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Delgado Magalhaes, Andreia Susana. Natural Anti-Tau Autoantibodies in Health and Disease. 2024, University of Zurich, Faculty of Science.
Liu, Yingjun; Guo, Jingjing; Matoga, Maja; Korotkova, Marina; Jakobsson, Per-Johan; Aguzzi, Adriano (2024). NG2 glia protect against prion neurotoxicity by inhibiting microglia-to-neuron prostaglandin E2 signaling. Nature Neuroscience, 27(8):1534-1544.
Reuss, Anna Maria. aDISCO: 3D Histology of Whole Archival Human Tissue Blocks. 2024, University of Zurich, Faculty of Science.
Heinzer, Daniel; Avar, Merve; Pfammatter, Manuela; Moos, Rita; Schwarz, Petra; Buhmann, Matthias T; Kuhn, Benjamin; Mauerhofer, Stefan; Rosenberg, Urs; Aguzzi, Adriano; Hornemann, Simone (2024). Advancing surgical instrument safety: A screen of oxidative and alkaline prion decontaminants using real-time quaking-induced conversion with prion-coated steel beads as surgical instrument mimetic. PLoS ONE, 19(6):e0304603.
Losa, Marco; Morsy, Yasser; Emmenegger, Marc; Manz, Salomon M; Schwarz, Petra; Aguzzi, Adriano; Scharl, Michael (2024). Longitudinal microbiome investigation throughout prion disease course reveals pre- and symptomatic compositional perturbations linked to short-chain fatty acid metabolism and cognitive impairment in mice. Frontiers in Microbiology, 15:1412765.
Binder, Nadine Felizitas; El Amki, Mohamad; Glück, Chaim; Middleham, William; Reuss, Anna Maria; Bertolo, Adrien; Thurner, Patrick; Deffieux, Thomas; Lambride, Chryso; Epp, Robert; Handelsmann, Hannah-Lea; Baumgartner, Philipp; Orset, Cyrille; Bethge, Philipp; Kulcsar, Zsolt; Aguzzi, Adriano; Tanter, Mickael; Schmid, Franca; Vivien, Denis; Wyss, Matthias Tasso; Luft, Andreas; Weller, Michael; Weber, Bruno; Wegener, Susanne (2024). Leptomeningeal collaterals regulate reperfusion in ischemic stroke and rescue the brain from futile recanalization. Neuron, 112(9):1456-1472.e6.
Zhang, Hui. Investigation of the Therapeutic Effect of an Fc-Domain Polythiophene Conjugate in Prion Diseases. 2024, University of Zurich, Faculty of Science.
Vladimirov, Nikita; Voigt, Fabian F; Naert, Thomas; Araujo, Gabriela R; Cai, Ruiyao; Reuss, Anna Maria; Zhao, Shan; Schmid, Patricia; Hildebrand, Sven; Schaettin, Martina; Groos, Dominik; Mateos, José María; Bethge, Philipp; Yamamoto, Taiyo; Aerne, Valentino; Roebroeck, Alard; Ertürk, Ali; Aguzzi, Adriano; Ziegler, Urs; Stoeckli, Esther; Baudis, Laura; Lienkamp, Soeren S; Helmchen, Fritjof (2024). Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for cleared samples. Nature Communications, 15(1):2679.
Brouwers, Sofie; Heimgartner, Raphael; Laptseva, Natallia; Aguzzi, Adriano; Ehl, Niklas F; Fehr, Thomas; Hitz, Felicitas; Jung, Hans H; Kälin, Joel; Manz, Markus G; Müllhaupt, Beat; Ruschitzka, Frank; Seeger, Harald; Stussi, Georg; Zweier, Markus; Flammer, Andreas J; Gerber, Bernhard; Schwotzer, Rahel (2024). Historic characteristics and mortality of patients in the Swiss Amyloidosis Registry. Swiss Medical Weekly, 154(2):3485.
Hruska-Plochan, Marian; Wiersma, Vera I; Betz, Katharina M; Mallona, Izaskun; Ronchi, Silvia; Maniecka, Zuzanna; Hock, Eva-Maria; Tantardini, Elena; Laferriere, Florent; Sahadevan, Sonu; Hoop, Vanessa; Delvendahl, Igor; Pérez-Berlanga, Manuela; Gatta, Beatrice; Panatta, Martina; van der Bourg, Alexander; Bohaciakova, Dasa; Sharma, Puneet; De Vos, Laura; Frontzek, Karl; Aguzzi, Adriano; Lashley, Tammaryn; Robinson, Mark D; Karayannis, Theofanis; Mueller, Martin; Hierlemann, Andreas; Polymenidou, Magdalini (2024). A model of human neural networks reveals NPTX2 pathology in ALS and FTLD. Nature, 626(8001):1073-1083.
Company, Carlos; Schmitt, Matthias Jürgen; Dramaretska, Yuliia; Serresi, Michela; Kertalli, Sonia; Jiang, Ben; Yin, Jiang-An; Aguzzi, Adriano; Barozzi, Iros; Gargiulo, Gaetano (2024). Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes. Nature Communications, 15(1):897.
Cervia-Hasler, Carlo; Brüningk, Sarah C; Hoch, Tobias; Fan, Bowen; Muzio, Giulia; Thompson, Ryan C; Ceglarek, Laura; Meledin, Roman; Westermann, Patrick; Emmenegger, Marc; Taeschler, Patrick; Zurbuchen, Yves; Pons, Michele; Menges, Dominik; Ballouz, Tala; Cervia-Hasler, Sara; Adamo, Sarah; Merad, Miriam; Charney, Alexander W; Puhan, Milo; Brodin, Petter; Nilsson, Jakob; Aguzzi, Adriano; Raeber, Miro E; Messner, Christoph B; Beckmann, Noam D; Borgwardt, Karsten; Boyman, Onur (2024). Persistent complement dysregulation with signs of thromboinflammation in active Long Covid. Science, 383(6680):eadg7942.
Aguzzi, Adriano (2024). Prion science and its unsung heroes. Science, 383(6680):eadn9424.
Wu, Jinming; Wang, Xue; Lakkaraju, Asvin; Sternke-Hoffmann, Rebecca; Qureshi, Bilal M; Aguzzi, Adriano; Luo, Jinghui (2024). Channel Activities of the Full-Length Prion and Truncated Proteins. ACS Chemical Neuroscience, 15(1):98-107.
Voigt, Fabian F; Reuss, Anna Maria; Naert, Thomas; Hildebrand, Sven; Schaettin, Martina; Hotz, Adriana L; Whitehead, Lachlan; Bahl, Armin; Neuhauss, Stephan C F; Roebroeck, Alard; Stoeckli, Esther T; Lienkamp, Soeren S; Aguzzi, Adriano; Helmchen, Fritjof (2024). Reflective multi-immersion microscope objectives inspired by the Schmidt telescope. Nature Biotechnology, 42(1):65-71.
Vladimirov, Nikita; Voigt, Fabian F; Naert, Thomas; Araujo, Gabriela R; Cai, Ruiyao; Reuss, Anna Maria; Zhao, Shan; Schmid, Patricia; Hildebrand, Sven; Schaettin, Martina; Groos, Dominik; Mateos, José María; Bethge, Philipp; Yamamoto, Taiyo; Aerne, Valentino; Roebroeck, Alard; Ertürk, Ali; Aguzzi, Adriano; Ziegler, Urs; Stoeckli, Esther; Baudis, Laura; Lienkamp, Soeren S; Helmchen, Fritjof (2023). The Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for large cleared samples. bioRxiv 2023.06.16, University of Zurich.
Kollai, Sarolta; Bereczki, Dániel; Glasz, Tibor; Hortobágyi, Tibor; Kovács, Tibor (2023). Early histopathological changes of secondary degeneration in the spinal cord after total MCA territory stroke. Scientific Reports, 13(1):21934.
Caredio, Davide; Koderman, Maruša; Frontzek, Karl; Sorce, Silvia; Nuvolone, Mario; Bremer, Juliane; Schwarz, Petra; Sellitto, Stefano; Streichenberger, Nathalie; Scheckel, Claudia; Aguzzi, Adriano (2023). Skeletal-Muscle Glutamine Synthase is Upregulated in Preclinical Prion Diseases. bioRxiv 564879, Cold Spring Harbor Laboratory.
Aguzzi, Adriano; Kampmann, Martin (2023). Neurodegeneration enters the era of functional genomics. Science, 381(6662):eadk5693.
Heinzer, Daniel; Avar, Merve; Pfammatter, Manuela; Moos, Rita; Schwarz, Petra; Buhmann, Matthias T; Kuhn, Benjamin; Mauerhofer, Stefan; Rosenberg, Urs; Aguzzi, Adriano; Hornemann, Simone (2023). A screen of alkaline and oxidative formulations for their inactivation efficacy of metal surface adsorbed prions using a steel-bead seed amplification assay. bioRxiv 546570, Cold Spring Harbor Laboratory.
Neupane, Sandesh; De Cecco, Elena; Aguzzi, Adriano (2023). The Hidden Cell-to-Cell Trail of α-Synuclein Aggregates. Journal of Molecular Biology, 435(12):167930.
Lakkaraju, Asvin KK; Tejero, Oliver; Guixà-González, Ramon; Cecco, Elena De; Jungo, Martina; Tsai, Ching-Ju; Mastromartino, Rocco; Marino, Jacopo; Deupi, Xavier; Hornemann, Simone; Schertler, Gebhard FX; Aguzzi, Adriano (2023). The adhesion GPCR Adgrd1 is a prion protein receptor and a mediator of prion cytotoxicity. bioRxiv 538801, Cold Spring Harbor Laboratory.
Amoudruz, Lucas; Economides, Athena; Arampatzis, Georgios; Koumoutsakos, Petros (2023). The stress-free state of human erythrocytes: Data-driven inference of a transferable RBC model. Biophysical Journal, 122(8):1517-1525.
Frick, Lukas. Design and Validation of Genome-Wide Arrayed Libraries for CRISPR Activation and Knockout. 2023, University of Zurich, Faculty of Science.
Emmenegger, Marc; Worth, Roland; Fiedler, Sebastian; Devenish, Sean R A; Knowles, Tuomas P J; Aguzzi, Adriano (2023). Protocol to determine antibody affinity and concentration in complex solutions using microfluidic antibody affinity profiling. STAR Protocols, 4:102095.
Reimann, Regina R; Puzio, Martina; Rosati, Antonella; Emmenegger, Marc; Schneider, Bernard L; Valdés, Pamela; Huang, Danzhi; Caflisch, Amedeo; Aguzzi, Adriano (2023). Rapid ex vivo reverse genetics identifies the essential determinants of prion protein toxicity. Brain Pathology, 33(2):e13130.
Binder, Nadine Felizitas; Amki, Mohamad El; Glück, Chaim; Middleham, William; Reuss, Anna Maria; Bertolo, Adrien; Thurner, Patrick; Deffieux, Thomas; Handelsmann, Hannah-Lea; Baumgartner, Philipp; Orset, Cyrille; Bethge, Philipp; Kulcsar, Zsolt; Aguzzi, Adriano; Tanter, Mickael; Vivien, Denis; Wyss, Matthias T; Luft, Andreas; Weller, Michael; Weber, Bruno; Wegener, Susanne (2023). Leptomeningeal collaterals regulate reperfusion in ischemic stroke. bioRxiv 529915, Cold Spring Harbor Laboratory.
Bencsik, Norbert; Oueslati Morales, Carlos Omar; Hausser, Angelika; Schlett, Katalin (2023). Endocytosis of AMPA receptors: Role in neurological conditions. In: Peñano, John Michael. Progress in Molecular Biology and Translational Science. United States: Elsevier, 59-97.
Emmenegger, Marc; De Cecco, Elena; Lamparter, David; Jacquat, Raphaël P B; Riou, Julien; Menges, Dominik; Ballouz, Tala; Ebner, Daniel; Schneider, Matthias M; Morales, Itzel Condado; Doğançay, Berre; Guo, Jingjing; Wiedmer, Anne; Domange, Julie; Imeri, Marigona; Moos, Rita; Zografou, Chryssa; Batkitar, Leyla; Madrigal, Lidia; Schneider, Dezirae; Trevisan, Chiara; Gonzalez-Guerra, Andres; Carrella, Alessandra; Dubach, Irina L; Xu, Catherine K; Meisl, Georg; Kosmoliaptsis, Vasilis; Malinauskas, Tomas; Burgess-Brown, Nicola; Puhan, Milo A; Aguzzi, Adriano; et al (2023). Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region. iScience, 26(2):105928.
Glebov, Oleg O; Williamson, David; Owen, Dylan M; Hortobágyi, Tibor; Troakes, Claire; Aarsland, Dag (2023). Structural synaptic signatures of Alzheimer's disease and dementia with Lewy bodies in the male brain. Neuropathology and Applied Neurobiology, 49(1):e12852.
Ging, Kathi. Identification of Transcription Factors Modulating beta-Glucocerebrosidase Activity. 2023, University of Zurich, Faculty of Science.
Catto, Francesca. Three-dimensional Histology and Its Applications in Pathology. 2023, University of Zurich, Faculty of Science.
Kirschenbaum, Daniel; Dadgar‐Kiani, Ehsan; Catto, Francesca; Voigt, Fabian F; Trevisan, Chiara; Bichsel, Oliver; Shirani, Hamid; Nilsson, K Peter R; Frontzek, Karl J; Paganetti, Paolo; Helmchen, Fritjof; Lee, Jin Hyung; Aguzzi, Adriano (2023). Whole‐brain microscopy reveals distinct temporal and spatial efficacy of anti‐Aβ therapies. EMBO Molecular Medicine, 15(1):e16789.
Groos, Dominik; Reuss, Anna Maria; Rupprecht, Peter; Stachniak, Tevye; Han, Shuting; Lewis, Christopher; Sych, Yaroslav; Wieckhorst, Martin; Karayannis, Theofanis; Aguzzi, Adriano; Helmchen, Fritjof (2023). Distinct hypothalamus-habenula circuits govern risk preference. bioRxiv 522571, Cold Spring Harbor Laboratory.
Koch, Christian; Fleischer, Juliane; Popov, Todor; Frontzek, Karl; Schreiner, Bettina; Roth, Patrick; Manz, Markus G; Unseld, Simone; Müller, Antonia M S; Russkamp, Norman F (2023). Diabetes insipidus and Guillain-Barré-like syndrome following CAR-T cell therapy: a case report. Journal for ImmunoTherapy of Cancer, 11:e006059.
Liu, Yingjun; Guo, Jingjing; Matoga, Maja; Korotkova, Marina; Jakobsson, Per-Johan; Aguzzi, Adriano (2023). NG2 glia protect against prion neurotoxicity by inhibiting prostaglandin E2 signaling. bioRxiv 535590, Cold Spring Harbor Laboratory.
Feher, Adam; Pethő, Zoltán; Szanto, Tibor G; Klekner, Álmos; Tajti, Gabor; Batta, Gyula; Hortobágyi, Tibor; Varga, Zoltan; Schwab, Albrecht; Panyi, Gyorgy (2022). Mapping the functional expression of auxiliary subunits of KCa1.1 in glioblastoma. Scientific Reports, 12(1):22023.
Avar, Merve; Heinzer, Daniel; Thackray, Alana M; Liu, Yingjun; Hruska‐Plochan, Marian; Sellitto, Stefano; Schaper, Elke; Pease, Daniel P; Yin, Jiang‐An; Lakkaraju, Asvin KK; Emmenegger, Marc; Losa, Marco; Chincisan, Andra; Hornemann, Simone; Polymenidou, Magdalini; Bujdoso, Raymond; Aguzzi, Adriano (2022). An arrayed genome‐wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate‐limiting for prion propagation. The EMBO Journal, 41(23):e112338.
Matamoros-Angles, A; Hervera, A; Soriano, J; Martí, E; Carulla, P; Llorens, F; Nuvolone, M; Aguzzi, Adriano; Ferrer, I; Gruart, A; Delgado-García, J M; Del Río, J A (2022). Analysis of co-isogenic prion protein deficient mice reveals behavioral deficits, learning impairment, and enhanced hippocampal excitability. BMC Biology, 20:17.
Liu, Yingjun; Senatore, Assunta; Sorce, Silvia; Nuvolone, Mario; Guo, Jingjing; Gümüş, Zeynep H; Aguzzi, Adriano (2022). Brain aging is faithfully modelled in organotypic brain slices and accelerated by prions. Communications Biology, 5(1):557.
Lemes, Emina. Elucidating PIKfyve Toxicity Pathways Using Unbiased Whole-Genome Screens. 2022, University of Zurich, Faculty of Science.
Fiedler, Sebastian; Devenish, Sean R A; Morgunov, Alexey S; Ilsley, Alison; Ricci, Francesco; Emmenegger, Marc; Kosmoliaptsis, Vasilis; Theel, Elitza S; Mills, John R; Sholukh, Anton M; Aguzzi, Adriano; Iwasaki, Akiko; Lynn, Andrew K; Knowles, Tuomas P J (2022). Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration. Scientific Reports, 12(1):19791.
Aguzzi, Adriano; Waeber, Gérard (2022). Swiss Medical Weekly: Quo vadis? Swiss Medical Weekly, 152:40030.
Schürch, Patrick M; Malinovska, Liliana; Hleihil, Mohammad; Losa, Marco; Hofstetter, Mara C; Wildschut, Mattheus H E; Lysenko, Veronika; Lakkaraju, Asvin K K; Maat, Christina A; Benke, Dietmar; Aguzzi, Adriano; Wollscheid, Bernd; Picotti, Paola; Theocharides, Alexandre P A (2022). Calreticulin mutations affect its chaperone function and perturb the glycoproteome. Cell Reports, 41(8):111689.
Paolicelli, Rosa C; Sierra, Amanda; Stevens, Beth; Tremblay, Marie-Eve; Aguzzi, Adriano; et al; Greter, Melanie; Peri, Francesca (2022). Microglia states and nomenclature: A field at its crossroads. Neuron, 110(21):3458-3483.
Aguzzi, Adriano (2022). The protean roles of neuroinflammation in trauma, infections, autoimmunity and neurodegeneration. Seminars in Immunology, 61-64:101655.
Varkoly, Gréta; Hortobágyi, Tibor G; Gebri, Enikő; Bencze, János; Hortobágyi, Tibor; Módis, László (2022). Expression Pattern of Tenascin-C, Matrilin-2, and Aggrecan in Diseases Affecting the Corneal Endothelium. Journal of Clinical Medicine, 11(20):5991.
Borlin, Petra R; Brazzola, Pierluigi; Frontzek, Karl; Zanoni, Paolo; Morscher, Raphael J; Hench, Jürgen; Frank, Stephan; Kottke, Raimund; Rushing, Elisabeth J; Goeggel Simonetti, Barbara; Steindl, Katharina; Guerreiro Stucklin, Ana S (2022). Cancer in children with biallelic BRCA1 variants and Fanconi anemia-like features: Report of a malignant brain tumor in a young child. Pediatric Blood & Cancer, 69(10):e29680.
Gilvesy, Abris; Husen, Evelina; Magloczky, Zsofia; Mihaly, Orsolya; Hortobágyi, Tibor; Kanatani, Shigeaki; Heinsen, Helmut; Renier, Nicolas; Hökfelt, Tomas; Mulder, Jan; Uhlen, Mathias; Kovacs, Gabor G; Adori, Csaba (2022). Spatiotemporal characterization of cellular tau pathology in the human locus coeruleus–pericoerulear complex by three-dimensional imaging. Acta Neuropathologica, 144(4):651-676.
Erhard, Florian; Saliba, Antoine-Emmanuel; Lusser, Alexandra; Toussaint, Christophe; Hennig, Thomas; Prusty, Bhupesh K; Kirschenbaum, Daniel; Abadie, Kathleen; Miska, Eric A; Friedel, Caroline C; Amit, Ido; Micura, Ronald; Dölken, Lars (2022). Time-resolved single-cell RNA-seq using metabolic RNA labelling. Nature Reviews. Methods Primers, 2(1):77.
Lakkaraju, Asvin K K; Sorce, Silvia; Senatore, Assunta; Nuvolone, Mario; Guo, Jingjing; Schwarz, Petra; Moos, Rita; Pelczar, Pawel; Aguzzi, Adriano (2022). Glial activation in prion diseases is selectively triggered by neuronal PrP$^{Sc}$. Brain Pathology, 32(5):e13056.
Hopfner, Franziska; Tietz, Anja K; Ruf, Viktoria C; Ross, Owen A; Koga, Shunsuke; Dickson, Dennis; Aguzzi, Adriano; et al (2022). Common Variants Near ZIC1 and ZIC4 in Autopsy‐Confirmed Multiple System Atrophy. Movement Disorders, 37(10):2110-2121.
Zhong, Wen; Barde, Swapnali; Mitsios, Nicholas; Adori, Csaba; Oksvold, Per; von Feilitzen, Kalle; O’Leary, Liam; Csiba, László; Hortobágyi, Tibor; Szocsics, Péter; Mechawar, Naguib; Maglóczky, Zsófia; Renner, Éva; Palkovits, Miklós; Uhlén, Mathias; Mulder, Jan; Hökfelt, Tomas (2022). The neuropeptide landscape of human prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America, 119(33):e2123146119.
Kaczmarczyk, Lech; Schleif, Melvin; Dittrich, Lars; Williams, Rhiannan H; Koderman, Maruša; Bansal, Vikas; Rajput, Ashish; Schulte, Theresa; Jonson, Maria; Krost, Clemens; Testaquadra, Fabio J; Bonn, Stefan; Jackson, Walker S (2022). Distinct translatome changes in specific neural populations precede electroencephalographic changes in prion-infected mice. PLoS Pathogens, 18(8):e1010747.
Frontzek, Karl; Bardelli, Marco; Senatore, Assunta; Henzi, Anna; Reimann, Regina R; Bedir, Seden; Marino, Marika; Hussain, Rohanah; Jurt, Simon; Meisl, Georg; Pedotti, Mattia; Mazzola, Federica; Siligardi, Giuliano; Zerbe, Oliver; Losa, Marco; Knowles, Tuomas; Lakkaraju, Asvin; Zhu, Caihong; Schwarz, Petra; Hornemann, Simone; Holt, Matthew G; Simonelli, Luca; Varani, Luca; Aguzzi, Adriano (2022). A conformational switch controlling the toxicity of the prion protein. Nature Structural & Molecular Biology, 29(8):831-840.
Sonkodi, Balázs; Resch, Miklós D; Hortobágyi, Tibor (2022). Is the Sex Difference a Clue to the Pathomechanism of Dry Eye Disease? Watch out for the NGF-TrkA-Piezo2 Signaling Axis and the Piezo2 Channelopathy. Journal of Molecular Neuroscience, 72(8):1598-1608.
McKenzie, Neil; Piconi, Gabriele; Culeux, Audrey; et al; Hornemann, Simone; Aguzzi, Adriano; Frontzek, Karl; Reimann, Regina (2022). Concordance of cerebrospinal fluid real‐time quaking‐induced conversion across the European Creutzfeldt–Jakob Disease Surveillance Network. European Journal of Neurology, 29(8):2431-2438.
Farkas, Melinda. The Effects of the Homocysteine Metabolism on the Pathogenesis of Alzheimer's Disease. 2022, University of Zurich, Faculty of Science.
Ni, Ruiqing; Chen, Zhenyue; Deán-Ben, Xosé Luís; Voigt, Fabian F; Kirschenbaum, Daniel; Shi, Gloria; Villois, Alessia; Zhou, Quanyu; Crimi, Alessandro; Arosio, Paolo; Nitsch, Roger M; Nilsson, K Peter R; Aguzzi, Adriano; Helmchen, Fritjof; Klohs, Jan; Razansky, Daniel (2022). Multiscale optical and optoacoustic imaging of amyloid-β deposits in mice. Nature Biomedical Engineering, 6(9):1031-1044.
Rupawala, Huzefa; Shah, Keshvi; Davies, Caitlin; Rose, Jamie; Colom-Cadena, Marti; Peng, Xianhui; Granat, Lucy; Aljuhani, Manal; Mizuno, Keiko; Troakes, Claire; Perez-Nievas, Beatriz Gomez; Morgan, Alan; So, Po-Wah; Hortobágyi, Tibor; Spires-Jones, Tara L; Noble, Wendy; Giese, Karl Peter (2022). Cysteine string protein alpha accumulates with early pre-synaptic dysfunction in Alzheimer’s disease. Brain Communications, 4(4):fcac192.
Hellwig, Lia; Brada, Muriel; Held, Ulrike; Hagmann, Cornelia; Bode, Peter; Frontzek, Karl; Frey, Bernhard; Brotschi, Barbara; Grass, Beate (2022). Association of perinatal sentinel events, placental pathology and cerebral MRI in neonates with hypoxic-ischemic encephalopathy receiving therapeutic hypothermia. Journal of Perinatology, 42(7):885-891.
Emmenegger, Marc; Fiedler, Sebastian; Brugger, Silvio Daniel; Devenish, Sean R A; Morgunov, Alexey S; Ilsley, Alison; Ricci, Francesco; Malik, Anisa Y; Scheier, Thomas; Batkitar, Leyla; Madrigal, Lidia; Rossi, Marco; Meisl, Georg; Lynn, Andrew K; Saleh, Lanja; von Eckardstein, Arnold; Knowles, Tuomas P J; Aguzzi, Adriano (2022). Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants. iScience, 25(8):104766.
Aguzzi, Adriano; Deimling, Andreas; Glatzel, Markus; Louis, David N; Wiestler, Otmar D (2022). Paul Kleihues (1936–2022), neuropathology innovator and entrepreneur. Brain Pathology, 32:e13073.
Gözen, Irep; Köksal, Elif Senem; Põldsalu, Inga; Xue, Lin; Spustova, Karolina; Pedrueza‐Villalmanzo, Esteban; Ryskulov, Ruslan; Meng, Fanda; Jesorka, Aldo (2022). Protocells: Milestones and Recent Advances. Small, 18(18):2106624.
Denninger, Viola; Xu, Catherine K; Meisl, Georg; Morgunov, Alexey S; Fiedler, Sebastian; Ilsley, Alison; Emmenegger, Marc; Malik, Anisa Y; Piziorska, Monika A; Schneider, Matthias M; Devenish, Sean R A; Kosmoliaptsis, Vasilis; Aguzzi, Adriano; Fiegler, Heike; Knowles, Tuomas P J (2022). Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV-2. ACS Infectious Diseases, 8(4):790-799.
Kirschenbaum, Daniel; Amit, Ido (2022). Brain metastases: Not all tumors are created equal. Neuron, 110(7):1097-1099.
Tosic, Lazar; Voglis, Stefanos; Reuss, Anna Maria; Rushing, Elisabeth Jane; Regli, Luca; Serra, Carlo (2022). Intra-, para-, and suprasellar nuclear protein of testis carcinoma with infiltration of cavernous sinus and clivus-a case report. Acta Neurochirurgica, 164(4):1105-1110.
Wu, Zhaofa; He, Kaikai; Chen, Yue; Li, Hongyu; Pan, Sunlei; Li, Bohan; Liu, Tingting; Xi, Fengxue; Deng, Fei; Wang, Huan; Du, Jiulin; Jing, Miao; Li, Yulong (2022). A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo. Neuron, 110(5):770-782.e5.
Gehlhausen, Jeff R; Little, Alicia J; Ko, Christine J; Emmenegger, Marc; et al; Aguzzi, Adriano (2022). Lack of association between pandemic chilblains and SARS-CoV-2 infection. Proceedings of the National Academy of Sciences of the United States of America, 119(9):e2122090119.
Datki, Zsolt; Balazs, Evelin; Galik, Bence; Sinka, Rita; Zeitler, Lavinia; Bozso, Zsolt; Kalman, Janos; Hortobagyi, Tibor; Galik-Olah, Zita (2022). The interacting rotifer-biopolymers are anti- and disaggregating agents for human-type beta-amyloid in vitro. International journal of biological macromolecules, 201:262-269.
Maccio, Umberto; Zinkernagel, Annelies S; Schuepbach, Reto; Probst-Mueller, Elsbeth; Frontzek, Karl; Brugger, Silvio D; Hofmaenner, Daniel Andrea; Moch, Holger; Varga, Zsuzsanna (2022). Long-Term Persisting SARS-CoV-2 RNA and Pathological Findings: Lessons Learnt From a Series of 35 COVID-19 Autopsies. Frontiers in Medicine, 9:778489.
Emmenegger, Marc; Kumar, Sreedhar Saseendran; Emmenegger, Vishalini; Malinauskas, Tomas; Buettner, Thomas; Rosen, Laura E; Schierack, Peter; Sprinzl, Martin F; Sommer, Clemens J; Lackner, Karl J; Aguzzi, Adriano; Roggenbuck, Dirk; Frauenknecht, Katrin Barbara Magda (2022). Correction: Anti-prothrombin autoantibodies enriched after infection with SARS-CoV-2 and influenced by strength of antibody response against SARS-CoV-2 proteins. PLoS Pathogens, 18(2):e1010289.
Lohaus, Niklas; Mader, Cäcilia; Jelcic, Ilijas; Reimann, Regina; Huellner, Martin W (2022). Acute Disseminated Encephalomyelitis in FET PET/MR. Clinical Nuclear Medicine, 47(2):e137-e139.
Schneider, Matthias M; Emmenegger, Marc; Xu, Catherine K; Condado Morales, Itzel; Meisl, Georg; Turelli, Priscilla; Zografou, Chryssa; Zimmermann, Manuela R; Frey, Beat M; Fiedler, Sebastian; Denninger, Viola; Jacquat, Raphaël PB; Madrigal, Lidia; Ilsley, Alison; Kosmoliaptsis, Vasilis; Fiegler, Heike; Trono, Didier; Knowles, Tuomas PJ; Aguzzi, Adriano (2022). Microfluidic characterisation reveals broad range of SARS-CoV-2 antibody affinity in human plasma. Life Science Alliance, 5(2):e202101270.
Carta, Manfredi; Aguzzi, Adriano (2022). Molecular foundations of prion strain diversity. Current Opinion in Neurobiology, 72:22-31.
Iring, András; Tóth, Adrián; Baranyi, Mária; Otrokocsi, Lilla; Módis, László V; Gölöncsér, Flóra; Varga, Bernadett; Hortobágyi, Tibor; Bereczki, Dániel; Dénes, Ádám; Sperlágh, Beáta (2022). The dualistic role of the purinergic P2Y12-receptor in an in vivo model of Parkinson's disease: Signalling pathway and novel therapeutic targets. Pharmacological Research, 176:106045.
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Carta, Manfredi. Genomic Heterogeneity in Prion Disease. 2021, University of Zurich, Faculty of Science.
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Wulf, Marie-Angela. PrPC-dependent Electrophysiological Phenotypes of Hippocampal CA1 Pyramidal Neurons in Health and Disease. 2021, University of Zurich, Faculty of Science.
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Li, Bei; Chen, Meiling; Aguzzi, Adriano; Zhu, Caihong (2021). The role of macrophage scavenger receptor 1 (Msr1) in prion pathogenesis. Journal of Molecular Medicine, 99(6):877-887.
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Lidón, Laia; Llaó-Hierro, Laura; Nuvolone, Mario; Aguzzi, Adriano; Ávila, Jesús; Ferrer, Isidro; del Río, José Antonio; Gavín, Rosalina (2021). Tau Exon 10 Inclusion by PrPC through Downregulating GSK3β Activity. International Journal of Molecular Sciences, 22(10):5370.
Frauenknecht, Katrin Barbara Magda. Neuropathology of Experimental Antiphospholipid Syndrome (eAPS). 2021, University of Zurich, Faculty of Medicine.
Love, Christopher J; Kirschenbaum, Daniel; Selim, Magdy; Lo, Eng H; Rushing, Elisabeth; Spector, Myron; Aguzzi, Adriano (2021). Observation of Collagen-Containing Lesions After Hematoma Resolution in Intracerebral Hemorrhage. Stroke, 52(5):1856-1860.
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Gramatzki, Dorothee; Felsberg, Jörg; Roth, Patrick; Kaulich, Kerstin; von Deimling, Andreas; Rushing, Elisabeth Jane; Reifenberger, Guido; Weller, Michael (2021). The molecular evolution of glioblastoma treated by gross total resection alone. Neuro-Oncology, 23(2):334-336.
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Henzi, Anna. The Prion Protein and Its Receptor Adgrg6 in Peripheral Demyelinating Diseases. 2021, University of Zurich, Faculty of Science.
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De Cecco, Elena; Celauro, Luigi; Vanni, Silvia; Grandolfo, Micaela; Bistaffa, Edoardo; Moda, Fabio; Aguzzi, Adriano; Legname, Giuseppe (2020). The uptake of tau amyloid fibrils is facilitated by the cellular prion protein and hampers prion propagation in cultured cells. Journal of Neurochemistry, 155(5):577-591.
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Ventura, Elisa. Extracellular control of TGF-β signaling in glioma. 2017, University of Zurich, Faculty of Science.
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Li, Bei. Establishment of An Automated Digital Prion Infectivity Cell Assay and PrP-HPFRET Based High-throughput siRNA Screening Platform. 2016, University of Zurich, Faculty of Science.
Goniotaki, Despoina. Inhibition of Group I Metabotropic Glutamate Receptors (mGluR1 and mGluR5) Protects Against Prion-Induced Toxicity. 2016, University of Zurich, Faculty of Science.
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Neidert, Marian Christoph; Regli, Luca; Rushing, Elisabeth (2016). Coexisting pituicytoma and pituitary adenoma; a second coincidence?—reply. Human Pathology, 55:205-206.
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Einsiedler, Melanie. Investigation of the Role of Glial Cells in Prion Toxicity and a Potential Function of PrPC as a Cell Death Transducer. 2016, University of Zurich, Faculty of Science.
Requena, Jesús R; Kristensson, Krister; Korth, Carsten; Zurzolo, Chiara; Simmons, Marion; Aguilar-Calvo, Patricia; Aguzzi, Adriano; Andreoletti, Olivier; Benestad, Sylvie L; Böhm, Reinhard; Brown, Karen; Calgua, Byron; del Río, José Antonio; Espinosa, Juan Carlos; Girones, Rosina; Godsave, Sue; Hoelzle, Ludwig E; Knittler, Michael R; Kuhn, Franziska; Legname, Giuseppe; Laeven, Paul; Mabbott, Neil; Mitrova, Eva; Müller-Schiffmann, Andreas; Nuvolone, Mario; Peters, Peter J; Raeber, Alex; Roth, Klaus; Schmitz, Matthias; Schroeder, Björn; Sonati, Tiziana; Stitz, Lothar; Taraboulos, Albert; Torres, Juan María; Yan, Zheng-Xin; Zerr, Inga (2016). The Priority position paper: protecting Europe´s food chain from prions. Prion, 10(3):165-181.
Zhu, Caihong; Herrmann, Uli S; Falsig, Jeppe; Abakumova, Irina; Nuvolone, Mario; Schwarz, Petra; Frauenknecht, Katrin; Rushing, Elisabeth J; Aguzzi, Adriano (2016). A neuroprotective role for microglia in prion diseases. Journal of Experimental Medicine, 213(6):1047-1059.
Forny, Patrick; Schumann, Anke; Mustedanagic, Merima; Mathis, Déborah; Wulf, Marie-Angela; Nägele, Nadine; Langhans, Claus-Dieter; Zhakupova, Assem; Heeren, Joerg; Scheja, Ludger; Fingerhut, Ralph; Peters, Heidi L; Hornemann, Thorsten; Thony, Beat; Kölker, Stefan; Burda, Patricie; Froese, D Sean; Devuyst, Olivier; Baumgartner, Matthias R (2016). Novel mouse models of methylmalonic aciduria recapitulate phenotypic traits with a genetic dosage effect. Journal of Biological Chemistry, 291(39):20563-20573.
Klein, Klaus U; Johannes, Amelie; Brückner, Melanie; Thomas, Rainer; Matthews, Stephan; Frauenknecht, Katrin; Leukel, Petra; Mazur, Johanna; Poplawski, Alicia; Muellenbach, Ralf; Sommer, Clemens J; Thal, Serge C; Engelhard, Kristin (2016). Systemic PaO2 oscillations cause mild brain injury in a pig model. Critical Care Medicine, 44(5):e253-e263.
Seystahl, Katharina; Stoecklein, Veit; Schüller, Ulrich; Rushing, Elisabeth; Nicolas, Guillaume; Schäfer, Niklaus; Ilhan, Harun; Pangalu, Athina; Weller, Michael; Tonn, Jörg-Christian; Sommerauer, Michael; Albert, Nathalie L (2016). Somatostatin-receptor-targeted radionuclide therapy for progressive meningioma: benefit linked to 68Ga-DOTATATE/-TOC uptake. Neuro-Oncology, 18(11):1538-1547.
Gramatzki, Dorothee; Dehler, Silvia; Rushing, Elisabeth Jane; Zaugg, Kathrin; Hofer, Silvia; Yonekawa, Yasuhiro; Bertalanffy, Helmut; Valavanis, Anton; Korol, Dimitri; Rohrmann, Sabine; Pless, Miklos; Oberle, Joachim; Roth, Patrick; Ohgaki, Hiroko; Weller, Michael (2016). Glioblastoma in the canton of Zurich, Switzerland revisited: 2005 to 2009. Cancer, 122(14):2206-2215.
Hickmann, Anne-Katrin (2016). In Dubio Pro Therapia: Unexpected Recovery after Palliative Endoscopic Third Ventriculostomy and Temozolomide Chemotherapy in a Patient with Progressive Glioblastoma multiforme. International Journal of Neurology and Neurotherapy, 3(2):3:047.
Aguzzi, Adriano; Altmeyer, Matthias (2016). Phase separation: linking cellular compartmentalization to disease. Trends in Cell Biology, 26(7):547-558.
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Theocharides, Alexandre P; Lundberg, Pontus; Lakkaraju, Asvin K K; Lysenko, Veronika; Myburgh, Renier; Aguzzi, Adriano; Skoda, Radek C; Manz, Markus G (2016). Homozygous Calreticulin mutations in patients with myelofibrosis lead to acquired myeloperoxidase deficiency. Blood, 127(25):3253-3259.
Szabo, E; Schneider, H; Seystahl, K; Rushing, E J; Herting, F; Weidner, K M; Weller, M (2016). Autocrine VEGFR1 and VEGFR2 signaling promotes survival in human glioblastoma models in vitro and in vivo. Neuro-Oncology, 18(9):1242-1252.
Tschuor, Christoph; Kachaylo, Ekaterina; Limani, Përparim; Raptis, Dimitri A; Linecker, Michael; Tian, Yinghua; Herrmann, Uli; Grabliauskaite, Kamile; Weber, Achim; Columbano, Amedeo; Graf, Rolf; Humar, Bostjan; Clavien, Pierre-Alain (2016). Constitutive androstane receptor (Car)-driven regeneration protects liver from failure following tissue loss. Journal of Hepatology, 65(1):66-74.
Haybaeck, Johannes; Heikenwalder, Mathias; Klevenz, Britta; Schwarz, Petra; Margalith, Ilan; Bridel, Claire; Mertz, Kirsten; Zirdum, Elizabeta; Petsch, Benjamin; Fuchs, Thomas J; Stitz, Lothar; Aguzzi, Adriano (2016). Correction: Aerosols transmit prions to immunocompetent and immunodeficient mice. PLoS Pathogens, 12(2):e1005463.
Weller, Michael; Nabors, Louis Burt; Gorlia, Thierry; Leske, Henning; Rushing, Elisabeth J; Bady, Pierre; Hicking, Christine; Perry, James; Hong, Yong-Kil; Roth, Patrick; Wick, Wolfgang; Goodman, Simon L; Hegi, Monika E; Picard, Martin; Moch, Holger; Straub, Josef; Stupp, Roger (2016). Cilengitide in newly diagnosed glioblastoma: biomarker expression and outcome. OncoTarget, 7(12):15018-15032.
Sommerauer, M; Burkhardt, J K; Frontzek, K; Rushing, E; Buck, A; Krayenbuehl, N; Weller, M; Schaefer, N; Kuhn, F P (2016). 68Gallium-DOTATATE PET in meningioma: A reliable predictor of tumor growth rate? Neuro-Oncology, 18(7):1021-1027.
Kerz, T; Beyer, C; Mole, D; Oswald, S; Frauenknecht, K; von Loewenich, F D; Schwanz, T (2016). Abszedierende Pilzenzephalitis durch C. bantiana bei einer immunsupprimierten Patientin. Der Nervenarzt, 87(2):191-194.
Frontzek, Karl; Lutz, Mirjam I; Aguzzi, Adriano; Kovacs, Gabor G; Budka, Herbert (2016). Amyloid-β pathology and cerebral amyloid angiopathy are frequent in iatrogenic Creutzfeldt-Jakob disease after dural grafting. Swiss Medical Weekly, 146:w14287.
Frauenknecht, Katrin; Diederich, Kai; Leukel, Petra; Bauer, Henrike; Schäbitz, Wolf-Rüdiger; Sommer, Clemens J; Minnerup, Jens (2016). Functional improvement after photothrombotic stroke in rats is associated with different patterns of dendritic plasticity after g-csf treatment and g-csf treatment combined with concomitant or sequential constraint-induced movement therapy. PLoS ONE, 11(1):e0146679.
Galimov, Artur; Merry, Troy L; Luca, Edlira; Rushing, Elisabeth J; Mizbani, Amir; Turcekova, Katarina; Hartung, Angelika; Croce, Carlo M; Ristow, Michael; Krützfeldt, Jan (2016). microRNA-29a in adult muscle stem cells controls skeletal muscle regeneration during injury and exercise downstream of fibroblast growth factor-2. Stem Cells, 34(3):768-780.
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Hofer, Silvia; Berthod, Grégoire; Riklin, Christian; Rushing, Elisabeth; Feilchenfeldt, Jonas (2016). BRAF V600E mutation: A treatable driver mutation in pleomorphic xanthoastrocytoma (PXA). Acta Oncologica, 55(1):122-123.
Aguzzi, Adriano; Lakkaraju, Asvin K K (2016). Cell biology of prions and prionoids: a status report. Trends in Cell Biology, 26(1):40-51.
Gramatzki, Dorothee; Roth, P; Felsberg, J; Hofer, S; Rushing, E J; Hentschel, B; Westphal, M; Krex, D; Simon, M; Schnell, O; Wick, W; Reifenberger, G; Weller, M (2016). Chemotherapy for intracranial ependymoma in adults. BMC Cancer, 16(1):287.
Gugger, Alenka; Barnhill, Raymond L; Seifert, Burkhardt; Dehler, Silvia; Moch, Holger; Lugassy, Claire; Marques-Maggio, Ewerton; Rushing, Elisabeth J; Mihic-Probst, Daniela (2016). Cutaneous melanoma with brain metastasis: Report of 193 patients with new observations. PLoS ONE, 11(5):e0156115.
Reimann, Regina R; Sonati, Tiziana; Hornemann, Simone; Herrmann, Uli S; Arand, Michael; Hawke, Simon; Aguzzi, Adriano (2016). Differential toxicity of antibodies to the prion protein. PLoS Pathogens, 12(1):e1005401.
Seredenina, Tamara; Nayernia, Zeynab; Sorce, Silvia; Maghzal, Ghassan J; Filippova, Aleksandra; Ling, Shuo-Chien; Basset, Olivier; Plastre, Olivier; Daali, Youssef; Rushing, Elisabeth J; Giordana, Maria T; Cleveland, Don W; Aguzzi, Adriano; Stocker, Roland; Krause, Karl-Heinz; Jaquet, Vincent (2016). Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis. Free Radical Biology & Medicine, 97:95-108.
Wolpert, Fabian; Grotzer, Michael A; Niggli, Felix; Zimmermann, Dieter; Rushing, Elisabeth; Bode-Lesniewska, Beata (2016). Ewing's Sarcoma as a Second Malignancy in Long-Term Survivors of Childhood Hematologic Malignancies. Sarcoma, 2016:5043640.
Wirsching, Hans-Georg; Morel, Corinne; Gmür, Corinne; Neidert, Marian Christoph; Baumann, Christian Richard; Valavanis, Antonios; Rushing, Elisabeth Jane; Krayenbühl, Niklaus; Weller, Michael (2016). Predicting outcome of epilepsy after meningioma resection. Neuro-Oncology, 18(7):1002-1010.
Nuvolone, Mario; Hermann, Mario; Sorce, Silvia; Russo, Giancarlo; Tiberi, Cinzia; Schwarz, Petra; Minikel, Eric; Sanoudou, Despina; Pelczar, Pawel; Aguzzi, Adriano (2016). Strictly co-isogenic C57BL/6J-Prnp−/−mice: A rigorous resource for prion science. Journal of Experimental Medicine, 213(3):313-327.
Soliman, Radwa K; Budai, Caterina; Mundada, Pravin; Aljohani, Bakar; Rushing, Elisabeth J; Kollias, Spyros S (2016). Suprasellar pilocytic astrocytoma in an adult with hemorrhage and leptomeningeal dissemination: case report and review of literature. Radiology Case Reports, 11(4):411-418.
Neidert, Marian C; Leske, Henning; Burkhardt, Jan-Karl; Kollias, Spyros S; Capper, David; Schrimpf, Daniel; Regli, Luca; Rushing, Elisabeth J (2016). Synchronous pituitary adenoma and pituicytoma. Human Pathology, 47(1):138-143.
Kiessling, Michael K; Curioni-Fontecedro, Alessandra; Samaras, Panagiotis; Lang, Silvia; Scharl, Michael; Aguzzi, Adriano; Oldrige, Derek A; Maris, John M; Rogler, Gerhard (2016). Targeting the mTOR Complex by Everolimus in NRAS Mutant Neuroblastoma. PLoS ONE, 11(1):e0147682.
Silginer, M; Burghardt, I; Gramatzki, D; Bunse, L; Leske, H; Rushing, E J; Hao, N; Platten, M; Weller, M; Roth, P (2016). The aryl hydrocarbon receptor links integrin signaling to the TGF-β pathway. Oncogene, 35(25):3260-3271.
Budka, Herbert; Will, Robert G (2015). The end of the BSE saga: do we still need surveillance for human prion diseases? Swiss Medical Weekly, 145(w14212):online.
Frontzek, Karl; Moos, Rita; Schaper, Elke; Jann, Lukas; Herfs, Gregor; Zimmermann, Dieter R; Aguzzi, Adriano; Budka, Herbert (2015). Iatrogenic and sporadic Creutzfeldt-Jakob disease in 2 sisters without mutation in the prion protein gene. Prion, 9(6):444-448.
Nuvolone, Mario; Aguzzi, Adriano (2015). Altered monoaminergic systems and depressive-like behavior in congenic prion protein nnock-out mice. Journal of Biological Chemistry, 290(43):26350.
Hruska-Plochan, Marian; Li, Bei; Kyburz, Diego; Krützfeldt, Jan; Landmesser, Ulf; Aguzzi, Adriano; Polymenidou, Magdalini (2015). New and emerging roles of small RNAs in neurodegeneration, muscle, cardiovascular and inflammatory diseases. Swiss Medical Weekly:w14192.
Schreiner, Bettina; Romanelli, Elisa; Liberski, Pawel; Ingold-Heppner, Barbara; Sobottka-Brillout, Bettina; Hartwig, Tom; Chandrasekar, Vijay; Johannssen, Helge; Zeilhofer, Hanns Ulrich; Aguzzi, Adriano; Heppner, Frank; Kerschensteiner, Martin; Becher, Burkhard (2015). Astrocyte depletion impairs redox homeostasis and triggers neuronal loss in the adult CNS. Cell Reports, 12(9):1377-1384.
Reuss, David E; Kratz, Annekathrin; Sahm, Felix; Capper, David; Schrimpf, Daniel; Koelsche, Christian; Hovestadt, Volker; Bewerunge-Hudler, Melanie; Jones, David T W; Schittenhelm, Jens; Mittelbronn, Michel; Rushing, Elisabeth; Simon, Matthias; Westphal, Manfred; Unterberg, Andreas; Platten, Michael; Paulus, Werner; Reifenberger, Guido; Tonn, Joerg-Christian; Aldape, Kenneth; Pfister, Stefan M; Korshunov, Andrey; Weller, Michael; Herold-Mende, Christel; Wick, Wolfgang; Brandner, Sebastian; von Deimling, Andreas (2015). Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities. Acta Neuropathologica, 130(3):407-417.
Baral, Pravas Kumar; Swayampakula, Mridula; Aguzzi, Adriano; James, Michael N G (2015). X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. Journal of Structural Biology, 192(1):37-47.
Herrmann, Uli S; Schütz, Anne K; Shirani, Hamid; Huang, Danzhi; Saban, Dino; Nuvolone, Mario; Li, Bei; Ballmer, Boris; Åslund, Andreas K O; Mason, Jeffrey J; Rushing, Elisabeth; Budka, Herbert; Nystrom, Sofie; Hammarstrom, Per; Böckmann, Anja; Caflisch, Amedeo; Meier, Beat H; Nilsson, K Peter R; Hornemann, Simone; Aguzzi, Adriano (2015). Structure-based drug design identifies polythiophenes as antiprion compounds. Science Translational Medicine, 7(299):299ra123.
Könnecke, Helen K; Rushing, Elisabeth J; Neidert, Marian Christoph; Reimann, Regina; Regli, Luca; Bozinov, Oliver; Burkhardt, Jan-Karl (2015). Heterogeneous Appearance of Central Nervous System Involvement in Malignant Mixed Müllerian Tumors. Journal of Neurological Surgery. Part A: Central European Neurosurgery, 77(05):447-451.
Cudalbu, Cristina; Craveiro, Melanie; Mlynárik, Vladimir; Bremer, Juliane; Aguzzi, Adriano; Gruetter, Rolf (2015). In Vivo Longitudinal 1H MRS Study of Transgenic Mouse Models of Prion Disease in the Hippocampus and Cerebellum at 14.1 T. Neurochemical Research, 40(12):2639-2646.
Love, Seth; Perry, Arie; Budka, Herbert (2015). Greenfield's Neuropathology. Boca Raton: CRC Press.
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Woernle, C M; Péus, D; Hofer, S; Rushing, E J; Held, U; Bozinov, O; Krayenbühl, N; Weller, M; Regli, L (2015). Efficacy of surgery and further treatment of progressive glioblastoma. World Neurosurgery, 84(2):301-307.
Aguzzi, Adriano (2015). Authoring scientific papers: a perspective from the trenches. Swiss Medical Weekly, 145:w14107.
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Neidert, Marian Christoph; Leske, Henning; Burkhardt, Jan-Karl; Rushing, Elisabeth Jane; Bozinov, Oliver (2015). A 44-year old male with right-sided facial numbness. Dura-associated extranodal marginal zone B cell lymphoma (MALT lymphoma). Brain Pathology, 25(1):113-114.
Nuvolone, Mario; Palladini, G; Merlini, G (2015). Amyloidosis at a molecular level: General overview and focus on AL amyloidosis. In: Picken, M M; Dogan, A; Herrera, G. Amyloid and Related Disorders: Surgical Pathology and Clinical Correlations. New York: Springer Verlag, 9-29.
Blumenthal, Deborah T; Rankin, Cathryn; Stelzer, Keith J; Spence, Alexander M; Sloan, Andrew E; Moore, Dennis F; Padula, Gilbert D A; Schulman, Susan B; Wade, Mark L; Rushing, Elisabeth J (2015). A Phase III study of radiation therapy (RT) and O6-benzylguanine + BCNU versus RT and BCNU alone and methylation status in newly diagnosed glioblastoma and gliosarcoma: Southwest Oncology Group (SWOG) study S0001. International Journal of Clinical Oncology, 20(4):650-658.
Assar, H; Topakian, R; Weis, S; Rahimi, J; Trenkler, J; Hoftberger, R; Aboulenein-Djamshidian, F; Strobel, T; Budka, H; Yull, H; Head, M W; Ironside, J W; Kovacs, G G (2015). A case of variably protease-sensitive prionopathy treated with doxycyclin. Journal of Neurology, Neurosurgery, and Psychiatry, 86(7):816-818.
Sanchez-Juan, Pascual; Bishop, Matthew T; Kovacs, Gabor G; Calero, Miguel; Aulchenko, Yurii S; Ladogana, Anna; Boyd, Alison; Lewis, Victoria; Ponto, Claudia; Calero, Olga; Poleggi, Anna; Carracedo, Ángel; van der Lee, Sven J; Ströbel, Thomas; Rivadeneira, Fernando; Hofman, Albert; Haïk, Stéphane; Combarros, Onofre; Berciano, José; Uitterlinden, Andre G; Collins, Steven J; Budka, Herbert; Brandel, Jean-Philippe; Laplanche, Jean Louis; Pocchiari, Maurizio; Zerr, Inga; Knight, Richard S G; Will, Robert G; van Duijn, Cornelia M (2015). A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk. PLoS ONE, 10(4):e0123654.
Klein, Andrea; Robb, Stephanie; Rushing, Elisabeth; Liu, Wei-Wei; Belaya, Kasiaryna; Beeson, David (2015). Congenital Myasthenic Syndrome caused by mutations in DPAGT. Neuromuscular Disorders : NMD, 25(3):253-256.
Petersen, Jens A; Kuntzer, Thierry; Fischer, Dirk; von der Hagen, Maja; Huebner, Angela; Kana, Veronika; Lobrinus, Johannes A; Kress, Wolfram; Rushing, Elisabeth J; Sinnreich, Michael; Jung, Hans H (2015). Dysferlinopathy in Switzerland: clinical phenotypes and potential founder effects. BMC Neurology, 15(182):online.
McKinney, Nicole; Yuan, Liangping; Zhang, Hongying; Liu, Jingbo; Cho, Yoon-Jae; Rushing, Elisabeth; Schniederjan, Matthew; MacDonald, Tobey J (2015). EphrinB1 expression is dysregulated and promotes oncogenic signaling in medulloblastoma. Journal of Neuro-Oncology, 121(1):109-118.
Kros, J M; Huizer, K; Hernandez-Lain, A; Marucci, G; Michotte, A; Pollo, B; Rushing, E J; Ribalta, T; French, P; Jamine, D; Bekka, N; Lacombe, D; van den Bent, M J; Gorlia, T (2015). Evidence-based diagnostic algorithm for glioma: analysis of the results of pathology panel review and molecular parameters of EORTC 26951 and 26882 trials. Journal of Clinical Oncology, 33(17):1943-1950.
Vanlandewijck, Michael; Lebouvier, Thibaud; Andaloussi Mäe, Maarja; Nahar, Khayrun; Hornemann, Simone; Kenkel, David; Cunha, Sara I; Lennartsson, Johan; Boss, Andreas; Heldin, Carl-Henrik; Keller, Annika; Betsholtz, Christer (2015). Functional characterization of germline mutations in PDGFB and PDGFRB in primary familial brain calcification. PLoS ONE, 10(11):e0143407.
Reimann, Regina. Magnetic Resonance Imaging in the Assessment of Anti Prion Mediated Neurotoxicity In Vivo. 2015, University of Zurich, Faculty of Medicine.
Böge, Yannick Thimotheus. Mechanisms of Apoptosis-driven Carcinogenesis and Caspase 8-dependent DNA Damage Response. 2015, University of Zurich, Faculty of Medicine.
Herrmann, Uli S. Mechanisms underlying prion protein toxicity and therapeutic strategies. 2015, University of Zurich, Faculty of Medicine.
Gelpi, Ellen; Colom-Cadena, Marti; Budka, Herbert (2015). Molecular genetics of Creutzfeldt-Jakob disease and Gerstmann- Sträussler- Scheinker disease. Chichester: Wiley.
Dametto, Paolo; Lakkaraju, Asvin K K; Bridel, Claire; Villiger, Lukas; O'Connor, Tracy; Herrmann, Uli S; Pelczar, Pawel; Rülicke, Thomas; McHugh, Donal; Adili, Arlind; Aguzzi, Adriano (2015). Neurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrP. PLoS ONE, 10(2):e0117412.
Stenzel, W; Preusse, C; Allenbach, Y; Pehl, D; Junckerstorff, R; Heppner, F L; Nolte, K; Aronica, E; Kana, V; Rushing, E; Schneider, U; Claeys, K G; Benveniste, O; Weis, J; Goebel, H H (2015). Nuclear actin aggregation is a hallmark of anti-synthetase syndrome-induced dysimmune myopathy. Neurology, 84(13):1346-1354.
Martínez, Javier; Sánchez, Rosa; Castellanos, Milagros; Makarava, Natallia; Aguzzi, Adriano; Baskakov, Ilia V; Gasset, María (2015). PrP charge structure encodes interdomain interactions. Scientific Reports, 5:13623.
Herrmann, Uli S; Sonati, Tiziana; Falsig, Jeppe; Reimann, Regina R; Dametto, Paolo; O'Connor, Tracy; Li, Bei; Lau, Agnes; Hornemann, Simone; Sorce, Silvia; Wagner, Uli; Sanoudou, Despina; Aguzzi, Adriano (2015). Prion infections and anti-PrP antibodies trigger converging neurotoxic pathways. PLoS Pathogens, 11(2):e1004662.
Nuvolone, Mario; Sorce, Silvia; Schwarz, Petra; Aguzzi, Adriano (2015). Prion pathogenesis in the absence of NLRP3/ASC inflammasomes. PLoS ONE, 10(2):e0117208.
Aboulenein-Djamshidian, Fahmy; Höftberger, Romana; Waters, Patrick; Krampla, Wolfgang; Lassmann, Hans; Budka, Herbert; Vincent, Angela; Kristoferitsch, Wolfgang (2015). Reduction in serum aquaporin-4 antibody titers during development of a tumor-like brain lesion in a patient with neuromyelitis optica. Journal of Neuropathology and Experimental Neurology, 74(3):194-197.
Rushing, Elisabeth J; Wesseling, Pieter (2015). Towards an integrated morphological and molecular WHO diagnosis of central nervous system tumors. Current Opinion in Neurology, 28(6):628-632.
Zhu, Caihong; Herrmann, Uli S; Li, Bei; Abakumova, Irina; Moos, Rita; Schwarz, Petra; Rushing, Elisabeth J; Colonna, Marco; Aguzzi, Adriano (2015). Triggering receptor expressed on myeloid cells-2 is involved in prion-induced microglial activation but does not contribute to prion pathogenesis in mouse brains. Neurobiology of Aging, 36(5):1994-2003.
Zhu, Caihong; Schwarz, Petra; Abakumova, Irina; Aguzzi, Adriano (2015). Unaltered prion pathogenesis in a mouse model of high-fat diet-induced insulin resistance. PLoS ONE, 10(12):e0144983.
Varsani, Hemlata; Charman, Susan C; Li, Charles K; Marie, Suely K N; Amato, Anthony A; Banwell, Brenda; Bove, Kevin E; Corse, Andrea M; Emslie-Smith, Alison M; Jacques, Thomas S; Lundberg, Ingrid E; Minetti, Carlo; Nennesmo, Inger; Rushing, Elisabeth J; Sallum, Adriana M E; Sewry, Caroline; Pilkington, Clarissa A; Holton, Janice L; Wedderburn, Lucy R (2015). Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease. Annals of the Rheumatic Diseases, 74(1):204-210.
Rauch, Philipp J; Müllhaupt, Beat; Biedermann, Luc; Manz, Markus G; Ruschitzka, Frank; Flammer, Andreas J; Segerer, Stephan; Mohebbi, Nilufar; Jung, Hans H; Moch, Holger; Ikenberg, Kristian; Aguzzi, Adriano; Nuvolone, Mario; Distler, Oliver; Rauch, Anita; Fehr, Thomas; Gerber, Bernhard (2014). Systemische Amyloidosen. Swiss Medical Forum, 14(50):943-948.
Scharl, M; Bode, B; Rushing, E; Knuth, A; Rordorf, T (2014). Uncommon case of brain metastasis in a patient with a history of heavy smoking. Current Oncology, 21(5):e728-e731.
Aguzzi, Adriano (2014). Neurodegeneration: Alzheimer's disease under strain. Nature, 512(7512):32-34.
Franklin, Bernardo S; Bossaller, Lukas; De Nardo, Dominic; Ratter, Jacqueline M; Stutz, Andrea; Engels, Gudrun; Brenker, Christoph; Nordhoff, Mark; Mirandola, Sandra R; Al-Amoudi, Ashraf; Mangan, Matthew S; Zimmer, Sebastian; Monks, Brian G; Fricke, Martin; Schmidt, Reinhold E; Espevik, Terje; Jones, Bernadette; Jarnicki, Andrew G; Hansbro, Philip M; Busto, Patricia; Marshak-Rothstein, Ann; Hornemann, Simone; Aguzzi, Adriano; Kastenmüller, Wolfgang; Latz, Eicke (2014). The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nature Immunology, 15(8):727-737.
De Bleecker, Jan L; De Paepe, Boel; Aronica, Eleonora; de Visser, Marianne; Amato, Anthony; Aronica, Eleonora; Benveniste, Olivier; De Bleecker, Jan; de Boer, Onno; De Paepe, Boel; de Visser, Marianne; Dimachkie, Mazen; Gherardi, Romain; Goebel, Hans Hilmar; Hilton-Jones, David; Holton, Janice; Lundberg, Ingrid E; Mammen, Andrew; Mastaglia, Frank; Nishino, Ichizo; Rushing, Elisabeth; Daa Schroder, Henrik; Selcen, Duygu; Stenzel, Werner (2014). 205th ENMC International Workshop: Pathology diagnosis of idiopathic inflammatory myopathies Part II 28–30 March 2014, Naarden, The Netherlands. In: 205th ENMC International Workshop: Pathology diagnosis of idiopathic inflammatory myopathies part II 28-30, Naarden, The Netherlands, 28 March 2014 - 30 March 2014. Elsevier, 268-272.
Hermann, Mario; Stillhard, Patrick; Wildner, Hendrik; Seruggia, Davide; Kapp, Viktor; Sánchez-Iranzo, Héctor; Mercader, Nadia; Montoliu, Lluís; Zeilhofer, Hanns Ulrich; Pelczar, Pawel (2014). Binary recombinase systems for high-resolution conditional mutagenesis. Nucleic Acids Research, 42(6):3894-3907.
Neidert, Marian C; Leske, Henning; Matoscevic, Katja; Eisele, Günter; Rushing, Elisabeth; Sürücü, Oguzkan (2014). A 42-year-old male with a new onset generalized seizure. Brain Pathology, 24(1):99-100.
Dametto, Paolo. Characterization of the flexible tail of the prion protein and its mimic shadoo. 2014, University of Zurich, Faculty of Science.
Tonder, Michaela; Rushing, Elisabeth Jane; Grotzer, Michael; Sürücü, Oguzkan; Valavanis, Antonios; Buck, Alfred; Weller, Michael; Roth, Patrick (2014). Clinical reasoning: a 30-year-old woman with recurrent seizures and a cerebral lesion progressing over 2 decades. Neurology, 82(7):e56-e60.
Akiguchi, Ichiro; Shirakashi, Yoshitomo; Budka, Herbert; Watanabe, Yuko; Watanabe, Toshiyuki; Shiino, Akihiko; Ogita, Mihoko; Kawamoto, Yasuhiro; Jungwirth, Susanne; Krampla, Wolfgang; Fischer, Peter (2014). Disproportionate subarachnoid space hydrocephalus-outcome and perivascular space. Annals of Clinical and Translational Neurology, 1(8):562-569.
Läufer, Thorsten. Estrogen dependent premature lethality due to gut dysfunction in a transgenic TDP-43 mouse model. 2014, University of Zurich, Faculty of Science.
Branscheidt, Meret; Frontzek, Karl; Bozinov, Oliver; Valavanis, Anton; Rushing, Elisabeth J; Weller, Michael; Wegener, Susanne (2014). Etoposide/carboplatin chemotherapy for the treatment of metastatic myxomatous cerebral aneurysms. Journal of Neurology, 261(4):828-830.
Ballmer, Boris. Fluorescence resonance energy transfer assays in prion biology. 2014, University of Zurich, Faculty of Science.
Aguzzi, Adriano; Kranich, Jan; Krautler, Nike Julia (2014). Follicular dendritic cells: origin, phenotype, and function in health and disease. Trends in Immunology, 35(3):105-113.
Smith, Alice Boyd; Horkanyne-Szakaly, Iren; Schroeder, Jason W; Rushing, Elisabeth J (2014). From the radiologic pathology archives: Mass lesions of the dura: beyond meningioma—radiologic-pathologic correlation. Radiographics, 34(2):295-312.
Louis, David N; Perry, Arie; Burger, Peter; Ellison, David W; Reifenberger, Guido; von Deimling, Andreas; Aldape, Kenneth; Brat, Daniel; Collins, V Peter; Eberhart, Charles; Figarella-Branger, Dominique; Fuller, Gregory N; Giangaspero, Felice; Giannini, Caterina; Hawkins, Cynthia; Kleihues, Paul; Korshunov, Andrey; Kros, Johan M; Beatriz Lopes, M; Ng, Ho-Keung; Ohgaki, Hiroko; Paulus, Werner; Pietsch, Torsten; Rosenblum, Marc; Rushing, Elisabeth; Soylemezoglu, Figen; Wiestler, Otmar; Wesseling, Pieter (2014). International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading. Brain Pathology, 24(5):429-435.
Kovacs, Gabor G; Breydo, Leonid; Green, Ryan; Kis, Viktor; Puska, Gina; Lőrincz, Péter; Perju-Dumbrava, Laura; Giera, Regina; Pirker, Walter; Lutz, Mirjam; Lachmann, Ingolf; Budka, Herbert; Uversky, Vladimir N; Molnár, Kinga; László, Lajos (2014). Intracellular processing of disease-associated α-synuclein in the human brain suggests prion-like cell-to-cell spread. Neurobiology of Disease, 69:76-92.
Frontzek, Karl; Fluri, Felix; Siemerkus, Jakob; Müller, Beat; Gass, Achim; Christ-Crain, Mirjam; Katan, Mira (2014). Isolated insular strokes and plasma MR-proANP levels are associated with newly diagnosed atrial fibrillation: A pilot study. PLoS ONE, 9(3):e92421.
Akiguchi, Ichiro; Budka, Herbert; Shirakashi, Yoshitomo; Woehrer, Adelheid; Watanabe, Toshiyuki; Shiino, Akihiko; Yamamoto, Yasumasa; Kawamoto, Yasuhiro; Krampla, Wolfgang; Jungwirth, Susanne; Fischer, Peter (2014). MRI features of Binswanger's disease predict prognosis and associated pathology. Annals of Clinical and Translational Neurology, 1(10):813-821.
Palladini, G; Milani, P; Foli, A; Vidus Rosin, M; Basset, M; Lavatelli, F; Nuvolone, M; Obici, L; Perlini, S; Merlini, G (2014). Melphalan and dexamethasone with or without bortezomib in newly diagnosed AL amyloidosis: A matched case–control study on 174 patients. Leukemia, 28(12):2311-2316.
Hofer, Silvia; Rushing, Elisabeth; Preusser, Matthias; Marosi, Christine (2014). Molecular biology of high grade gliomas: what should the clinician know? Chinese Journal of Cancer, 33(1):4-7.
Rushing, Elisabeth; Kellenberger, Christian; Kana, Veronika; Klein, Andrea (2014). Muscle magnetic resonance imaging of the lower limbs: Valuable diagnostic tool in the investigation of childhood neuromuscular disorders. Neuropediatrics, 45(5):278-288.
Martin, Florence; Kana, Veronika; Mori, Andrea Capone; Fischer, Dirk; Parkin, Nicolas; Boltshauser, Eugen; Rushing, Elisabeth Jane; Klein, Andrea (2014). Neurofibromatosis type 1 (NF1) with an unusually severe phenotype due to digeny for NF1 and ryanodine receptor 1 associated myopathy. European Journal of Pediatrics, 173(12):1691-1694.
Hermann, Mario. Novel techniques for high precision genome engineering. 2014, University of Zurich, Faculty of Science.
Palladini, G; Milani, P; Foli, A; Obici, L; Lavatelli, F; Nuvolone, M; Caccialanza, R; Perlini, S; Merlini, G (2014). Oral melphalan and dexamethasone grants extended survival with minimal toxicity in AL amyloidosis: Long-term results of a risk-adapted approach. Haematologica, 99(4):743-750.
Kurt, Timothy D; Bett, Cyrus; Fernández-Borges, Natalia; Joshi-Barr, Shivanjali; Hornemann, Simone; Rülicke, Thomas; Castilla, Joaquín; Wüthrich, Kurt; Aguzzi, Adriano; Sigurdson, Christina J (2014). Prion transmission prevented by modifying the β2-α2 loop structure of host PrPC. Journal of Neuroscience, 34(3):1022-1027.
Bahi, Amine; Chandrasekar, Vijay; Dreyer, Jean-Luc (2014). Selective lentiviral-mediated suppression of microRNA124a in the hippocampus evokes antidepressants-like effects in rats. Psychoneuroendocrinology, 46:78-87.
Ganzinger, Kristina A; Narayan, Priyanka; Qamar, Seema S; Weimann, Laura; Ranasinghe, Rohan T; Aguzzi, Adriano; Dobson, Christopher M; McColl, James; et al (2014). Single-molecule imaging reveals that small Amyloid-β1-42Oligomers interact with the Cellular Prion Protein (PrPC). Chembiochem, 15(17):2515-2521.
Baral, Pravas Kumar; Swayampakula, Mridula; Rout, Manoj Kumar; Kav, Nat N V; Spyracopoulos, Leo; Aguzzi, Adriano; James, Michael N G (2014). Structural basis of prion inhibition by phenothiazine compounds. Structure, 22(2):291-303.
Kusne, Y; Carrera-Silva, E A; Perry, A S; Rushing, E J; Mandell, E K; Dietrich, J D; Errasti, A E; Gibbs, D; Berens, M E; Loftus, J C; Hulme, C; Yang, W; Lu, Z; Aldape, K; Sanai, N; Rothlin, C V; Ghosh, S (2014). Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNF in glioblastoma. Science Signaling, 7(338):ra75.
Yaldizli, Ozgür; Penner, Iris-Katharina; Frontzek, Karl; Naegelin, Yvonne; Amann, Michael; Papadopoulou, Athina; Sprenger, Till; Kuhle, Jens; Calabrese, Pasquale; Radü, Ernst Wilhelm; Kappos, Ludwig; Gass, Achim (2014). The relationship between total and regional corpus callosum atrophy, cognitive impairment and fatigue in multiple sclerosis patients. Multiple Sclerosis, 20(3):356-364.
Sorce, Silvia; Nuvolone, Mario; Keller, Annika; Falsig, Jeppe; Varol, Ahmet; Schwarz, Petra; Bieri, Monika; Budka, Herbert; Aguzzi, Adriano (2014). The role of the NADPH oxidase NOX2 in prion pathogenesis. PLoS Pathogens, 10(12):e1004531.
Scaravilli, Francesco; Hale, Martin; Budka, Herbert (2013). ISN Information Days at the University of Witwatersrand Medical School, Johannesburg (South Africa) on September 23(rd) -24(th) , 2013. In: Fourth Information Days on Neuropathology, Johannesburg, 23 September 2013 - 24 September 2013. Wiley-Blackwell, i-ii.
Rushing, Elisabeth J (2013). Muscle Involvement in Connective Tissue Disorders: Polyarteritis, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Systemic Sclerosis, and Sjögren Syndrome. In: Goebel, Hans H; Sewry, Caroline A; Weller, Roy O. Muscle Disease: Pathology and Genetics. New York: Wiley-Blackwell, 313-315.
Foit, N A; Neidert, M C; Woernle, C M; Rushing, Elisabeth J; Krayenbühl, Niklaus (2013). Bifocal extra- and intradural melanocytoma of the spine: case report and literature review. European Spine Journal, 22(Suppl 3):521-525.
Zeilhofer, Ulrike B; Scheer, Ianina; Warmuth-Metz, Monika; Rushing, Elisabeth J; Pietsch, Torsten; Boltshauser, Eugen; Grotzer, Michael A; Gerber, Nicolas U (2013). Natural history of a medulloblastoma: 30 months of wait and see in a child with a cerebellar incidentaloma. Child's Nervous System, 29(7):1207-1210.
Budka, Herbert (2013). Neuropathology. In: Runehov, Anne; Oviedo, Lluis. Encyclopedia of Sciences and Religions. Dordrecht: Springer, 777.
Budka, H; Kovacs, G G (2013). Gerstmann–Sträussler–Scheinker Disease. In: Maloy, Stanley; Hughes, Kelly. Brenner's Encyclopedia of Genetics, 2nd Edition. New York: Elsevier B.V., 327-329.
Magagna-Poveda, Alejandra; Frontzek, Karl; Bode-Lesniewska, Beata; Rushing, Elisabeth J (2013). A 59-year-old woman with a retroauricular tumor. Brain Pathology, 23(5):603-604.
Wernhart, S; Woernle, C M; Neidert, M C; Bode, B; Rushing, E J; Studer, G; Fuchs, I; Regli, L; Sürücü, O (2013). A deeply seated brain metastasis from a primary myxofibrosarcoma: Case report. Clinical Neurology and Neurosurgery, 115(10):2296-2298.
Aguzzi, Adriano; Gitler, Aaron D (2013). A template for new drugs against Alzheimer's Disease. Cell, 154(6):1182-1184.
Hütt-Cabezas, Marianne; Karajannis, Matthias A; Zagzag, David; Shah, Smit; Horkayne-Szakaly, Iren; Rushing, Elisabeth J; Cameron, J Douglas; Jain, Deepali; Eberhart, Charles G; Raabe, Eric H; Rodriguez, Fausto J (2013). Activation of mTORC1/mTORC2 signaling in pediatric low-grade glioma and pilocytic astrocytoma reveals mTOR as a therapeutic target. Neuro-Oncology, 15(12):1604-1614.
Margalith, Ilan. Anti-prion effect of polythiophenes. 2013, University of Zurich, Faculty of Science.
Krasemann, Susanne; Mearini, Giulia; Krämer, Elisabeth; Wagenführ, Katja; Schulz-Schaeffer, Walter; Neumann, Melanie; Bodemer, Walter; Kaup, Franz-Josef; Beekes, Michael; Carrier, Lucie; Aguzzi, Adriano; Glatzel, Markus (2013). BSE-associated prion-amyloid cardiomyopathy in primates. Emerging Infectious Diseases, 19(6):985-988.
Bellut, D; Holzmann, D; de Alba Buenrostro, G; Rushing, E J; Bernays, R L (2013). CSF containing cystic lesion of the clivus-case report and review of the literature. Clinical Neurology and Neurosurgery, 115(1):95-98.
Ehling, Rainer; Nosková, Lenka; Stránecký, Viktor; Hartmannová, Hana; Přistoupilová, Anna; Hodaňová, Kateřina; Benke, Thomas; Kovacs, Gabor G; Ströbel, Thomas; Niedermüller, Ulrike; Wagner, Michaela; Nachbauer, Wolfgang; Janecke, Andreas; Budka, Herbert; Boesch, Sylvia; Kmoch, Stanislav (2013). Cerebellar dysfunction in a family harboring the PSEN1 mutation co-segregating with a Cathepsin D variant p.A58V. Journal of the Neurological Sciences, 326(1-2):75-82.
Manoli, Irini; Kwan, Justin Y; Wang, Qian; Rushing, Elisabeth J; Tsokos, Maria; Arai, Andrew E; Burch, Warner M; Dispenzieri, Angela; McPherron, Alexandra C; Gahl, William A (2013). Chronic myopathy due to immunoglobulin light chain amyloidosis. Molecular Genetics and Metabolism, 108(4):249-254.
Sanchez-Macedo, N; Feng, J; Faubert, B; Chang, N; Elia, A; Rushing, E J; Tsuchihara, K; Bungard, D; Berger, S L; Jones, R G; Mak, T W; Zaugg, K (2013). Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model. Cell Death and Differentiation, 20(4):659-668.
Sponarova, Jana; Nuvolone, Mario; Whicher, Charlotte; Frei, Nathalie; Kana, Veronika; Schwarz, Petra; Westermark, Gunilla T; Aguzzi, Adriano (2013). Efficient amyloid a clearance in the absence of immunoglobulins and complement factors. American Journal of Pathology, 182(4):1297-1307.
Wanschitz, Julia V; Dubourg, Odile; Lacene, Emmanuelle; Fischer, Michael B; Höftberger, Romana; Budka, Herbert; Romero, Norma B; Eymard, Bruno; Herson, Serge; Butler-Browne, Gillian S; Voit, Thomas; Benveniste, Olivier (2013). Expression of myogenic regulatory factors and myo-endothelial remodeling in sporadic inclusion body myositis. Neuromuscular Disorders : NMD, 23(1):75-83.
Magagna-Poveda, A; Leske, H; Schmid, C; Bernays, R; Rushing, E (2013). Expression of somatostatin receptors, angiogenesis and proliferation markers in pituitary adenomas: an immunohistochemical study with diagnostic and therapeutic implications. Swiss Medical Weekly, 143:w13895.
Deuster, Patricia A; Contreras-Sesvold, Carmen L; O'Connor, Francis G; Campbell, William W; Kenney, Kimbra; Capacchione, John F; Landau, Mark E; Muldoon, Sheila M; Rushing, Elisabeth J; Heled, Yuval (2013). Genetic polymorphisms associated with exertional rhabdomyolysis. European Journal of Applied Physiology, 113(8):1997-2004.
Ahmed, Zeshan; Bigio, Eileen H; Budka, Herbert; Dickson, Dennis W; Ferrer, Isidro; Ghetti, Bernardino; Giaccone, Giorgio; Hatanpaa, Kimmo J; Holton, Janice L; Josephs, Keith A; Powers, James; Spina, Salvatore; Takahashi, Hitoshi; White III, Charles L; Revesz, Tamas; Kovacs, Gabor G (2013). Globular glial tauopathies (GGT): consensus recommendations. Acta Neuropathologica, 126(4):537-544.
Deubelbeiss, A N; Trachsel, C; Bachli, E B; Kuffer, A; Budka, H; Eniseyskiy, P; Zimmermann, H; Wallace, R M; Farley, S; Zanoni, R G (2013). Imported human rabies in Switzerland, 2012: a diagnostic conundrum. Journal of Clinical Virology, 57(2):178-181.
Klug, Genevieve M J A; Wand, Handan; Simpson, Marion; Boyd, Alison; Law, Matthew; Masters, Colin L; Matej, Radoslav; Howley, Rachel; Farrell, Michael; Breithaupt, Maren; Zerr, Inga; van Duijn, Cornelia; Ibrahim-Verbaas, Carla; Mackenzie, Jan; Will, Robert G; Brandel, Jean-Philippe; Alperovitch, Annick; Budka, Herbert; Kovacs, Gabor G; Jansen, Gerard H; Coulthard, Michael; Collins, Steven J (2013). Intensity of human prion disease surveillance predicts observed disease incidence. Journal of Neurology, Neurosurgery, and Psychiatry, 84(12):1372-1377.
Schippling, S; Kempf, C; Büchele, F; Jelcic, I; Bozinov, O; Bont, A; Linnebank, M; Sospedra, M; Weller, M; Budka, H; Martin, R (2013). JCV granule cell neuronopathy and GCN-IRIS under natalizumab treatment. Annals of Neurology, 74(4):622-626.
Aguzzi, Adriano; Barres, Ben A; Bennett, Mariko L (2013). Microglia: scapegoat, saboteur, or something else? Science, 339(6116):156-161.
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Donofrio, G; Heppner, F L; Polymenidou, M; Musahl, C; Aguzzi, A (2005). Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies. Journal of Virology, 79(13):8330-8338.
Glatzel, M; Mohajeri, M H; Poirier, R; Nitsch, R M; Schwarz, Petra; Lu, B; Aguzzi, A (2005). No influence of amyloid-beta-degrading neprilysin activity on prion pathogenesis. Journal of General Virology, 8(6):1861-1867.
Radovanovic, I; Braun, N; Giger, O T; Mertz, K; Miele, G; Prinz, M; Navarro, B; Aguzzi, A (2005). Truncated prion protein and Doppel are myelinotoxic in the absence of oligodendrocytic PrPC. Journal of Neuroscience, 25(19):4879-4888.
Ladogana, A; Puopolo, M; Croes, E A; Budka, H; Jarius, C; Collins, S; Klug, G M; Sutcliffe, T; Giulivi, A; Alperovitch, A; Delasnerie-Laupretre, N; Brandel, J-P; Poser, S; Kretzschmar, H; Rietveld, I; Mitrova, E; de Pedro Cuesta, J; Martinez-Martin, P; Glatzel, M; Aguzzi, A; Knight, R; Ward, H; Pocchiari, M; van Duijn, C M; Will, R G; Zerr, I (2005). Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada. Neurology, 64(9):1586-1591.
Frappart, P O; Tong, W M; Demuth, I; Radovanovic, I; Herceg, Z; Aguzzi, A; Digweed, M; Wang, Z Q (2005). An essential function for NBS1 in the prevention of ataxia and cerebellar defects. Nature Medicine, 11(5):538-544.
Huber, C; Thielen, C; Seeger, H; Schwarz, Petra; Montrasio, F; Wilson, M R; Heinen, E; Fu, Yang-Xin; Miele, G; Aguzzi, A (2005). Lymphotoxin-beta receptor-dependent genes in lymph node and follicular dendritic cell transcriptomes. Journal of Immunology, 174(9):5526-5536.
Nikles, D; Bach, P; Boller, K; Merten, C A; Montrasio, F; Heppner, F L; Aguzzi, A; Cichutek, K; Kalinke, U; Buchholz, C J (2005). Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP. Journal of Virology, 79(7):4033-4042.
Glatzel, M; Stoeck, K; Seeger, H; Lührs, T; Aguzzi, A (2005). Human prion diseases: molecular and clinical aspects. Archives of Neurology, 62(4):545-552.
Russmann, H; Vingerhoets, F; Miklossy, J; Maeder, P; Glatzel, M; Aguzzi, A; Bogousslavsky, J (2005). Sporadic Creutzfeldt-Jakob disease: a comparison of pathological findings and diffusion weighted imaging. Journal of Neurology, 252(3):338-342.
Uelhoff, A; Tatzelt, J; Aguzzi, A; Winklhofer, K F; Haass, C (2005). A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein. Journal of Biological Chemistry, 280(7):5137-5140.
Heikenwalder, M; Zeller, N; Seeger, H; Prinz, M; Klöhn, P C; Schwarz, Petra; Ruddle, N H; Weissmann, Charles; Aguzzi, A (2005). Chronic lymphocytic inflammation specifies the organ tropism of prions. Science, 307(5712):1107-1110.
Masel, J; Genoud, Nicolas; Aguzzi, A (2005). Efficient inhibition of prion replication by PrP-Fc(2) suggests that the prion is a PrP(Sc) oligomer. Journal of Molecular Biology, 345(5):1243-1251.
Heppner, F L; Greter, M; Marino, D; Falsig, J; Raivich, G; Hövelmeyer, N; Waisman, A; Rülicke, T; Prinz, M; Priller, J; Becher, B; Aguzzi, A (2005). Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nature Medicine, 11(2):146-152.
Steinacker, P; Schwarz, P; Reim, K; Brechlin, P; Jahn, O; Kratzin, H; Aitken, A; Wiltfang, J; Aguzzi, A; Bahn, E; Baxter, H C; Brose, Nils; Otto, M (2005). Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein. Molecular and Cellular Biology, 25(4):1339-1346.
Weissmann, Charles; Aguzzi, A (2005). Approaches to therapy of prion diseases. Annual Review of Medicine, 56:321-344.
Aguzzi, A (2005). Cell biology. Prion toxicity: all sail and no anchor. Science, 308(5727):1420-1421.
Sigurdson, Christina; Glatzel, Markus; Aguzzi, Adriano (2005). Comment on "Failure to detect prion protein (PrPres) by immunohistochemistry in striated muscle tissues of animals experimentally inoculated with agents of transmissible spongiform encephalopathy". Veterinary Pathology, 42(1):107.
Ligios, C; Sigurdson, Christina J; Santucciu, C; Carcassola, G; Manco, G; Basagni, M; Maestrale, C; Cancedda, M G; Madau, L; Aguzzi, Adriano (2005). PrPSc in mammary glands of sheep affected by scrapie and mastitis. Nature Medicine, 11(11):1137-1138.
Aguzzi, A; Heikenwalder, M (2005). Prions, cytokines, and chemokines: a meeting in lymphoid organs. Immunity, 22(2):145-154.
Sigurdson, C; Polymenidou, M; Aguzzi, A (2005). Reconstructing prions: fibril assembly from simple yeast to complex mammals. Neurodegenerative Diseases, 2(1):1-5.
Hugel, B; Martínez, M C; Kunzelmann, C; Blättler, T; Aguzzi, A; Freyssinet, J M (2004). Modulation of signal transduction through the cellular prion protein is linked to its incorporation in lipid rafts. Cellular and Molecular Life Sciences, 61(23):2998-3007.
Hornemann, Simone; Schorno, Christian; Wüthrich, Kurt (2004). NMR structure of the bovine prion protein isolated from healthy calf brains. EMBO Reports, 5(12):1159-1164.
Spaeth, N; Wyss, M T; Weber, B; Scheidegger, S; Lutz, A; Verwey, J; Radovanovic, I; Pahnke, J; Wild, D; Westera, G; Weishaupt, D; Hermann, D M; Kaser-Hotz, B; Aguzzi, A; Buck, A (2004). Uptake of 18F-fluorocholine, 18F-fluoroethyl-L-tyrosine, and 18F-FDG in acute cerebral radiation injury in the rat: implications for separation of radiation necrosis from tumor recurrence. Journal of Nuclear Medicine, 45(11):1931-1938.
Polymenidou, M; Heppner, F L; Pellicioli, E C; Urich, E; Miele, G; Braun, N; Wopfner, F; Schätzl, H M; Becher, B; Aguzzi, A (2004). Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 101(S2):14670-14676.
Pocchiari, M; Puopolo, M; Croes, E A; Budka, H; Gelpi, E; Collins, S; Lewis, V; Sutcliffe, T; Guilivi, A; Delasnerie-Laupretre, N; Brandel, J-P; Alperovitch, A; Zerr, I; Poser, S;