (2018). The effects of farnesoid X receptor activation on arachidonic acid metabolism, NF-kB signaling and hepatic inflammation. Molecular Pharmacology, 94(2):802-811.
Reiber, Claudine. Therapeutic drug monitoring of daptomycin : a retrospective monocentric analysis. 2018, University of Zurich, Faculty of Medicine.
Weber, Nina T; Sigaroudi, Ali; Ritter, Alexander; Boss, Andreas; Lehmann, Kuno; Goodman, David; Farese, Stefan; Weiler, Stefan; Mueller, Thomas F (2017). Intractable ascites associated with mycophenolate in a simultaneous kidney-pancreas transplant patient: a case report. BMC Nephrology, 18(1):360.
Essers, Dirk; Weiler, Stefan (2017). Die Statin-assoziierte immun-mediierte nekrotisierende Myopathie (IMNM) – Neue Schweizer Fälle. Vigilance-News: Swissmedic • Schweizerisches Heilmittelinstitut.
Visentin, Michele; Gai, Zhibo; Torozi, Angelo; Hiller, Christian; Kullak-Ublick, Gerd A (2017). Colistin is substrate of the carnitine/organic cation transporter 2 (OCTN2, SLC22A5). Drug Metabolism and Disposition, 45(12):1240-1244.
Cornely, Oliver A; Weiler, Stefan (2017). Systemische Mykosen. In: Herold, Gerd. Innere Medizin 2018. Köln: Gerd Herold Verlag, 388-391.
Sekaggya-Wiltshire, Christine; Castelnuovo, Barbara; von Braun, Amrei; Musaazi, Joseph; Muller, Daniel; Buzibye, Allan; Gutteck, Ursula; Henning, Lars; Ledergerber, Bruno; Corti, Natascia; Lamorde, Mohammed; Fehr, Jan; Kambugu, Andrew (2017). Cohort profile of a study on outcomes related to tuberculosis and antiretroviral drug concentrations in Uganda: design, methods and patient characteristics of the SOUTH study. BMJ Open, 7(9):e014679.
Rudolph, Annette; Weiler, Stefan (2017). Duodenalulkusperforation unter Naproxen. Swiss Medical Forum, 17(36):756-759.
Rudolph, Annette; Weiler, Stefan (2017). Surdosage après erreur d’utilisation de Transtec®. Swiss Medical Forum, 17(38):806-807.
Rudolph, Annette; Weiler, Stefan (2017). Überdosierung nach Anwendungsfehler von Transtec®. Swiss Medical Forum, 17(38):806-807.
Weiler, Stefan; Jetter, A (2017). Panzytopenie unter Methotrexat. Swiss Medical Forum, 17(28-29):594-596.
Weiler, Stefan; Kullak-Ublick, G A (2017). Pharmacovigilance: von «primum non nocere» zu «qua nocent docent». Swiss Medical Forum, 17(28-29):590-593.
Meyer, S; Hartmann, F; Stein, P; Lenherr, R; Fuchs, J; Spahn, D R (2017). Massive coagulopathy caused by the bite of a Crotalus basiliscus snake. Anaesthesia cases:n/a.
Essers, Dirk; Weiler, Stefan (2017). Die Statin-assoziierte immun-mediierte nekrotisierende Myopathie (IMNM). Swissmedic: Bern.
Essers, Dirk; Weiler, Stefan (2017). Myopathies nécrosantes à médiation immune (IMNM) sous statines. Swissmedic: Bern.
Essers, Dirk; Weiler, Stefan (2017). Statin-associated immune-mediated necrotising myopathy (IMNM). Swissmedic: Bern.
Boström, Adrian E; Ciuculete, Diana-Maria; Attwood, Misty; Krattinger, Regina; Nikontovic, Lamia; Titova, Olga E; Kullak-Ublick, Gerd A; Mwinyi, Jessica; Schiöth, Helgi B (2017). A MIR4646 associated methylation locus is hypomethylated in adolescent depression. Journal of Affective Disorders, 220:117-128.
Urry, Emily; Jetter, Alexander; Holst, Sebastian C; Berger, Wolfgang; Spinas, Giatgen A; Langhans, Wolfgang; Landolt, Hans-Peter (2017). A case-control field study on the relationships among type 2 diabetes, sleepiness and habitual caffeine intake. Journal of Psychopharmacology, 31(2):233-242.
Hofer, Katharina E; Faber, Katrin; Müller, Daniel M; Hauffe, Till; Wenger, Urs; Kupferschmidt, Hugo; Rauber-Lüthy, Christine (2017). Acute Toxicity Associated With the Recreational Use of the Novel Psychoactive Benzofuran N-methyl-5-(2 aminopropyl)benzofuran. Annals of emergency medicine, 69(1):79-82.
Nicoletti, Paola; Aithal, Guruprasad P; Bjornsson, Einar S; Andrade, Raul J; Sawle, Ashley; Arrese, Marco; Barnhart, Huiman X; Bondon-Guitton, Emmanuelle; Hayashi, Paul H; Bessone, Fernando; Carvajal, Alfonso; Cascorbi, Ingolf; Cirulli, Elizabeth T; Chalasani, Naga; Conforti, Anita; Coulthard, Sally A; Daly, Mark J; Day, Christopher P; Dillon, John F; Fontana, Robert J; Grove, Jane I; Hallberg, Pär; Hernández, Nelia; Ibáñez, Luisa; Kullak-Ublick, Gerd A; Laitinen, Tarja; Larrey, Dominique; Lucena, M Isabel; Maitland-van der Zee, Anke H; Martin, Jennifer H; et al (2017). Association of liver injury from specific drugs, or groups of drugs, with polymorphisms in HLA and other genes in a genome-wide association study. Gastroenterology, 152(5):1078-1089.
Kupferschmidt, Hugo (2017). Die Beurteilung asymptomatischer Patienten mit akuten Vergiftungen. Swiss Medical Forum, 17(3):64-65.
Kullak-Ublick, Gerd A; Andrade, Raul J; Merz, Michael; End, Peter; Benesic, Andreas; Gerbes, Alexander L; Aithal, Guruprasad P (2017). Drug-induced liver injury: recent advances in diagnosis and risk assessment. Gut, 66(6):1154-1164.
Fuchs, Joan; Casado Diaz, Jose I; Jud Schefer, Rahel; Rauber-Lüthy, Christine (2017). Expired antivenom: good efficacy in a severely envenomed cat bitten by Sistrurus miliarius miliarius (Carolina Pigmy Rattlesnake). Clinical Toxicology, 55(6):613-614.
Gai, Zhibo; Chu, Lei; Xu, Zhenqiang; Song, Xiaoming; Sun, Dongfeng; Kullak-Ublick, Gerd A (2017). Farnesoid X receptor activation protects the kidney from ischemia-reperfusion damage. Scientific Reports, 7(1):1-16.
Sigaroudi, Ali; Weiler, Stefan (2017). Heparininduzierte Thrombozytopenie Typ II = Thrombopénie induite par l’héparine de type II. Swiss Medical Forum, 17(33):676-677.
Visentin, M; van Rosmalen, B V; Hiller, C; Bieze, M; Hofstetter, L; Verheij, J; Kullak-Ublick, G A; Koepsell, H; Phoa, S S; Tamai, I; Bennink, R J; van Gulik, T M; Stieger, B (2017). Impact of organic cation transporters (OCT-SLC22A) on differential diagnosis of intrahepatic lesions. Drug Metabolism and Disposition, 45(2):166-173.
Chedik, Lisa; Bruyere, Arnaud; Le Vee, Marc; Stieger, Bruno; Denizot, Claire; Parmentier, Yannick; Potin, Sophie; Fardel, Olivier (2017). Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin. PLoS ONE, 12(1):e0169480.
Bruyere, Arnaud; Hubert, Céline; Le Vee, Marc; Chedik, Lisa; Sayyed, Katia; Stieger, Bruno; Denizot, Claire; Parmentier, Yannick; Fardel, Olivier (2017). Inhibition of SLC drug transporter activities by environmental bisphenols. Toxicology in Vitro, 40:34-44.
Stieger, Bruno; Mahdi, Zainab M; Jäger, Walter (2017). Intestinal and hepatocellular transporters: therapeutic effects and drug interactions of herbal supplements. Annual Review of Pharmacology and Toxicology, 57(1):399-416.
Kupferschmidt, Hugo (2017). Koma bei exogenen Intoxikationen. In: Battegay, Edouard. Differenzialdiagnose Innerer Krankheiten : vom Symptom zur Diagnose. Stuttgart: Georg Thieme, 645-649.
Gnädinger, Markus; Conen, Dieter; Herzig, Lilli; Puhan, Milo A; Staehelin, Alfred; Zoller, Marco; Ceschi, Alessandro (2017). Medication incidents in primary care medicine: a prospective study in the Swiss Sentinel Surveillance Network (Sentinella). BMJ Open, 7:e013658.
Stieger, Bruno; Mahdi, Zainab M (2017). Model Systems for Studying the Role of Canalicular Efflux Transporters in Drug-Induced Cholestatic Liver Disease. Journal of Pharmaceutical Sciences, 106(9):2295-2301.
Schenk-Jaeger, Katharina M; Hofer-Lentner, Katharina E; Plenert, Bettina; Eckart, Dagmar; Haberl, Bettina; Schulze, Gabriele; Borchert-Avalone, Janine; Stedtler, Uwe; Pfab, Rudolph (2017). No clinically relevant effects in children after accidental ingestion of Panaeolina foenisecii (lawn mower’s mushroom). Clinical Toxicology, 55(3):217-220.
Baumann, Pierre; Amstutz, Ursula; Jetter, Alexander; Samer, Caroline; Ansari, Marc (2017). Personalisierte Therapie bei Psychopharmaka Pharmacogénomique et thérapie personnalisée = Grundlagen und praktische Hinweise für pharmakogenetische = Tests Notions de base et aspects pratiques à propos de tests pharmacogénétiques. InFo Neurologie & Psychiatrie, 15(6):21-32.
Mayati, Abdullah; Moreau, Amélie; Le Vée, Marc; Stieger, Bruno; Denizot, Claire; Parmentier, Yannick; Fardel, Olivier (2017). Protein Kinases C-Mediated Regulations of Drug Transporter Activity, Localization and Expression. International Journal of Molecular Sciences, 18(4):764.
Brown, Lisa; Kullak-Ublick, G A (2017). Risiko / Benefit-Betrachtung der SGLT-2 Inhibitoren. info@herz+gefäss, (1):17-19.
Nicolaï, Johan; Thevelin, Louise; Bing, Qi; Stieger, Bruno; Chanteux, Hugues; Augustijns, Patrick; Annaert, Pieter (2017). Role of the OATP Transporter Family and a Benzbromarone-SensitiveEfflux Transporter in the Hepatocellular Disposition of Vincristine. Pharmaceutical Research, 34(11):2336-2348.
Lüde, S; Hofer, K; Schenk-Jäger, K; Rauber-Lüthy, C (2017). Sechs tödliche Vergiftungen aufgrund von Medikamenten. PharmaJournal, 23:29-31.
Peta, Valentina; Tse, Chantal; Perazzo, Hugo; Munteanu, Mona; Ngo, Yen; Ngo, An; Ramanujam, Nittia; Verglas, Lea; Mallet, Maxime; Ratziu, Vlad; Thabut, Dominique; Rudler, Marika; Thibault, Vincent; Schuppe-Koistinen, Ina; Bonnefont-Rousselot, Dominique; Hainque, Bernard; Imbert-Bismut, Françoise; Merz, Michael; Kullak-Ublick, Gerd; Andrade, Raul; van Boemmel, Florian; Schott, Eckart; Poynard, Thierry (2017). Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery. PLoS ONE, 12(12):e0189436.
Jödicke, Annika; Dahmke, H; Damke, Beat; Schäublin, M; Kullak-Ublick, G A; Weiler, Stefan (2017). Severe injection site reactions after subcutaneous administration of Sayana®: a retrospective, post-marketing analysis of WHO and Swiss spontaneous pharmacovigilance reports. Swiss Medical Weekly:147:w14432.
Wang, Huaiguo; Li, Jian; Gai, Zhibo; Kullak-Ublick, Gerd A; Liu, Zewei (2017). TNF-α deficiency prevents renal inflammation and oxidative stress in obese mice. Kidney & Blood Pressure Research, 42(3):416-427.
Kupferschmidt, Hugo; Rauber-Lüthy, Christine (2017). Vergiftungen in der Schweiz. Schweizerische Ärztezeitung (SÄZ), 98(11):332-336.
Kupferschmidt, Hugo; Rauber-Lüthy, Christine (2017). Vergiftungen in der Schweiz. Zur Beratungstätigkeit 2016 von Tox Info Suisse. Schweizerische Ärztezeitung (SÄZ), 98(43):1406-1410.
Kupferschmidt, Hugo; Degrandi, Colette; Rauber-Lüthy, Christine (2017). Vergiftungen mit Kohlenmonoxid. Swiss Medical Forum, 17(21-22):471-475.
Fuchs, Joan; Meyer, Andreas; Rauber-Lüthy, Christine (2017). War das «Insekt» wirklich eine Schlange oder doch ein Insekt? Swiss Medical Forum, 17(25):564.
Mayati, Abdullah; Moreau, Amélie; Denizot, Claire; Stieger, Bruno; Parmentier, Yannick; Fardel, Olivier (2017). β2-adrenergic receptor-mediated in vitro regulation of human hepatic drug transporter expression by epinephrine. European Journal of Pharmaceutical Sciences, 106:302-312.
Limani, Perparim; Linecker, Michael; Kron, Philipp; Samaras, Panagiotis; Pestalozzi, Bernhard; Stupp, Roger; Jetter, Alexander; Dutkowski, Philipp; Müllhaupt, Beat; Schlegel, Andrea; Nicolau, Claude; Lehn, Jean-Marie; Petrowsky, Henrik; Humar, Bostjan; Graf, Rolf; Clavien, Pierre-Alain (2016). Development of OXY111A, a novel hypoxia-modifier as a potential antitumor agent in patients with hepato-pancreato-biliary neoplasms - Protocol of a first Ib/IIa clinical trial. BMC Cancer, 16(1):812.
Urry, Emily; Jetter, Alexander; Landolt, Hans-Peter (2016). Assessment of CYP1A2 enzyme activity in relation to type-2 diabetes and habitual caffeine intake. Nutrition & Metabolism, 13:66.
Weiler, Stefan. Clinical Pharmacology of Antimycotic Agents for Systemic Fungal Infections. 2016, University of Zurich, Faculty of Medicine.
Niedrig, David; Krattinger, Regina; Jödicke, Annika; Gött, Carmen; Bucklar, Guido; Russmann, Stefan (2016). Development, implementation and outcome analysis of semi-automated alerts for metformin dose adjustment in hospitalized patients with renal impairment. Pharmacoepidemiology and Drug Safety, 25(10):1204-1209.
Niedrig, D F; Bucklar, G; Fetzer, M; Mächler, S; Gött, C; Russmann, S (2016). Paracetamol overdosing in a tertiary care hospital: implementation and outcome analysis of a preventive alert programme. Journal of Clinical Pharmacy and Therapeutics, 41(5):515-518.
Sayyed, Katia; Vee, Marc Le; Abdel-Razzak, Ziad; Jouan, Elodie; Stieger, Bruno; Denizot, Claire; Parmentier, Yannick; Fardel, Olivier (2016). Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate. Toxicology, 363-364:58-71.
Niedrig, David; Maechler, Sarah; Hoppe, Liesa; Corti, Natascia; Kovari, Helen; Russmann, Stefan (2016). Drug safety of macrolide and quinolone antibiotics in a tertiary care hospital: administration of interacting co-medication and QT prolongation. European Journal of Clinical Pharmacology, 72(7):859-67.
Mahdi, Zainab M; Synal-Hermanns, Uta; Yoker, Aylin; Locher, Kaspar P; Stieger, Bruno (2016). Role of Multidrug Resistance Protein 3 in Antifungal-Induced Cholestasis. Molecular Pharmacology, 90(1):23-34.
Lušin, Tina Trdan; Mrhar, Aleš; Stieger, Bruno; Kristl, Albin; Berginc, Katja; Trontelj, Jurij (2016). Efflux and uptake transporters involved in the disposition of bazedoxifene. European Journal of Drug Metabolism and Pharmacokinetics, 41(3):251-257.
Pokladnikova, Jitka; Meyboom, Ronald H B; Meincke, Ricarda; Niedrig, David; Russmann, Stefan (2016). Allergy-Like Immediate Reactions with Herbal Medicines: A Retrospective Study Using Data from VigiBase(®). Drug Safety, 39(5):455-64.
De Bruyn, Tom; Stieger, Bruno; Augustijns, Patrick F; Annaert, Pieter P (2016). Clearance Prediction of HIV Protease Inhibitors in Man: Role of Hepatic Uptake. Journal of Pharmaceutical Sciences, 105(2):854-863.
Montanari, Floriane; Pinto, Marta; Khunweeraphong, Narakorn; Wlcek, Katrin; Sohail, M Imran; Noeske, Tobias; Boyer, Scott; Chiba, Peter; Stieger, Bruno; Kuchler, Karl; Ecker, Gerhard F (2016). Flagging Drugs That Inhibit the Bile Salt Export Pump. Molecular Pharmaceutics, 13(1):163-171.
Wanek, Thomas; Halilbasic, Emina; Visentin, Michele; Mairinger, Severin; Römermann, Kerstin; Stieger, Bruno; Kuntner, Claudia; Müller, Markus; Langer, Oliver; Trauner, Michael (2016). Influence of 24-Nor-Ursodeoxycholic Acid on Hepatic Disposition of [(18)F]Ciprofloxacin, a Positron Emission Tomography Study in Mice. Journal of Pharmaceutical Sciences, 105(1):106-112.
Niedrig, David F; Gött, Carmen; Fischer, Anja; Müller, Sabrina T; Greil, Waldemar; Bucklar, Guido; Russmann, Stefan (2016). Second-generation antipsychotics in a tertiary care hospital: prescribing patterns, metabolic profiles, and drug interactions. International clinical psychopharmacology, 31(1):42-50.
Egbring, Marco; Far, Elmira; Roos, Malgorzata; Dietrich, Michael; Brauchbar, Mathis; Kullak-Ublick, Gerd A; Trojan, Andreas (2016). A Mobile App to Stabilize Daily Functional Activity of Breast Cancer Patients in Collaboration With the Physician: A Randomized Controlled Clinical Trial. Journal of Medical Internet Research, 18(9):e238.
Lüde, Saskia; Vecchio, Sarah; Sinno-Tellier, Sandra; Dopter, Aymeric; Mustonen, Harriet; Vucinic, Slavica; Jonsson, Birgitta; Müller, Dieter; Veras Gimenez Fruchtengarten, Ligia; Hruby, Karl; De Souza Nascimento, Elizabeth; Di Lorenzo, Chiara; Restani, Patrizia; Kupferschmidt, Hugo; Ceschi, Alessandro (2016). Adverse effects of plant food supplements and plants consumed as food: Results from the poisons centres-based PlantLIBRA study. Phytotherapy Research, 30(6):988-996.
Restani, Patrizia; Di Lorenzo, Chiara; Garcia-Alvarez, Alicia; Badea, Mihaela; Ceschi, Alessandro; Egan, Bernadette; Dima, Lorena; Lüde, Saskia; Maggi, Franco M; Marculescu, Angela; Milà-Villarroel, Raimon; Raats, Monique M; Ribas-Barba, Lourdes; Uusitalo, Liisa; Serra-Majem, Lluís (2016). Adverse effects of plant food supplements self-reported by consumers in the PlantLIBRA survey involving six European countries. PLoS ONE, 11(2):e0150089.
Corti, Natascia. Anti-infective therapy in special patient populations based on therapeutic drug monitoring. 2016, University of Zurich, Faculty of Medicine.
Weiler, Stefan (2016). Antikörperbehandlung. In: Kreuzer, K A; Beyer, J. Hämatologie und Onkologie. Stuttgart: Georg Thieme Verlag, 146-147.
Russmann, S; Kullak-Ublick, G A; Weiler, S; Stoller, R; Egbring, M (2016). Arzneimittelsicherheit. In: Siepmann, T; Kirch, W; Kullak-Ublick, G A. Arzneimitteltherapie : Wirksamkeit - Sicherheit - Praktische Anwendung (2. überarbeitete und erweiterte Auflage). Stuttgart: George Thieme Verlag, 71-99.
Arzneimitteltherapie (2. überarbeitete und erweiterte Auflage). Edited by: Siepmann, T; Kirch, W; Kullak-Ublick, G A (2016). Stuttgart, New York: Georg Thieme Verlag.
Weiler, Stefan; Taegtmeyer, Anne B; Müller, Sabine; Rollason, Victoria; Livio, Francoise; Ceschi, Alessandro; Kullak-Ublick, G A (2016). Ausgewählte Fälle aus den regionalen Pharmacovigilance-Zentren. Swiss Medical Forum, 16(37):757-763.
Niedrig, David Franklin; Hoppe, Liesa; Mächler, Sarah; Russmann, Heike; Russmann, Stefan (2016). Benzodiazepine use during hospitalization: automated identification of potential medication errors and systematic assessment of preventable adverse events. PLoS ONE, 11(10):e0163224.
Krattinger, Regina. Bidirectional Interaction between Farnesoid X Receptor and MicroRNAs. 2016, University of Zurich, Faculty of Science.
Schadt, Heiko S; Wolf, Armin; Pognan, Francois; Chibout, Salah-Dine; Merz, Michael; Kullak-Ublick, Gerd A (2016). Bile acids in drug induced liver injury: Key players and surrogate markers. Clinics and Research in Hepatology and Gastroenterology, 40(3):257-266.
Krattinger, Regina; Boström, Adrian; Lee, Serene M L; Thasler, Wolfgang E; Schiöth, Helgi B; Kullak-Ublick, Gerd A; Mwinyi, Jessica (2016). Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes. Life Sciences, 156:47-56.
Ebner, Lukas; Walti, Laura N; Rauch, Andri; Furrer, Hansjakob; Cusini, Alexia; Meyer, Andreas M J; Weiler, Stefan; Huynh-Do, Uyen; Heverhagen, Johannes; Arampatzis, Spyridon; Christe, Andreas (2016). Clinical Course, Radiological Manifestations, and Outcome of Pneumocystis jirovecii Pneumonia in HIV Patients and Renal Transplant Recipients. PLoS ONE, 11(11):e0164320.
Sigaroudi, Ali; Kullak-Ublick, Gerd A; Weiler, Stefan (2016). Concomitant administration of rifampicin and oxcarbazepine results in a significant decrease of the active MHD metabolite of oxcarbazepine. European Journal of Clinical Pharmacology, 72(3):377-378.
Tarnutzer, A A; Bockisch, C J; Buffone, E; Weiler, S; Bachmann, L M; Weber, K P (2016). Disease-specific sparing of the anterior semicircular canals in bilateral vestibulopathy. Clinical Neurophysiology, 127(8):2791-2801.
Li, Tongzhou. Effect of obesity on the expression of the organic anion transporting polypeptide Oatp1a1 in mouse liver. 2016, University of Zurich, Faculty of Medicine.
Niedrig, David Franklin. Improving hospital drug safety - identification of medication errors and subsequent development, implementation and outcome evaluation of alert algorithms for their targeted prevention. 2016, University of Zurich, Faculty of Medicine.
Weiler, Stefan (2016). Konventionelle Zytostatika. In: Kreuzer, K A; Beyer, J. Hämatologie und Onkologie. Stuttgart: Georg Thieme Verlag, 140-146.
Kullak-Ublick, Gerd A; Gubler, Christoph; Spanaus, Katharina; Ismair, Manfred G; Claro da Silva, Tatiana; Jetter, Alexander (2016). No major effects of vitamin D3 (1,25 dihydroxyvitamin D3) on absorption and pharmacokinetics of folic acid and fexofenadine in healthy volunteers. European Journal of Clinical Pharmacology, 72(7):797-805.
Gai, Zhibo; Visentin, Michele; Hiller, Christian; Krajnc, Evelin; Li, Tongzhou; Zhen, Junhui; Kullak-Ublick, Gerd A (2016). Organic cation transporter 2 overexpression may confer an increased risk of gentamicin-induced nephrotoxicity. Antimicrobial Agents and Chemotherapy, 60(9):5573-5580.
Weiler, Stefan; Russmann, Stefan; Stoller, Rudolf (2016). Pharmakovigilanz. In: Kullak-Ublick, G A; Siepmann, T; Kirch, Wilhelm. Arzneimitteltherapie : Wirksamkeit - Sicherheit - Praktische Anwendung (2. überarbeitete und erweiterte Auflage 2016). Stuttgart: Georg Thieme Verlag, 84-91.
Chaubey, Pururawa Mayank; Hofstetter, Lia; Roschitzki, Bernd; Stieger, Bruno (2016). Proteomic Analysis of the Rat Canalicular Membrane Reveals Expression of a Complex System of P4-ATPases in Liver. PLoS ONE, 11(6):e0158033.
Stieb, Sonja; Riesterer, Oliver; Brüssow, Cornelia; Pestalozzi, Bernhard C; Guckenberger, Matthias; Weiler, Stefan (2016). Radiation recall dermatitis induced by sorafenib : A case study and review of the literature. Strahlentherapie und Onkologie, 195(5):342-348.
Stieger, Bruno; Hagenbuch, Bruno (2016). Recent advances in understanding hepatic drug transport. F1000Research, 5:2465.
Weiler, Stefan; Kullak-Ublick, Gerd A (2016). Risiken bei der Behandlung mit neuen Kinase-Inhibitoren in der Onkologie: Welche Targets haben die «Targeted» Therapien? In: SVV. Medinfo: Mitteilungen zu Themen der Privatversicherten. Zürich: ASA | SVV, 25-40.
Mahdi, Zainab M. Role of MDR3 in drug-induced cholestatic liver injury. 2016, ETH, Faculty of Medicine.
Weiler, Stefan; Cornely, O A (2016). Systemische Mykosen. In: Herold, Gerd. Innere Medizin 2017. Köln: Gerd Herold Verlag, 388-391.
Weiler, Stefan; Stoller, Rudolf; Russmann, Stefan (2016). Unerwünschte Arzneimittelwirkungen (UAW). In: Kullak-Ublick, G A; Siepmann, T; Kirch, Wilhelm. Arzneimitteltherapie : Wirksamkeit - Sicherheit - Praktische Anwendung (2. überarbeitete und erweiterte Auflage). Stuttgart: Georg Thieme Verlag, 76-81.
Dahmke, H; Kullak-Ublick, G A (2016). Update Diuretika. Der Informierte Arzt, 6(9):17-20.
Claro da Silva, Tatiana; Hiller, Christian; Gai, Zhibo; Kullak-Ublick, Gerd A (2016). Vitamin D3 transactivates the zinc and manganese transporter SLC30A10 via the Vitamin D receptor. Journal of Steroid Biochemistry and Molecular Biology, 163:77-87.
Krattinger, Regina; Boström, Adrian; Schiöth, Helgi B; Thasler, Wolfgang E; Mwinyi, Jessica; Kullak-Ublick, Gerd A (2016). microRNA-192 suppresses the expression of the farnesoid X receptor. American Journal Of Physiology. Gastrointestinal And Liver Physiology, 310(11):G1044-G1051.
Patik, Izabel; Kovacsics, Daniella; Német, Orsolya; Gera, Melinda; Várady, György; Stieger, Bruno; Hagenbuch, Bruno; Szakács, Gergely; Özvegy-Laczka, Csilla (2015). Functional expression of the 11 human Organic Anion Transporting Polypeptides in insect cells reveals that sodium fluorescein is a general OATP substrate. Biochemical Pharmacology, 98(4):649-658.
Mayati, Abdullah; Le Vee, Marc; Moreau, Amélie; Jouan, Elodie; Bucher, Simon; Stieger, Bruno; Denizot, Claire; Parmentier, Yannick; Fardel, Olivier (2015). Protein kinase C-dependent regulation of human hepatic drug transporter expression. Biochemical Pharmacology, 98(4):703-717.
Gai, Zhibo; Gui, Ting; Hiller, Christian; Kullak-Ublick, Gerd A (2015). Farnesoid X receptor protects against kidney injury in uninephrectomized obese mice. Journal of Biological Chemistry:2397-2411.
Gui, Ting; Gai, Zhibo (2015). Genome-wide profiling to analyze the effects of FXR activation on mouse renal proximal tubular cells. Genomics Data, 6:31-32.
Weiler, Stefan; Bellmann, Romuald; Kullak-Ublick, Gerd A (2015). 5-Oxoprolin (Pyroglutaminsäure) Azidose unter Paracetamol - Eine Differentialdiagnose der metabolischen Azidose mit erhöhter Anionenlücke. Therapeutische Umschau. Revue thérapeutique, 72(11-12):737-741.
Ruiz, Yasmin; Fuchs, Joan; Beuschel, Ralf; Tschopp, Markus; Goldblum, David (2015). Dangerous reef aquaristics: Palytoxin of a brown encrusting anemone causes toxic corneal reactions. Toxicon, 106:42-45.
Visentin, Michele; Stieger, Bruno; Merz, Michael; Kullak-Ublick, Gerd A (2015). Octreotide Inhibits the Bilirubin Carriers Organic Anion Transporting Polypeptides 1B1 and 1B3 and the Multidrug Resistance-Associated Protein 2. Journal of Pharmacology and Experimental Therapeutics, 355(2):145-151.
de Vallière, Cheryl; Vidal, Solange; Clay, Ieuan; Jurisic, Giorgia; Tcymbarevich, Irina; Lang, Silvia; Ludwig, Marie-Gabrielle; Okoniewski, Michal; Eloranta, Jyrki J; Kullak-Ublick, Gerd A; Wagner, Carsten A; Rogler, Gerhard; Seuwen, Klaus (2015). The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment. American Journal Of Physiology. Gastrointestinal And Liver Physiology, 309(6):475-490.
Welte, René; Eschertzhuber, Stephan; Weiler, Stefan; Leitner-Rupprich, Sandra; Aigner, Maria; Lass-Flörl, Cornelia; Stienecke, Eva; Bellmann-Weiler, Rosa; Joannidis, Michael; Bellmann, Romuald (2015). Biliary amphotericin B pharmacokinetics and pharmacodynamics in critically ill liver transplant recipients receiving treatment with amphotericin B lipid formulations. International Journal of Antimicrobial Agents, 46(3):325-331.
Gao, Bo; Vavricka, Stephan R; Meier, Peter J; Stieger, Bruno (2015). Differential cellular expression of organic anion transporting peptides OATP1A2 and OATP2B1 in the human retina and brain: implications for carrier-mediated transport of neuropeptides and neurosteriods in the CNS. Pflügers Archiv : European Journal of Physiology, 467(7):1481-1493.
Slijepcevic, Davor; Kaufman, Christina; Wichers, Catharina G K; Gilglioni, Eduardo H; Lempp, Florian A; Duijst, Suzanne; de Waart, Dirk R; Oude Elferink, Ronald P J; Mier, Walter; Stieger, Bruno; Beuers, Ulrich; Urban, Stephan; van de Graaf, Stan F J (2015). Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice. Hepatology, 62(1):207-219.
de Vallière, Cheryl; Wang, Yu; Eloranta, Jyrki J; Vidal, Solange; Clay, Ieuan; Spalinger, Marianne R; Tcymbarevich, Irina; Terhalle, Anne; Ludwig, Marie-Gabrielle; Suply, Thomas; Fried, Michael; Kullak-Ublick, Gerd A; Frey-Wagner, Isabelle; Scharl, Michael; Seuwen, Klaus; Wagner, Carsten A; Rogler, Gerhard (2015). G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation. Inflammatory Bowel Diseases, 21(6):1269-1281.
Ceschi, Alessandro; et al; Krähenbühl, Stephan; Taegtmeyer, Anne B (2015). Acute sirolimus overdose: a multicenter case series. PLoS ONE, 10(5):e01280331.
Bachour-El Azzi, Pamela; Sharanek, Ahmad; Burban, Audrey; Li, Ruoya; Le Guével, Rémy; Abdel-Razzak, Ziad; Stieger, Bruno; Guguen-Guillouzo, Christiane; Guillouzo, André (2015). Comparative localization and functional activity of the main hepatobiliary transporters in HepaRG cells and primary human hepatocytes. Toxicological Sciences, 145(1):157-168.
Sun, Shijie; Li, Minglong; Zhou, Jie; Gai, Zhibo; Shi, Haiyan; Zhao, Qing; Tian, Jun (2015). Cystatin C predicts diabetic retinopathy in Chinese patients with type 2 diabetes. International Journal of Diabetes in Developing Countries, 35(Suppl 3):398-404.
Feuerstacke, Christian. Role of Skeletal Muscle Transport Systems in Statin-Induced Myotoxicity. 2015, University of Zurich, Faculty of Science.
Gnädinger, Markus; Ceschi, Alessandro; Conen, Dieter; Herzig, Lilli; Puhan, Milo; Staehelin, Alfred; Zoller, Marco (2015). Medication incidents in primary care medicine: protocol of a study by the Swiss Federal Sentinel Reporting System. BMJ Open, 5(4):e007773.
Zhao, Rongbao; Visentin, Michele; Goldman, I David (2015). Determinants of the activities of antifolates delivered into cells by folate-receptor-mediated endocytosis. Cancer Chemotherapy and Pharmacology, 75(6):1163-1173.
Le Vee, Marc; Jouan, Elodie; Noel, Gregory; Stieger, Bruno; Fardel, Olivier (2015). Polarized location of SLC and ABC drug transporters in monolayer-cultured human hepatocytes. Toxicology in Vitro, 29(5):938-946.
Di Lorenzo, Chiara; Ceschi, Alessandro; Colombo, Francesca; Frigerio, Gianfranco; Bianchetti, Mario G; Lüde, Saskia; von Dechend, Margot; Valoti, Ermanno; Restani, Patrizia (2015). Identification and quantification of biomarkers to confirm the poisoning by Ginkgo biloba seeds in a 2-year-old boy. Toxicology Research, 4(4):922-930.
Ulrich, A; Weiler, S; Weller, M; Rordorf, T; Tarnutzer, A A (2015). Cetuximab induced aseptic meningitis. Journal of Clinical Neuroscience, 22(6):1061-1063.
Martos, Viktor; Hofer, Katharina E; Rauber-Lüthy, Christine; Schenk-Jaeger, Katharina M; Kupferschmidt, Hugo; Ceschi, Alessandro (2015). Acute toxicity profile of tolperisone in overdose: Observational poison centre-based study. Clinical Toxicology, 53(5):470-476.
Stieger, Bruno; Gao, Bo (2015). Drug transporters in the central nervous system. Clinical Pharmacokinetics, 54(3):225-242.
Brenner, Stefan; Riha, Juliane; Giessrigl, Benedikt; Thalhammer, Theresia; Grusch, Michael; Krupitza, Georg; Stieger, Bruno; Jäger, Walter (2015). The effect of organic anion-transporting polypeptides 1B1, 1B3 and 2B1 on the antitumor activity of flavopiridol in breast cancer cells. International Journal of Oncology, 46(1):324-332.
Di Lorenzo, Chiara; Ceschi, Alessandro; Kupferschmidt, Hugo; Lüde, Saskia; De Souza Nascimento, Elizabeth; Dos Santos, Ariana; Colombo, Francesca; Frigerio, Gianfranco; Nørby, Karin; Plumb, Jenny; Finglas, Paul; Restani, Patrizia (2015). Adverse Effects of Plant Food Supplements and Botanical Preparations: A Systematic Review with Critical Evaluation of Causality. British Journal of Clinical Pharmacology, 79(4):578-592.
Dessauvagie, A S. Akzidentelle Vergiftungen durch Ingestion umgefüllter, flüssiger Chemikalien: Retrospektive Analyse der Fälle des Tox Info Suisse 1997-2011. 2015, University of Zurich, Faculty of Medicine.
Sun, Dongfeng; Wang, Xiao; Gai, Zhibo; Song, Xiaoming; Jia, Xinyong; Tian, Hui (2015). Bile acids but not acidic acids induce Barrett's esophagus. International Journal of Clinical and Experimental Pathology, 8(2):1384-1392.
Weiler, Stefan; Merz, Michael; Kullak-Ublick, Gerd A (2015). Drug-induced liver injury: the dawn of biomarkers? F1000 Prime Reports, 7(34):online.
Degrandi, Colette; Winter, Andreas; Dullenkopf, Alexander; Reichert, Cornelia (2015). Fett für einmal gesund. Swiss Medical Forum, 15(11):260-262.
Hegedűs, Tamás; Chaubey, Pururawa Mayank; Várady, György; Szabó, Edit; Sarankó, Hajnalka; Hofstetter, Lia; Roschitzki, Bernd; Stieger, Bruno; Sarkadi, Balázs (2015). Inconsistencies in the red blood cell membrane proteome analysis: generation of a database for research and diagnostic applications. Database, 2015:online.
Weiler, S; Kullak-Ublick, G A; Jetter, A (2015). Klinisch relevante unerwünschte Arzneimittelinteraktionen: Tipps für die Praxis. Swiss Medical Forum, 15(7):152-156.
Dahmke, H; Kupferschmidt, H; Kullak-Ublick, G A; Weiler, S (2015). Nalmefen und Opioid-Entzugssyndrom: systematische Analyse der globalen Pharmacovigilance Datenbank. Praxis, 2015(104):1129-1134.
Koster, Markus; Schmidli, Markus; Hofer, Katharina E; Schmitter, Timo (2015). Nicht mehr als 1/16 eines Kaffeelöffels, sonst wird es gefährlich! Swiss Medical Forum, 15(12):282-284.
Chin, Siew Hung; Item, Flurin; Wueest, Stephan; Zhou, Zhou; Wiedemann, Michael S F; Gai, Zhibo; Schoenle, Eugen J; Kullak-Ublick, Gerd A; Al-Hasani, Hadi; Konrad, Daniel (2015). Opposing effects of reduced kidney mass on liver and skeletal muscle insulin sensitivity in obese mice. Diabetes, 64(4):1131-1141.
Schmitt, Johannes; Kong, Bo; Stieger, Bruno; Tschopp, Oliver; Schultze, Simon M; Rau, Monika; Weber, Achim; Muellhaupt, Beat; Guo, Grace L; Geier, Andreas (2015). Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal. Liver International, 35(4):1133-1144.
Le Vee, Marc; Jouan, Elodie; Stieger, Bruno; Lecureur, Valérie; Fardel, Olivier (2015). Regulation of human hepatic drug transporter activity and expression by diesel exhaust particle extract. PLoS ONE, 10(3):e0121232.
Weiler, S; Cornely, O A (2015). Systemische Mykosen. In: Herold, Gerd. Innere Medizin 2016. Köln: Herold Verlag, 388-390.
Schaffner, Carlos A; Mwinyi, Jessica; Gai, Zhibo; Thasler, Wolfgang E; Eloranta, Jyrki J; Kullak-Ublick, Gerd A (2015). The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes. Liver International, 35(4):1152-1161.
Reiber, Claudine; Senn, Oliver; Müller, Daniel; Kullak-Ublick, Gerd A; Corti, Natascia (2015). Therapeutic drug monitoring of daptomycin: a retrospective monocentric analysis. Therapeutic Drug Monitoring, 37(5):634-640.
Karlen, Sascha; Oertle, Marc; Weiler, Stefan; Schneemann, Markus; Eschmann, Emmanuel; Kullak-Ublick, Gerd-Achim; Blaser, Juerg (2015). Too frequent low-dose methotrexate prescriptions: multicentre quality control and quality assurance with pre- and post-analysis. Swiss Medical Weekly, 145:w14218.
Stieger, B; Kullak-Ublick, G A (2015). Transporters in the liver. In: Urban, L; Patel, V F; Vaz, R J. Antitargets and Drug Safety. KGaA, Weinheim: Wiley-VCH Verlag GmbH & Co., 159-171.
Stieger, Bruno; Unadkat, Jashvant D; Prasad, Bhagwat; Langer, Oliver; Gali, Hariprasad (2014). Role of (drug) transporters in imaging in health and disease. Drug Metabolism and Disposition, 42(12):2007-2015.
Mercier, Thomas; Tissot, Fréderic; Gardiol, Céline; Corti, Natascia; Wehrli, Stéphane; Guidi, Monia; Csajka, Chantal; Buclin, Thierry; Couet, William; Marchetti, Oscar; Decosterd, Laurent A (2014). High-throughput hydrophilic interaction chromatography coupled to tandem mass spectrometry for the optimized quantification of the anti-Gram-negatives antibiotic colistin A/B and its pro-drug colistimethate. Journal of Chromatography. A, 1369:52-63.
Kullak-Ublick, Gerd A; Merz, Michael; Griffel, Louis; Kaplowitz, Neil; Watkins, Paul B (2014). Liver safety assessment in special populations (hepatitis B, C, and oncology trials). Drug Safety, 37 Suppl:57-62.
Merz, Michael; Lee, Kwan R; Kullak-Ublick, Gerd A; Brueckner, Andreas; Watkins, Paul B (2014). Methodology to assess clinical liver safety data. Drug Safety, 37 Suppl:33-45.
Riha, Juliane; Brenner, Stefan; Böhmdorfer, Michaela; Giessrigl, Benedikt; Pignitter, Marc; Schueller, Katharina; Thalhammer, Theresia; Stieger, Bruno; Somoza, Veronika; Szekeres, Thomas; Jäger, Walter (2014). Resveratrol and its major sulfated conjugates are substrates of organic anion transporting polypeptides (OATPs): impact on growth of ZR-75-1 breast cancer cells. Molecular Nutrition & Food Research, 58(9):1830-1842.
Gai, Zhibo; Hiller, Christian; Chin, Siew Hung; Hofstetter, Lia; Stieger, Bruno; Konrad, Daniel; Kullak-Ublick, Gerd A (2014). Uninephrectomy augments the effects of high fat diet induced obesity on gene expression in mouse kidney. Biochimica et Biophysica Acta, 1842(9):1870-1878.
Ramelli, V; Ramelli, G P; Lava, S A G; Siegenthaler, G M; Bianchetti, M G; Ceschi, A (2014). Vitamin D status among children and adolescents on anticonvulsant drugs in Southern Switzerland. Swiss Medical Weekly, 144(144):w13996.
Weiler, Stefan; Gemperli, Armin; Collet, Tinh-Hai; Bauer, Douglas C; Zimmerli, Lukas; Cornuz, Jacques; Battegay, Edouard; Gaspoz, Jean-Michel; Kerr, Eve A; Aujesky, Drahomir; Rodondi, Nicolas (2014). Clinically relevant quality measures for risk factor control in primary care: a retrospective cohort study. BMC Health Services Research, 14(1):306.
Reichert, C; Reichert, P; Monnet-Tschudi, F; Kupferschmidt, H; Ceschi, A; Rauber-Lüthy, C (2014). Seizures after single-agent overdose with pharmaceutical drugs: analysis of cases reported to a poison center. Clinical Toxicology, 52(6):629-634.
Basler, Michelle; Jetter, Alexander; Fink, Daniel; Seifert, Burkhardt; Kullak-Ublick, Gerd A; Trojan, Andreas (2014). Urinary excretion of melatonin and association with breast cancer: meta-analysis and review of the literature. Breast Care, 9(3):182-187.
Mwinyi, Jessica; Vokinger, Kerstin Noëlle; Jetter, Alexander; Breitenstein, Urs; Hiller, Christian; Kullak-Ublick, Gerd A; Trojan, Andreas (2014). Impact of variable CYP genotypes on breast cancer relapse in patients undergoing adjuvant tamoxifen therapy. Cancer Chemotherapy and Pharmacology, 73(6):1181-1188.
Fuchs, Joan; von Dechend, Margot; Mordasini, Raffaella; Ceschi, Alessandro; Nentwig, Wolfgang (2014). A verified spider bite and a review of the literature confirm Indian ornamental tree spiders (Poecilotheria species) as underestimated theraphosids of medical importance. Toxicon, 77:73-77.
Ceschi, Alessandro; Gregoriano, Claudia; Rauber-Lüthy, Christine; Kupferschmidt, Hugo; Banner, Nicholas R; Krähenbühl, Stephan; Taegtmeyer, Anne B (2014). Acute mycophenolate overdose: case series and systematic literature analysis. Expert Opinion on Drug Safety, 13(5):525-534.
Gregoriano, Claudia; Ceschi, Alessandro; Rauber-Lüthy, Christine; Kupferschmidt, Hugo; Banner, Nicholas R; Krähenbühl, Stephan; Taegtmeyer, Anne B (2014). Acute thiopurine overdose: analysis of reports to a national poison centre 1995-2013. PLoS ONE, 9(1):e86390.
Hofer, K E; Degrandi, C; Müller, D M; Zürrer-Härdi, U; Wahl, S; Rauber-Lüthy, C; Ceschi, A (2014). Acute toxicity associated with the recreational use of the novel dissociative psychoactive substance methoxphenidine. Clinical Toxicology, 52(10):1288-1291.
Weiler, S; Corti, N (2014). Antibiotikatherapie: Wirkung und Resistenz. Medizinische Klinik : Intensivmedizin und Notfallmedizin, 109(3):167-174.
Stieger, Bruno; Kullak-Ublick, Gerd A (2014). Arzneimittel-Interaktionen auf der Ebene von Transportern des Hepatozyten. Pharmazeutische Medizin, 16(1):36-41.
Meli, Marianne; Rauber-Lüthy, Christine; Hoffmann-Walbeck, Petra; Reinecke, Hans-Jürgen; Prasa, Dagmar; Stedtler, Uwe; Färber, Elke; Genser, Dieter; Kupferschmidt, Hugo; Kullak-Ublick, Gerd A; Ceschi, Alessandro (2014). Atypical antipsychotic poisoning in young children: a multicentre analysis of poisons centres data. European Journal of Pediatrics, 173(6):743-750.
Meli, Marianne. Atypical antipsychotic poisoning in young children: a multicentre analysis of poisons centres data. 2014, University of Zurich, Faculty of Medicine.
Eloranta, J J; Stieger, B; Kullak-Ublick, G A (2014). Bile salt transporters. In: You, G; Morris, M E. Drug Transporters: Molecular Characterization and Role in Drug Disposition. Hoboken, New Jersey: Wiley Series in Drug Discovery and Development, John Wiley & Sons Inc.., 127-139.
Aellig, N; Krüger, B; Schwartz, T; Kullak-Ublick, G A; Schmid-Grendelmeier, P; Russmann, S (2014). Chlorhexidin-Allergie. Swiss Medical Forum, 14(15):321-322.
Gai, Zhibo; Chu, Lei; Hiller, Christian; Arsenijevic, Denis; Penno, Carlos A; Montani, Jean-Pierre; Odermatt, Alex; Kullak-Ublick, Gerd A (2014). Effect of chronic renal failure on the hepatic, intestinal, and renal expression of bile acid transporters. American Journal of Physiology : Renal Physiology, 306(1):F130-F137.
Schurter, David; Rauber-Lüthy, Christine; Jahns, Maximilian; Haberkern, Monika; Kupferschmidt, Hugo; Exadaktylos, Aristomenis; Eriksson, Urs; Ceschi, Alessandro (2014). Factors that trigger emergency physicians to contact a poison centre: findings from a Swiss study. Postgraduate medical journal, 90(1061):139-143.
Franzen, Daniel; Kohler, Malcolm; Degrandi, Colette; Kullak-Ublick, Gerd A; Ceschi, Alessandro (2014). Fire eater's lung: Retrospective analysis of 123 cases reported to a national poison center. Respiration, 87(2):98-104.
Töpf, Ana; Griffin, Helen R; Glen, Elise; Soemedi, Rachel; Brown, Danielle L; Hall, Darroch; Rahman, Thahira J; Eloranta, Jyrki J; Jüngst, Christoph; Stuart, A Graham; O'Sullivan, John; Keavney, Bernard D; Goodship, Judith A (2014). Functionally significant, rare transcription factor variants in tetralogy of Fallot. PLoS ONE, 9(8):e95453.
Gai, Zhibo (2014). Genome-wide profiling to analyze the effects of high fat diet induced obesity on renal gene expression in mouse with reduced renal mass. Genomics Data, 2:42-43.
Streit, Sven; da Costa, Bruno R; Bauer, Douglas C; Collet, Tinh-Hai; Weiler, Stefan; Zimmerli, Lukas; Frey, Peter; Cornuz, Jacques; Gaspoz, Jean-Michel; Battegay, Edouard; Kerr, Eve; Aujesky, Drahomir; Rodondi, Nicolas (2014). Multimorbidity and quality of preventive care in swiss university primary care cohorts. PLoS ONE, 9(4):e96142.
Stieger, Bruno; Hagenbuch, Bruno (2014). Organic anion-transporting polypeptides. Current Topics in Membranes, 73:205-32.
Russmann, Stefan; Niedrig, David F; Budmiger, Mathias; Schmidt, Caroline; Stieger, Bruno; Hürlimann, Sandra; Kullak-Ublick, Gerd A (2014). Rivaroxaban postmarketing risk of liver injury. Journal of Hepatology, 61(2):293-300.
Anwer, M Sawkat; Stieger, Bruno (2014). Sodium-dependent bile salt transporters of the SLC10A transporter family: more than solute transporters. Pflügers Archiv : European Journal of Physiology, 466(1):77-89.
Weiler, S (2014). Systemische Pilzinfektionen, sonstige systemische Mykosen, Therapie der systemischen Mykosen. In: Herold, Gerd. Herold - Innere Medizin 2014. Köln: Herold, Gerd, 386-389.
Pastor, Catherine M; Müllhaupt, Beat; Stieger, Bruno (2014). The role of organic anion transporters in diagnosing liver diseases by magnetic resonance imaging. Drug Metabolism and Disposition, 42(4):675-684.
Collet, Tinh-Hai; Bauer, Douglas C; Cappola, Anne R; Åsvold, Bjørn O; Weiler, Stefan; Vittinghoff, Eric; Gussekloo, Jacobijn; Bremner, Alexandra; den Elzen, Wendy P J; Maciel, Rui M B; Vanderpump, Mark P J; Cornuz, Jacques; Dörr, Marcus; Wallaschofski, Henri; Newman, Anne B; Sgarbi, José A; Razvi, Salman; Völzke, Henry; Walsh, John P; Aujesky, Drahomir; Rodondi, Nicolas (2014). Thyroid antibody status, subclinical hypothyroidism, and the risk of coronary heart disease: an individual participant data analysis. Journal of Clinical Endocrinology & Metabolism, 99(9):3353-3362.
Wlcek, Katrin; Hofstetter, Lia; Stieger, Bruno (2014). Transport of estradiol-17β-glucuronide, estrone-3-sulfate and taurocholate across the endoplasmic reticulum membrane: evidence for different transport systems. Biochemical Pharmacology, 88(1):106-118.
Weiler, S; Aellig, N; Fauchère, I; Jetter, A; Corti, N (2014). Treatment of gout in a renal transplant patient leading to severe thrombocytopenia. Journal of Clinical Pharmacy and Therapeutics, 39(5):571-572.
Dayal, Jasbani H S; Cole, Clare L; Pourreyron, Celine; Watt, Stephen A; Lim, Yok Zuan; Salas-Alanis, Julio C; Murrell, Dedee F; McGrath, John A; Stieger, Bruno; Jahoda, Colin; Leigh, Irene M; South, Andrew P (2014). Type VII collagen regulates expression of OATP1B3, promotes front-to-rear polarity and increases structural organisation in 3D spheroid cultures of RDEB tumour keratinocytes. Journal of Cell Science, 127(Pt 4):740-751.
Biason-Lauber, Anna; Böni-Schnetzler, Marianne; Hubbard, Basil P; Bouzakri, Karim; Brunner, Andrea; Cavelti-Weder, Claudia; Keller, Cornelia; Meyer-Böni, Monika; Meier, Daniel T; Brorsson, Caroline; Timper, Katharina; Leibowitz, Gil; Patrignani, Andrea; Bruggmann, Remy; Boily, Gino; Zulewski, Henryk; Geier, Andreas; Cermak, Jennifer M; Elliott, Peter; Ellis, James L; Westphal, Christoph; Knobel, Urs; Eloranta, Jyrki J; Kerr-Conte, Julie; Pattou, François; Konrad, Daniel; Matter, Christian M; Fontana, Adriano; Rogler, Gerhard; Schlapbach, Ralph; Regairaz, Camille; Carballido, José M; Glaser, Benjamin; McBurney, Michael W; Pociot, Flemming; Sinclair, David A; Donath, Marc Y (2013). Identification of a SIRT1 mutation in a family with type 1 Diabetes. Cell Metabolism, 17(3):448-455.
Ceschi, A; Rauber-Lüthy, C; Kupferschmidt, H (2013). Acute calcineurin inhibitor overdose: analysis of cases reported to a national poison center between 1995 and 2011. American Journal of Transplantation, 13(3):786-795.
Ceschi, A; Giardelli, G; Müller, D M; Elavumkudy, S; Manini, A F; Rauber-Lüthy, C; Hofer, K E (2013). Acute neurotoxicity associated with recreational use of methylmethaqualone confirmed by liquid chromatography tandem mass spectrometry. Clinical Toxicology, 51(1):54-57.
Biedermann, Luc; Mwinyi, Jessica; Scharl, Michael; Frei, Pascal; Zeitz, Jonas; Kullak-Ublick, Gerd A; Vavricka, Stephan R; Fried, Michael; Weber, Achim; Humpf, Hans-Ulrich; Peschke, Simone; Jetter, Alexander; Krammer, Gerhard; Rogler, Gerhard (2013). Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis - An open pilot study. Journal of Crohn's & colitis, 7(4):271-279.
Stieger, Bruno; Kullak-Ublick, Gerd A (2013). Bile salt Export Pump BSEP (ABCB11): Role in liver physiology and liver disease. In: Ishikawa, T; Kim, R B; König, J. Pharmacogenomics of Human Drug Transporters: Clinical Impacts. Hoboken, NJ, USA: Wiley-Blackwell, 295-309.
Ontsouka, Edgar Corneille; Huang, Xiao; Stieger, Bruno; Albrecht, Christiane (2013). Characteristics and functional relevance of apolipoprotein-A1 and cholesterol binding in mammary gland tissues and epithelial cells. PLoS ONE, 8(7):e70407.
Zorina, Olesya I; Haueis, Patrick; Greil, Waldemar; Grohmann, Renate; Kullak-Ublick, Gerd A; Russmann, Stefan (2013). Comparative performance of two drug interaction screening programmes analysing a cross-sectional prescription dataset of 84,625 psychiatric inpatients. Drug Safety, 36(4):247-258.
Le Vee, Marc; Jouan, Elodie; Stieger, Bruno; Fardel, Olivier (2013). Differential regulation of drug transporter expression by all-trans retinoic acid in hepatoma HepaRG cells and human hepatocytes. European Journal of Pharmaceutical Sciences, 48(4-5):767-774.
Hillgren, K M; Keppler, D; Zur, A A; Giacomini, K M; Stieger, B; Cass, C E; Zhang, L (2013). Emerging transporters of clinical importance: an update from the International Transporter Consortium. Clinical Pharmacology and Therapeutics, 94(1):52-63.
Preiswerk, B; Rudiger, A; Fehr, J; Corti, N (2013). Experience with daptomycin daily dosing in ICU patients undergoing continuous renal replacement therapy. Infection, 41(2):553-557.
Noel, Gregory; Le Vee, Marc; Moreau, Amélie; Stieger, Bruno; Parmentier, Yannick; Fardel, Olivier (2013). Functional expression and regulation of drug transporters in monolayer- and sandwich-cultured mouse hepatocytes. European Journal of Pharmaceutical Sciences, 49(1):39-50.
Weiss, T; Müller, D; Marti, I; Happold, C; Russmann, S (2013). Gamma-hydroxybutyrate (GHB) and topiramate-clinically relevant drug interaction suggested by a case of coma and increased plasma GHB concentration. European Journal of Clinical Pharmacology, 69(5):1193-1194.
Rauber-Lüthy, Christine; Hofer, Katharina E; Bodmer, Michael; Kullak-Ublick, Gerd A; Kupferschmidt, Hugo; Ceschi, Alessandro (2013). Gastric pharmacobezoars in quetiapine extended-release overdose: a case series. Clinical Toxicology, 51(10):937-940.
Nies, Anne T; Niemi, Mikko; Burk, Oliver; Winter, Stefan; Zanger, Ulrich M; Stieger, Bruno; Schwab, Matthias; Schaeffeler, Elke (2013). Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1. Genome Medicine, 5:1.
Wlcek, Katrin; Koller, Fabienne; Ferenci, Peter; Stieger, Bruno (2013). Hepatocellular organic anion-transporting polypeptides (OATPs) and multidrug resistance-associated protein 2 (MRP2) are inhibited by silibinin. Drug Metabolism and Disposition, 41(8):1522-1528.
Rau, Monika; Stickel, Felix; Russmann, Stefan; Manser, Christine N; Becker, Philip P; Weisskopf, Michael; Schmitt, Johannes; Dill, Michael T; Dufour, Jean-François; Moradpour, Darius; Semela, David; Müllhaupt, Beat; Geier, Andreas (2013). Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection. Journal of Hepatology, 58(4):669-675.
Brouwer, K L R; Keppler, D; Hoffmaster, K A; Bow, D A J; Cheng, Y; Lai, Y; Palm, J E; Stieger, B; Evers, R (2013). In vitro methods to support transporter evaluation in drug discovery and development. Clinical Pharmacology and Therapeutics, 94(1):95-112.
González-Carmona, Maria A; Quasdorff, Maria; Vogt, Annabelle; Tamke, Anja; Yildiz, Yildiz; Hoffmann, Per; Lehmann, Thomas; Bartenschlager, Ralf; Engels, Joachim W; Kullak-Ublick, Gerd A; Sauerbruch, Tilman; Caselmann, Wolfgang H (2013). Inhibition of hepatitis C virus RNA translation by antisense bile acid conjugated phosphorothioate modified oligodeoxynucleotides (ODN). Antiviral Research, 97(1):49-59.
Heinrich, Henriette; Kullak-Ublick, Gerd A; Krayenbühl, Pierre-Alexandre (2013). Leberlebendspende – primum nihil nocere? Praxis, 102(21):1277-1283; quiz 1284.
Curkovic, Ivanka; Rentsch, Katharina M; Frei, Pascal; Fried, Michael; Rogler, Gerhard; Kullak-Ublick, Gerd A; Jetter, Alexander (2013). Low allopurinol doses are sufficient to optimize azathioprine therapy in inflammatory bowel disease patients with inadequate thiopurine metabolite concentrations. European Journal of Clinical Pharmacology, 69(8):1521-1531.
Bloch-Teitelbaum, Alexandra; Lüde, Saskia; Rauber-Lüthy, Christine; Kupferschmidt, Hugo; Russmann, Stefan; Kullak-Ublick, Gerd A; Ceschi, Alessandro (2013). Medication wrong route administration: a poisons center-based study. Expert Opinion on Drug Safety, 12(2):145-152.
Jacomella, Vincenzo; Corti, Natascia; Husmann, Marc (2013). Novel anticoagulants in the therapy of peripheral arterial and coronary artery disease. Current Opinion in Pharmacology, 13(2):294-300.
Ljung, R; Auerswald, G; Benson, G; Jetter, A; Jiménez-Yuste, V; Lambert, T; Morfini, M; Remor, E; Sørensen, B; Salek, S Z (2013). Novel coagulation factor concentrates: issues relating to their clinical implementation and pharmacokinetic assessment for optimal prophylaxis in haemophilia patients. Haemophilia, 19(4):481-486.
Gutscher, Karen; Rauber-Lüthy, Christine; Haller, Marina; Braun, Michèle; Kupferschmidt, Hugo; Kullak-Ublick, Gerd A; Ceschi, Alessandro (2013). Patterns of toxicity and factors influencing severity in acute adult trimipramine poisoning. British Journal of Clinical Pharmacology, 75(1):227-235.
Kullak-Ublick, Gerd A (2013). Personalisierte Medizin: Fokus der Klinischen Pharmakologie. Pipette, 1:8-9.
Mwinyi, Jessica. Pharmacogenetics of nuclear receptors and drug transporters in inflammatory bowel disease and hepatic drug metabolism. 2013, University of Zurich, Faculty of Medicine.
Corti, Natascia; Rudiger, Alain; Chiesa, Alessandro; Marti, Isabelle; Jetter, Alexander; Rentsch, Katharina; Müller, Daniel; Béchir, Markus; Maggiorini, Marco (2013). Pharmacokinetics of daily daptomycin in critically ill patients undergoing continuous renal replacement therapy. Chemotherapy, 59(2):143-151.
Jetter, Alexander (2013). Pharmakodynamik und -kinetik: Wissenswertes zu den H1-Antihistaminika der 1. und 2. Generation. Hausarzt Praxis, 8(3):14-17.
Hoekstra, Lisette T; de Graaf, Wilmar; Nibourg, Geert A A; Heger, Michal; Bennink, Roelof J; Stieger, Bruno; van Gulik, Thomas M (2013). Physiological and biochemical basis of clinical liver function tests: a review. Annals of Surgery, 257(1):27-36.
Le Vee, Marc; Noel, Gregory; Jouan, Elodie; Stieger, Bruno; Fardel, Olivier (2013). Polarized expression of drug transporters in differentiated human hepatoma HepaRG cells. Toxicology in Vitro, 27(6):1979-1986.
Godoy, Patricio; Hewitt, Nicola J; et al; Kelm, Jens M; Kullak-Ublick, Gerd A; Messner, Simon; Mwinyi, Jessica (2013). Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Archives of Toxicology, 87(8):1315-1530.
Curkovic, Ivanka; Egbring, Marco; Kullak-Ublick, Gerd A (2013). Risks of inflammatory bowel disease treatment with glucocorticosteroids and aminosalicylates. Digestive Diseases, 31(3-4):368-373.
Stieger, Bruno; Kullak-Ublick, Gerd A (2013). Role of membrane transport in hepatotoxicity and pathogenesis of drug-induced cholestasis. In: Kaplowitz, N; DeLeve, L D. Drug-Induced Liver Disease. unknown: Elsevier, 123-133.
Monte, Andrew A; Ceschi, Alessandro; Bodmer, Michael (2013). Safety of non-therapeutic atomoxetine exposures - a national poison data system study. Human Psychopharmacology: Clinical and Experimental, 28(5):471-476.
Pavik, Ivana; Jaeger, Philippe; Ebner, Lena; Wagner, Carsten A; Petzold, Katja; Spichtig, Daniela; Poster, Diane; Wüthrich, Rudolf P; Russmann, Stefan; Serra, Andreas L (2013). Secreted Klotho and FGF23 in chronic kidney disease Stage 1 to 5: a sequence suggested from a cross-sectional study. Nephrology, Dialysis, Transplantation, 28(2):352-359.
Lucchini, Barbara; Simonetti, Giacomo D; Ceschi, Alessandro; Lava, Sebastiano A G; Faré, Pietro B; Bianchetti, Mario G (2013). Severe signs of hyponatremia secondary to desmopressin treatment for enuresis: a systematic review. Journal of Pediatric Urology, 9(6 Pt B):1049-1053.
Weiler, S; Offinger, A; Exadaktylos, A K (2013). Shaking head means "no". BMJ Case Reports, 2013:bcr2013200796.
Lepreux, Sébastien; Guyot, Christelle; Billet, Fabrice; Combe, Chantal; Balabaud, Charles; Bioulac-Sage, Paulette; Desmoulière, Alexis (2013). Smoothelin, a new marker to determine the origin of liver fibrogenic cells. World Journal of Gastroenterology, 19(48):9343-9350.
De Bruyn, Tom; van Westen, Gerard J P; Ijzerman, Adriaan P; Stieger, Bruno; de Witte, Peter; Augustijns, Patrick F; Annaert, Pieter P (2013). Structure-based identification of OATP1B1/3 inhibitors. Molecular Pharmacology, 83(6):1257-1267.
Gnädinger, M; Nentwig, W; Fuchs, J; Ceschic, A (2013). Swiss prospective study on spider bites. Swiss Medical Weekly, 143:w13877.
Hagenbuch, Bruno; Stieger, Bruno (2013). The SLCO (former SLC21) superfamily of transporters. Molecular Aspects of Medicine, 34(2-3):396-412.
Jetter, Alexander; Fuhr, Uwe (2013). The cocktail approach and its utility in drug-drug interaction assessments for therapeutic proteins. In: Zhou, Honghui. Drug-Drug Interaction Assessments for Therapeutic Proteins. Hoboken: John Wiley & Sons, 111-118.
Claro da Silva, Tatiana; Polli, James E; Swaan, Peter W (2013). The solute carrier family 10 (SLC10): beyond bile acid transport. Molecular Aspects of Medicine, 34(2-3):252-269.
Curkovic, Ivanka; Egbring, Marco; Kullak-Ublick, Gerd A (2013). Thrombozytenaggregationshemmer: Was sind die Risiken? Praxis, 102(20):1243-1250.
Jüttner, Moritz. Transcriptional regulation of intestinally amd hepatically expressed membrane transporter genes. 2013, University of Zurich, Faculty of Science.
Russmann, S; Kullak-Ublick, G A (2012). Beurteilung und Meldung medikamentöser Leberschäden. Vigilance-News, (10):9-14.
Russmann, Stefan; Kullak-Ublick, Gerd Achim (2012). Drug-induced liver injury (DILI). Apple App store for iOS (iPhone / iPad): European Association for the Study of the Liver (EASL).
Russmann, S; Kullak-Ublick, G A (2012). Arzneimittelsicherheit. In: Kullak-Ublick, G A; Siepmann, T; Kirch, W. Arzneimitteltherapie: Wirksamkeit - Sicherheit - Praktische Anwendung. Stuttgart: Thieme, 27-31.
Arzneimitteltherapie: Wirksamkeit - Sicherheit - Praktische Anwendung. Edited by: Kullak-Ublick, G A; Siepmann, T; Kirch, W (2012). Stuttgart: Thieme.
Achermann, Y; Frauenfelder, T; Obrist, S; Zaugg, K; Corti, N; Günthard, H F (2012). A rare but severe pulmonary side effect of cetuximab in two patients. BMJ Case Reports:5 pages.
Corti, N; Taegtmeyer, A B (2012). Alle Medikamente zum Frühstück? - Einfluss der Nahrung auf die Medikamentenwirkung. Praxis, 101(13):849-55.
Egert, Aurélie; Peters, Shaun; Guyot, Christelle; Stieger, Bruno; Keller, Felix (2012). An Arabidopsis T-DNA insertion mutant for galactokinase (AtGALK, At3g06580) hyperaccumulates free galactose and is insensitive to exogenous galactose. Plant & Cell Physiology, 53(5):921-929.
Russmann, S (2012). Arzneimittelsicherheit in klinischen Studien. In: Kullak-Ublick, G A; Siepmann, T; Kirch, W. Arzneimitteltherapie: Wirksamkeit - Sicherheit - Praktische Anwendung. Stuttgart: Thieme, 35-38.
Müller, E A; Krattinger, R (2012). Arzneitherapie gastrointestinaler Erkrankungen. In: Kullak-Ublick, G A; Siepmann, T; Kirch, W. Arzneimitteltherapie: Wirksamkeit - Sicherheit - Praktische Anwendung. Stuttgart: Thieme, 104-123.
Attinkara, Ragam; Mwinyi, Jessica; Truninger, Kaspar; Regula, Jaroslaw; Gaj, Pawel; Rogler, Gerhard; Kullak-Ublick, Gerd A; Eloranta, Jyrki J (2012). Association of genetic variation in the NR1H4 gene, encoding the nuclear bile acid receptor FXR, with inflammatory bowel disease. BMC Research Notes, 5:461.
Schumacher, Anette; Jacomella, Vincenzo; Stüssi, Georg; Amann-Vesti, Beatrice; Corti, Natascia; Marc Husmann, And (2012). Castleman's disease and arterial thrombosis: result of excessively elevated interleukin-6 plasma level? Vasa, 41(2):145-148.
Taegtmeyer, A B; Kullak-Ublick, G A; Widmer, N; Falk, V; Jetter, A (2012). Clinical Usefulness of Electronic Drug-Drug Interaction Checking in the Care of Cardiovascular Surgery Inpatients. Cardiology, 123(4):219-222.
Egbring, M; Russmann, S; Kullak-Ublick, G A (2012). Clinical decision support systems. In: Kullak-Ublick, G A; Siepmann, T; Kirch, W. Arzneimitteltherapie: Wirksamkeit - Sicherheit - Praktische Anwendung. Stuttgart: Thieme, 49-52.
Zorina, O I; Haueis, P; Semmler, A; Marti, I; Gonzenbach, R R; Guzek, M; Kullak-Ublick, G A; Weller, M; Russmann, S (2012). Comparative evaluation of the drug interaction screening programs MediQ and ID PHARMA CHECK in neurological inpatients. Pharmacoepidemiology and Drug Safety, 21(8):872-880.
Fritz, Daniela; Ceschi, Alessandro; Curkovic, Ivanka; Huber, Martin; Egbring, Marco; Kullak-Ublick, Gerd A; Russmann, Stefan (2012). Comparative evaluation of three clinical decision support systems: prospective screening for medication errors in 100 medical inpatients. European Journal of Clinical Pharmacology, 68(8):1209-1219.
Fritz, Daniela. Comparative evaluation of three clinical decision support systems: prospective screening for medication errors in one hundred medical inpatients. 2012, University of Zurich, Faculty of Medicine.
Schmitt, Johannes; Roderfeld, Martin; Sabrane, Karim; Zhang, Pan; Tian, Yinghua; Mertens, Joachim C; Frei, Pascal; Stieger, Bruno; Weber, Achim; Müllhaupt, Beat; Roeb, Elke; Geier, Andreas (2012). Complement factor C5 deficiency significantly delays the progression of biliary fibrosis in bile duct-ligated mice. Biochemical and Biophysical Research Communications (BBRC), 418(3):445-450.
Haueis, P; Russmann, S; Zorina, O I; Grohmann, R; Kullak-Ublick, G A; Jaquenoud Sirot, E; Russmann, H (2012). Coprescription of levodopa with antipsychotics in a population of 84 596 psychiatric inpatients from 1994 to 2008. Pharmacopsychiatry, 45(04):127-132.
Scharl, M; Mwinyi, J; Fischbeck, A; Leucht, K; Eloranta, J J; Arikkat, J; Pesch, T; Kellermeier, S; Mair, A; Kullak-Ublick, G A; Truninger, K; Noreen, F; Regula, J; Gaj, P; Pittet, V; Mueller, C; Hofmann, C; Fried, M; McCole, D F; Rogler, G (2012). Crohn's disease-associated polymorphism within the PTPN2 gene affects muramyl-dipeptide-induced cytokine secretion and autophagy. Inflammatory Bowel Diseases, 18(5):900-912.
Hammann, F; Hruz, P; Kullak-Ublick, G A; Vavricka, S R; Beglinger, C; Drewe, J; Gutmann, H (2012). Determination of the Single Nucleotide Polymorphisms C3435 and G2677T in MDR1 and C421A in BCRP in blood samples of patients with inflammatory bowel disease and healthy controls in the swiss population. Metabolomics, 2:104.
Huster, Dominik; Kühne, Angelika; Bhattacharjee, Ashima; Raines, Lily; Jantsch, Vanessa; Noe, Johannes; Schirrmeister, Wiebke; Sommerer, Ines; Sabri, Osama; Berr, Frieder; Mössner, Joachim; Stieger, Bruno; Caca, Karel; Lutsenko, Svetlana (2012). Diverse Functional Properties of Wilson Disease ATP7B Variants. Gastroenterology, 142(4):947-956.e5.
Taegtmeyer, A B; Curkovic, I; Corti, N; Rosen, C; Egbring, M; Russmann, S; Gantenbein, A R; Weller, M; Kullak-Ublick, G A (2012). Drug-related problems and factors influencing acceptance of clinical pharmacologists` alerts in a large cohort of neurology inpatients. Swiss Medical Weekly, 142:w13615.
Many, Natalie; Stickel, Felix; Schmitt, Johannes; Stieger, Bruno; Soyka, Michael; Frei, Pascal; Götze, Oliver; Müllhaupt, Beat; Geier, Andreas (2012). Genetic variations in bile acid homeostasis are not overrepresented in alcoholic cirrhosis compared to patients with heavy alcohol abuse and absent liver disease. Mutagenesis, 27(5):567-572.
Dahlqvist, M; Venzin, R; König, S; Faber, K; Weinmann, W; Terbeck, S; Ceschi, A; Dünser, M W (2012). Haemodialysis in Taxus Baccata poisoning: a case report. QJM, 105(4):359-361.
Trdan Lušin, Tina; Mrhar, Aleš; Stieger, Bruno; Kullak-Ublick, Gerd A; Marc, Janja; Ostanek, Barbara; Zavratnik, Andrej; Kristl, Albin; Berginc, Katja; Delić, Katja; Trontelj, Jurij (2012). Influence of hepatic and intestinal efflux transporters and their genetic variants on the pharmacokinetics and pharmacodynamics of raloxifene in osteoporosis treatment. Translational Research, 160(4):298-308.
Corti, N (2012). Intensivmedizinische Arzneitherapie. In: Kullak-Ublick, G A; Siepmann, T; Kirch, W. Arzneimitteltherapie: Wirksamkeit - Sicherheit - Praktische Anwendung. Stuttgart: Thieme, 359-371.
Frei, Pascal; Minder, Elisabeth I; Corti, Natascia; Muellhaupt, Beat; Geier, Andreas; Adams, Heiner; Dutertre, Jean-Paul; Rudiger, Alain; Dutkowski, Philipp; Maggiorini, Marco; Ganter, Christoph C (2012). Liver transplantation because of acute liver failure due to heme arginate overdose in a patient with acute intermittent porphyria. Case Reports in Gastroenterology, 6(1):190-196.
Haeberle, Anne; Greil, Waldemar; Russmann, Stefan; Grohmann, Renate (2012). Mono- and combination drug therapies in hospitalized patients with bipolar depression. Data from the European drug surveillance program AMSP. BMC Psychiatry, 12:153.
Schenk-Jaeger, Katharina M; Rauber-Lüthy, Christine; Bodmer, Michael; Kupferschmidt, Hugo; Kullak-Ublick, Gerd A; Ceschi, Alessandro (2012). Mushroom poisoning: a study on circumstances of exposure and patterns of toxicity. European Journal of Internal Medicine, 23(4):e85-91.
Schenk-Jaeger, Katharina M. Mushroom poisoning: circumstances of exposure and patterns of toxicity. 2012, University of Zurich, Faculty of Medicine.
Kupferschmidt, Hugo (2012). Neue Drogen. Praxis, 101:565-570.
Trdan Lušin, Tina; Stieger, Bruno; Marc, Janja; Mrhar, Aleš; Trontelj, Jurij; Zavratnik, Andrej; Ostanek, Barbara (2012). Organic anion transporting polypeptides OATP1B1 and OATP1B3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifene. Journal of Translational Medicine, 10:76.
Gutscher Claude, Karen. Patterns of toxicity and factors influencing severity in acute adult trimipramine poisoning. 2012, University of Zurich, Faculty of Medicine.
Greil, W; Häberle, A; Haueis, P; Grohmann, R; Russmann, S (2012). Pharmacotherapeutic trends in 2231 psychiatric inpatients with bipolar depression from the International AMSP Project between 1994 and 2009. Journal of Affective Disorders, 136(3):534-542.
Russmann, S (2012). Pharmakoepidemiologie. In: Kullak-Ublick, G A; Siepmann, T; Kirch, W. Arzneimitteltherapie: Wirksamkeit - Sicherheit - Praktische Anwendung. Stuttgart: Thieme, 42-48.
Taegtmeyer, A B; Ceschi, A; Kullak-Ublick, G A; Jetter, A (2012). Pharmakogenetik in der Praxis: warum, wie, wann? - Teil 1. Swiss Medical Forum, 12(42):808-811.
Taegtmeyer, A B; Ceschi, A; Kullak-Ublick, G A; Jetter, A (2012). Pharmakogenetik in der Praxis: warum, wie, wann? - Teil 2. Swiss Medical Forum, 12(42):824-826.
Sift Carter, R; Russmann, S; Stoller, R (2012). Pharmakovigilanz. In: Kullak-Ublick, G A; Siepmann, T; Kirch, W. Arzneimitteltherapie: Wirksamkeit - Sicherheit - Praktische Anwendung. Stuttgart: Thieme, 38-41.
Egbring, M (2012). Pharmakoökonomie. In: Kullak-Ublick, G A; Siepmann, T; Kirch, W. Arzneimitteltherapie: Wirksamkeit - Sicherheit - Praktische Anwendung. Stuttgart: Thieme, 23-26.
Goltz, Lisa; Kullak-Ublick, Gerd A; Kirch, Wilhelm (2012). Potentially inappropriate prescribing for elderly outpatients in Germany: a retrospective claims data analysis. International journal of clinical pharmacology and therapeutics, 50(3):185-194.
Ma, Liang. Regulation of intestinal bile acid transporter genes by the transcription factors CDX1 and CDX2. 2012, University of Zurich, Faculty of Science.
Ma, L; Jüttner, M; Kullak-Ublick, G A; Eloranta, J J (2012). Regulation of the gene encoding the intestinal bile acid transporter ASBT by the caudal-type homeobox proteins CDX1 and CDX2. American Journal of Physiology. Gastrointestinal and Liver Physiology, 302(1):G123-33.
Russmann, S (2012). Risiko von Arzneimittelinteraktionen - Therapie optimieren, Interaktionen vermeiden. Medical Tribune, (10):25-26.
Taegtmeyer, Anne B; Leuppi, Jörg D; Kullak-Ublick, Gerd A (2012). Roflumilast--a phosphodiesterase-4 inhibitor licensed for add-on therapy in severe COPD. Swiss Medical Weekly, 142:w13628.
Curkovic, I; Kullak-Ublick, G A (2012). Schmerztherapie und Lokalanästhetika. In: Kullak-Ublick, G A; Siepmann, T; Kirch, W. Arzneimitteltherapie: Wirksamkeit - Sicherheit - Praktische Anwendung. Stuttgart: Thieme, 228-246.
Jang, Jae-Hwi; Rickenbacher, Andreas; Humar, Bostjan; Weber, Achim; Raptis, Dimitri Aristotle; Lehmann, Kuno; Stieger, Bruno; Moritz, Wolfgang; Soll, Christopher; Georgiev, Panco; Fischer, David; Laczko, Endre; Graf, Rolf; Clavien, Pierre-Alain (2012). Serotonin protects mouse liver from cholestatic injury by decreasing bile salt pool after bile duct ligation. Hepatology, 56(1):209-218.
Eloranta, Jyrki J; Hiller, Christian; Juttner, Moritz; Kullak-Ublick, Gerd A (2012). The SLCO1A2 Gene, Encoding the Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2), is Transactivated by the Vitamin D Receptor (VDR). Molecular Pharmacology, 82(1):37-46.
Stieger, B; Heger, M; de Graaf, W; Paumgartner, G; van Gulik, T (2012). The emerging role of transport systems in liver function tests. European Journal of Pharmacology, 675(1-3):1-5.
Mwinyi, Jessica; Grete-Wenger, Christa; Eloranta, Jyrki J; Kullak-Ublick, Gerd A (2012). The impact of PPARγ genetic variants on IBD susceptibility and IBD disease course. PPAR Research, 2012:349469.
Sift Carter, R; Stoller, R; Russmann, S (2012). Unerwünschte Arzneimittelwirkungen. In: Kullak-Ublick, G A; Siepmann, T; Kirch, W. Arzneimitteltherapie: Wirksamkeit - Sicherheit - Praktische Anwendung. Stuttgart: Thieme, 32-35.
Far, Elmira; Curkovic, Ivanka; Byrne, Kelly; Roos, Malgorzata; Egloff, Isabelle; Dietrich, Michael; Kirch, Wilhelm; Kullak-Ublick, Gerd A; Egbring, Marco (2012). Validation of a transparent decision model to rate drug interactions. BMC Pharmacology & Toxicology, 13:7.
Corti, Natascia; Taegtmeyer, Anne; Curkovic, Ivanka (2012). Wechselwirkung von Medikamenten mit der Grunderkrankung - Wenn Medikamente Krankheiten verschlechtern. Praxis, 101:363-370.
Iwata, R; Baur, K; Stieger, B; Mertens, J C; Daly, A K; Frei, P; Braun, J; Vergopoulos, A; Stickel, F; Sabrane, K; Martin, I V; Schmitt, J; Goetze, O; Day, C P; Müllhaupt, B; Geier, A (2011). A common polymorphism in the ABCB11 gene is associated with advanced fibrosis in hepatitis C but not in non-alcoholic fatty liver disease. Clinical Science, 120(7):287-296.
Ceschi, A; Von Dechend, M; Krause, M; Kengelbacher, M; Stuerer, A (2011). Acute laryngotracheitis after accidental aspiration of clindamycin. QJM, 104(7):609-611.
Fuchs, J. Acute plant poisoning: Analysis of clinical features and circumstances of exposure. 2011, University of Zurich, Faculty of Medicine.
Fuchs, J; Rauber-Lüthy, C; Kupferschmidt, H; Kupper, J; Kullak-Ublick, G A; Ceschi, A (2011). Acute plant poisoning: analysis of clinical features and circumstances of exposure. Clinical Toxicology, 49(7):671-680.
Wagner, C C; Langer, O (2011). Approaches using molecular imaging technology - use of PET in clinical microdose studies. Advanced Drug Delivery Reviews, 63(7):539-546.
Eloranta, J J; Wenger, C; Mwinyi, J; Hiller, C; Gubler, C; Vavricka, S R; Fried, M; Kullak-Ublick, G A (2011). Association of a common vitamin D-binding protein polymorphism with inflammatory bowel disease. Pharmacogenetics and Genomics, 21(9):559-564.
Jetter, A. Beeinflussung und Quantifizierung der Aktivitäten arzneistoffmetabolisierender Enzyme bei Gesunden und Kranken. 2011, University of Zurich, Faculty of Medicine.
Wyen, C; Hendra, H; Siccardi, M; Platten, M; Jaeger, H; Harrer, T; Esser, S; Bogner, J R; Brockmeyer, N H; Bieniek, B; Rockstroh, J; Hoffmann, C; Stoehr, A; Michalik, C; Dlugay, V; Jetter, A; Knechten, H; Klinker, H; Skaletz-Rorowski, A; Fätkenheuer, G; Egan, D; Back, D J; Owen, A (2011). Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens. Journal of Antimicrobial Chemotherapy, 66(9):2092-2098.
Vavricka, B M P; Baumberger, P; Russmann, S; Kullak-Ublick, G A (2011). Diagnosis of melanoma under concomitant natalizumab therapy. Multiple Sclerosis, 17(2):255-256.
Taegtmeyer, Anne B; Breen, Jane B; Smith, John; Rogers, Paula; Kullak-Ublick, Gerd A; Yacoub, Magdi H; Banner, Nicholas R; Barton, Paul J R (2011). Effect of ABCB1 genotype on pre- and post-cardiac transplantation plasma lipid concentrations. Journal of Cardiovascular Translational Research, 4(3):304-312.
Taegtmeyer, A B; Müller, V; Kovari, H; Kullak-Ublick, G A; Corti, N (2011). Effect of continuous venovenous hemodiafiltration on darunavir and raltegravir exposure after administration via a gastroduodenal tube. AIDS, 25(10):1339-1341.
Tomalik-Scharte, D; Fuhr, U; Hellmich, M; Frank, D; Doroshyenko, O; Jetter, A; Stingl, J C (2011). Effect of the CYP2C8 genotype on the pharmacokinetics and pharmacodynamics of repaglinide. Drug Metabolism and Disposition, 39(5):927-932.
Taegtmeyer, A B; Curkovic, I; Rufibach, K; Corti, N; Battegay, E; Kullak-Ublick, G A (2011). Electronic prescribing increases uptake of clinical pharmacologists' recommendations in the hospital setting. British Journal of Clinical Pharmacology, 72(6):958-964.
Yilmaz, Z. Escitalopram causes fewer seizures in human overdose than citalopram. 2011, University of Zurich, Faculty of Medicine.
Guzek, M. Evaluation of drug interactions and dosing in 484 neurological inpatients using clinical decision support software and an extended operational interaction classification system (ZHIAS). 2011, University of Zurich, Faculty of Medicine.
Guzek, M; Zorina, O I; Semmler, A; Gonzenbach, R R; Huber, M; Kullak-Ublick, G A; Weller, M; Russmann, S (2011). Evaluation of drug interactions and dosing in 484 neurological inpatients using clinical decision support software and an extended operational interaction classification system (Zurich Interaction System). Pharmacoepidemiology and Drug Safety, 20(9):930-938.
Haueis, P; Greil, W; Huber, M; Grohmann, R; Kullak-Ublick, G A; Russmann, S (2011). Evaluation of drug interactions in a large sample of psychiatric inpatients: A data interface for mass analysis with clinical decision support software. Clinical Pharmacology and Therapeutics, 90(4):588-596.
Frölich, T; Zorina, O; Fontana, A O; Kullak-Ublick, G A; Vollenweider, A; Russmann, S (2011). Evaluation of medication safety in the discharge medication of 509 surgical inpatients using electronic prescription support software and an extended operational interaction classification. European Journal of Clinical Pharmacology, 67(12):1273-1282.
Frölich, T B. Evaluation of medication safety in the discharge medication of 509 surgical inpatients using electronic prescription support software and an extended operational interaction classification. 2011, University of Zurich, Faculty of Medicine.
Svoboda, M; Wlcek, K; Taferner, B; Hering, S; Stieger, B; Tong, D; Zeillinger, R; Thalhammer, T; Jäger, W (2011). Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport. Biomedicine & pharmacotherapy, 65(6):417-426.
Gonzenbach, R R; Taegtmeyer, A B; Luft, A; Russmann, S (2011). Fluoxetine and motor recovery after ischaemic stroke. Lancet Neurology, 10(6):499-500.
Stieger, B; Geier, A (2011). Genetic variations of bile salt transporters as predisposing factors for drug-induced cholestasis, intrahepatic cholestasis of pregnancy and therapeutic response of viral hepatitis. Expert Opinion on Drug Metabolism & Toxicology, 7(4):411-425.
Toniolo, M; Ceschi, A; Meli, M; Lohri, A; Favre, G (2011). Haemolytic anaemia and abdominal pain - a cause not to be missed. British Journal of Clinical Pharmacology, 72(1):168-169.
Millet, P; Moulin, M; Stieger, B; Daali, Y; Pastor, C M (2011). How organic anions accumulate in hepatocytes lacking mrp2: evidence in rat liver. Journal of Pharmacology and Experimental Therapeutics, 336(3):624-632.
Guyot, C; Stieger, B (2011). Interaction of bile salts with rat canalicular membrane vesicles: Evidence for bile salt resistant microdomains. Journal of Hepatology, 55(6):1368-1376.
Toniolo, M; Jetter, A (2011). Methotrexat und Cotrimoxazol bei rheumatologischen Patienten. Rheuma Schweiz, 3(5):47-49.
Grattagliano, I; Russmann, S; Diogo, C V; Bonfrate, L; Oliveira, P J; Wang, D Q H; Portincasa, P (2011). Mitochondria in chronic liver disease. Current Drug Targets, 12(6):879-893.
Hofer, K E; Trachsel, C; Rauber-Lüthy, C; Kupferschmidt, H; Kullak-Ublick, G A; Ceschi, A (2011). Moderate toxic effects following acute zonisamide overdose. Epilepsy & Behavior, 21(1):91-93.
Opitz, I; Erne, B V; Demirbas, S; Jetter, A; Seifert, Burkhardt; Stahel, R; Weder, W (2011). Optimized intrapleural cisplatin chemotherapy with a fibrin carrier after extrapleural pneumonectomy: a preclinical study. Journal of Thoracic and Cardiovascular Surgery, 141(1):65-71.
Ceschi, A; Hofer, K E; Rauber-Lüthy, C; Kupferschmidt, H (2011). Paracetamol orodispersible tablets: a risk for severe poisoning in children? European Journal of Clinical Pharmacology, 67(1):97-99.
Stieger, B; Meier, P J (2011). Pharmacogenetics of drug transporters in the enterohepatic circulation. Pharmacogenomics, 12(5):611-631.
Le Vee, M; Jouan, E; Stieger, B; Lecureur, V; Fardel, O (2011). Regulation of drug transporter expression by oncostatin M in human hepatocytes. Biochemical Pharmacology, 82(3):304-311.
Stieger, B (2011). Regulation of the expression of the hepatocellular sulfate-oxalate exchanger SAT-1 (SLC26A1) by glyoxylate: A metabolic link between liver and kidney? Journal of Hepatology, 54(3):406-407.
De Bruyn, T; Fattah, S; Stieger, B; Augustijns, P; Annaert, P (2011). Sodium fluorescein is a probe substrate for hepatic drug transport mediated by OATP1B1 and OATP1B3. Journal of Pharmaceutical Sciences, 100(11):5018-5030.
Stieger, B (2011). The Role of the Sodium-Taurocholate Cotransporting Polypeptide (NTCP) and of the Bile Salt Export Pump (BSEP) in Physiology and Pathophysiology of Bile Formation. Handbook of Experimental Pharmacology, (201):205-259.
Stieger, B; Beuers, U (2011). The canalicular bile salt export pump BSEP (ABCB11) as a potential therapeutic target. Current Drug Targets, 12(5):661-670.
Chan, S Y; Martín-Santos, A; Loubière, L S; González, A M; Stieger, B; Logan, A; McCabe, C J; Franklyn, J A; Kilby, M D (2011). The expression of thyroid hormone transporters in the human fetal cerebral cortex during early development and in N-Tera-2 neurodifferentiation. Journal of Physiology, 589(Pt 11):2827-2845.
Iwata, R; Stieger, B; Mertens, J C; Müller, T; Baur, K; Frei, P; Braun, J; Vergopoulos, A; Martin, I V; Schmitt, J; Goetze, O; Bibert, S; Bochud, P Y; Müllhaupt, B; Berg, T; Geier, A (2011). The role of bile acid retention and a common polymorphism in the ABCB11 gene as host factors affecting antiviral treatment response in chronic hepatitis C. Journal of Viral Hepatitis, 18(11):768-778.
de Graaf, W; Häusler, S; Heger, M; van Ginhoven, T M; van Cappellen, G; Bennink, R J; Kullak-Ublick, G A; Hesselmann, R; van Gulik, T M; Stieger, B (2011). Transporters involved in the hepatic uptake of (99m)Tc-mebrofenin and indocyanine green. Journal of Hepatology, 54(4):738-745.
Egloff, I M. Visualisierung und Klassifikation von Arzneimittelinteraktionen. 2011, University of Zurich, Faculty of Medicine.
Mwinyi, J; Wenger, C; Eloranta, J J; Kullak-Ublick, G A (2010). Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients. World Journal of Gastroenterology, 16(31):3888-3896.
de Waart, D R; Häusler, S; Vlaming, M L H; Kunne, C; Hänggi, E; Gruss, H-J; Oude Elferink, R P J; Stieger, B (2010). Hepatic transport mechanisms of cholyl-L-lysyl-fluorescein. Journal of Pharmacology and Experimental Therapeutics, 334(1):78-86.
Schürch, R; Todesco, L; Novakova, K; Mevissen, M; Stieger, B; Krähenbühl, S (2010). The plasma carnitine concentration regulates renal OCTN2 expression and carnitine transport in rats. European Journal of Pharmacology, 635(1-3):171-176.
Russmann, S; Curkovic, I; Huber, M (2010). Risiken und Nebenwirkungen durch Non Compliance. Therapeutische Umschau, 67(6):303-307.
Davit-Spraul, A; Fabre, M; Branchereau, S; Baussan, C; Gonzales, E; Stieger, B; Bernard, O; Jacquemin, E (2010). ATP8B1 and ABCB11 analysis in 62 children with normal gamma-glutamyl transferase progressive familial intrahepatic cholestasis (PFIC): phenotypic differences between PFIC1 and PFIC2 and natural history. Hepatology, 51(5):1645-1655.
Pauli-Magnus, Christiane; Meier, Peter J; Stieger, Bruno (2010). Genetic determinants of drug-induced cholestasis and intrahepatic cholestasis of pregnancy. Seminars in Liver Disease, 30(2):147-159.
Egbring, M; Kullak-Ublick, G A; Russmann, S (2010). Phynx: an open source software solution supporting data management and web-based patient-level data review for drug safety studies in the general practice research database and other health care databases. Pharmacoepidemiology and Drug Safety, 19(1):38-44.
Ceschi, A; Curkovic, I; Kirchheiner, J; Kullak-Ublick, G; Jetter, A (2010). Arzneimittelinteraktionen mit antiretroviralen Medikamenten. Der Internist, 51(1):94-99.
Abduljalil, K; Frank, D; Gaedigk, A; Klaassen, T; Tomalik-Scharte, D; Jetter, A; Jaehde, U; Kirchheiner, J; Fuhr, U (2010). Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan. Clinical Pharmacology and Therapeutics, 88(5):643-651.
Martin, Ina V; Schmitt, Johannes; Minkenberg, Alexander; Mertens, Joachim C; Stieger, Bruno; Müllhaupt, Beat; Geier, Andreas (2010). Bile acid retention and activation of endogenous hepatic farnesoid-X-receptor in the pathogenesis of fatty liver disease in ob/ob-mice. Biological Chemistry, 391(12):1441-1449.
Jetter, A; Fätkenheuer, G; Frank, D; Klaassen, T; Seeringer, A; Doroshyenko, O; Kirchheiner, J; Hein, W; Schömig, E; Fuhr, U; Wyen, C (2010). Do activities of cytochrome P450 (CYP)3A, CYP2D6 and P-glycoprotein differ between healthy volunteers and HIV-infected patients? Antiviral Therapy, 15(7):975-983.
Peters, Rowayda; Wolf, Monika J; van den Broek, Maries; Nuvolone, Mario; Dannenmann, Stefanie; Stieger, Bruno; Rapold, Reto; Konrad, Daniel; Rubin, Arnold; Bertino, Joseph R; Aguzzi, Adriano; Heikenwalder, Mathias; Knuth, Alexander K (2010). Efficient generation of multipotent mesenchymal stem cells from umbilical cord blood in stroma-free liquid culture. PLoS ONE, 5(12):e15689.
Far, E. Erfassung, Beurteilung und Bewertung von unerwünschten Arzneimittelwirkungen in der Onkologie. 2010, University of Zurich, Faculty of Medicine.
Yilmaz, Z; Ceschi, A; Rauber-Lüthy, C; Sauer, O; Stedtler, U; Prasa, D; Seidel, C; Hackl, E; Hoffmann-Walbeck, P; Gerber-Zupan, G; Bauer, K; Kupferschmidt, H; Kullak-Ublick, G A; Wilks, M (2010). Escitalopram causes fewer seizures in human overdose than citalopram. Clinical Toxicology, 48(3):207-212.
Loubière, L S; Vasilopoulou, E; Bulmer, J N; Taylor, P M; Stieger, B; Verrey, F; McCabe, C J; Franklyn, J A; Kilby, M D; Chan, S-Y (2010). Expression of thyroid hormone transporters in the human placenta and changes associated with intrauterine growth restriction. Placenta, 31(4):295-304.
Guyot, C; Lepreux, S; Combe, C; Sarrazy, V; Billet, F; Balabaud, C; Bioulac-Sage, P; Desmoulière, A (2010). Fibrogenic cell phenotype modifications during remodelling of normal and pathological human liver in cultured slices. Liver International, 30(10):1529-1540.
Peters, S; Egert, A; Stieger, B; Keller, F (2010). Functional identification of Arabidopsis ATSIP2 (At3g57520) as an alkaline α-galactosidase with a substrate specificity for raffinose and an apparent sink-specific expression patter. Plant & Cell Physiology, 51(10):1815-1819.
Hajda, J; Rentsch, K M; Gubler, C; Steinert, H; Stieger, B; Fattinger, K (2010). Garlic extract induces intestinal P-glycoprotein, but exhibits no effect on intestinal and hepatic CYP3A4 in humans. European Journal of Pharmaceutical Sciences, 41(5):729-735.
Franke, A; McGovern, D P; Barrett, J C; Wang, K; Radford-Smith, G L; Ahmad, T; Lees, C W; Balschun, T; Lee, J; Roberts, R; Anderson, C A; Bis, J C; Bumpstead, S; Ellinghaus, D; Festen, E M; Georges, M; Green, T; Haritunians, T; Jostins, L; Latiano, A; Mathew, C G; Montgomery, G W; Prescott, N J; Raychaudhuri, S; Rotter, J I; Schumm, P; Sharma, Y; Simms, L A; Taylor, K D; Whiteman, D; Wijmenga, C; Baldassano, R N; Barclay, M; Bayless, T M; Brand, S; Büning, C; Cohen, A; Colombel, J F; Cottone, M; Stronati, L; Denson, T; De Vos, M; D'Inca, R; Dubinsky, M; Edwards, C; Florin, T; Franchimont, D; Gearry, R; Glas, J; Van Gossum, A; Guthery, S L; Halfvarson, J; Verspaget, H W; Hugot, J P; Karban, A; Laukens, D; Lawrance, I; Lemann, M; Levine, A; Libioulle, C; Louis, E; Mowat, C; Newman, W; Panés, J; Phillips, A; Proctor, D D; Regueiro, M; Russell, R; Rutgeerts, P; Sanderson, J; Sans, M; Seibold, F; Steinhart, A H; Stokkers, P C; Torkvist, L; Kullak-Ublick, G; Wilson, D; Walters, T; Targan, S R; Brant, S R; Rioux, J D; D'Amato, M; Weersma, R K; Kugathasan, S; Griffiths, A M; Mansfield, J C; Vermeire, S; Duerr, R H; Silverberg, M S; Satsangi, J; Schreiber, S; Cho, J H; Annese, V; Hakonarson, H; Daly, M J; Parkes, M (2010). Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nature Genetics, 42(12):1118-1125.
Mwinyi, J; Kullak-Ublick, G A (2010). Hereditäre Defekte hepatobiliärer Transportproteine. Der Gastroenterologe, 5(1):39-48.
Bihl, F; Russmann, S; Gurtner, V; Di Giammarino, L; Pizzi-Bosman, L; Michel, M; Cerny, A; Hadengue, A; Majno, P; Giostra, E; Castelli, D; Mentha, G (2010). Hyperimmune anti-HBs plasma as alternative to commercial immunoglobulins for prevention of HBV recurrence after liver transplantation. BMC Gastroenterology, 10:71.
Annaert, P; Ye, Z W; Stieger, B; Augustijns, P (2010). Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1. Xenobiotica, 40(3):163-176.
Mwinyi, J; Nekvindová, J; Cavaco, I; Hofmann, Y; Pedersen, R S; Landman, E; Mkrtchian, S; Ingelman-Sundberg, M (2010). New insights into the regulation of CYP2C9 gene expression: the role of the transcription factor GATA-4. Drug Metabolism and Disposition, 38(3):415-421.
Non adherence - non response. Edited by: Kullak-Ublick, G A; Jetter, A (2010). Bern, CH: Hans Huber Verlag.
Jetter, A; Kullak-Ublick, G A (2010). Non adherence – non response. Therapeutische Umschau, 67(6):281-282.
Russmann, S; Jetter, A; Kullak-Ublick, G A (2010). Pharmacogenetics of drug-induced liver injury. Hepatology, 52(2):748-761.
Corti, N; Grimm, V; Kullak-Ublick, G A (2010). Polymedikation und Wechselwirkungen: Medikamente bei älteren Patienten richtig dosieren. Zahnarzt Praxis, (2):1-6.
Maggiore, G; Gonzales, E; Sciveres, M; Redon, M-J; Grosse, B; Stieger, B; Davit-Spraul, A; Fabre, M; Jacquemin, E (2010). Relapsing features of bile salt export pump deficiency after liver transplantation in two patients with progressive familial intrahepatic cholestasis type 2. Journal of Hepatology, 53(5):981-986.
Stieger, B (2010). Role of the bile salt export pump, BSEP, in acquired forms of cholestasis. Drug Metabolism Reviews, 42(3):437-445.
Klein, K; Jungst, C; Mwinyi, J; Stieger, B; Krempler, F; Patsch, W; Eloranta, J J; Kullak-Ublick, G A (2010). The Human Organic Anion Transporter Genes OAT5 and OAT7 Are Transactivated by Hepatocyte Nuclear Factor-1{alpha} (HNF-1{alpha}). Molecular Pharmacology, 78(6):1079-1087.
Curkovic, I; Lüthi, B; Franzen, D; Ceschi, A; Rudiger, A; Corti, N (2010). Trimethoprim/Sulfamethoxazole pharmacokinetics in two patients undergoing continuous venovenous hemodiafiltration. Annals of Pharmacotherapy, 44(10):1669-1672.
Motsko, S P; Russmann, S; Ming, E E; Singh, V P; Vendiola, R M; Jones, J K (2009). Effectiveness of rosuvastatin compared to other statins for the prevention of cardiovascular events-a cohort study in 395 039 patients from clinical practice. Pharmacoepidemiology and Drug Safety, 18(12):1214-1222.
Wojtal, K A; Eloranta, J J; Hruz, P; Gutmann, H; Drewe, J; Beglinger, C; Fried, M; Kullak-Ublick, G A; Vavricka, S R (2009). Changes in mRNA expression levels of solute carrier transporters in inflammatory bowel disease patients. Drug Metabolism and Disposition, 37(9):1871-1877.
Eloranta, J J; Hiller, C; Hausler, S; Stieger, B; Kullak-Ublick, G A (2009). Vitamin D3 and its nuclear receptor increase the expression and activity of the human proton-coupled folate transporter. Molecular Pharmacology, 76(5):1062-1071.
Tomalik-Scharte, D; Lütjohann, D; Doroshyenko, O; Frank, D; Jetter, A; Fuhr, U (2009). Plasma 4beta-Hydroxycholesterol: An Endogenous CYP3A Metric? Clinical Pharmacology and Therapeutics, 86(2):147-153.
Stieger, B (2009). Recent insights into the function and regulation of the bile salt export pump (ABCB11). Current Opinion in Lipidology, 20(3):176-181.
Kullak-Ublick, G A; Eloranta, J J (2009). Nuclear receptor regulation of bile acid transporters. In: Keppler, D; Beuers, U; Steihl, A; Trauner, M. Bile Acid Biology and Therapeutic Actions. Berlin: Springer, 111-114.
Klein, K; Kullak-Ublick, G A; Wagner, M; Trauner, M; Eloranta, J J (2009). Hepatocyte nuclear factor-4{alpha} and bile acids regulate human concentrative nucleoside transporter-1 gene expression. American Journal of Physiology. Gastrointestinal and Liver Physiology, 296(4):G936-G947.
Jetter, A; Kinzig, M; Rodamer, M; Tomalik-Scharte, D; Sörgel, F; Fuhr, U (2009). Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected? European Journal of Clinical Pharmacology, 65(4):411-417.
Perger, L; Rentsch, K M; Kullak-Ublick, G A; Verotta, D; Fattinger, K (2009). Oral heroin in opioid-dependent patients: Pharmacokinetic comparison of immediate and extended release tablets. European Journal of Pharmaceutical Sciences, 36(4-5):421-432.
Stieger, B; Ismair, M G; Guyot, C; Synal-Hermanns, U; Kullak-Ublick, G A (2009). Canalicular microdomains and bile formation. In: Keppler, D; Beuers, U; Stiehl, A; Trauner, M. Bile Acid Biology and Therapeutic Actions. Dordrecht, NL: Springer, 31-35.
Huber, M; Kullak-Ublick, G A; Kirch, W (2009). Drug information for patients - an update of long-term results: type of enquiries and patient characteristics. Pharmacoepidemiology and Drug Safety, 18(2):111-119.
Beuers, U; Kullak-Ublick, G A; Pusl, T; Rauws, E R; Rust, C (2009). Medical treatment of primary sclerosing cholangitis: A role for novel bile acids and other (post-)transcriptional modulators? Clinical Reviews in Allergy and Immunology, 36(1):52-61.
Lück, H; Kinzig, M; Jetter, A; Fuhr, U; Sörgel, F (2009). Mesalazine pharmacokinetics and NAT2 phenotype. European Journal of Clinical Pharmacology, 64(1):47-54.
Gee, J M W; Eloranta, J J; Ibbitt, J C; Robertson, J F R; Ellis, I O; Williams, T; Nicholson, R I; Hurst, H C (2009). Overexpression of TFAP2C in invasive breast cancer correlates with a poorer response to anti-hormone therapy and reduced patient survival. Journal of Pathology, 217(1):32-41.
Cattori, V; Tandon, R; Riond, Barbara; Pepin, A C; Lutz, H; Hofmann-Lehmann, Regina (2009). The kinetics of feline leukaemia virus shedding in experimentally infected cats are associated with infection outcome. Veterinary Microbiology, 133(3):292-296.
Huber, M; Kullak-Ublick, G A; Kirch, W (2009). 6 Jahre Erfahrungen mit einem Arzneimittelberatungsdienst für Patienten. Medizinische Klinik, 104(3):220-224.
Ismair, M G; Häusler, S; Stuermer, C A; Guyot, C; Meier, P J; Roth, J; Stieger, B (2009). ABC-transporters are localized in caveolin-1-positive and reggie-1-negative and reggie-2-negative microdomains of the canalicular membrane in rat hepatocytes. Hepatology, 49(5):1673-1682.
Jung, D. Advancing Bileology. 2009, University of Zurich, Faculty of Medicine.
Stieger, B; Arand, Michael (2009). Biotransformation und Detoxifizierung in der Leber. In: Schartl, M; Gessler, M; von Eckardstein, A. Biochemie und Molekularbiologie des Menschen. München: Urban und Fischer, 845-859.
Russmann, S; Kullak-Ublick, G A; Grattagliano, I (2009). Current concepts of mechanisms in drug-induced hepatotoxicity. Current Medicinal Chemistry, 16(23):3041-3053.
Le Vee, M; Lecureur, V; Moreau, A; Stieger, B; Fardel, O (2009). Differential regulation of drug transporter expression by hepatocyte growth factor in primary human hepatocytes. Drug Metabolism and Disposition, 37(11):2228-2235.
Corti, N; Heck, A; Rentsch, K; Zingg, W; Jetter, A; Stieger, B; Pauli-Magnus, C (2009). Effect of ritonavir on the pharmacokinetics of the benzimidazoles albendazole and mebendazole: an interaction study in healthy volunteers. European Journal of Clinical Pharmacology, 65(10):999-1006.
Doroshyenko, O; Fuhr, U; Kunz, D; Frank, D; Kinzig, M; Jetter, A; Reith, Y; Lazar, A; Taubert, D; Kirchheiner, J; Baum, M; Eisenbrand, G; Berger, F I; Bertow, D; Berkessel, A; Sörgel, F; Schömig, E; Tomalik-Scharte, D (2009). In vivo role of cytochrome P450 2E1 and glutathione-S-transferase activity for acrylamide toxicokinetics in humans. Cancer Epidemiology Biomarkers & Prevention, 18(2):433-443.
Leuthold, S; Hagenbuch, B; Mohebbi, N; Wagner, C A; Meier, P J; Stieger, B (2009). Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters. American Journal of Physiology. Cell Physiology, 296(3):C570-C582.
Russmann, S; Szeless, T; Bock, A; Kullak-Ublick, G A (2009). Natriumphosphat enthaltende Darmreinigungsmittel – eine Gefahr für die Niere? Swiss Medical Forum, 9(18):336-339.
Vee, M L; Lecureur, V; Stieger, B; Fardel, O (2009). Regulation of drug transporter expression in human hepatocytes exposed to the proinflammatory cytokines tumor necrosis factor-alpha or interleukin-6. Drug Metabolism and Disposition, 37(3):685-693.
Löfgren, S; Baldwin, R M; Carlerös, M; Terelius, Y; Fransson-Steen, R; Mwinyi, J; Waxman, D J; Ingelman-Sundberg, M (2009). Regulation of human CYP2C18 and CYP2C19 in transgenic mice: influence of castration, testosterone, and growth hormone. Drug Metabolism and Disposition, 37(7):1505-1512.
Muschler, E; Lal, J; Jetter, A; Rattay, A; Zanger, U; Zadoyan, G; Fuhr, U; Kirchheiner, J (2009). The role of human CYP2C8 and CYP2C9 variants in pioglitazone metabolism in vitro. Basic & Clinical Pharmacology & Toxicology, 105(6):374-379.
Eloranta, J J. Transcriptional regulation of genes encoding drug and bile acid transporters: implications for liver and intestinal diseases. 2009, University of Zurich, Faculty of Medicine.
Russmann, S; Lamerato, L; Motsko, S P; Pezzullo, J C; Faber, M D; Jones, J K (2008). Risk of further decline in renal function after the use of oral sodium phosphate or polyethylene glycol in patients with a preexisting glomerular filtration rate below 60 ml/min. American Journal of Gastroenterology, 103(11):2707-2716.
Tomalik-Scharte, D; Doroshyenko, O; Kirchheiner, J; Jetter, A; Lazar, A; Klaassen, T; Frank, D; Wyen, C; Fätkenheuer, G; Fuhr, U (2008). No role for the CYP3A5*3 polymorphism in intestinal and hepatic metabolism of midazolam. European Journal of Clinical Pharmacology, 64(10):1033-1035.
Stieger, B (2008). Turning over or turning around: hepatic phosphatidylcholine in the mouse model for progressive familial intrahepatic cholestasis type 3. Liver International, 28(7):908-910.
Lazar, A; Jetter, A (2008). Pharmakogenetik in der Onkologie: 5-Fluorouracil und die Dihydropyrimidin-Dehydrogenase. Deutsche Medizinische Wochenschrift, 133(28-29):1501-1504.
Zaïr, Z M; Eloranta, J J; Stieger, B; Kullak-Ublick, G A (2008). Pharmacogenetics of OATP (SLC21/SLCO), OAT and OCT (SLC22) and PEPT (SLC15) transporters in the intestine, liver and kidney. Pharmacogenomics, 9(5):597-624.
Klaassen, T; Jetter, A; Tomalik-Scharte, D; Kasel, D; Kirchheiner, J; Jaehde, U; Fuhr, U (2008). Assessment of urinary mephenytoin metrics to phenotype for CYP2C19 and CYP2B6 activity. European Journal of Clinical Pharmacology, 64(4):387-398.
Serra, A L; Braun, S C; Starke, A; Savoca, R; Hersberger, M; Russmann, S; Corti, N; Wüthrich, R P (2008). Pharmacokinetics and pharmacodynamics of cinacalcet in patients with hyperparathyroidism after renal transplantation. American Journal of Transplantation, 8(4):803-810.
Strautnieks, S S; Byrne, J A; Pawlikowska, L; Cebecauerová, D; Rayner, A; Dutton, L; Meier, Y; Antoniou, A; Stieger, B; Arnell, H; Özçay, F; Al-Hussaini, H F; Bassas, A F; Verkade, H J; Fischler, B; Németh, A; Kotalová, R; Shneider, B L; Cielecka-Kuszyk, J; McClean, P; Whitington, P F; Sokal, É; Jirsa, M; Wali, S H; Jankowska, I; Pawłowska, J; Mieli-Vergani, G; Knisely, A S; Bull, L N; Thompson, R J (2008). Severe bile salt export pump deficiency: 82 different ABCB11 mutations in 109 families. Gastroenterology, 134(4):1203-1214.
Le Vee, M; Gripon, P; Stieger, B; Fardel, O (2008). Down-regulation of organic anion transporter expression in human hepatocytes exposed to the proinflammatory cytokine interleukin 1beta. Drug Metabolism and Disposition, 36(2):217-222.
Wojtal, K A; Hoekstra, D; van IJzendoorn, S C D (2008). cAMP-dependent protein kinase A and the dynamics of epithelial cell surface domains: moving membranes to keep in shape. BioEssays, 30(2):146-155.
Russmann, S. Methodological options for the evaluation of drug safety: from spontaneous reports to pharmacoepidemiology. 2008, University of Zurich, Faculty of Medicine.
Meier, Y; Zodan, T; Lang, C; Zimmermann, R; Kullak-Ublick, G A; Meier, P J; Stieger, B; Pauli-Magnus, C (2008). Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump. World Journal of Gastroenterology, 14(1):38-45.
Gerber, P A; Pavlicek, V; Demartines, N; Zuellig, R; Pfammatter, T; Wüthrich, R; Weber, M; Spinas, G A; Lehmann, R (2008). Simultaneous islet-kidney vs pancreas-kidney transplantation in type 1 diabetes mellitus: a 5 year single centre follow-up. Diabetologia, 51(1):110-119.
Graf, H; Jüngst, C; Straub, G; Dogan, S; Hoffmann, R T; Jakobs, T; Reiser, M; Waggershauser, T; Helmberger, T; Walter, A; Walli, A; Seidel, D; Göke, B; Jüngst, D (2008). Chemoembolization combined with pravastatin improves survival in patients with hepatocellular carcinoma. Digestion, 78(1):34-38.
Hoekstra, H; Tian, Y; Jochum, W; Stieger, B; Graf, R; Porte, R J; Clavien, P A (2008). Dearterialization of the liver causes intrahepatic cholestasis due to reduced bile transporter expression. Transplantation, 85(8):1159-1166.
Wyen, C; Fuhr, U; Frank, D; Aarnoutse, R E; Klaassen, T; Lazar, A; Seeringer, A; Doroshyenko, O; Kirchheiner, J C; Abdulrazik, F; Schmeisser, N; Lehmann, C; Hein, W; Schömig, E; Burger, D M; Fätkenheuer, G; Jetter, A (2008). Effect of an antiretroviral regimen containing ritonavir boosted lopinavir on intestinal and hepatic CYP3A, CYP2D6 and P-glycoprotein in HIV-infected patients. Clinical Pharmacology and Therapeutics, 84(1):75-82.
Gui, C; Miao, Y; Thompson, L; Wahlgren, B; Mock, M; Stieger, B; Hagenbuch, B (2008). Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3. European Journal of Pharmacology, 584(1):57-65.
Darimont, J; Kullak-Ublick, G A (2008). Erkrankungen des Bilirubinstoffwechsels und der Gallensäurebildung. In: Riemann, J F; Mössner, J. Gastroenterologie: Das Referenzwerk für Klinik und Praxis, Volume 2: Leber, Galle, Pankreas. Stuttgart, New York: Thieme, 1680-1686.
Huber, M; Kullak-Ublick, G A (2008). Generika: Worauf sollte man beim Umstellen achten? Ars Medici, 16:1-5.
Huber, M; Kullak-Ublick, G A (2008). Generika: Worauf sollte man beim Umstellen achten? The Medical Journal (TMJ), 3:23-26.
Wyen, C; Hendra, H; Vogel, M; Hoffmann, C; Knechten, H; Brockmeyer, N H; Bogner, J R; Rockstroh, J; Esser, S; Jaeger, H; Harrer, T; Mauss, S; van Lunzen, J; Skoetz, N; Jetter, A; Groneuer, C; Fätkenheuer, G; Khoo, S H; Egan, D; Back, D J; Owen, A (2008). Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients. Journal of Antimicrobial Chemotherapy, 61(4):914-918.
Todesco, L; Bur, D; Brooks, H; Török, M; Landmann, L; Stieger, B; Krähenbühl, S (2008). Pharmacological manipulation of L-carnitine transport into L6 cells with stable overexpression of human OCTN2. Cellular and Molecular Life Sciences, 65(10):1596-1608.
Mosimann, K. Stabile Expression und funktionelle Charakterisierung des humanen, Natrium abhängigen, hepatozellulären Gallensäure-Aufnahmesystems in CHO-Zellen. 2008, University of Zurich, Faculty of Medicine.
Eloranta, J J; Kullak-Ublick, G A (2008). The role of FXR in disorders of bile acid homeostasis. Physiology, 23:286-295.
Jüngst, C; Sreejayan, N; Zündt, B; Müller, I; Spelsberg, F W; Hüttl, T P; Kullak-Ublick, G A; del Pozo, R; Jüngst, D; von Ritter, C (2008). Ursodeoxycholic acid reduces lipid peroxidation and mucin secretagogue activity in gallbladder bile of patients with cholesterol gallstones. European Journal of Clinical Investigation, 38(9):634-639.
Eloranta, J J; Kullak-Ublick, G A (2007). Enterohepatic bile acid transporters and transcriptional control of their expression. In: Young, G; Morris, M E. Drug Transporters: Molecular characterization and role in drug disposition. Hoboken: Wiley and Sons, 201-221.
Jüngst, C; Kullak-Ublick, G A (2007). Gallensteine – eine Leberkrankheit? Teil 1. Pathogenese. Schweiz Med Forum, 7(33):668-673.
Jüngst, C; Kullak-Ublick, G A (2007). Gallensteine – eine Leberkrankheit? Teil 2.: Klinik und Therapie. Swiss Medical Forum, 7:692-695.
Biber, J; Stieger, B; Stange, G; Murer, H (2007). Isolation of renal proximal tubular brush-border membranes. Nature Protocols, 2(6):1356-1359.
Corti, N; Kullak-Ublick, G A (2007). Pharmacogenetics. In: Blum, H E; Cox, D W; Häussinger, D; Janssen, P L M; Kullak-Ublick, G A. Genetics in Liver Diseases. Dordrecht (NL): Springer, 3-7.
Eloranta, J J; Kullak-Ublick, G A (2007). Regulation of hepatic and intestinal bile acid transport by FXR-controlled pathways. In: Keppler, D; Beuers, U; Leuschner, U; Stiehl, A; Trauner, M; Paumgartner, G. Bile Acids: Biological Actions and Clinical Relevance. Dordrecht (NL): Springer, 115-120.
Mange, J P; Stephan, Roger; Borel, Nicole; Wild, P; Kim, Kwang Sik; Pospischil, A; Lehner, Angelika (2006). Adhesive properties of Enterobacter sakazakii to human epithelial and brain microvascular endothelial cells. BMC Microbiology, 6:58.
Bauerfeind, P; Müllhaupt, B; Schöfl, R; Rösch, T; Schwizer, W; Wirth, H P; Kullak-Ublick, G A; Fried, M (2006). Gastro-Highlights 2006. Praxis, 95(46):1793-1804.
Fischer, W J; Altheimer, S; Cattori, V; Meier, P J; Dietrich, D R; Hagenbuch, B (2005). Organic anion transporting polypeptides expressed in liver and brain mediate uptake of microcystin. Toxicology and Applied Pharmacology, 203(3):257-263.
Cattori, V; Montfoort, Jessica E; Stieger, B; Landmann, L; Meijer, D K; Winterhalter, K H; Meier, P J; Hagenbuch, B (2001). Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3. Pflügers Archiv: European Journal of Physiology (Pflugers Archiv), 443(2):188-195.
Hagenbuch, N; Reichel, C; Stieger, B; Cattori, V; Fattinger, K E; Landmann, L; Meier, P J; Kullak-Ublick, G A (2001). Effect of phenobarbital on the expression of bile salt and organic anion transporters of rat liver. Journal of Hepatology, 34(6):881-887.
Ismair, M G; Stieger, B; Cattori, V; Hagenbuch, B; Fried, M; Meier, P J; Kullak-Ublick, G A (2001). Hepatic uptake of cholecystokinin octapeptide by organic anion-transporting polypeptides OATP4 and OATP8 of rat and human liver. Gastroenterology, 121(5):1185-1190.
Cattori, V; Hagenbuch, B; Hagenbuch, N; Stieger, B; Ha, R; Winterhalter, K E; Meier, P J (2000). Identification of organic anion transporting polypeptide 4 (Oatp4) as a major full-length isoform of the liver-specific transporter-1 (rlst-1) in rat liver. FEBS Letters, 474(2-3):242-245.
Fattinger, K; Cattori, V; Hagenbuch, B; Meier, P J; Stieger, B (2000). Rifamycin SV and rifampicin exhibit differential inhibition of the hepatic rat organic anion transporting polypeptides, Oatp1 and Oatp2. Hepatology, 32(1):82-86.
Cattori, V; Eckhardt, U; Hagenbuch, B (1999). Molecular cloning and functional characterization of two alternatively spliced Ntcp isoforms from mouse liver1. Biochimica et Biophysica Acta, 1445(1):154-159.
Reichel, C; Gao, B; Van Montfoort, J; Cattori, V; Rahner, C; Hagenbuch, B; Stieger, B; Kamisako, T; Meier, P J (1999). Localization and function of the organic anion-transporting polypeptide Oatp2 in rat liver. Gastroenterology, 117(3):688-695.
