Navigation auf zora.uzh.ch
Navigation auf zora.uzh.ch
Calvanese, Anna Laura. Developmental Cues and Function of Tertiary Lymphoid Structures. 2024, University of Zurich, Faculty of Science.
Sparano, Colin. Deciphering the Origin and Function of Tissue-Resident Group 1 Innate Lymphoid Cells. 2024, University of Zurich, Faculty of Science.
Mietz, Juliane. Genetic Engineering of CAR NK Cells and Characterization of an Autologous Humanized Mouse Tumor Model. 2024, University of Zurich, Faculty of Science.
Fan, Zheng; Karakone, Mara; Nagarajan, Shunmugam; Nagy, Nadine; Mildenberger, Wiebke; Petrova, Ekaterina; Hinte, Laura Catharina; Bijnen, Mitchell; Häne, Philipp; Nelius, Eric; Chen, Jing; Ferapontova, Irina; von Meyenn, Ferdinand; Trepiccione, Francesco; Berber, Mesut; Ribas, David Penton; Eichmann, Anne; Zennaro, Maria-Christina; Takeda, Norihiko; Fischer, Jens W; Spyroglou, Ariadni; Reincke, Martin; Beuschlein, Felix; Loffing, Johannes; Greter, Melanie; Stockmann, Christian (2024). Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure. Cell Reports, 43(7):114395.
Kienzler, Jenny Christine. High-Dimensional Flow Cytometry of Tumor and Immune Cell Marker in High Grade Glioma. 2024, University of Zurich, Faculty of Science.
de Arriba, Magdalena; Borel, Nicole; LeibundGut-Landmann, Salomé (2024). Water-filtered infrared A irradiation exerts antifungal effects on the skin fungus Malassezia. Journal of Photochemistry and Photobiology B: Biology, 255:112909.
Schuhmachers, Patrick. A Call to the Arms: Regulation of T Cell Responses during EBV Infection and T Cell-Directed Immunotherapy of EBV-Associated Lymphomas. 2024, University of Zurich, Faculty of Science.
Schmidt, Katarina Wendy. Autophagy Proteins in the Restriction of Kaposi Sarcoma-Associated Herpesvirus Entry. 2024, University of Zurich, Faculty of Science.
Lütge, Mechthild. The Origin and Molecular Identity of Immune-Interacting Reticular Cells in Secondary Lymphoid Organs. 2024, University of Zurich, Faculty of Science.
Gramalla-Schmitz, Anna. The Role of Cellular Gene Editors during γ-Herpesvirus Infections and Associated B-Cell Lymphomagenesis. 2024, University of Zurich, Faculty of Science.
Westermann, Frederike. A Non-Classical Ontogenetic Path Gives Rise to a GM-CSF Dependent Macrophage Population in the Developing Salivary Gland. 2024, University of Zurich, Faculty of Science.
Petrova, Ekaterina. Deciphering the Role of Border-Associated Macrophages in Glioblastoma Development by Using Novel CD206-Transgenic Mouse Models. 2024, University of Zurich, Faculty of Science.
Rieble, Lisa. Gammaherpesvirus-Induced T Cell-Mediated Immune Control and Tumorigenesis in a Model of Dual-Infection. 2024, University of Zurich, Faculty of Science.
Grabherr, Sarah. Spatial – Temporal Control of Inhaled Murine Coronavirus Infection. 2024, University of Zurich, Faculty of Science.
Roth, Lilian. Exploring Mechanisms behind Beneficial Effects of HIPEC Treatment on Peritoneal Metastasis. 2024, University of Zurich, Faculty of Science.
Callegari, Ilaria; Oechtering, Johanna; Schneider, Mika; Perriot, Sylvain; Mathias, Amandine; Voortman, Margarete M; Cagol, Alessandro; Lanner, Ulrike; Diebold, Martin; Holdermann, Sebastian; Kreiner, Victor; Becher, Burkhard; Granziera, Cristina; Junker, Andreas; Du Pasquier, Renaud; Khalil, Michael; Kuhle, Jens; Kappos, Ludwig; Sanderson, Nicholas S R; Derfuss, Tobias (2024). Cell-binding IgM in CSF is distinctive of multiple sclerosis and targets the iron transporter SCARA5. Brain: a journal of neurology, 147(3):839-848.
Al Hrout, Alaa. B Cells EV-Mediated Signaling in Melanoma. 2024, University of Zurich, Faculty of Science.
Münz, Christian (2024). Immune control of human γ-herpes infections. Seminars in Arthritis and Rheumatism, 64:152320.
Kienzler, Jenny C; Becher, Burkhard (2024). Immunity in malignant brain tumors: Tumor entities, role of immunotherapy, and specific contribution of myeloid cells to the brain tumor microenvironment. European Journal of Immunology, 54(2):2250257.
Weischedel, Julian; Higgins, Laurence; Rogers, Sally; Gramalla-Schmitz, Anna; Wyrzykowska, Paulina; Borgoni, Simone; MacCarthy, Thomas; Chahwan, Richard (2024). Modular cytosine base editing promotes epigenomic and genomic modifications. Nucleic Acids Research, 52(2):e8.
Ulutekin, Can; Galli, Edoardo; Schreiner, Bettina; Khademi, Mohsen; Callegari, Ilaria; Piehl, Fredrik; Sanderson, Nicholas; Kirschenbaum, Daniel; Mundt, Sarah; Filippi, Massimo; Furlan, Roberto; Olsson, Tomas; Derfuss, Tobias; Ingelfinger, Florian; Becher, Burkhard (2024). B cell depletion attenuates CD27 signaling of T helper cells in multiple sclerosis. Cell Reports Medicine, 5(1):101351.
Ruchti, Fiorella; Tuor, Meret; Mathew, Liya; McCarthy, Neil E; LeibundGut-Landmann, Salomé (2024). γδ T cells respond directly and selectively to the skin commensal yeast Malassezia for IL-17-dependent fungal control. PLoS Pathogens, 20(1):e1011668.
Maas-Bauer, Kristina; Stell, Anna-Verena; Yan, Kai-Li; de Vega, Enrique; Vinnakota, Janaki Manoja; Unger, Susanne; Núñez, Nicolás; Norona, Johana; Talvard-Balland, Nana; Koßmann, Stefanie; Schwan, Carsten; Miething, Cornelius; Martens, Uta S; Shoumariyeh, Khalid; Nestor, Rosa P; Duquesne, Sandra; Hanke, Kathrin; Rackiewicz, Michal; Hu, Zehan; El Khawanky, Nadia; Taromi, Sanaz; Andrlova, Hana; Faraidun, Hemin; Walter, Stefanie; Pfeifer, Dietmar; Follo, Marie; Waldschmidt, Johannes; Melchinger, Wolfgang; Rassner, Michael; Wehr, Claudia; et al (2024). ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature Communications, 15(1):446.
van Rijthoven, Mart; Obahor, Simon; Pagliarulo, Fabio; van den Broek, Maries; Schraml, Peter; Moch, Holger; van der Laak, Jeroen; Ciompi, Francesco; Silina, Karina (2024). Multi-resolution deep learning characterizes tertiary lymphoid structures and their prognostic relevance in solid tumors. Communications Medicine, 4(1):5.
Kosmala, Daria; Sertour, Natacha; Fróis Martins, Ricardo; Spaggiari, Luca; Ardizzoni, Andrea; LeibundGut-Landmann, Salomé; Pericolini, Eva; Bougnoux, Marie-Elisabeth; d’Enfert, Christophe; Legrand, Mélanie (2024). The pathogenic and colonization potential of Candida africana. Microbes and infection, 26(1-2):105230.
Yim, Kevin Ho Wai; Krzyzaniak, Olga; Al Hrout, Ala'a; Peacock, Ben; Chahwan, Richard (2023). Assessing Extracellular Vesicles in Human Biofluids Using Flow‐Based Analyzers. Advanced Healthcare Materials, 12(32):2301706.
Münz, Christian (2023). Modulation of Epstein-Barr-Virus (EBV)-Associated Cancers by Co-Infections. Cancers, 15(24):5739.
Tuor, Meret; LeibundGut-Landmann, Salomé (2023). The skin mycobiome and intermicrobial interactions in the cutaneous niche. Current Opinion in Microbiology, 76:102381.
Bosch, Angela J T; Keller, Lena; Steiger, Laura; Rohm, Theresa V; Wiedemann, Sophia J; Low, Andy J Y; Stawiski, Marc; Rachid, Leila; Roux, Julien; Konrad, Daniel; Wueest, Stephan; Tugues, Sonia; Greter, Melanie; Böni-Schnetzler, Marianne; Meier, Daniel T; Cavelti-Weder, Claudia (2023). CSF1R inhibition with PLX5622 affects multiple immune cell compartments and induces tissue-specific metabolic effects in lean mice. Diabetologia, 66(12):2292-2306.
McKendrick, John G; Jones, Gareth-Rhys; Elder, Sonia S; Watson, Erin; T'Jonck, Wouter; Mercer, Ella; Magalhaes, Marlene S; Rocchi, Cecilia; Hegarty, Lizi M; Johnson, Amanda L; Schneider, Christoph; Becher, Burkhard; Pridans, Clare; Mabbott, Neil; Liu, Zhaoyuan; Ginhoux, Florent; Bajenoff, Marc; Gentek, Rebecca; Bain, Calum C; Emmerson, Elaine (2023). CSF1R-dependent macrophages in the salivary gland are essential for epithelial regeneration after radiation-induced injury. Science Immunology, 8(89):eadd4374.
Apostolova, Petya; Kreutmair, Stefanie; Toffalori, Cristina; Punta, Marco; Unger, Susanne; Burk, Ann‐Cathrin; Wehr, Claudia; Maas‐Bauer, Kristina; Melchinger, Wolfgang; Haring, Eileen; Hoefflin, Rouven; Shoumariyeh, Khalid; Hupfer, Valerie; Lauer, Eliza Maria; Duquesne, Sandra; Lowinus, Theresa; Gonzalo Núñez, Nicolás; Alberti, Chiara; da Costa Pereira, Sara; Merten, Carla Helena; Power, Laura; Weiss, Matthias; Böke, Caroline; Pfeifer, Dietmar; Marks, Reinhard; Bertz, Hartmut; Wäsch, Ralph; Ihorst, Gabriele; Gentner, Bernhard; Duyster, Justus; Boerries, Melanie; Andrieux, Geoffroy; Finke, Juergen; Becher, Burkhard; Vago, Luca; Zeiser, Robert (2023). Phase II trial of hypomethylating agent combined with nivolumab for acute myeloid leukaemia relapse after allogeneic haematopoietic cell transplantation—Immune signature correlates with response. British Journal of Haematology, 203(2):264-281.
Andreadou, Myrto; Ingelfinger, Florian; De Feo, Donatella; Cramer, Teresa L M; Tuzlak, Selma; Friebel, Ekaterina; Schreiner, Bettina; Eede, Pascale; Schneeberger, Shirin; Geesdorf, Maria; Ridder, Frederike; Welsh, Christina A; Power, Laura; Kirschenbaum, Daniel; Tyagarajan, Shiva K; Greter, Melanie; Heppner, Frank L; Mundt, Sarah; Becher, Burkhard (2023). IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice. Nature Neuroscience, 26(10):1701-1712.
Marinović, Sonja; Lenartić, Maja; Mladenić, Karlo; Šestan, Marko; Kavazović, Inga; Benić, Ante; Krapić, Mia; Rindlisbacher, Lukas; Cokarić Brdovčak, Maja; Sparano, Colin; Litscher, Gioana; Turk Wensveen, Tamara; Mikolašević, Ivana; Fučkar Čupić, Dora; Bilić-Zulle, Lidija; Steinle, Aleksander; Waisman, Ari; Hayday, Adrian; Tugues, Sonia; Becher, Burkhard; Polić, Bojan; Wensveen, Felix M (2023). NKG2D-mediated detection of metabolically stressed hepatocytes by innate-like T cells is essential for initiation of NASH and fibrosis. Science Immunology, 8(87):eadd1599.
Silva de Melo, Bruno Marcel; Veras, Flávio Protásio; Zwicky, Pascale; Lima, Diógenes; Ingelfinger, Florian; Martins, Timna Varela; da Silva Prado, Douglas; Schärli, Stefanie; Publio, Gabriel; Hiroki, Carlos Hiroji; Melo, Paulo Henrique; Saraiva, André; Norbiato, Thainá; Lima, Leonardo; Ryffel, Bernhard; Vogl, Thomas; Roth, Johannes; Waisman, Ari; Nakaya, Helder I; da Silva Souza, Cacilda; Cunha, Fernando Q; Cunha, Thiago M; Becher, Burkhard; Alves-Filho, José C (2023). S100A9 Drives the Chronification of Psoriasiform Inflammation by Inducing IL-23/Type 3 Immunity. Journal of Investigative Dermatology, 143(9):1678-1688.e8.
Hiltbrunner, Stefanie; Cords, Lena; Kasser, Sabrina; Freiberger, Sandra N; Kreutzer, Susanne; Toussaint, Nora C; Grob, Linda; Opitz, Isabelle; Messerli, Michael; Zoche, Martin; Soltermann, Alex; Rechsteiner, Markus; van den Broek, Maries; Bodenmiller, Bernd; Curioni-Fontecedro, Alessandra (2023). Acquired resistance to anti-PD1 therapy in patients with NSCLC associates with immunosuppressive T cell phenotype. Nature Communications, 14(1):5154.
Pena-Francesch, Maria; Vanoaica, Liliana Danusia; Zhu, Gao-Feng; Stumpe, Michael; Sankar, Devanarayanan Siva; Nowag, Heike; Valencia-Camargo, Alma Delia; Hammerschmidt, Wolfgang; Dengjel, Jörn; Ligeon, Laure-Anne; Münz, Christian (2023). The autophagy machinery interacts with EBV capsids during viral envelope release. Proceedings of the National Academy of Sciences of the United States of America, 120(34):e2211281120.
Forde, Aaron James; Kolter, Julia; Zwicky, Pascale; Baasch, Sebastian; Lohrmann, Florens; Eckert, Marleen; Gres, Vitka; Lagies, Simon; Gorka, Oliver; Rambold, Angelika S; Buescher, Joerg M; Kammerer, Bernd; Lachmann, Nico; Prinz, Marco; Groß, Olaf; Pearce, Edward J; Becher, Burkhard; Henneke, Philipp (2023). Metabolic rewiring tunes dermal macrophages in staphylococcal skin infection. Science Immunology, 8(86):eadg3517.
Liu, Zhaoyuan; Wang, Haiting; Li, Ziyi; Dress, Regine J; Zhu, Yiwen; Zhang, Shuangyan; De Feo, Donatella; Kong, Wan Ting; Cai, Peiliang; Shin, Amanda; Piot, Cécile; Yu, Jiangyan; Gu, Yaqi; Zhang, Mingnan; Gao, Caixia; Chen, Lei; Wang, Honglin; Vétillard, Mathias; Guermonprez, Pierre; Kwok, Immanuel; Ng, Lai Guan; Chakarov, Svetoslav; Schlitzer, Andreas; Becher, Burkhard; Dutertre, Charles-Antoine; Su, Bing; Ginhoux, Florent (2023). Dendritic cell type 3 arises from Ly6C$^{+}$ monocyte-dendritic cell progenitors. Immunity, 56(8):1761-1777.e6.
Langenbach, Marlene; Giesler, Sophie; Richtsfeld, Stefan; Costa-Pereira, Sara; Rindlisbacher, Lukas; Wertheimer, Tobias; Braun, Lukas M; Andrieux, Geoffroy; Duquesne, Sandra; Pfeifer, Dietmar; Woessner, Nadine M; Menssen, Hans D; Taromi, Sanaz; Duyster, Justus; Börries, Melanie; Brummer, Tilman; Blazar, Bruce R; Minguet, Susana; Turko, Patrick; Levesque, Mitchell P; Becher, Burkhard; Zeiser, Robert (2023). MDM2 Inhibition Enhances Immune Checkpoint Inhibitor Efficacy by Increasing IL15 and MHC Class II Production. Molecular Cancer Research, 21(8):849-864.
Zens, Kyra Denise; Llanas-Cornejo, Daniel; Menges, Dominik; Fehr, Jan Sven; Münz, Christian; Puhan, Milo Alan; Frei, Anja (2023). Longitudinal humoral and cell-mediated immune responses in a population-based cohort in Zurich, Switzerland between March and June 2022 - evidence for protection against Omicron SARS-CoV-2 infection by neutralizing antibodies and spike-specific T-cell responses. International Journal of Infectious Diseases, 133:18-26.
Bonetti, Lynn; Horkova, Veronika; Longworth, Joseph; Guerra, Luana; Kurniawan, Henry; Franchina, Davide G; Soriano-Baguet, Leticia; Grusdat, Melanie; Spath, Sabine; Koncina, Eric; Ewen, Anouk; Binsfeld, Carole; Verschueren, Charlène; Gérardy, Jean-Jacques; Kobayashi, Takumi; Dostert, Catherine; Farinelle, Sophie; Härm, Janika; Chen, Ying; Harris, Isaac S; Lang, Philipp A; Vasiliou, Vasilis; Waisman, Ari; Letellier, Elisabeth; Becher, Burkhard; Mittelbronn, Michel; Brenner, Dirk (2023). A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation. bioRxiv 547932, Cold Spring Harbor Laboratory.
Bosch, Angela J T; Rohm, Theresa V; AlAsfoor, Shefaa; Low, Andy J Y; Baumann, Zora; Parayil, Neena; Noreen, Faiza; Roux, Julien; Meier, Daniel T; Cavelti-Weder, Claudia (2023). Diesel Exhaust Particle (DEP)-induced glucose intolerance is driven by an intestinal innate immune response and NLRP3 activation in mice. Particle and Fibre Toxicology, 20(1):25.
Cansever, Dilay; Petrova, Ekaterina; Krishnarajah, Sinduya; Mussak, Caroline; Welsh, Christina A; Mildenberger, Wiebke; Mulder, Kevin; Kreiner, Victor; Roussel, Elsa; Stifter, Sebastian A; Andreadou, Myrto; Zwicky, Pascale; Jurado, Nicole Puertas; Rehrauer, Hubert; Tan, Ge; Liu, Zhaoyuan; Blériot, Camille; Ronchi, Francesca; Macpherson, Andrew J; Ginhoux, Florent; Natalucci, Giancarlo; Becher, Burkhard; Greter, Melanie (2023). Lactation-associated macrophages exist in murine mammary tissue and human milk. Nature Immunology, 24(7):1098-1109.
Läderach, Fabienne; Zdimerova, Hana; Rieble, Lisa; Schuhmachers, Patrick; Engelmann, Christine; Valencia-Camargo, Alma Delia; Kirchmeier, Daniel; Böni, Michelle; Münz, Christian (2023). MHC class II-deficient mice allow functional human CD4$^{+}$ T-cell development. European Journal of Immunology, 53(7):e2250313.
Nopper, Svenja Luisa; Schmidt, Katarina Wendy; Ligeon, Laure-Anne; Münz, Christian (2023). Analysis of LC3-Associated Phagocytosis and Antigen Presentation in Macrophages and B Cells. In: Botelho, Roberto J. Phagocytosis and phagosomes : methods and protocols (2nd edition). New York: Springer, 311-336.
Freitag, Patrick C; Kaulfuss, Meike; Flühler, Lea; Mietz, Juliane; Weiss, Fabian; Brücher, Dominik; Kolibius, Jonas; Hartmann, K Patricia; Smith, Sheena N; Münz, Christian; Chijioke, Obinna; Plückthun, Andreas (2023). Targeted adenovirus-mediated transduction of human T cells in vitro and in vivo. Molecular Therapy - Methods & Clinical Development, 29:120-132.
Gullotta, Giorgia Serena; De Feo, Donatella; Friebel, Ekaterina; Semerano, Aurora; Scotti, Giulia Maria; Bergamaschi, Andrea; Butti, Erica; Brambilla, Elena; Genchi, Angela; Capotondo, Alessia; Gallizioli, Mattia; Coviello, Simona; Piccoli, Marco; Vigo, Tiziana; Della Valle, Patrizia; Ronchi, Paola; Comi, Giancarlo; D’Angelo, Armando; Maugeri, Norma; Roveri, Luisa; Uccelli, Antonio; Becher, Burkhard; Martino, Gianvito; Bacigaluppi, Marco (2023). Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology. Nature Immunology, 24(6):925-940.
Nuñez, Nicolás Gonzalo; Schmid, Jonas; Power, Laura; Alberti, Chiara; Krishnarajah, Sinduya; Kreutmair, Stefanie; Unger, Susanne; Blanco, Sebastián; Konigheim, Brenda; Marín, Constanza; Onofrio, Luisina; Kienzler, Jenny Christine; Costa-Pereira, Sara; Ingelfinger, Florian; Cerbán, Fabio; Chiapello, Laura; Montes, Carolina; Motrán, Cristina; Dutto, Jeremías; Almada, Laura; Boffelli, Lucía; Spinsanti, Lorena; Díaz, Adrián; Rivarola, María Elisa; Bioq, Javier Aguilar; Beranek, Mauricio; Pasinovich, Marina E; Castelli, Juan M; Vizzotti, Carla; Schaefer, Maximilian; et al; Villar-Vesga, Juan; Mundt, Sarah; Merten, Carla Helena; Sethi, Aakriti; Wertheimer, Tobias; Lutz, Mirjam; Vanoaica, Danusia; Münz, Christian; Becher, Burkhard; et al (2023). High-dimensional analysis of 16 SARS-CoV-2 vaccine combinations reveals lymphocyte signatures correlating with immunogenicity. Nature Immunology, 24(6):941-954.
Lysenko, Veronika; Schürch, Patrick M; Tuzlak, Selma; van Wijk, Nicole Wildner-Verhey; Kovtonyuk, Larisa V; Becher, Burkhard; Manz, Markus G; Kreutmair, Stefanie; Theocharides, Alexandre P A (2023). Blocking the CD47-SIRPα interaction reverses the disease phenotype in a polycythemia vera mouse model. Leukemia, 37(6):1277-1286.
Al Hrout, Ala’a; Levesque, Mitchell P; Chahwan, Richard (2023). Investigating the tumor-immune microenvironment through extracellular vesicles from frozen patient biopsies and 3D cultures. Frontiers in Immunology, 14:1176175.
Look, Thomas; Puca, Emanuele; Bühler, Marcel; Kirschenbaum, Daniel; De Luca, Roberto; Stucchi, Riccardo; Ravazza, Domenico; Di Nitto, Cesare; Roth, Patrick; Katzenelenbogen, Yonatan; Weiner, Assaf; Rindlisbacher, Lukas; Becher, Burkhard; Amit, Ido; Weller, Michael; Neri, Dario; Hemmerle, Teresa; Weiss, Tobias (2023). Targeted delivery of tumor necrosis factor in combination with CCNU induces a T cell-dependent regression of glioblastoma. Science Translational Medicine, 15(697):eadf2281.
Thomas, Olivia G; Bronge, Mattias; Tengvall, Katarina; Akpinar, Birce; Nilsson, Ola B; Holmgren, Erik; Hessa, Tara; Gafvelin, Guro; Khademi, Mohsen; Alfredsson, Lars; Martin, Roland; Guerreiro-Cacais, André Ortlieb; Grönlund, Hans; Olsson, Tomas; Kockum, Ingrid (2023). Cross-reactive EBNA1 immunity targets alpha-crystallin B and is associated with multiple sclerosis. Science Advances, 9(20):eadg3032.
Saikumar Lakshmi, Priya; Oduor, Cliff I; Forconi, Catherine S; M'Bana, Viriato; Bly, Courtney; Gerstein, Rachel M; Otieno, Juliana A; Ong'echa, John M; Münz, Christian; Luftig, Micah A; Brehm, Michael A; Bailey, Jeffrey A; Moormann, Ann M (2023). Endemic Burkitt lymphoma avatar mouse models for exploring inter-patient tumor variation and testing targeted therapies. Life Science Alliance, 6(5):e202101355.
Oluoch, Peter O; Forconi, Catherine S; Oduor, Cliff I; Ritacco, Dominic A; Akala, Hoseah M; Bailey, Jeffrey A; Juliano, Jonathan J; Ong'echa, John M; Münz, Christian; Moormann, Ann M (2023). Distinctive Kaposi Sarcoma-Associated Herpesvirus Serological Profile during Acute Plasmodium falciparum Malaria Episodes. International Journal of Molecular Sciences, 24(7):6711.
Abeliovich, Hagai; Debnath, Jayanta; Ding, Wen-Xing; Jackson, William T; Kim, Do-Hyung; Klionsky, Daniel J; Ktistakis, Nicholas; Margeta, Marta; Münz, Christian; Petersen, Morten; Sadoshima, Junichi; Vergne, Isabelle (2023). Where is the field of autophagy research heading? Autophagy, 19(4):1049-1054.
Paust, Hans-Joachim; Song, Ning; De Feo, Donatella; Asada, Nariaki; Tuzlak, Selma; Zhao, Yu; Riedel, Jan-Hendrik; Hellmig, Malte; Sivayoganathan, Amirrtavarshni; Peters, Anett; Kaffke, Anna; Borchers, Alina; Wenzel, Ulrich O; Steinmetz, Oliver M; Tiegs, Gisa; Meister, Elisabeth; Mack, Matthias; Kurts, Christian; von Vietinghoff, Sibylle; Lindenmeyer, Maja T; Hoxha, Elion; Stahl, Rolf A K; Huber, Tobias B; Bonn, Stefan; Meyer-Schwesinger, Catherine; Wiech, Thorsten; Turner, Jan-Eric; Becher, Burkhard; Krebs, Christian F; Panzer, Ulf (2023). CD4+ T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12. Science Translational Medicine, 15(687):eadd6137.
Gurtner, Alessandra; Borrelli, Costanza; Gonzalez-Perez, Ignacio; Bach, Karsten; Acar, Ilhan E; Núñez, Nicolás G; Crepaz, Daniel; Handler, Kristina; Vu, Vivian P; Lafzi, Atefeh; Stirm, Kristin; Raju, Deeksha; Gschwend, Julia; Basler, Konrad; Schneider, Christoph; Slack, Emma; Valenta, Tomas; Becher, Burkhard; Krebs, Philippe; Moor, Andreas E; Arnold, Isabelle C (2023). Active eosinophils regulate host defense and immune responses in colitis. Nature, 615(7950):151-157.
Locatelli, Giuseppe; Marques‐Ferreira, Filipa; Katsoulas, Antonis; Kalaitzaki, Vasileia; Krueger, Martin; Ingold‐Heppner, Barbara; Walthert, Sabrina; Sankowski, Roman; Prazeres da Costa, Olivia; Dolga, Amalia; Huber, Magdalena; Gold, Maike; Culmsee, Carsten; Waisman, Ari; Bechmann, Ingo; Milchevskaya, Vladislava; Prinz, Marco; Tresch, Achim; Becher, Burkhard; Buch, Thorsten (2023). IGF1R expression by adult oligodendrocytes is not required in the steady-state but supports neuroinflammation. Glia, 71(3):616-632.
Ingelfinger, Florian; Kramer, Michael; Lutz, Mirjam; Widmer, Corinne C; Piccoli, Luca; Kreutmair, Stefanie; Wertheimer, Tobias; Woodhall, Mark; Waters, Patrick; Sallusto, Federica; Lanzavecchia, Antonio; Mundt, Sarah; Becher, Burkhard; Schreiner, Bettina (2023). Antibodies Produced by CLL Phenotype B Cells in Patients With Myasthenia Gravis Are Not Directed Against Neuromuscular Endplates. Neurology: Neuroimmunology and Neuroinflammation, 10(2):e200087.
Speiser, Daniel E; Chijioke, Obinna; Schaeuble, Karin; Münz, Christian (2023). CD$4^{\text{+}}$ T cells in cancer. Nature Cancer, 4(3):317-329.
Bjornevik, Kjetil; Münz, Christian; Cohen, Jeffrey I; Ascherio, Alberto (2023). Epstein-Barr virus as a leading cause of multiple sclerosis: mechanisms and implications. Nature Reviews. Neurology, 19(3):160-171.
Spalinger, Marianne R; Kasper, Stephanie; Gottier, Claudia; Lang, Silvia; Atrott, Kirstin; Vavricka, Stephan R; Scharl, Sylvie; Gutte, Petrus M; Grütter, Markus G; Beer, Hans-Dietmar; Contassot, Emmanuel; Chan, Andrew C; Dai, Xuezhi; Rawlings, David J; Mair, Florian; Becher, Burkhard; Falk, Werner; Fried, Michael; Rogler, Gerhard; Scharl, Michael (2023). NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22. Journal of Clinical Investigation, 133(4):e169304.
Nuñez, Nicolas Gonzalo; Berner, Fiamma; Friebel, Ekaterina; Unger, Susanne; Wyss, Nina; Gomez, Julia Martinez; Purde, Mette-Triin; Niederer, Rebekka; Porsch, Maximilian; Lichtensteiger, Christa; Kramer, Rafaela; Erdmann, Michael; Schmitt, Christina; Heinzerling, Lucie; Abdou, Marie-Therese; Karbach, Julia; Schadendorf, Dirk; Zimmer, Lisa; Ugurel, Selma; Klümper, Niklas; Hölzel, Michael; Power, Laura; Kreutmair, Stefanie; Capone, Mariaelena; Madonna, Gabriele; Cevhertas, Lacin; Heider, Anja; Amaral, Teresa; Hasan Ali, Omar; Bomze, David; et al (2023). Immune signatures predict development of autoimmune toxicity in patients with cancer treated with immune checkpoint inhibitors. Med, 4(2):113-129.
Lehmann, Julia; Caduff, Nicole; Krzywińska, Ewelina; Stierli, Salome; Salas-Bastos, Adrian; Loos, Benjamin; Levesque, Mitchell P; Dummer, Reinhard; Stockmann, Christian; Münz, Christian; Diener, Johanna; Sommer, Lukas (2023). Escape from NK cell tumor surveillance by NGFR-induced lipid remodeling in melanoma. Science Advances, 9(2):eadc8825.
Münz, Christian (2023). Immune checkpoints in T cells during oncogenic γ-herpesvirus infections. Journal of Medical Virology, 95(1):e27840.
Kirchmeier, Daniel. Human Tissue Resident Memory T Cells upon Epstein-Barr Virus Infection and the Interplay Between EBV Location and Lymphocyte Phenotypes. 2023, University of Zurich, Faculty of Science.
Krishnarajah, Sinduya; Ingelfinger, Florian; Friebel, Ekaterina; Cansever, Dilay; Amorim, Ana; Andreadou, Myrto; Bamert, David; Litscher, Gioana; Lutz, Mirjam; Mayoux, Maud; Mundt, Sarah; Ridder, Frederike; Sparano, Colin; Stifter, Sebastian Anton; Ulutekin, Can; Unger, Susanne; Vermeer, Marijne; Zwicky, Pascale; Greter, Melanie; Tugues, Sonia; De Feo, Donatella; Becher, Burkhard (2022). Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice. Nature Aging, 2(1):74-89.
Böni, Michelle; Rieble, Lisa; Münz, Christian (2022). Co-Infection of the Epstein–Barr Virus and the Kaposi Sarcoma-Associated Herpesvirus. Viruses, 14(12):2709.
Stifter, Sebastian A; Greter, Melanie (2022). BAM! Pathogen control at the brain border. Immunity, 55(11):1969-1971.
Mundt, Sarah; Greter, Melanie; Becher, Burkhard (2022). The CNS mononuclear phagocyte system in health and disease. Neuron, 110(21):3497-3512.
Bellmann, Lydia; Strandt, Helen; Zelle-Rieser, Claudia; Ortner, Daniela; Tripp, Christoph H; Schmid, Sandra; Rühl, Julia; Cappellano, Giuseppe; Schaffenrath, Sandra; Prokopi, Anastasia; Spoeck, Sarah; Seretis, Athanasios; Del Frari, Barbara; Sigl, Stephan; Krapf, Johanna; Heufler, Christine; Keler, Tibor; Münz, Christian; Romani, Nikolaus; Stoitzner, Patrizia (2022). Targeted delivery of a vaccine protein to Langerhans cells in the human skin via the C-type lectin receptor Langerin. European Journal of Immunology, 52(11):1829-1841.
Engelmann, Christine; Schuhmachers, Patrick; Zdimerova, Hana; Virdi, Sanamjeet; Hauri-Hohl, Mathias; Pachlopnik Schmid, Jana; Grundhoff, Adam; Marsh, Rebecca A; Wong, Wendy Wei-Lynn; Münz, Christian (2022). Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1. Cell Death and Disease, 13(10):892.
Sobecki, Michal; Chen, Jing M; Krzywinska, Ewelina; Nagarajan, Shunmugam; Fan, Zheng; Nelius, Eric; Monné Rodríguez, Josep M; Seehusen, Frauke; Hussein, Amro; Moschini, Greta; Hajam, Edries Y; Kiran, Ravi; Gotthardt, Dagmar; Debbache, Julien; Badoual, Cécile; Sato, Tatsuyuki; Isagawa, Takayuki; Takeda, Norihiko; Tanchot, Corinne; Tartour, Eric; Weber, Achim; Werner, Sabine; Loffing, Johannes; Sommer, Lukas; Sexl, Veronika; Münz, Christian; Feghali-Bostwick, Carol; Pachera, Elena; Distler, Oliver; Seehusen, Frauke (2022). Vaccination-based immunotherapy to target profibrotic cells in liver and lung. Cell Stem Cell, 29(10):1459-1474.e9.
Haas, Quentin; Markov, Nikita; Muerner, Lukas; Rubino, Viviana; Benjak, Andrej; Haubitz, Monika; Baerlocher, Gabriela M; Ng, Charlotte K Y; Münz, Christian; Riether, Carsten; Ochsenbein, Adrian F; Simon, Hans-Uwe; von Gunten, Stephan (2022). Siglec-7 represents a glyco-immune checkpoint for non-exhausted effector memory CD8+ T cells with high functional and metabolic capacities. Frontiers in Immunology, 13:996746.
Ingelfinger, Florian; Sparano, Colin; Bamert, David; Reyes-Leiva, David; Sethi, Aakriti; Rindlisbacher, Lukas; Zwicky, Pascale; Kreutmair, Stefanie; Widmer, Corinne C; Mundt, Sarah; Cortés-Vicente, Elena; Tugues, Sonia; Becher, Burkhard; Schreiner, Bettina (2022). Azathioprine therapy induces selective NK cell depletion and IFN-γ deficiency predisposing to herpesvirus reactivation. Journal of Allergy and Clinical Immunology, 151(1):280-286.
Ho, Jenny N H G; Schmidt, Dominik; Lowinus, Theresa; Ryoo, Jeongmin; Dopfer, Elaine-Pashupati; Gonzalo Núñez, Nicolás; Costa-Pereira, Sara; Toffalori, Cristina; Punta, Marco; Fetsch, Viktor; Wertheimer, Tobias; Rittmann, Marie-Claire; Braun, Lukas M; Follo, Marie; Briere, Christelle; Vinnakota, Janaki Manoja; Langenbach, Marlene; Koppers, Felicitas; Shoumariyeh, Khalid; Engel, Helena; Rückert, Tamina; Märklin, Melanie; Holzmayer, Samuel; Illert, Anna L; Magon, Federica; Andrieux, Geoffroy; Duquesne, Sandra; Pfeifer, Dietmar; Staniek, Julian; Rizzi, Marta; et al (2022). Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation. Blood, 140(10):1167-1181.
Läderach, Fabienne; Münz, Christian (2022). Altered Immune Response to the Epstein-Barr Virus as a Prerequisite for Multiple Sclerosis. Cells, 11(17):2757.
Sparano, Colin; Solís-Sayago, Darío; Vijaykumar, Anjali; Rickenbach, Chiara; Vermeer, Marijne; Ingelfinger, Florian; Litscher, Gioana; Fonseca, André; Mussak, Caroline; Mayoux, Maud; Friedrich, Christin; Nombela-Arrieta, César; Gasteiger, Georg; Becher, Burkhard; Tugues, Sonia (2022). Embryonic and neonatal waves generate distinct populations of hepatic ILC1s. Science Immunology, 7(75):eabo6641.
Menges, Dominik; Zens, Kyra D; Ballouz, Tala; Caduff, Nicole; Llanas-Cornejo, Daniel; Aschmann, Hélène E; Domenghino, Anja; Pellaton, Céline; Perreau, Matthieu; Fenwick, Craig; Pantaleo, Giuseppe; Kahlert, Christian R; Münz, Christian; Puhan, Milo A; Fehr, Jan S (2022). Heterogenous humoral and cellular immune responses with distinct trajectories post-SARS-CoV-2 infection in a population-based cohort. Nature Communications, 13(1):4855.
Wang, Shanzhi; Lee, Kyeryoung; Gray, Stephen; Zhang, Yongwei; Tang, Catherine; Morrish, Rikke B; Tosti, Elena; van Oers, Johanna; Amin, Mohammad Ruhul; Cohen, Paula E; MacCarthy, Thomas; Roa, Sergio; Scharff, Matthew D; Edelmann, Winfried; Chahwan, Richard (2022). Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173A mice. Nucleic Acids Research, 50(14):8093-8106.
Sobhani, Navid; Chahwan, Richard; Roudi, Raheleh; Morris, Rachel; Volinia, Stefano; Chai, Dafei; D'Angelo, Alberto; Generali, Daniele (2022). Predictive and Prognostic Value of Non-Coding RNA in Breast Cancer. Cancers, 14(12):2952.
He, Mi; Soni, Bhavesh; Schwalie, Petra C; Hüsser, Tamara; Waltzinger, Caroline; De Silva, Duvini; Prinz, Ylva; Krümpelmann, Laura; Calabro, Samuele; Matos, Ines; Trumpfheller, Christine; Bacac, Marina; Umaña, Pablo; Levesque, Mitchell P; Dummer, Reinhard; van den Broek, Maries; Gasser, Stephan (2022). Combinations of Toll-like receptor 8 agonist TL8-506 activate human tumor-derived dendritic cells. Journal for ImmunoTherapy of Cancer, 10(6):e004268.
Pena-Francesch, Maria. The Autophagy Machinery Interacts with Epstein-Barr Virus Capsids for Viral Envelope Release. 2022, University of Zurich, Faculty of Medicine.
Al Hrout, Ala'a; Cervantes-Gracia, Karla; Chahwan, Richard; Amin, Amr (2022). Modelling liver cancer microenvironment using a novel 3D culture system. Scientific Reports, 12(1):8003.
Engelmann, Christine. Genetic and Metabolic Regulation of Epstein Barr Virus Infection. 2022, University of Zurich, Faculty of Science.
Pastor Arroyo, Eva Maria; Yassini, Nima; Sakiri, Elif; Russo, Giancarlo; Bourgeois, Soline; Mohebbi, Nilufar; Amann, Kerstin; Joller, Nicole; Wagner, Carsten A; Imenez Silva, Pedro Henrique (2022). Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease. Clinical Science, 136(8):557-577.
Hiltbrunner, Stefanie; Cords, Lena; Kasser, Sabrina; Freiberger, Sandra N; Kreutzer, Susanne; Toussaint, Nora C; Grob, Linda; Opitz, Isabelle; Messerli, Michael; Zoche, Martin; Soltermann, Alex; Rechsteiner, Markus; van den Broek, Maries; Bodenmiller, Bernd; Curioni-Fontecedro, Alessandra (2022). Acquired resistance to anti-PD1 therapy in patients with NSCLC reveals changes in T cell phenotypes and MET amplification. bioRxiv 487590v1, Cold Spring Harbor Laboratory.
Yim, Kevin Ho Wai; Borgoni, Simone; Chahwan, Richard (2022). Serum extracellular vesicles profiling is associated with COVID-19 progression and immune responses. Journal of Extracellular Biology, 1(4):e37.
Schalbetter, Sina M; von Arx, Anina S; Cruz-Ochoa, Natalia; Dawson, Kara; Ivanov, Andranik; Mueller, Flavia S; Lin, Han-Yu; Amport, René; Mildenberger, Wiebke; Mattei, Daniele; Beule, Dieter; Földy, Csaba; Greter, Melanie; Notter, Tina; Meyer, Urs (2022). Adolescence is a sensitive period for prefrontal microglia to act on cognitive development. Science Advances, 8(9):eabi6672.
Münz, Christian (2022). Canonical and Non-Canonical Functions of the Autophagy Machinery in MHC Restricted Antigen Presentation. Frontiers in Immunology, 13:868888.
Ingelfinger, Florian; Gerdes, Lisa Ann; Kavaka, Vladyslav; Krishnarajah, Sinduya; Friebel, Ekaterina; Galli, Edoardo; Zwicky, Pascale; Furrer, Reinhard; Peukert, Christian; Dutertre, Charles-Antoine; Eglseer, Klara Magdalena; Ginhoux, Florent; Flierl-Hecht, Andrea; Kümpfel, Tania; De Feo, Donatella; Schreiner, Bettina; Mundt, Sarah; Kerschensteiner, Martin; Hohlfeld, Reinhard; Beltrán, Eduardo; Becher, Burkhard (2022). Twin study reveals non-heritable immune perturbations in multiple sclerosis. Nature, 603(7899):152-158.
Münz, Christian (2022). Natural killer cell responses to human oncogenic γ-herpesvirus infections. Seminars in Immunology, 60:101652.
Fallegger, Angela; Priola, Martina; Artola-Borán, Mariela; Núñez, Nicolás Gonzalo; Wild, Sebastian; Gurtner, Alessandra; Becher, Burkhard; Yousefi, Shida; Simon, Hans-Uwe; Arnold, Isabelle C; Müller, Anne (2022). TGF-β production by eosinophils drives the expansion of peripherally induced neuropilin - RORγt + regulatory T-cells during bacterial and allergen challenge. Mucosal Immunology, 15(3):504-514.
Tallón de Lara, Paulino; Castañón, Héctor; Sterpi, Michelle; van den Broek, Maries (2022). Antimetastatic defense by CD8+ T cells. Trends in cancer, 8(2):145-157.
Panetti, Camilla; Kao, Kung‐Chi; Joller, Nicole (2022). Dampening antiviral immunity can protect the host. FEBS Journal, 289(3):634-646.
Kreutmair, Stefanie; Becher, Burkhard (2022). Response to Are NKT cells a useful predictor of COVID-19 severity? Immunity, 55(2):188-189.
Amorim, Ana; De Feo, Donatella; Friebel, Ekaterina; Ingelfinger, Florian; Anderfuhren, Cyrill Dimitri; Krishnarajah, Sinduya; Andreadou, Myrto; Welsh, Christina A; Liu, Zhaoyuan; Ginhoux, Florent; Greter, Melanie; Becher, Burkhard (2022). IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation. Nature Immunology, 23(2):217-228.
Pagliarulo, Fabio; Cheng, Phil F; Brugger, Laurin; van Dijk, Nick; van den Heijden, Michiel; Levesque, Mitchell P; Silina, Karina; van den Broek, Maries (2022). Molecular, Immunological, and Clinical Features Associated With Lymphoid Neogenesis in Muscle Invasive Bladder Cancer. Frontiers in Immunology, 12:793992.
Dick, Sarah A; Wong, Anthony; Hamidzada, Homaira; et al; Becher, Burkhard (2022). Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles. Science Immunology, 7(67):eabf7777.
Pánisová, Elena; Lünemann, Anna; Bürgler, Simone; Kotur, Monika; Lazarovici, Julien; Danu, Alina; Kaulfuss, Meike; Mietz, Juliane; Chijioke, Obinna; Münz, Christian; Busson, Pierre; Berger, Christoph; Ghez, David; Azzi, Tarik (2022). Reduced frequency of cytotoxic CD56dim CD16+ NK cells leads to impaired antibody-dependent degranulation in EBV-positive classical Hodgkin lymphoma. Cancer Immunology, Immunotherapy, 71(1):13-24.
Cervantes-Gracia, Karla; Chahwan, Richard; Husi, Holger (2022). Integrative OMICS Data-Driven Procedure Using a Derivatized Meta-Analysis Approach. Frontiers in Genetics, 13:828786.
Andreadou, Myrto; Ingelfinger, Florian; De Feo, Donatella; Friebel, Ekaterina; Tuzlak, Selma; Cramer, Teresa M L; Schreiner, Bettina; Eede, Pascale; Schneeberger, Shirin; Geesdorf, Maria; Ridder, Frederike; Welsh, Christina; Kirschenbaum, Daniel; Tyagarajan, Shiva K; Greter, Melanie; Heppner, Frank L; Mundt, Sarah; Becher, Burkhard (2022). Neuroprotective tissue adaptation induced by IL-12 attenuates CNS inflammation. bioRxiv 506749, Cold Spring Harbor Laboratory.
Münz, Christian (2021). Co-Stimulatory Molecules during Immune Control of Epstein Barr Virus Infection. Biomolecules, 12:38.
van Dijk, Nick; Gil-Jimenez, Alberto; Silina, Karina; van Montfoort, Maurits L; Einerhand, Sarah; Jonkman, Lars; Voskuilen, Charlotte S; Peters, Dennis; Sanders, Joyce; Lubeck, Yoni; Broeks, Annegien; Hooijberg, Erik; Vis, Daniel J; van den Broek, Maries; Wessels, Lodewyk F A; van Rhijn, Bas W G; van der Heijden, Michiel S (2021). The Tumor Immune Landscape and Architecture of Tertiary Lymphoid Structures in Urothelial Cancer. Frontiers in Immunology, 12:793964.
Münz, Christian (2021). Non-canonical roles of autophagy proteins in endocytosis and exocytosis. Biochemical Society Transactions, 49(6):2841-2851.
Zhang, Xiang; Schuhmachers, Patrick; Mourão, André; et al; Murer, Anita; Münz, Christian (2021). PLK1-dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV-infected mice. EMBO Reports, 22(12):e53007.
Borsa, Mariana; Barandun, Niculò; Gräbnitz, Fabienne; Barnstorf, Isabel; Baumann, Nicolas S; Pallmer, Katharina; Baumann, Samira; Stark, Dominique; Balaz, Miroslav; Oetiker, Nathalie; Wagen, Franziska; Wolfrum, Christian; Simon, Anna Katharina; Joller, Nicole; Barral, Yves; Spörri, Roman; Oxenius, Annette (2021). Asymmetric cell division shapes naive and virtual memory T-cell immunity during ageing. Nature Communications, 12:2715.
Brulefert, Adrien; Kraemer, Melanie; Cumin, Marie; Selle, Amandine; Hoste, Astrid; Gad, Hans-Henrik; Rühl, Julia; Madinier, Jean-Baptiste; Chaloin, Olivier; Münz, Christian; Desprès, Philippe; Mueller, Christopher George; Flacher, Vincent (2021). Chikungunya Virus Envelope Protein E2 Provides a Vector for Targeted Antigen Delivery to Human Dermal CD14+ Dendritic Cells. Journal of Investigative Dermatology, 141(12):2985-2989.e5.
Münz, Christian (2021). Non-canonical functions of autophagy proteins in immunity and infection. Molecular Aspects of Medicine, 82:100987.
Haftmann, Claudia; Zwicky, Pascale; Ingelfinger, Florian; Mair, Florian; et al; Becher, Burkhard (2021). Protection against autoimmunity is driven by thymic epithelial cell–mediated regulation of Treg development. Science Immunology, 6(65):eabf3111.
Ingelfinger, Florian; De Feo, Donatella; Becher, Burkhard (2021). GM-CSF: Master regulator of the T cell-phagocyte interface during inflammation. Seminars in Immunology, 54:101518.
Wyrzykowska, Paulina; Rogers, Sally; Chahwan, Richard (2021). Measuring Real-time DNA/RNA Nuclease Activity through Fluorescence. Bio-protocol, 11(21):e4206.
Srimat Kandadai, Keertana; Kotur, Monika B; Dokalis, Nikolaos; Amrein, Irmgard; Keller, Christian W; Münz, Christian; Wolfer, David; Prinz, Marco; Lünemann, Jan D (2021). ATG5 in microglia does not contribute vitally to autoimmune neuroinflammation in mice. Autophagy, 17(11):3566-3576.
Cervantes-Gracia, Karla; Gramalla-Schmitz, Anna; Weischedel, Julian; Chahwan, Richard (2021). APOBECs orchestrate genomic and epigenomic editing across health and disease. Trends in Genetics : Tig, 37(11):1028-1043.
Cevhertas, Lacin; Ma, Siyuan; Stanic, Barbara; Ochsner, Urs; Jansen, Kirstin; Ferstl, Ruth; Frei, Remo; Chijioke, Obinna; Münz, Christian; Zhang, Luo; O'Mahony, Liam; Akdis, Mübeccel; van de Veen, Willem (2021). IL-10 induces IgG4 production in NOD-scid Il2rγ null mice humanized by engraftment of peripheral blood mononuclear cells. Allergy, 76(11):3525-3529.
Forconi, Catherine S; Mulama, David H; Saikumar Lakshmi, Priya; Foley, Joslyn; Otieno, Juliana A; Kurtis, Jonathan D; Berg, Leslie J; Ong'echa, John M; Münz, Christian; Moormann, Ann M (2021). Interplay between IL-10, IFN-γ, IL-17A and PD-1 Expressing EBNA1-Specific CD4+ and CD8+ T Cell Responses in the Etiologic Pathway to Endemic Burkitt Lymphoma. Cancers, 13(21):5375.
Zwicky, Pascale; Ingelfinger, Florian; de Melo, Bruno Marcel Silva; Ruchti, Fiorella; Schärli, Stefanie; Puertas, Nicole; Lutz, Mirjam; Phan, Truong San; Kündig, Thomas M; Levesque, Mitchell P; Maul, Julia-Tatjana; Schlapbach, Christoph; LeibundGut-Landmann, Salomé; Mundt, Sarah; Becher, Burkhard (2021). IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation. Science Immunology, 6(64):eabg9012.
Läderach, Fabienne; Münz, Christian (2021). Epstein Barr Virus Exploits Genetic Susceptibility to Increase Multiple Sclerosis Risk. Microorganisms, 9(11):2191.
Gschwend, Julia; Sherman, Samantha P M; Ridder, Frederike; Feng, Xiaogang; Liang, Hong-Erh; Locksley, Richard M; Becher, Burkhard; Schneider, Christoph (2021). Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth. Journal of Experimental Medicine, 218(10)::e20210745.
Klionsky, Daniel J; Petroni, Giulia; Amaravadi, Ravi K; et al; Münz, Christian (2021). Autophagy in major human diseases. The EMBO Journal, 40(19):e108863.
Münz, Christian (2021). Kissing genetic MS risk loci to life. EBioMedicine, 72:103594.
Tuzlak, Selma; Dejean, Anne S; Iannacone, Matteo; Quintana, Francisco J; Waisman, Ari; Ginhoux, Florent; Korn, Thomas; Becher, Burkhard (2021). Repositioning T H cell polarization from single cytokines to complex help. Nature Immunology, 22(10):1210-1217.
Schneider, Marcel André; Heeb, Laura; Beffinger, Michal Mateusz; Pantelyushin, Stanislav; Linecker, Michael; Roth, Lilian; Lehmann, Kuno; Ungethüm, Udo; Kobold, Sebastian; Graf, Rolf; van den Broek, Maries; vom Berg, Johannes; Gupta, Anurag; Clavien, Pierre-Alain (2021). Attenuation of peripheral serotonin inhibits tumor growth and enhances immune checkpoint blockade therapy in murine tumor models. Science Translational Medicine, 13(611):eabc8188.
Gallerand, Alexandre; Stunault, Marion I; Merlin, Johanna; Luehmann, Hannah P; Sultan, Deborah H; Firulyova, Maria M; Magnone, Virginie; Khedher, Narges; Jalil, Antoine; Dolfi, Bastien; Castiglione, Alexia; Dumont, Adelie; Ayrault, Marion; Vaillant, Nathalie; Gilleron, Jérôme; Barbry, Pascal; Dombrowicz, David; Mack, Matthias; Masson, David; Bertero, Thomas; Becher, Burkhard; Williams, Jesse W; Zaitsev, Konstantin; Liu, Yongjian; Guinamard, Rodolphe R; Yvan-Charvet, Laurent; Ivanov, Stoyan (2021). Brown adipose tissue monocytes support tissue expansion. Nature Communications, 12:5255.
Nikiforov, Petar O; Hejja, Beata; Chahwan, Richard; Soeller, Christian; Gielen, Fabrice; Chimerel, Catalin (2021). Functional Phenotype Flow Cytometry: On Chip Sorting of Individual Cells According to Responses to Stimuli. Advanced Biology, 5(8):e2100220.
Raabe, Oksana; Birchler, Thomas; Rehrauer, Hubert; Eppler, Elisabeth (2021). CD40 Agonist Monoclonal Antibody-Mediated Hepatitis in TNF-Receptor 1 Gene Knockout Mice. Biomedicines, 9(8):863.
Kreutmair, Stefanie; Unger, Susanne; Núñez, Nicolás Gonzalo; Ingelfinger, Florian; Alberti, Chiara; De Feo, Donatella; Krishnarajah, Sinduya; Kauffmann, Manuel; Friebel, Ekaterina; Babaei, Sepideh; Gaborit, Benjamin; Lutz, Mirjam; Jurado, Nicole Puertas; Malek, Nisar P; Goepel, Siri; Rosenberger, Peter; Häberle, Helene A; Ayoub, Ikram; Al-Hajj, Sally; Nilsson, Jakob; Claassen, Manfred; Liblau, Roland; Martin-Blondel, Guillaume; Bitzer, Michael; Roquilly, Antoine; Becher, Burkhard (2021). Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia. Immunity, 54(7):1578-1593.e5.
Ducimetière, Laura; Lucchiari, Giulia; Litscher, Gioana; Nater, Marc; Heeb, Laura; Nuñez, Nicolás Gonzalo; Wyss, Laura; Burri, Dominik; Vermeer, Marijne; Gschwend, Julia; Moor, Andreas E; Becher, Burkhard; van den Broek, Maries; Tugues, Sonia (2021). Conventional NK cells and tissue-resident ILC1s join forces to control liver metastasis. Proceedings of the National Academy of Sciences of the United States of America, 118(27):e2026271118.
Lelios, Iva; Stifter, Sebastian A; Cecconi, Virginia; Petrova, Ekaterina; Lutz, Mirjam; Cansever, Dilay; Utz, Sebastian G; Becher, Burkhard; van den Broek, Maries; Greter, Melanie (2021). Monocytes promote UV‐induced epidermal carcinogenesis. European Journal of Immunology, 51(7):1799-1808.
Hering, Larissa; Katkeviciute, Egle; Schwarzfischer, Marlene; Niechcial, Anna; Riggs, Julianne B; Wawrzyniak, Marcin; Atrott, Kirstin; van de Sande, Marnix; Lang, Silvia; Becher, Burkhard; Rogler, Gerhard; Scharl, Michael; Spalinger, Marianne R (2021). Macrophages Compensate for Loss of Protein Tyrosine Phosphatase N 2 in Dendritic Cells to Protect from Elevated Colitis. International Journal of Molecular Sciences, 22(13):6820.
Münz, Christian (2021). Natural Killer Cell Responses during Human γ-Herpesvirus Infections. Vaccines, 9(6):655.
Gurtner, Alessandra; Gonzalez-Perez, Ignacio; Arnold, Isabelle C (2021). Intestinal eosinophils, homeostasis and response to bacterial intrusion. Seminars in Immunopathology, 43(3):295-306.
Nobs, Samuel Philip; Pohlmeier, Lea; Li, Fengqi; Kayhan, Merve; Becher, Burkhard; Kopf, Manfred (2021). GM-CSF instigates a dendritic cell-T-cell inflammatory circuit that drives chronic asthma development. Journal of Allergy and Clinical Immunology, 147(6):2118-2133.e3.
Stoycheva, Diana; Sandu, Ioana; Gräbnitz, Fabienne; Amorim, Ana; Borsa, Mariana; Weber, Stefan; Becher, Burkhard; Oxenius, Annette (2021). Non-neutralizing antibodies protect against chronic LCMV infection by promoting infection of inflammatory monocytes in mice. European Journal of Immunology, 51(6):1423-1435.
van Gisbergen, Klaas P J M; Zens, Kyra D; Münz, Christian (2021). T-cell memory in tissues. European Journal of Immunology, 51(6):1310-1324.
Deng, Yun; Münz, Christian (2021). Roles of Lytic Viral Replication and Co-Infections in the Oncogenesis and Immune Control of the Epstein-Barr Virus. Cancers, 13(9):2275.
Münz, Christian (2021). Regulation of the Macroautophagic Machinery, Cellular Differentiation, and Immune Responses by Human Oncogenic γ-Herpesviruses. Viruses, 13(5):859.
d'Enfert, Christophe; Kaune, Ann-Kristin; Alaban, Leovigildo-Rey; Chakraborty, Sayoni; Cole, Nathaniel; Delavy, Margot; Kosmala, Daria; Marsaux, Benoît; Fróis-Martins, Ricardo; Morelli, Moran; Rosati, Diletta; Valentine, Marisa; Xie, Zixuan; Emritloll, Yoan; Warn, Peter A; Bequet, Frédéric; Bougnoux, Marie-Elisabeth; Bornes, Stephanie; Gresnigt, Mark S; Hube, Bernhard; Jacobsen, Ilse D; Legrand, Mélanie; LeibundGut-Landmann, Salomé; Manichanh, Chaysavanh; Munro, Carol A; Netea, Mihai G; Queiroz, Karla; Roget, Karine; Thomas, Vincent; Thoral, Claudia; et al (2021). The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives. FEMS Microbiology Reviews, 45(3):fuaa060.
Keller, Christian W; Kotur, Monika B; Mundt, Sarah; Dokalis, Nikolaos; Ligeon, Laure-Anne; Shah, Ajay M; Prinz, Marco; Becher, Burkhard; Münz, Christian; Lünemann, Jan D (2021). CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation. Autophagy, 17(5):1244-1258.
Caduff, Nicole; McHugh, Donal; Rieble, Lisa; Forconi, Catherine S; Ong'echa, John M; Oluoch, Peter O; Raykova, Ana; Murer, Anita; Böni, Michelle; Zuppiger, Lara; Schulz, Thomas F; Blackbourn, David J; Chijioke, Obinna; Moormann, Ann M; Münz, Christian (2021). KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV/EBV dual infection. Cell Reports, 35(5):109056.
Sobottka-Brillout, Bettina; Lorch, Anja; Silina, Karina; van den Broek, Maries; Moch, Holger (2021). Renal cell carcinoma pathology in 2021: ‘new need for renal cancer immune profiling’. Current Opinion in Urology, 31(3):228-235.
Ho, Nataschja I; Camps, Marcel G M; Verdoes, Martijn; Münz, Christian; Ossendorp, Ferry (2021). Autophagy regulates long‐term cross‐presentation by murine dendritic cells. European Journal of Immunology, 51(4):835-847.
Ligeon, Laure-Anne; Pena-Francesch, Maria; Vanoaica, Liliana Danusia; Núñez, Nicolás Gonzalo; Talwar, Deepti; Dick, Tobias P; Münz, Christian (2021). Oxidation inhibits autophagy protein deconjugation from phagosomes to sustain MHC class II restricted antigen presentation. Nature Communications, 12:1508.
Kirchner, Florian R; LeibundGut-Landmann, Salomé (2021). Tissue-resident memory Th17 cells maintain stable fungal commensalism in the oral mucosa. Mucosal Immunology, 14(2):455-467.
Johansson, David; Rauld, Céline; Roux, Julien; Regairaz, Camille; Galli, Edoardo; Callegari, Ilaria; Raad, Layla; Waldt, Annick; Cuttat, Rachel; Roma, Guglielmo; Diebold, Martin; Becher, Burkhard; Kuhle, Jens; Derfuss, Tobias; Carballido, José M; Sanderson, Nicholas S R (2021). Mass Cytometry of CSF Identifies an MS-Associated B-cell Population. Neurology: Neuroimmunology and Neuroinflammation, 8(2):e943.
Regen, Tommy; Isaac, Sandrine; Amorim, Ana; Núñez, Nicolás Gonzalo; Hauptmann, Judith; Shanmugavadivu, Arthi; Klein, Matthias; Sankowski, Roman; Mufazalov, Ilgiz A; Yogev, Nir; Huppert, Jula; Wanke, Florian; Witting, Michael; Grill, Alexandra; Gálvez, Eric J C; Nikolaev, Alexei; Blanfeld, Michaela; Prinz, Immo; Schmitt-Kopplin, Philippe; Strowig, Till; Reinhardt, Christoph; Prinz, Marco; Bopp, Tobias; Becher, Burkhard; Ubeda, Carles; Waisman, Ari (2021). IL-17 controls central nervous system autoimmunity through the intestinal microbiome. Science Immunology, 6(56):eaaz6563.
Münz, Christian (2021). Cytotoxicity in Epstein Barr virus specific immune control. Current Opinion in Virology, 46:1-8.
Sanmarco, Liliana M; Wheeler, Michael A; Gutiérrez-Vázquez, Cristina; Polonio, Carolina Manganeli; Linnerbauer, Mathias; Pinho-Ribeiro, Felipe A; Li, Zhaorong; Giovannoni, Federico; Batterman, Katelyn V; Scalisi, Giulia; Zandee, Stephanie E J; Heck, Evelyn S; Alsuwailm, Moneera; Rosene, Douglas L; Becher, Burkhard; Chiu, Isaac M; Prat, Alexandre; Quintana, Francisco J (2021). Gut-licensed IFNγ + NK cells drive LAMP1 + TRAIL + anti-inflammatory astrocytes. Nature, 590(7846):473-479.
Agliardi, Giulia; Liuzzi, Anna Rita; Hotblack, Alastair; De Feo, Donatella; Núñez, Nicolás Gonzalo; Stowe, Cassandra L; Friebel, Ekaterina; Nannini, Francesco; Rindlisbacher, Lukas; Roberts, Thomas A; Ramasawmy, Rajiv; Williams, Iwan P; Siow, Bernard M; Lythgoe, Mark F; Kalber, Tammy L; Quezada, Sergio A; Pule, Martin A; Tugues, Sonia; Straathof, Karin; Becher, Burkhard (2021). Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma. Nature Communications, 12:444.
Volk, Valery; Theobald, Sebastian J; Danisch, Simon; Khailaie, Sahamoddin; Kalbarczyk, Maja; Schneider, Andreas; Bialek-Waldmann, Julia; Krönke, Nicole; Deng, Yun; Eiz-Vesper, Britta; Dragon, Anna Christina; von Kaisenberg, Constantin; Lienenklaus, Stefan; Bleich, Andre; Keck, James; Meyer-Hermann, Michael; Klawonn, Frank; Hammerschmidt, Wolfgang; Delecluse, Henri-Jacques; Münz, Christian; Feuerhake, Friedrich; Stripecke, Renata (2021). PD-1 Blockade Aggravates Epstein–Barr Virus+ Post-Transplant Lymphoproliferative Disorder in Humanized Mice Resulting in Central Nervous System Involvement and CD4+ T Cell Dysregulations. Frontiers in Oncology, 10:614876.
Wang, Ming; Yang, Yalong; Cansever, Dilay; et al; Becher, Burkhard; Greter, Melanie (2021). Two populations of self-maintaining monocyte-independent macrophages exist in adult epididymis and testis. Proceedings of the National Academy of Sciences of the United States of America, 118(1):e2013686117.
Zdimerova, Hana; Murer, Anita; Engelmann, Christine; Raykova, Ana; Deng, Yun; Gujer, Cornelia; Rühl, Julia; McHugh, Donal; Caduff, Nicole; Naghavian, Reza; Pezzino, Gaetana; Capaul, Riccarda; Zbinden, Andrea; Ferlazzo, Guido; Lünemann, Jan D; Martin, Roland; Chatterjee, Bithi; Münz, Christian (2021). Attenuated immune control of Epstein-Barr virus in humanized mice is associated with the multiple sclerosis risk factor HLA-DR15. European Journal of Immunology, 51(1):64-75.
Blümich, Sandra; Zdimerova, Hana; Münz, Christian; Kipar, Anja; Pellegrini, Giovanni (2021). Human CD34+ Hematopoietic Stem Cell–Engrafted NSG Mice: Morphological and Immunophenotypic Features. Veterinary Pathology, 58(1):161-180.
Hiltbrunner, S; Britschgi, C; Schuberth, P; Bankel, L; Nguyen-Kim, T D L; Gulati, P; Weder, W; Opitz, I; Lauk, O; Caviezel, C; Bachmann, H; Tabor, A; Schröder, P; Knuth, A; Münz, C; Stahel, R; Boyman, O; Renner, C; Petrausch, U; Curioni-Fontecedro, A (2021). Local delivery of CAR T cells targeting fibroblast activation protein is safe in patients with pleural mesothelioma: first report of FAPME, a phase I clinical trial. Annals of Oncology, 32(1):120-121.
Klionsky, Daniel J; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; et al; Bornhauser, Beat C (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1):1-382.
Zens, Kyra D; Baroutsou, Vasiliki; Sinniger, Philipp; Lang, Phung (2021). A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland. PLoS ONE, 16(12):e0247216.
Münz, Christian (2021). Antiviral Targeting of the Complex Epstein Barr Virus Life Cycle. In: Rübsamen-Schaeff, Helga; Buschmann, Helmut. New Drug Development for Known and Emerging Viruses. Weinheim: Wiley-VCH, 175-190.
Palombo, Francesca; Pagliara, Stefano; Singh, Ankur; Chahwan, Richard (2021). Editorial: Probing the Chromatin Architecture. Frontiers in Cell and Developmental Biology, 9:727803.
Münz, Christian (2021). Immune Escape by Non-coding RNAs of the Epstein Barr Virus. Frontiers in Microbiology, 12:657387.
Cervantes-Gracia, Karla; Chahwan, Richard; Husi, Holger (2021). Integrative Analysis of Incongruous Cancer Genomics and Proteomics Datasets. Methods in Molecular Biology, 2361:291-305.
Ligeon, Laure-Anne; Pena-Francesch, Maria; Münz, Christian (2021). Measuring oxidation within LC3-associated phagosomes that optimizes MHC class II restricted antigen presentation. Methods in Cell Biology, 164:187-200.
Hrout, Ala’a Al; Cervantes-Gracia, Karla; Chahwan, Richard; Amin, Amr (2021). Modelling liver cancer microenvironment: novel 3D culture system as a potential anti-cancer drug screening tool. bioRxiv 467266, Cold Spring Harbor Laboratory.
Schuhmachers, Patrick; Münz, Christian (2021). Modification of EBV Associated Lymphomagenesis and Its Immune Control by Co-Infections and Genetics in Humanized Mice. Frontiers in Immunology, 12:640918.
Münz, Christian (2021). Modification of EBV-Associated Pathologies and Immune Control by Coinfections. Frontiers in Oncology, 11:756480.
Morrish, Rikke; Yim, Kevin Ho Wai; Pagliara, Stefano; Palombo, Francesca; Chahwan, Richard; Stone, Nicholas (2021). Single Cell Label-Free Probing of Chromatin Dynamics During B Lymphocyte Maturation. Frontiers in Cell and Developmental Biology, 9:646616.
Morrish, Rikke; Yim, Kevin Ho Wai; Pagliara, Stefano; Palombo, Francesca; Chahwan, Richard; Stone, Nicholas (2021). Single cell label-free probing of chromatin dynamics during B lymphocyte maturation. bioRxiv 426344, Cold Spring Harbor Laboratory.
Münz, Christian (2021). The Macroautophagy Machinery in MHC Restricted Antigen Presentation. Frontiers in Immunology, 12:628429.
Münz, Christian (2021). The Role of Lytic Infection for Lymphomagenesis of Human γ-Herpesviruses. Frontiers in Cellular and Infection Microbiology, 11:605258.
Stirm, Kristin; Leary, Peter; Bertram, Katrin; Núñez, Nicolás Gonzalo; Wüst, Daria; Boudesco, Christophe; Verhoeyen, Els; Zenz, Thorsten; Becher, Burkhard; Menter, Thomas; Tzankov, Alexandar; Müller, Anne (2021). Tumor cell-derived IL-10 promotes cell-autonomous growth and immune escape in diffuse large B-cell lymphoma. OncoImmunology, 10(1):2003533.
Estrada Brull, Anna; Rost, Felix; Oderbolz, Josua; Kirchner, Florian R; Leibundgut-Landmann, Salomé; Oxenius, Annette; Joller, Nicole (2020). CD85k Contributes to Regulatory T Cell Function in Chronic Viral Infections. International Journal of Molecular Sciences, 22(1):31.
Yim, Kevin Ho Wai; Al Hrout, Ala'a; Borgoni, Simone; Chahwan, Richard (2020). Extracellular Vesicles Orchestrate Immune and Tumor Interaction Networks. Cancers, 12(12):3696.
Keller, Christian W; Münz, Christian; Lünemann, Jan D (2020). Autophagy Pathways in CNS Myeloid Cell Immune Functions. Trends in Neurosciences, 43(12):1024-1033.
Rost, Felix; Lambert, Katharina; Rakebrandt, Nikolas; Joller, Nicole (2020). Preceding Viral Infections Do Not Imprint Long-Term Changes in Regulatory T Cell Function. Scientific Reports, 10:8350.
van Dijk, Nick; Gil-Jimenez, Alberto; Silina, Karina; Hendricksen, Kees; Smit, Laura A; de Feijter, Jeantine M; van Montfoort, Maurits L; van Rooijen, Charlotte; Peters, Dennis; Broeks, Annegien; van der Poel, Henk G; Bruining, Annemarie; Lubeck, Yoni; Sikorska, Karolina; Boellaard, Thierry N; Kvistborg, Pia; Vis, Daniel J; Hooijberg, Erik; Schumacher, Ton N; van den Broek, Maries; Wessels, Lodewyk F A; Blank, Christian U; van Rhijn, Bas W; van der Heijden, Michiel S (2020). Preoperative ipilimumab plus nivolumab in locoregionally advanced urothelial cancer: the NABUCCO trial. Nature Medicine, 26(12):1839-1844.
Schorer, Michelle; Rakebrandt, Nikolas; Lambert, Katharina; Hunziker, Annika; Pallmer, Katharina; Oxenius, Annette; Kipar, Anja; Stertz, Silke; Joller, Nicole (2020). TIGIT limits immune pathology during viral infections. Nature Communications, 11(1):1288.
Guendel, Fabian; Kofoed-Branzk, Michael; Gronke, Konrad; et al; Cheng, Hung-Wei; Becher, Burkhard (2020). Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues. Immunity, 53(5):1015-1032.e8.
Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of Immunology, 205(10):2640-2648.
Münz, Christian (2020). Autophagy proteins influence endocytosis for MHC restricted antigen presentation. Seminars in Cancer Biology, 66:110-115.
Wang, Jian; Jelcic, Ivan; Mühlenbruch, Lena; Haunerdinger, Veronika; Toussaint, Nora C; Zhao, Yingdong; Cruciani, Carolina; Faigle, Wolfgang; Naghavian, Reza; Foege, Magdalena; Binder, Thomas M C; Eiermann, Thomas; Opitz, Lennart; Fuentes-Font, Laura; Reynolds, Richard; Kwok, William W; Nguyen, Julie T; Lee, Jar-How; Lutterotti, Andreas; Münz, Christian; Rammensee, Hans-Georg; Hauri-Hohl, Mathias; Sospedra, Mireia; Stevanovic, Stefan; Martin, Roland (2020). HLA-DR15 molecules jointly shape an autoreactive T cell repertoire in multiple sclerosis. Cell, 183(5):1264-1281.e20.
Rühl, Julia; Leung, Carol S; Münz, Christian (2020). Vaccination against the Epstein–Barr virus. Cellular and Molecular Life Sciences, 77(21):4315-4324.
Rajewsky, Nikolaus; Almouzni, Geneviève; Gorski, Stanislaw A; et al; Becher, Burkhard (2020). LifeTime and improving European healthcare through cell-based interceptive medicine. Nature, 587(7834):377-386.
Deng, Yun. The Role of the Co-Stimulatory Molecule CD27 in EBV Specific Immune Control. 2020, University of Zurich, Faculty of Science.
Boscardin, Silvia Beatriz; Dudziak, Diana; Münz, Christian; Rosa, Daniela Santoro (2020). Editorial: Harnessing the Participation of Dendritic Cells in Immunity and Tolerance. Frontiers in Immunology, 11:595841.
Myburgh, Renier; Kiefer, Jonathan D; Russkamp, Norman F; Magnani, Chiara F; Núñez, Nicolás Gonzalo; Simonis, Alexander; Pfister, Surema; Wilk, C Matthias; McHugh, Donal; Friemel, Juliane; Müller, Antonia M; Becher, Burkhard; Münz, Christian; van den Broek, Maries; Neri, Dario; Manz, Markus G (2020). Anti-human CD117 CAR T-cells efficiently eliminate healthy and malignant CD117-expressing hematopoietic cells. Leukemia, 34(10):2688-2703.
Caduff, Nicole. Regulation of Gammaherpesvirus Immune Control by Co-Infection or Immune Suppression. 2020, University of Zurich, Faculty of Science.
Münz, Christian (2020). Probing Reconstituted Human Immune Systems in Mice With Oncogenic γ-Herpesvirus Infections. Frontiers in Immunology, 11:581419.
Giger, Sonja; Kovtonyuk, Larisa V; Utz, Sebastian G; Ramosaj, Mergim; Kovacs, Werner J; Schmid, Emanuel; Ioannidis, Vassilios; Greter, Melanie; Manz, Markus G; Lutolf, Matthias P; Jessberger, Sebastian; Knobloch, Marlen (2020). A single metabolite which modulates lipid metabolism alters hematopoietic stem/progenitor cell behavior and promotes lymphoid reconstitution. Stem Cell Reports, 15(3):566-576.
Barnstorf, Isabel; Welten, Suzanne P M; Borsa, Mariana; Baumann, Nicolas S; Pallmer, Katharina; Joller, Nicole; Spörri, Roman; Oxenius, Annette (2020). Chronic viral infections impinge on naive bystander CD8 T cells. Immunity, Inflammation and Disease, 8(3):249-257.
McHugh, Donal; Myburgh, Renier; Caduff, Nicole; Spohn, Michael; Kok, Yik Lim; Keller, Christian W; Murer, Anita; Chatterjee, Bithi; Rühl, Julia; Engelmann, Christine; Chijioke, Obinna; Quast, Isaak; Shilaih, Mohaned; Strouvelle, Victoria P; Neumann, Kathrin; Menter, Thomas; Dirnhofer, Stephan; Lam, Janice K P; Hui, Kwai F; Bredl, Simon; Schlaepfer, Erika; Sorce, Silvia; Zbinden, Andrea; Capaul, Riccarda; Lünemann, Jan D; Aguzzi, Adriano; Chiang, Alan K S; Kempf, Werner; Trkola, Alexandra; Metzner, Karin J; et al (2020). EBV renders B cells susceptible to HIV-1 in humanized mice. Life Science Alliance, 3(8):e202000640.
Lang, Frederick M; Lee, Kevin M-C; Teijaro, John R; Becher, Burkhard; Hamilton, John A (2020). GM-CSF-based treatments in COVID-19: reconciling opposing therapeutic approaches. Nature Reviews. Immunology, 20(8):507-514.
Stripecke, Renata; Münz, Christian; Schuringa, Jan Jacob; Bissig, Karl‐Dimiter; Soper, Brian; Meeham, Terrence; Yao, Li‐Chin; Di Santo, James P; Brehm, Michael; Rodriguez, Estefania; Wege, Anja Kathrin; Bonnet, Dominique; Guionaud, Silvia; Howard, Kristina E; Kitchen, Scott; Klein, Florian; Saeb‐Parsy, Kourosh; Sam, Johannes; Sharma, Amar Deep; Trumpp, Andreas; Trusolino, Livio; Bult, Carol; Shultz, Leonard (2020). Innovations, challenges, and minimal information for standardization of humanized mice. EMBO Molecular Medicine, 12(7):e8662.
Xiao, Sheng; Bod, Lloyd; Pochet, Nathalie; Kota, Savithri Balasubramanian; Hu, Dan; Madi, Asaf; Kilpatrick, Jessica; Shi, Jingwen; Ho, Allen; Zhang, Huiyuan; Sobel, Raymond; Weiner, Howard L; Strom, Terry B; Quintana, Francisco J; Joller, Nicole; Kuchroo, Vijay K (2020). Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation. Cell Reports, 32(2):107892.
Joller, Nicole (2020). Type 1 Treg cells act as unexpected helpers. Nature Immunology, 21(7):720-721.
Lam, Janice K P; Azzi, Tarik; Hui, K F; Wong, Aikha M G; McHugh, Donal; Caduff, Nicole; Chan, K H; Münz, Christian; Chiang, Alan K S (2020). Co-infection of Cytomegalovirus and Epstein-Barr Virus Diminishes the Frequency of CD56dimNKG2A+KIR− NK Cells and Contributes to Suboptimal Control of EBV in Immunosuppressed Children With Post-transplant Lymphoproliferative Disorder. Frontiers in Immunology, 11:1231.
Oluoch, Peter O; Oduor, Cliff I; Forconi, Catherine S; Ong’echa, John M; Münz, Christian; Dittmer, Dirk P; Bailey, Jeffrey A; Moormann, Ann M (2020). Kaposi Sarcoma-Associated Herpesvirus Infection and Endemic Burkitt Lymphoma. Journal of Infectious Diseases, 222(1):111-120.
Münz, Christian (2020). Redirecting T Cells against Epstein–Barr Virus Infection and Associated Oncogenesis. Cells, 9(6):1400.
Becher, Burkhard; De Feo, Donatella; Amorim, Ana; Greter, Melanie (2020). Skipping adolescence to become super-inflammatory monocytes. Nature Immunology, 21(5):491-492.
Utz, Sebastian G; See, Peter; Mildenberger, Wiebke; Thion, Morgane Sonia; Silvin, Aymeric; Lutz, Mirjam; Ingelfinger, Florian; Rayan, Nirmala Arul; Lelios, Iva; Buttgereit, Anne; Asano, Kenichi; Prabhakar, Shyam; Garel, Sonia; Becher, Burkhard; Ginhoux, Florent; Greter, Melanie (2020). Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development. Cell, 181(3):557-573.e18.
Forconi, Catherine S; Oduor, Cliff I; Oluoch, Peter O; Ong'echa, John M; Münz, Christian; Bailey, Jeffrey A; Moormann, Ann M (2020). A New Hope for CD56negCD16pos NK Cells as Unconventional Cytotoxic Mediators: An Adaptation to Chronic Diseases. Frontiers in Cellular and Infection Microbiology, 10:162.
Reed-Geaghan, Erin G; Croxford, Andrew L; Becher, Burkhard; Landreth, Gary E (2020). Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model. Journal of Experimental Medicine, 217(4):e20191374.
Hamarsheh, Shaima'a; Osswald, Lena; Saller, Benedikt S; Unger, Susanne; De Feo, Donatella; et al; Becher, Burkhard (2020). Oncogenic Kras G12D causes myeloproliferation via NLRP3 inflammasome activation. Nature Communications, 11:1659.
Caduff, Nicole; McHugh, Donal; Murer, Anita; Rämer, Patrick; Raykova, Ana; Landtwing, Vanessa; Rieble, Lisa; Keller, Christian W; Prummer, Michael; Hoffmann, Laurent; Lam, Janice K P; Chiang, Alan K S; Raulf, Friedrich; Azzi, Tarik; Berger, Christoph; Rubic-Schneider, Tina; Traggiai, Elisabetta; Lünemann, Jan D; Kammüller, Michael; Münz, Christian (2020). Immunosuppressive FK506 treatment leads to more frequent EBV-associated lymphoproliferative disease in humanized mice. PLoS Pathogens, 16(4):e1008477.
Rost, Felix. Memory Formation and Functional Specialization of Regulatory T Cells in TH1-polarized Immune Responses. 2020, University of Zurich, Faculty of Science.
Tewari, Damini; Cook, Andrew D; Lee, Ming-Chin; Christensen, Anne D; Croxford, Andrew; Becher, Burkhard; Poole, Daniel; Rajasekhar, Pradeep; Bunnett, Nigel; Smith, Julia E; Hamilton, John A; McMahon, Stephen B (2020). Granulocyte-macrophage colony stimulating factor as an indirect mediator of nociceptor activation and pain. Journal of Neuroscience, 40(11):2189-2199.
Chitu, Violeta; Biundo, Fabrizio; Shlager, Gabriel G L; Park, Eun S; Wang, Ping; Gulinello, Maria E; Gokhan, Şölen; Ketchum, Harmony C; Saha, Kusumika; DeTure, Michael A; Dickson, Dennis W; Wszolek, Zbignew K; Zheng, Deyou; Croxford, Andrew L; Becher, Burkhard; Sun, Daqian; Mehler, Mark F; Stanley, E Richard (2020). Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling. Cell Reports, 30(9):3004-3019.e5.
Aslan, Katrin; Turco, Verena; Blobner, Jens; et al; Liuzzi, Anna Rita; Núñez, Nicolás Gonzalo; De Feo, Donatella; Becher, Burkhard (2020). Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas. Nature Communications, 11(1):931.
Wheeler, Michael A; Clark, Iain C; Tjon, Emily C; Li, Zhaorong; Zandee, Stephanie E J; Couturier, Charles P; Watson, Brianna R; Scalisi, Giulia; Alkwai, Sarah; Rothhammer, Veit; Rotem, Assaf; Heyman, John A; Thaploo, Shravan; Sanmarco, Liliana M; Ragoussis, Jiannis; Weitz, David A; Petrecca, Kevin; Moffitt, Jeffrey R; Becher, Burkhard; Antel, Jack P; Prat, Alexandre; Quintana, Francisco J (2020). MAFG-driven astrocytes promote CNS inflammation. Nature, 578(7796):593-599.
Arsiwala, Tasneem; Pahla, Jürgen; van Tits, Lambertus J; Bisceglie, Lavinia; Gaul, Daniel S; Costantino, Sarah; Miranda, Melroy X; Nussbaum, Kathrin; Stivala, Simona; Blyszczuk, Przemyslaw; Weber, Julien; Tailleux, Anne; Stein, Sokrates; Paneni, Francesco; Beer, Jürg H; Greter, Melanie; Becher, Burkhard; Mostoslavsky, Raul; Eriksson, Urs; Staels, Bart; Auwerx, Johan; Hottiger, Michael O; Lüscher, Thomas F; Matter, Christian M (2020). Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1. Journal of Molecular and Cellular Cardiology, 139:24-32.
Apostolova, Petya; Unger, Susanne; von Bubnoff, Dagmar; Meiss, Frank; Becher, Burkhard; Zeiser, Robert (2020). Extracorporeal photopheresis for colitis induced by checkpoint-inhibitor therapy. New England Journal of Medicine, 382(3):294-296.
Antel, Jack P; Becher, Burkhard; Ludwin, Samuel K; Prat, Alexandre; Quintana, Francisco J (2020). Glial cells as regulators of neuroimmune interactions in the central nervous system. Journal of Immunology, 204(2):251-255.
Zwicky, Pascale; Unger, Susanne; Becher, Burkhard (2020). Targeting interleukin-17 in chronic inflammatory disease: a clinical perspective. Journal of Experimental Medicine, 217(1):e20191123.
Münz, Christian (2020). Autophagy in immunity. In: Kasselman, Lora. Progress in Molecular Biology and Translational Science. United States: Elsevier, 67-85.
Münz, Christian (2020). Tumor Microenvironment Conditioning by Abortive Lytic Replication of Oncogenic γ-Herpesviruses. In: Birbrair, Alexander. Tumor Microenvironment. Cham: Springer, 127-135.
Schorer, Michelle; Lambert, Katharina; Rakebrandt, Nikolas; Rost, Felix; Kao, Kung-Chi; Yermanos, Alexander; Spörri, Roman; Oderbolz, Josua; Raeber, Miro E; Keller, Christian W; Lünemann, Jan D; Rogler, Gerhard; Boyman, Onur; Oxenius, Annette; Joller, Nicole (2020). Rapid expansion of Treg cells protects from collateral colitis following a viral trigger. Nature Communications, 11:1522.
Münz, Christian (2019). Immune Control and Vaccination against the Epstein-Barr Virus in Humanized Mice. Vaccines, 7(4):E217.
Münz, Christian (2019). The Role of Dendritic Cells in Immune Control and Vaccination against $y$-Herpesviruses. Viruses, 11(12):E1125.
Keller, Christian W; Ruck, Tobias; McHugh, Donal; Pfeuffer, Steffen; Gross, Catharina C; Korsukewitz, Catharina; Melzer, Nico; Klotz, Luisa; Meuth, Sven G; Münz, Christian; Nimmerjahn, Falk; Wiendl, Heinz; Lünemann, Jan D (2019). Impact of FcγR variants on the response to alemtuzumab in multiple sclerosis. Annals of Clinical and Translational Neurology, 6(12):2586-2594.
Yiu, Stephanie Pei Tung; Hui, Kwai Fung; Münz, Christian; Lo, Kwok-Wai; Tsao, Sai Wah; Kao, Richard Yi Tsun; Yang, Dan; Chiang, Alan Kwok Shing (2019). Autophagy-Dependent Reactivation of Epstein-Barr Virus Lytic Cycle and Combinatorial Effects of Autophagy-Dependent and Independent Lytic Inducers in Nasopharyngeal Carcinoma. Cancers, 11(12):E1871.
Martí i Líndez, Adrià-Arnau; Dunand-Sauthier, Isabelle; Conti, Mark; Gobet, Florian; Núñez, Nicolás; Hannich, J Thomas; Riezman, Howard; Geiger, Roger; Piersigilli, Alessandra; Hahn, Kerstin; Lemeille, Sylvain; Becher, Burkhard; De Smedt, Thibaut; Hugues, Stéphanie; Reith, Walter (2019). Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacy. Journal of Clinical Investigation Insight, 4(24):132975.
Münz, Christian (2019). Latency and lytic replication in Epstein-Barr virus-associated oncogenesis. Nature Reviews. Microbiology, 17(11):691-700.
Tisch, Nathalie; Freire-Valls, Aida; Yerbes, Rosario; Paredes, Isidora; La Porta, Silvia; Wang, Xiaohong; Martín-Pérez, Rosa; Castro, Laura; Wong, Wendy Wei-Lynn; Coultas, Leigh; Strilic, Boris; Gröne, Hermann-Josef; Hielscher, Thomas; Mogler, Carolin; Adams, Ralf H; Heiduschka, Peter; Claesson-Welsh, Lena; Mazzone, Massimiliano; López-Rivas, Abelardo; Schmidt, Thomas; Augustin, Hellmut G; de Almodovar, Carmen Ruiz (2019). Caspase-8 modulates physiological and pathological angiogenesis during retina development. Journal of Clinical Investigation, 129(12):5092-5107.
Becher, B; Waisman, A; Lu, L F (2019). Cre-lox: Target Sensitivity Matters. Immunity, 51(4):595.
Hülsdünker, Jan; Thomas, Oliver S; Haring, Eileen; Unger, Susanne; Gonzalo Núñez, Nicolás; Tugues, Sonia; Gao, Zhan; Duquesne, Sandra; Cywes-Bentley, Colette; Oyardi, Ozlem; Kirschnek, Susanne; Schmitt-Graeff, Annette; Pabst, Oliver; Koenecke, Christian; Duyster, Justus; Apostolova, Petya; Blaser, Martin J; Becher, Burkhard; Pier, Gerald B; Häcker, Georg; Zeiser, Robert (2019). Immunization against poly--acetylglucosamine reduces neutrophil activation and GVHD while sparing microbial diversity. Proceedings of the National Academy of Sciences of the United States of America, 116(41):20700-20706.
Hou, Lifei; Rao, Deepak A; Yuki, Koichi; Cooley, Jessica; Henderson, Lauren A; Jonsson, A Helena; Kaiserman, Dion; Gorman, Mark P; Nigrovic, Peter A; Bird, Phillip I; Becher, Burkhard; Remold-O'Donnell, Eileen (2019). SerpinB1 controls encephalitogenic T helper cells in neuroinflammation. Proceedings of the National Academy of Sciences of the United States of America, 116(41):20635-20643.
Rauschmeier, René; Gustafsson, Charlotte; Reinhardt, Annika; A‐Gonzalez, Noelia; Tortola, Luigi; Cansever, Dilay; Subramanian, Sethuraman; Taneja, Reshma; Rossner, Moritz J; Sieweke, Michael H; Greter, Melanie; Månsson, Robert; Busslinger, Meinrad; Kreslavsky, Taras (2019). Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self‐renewal and identity. The EMBO Journal, 38(19):e101233.
Schadt, Linda; Sparano, Colin; Schweiger, Nicole Angelika; Silina, Karina; Cecconi, Virginia; Lucchiari, Giulia; Yagita, Hideo; Guggisberg, Emilien; Saba, Sascha; Nascakova, Zuzana; Barchet, Winfried; van den Broek, Maries (2019). Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity. Cell Reports, 29(5):1236-1248.e7.
Cossarizza, Andrea; Chang, Hyun‐Dong; Radbruch, Andreas; et al; Akdis, Mübeccel; Becher, Burkhard; Kopf, M; LeibundGut-Landmann, Salomé (2019). Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European Journal of Immunology, 49(10):1457-1973.
Deretic, Vojo; Prossnitz, Eric; Burge, Mark; Campen, Matthew J; Cannon, Judy; Liu, Ke Jian; Liu, Meilian; Hall, Pamela; Sklar, Larry A; Allers, Lee; Mariscal, Luisa; Garcia, Sally Ann; Weaver, John; Baehrecke, Eric H; Behrends, Christian; Cecconi, Francesco; Codogno, Patrice; Chen, Guang-Chao; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fourie, Bernard; Gozuacik, Devrim; Hong, Wanjin; Jo, Eun-Kyeong; Johansen, Terje; Juhász, Gábor; Kimchi, Adi; Ktistakis, Nicholas; Kroemer, Guido; Mizushima, Noboru; et al (2019). Autophagy, Inflammation, and Metabolism (AIM) Center in its second year. Autophagy, 15(10):1829-1833.
Mundt, Sarah; Greter, Melanie; Flügel, Alexander; Becher, Burkhard (2019). The CNS Immune Landscape from the Viewpoint of a T Cell. Trends in Neurosciences, 42(10):667-679.
Knop, Janin; Spilgies, Lisanne M; Rufli, Stefanie; Reinhart, Ramona; Vasilikos, Lazaros; Yabal, Monica; Owsley, Erika; Jost, Philipp J; Marsh, Rebecca A; Wajant, Harald; Robinson, Mark D; Kaufmann, Thomas; Wong, W Wei-Lynn (2019). TNFR2 induced priming of the inflammasome leads to a RIPK1-dependent cell death in the absence of XIAP. Cell Death and Disease, 10(10):700.
Rizk, John; Kaplinsky, Joseph; Agerholm, Rasmus; Kadekar, Darshana; Ivars, Fredrik; Agace, William W; Wong, W Wei-Lynn; Szucs, Matthew J; Myers, Samuel A; Carr, Steven A; Waisman, Ari; Bekiaris, Vasileios (2019). SMAC mimetics promote NIK-dependent inhibition of CD4+ TH17 cell differentiation. Science Signaling, 12(596):eaaw3469.
Galli, Edoardo; Hartmann, Felix J; Schreiner, Bettina; Ingelfinger, Florian; Arvaniti, Eirini; Diebold, Martin; Mrdjen, Dunja; van der Meer, Franziska; Krieg, Carsten; Nimer, Faiez Al; Sanderson, Nicholas; Stadelmann, Christine; Khademi, Mohsen; Piehl, Fredrik; Claassen, Manfred; Derfuss, Tobias; Olsson, Tomas; Becher, Burkhard (2019). GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis. Nature Medicine, 25(8):1290-1300.
Roquilly, A; Torres, A; Villadangos, J A; Netea, M G; Dickson, R; Becher, B; Asehnoune, K (2019). Pathophysiological role of respiratory dysbiosis in hospital-acquired pneumonia. Lancet Respiratory Medicine, 7(8):710-720.
Brummelman, Jolanda; Haftmann, Claudia; Núñez, Nicolás Gonzalo; Alvisi, Giorgia; Mazza, Emilia M C; Becher, Burkhard; Lugli, Enrico (2019). Development, application and computational analysis of high-dimensional fluorescent antibody panels for single-cell flow cytometry. Nature Protocols, 14(7):1946-1969.
Schorer, Michelle. The Role of The Co-inhibitory Receptor TIGIT During Viral Infections. 2019, University of Zurich, Faculty of Science.
Sheppard, Emily C; Rogers, Sally; Harmer, Nicholas J; Chahwan, Richard (2019). A universal fluorescence-based toolkit for real-time quantification of DNA and RNA nuclease activity. Scientific Reports, 9(1):8853.
Utz, Sebastian G; Greter, Melanie (2019). Checking macrophages at the border. Nature Neuroscience, 22(6):848-850.
Rakebrandt, Nikolas; Joller, Nicole (2019). Infection History Determines Susceptibility to Unrelated Diseases. BioEssays, 41(6):e1800191.
Zens, Kyra; Münz, Christian (2019). Tissue resident T cell memory or how the magnificent seven are chilling in the bone. European Journal of Immunology, 49(6):849-852.
McHugh, Donal; Caduff, Nicole; Murer, Anita; Engelmann, Christine; Deng, Yun; Zdimerova, Hana; Zens, Kyra; Chijioke, Obinna; Münz, Christian (2019). Infection and immune control of human oncogenic γ-herpesviruses in humanized mice. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 374(1773):20180296.
Komuczki, Juliana; Tuzlak, Selma; Friebel, Ekaterina; Hartwig, Tom; Spath, Sabine; Rosenstiel, Philip; Waisman, Ari; Opitz, Lennart; Oukka, Mohammed; Schreiner, Bettina; Pelczar, Pawel; Becher, Burkhard (2019). Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β. Immunity, 50(5):1289-1304.e6.
Rühl, Julia; Citterio, Carmen; Engelmann, Christine; Haigh, Tracey; Dzionek, Andrzej; Dreyer, Johannes; Khanna, Rajiv; Taylor, Graham S; Wilson, Joanna B; Leung, Carol S; Münz, Christian (2019). Heterologous prime-boost vaccination protects against EBV antigen-expressing lymphomas. Journal of Clinical Investigation, 129(5):2071-2087.
Chatterjee, Bithi; Deng, Yun; Holler, Angelika; Núñez, Nicolás Gonzalo; Azzi, Tarik; Vanoaica, Liliana Danusia; Müller, Anne; Zdimerova, Hana; Antsiferova, Olga; Zbinden, Andrea; Capaul, Riccarda; Dreyer, Johannes H; Nadal, David; Becher, Burkhard; Robinson, Mark D; Stauss, Hans; Münz, Christian (2019). CD8+ T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo. PLoS Pathogens, 15(5):e1007748.
Gujer, Cornelia; Murer, Anita; Müller, Anne; Vanoaica, Danusia; Sutter, Kathrin; Jacque, Emilie; Fournier, Nathalie; Kalchschmidt, Jens; Zbinden, Andrea; Capaul, Riccarda; Dzionek, Andrzej; Mondon, Philippe; Dittmer, Ulf; Münz, Christian (2019). Plasmacytoid dendritic cells respond to Epstein-Barr virus infection with a distinct type I interferon subtype profile. Blood Advances, 3(7):1129-1144.
Dorhoi, Anca; Glaría, Estibaliz; Garcia-Tellez, Thalia; Nieuwenhuizen, Natalie E; Zelinskyy, Gennadiy; Favier, Benoit; Singh, Anurag; Ehrchen, Jan; Gujer, Cornelia; Münz, Christian; Saraiva, Margarida; Sohrabi, Yahya; Sousa, Ana E; Delputte, Peter; Müller-Trutwin, Michaela; Valledor, Annabel F (2019). MDSCs in infectious diseases: regulation, roles, and readjustment. Cancer Immunology, Immunotherapy, 68(4):673-685.
Kyburz, Andreas; Fallegger, Angela; Zhang, Xiaozhou; Altobelli, Aleksandra; Artola-Boran, Mariela; Borbet, Timothy; Urban, Sabine; Paul, Petra; Münz, Christian; Floess, Stefan; Huehn, Jochen; Cover, Timothy L; Blaser, Martin J; Taube, Christian; Müller, Anne (2019). Transmaternal Helicobacter pylori exposure reduces allergic airway inflammation in offspring through regulatory T cells. Journal of Allergy and Clinical Immunology, 143(4):1496-1512.e11.
Hutmacher, Cornelia; Núñez, Nicolás Gonzalo; Liuzzi, Anna Rita; Becher, Burkhard; Neri, Dario (2019). Targeted Delivery of IL2 to the Tumor Stroma Potentiates the Action of Immune Checkpoint Inhibitors by Preferential Activation of NK and CD8 T Cells. Cancer Immunology Research, 7(4):572-583.
Barnstorf, Isabel; Borsa, Mariana; Baumann, Nicolas; Pallmer, Katharina; Yermanos, Alexander; Joller, Nicole; Spörri, Roman; Welten, Suzanne P M; Kräutler, Nike J; Oxenius, Annette (2019). Chronic virus infection compromises memory bystander T cell function in an IL-6/STAT1-dependent manner. Journal of Experimental Medicine, 216(3):571-586.
Damania, Blossom; Münz, Christian (2019). Immunodeficiencies that predispose to pathologies by human oncogenic γ-herpesviruses. FEMS Microbiology Reviews, 43(2):181-192.
Sparber, Florian; De Gregorio, Corinne; Steckholzer, Simone; Ferreira, Filipa M; Dolowschiak, Tamas; Ruchti, Fiorella; Kirchner, Florian R; Mertens, Sarah; Prinz, Immo; Joller, Nicole; Buch, Thorsten; Glatz, Martin; Sallusto, Federica; LeibundGut-Landmann, Salomé (2019). The skin commensal yeast malassezia triggers a type 17 response that coordinates anti-fungal immunity and exacerbates skin inflammation. Cell Host & Microbe, 25(3):389-403.e6.
Rakebrandt, Nikolas Jan. Responses of CD4+ T Helper Cells and Regulatory T Cells During Heterologous Immune Challenge. 2019, University of Zurich, Faculty of Science.
Kirchner, Florian R; Littringer, Katharina; Altmeier, Simon; Tran, Van Du Thuong; Schönherr, Franziska; Lemberg, Christina; Pagni, Marco; Sanglard, Dominique; Joller, Nicole; LeibundGut-Landmann, Salomé (2019). Persistence of candida albicans in the oral mucosa induces a curbed inflammatory host response that is independent of immunosuppression. Frontiers in Immunology, 10:330.
Sheppard, Emily C; Rogers, Sally; Harmer, Nicholas J; Chahwan, Richard (2019). A universal fluorescence-based toolkit for real-time quantification of DNA and RNA nuclease activity. bioRxiv 548628, Cold Spring Harbor Laboratory.
Tugues, Sonia; Ducimetiere, Laura; Friebel, Ekaterina; Becher, Burkhard (2019). Innate lymphoid cells as regulators of the tumor microenvironment. Seminars in Immunology, 41:101270.
Galli, Edoardo; Friebel, Ekaterina; Ingelfinger, Florian; Unger, Susanne; Núñez, Nicolás Gonzalo; Becher, Burkhard (2019). The end of omics? High dimensional single cell analysis in precision medicine. European Journal of Immunology, 49(2):212-220.
Mundt, Sarah; Mrdjen, Dunja; Utz, Sebastian G; Greter, Melanie; Schreiner, Bettina; Becher, Burkhard (2019). Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation. Science Immunology, 4(31):1-10.
Murer, Anita; Rühl, Julia; Zbinden, Andrea; Capaul, Riccarda; Hammerschmidt, Wolfgang; Chijioke, Obinna; Münz, Christian (2019). MicroRNAs of Epstein-Barr Virus Attenuate T-Cell-Mediated Immune Control In Vivo. mBio, 10:e01941-18.
Nüesch, Ursina; Mauracher, Andrea A; Opitz, Lennart; Volkmer, Benjamin; Michalak-Mićka, Katarzyna; Kamarashev, Jivko; Hartwig, Tom; Reichmann, Ernst; Becher, Burkhard; Vavassori, Stefano; Pachlopnik Schmid, Jana (2019). Epithelial proliferation in inflammatory skin disease is regulated by tetratricopeptide repeat domain 7 (Ttc7) in fibroblasts and lymphocytes. Journal of Allergy and Clinical Immunology, 143(1):292-304.e8.
Schorer, Michelle; Kuchroo, Vijay K; Joller, Nicole (2019). Role of Co-stimulatory Molecules in T Helper Cell Differentiation. In: Azuma, Miyuki; Yagita, Hideo. Role of Co-stimulatory Molecules in T Helper Cell Differentiation. Singapore: Springer, 153-177.
Keller, Christian W; Münz, Christian; Lünemann, Jan D (2019). Autophagy in Autoimmunity. In: Rose, Noel; Mackay, Ian. The Autoimmune Diseases / 6th Edition. Amsterdam: Academic Press, 305-318.
Kotur, Monika Barbara. Autophagy protein-mediated antigen presentation during autoimmune CNS inflammation. 2019, University of Zurich, Faculty of Science.
Isringhausen, Stephan. Characterization and dynamics of hematopoietic bone marrow tissues during homeostasis and chronic infections. 2019, University of Zurich, Faculty of Science.
Spaccamela, Virginia Meda. Elucidating the pathophysiology of hyper-inflammation in the context of NADPH oxidase impairment. 2019, University of Zurich, Faculty of Science.
Vasilikos, Lazaros. Involvement of cellular inhibitor of apoptosis proteins (cIAPs) in tumor metastasis and hematopoietic stem cell differentiation & fitness. 2019, University of Zurich, Faculty of Science.
Loi, Monica; Ligeon, Laure-Anne; Münz, Christian (2019). MHC Class I Internalization via Autophagy Proteins. In: Ktistakis, Nicholas; Florey, Oliver. Autophagy. New York: Springer, 455-477.
Gannage, Monique; da Silva, Rosa Barreira; Münz, Christian (2019). Monitoring Antigen Processing for MHC Presentation via Macroautophagy. In: van Endert, Peter. Antigen Processing : Methods and Protocols. New York: Springer, 357-373.
Morrish, Rikke Brandstrup; Hermes, Michael; Metz, Jeremy; Stone, Nicholas; Pagliara, Stefano; Chahwan, Richard; Palombo, Francesca (2019). Single Cell Imaging of Nuclear Architecture Changes. Frontiers in Cell and Developmental Biology, 7:141.
Littringer, Katharina. Specialization and function of regulatory T cells during polarized immune responses. 2019, University of Zurich, Faculty of Science.
Tallón de Lara, Paulino. Spontaneous and therapy-induced control of disseminated cancer by t-cells. 2019, University of Zurich, Faculty of Science.
Utz, Sebastian G. The Development of Brain Macrophages and Their Requirement for TGF-β1. 2019, University of Zurich, Faculty of Science.
Delecluse, Susanne; Tsai, Ming-Han; Shumilov, Anatoliy; Bencun, Maja; Arrow, Sebastian; Beshirova, Aisha; Cottignies-Calamarte, Andréa; Lasitschka, Felix; Bulut, Olcay Cem; Münz, Christian; Zeier, Martin; Behrends, Uta; Delecluse, Henri-Jacques (2019). The Epstein-Barr virus induces the expression of the LPAM-1 integrin in B-cells in vitro and in vivo. Journal of Virology, 93(5):e01618-18.
Zdimerova, Hana. The Role of Multiple Sclerosis-Associated Genetic Risk Factors in Shaping Epstein-Barr Virus Specific Immune Control. 2019, University of Zurich, Faculty of Science.
Schweiger, Nicole Angelika. The role of immune cell populations in the therapeutic response to radiotherapy. 2019, University of Zurich, Faculty of Science.
Spilgies, Lisanne Madeline. The role of inhibitor of apoptosis proteins in inflammation. 2019, University of Zurich, Faculty of Science.
Schadt, Linda. Understanding the role of cancer-intrinsic cGAS expression in anticancer immunity and response to therapy. 2019, University of Zurich, Faculty of Science.
Tallón de Lara, Paulino; Cecconi, Virginia; Hiltbrunner, Stefanie; Yagita, Hideo; Friess, Martina; Bode, Beata; Opitz, Isabelle; Vrugt, Bart; Weder, Walter; Stolzmann, Paul; Felley-Bosco, Emanuela; Stahel, Rolf A; Tischler, Verena; Britschgi, Christian; Soldini, Davide; van den Broek, Maries; Curioni Fontecedro, Alessandra (2018). Gemcitabine synergizes with immune checkpoint inhibitors and overcomes resistance in a preclinical model and mesothelioma patients. Clinical Cancer Research, 24(24):6345-6354.
Tugues, Sonia; Amorim, Ana; Spath, Sabine; Martin-Blondel, Guillaume; Schreiner, Bettina; De Feo, Donatella; Lutz, Mirjam; Guscetti, Franco; Apostolova, Petya; Haftmann, Claudia; Hasselblatt, Peter; Núñez, Nicolás Gonzalo; Hottiger, Michael O; van den Broek, Maries; Manz, Markus G; Zeiser, Robert; Becher, Burkhard (2018). Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF–licensed myeloid cells. Science Translational Medicine, 10(469):eaat8410.
Rühl, Julia. Development of an Active EBV Vaccination Strategy Based on EBNA1-Specific T-Cell Immunity. 2018, University of Zurich, Faculty of Science.
Seyedsadr, Maryam S; Weinmann, Oliver; Amorim, Ana; Ineichen, Benjamin V; Egger, Matteo; Mirnajafi-Zadeh, Javad; Becher, Burkhard; Javan, Mohammad; Schwab, Martin E (2018). Inactivation of sphingosine-1-phosphate receptor 2 (S1PR2) decreases demyelination and enhances remyelination in animal models of multiple sclerosis. Neurobiology of Disease, 124:189-201.
Murer, Anita. Contribution of EBNA3 Oncogenes and Viral miRNAs to Epstein-Barr Virus Infection In vivo. 2018, University of Zurich, Faculty of Science.
Ligeon, Laure-Anne; Loi, Monica; Münz, Christian (2018). LC3-Associated Phagocytosis and Antigen Presentation. Current Protocols in Immunology, 123(1):e60.
Becker, Andrea C; Gannagé, Monique; Giese, Sebastian; Hu, Zehan; Abou-Eid, Shadi; Roubaty, Carole; Paul, Petra; Bühler, Lea; Gretzmeier, Christine; Dumit, Veronica I; Kaeser-Pebernard, Stéphanie; Schwemmle, Martin; Münz, Christian; Dengjel, Jörn (2018). Influenza A Virus Induces Autophagosomal Targeting of Ribosomal Proteins. Molecular & Cellular Proteomics, 17(10):1909-1921.
Latorre, Daniela; Kallweit, Ulf; Armentani, Eric; Foglierini, Mathilde; Mele, Federico; Cassotta, Antonino; Jovic, Sandra; Jarrossay, David; Mathis, Johannes; Zellini, Francesco; Becher, Burkhard; Lanzavecchia, Antonio; Khatami, Ramin; Manconi, Mauro; Tafti, Mehdi; Bassetti, Claudio L; Sallusto, Federica (2018). T cells in patients with narcolepsy target self-antigens of hypocretin neurons. Nature, 562(7725):63-68.
Gulati, Pratiksha; Rühl, Julia; Kannan, Abhilash; Pircher, Magdalena; Schuberth, Petra; Nytko, Katarzyna J; Pruschy, Martin; Sulser, Simon; Haefner, Mark; Jensen, Shawn; Soltermann, Alex; Jungraithmayr, Wolfgang; Eisenring, Maya; Winder, Thomas; Samaras, Panagiotis; Tabor, Annett; Stenger, Rene; Stupp, Roger; Weder, Walter; Renner, Christoph; Münz, Christian; Petrausch, Ulf (2018). Aberrant Lck Signal via CD28 Costimulation Augments Antigen-Specific Functionality and Tumor Control by Redirected T Cells with PD-1 Blockade in Humanized Mice. Clinical Cancer Research, 24(16):3981-3993.
Arnold, Isabelle C; Artola-Borán, Mariela; Tallón de Lara, Paulino; Kyburz, Andreas; Taube, Christian; Ottemann, Karen; van den Broek, Maries; Yousefi, Shida; Simon, Hans-Uwe; Müller, Anne (2018). Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. Journal of Experimental Medicine, 215(8):2055-2072.
Keller, Christian W; Loi, Monica; Ligeon, Laure-Anne; Gannagé, Monique; Lünemann, Jan D; Münz, Christian (2018). Endocytosis regulation by autophagy proteins in MHC restricted antigen presentation. Current Opinion in Immunology, 52:68-73.
Forconi, Catherine S; Cosgrove, Cormac P; Saikumar-Lakshmi, Pryia; Nixon, Christina E; Foley, Joslyn; Ong'echa, John Michael; Otieno, Juliana A; Alter, Galit; Münz, Christian; Moormann, Ann M (2018). Poorly cytotoxic terminally differentiated CD56CD16 NK cells accumulate in Kenyan children with Burkitt lymphomas. Blood Advances, 2(10):1101-1114.
Beffinger, Michal; Tallón de Lara, Paulino; Tugues, Sònia; Vermeer, Marijne; Montagnolo, Yannick; Ohs, Isabel; Cecconi, Virginia; Lucchiari, Giulia; Gagliardi, Aron; Misljencevic, Nikola; Sutton, James; Spörri, Roman; Becher, Burkhard; Gupta, Anurag; van den Broek, Maries (2018). CSF1R-dependent myeloid cells are required for NK‑mediated control of metastasis. Journal of Clinical Investigation Insight, 3(10):e97792.
Becher, Burkhard; Waisman, Ari; Lu, Li-Fan (2018). Conditional Gene-Targeting in Mice: Problems and Solutions. Immunity, 48(5):835-836.
Gradzka, Sylwia; Thomas, Oliver S; Kretz, Oliver; Haimovici, Aladin; Vasilikos, Lazaros; Wong, Wendy Wei-Lynn; Häcker, Georg; Gentle, Ian E (2018). Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes. Cell Death and Disease, 9(5):529.
Zimmerli, Dario; Cecconi, Virginia; Valenta, Tomas; Hausmann, George; Cantù, Claudio; Restivo, Gaetana; Hafner, Jürg; Basler, Konrad; van den Broek, Maries (2018). WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma. Oncogene, 37(27):3753-3762.
McHugh, Donal. Cooperation of the Epstein-Barr Virus with Kaposi Sarcoma associated Herpes Virus or the Human Immunodeficiency Virus enhances Viral Pathology in Vivo. 2018, University of Zurich, Faculty of Science.
Murer, Anita; McHugh, Donal; Caduff, Nicole; Kalchschmidt, Jens; Barros, Mario; Zbinden, Andrea; Capaul, Riccarda; Niedobitek, Gerald; Allday, Martin; Chijioke, Obinna; Münz, Christian (2018). EBV persistence without its EBNA3A and 3C oncogenes in vivo. PLoS Pathogens, 14(4):e1007039.
Mathew, Nimitha R; Baumgartner, Francis; Braun, Lukas; et al; Tugues, Sonia; Spath, Sabine; Becher, Burkhard (2018). Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nature Medicine, 24(3):282-291.
Wicki, Simone; Gurzeler, Ursina; Corazza, Nadia; Genitsch, Vera; Wong, Wendy Wei-Lynn; Kaufmann, Thomas (2018). Loss of BID Delays FASL-Induced Cell Death of Mouse Neutrophils and Aggravates DSS-Induced Weight Loss. International Journal of Molecular Sciences, 19(3):684.
Mrdjen, Dunja; Pavlovic, Anto; Hartmann, Felix J; Schreiner, Bettina; Utz, Sebastian G; Leung, Brian P; Lelios, Iva; Heppner, Frank L; Kipnis, Jonathan; Merkler, Doron; Greter, Melanie; Becher, Burkhard (2018). High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease. Immunity, 48(2):380-395.e6.
Thion, Morgane Sonia; et al; Buttgereit, Anne (2018). Microbiome influences prenatal and adult microglia in a sex-specific manner. Cell, 172(3):500-516.e16.
Cobos, Enrique J; Nickerson, Chelsea A; Gao, Fuying; Chandran, Vijayendran; Bravo-Caparrós, Inmaculada; González-Cano, Rafael; Riva, Priscilla; Andrews, Nick A; Latremoliere, Alban; Seehus, Corey R; Perazzoli, Gloria; Nieto, Francisco R; Joller, Nicole; Painter, Michio W; Ma, Chi Him Eddie; Omura, Takao; Chesler, Elissa J; Geschwind, Daniel H; Coppola, Giovanni; Rangachari, Manu; Woolf, Clifford J; Costigan, Michael (2018). Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling. Cell Reports, 22(5):1301-1312.
Siliņa, Karīna; Burkhardt, Chiara; Casanova, Ruben; Solterman, Alex; van den Broek, Maries (2018). A Quantitative Pathology Approach to Analyze the Development of Human Cancer-Associated Tertiary Lymphoid Structures. In: Dieu-Nosjean, Marie-Caroline. Tertiary Lymphoid Structures : Methods and Protocols. Switzerland: Springer, 71-86.
Mir, Mohsen Maleh. Anti-platelet therapy for metabolically induced nonalcoholic steatohepatitis and hepatocellular carcinoma. 2018, University of Zurich, Faculty of Science.
Deretic, Vojo; Prossnitz, Eric; Burge, Mark; Campen, Matthew J; Cannon, Judy; Liu, Ke Jian; Sklar, Larry A; et al; Münz, Christian (2018). Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations. Autophagy, 14(6):925-929.
Crnkovic, Martina Zarak. CD4⁺ cells : friend or foe in myocarditis? 2018, University of Zurich, Faculty of Science.
Littringer, Katharina; Moresi, Claudia; Rakebrandt, Nikolas; Zhou, Xiaobei; Schorer, Michelle; Dolowschiak, Tamas; Kirchner, Florian; Rost, Felix; Keller, Christian W; McHugh, Donal; LeibundGut-Landmann, Salomé; Robinson, Mark D; Joller, Nicole (2018). Common features of regulatory T cell specialization during Th1 responses. Frontiers in Immunology, 9:1344.
McHugh, Donal. Cooperation of the Epstein-Barr virus with Karposi sarcoma associated herpes virus or the human immunodeficiency virus enhances viral pathology in vivo. 2018, University of Zurich, Faculty of Science.
Zimmerli, Dario. Elucidating the roles of Wnt-secretion and β-catenin's interaction partners in development and disease. 2018, University of Zurich, Faculty of Science.
Amato, Maria Pia; Derfuss, Tobias; Hemmer, Bernard; Liblau, Roland; Montalban, Xavier; Soelberg Sørensen, Per; Miller, David H (2018). Environmental modifiable risk factors for multiple sclerosis: Report from the 2016 ECTRIMS focused workshop. Multiple Sclerosis, 24(5):590-603.
Sheppard, Emily C; Morrish, Rikke Brandstrup; Dillon, Michael J; Leyland, Rebecca; Chahwan, Richard (2018). Epigenomic Modifications Mediating Antibody Maturation. Frontiers in Immunology, 9:355.
Fahrny, Audrey. Exploring HIV latency and dissecting the contribution of APOBEC3G to HIV evolution using humanized mice models. 2018, University of Zurich, Faculty of Science.
Komuczki, Juliana Maria. Fate-map and reporter of GM-CSF mouse line reveals the role of GM-CSF in neuroinflammation. 2018, University of Zurich, Faculty of Science.
Dixon, Karen O; Schorer, Michelle; Nevin, James; Etminan, Yassaman; Amoozgar, Zohreh; Kondo, Takaaki; Kurtulus, Sema; Kassam, Nasim; Sobel, Raymond A; Fukumura, Dai; Jain, Rakesh K; Anderson, Ana C; Kuchroo, Vijay K; Joller, Nicole (2018). Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity. Journal of Immunology, 200(8):3000-3007.
Silina, Karina; Soltermann, Alex; Movahedian Attar, Farkhondeh; Casanova, Ruben; Uckeley, Zina M; Thut, Helen; Wandres, Muriel; Isajevs, Sergejs; Cheng, Phil; Curioni Fontecedro, Alessandra; Foukas, Periklis; Levesque, Mitchell P; Moch, Holger; Linē, Aija; van den Broek, Maries (2018). Germinal centers determine the prognostic relevance of tertiary lymphoid structures and are impaired by corticosteroids in lung squamous cell carcinoma. Cancer Research, 78(5):1308-1320.
Peschke, Benjamin. Glycan mediated immune responses in CNS autoimmunity. 2018, University of Zurich, Faculty of Science.
Mrdjen, Dunja. High-dimensional mapping of the immune atlas in the central nervous system during health, aging and disease. 2018, University of Zurich, Faculty of Science.
Krieg, Carsten; Nowicka, Malgorzata; Guglietta, Silvia; Schindler, Sabrina; Hartmann, Felix J; Weber, Lukas M; Dummer, Reinhard; Robinson, Mark D; Levesque, Mitchell P; Becher, Burkhard (2018). High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy. Nature Medicine, 24(2):144-153.
Münz, Christian (2018). Human γ-Herpesvirus Infection, Tumorigenesis, and Immune Control in Mice with Reconstituted Human Immune System Components. Frontiers in Immunology, 9:238.
Tušup, Marina. Immunomodulation by RNA. 2018, University of Zurich, Faculty of Science.
Leung, Carol; Münz, Christian; Riemer, Angelika (2018). Immunotherapy and Vaccine Development. Journal of Immunology Research, 2018:8751027.
Sparber, Florian; Dolowschiak, Tamas; Mertens, Sarah; Lauener, Laura; Clausen, Björn E; Joller, Nicole; Stoitzner, Patrizia; Tussiwand, Roxane; LeibundGut-Landmann, Salomé (2018). Langerin+ DCs regulate innate IL-17 production in the oral mucosa during Candida albicans-mediated infection. PLoS Pathogens, 14(5):e1007069.
Loi, Monica. Macroautophagy in major histocampatibility complex (MHC) class I-restricted antigen presentation. 2018, University of Zurich, Faculty of Science.
Posch, Florian; Silina, Karina; Leibl, Sebastian; Mündlein, Axel; Moch, Holger; Siebenhüner, Alexander; Samaras, Panagiotis; Riedl, Jakob; Stotz, Michael; Szkandera, Joanna; Stöger, Herbert; Pichler, Martin; Stupp, Roger; van den Broek, Maries; Schraml, Peter; Gerger, Armin; Petrausch, Ulf; Winder, Thomas (2018). Maturation of tertiary lymphoid structures and recurrence of stage II and III colorectal cancer. OncoImmunology, 7(2):e1378844.
D'Agati, Gianluca. Modeling of developmental and tumorigenic lesions of the zebrafish notochord. 2018, University of Zurich, Faculty of Science.
Crameri, Michel; Bauer, Michael; Caduff, Nicole; Walker, Raphael; Steiner, Fiona; Franzoso, Francesca D; Gujer, Cornelia; Boucke, Karin; Kucera, Talissa; Zbinden, Andrea; Münz, Christian; Fraefel, Cornel; Greber, Urs F; Pavlovic, Jovan (2018). MxB is an interferon-induced restriction factor of human herpesviruses. Nature Communications, 9(1):1980.
Münz, Christian (2018). Non-canonical Functions of Macroautophagy Proteins During Endocytosis by Myeloid Antigen Presenting Cells. Frontiers in Immunology, 9:2765.
Delaunay, Tiphaine; Violland, Mathilde; Boisgerault, Nicolas; Dutoit, Soizic; Vignard, Virginie; Münz, Christian; Gannage, Monique; Dréno, Brigitte; Vaivode, Kristine; Pjanova, Dace; Labarrière, Nathalie; Wang, Yaohe; Chiocca, E Antonio; Boeuf, Fabrice Le; Bell, John C; Erbs, Philippe; Tangy, Frédéric; Grégoire, Marc; Fonteneau, Jean-François (2018). Oncolytic viruses sensitize human tumor cells for NY-ESO-1 tumor antigen recognition by CD4+ effector T cells. OncoImmunology, 7(3):e1407897.
Yu, Xueyang. The cytokine TGF-β promotes the development and homeostasis of alveolar macrophages. 2018, University of Zurich, Faculty of Science.
Knop, Janin. The role of TNFR2 and IAPs in the regulation of cell death and hematopoiesis. 2018, University of Zurich, Faculty of Science.
Hartwig, Tom. The role of regulatory and γδ T cells in the formation of chronic and relapsing psoriasiform skin lesions. 2018, University of Zurich, Faculty of Science.
Vrohlings, Melissa. Unraveling the mechanism of IL-12 mediated glioma rejection. 2018, University of Zurich, Faculty of Science.
Ohs, Isabel; Ducimetière, Laura; Marinho, Joana; Kulig, Paulina; Becher, Burkhard; Tugues, Sonia (2017). Restoration of natural killer cell antimetastatic activity by IL12 and checkpoint blockade. Cancer Research, 77(24):7059-7071.
Keller, Christian W; Sina, Christina; Kotur, Monika B; Ramelli, Giulia; Mundt, Sarah; Quast, Isaak; Ligeon, Laure-Anne; Weber, Patrick; Becher, Burkhard; Münz, Christian; Lünemann, Jan D (2017). ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4+ T cell pathogenicity during CNS inflammation. Proceedings of the National Academy of Sciences of the United States of America, 114(52):E11228-E11237.
Casella, Giacomo; Finardi, Annamaria; Descamps, Hélène; Colombo, Federico; Maiorino, Chiara; Ruffini, Francesca; Patrone, Marco; Degano, Massimo; Martino, Gianvito; Muzio, Luca; Becher, Burkhard; Furlan, Roberto (2017). IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression. Scientific Reports, 7(1):16547.
Yu, Xueyang; Buttgereit, Anne; Lelios, Iva; Utz, Sebastian G; Cansever, Dilay; Becher, Burkhard; Greter, Melanie (2017). The cytokine TGF-β promotes the development and homeostasis of alveolar macrophages. Immunity, 47(5):903-912.e4.
Anzai, Atsushi; Choi, Jennifer L; He, Shun; Fenn, Ashley M; Nairz, Manfred; Rattik, Sara; McAlpine, Cameron S; Mindur, John E; Chan, Christopher T; Iwamoto, Yoshiko; Tricot, Benoit; Wojtkiewicz, Gregory R; Weissleder, Ralph; Libby, Peter; Nahrendorf, Matthias; Stone, James R; Becher, Burkhard; Swirski, Filip K (2017). The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes. Journal of Experimental Medicine, 214(11):3293-3310.
De Feo, Donatella; Merlini, Arianna; Brambilla, Elena; Ottoboni, Linda; Laterza, Cecilia; Menon, Ramesh; Srinivasan, Sundararajan; Farina, Cinthia; Garcia Manteiga, Jose Manuel; Butti, Erica; Bacigaluppi, Marco; Comi, Giancarlo; Greter, Melanie; Martino, Gianvito (2017). Neural precursor cell-secreted TGF-β2 redirects inflammatory monocyte-derived cells in CNS autoimmunity. Journal of Clinical Investigation, 127(11):3937-3953.
Willrodt, Ann-Helen; Beffinger, Michal; Vranova, Martina; Protsyuk, Darya; Schuler, Katja; Jadhav, Maria; Heikenwalder, Mathias; van den Broek, Maries; Borsig, Lubor; Halin, Cornelia (2017). Stromal Expression of Activated Leukocyte Cell Adhesion Molecule Promotes Lung Tumor Growth and Metastasis. American Journal of Pathology, 187(11):2558-2569.
Lysenko, Veronika; McHugh, Donal; Behrmann, Lena; Rochat, Mary-Aude; Wilk, Christian M; Kovtonyuk, Larisa V; Bourquin, Jean-Pierre; Münz, Christian; Manz, Markus G; Speck, Roberto F; Theocharides, Alexandre P (2017). Humanised mouse models for haematopoiesis and infectious diseases. Swiss Medical Weekly, 147:w14516.
Münz, Christian (2017). Autophagy Proteins in Viral Exocytosis and Anti-Viral Immune Responses. Viruses, 9(10):E288.
Chatterjee, Bithi; Sahli, Laura; Chijioke, Obinna; Went, Philip; Münz, Christian; Trojan, Andreas (2017). An immunocompetent patient with a recurrence-free Epstein-Barr virus positive plasmacytoma possesses robust Epstein-Barr virus specific T-cell responses. Haematologica, 102(10):e419-e422.
Cossarizza, Andrea; Chang, Hyun-Dong; Radbruch, Andreas; Akdis, Mübeccel; et al; Becher, Burkhard; Engelhardt, B; LeibundGut-Landmann, Salomé; Ludewig, B; Oxenius, Annette (2017). Guidelines for the use of flow cytometry and cell sorting in immunological studies. European Journal of Immunology, 47(10):1584-1797.
Nussbaum, Kathrin; Burkhard, Sara H; Ohs, Isabel; Mair, Florian; Klose, Christoph S N; Arnold, Sebastian J; Diefenbach, Andreas; Tugues, Sonia; Becher, Burkhard (2017). Tissue microenvironment dictates the fate and tumor-suppressive function of type 3 ILCs. Journal of Experimental Medicine, 214(8):2331-2347.
Curioni-Fontecedro, Alessandra; Ickenberg, C; Franzen, D; Rogler, Gerhard; Burger, Irene A; van den Broek, M (2017). Diffuse pseudoprogression in a patient with metastatic non-small-cell lung cancer treated with Nivolumab. Annals of Oncology, 28(8):2040-2041.
Münz, Christian (2017). Humanized mouse models for Epstein Barr virus infection. Current Opinion in Virology, 25:113-118.
Onder, Lucas; Mörbe, Urs; Pikor, Natalia; Novkovic, Mario; Cheng, Hung-Wei; Hehlgans, Thomas; Pfeffer, Klaus; Becher, Burkhard; Waisman, Ari; Rülicke, Thomas; Gommerman, Jennifer; Mueller, Christopher G; Sawa, Shinichiro; Scandella, Elke; Ludewig, Burkhard (2017). Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis. Immunity, 47(1):80-92.e4.
Galluzzi, Lorenzo; et al; Ballabio, Andrea; Boya, Patricia; Cuervo, Ana Maria; Deretic, Vojo; Dikic, Ivan; Jäättelä, Marja; Johansen, Terje; Juhasz, Gabor; Kraft, Claudine; Levine, Beth; Münz, Christian (2017). Molecular definitions of autophagy and related processes. The EMBO Journal, 36(13):1811-1836.
McHugh, Donal; Caduff, Nicole; Barros, Mario Henrique M; Rämer, Patrick C; Raykova, Ana; Murer, Anita; Landtwing, Vanessa; Quast, Isaak; Styles, Christine T; Spohn, Michael; Fowotade, Adeola; Delecluse, Henri-Jacques; Papoudou-Bai, Alexandra; Lee, Yong-Moon; Kim, Jin-Man; Middeldorp, Jaap; Schulz, Thomas F; Cesarman, Ethel; Zbinden, Andrea; Capaul, Riccarda; White, Robert E; Allday, Martin J; Niedobitek, Gerald; Blackbourn, David J; Grundhoff, A; Münz, Christian (2017). Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression. Cell Host & Microbe, 22(1):61-73.
Djaoud, Zakia; Guethlein, Lisbeth A; Horowitz, Amir; Azzi, Tarik; Nemat-Gorgani, Neda; Olive, Daniel; Nadal, David; Norman, Paul J; Münz, Christian; Parham, Peter (2017). Two alternate strategies for innate immunity to Epstein-Barr virus: one using NK cells and the other NK cells and γδ T cells. Journal of Experimental Medicine, 214(6):1827-1841.
Gretzmeier, Christine; Eiselein, Sven; Johnson, Gregory R; Engelke, Rudolf; Nowag, Heike; Zarei, Mostafa; Küttner, Victoria; Becker, Andrea C; Rigbolt, Kristoffer T G; Høyer-Hansen, Maria; Andersen, Jens S; Münz, Christian; Murphy, Robert F; Dengjel, Jörn (2017). Degradation of protein translation machinery by amino acid starvation-induced macroautophagy. Autophagy, 13(6):1064-1075.
Keller, Christian W; Loi, Monica; Ewert, Svenja; Quast, Isaak; Theiler, Romina; Gannagé, Monique; Münz, Christian; De Libero, Gennaro; Freigang, Stefan; Lünemann, Jan D (2017). The autophagy machinery restrains iNKT cell activation through CD1D1 internalization. Autophagy, 13(6):1025-1036.
Keller, Christian. Non-Canonical Functions of the Essential Autophagy Protein ATG5 in Antigen Processing and Presentation. 2017, University of Zurich, Faculty of Medicine.
Chevrier, Stéphane; Levine, Jacob Harrison; Zanotelli, Vito R T; Silina, Karina; Schulz, Daniel; Bacac, Marina; Ries, Carola Hermine; Ailles, Laurie; Jewett, Michael Alexander Spencer; Moch, Holger; van den Broek, Maries; Beisel, Christian; Stadler, Michael Beda; Gedye, Craig; Reis, Bernhard; Pe'er, Dana; Bodenmiller, Bernd (2017). An Immune Atlas of Clear Cell Renal Cell Carcinoma. Cell, 169(4):736-749.e18.
Spath, Sabine; Komuczki, Juliana; Hermann, Mario; Pelczar, Pawel; Mair, Florian; Schreiner, Bettina; Becher, Burkhard (2017). Dysregulation of the Cytokine GM-CSF Induces Spontaneous Phagocyte Invasion and Immunopathology in the Central Nervous System. Immunity, 46(2):245-260.
Vavricka, Stephan; Ruiz, Pedro A; Scharl, Sylvie; Biedermann, Luc; Scharl, Michael; de Vallière, Cheryl; Lundby, Carsten; Wenger, Roland H; Held, Leonhard; Merz, Tobias M; Gassmann, Max; Lutz, Thomas; Kunz, Andres; Bron, Denis; Fontana, Adriano; Strauss, Laura; Weber, Achim; Fried, Michael; Rogler, Gerhard; Zeitz, Jonas (2017). Protocol for a prospective, controlled, observational study to evaluate the influence of hypoxia on healthy volunteers and patients with inflammatory bowel disease: the Altitude IBD Study. BMJ Open, 7(1):e013477.
Vasilikos, Lazaros; Spilgies, Lisanne M; Knop, J; Wong, W Wei-Lynn (2017). Regulating the balance between necroptosis, apoptosis and inflammation by inhibitors of apoptosis proteins. Immunology and Cell Biology, 95(2):160-165.
Becher, Burkhard; Spath, Sabine; Goverman, Joan (2017). Cytokine networks in neuroinflammation. Nature Reviews. Immunology, 17(1):49-59.
Mordasini, Vanessa. Activation of ATR-Chk1 pathway facilitates EBV-mediated transformation of primary tonsillar B-cells. 2017, University of Zurich, Faculty of Science.
Gulati, Pratiksha. Adoptive therapy with T-cells genetically targeted to tumor associated antigen through the introduction of chimeric antigen receptors (CARs). 2017, University of Zurich, Faculty of Science.
Ligeon, Laure-Anne; Romao, Susana; Münz, Christian (2017). Analysis of LC3-associated phagocytosis and antigen presentation. In: Botelho, Roberto. Phagocytosis and Phagosomes. New York: Springer, 145-168.
Münz, Christian (2017). Autophagy Proteins in Phagocyte Endocytosis and Exocytosis. Frontiers in Immunology, 8:1183.
Tanzer, Maria C; Khan, Nufail; Rickard, James A; Etemadi, Nima; Lalaoui, Najoua; Spall, Sukhdeep Kaur; Hildebrand, Joanne M; Segal, David; Miasari, Maria; Chau, Diep; Wong, WendyWei-Lynn; McKinlay, Mark; Chunduru, Srinivas K; Benetatos, Christopher A; Condon, Stephen M; Vince, James E; Herold, Marco J; Silke, John (2017). Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways. Cell Death and Differentiation, 24(3):481-491.
Nowicka, Malgorzata; Krieg, Carsten; Weber, Lukas M; Hartmann, Felix J; Guglietta, Silvia; Becher, Burkhard; Levesque, Mitchell P; Robinson, Mark D (2017). CyTOF workflow: differential discovery in high-throughput high-dimensional cytometry datasets. F1000Research, 6:748.
Münz, Christian (2017). Epstein-Barr Virus-Specific Immune Control by Innate Lymphocytes. Frontiers in Immunology, 8:1658.
Mrdjen, Dunja; Hartmann, Felix J; Becher, Burkhard (2017). High Dimensional Cytometry of Central Nervous System Leukocytes During Neuroinflammation. Methods in Molecular Biology, 1559:321-332.
Schmidt, Karsten; Wienken, Magdalena; Keller, Christian W; Balcarek, Peter; Münz, Christian; Schmidt, Jens (2017). IL-1β-Induced Accumulation of Amyloid: Macroautophagy in Skeletal Muscle Depends on ERK. Mediators of Inflammation, (2017):5470831.
Grabinger, T; Bode, K J; Demgenski, J; Seitz, C; Delgado, M E; Kostadinova, F; Reinhold, C; Etemadi, N; Wilhelm, S; Schweinlin, M; Hänggi, Kay; Knop, J; Hauck, C; Walles, H; Silke, J; Wajant, H; Nachbur, U; Wong, W Wei-Lynn; Brunner, T (2017). Inhibitor of apoptosis protein-1 regulates tumor necrosis factor-mediated destruction of intestinal epithelial cells. Gastroenterology, 152(4):867-879.
Raykova, Ana; Carrega, Paolo; Lehmann, Frank M; Ivanek, Robert; Landtwing, Vanessa; Quast, Isaak; Lünemann, Jan D; Finke, Daniela; Ferlazzo, Guido; Chijioke, Obinna; Münz, Christian (2017). Interleukins 12 and 15 induce cytotoxicity and early NK-cell differentiation in type 3 innate lymphoid cells. Blood Advances, 1(27):2679-2691.
Loi, Monica. Macroautophagy in Major Histocompatibility Complex (MHC) class I-restricted Antigen Presentation. 2017, University of Zurich, Faculty of Science.
Münz, Christian; Chijioke, Obinna (2017). Natural killer cells in herpesvirus infections. F1000Research, 6:1231.
Ros, Uris; Peña-Blanco, Aida; Hänggi, Kay; Kunzendorf, Ulrich; Krautwald, Stefan; Wong, W Wei-Lynn; García-Sáez, Ana J (2017). Necroptosis execution is mediated by plasma membrane nanopores independent of calcium. Cell Reports, 19(1):175-187.
Hänggi, Kay; Vasilikos, Lazaros; Valls, Aida Freire; Yerbes, Rosario; Knop, Janin; Spilgies, Lisanne M; Rieck, Kristy; Misra, Tvisha; Bertin, John; Gough, Peter J; Schmidt, Thomas; de Almodòvar, Carmen Ruiz; Wong, W Wei-Lynn (2017). RIPK1/RIPK3 promotes vascular permeability to allow tumor cell extravasation independent of its necroptotic function. Cell Death and Disease, 8(2):e2588.
Buttgereit, Anne. Sall1 is a transcriptional regulator defining microglia identity and function. 2017, University of Zurich, Faculty of Science.
Mangani, Davide. Targeting the vascular and immunosuppressive networks in glioblastoma. 2017, University of Zurich, Faculty of Science.
Münz, Christian (2017). The Autophagic Machinery in Viral Exocytosis. Frontiers in Microbiology, 8:269.
Hänggi, K. The Role of Inhibitor of Apoptosis Proteins (IAPs) and Receptor Interacting Protein Kinases (RIPKs) in Cancer. 2017, University of Zurich, Faculty of Medicine.
Münz, Christian (2017). The macroautophagy machinery in endo- and exocytosis. Journal of Molecular Biology, 429(4):473-485.
Koller, Andreas; Bianchini, Rodolfo; Schlager, Sandra; Münz, Christian; Kofler, Barbara; Wiesmayr, Silke (2017). The neuropeptide galanin modulates natural killer cell function. Neuropeptides, 64:109-115.
Fenini, Gabriele. The role of mitogen-activated protein kinases in inflammasome activation. 2017, University of Zurich, Faculty of Science.
Joller, Nicole; Kuchroo, Vijay K (2017). Tim-3, Lag-3, and TIGIT. In: Yoshimura, Akihiko. Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity. Cham: Springer, 127-156.
Raykova, Ana. Type 3 Innate Lymphoid Cells Acquire a Cytotoxic Program upon Stimulation with Interleukins 12 and 15. 2017, University of Zurich, Faculty of Science.
Buttgereit, Anne; Lelios, Iva; Yu, Xueyang; Vrohlings, Melissa; Krakoski, Natalie R; Gautier, Emmanuel L; Nishinakamura, Ryuichi; Becher, Burkhard; Greter, Melanie (2016). Sall1 is a transcriptional regulator defining microglia identity and function. Nature Immunology, 17(12):1397-1406.
Becher, Burkhard; Tugues, Sonia; Greter, Melanie (2016). GM-CSF: from growth factor to central mediator of tissue inflammation. Immunity, 45(5):963-973.
Hartmann, Felix J; Bernard-Valnet, Raphaël; Quériault, Clémence; Mrdjen, Dunja; Weber, Lukas M; Galli, Edoardo; Krieg, Carsten; Robinson, Mark D; Nguyen, Xuan-Hung; Dauvilliers, Yves; Liblau, Roland S; Becher, Burkhard (2016). High-dimensional single-cell analysis reveals the immune signature of narcolepsy. Journal of Experimental Medicine, 213(12):2621-2633.
Landtwing, Vanessa; Raykova, Ana; Pezzino, Gaetana; Béziat, Vivien; Marcenaro, Emanuela; Graf, Claudine; Moretta, Alessandro; Capaul, Riccarda; Zbinden, Andrea; Ferlazzo, Guido; Malmberg, Karl-Johan; Chijioke, Obinna; Münz, Christian (2016). Cognate HLA absence in trans diminishes human NK cell education. Journal of Clinical Investigation, 126(10):3772-3782.
Aden, Konrad; Rehman, Ateequr; Falk-Paulsen, Maren; Secher, Thomas; Kuiper, Jan; Tran, Florian; Pfeuffer, Steffen; Sheibani-Tezerji, Raheleh; Breuer, Alexandra; Luzius, Anne; Jentzsch, Marlene; Häsler, Robert; Billmann-Born, Susanne; Will, Olga; Lipinski, Simone; Bharti, Richa; Adolph, Timon; Iovanna, Juan L; Kempster, Sarah L; Blumberg, Richard S; Schreiber, Stefan; Becher, Burkhard; Chamaillard, Mathias; Kaser, Arthur; Rosenstiel, Philip (2016). Epithelial IL-23R signaling licenses protective IL-22 responses in intestinal inflammation. Cell Reports, 16(8):2208-2218.
Harmer, Nicholas J; Chahwan, Richard (2016). Isotype switching: Mouse IgG3 constant region drives increased affinity for polysaccharide antigens. Virulence, 7(6):623-626.
Parsa, Roham; Lund, Harald; Georgoudaki, Anna-Maria; Zhang, Xing-Mei; Guerreiro-Cacais, André Ortlieb; Grommisch, David; Warnecke, Andreas; Croxford, Andrew L; Jagodic, Maja; Becher, Burkhard; Karlsson, Mikael C I; Harris, Robert A (2016). BAFF-secreting neutrophils drive plasma cell responses during emergency granulopoiesis. Journal of Experimental Medicine, 213(8):1537-1553.
Landtwing, Vanessa. Natural Killer Cell: Repertoire Development, Education and Activation. 2016, University of Zurich, Faculty of Science.
Walker, Lucy S K; Ziegler, Steven; Becher, Burkhard (2016). Contemplating autoimmunity in the Aegean islands. Nature Immunology, 17(3):218-220.
Fonteneau, Jean Francois; Brilot, Fabienne; Münz, Christian; Gannagé, Monique (2016). The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4+ T Cells after Intercellular Antigen Transfer. Journal of Immunology, 196(1):64-71.
Kulig, Paulina; Burkhard, Sara; Mikita-Geoffroy, Joanna; Croxford, Andrew L; Hövelmeyer, Nadine; Gyülveszi, Gabor; Gorzelanny, Christian; Waisman, Ari; Borsig, Lubor; Becher, Burkhard (2016). IL-17A mediated endothelial breach promotes metastasis formation. Cancer immunology research, 4(1):26-32.
Amini, Poorya; Stojkov, Darko; Wang, Xiaoliang; Wicki, Simone; Kaufmann, Thomas; Wong, Wendy Wei-Lynn; Simon, Hans-Uwe; Yousefi, Shida (2016). NET formation can occur independently of RIPK3 and MLKL signaling. European Journal of Immunology, 46(1):178-184.
Mair, Florian; Hartmann, Felix J; Mrdjen, Dunja; Tosevski, Vinko; Krieg, Carsten; Becher, Burkhard (2016). The end of gating? An introduction to automated analysis of high dimensional cytometry data. European Journal of Immunology, 46(1):34-43.
Loi, Monica; Gannagé, Monique; Münz, Christian (2016). ATGs help MHC class II, but inhibit MHC class I antigen presentation. Autophagy, 12(9):1681-1682.
Paul, P; Münz, C (2016). Autophagy and mammalian viruses: roles in immune response, viral replication, and beyond. In: Kielian, Margaret; Maramorosch, Karl; Mettenleiter, Thomas. Advances in Virus Research. Burlington: Elsevier, 149-195.
Münz, Christian (2016). Autophagy beyond intracellular MHC Class II antigen presentation. Trends in Immunology, 37(11):755-763.
Münz, Christian (2016). Autophagy proteins in antigen processing for presentation on MHC molecules. Immunological Reviews, 272(1):17-27.
Sellés Moreno, Carla. Clock gene dysregulation and nuclear receptor expression in DSS-induced colitis. 2016, University of Zurich, Faculty of Science.
Spalinger, Marianne R; Kasper, Stephanie; Gottier, Claudia; Lang, Silvia; Atrott, Kirstin; Vavricka, Stephan R; Scharl, Sylvie; Raselli, Tina; Frey-Wagner, Isabelle; Gutte, Petrus M; Grütter, Markus G; Beer, Hans-Dietmar; Contassot, Emmanuel; Chan, Andrew C; Dai, Xuezhi; Rawlings, David J; Mair, Florian; Becher, Burkhard; Falk, Werner; Fried, Michael; Rogler, Gerhard; Scharl, Michael (2016). Corrigendum - NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22. Journal of Clinical Investigation, 126(11):4388.
Münz, Christian (2016). Dengue virus: protection by t cells, disease exacerbation by antibodies? EBioMedicine, 13:23-24.
Moormann, Ann; Münz, Christian (2016). Editorial overview: Viruses and cancer. Current Opinion in Virology, 20:iv-v.
Münz, Christian (2016). Epstein Barr virus: a tumor virus that needs cytotoxic lymphocytes to persist asymptomatically. Current Opinion in Virology, 20:34-39.
Wang, Shanzhi; Chahwan, Richard; Wei, Lirong; Scharff, Matthew D (2016). Error-Prone Mismatch and Base Excision DNA Repair in Somatic Hypermutation. In: Ratcliffe, M J H. Encyclopedia of Immunobiology. Canada: Elsevier, 126-133.
Greter, Melanie (2016). Family ties among CNS macrophages. Nature Immunology, 17(7):742-743.
Klionsky, Daniel J; Abdelmohsen, Kotb; Abe, Akihisa; Abedin, Md Joynal; Abeliovich, Hagai; Acevedo Arozena, Abraham; Adachi, Hiroaki; Adams, Christopher M; Adams, Peter D; Adeli, Khosrow; Adhihetty, Peter J; Adler, Sharon G; Agam, Galila; Agarwal, Rajesh; Aghi, Manish K; Agnello, Maria; Agostinis, Patrizia; Aguilar, Patricia V; Aguirre-Ghiso, Julio; Airoldi, Edoardo M; Ait-Si-Ali, Slimane; Akematsu, Takahiko; Akporiaye, Emmanuel T; Al-Rubeai, Mohamed; Albaiceta, Guillermo M; Albanese, Chris; Albani, Diego; Albert, Matthew L; Aldudo, Jesus; Algül, Hana; et al (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1):1-222.
Kulig, P; Musiol, S; Freiberger, S N; Schreiner, B; Gyülveszi, G; Russo, G; Pantelyushin, S; Kishihara, K; Alessandrini, F; Kündig, T; Sallusto, F; Hofbauer, G F L; Haak, S; Becher, B (2016). IL-12 protects from psoriasiform skin inflammation. Nature Communications, 7:13466.
Beffinger, Michal. Immunotherapy of metastatic disease. 2016, University of Zurich, Faculty of Science.
Kakalacheva, Kristina; Regenass, Stephan; Wiesmayr, Silke; Azzi, Tarik; Berger, Christoph; Dale, Russell; Brilot, Fabienne; Münz, Christian; Rostasy, Kevin; Nadal, David; Lünemann, Jan (2016). Infectious Mononucleosis Triggers Generation of IgG Auto-Antibodies against Native Myelin Oligodendrocyte Glycoprotein. Viruses, 8(2):51.
Ohs, Isabel; van den Broek, Maries; Nussbaum, Kathrin; Münz, Christian; Arnold, Sebastian J; Quezada, Sergio A; Tugues, Sonia; Becher, Burkhard (2016). Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis. Nature Communications, 7:13708.
Anderson, Ana C; Joller, Nicole; Kuchroo, Vijay K (2016). Lag-3, Tim-3, and TIGIT: Co-inhibitory receptors with specialized functions in immune regulation. Immunity, 44(5):989-1004.
Wicki, S; Gurzeler, U; Wong, W Wei-Lynn; Jost, P J; Bachmann, D; Kaufmann, T (2016). Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils. Cell Death and Disease, 7(10):e2422.
Loi, Monica; Müller, Anne; Steinbach, Karin; Niven, Jennifer; Barreira da Silva, Rosa; Paul, Petra; Ligeon, Laure-Anne; Caruso, Assunta; Albrecht, Randy A; Becker, Andrea C; Annaheim, Nicolas; Nowag, Heike; Dengjel, Jörn; García-Sastre, Adolfo; Merkler, Doron; Münz, Christian; Gannagé, Monique (2016). Macroautophagy proteins control MHC class I levels on dendritic cells and shape anti-viral CD8+ T cell responses. Cell Reports, 15(5):1076-1087.
Chijioke, Obinna; Landtwing, Vanessa; Münz, Christian (2016). NK cell influence on the outcome of primary epstein-barr virus infection. Frontiers in Immunology, 7:323.
Ferreira-Teixeira, Margarida; Paiva-Oliveira, Daniela; Parada, Belmiro; Alves, Vera; Sousa, Vitor; Chijioke, Obinna; Münz, Christian; Reis, Flávio; Rodrigues-Santos, Paulo; Gomes, Célia (2016). Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells. BMC Medicine, 14:163.
Jerg Hartmann, Felix. Pathogenic mediators in multiple sclerosis: GM-CSF and other TH cell-derived cytokines. 2016, University of Zurich, Faculty of Science.
Kishi, Yasuhiro; Kondo, Takaaki; Xiao, Sheng; Yosef, Nir; Gaublomme, Jellert; Wu, Chuan; Wang, Chao; Chihara, Norio; Regev, Aviv; Joller, Nicole; Kuchroo, Vijay K (2016). Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity. Journal of Experimental Medicine, 213(11):2489-2501.
Parsons, Emily; Otieno, Juliana A; Ong'echa, John Michael; Nixon, Christina E; Vulule, John; Münz, Christian; Stewart, V Ann; Moormann, Ann M (2016). Regulatory T cells in endemic burkitt lymphoma patients are associated with poor outcomes: a prospective, longitudinal study. PLoS ONE, 11(12):e0167841.
Rakebrandt, N; Littringer, K; Joller, N (2016). Regulatory T cells: balancing protection versus pathology. Swiss Medical Weekly, 146:14343.
Beil-Wagner, Jane; Dössinger, Georg; Schober, Kilian; vom Berg, Johannes; Tresch, Achim; Grandl, Martina; Palle, Pushpalatha; Mair, Florian; Gerhard, Markus; Becher, Burkhard; Busch, Dirk H; Buch, Thorsten (2016). T cell-specific inactivation of mouse CD2 by CRISPR/Cas9. Scientific Reports, 6:21377.
Lalaoui, N; Hänggi, K; Brumatti, G; Chau, D; Nguyen, N Y N; Vasilikos, L; Spilgies, L M; Heckmann, D A; Ma, C; Ghisi, M; Salmon, J M; Matthews, G M; de Valle, E; Moujalled, D M; Menon, M B; Spall, S K; Glaser, S P; Richmond, J; Lock, R B; Condon, S M; Gugasyan, R; Gaestel, M; Guthridge, M; Johnstone, R W; Munoz, L; Wei, A; Ekert, P G; Vaux, D L; Wong, W Wei-Lynn; Silke, J (2016). Targeting p38 or MK2 enhances the anti-leukemic activity of smac-mimetics. Cancer Cell, 29(2):145-158.
Etemadi, N; Chopin, M; Anderton, H; Tanzer, M C; Rickard, J A; Abeysekera, W; Hall, C; Spall, S K; Wang, B; Xiong, Y; HLa, T; Pitson, S M; Bonder, C S; Wong, W W-L; Ernst, M; Smyth, G K; Vaux, D L; Nutt, S L; Nachbur, U; Silke, J (2015). TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase-1. eLife, 4:e10592.
Münz, Christian (2015). Live Long and Prosper for Antigen Cross-Presentation. Immunity, 43(6):1028-1030.
Becher, Burkhard (2015). The good, the bad, or the pretty: IL-17 builds lymphoid tissues in the brain. Immunity, 43(6):1033-1034.
Romao, Susana; Puente, Emilio Tejera; Nytko, Katarzyna J; Siler, Ulrich; Münz, Christian; Reichenbach, Janine (2015). Defective nuclear entry of hydrolases prevents neutrophil extracellular trap formation in patients with chronic granulomatous disease. Journal of Allergy and Clinical Immunology, 136(6):1703-1706.e5.
Boutaffala, L; Bertrand, M J M; Remouchamps, C; et al (2015). NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis. Cell Death and Differentiation, 22(12):2020-2033.
Gregorovic, Goran; Boulden, Elizabeth A; Bosshard, Rachel; Elgueta Karstegl, Claudio; Skalsky, Rebecca; Cullen, Bryan R; Gujer, Cornelia; Rämer, Patrick; Münz, Christian; Farrell, Paul J (2015). Epstein-barr viruses (EBVs) deficient in EBV-encoded RNAs have higher levels of latent membrane protein 2 RNA expression in lymphoblastoid cell lines and efficiently establish persistent infections in humanized mice. Journal of Virology, 89(22):11711-11714.
Kreibich, Saskia; Emmenlauer, Mario; Fredlund, Jennifer; Rämö, Pauli; Münz, Christian; Dehio, Christoph; Enninga, Jost; Hardt, Wolf-Dietrich (2015). Autophagy Proteins Promote Repair of Endosomal Membranes Damaged by the Salmonella Type Three Secretion System 1. Cell Host & Microbe, 18(5):527-537.
Quast, Isaak; Keller, Christian W; Maurer, Michael A; Giddens, John P; Tackenberg, Björn; Wang, Lai-Xi; Münz, Christian; Nimmerjahn, Falk; Dalakas, Marinos C; Lünemann, Jan D (2015). Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity. Journal of Clinical Investigation, 125(11):4160-4170.
Bransi, Ali; Salgado, Oscar Camilo; Beffinger, Michal; Milo, Karim; Silina, Karina; Yagita, Hideo; Becher, Burkhard; Knuth, Alexander; van den Broek, Maries (2015). Rational combination of immunotherapies with clinical efficacy in mice with advanced cancer. Cancer immunology research, 3(11):1279-1288.
Münz, Christian (2015). The different autophagic roads by which phagosomes travel to lysosomes. The EMBO Journal, 34(19):2391-2392.
Shibutani, Shusaku T; Saitoh, Tatsuya; Nowag, Heike; Münz, Christian; Yoshimori, Tamotsu (2015). Autophagy and autophagy-related proteins in the immune system. Nature Immunology, 16(10):1014-1024.
Croxford, Andrew L; Spath, Sabine; Becher, Burkhard (2015). GM-CSF in Neuroinflammation: Licensing Myeloid Cells for Tissue Damage. Trends in Immunology, 36(10):651-662.
Jung, Jae; Münz, Christian (2015). Immune control of oncogenic γ-herpesviruses. Current Opinion in Virology, 14:79-86.
Johnston, A J; Murphy, K T; Jenkinson, L; Laine, D; Emmrich, K; Faou, P; Weston, R; Jayatilleke, K M; Schloegel, J; Talbo, G; Casey, J L; Levina, V; Wong, W W-L; Dillon, H; Sahay, T; Hoogenraad, J; Anderton, H; Hall, C; Schneider, P; Tanzer, M; Foley, M; Scott, A M; Gregorevic, P; Liu, S Y; Burkly, L C; Lynch, G S; Silke, J; Hoogenraad, N J (2015). Targeting of Fn14 prevents cancer-induced cachexia and prolongs survival. Cell, 162(6):1365-1378.
Hartwig, Tom; Pantelyushin, Stanislav; Croxford, Andrew L; Kulig, Paulina; Becher, Burkhard (2015). Dermal IL-17-producing γδ T cells establish long-lived memory in the skin. European Journal of Immunology, 45(11):3022-3033.
Chijioke, Obinna; Marcenaro, Emanuela; Moretta, Alessandro; Capaul, Riccarda; Münz, Christian (2015). Role of the 2B4 receptor in CD8+ T-cell-dependent immune control of Epstein-barr virus infection in mice with reconstituted human immune system components. Journal of Infectious Diseases, 212(5):803-807.
Waisman, Ari; Liblau, Roland S; Becher, Burkhard (2015). Innate and adaptive immune responses in the CNS. Lancet Neurology, 14(9):945-955.
Onder, Lucas; Nindl, Veronika; Scandella, Elke; Chai, Qian; Cheng, Hung-Wei; Caviezel-Firner, Sonja; Novkovic, Mario; Bomze, David; Maier, Reinhard; Mair, Florian; Ledermann, Birgit; Becher, Burkhard; Waisman, Ari; Ludewig, Burkhard (2015). Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction. European Journal of Immunology, 45(8):2218-2231.
Müller, Andreas Felix; Strauss, Laura; Greter, Melanie; Gast, Heidemarie; Recher, Mike; Becher, Burkhard; Fontana, Adriano (2015). Neutralization of colony-stimulating factor 1 receptor prevents sickness behavior syndrome by reprogramming inflammatory monocytes to produce IL-10. Brain, Behavior, and Immunity, 48:78-85.
Surace, Laura; Guckenberger, Matthias; van den Broek, Maries (2015). Radiation holidays stimulate tumor immunity. OncoTarget, 6(18):15716-15717.
Braun, Simon M G; Pilz, Gregor-Alexander; Machado, Raquel A C; Moss, Jonathan; Becher, Burkhard; Toni, Nicolas; Jessberger, Sebastian (2015). Programming Hippocampal Neural Stem/Progenitor Cells into Oligodendrocytes Enhances Remyelination in the Adult Brain after Injury. Cell Reports, 11(11):1679-1685.
Heppner, Frank L; Ransohoff, Richard M; Becher, Burkhard (2015). Immune attack: the role of inflammation in Alzheimer disease. Nature Reviews Neuroscience, 16(6):358-372.
Hoeffel, Guillaume; Chen, Jinmiao; Lavin, Yonit; Low, Donovan; Almeida, Francisca F; See, Peter; Beaudin, Anna E; Lum, Josephine; Low, Ivy; Forsberg, E Camilla; Poidinger, Michael; Zolezzi, Francesca; Larbi, Anis; Ng, Lai Guan; Chan, Jerry K Y; Greter, Melanie; Becher, Burkhard; Samokhvalov, Igor M; Merad, Miriam; Ginhoux, Florent (2015). C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages. Immunity, 42(4):665-678.
Wei, Lirong; Chahwan, Richard; Wang, Shanzhi; Wang, Xiaohua; Pham, Phuong T; Goodman, Myron F; Bergman, Aviv; Scharff, Matthew D; MacCarthy, Thomas (2015). Overlapping hotspots in CDRs are critical sites for V region diversification. Proceedings of the National Academy of Sciences of the United States of America, 112(7):E728-E737.
Ruf, Melanie; Mittmann, Christiane; Nowicka, Anna M; Hartmann, Arndt; Hermanns, Thomas; Poyet, Cédric; van den Broek, Maries; Sulser, Tullio; Moch, Holger; Schraml, Peter (2015). pVHL/HIF-regulated CD70 expression is associated with infiltration of CD27+ lymphocytes and increased serum levels of soluble CD27 in clear cell renal cell carcinoma. Clinical Cancer Research, 21(4):889-98.
Zhao, Yuxing; Scott, Nicholas A; Fynch, Stacey; Elkerbout, Lorraine; Wong, W Wei-Lynn; Mason, Kylie D; Strasser, Andreas; Huang, David C; Kay, Thomas W H; Thomas, Helen E (2015). Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes. Diabetologia, 58(1):140-148.
Karrer, Maureen; Lopez, Martin Alexander; Meier, Daniel; Mikhail, Cyril; Ogunshola, Omolara O; Müller, Andreas Felix; Strauss, Laura; Tafti, Mehdi; Fontana, Adriano (2015). Cytokine-induced sleep: Neurons respond to TNF with production of chemokines and increased expression of Homer1a in vitro. Brain, Behavior, and Immunity, 47:186-192.
Brosch, Sven; Dietze-Schwonberg, Kirsten; Lopez Kostka, Susanna; Lorenz, Beate; Haak, Stefan; Becher, Burkhard; von Stebut, Esther (2015). Disease Control in cutaneous leishmaniasis is independent of IL-22. Journal of Investigative Dermatology, 135:308-311.
Nowag, Heike; Münz, Christian (2015). Diverting autophagic membranes for exocytosis. Autophagy, 11(2):425-427.
Münz, Christian (2015). EBV Infection of Mice with Reconstituted Human Immune System Components. Current topics in microbiology and immunology, 391:407-423.
Bransi, Ali. Effective immunotherapy of advanced cancer in mice. 2015, University of Zurich, Faculty of Science.
Marroquin Belaunzaran, Osiris; Kleber, Sascha; Schauer, Stefan; Hausmann, Martin; Nicholls, Flora; van den Broek, Maries; Payeli, Sravan; Ciurea, Adrian; Milling, Simon; Stenner, Frank; Shaw, Jackie; Kollnberger, Simon; Bowness, Paul; Petrausch, Ulf; Renner, Christoph (2015). HLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic Rats. PLoS ONE, 10(6):e0130811.
Waisman, Ari; Ginhoux, Florent; Greter, Melanie; Bruttger, Julia (2015). Homeostasis of Microglia in the Adult Brain: Review of Novel Microglia Depletion Systems. Trends in Immunology, 36(10):625-636.
Murugaiyan, Gopal; da Cunha, Andre Pires; Ajay, Amrendra K; Joller, Nicole; Garo, Lucien P; Kumaradevan, Sowmiya; Yosef, Nir; Vaidya, Vishal S; Weiner, Howard L (2015). MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis. Journal of Clinical Investigation, 125(3):1069-1080.
Greter, Melanie; Lelios, Iva; Croxford, Andrew Lewis (2015). Microglia versus myeloid cell nomenclature during brain inflammation. Frontiers in Immunology, 6:249.
Tugues, S; Burkhard, S H; Ohs, I; Vrohlings, M; Nussbaum, K; Vom Berg, J; Kulig, P; Becher, B (2015). New insights into IL-12-mediated tumor suppression. Cell Death and Differentiation, 22(2):237-246.
Münz, Christian (2015). Of LAP, CUPS, and DRibbles - Unconventional Use of Autophagy Proteins for MHC Restricted Antigen Presentation. Frontiers in Immunology, 6:200.
Münz, Christian (2015). Preface. Current topics in microbiology and immunology, 390(Pt 1):v-vi.
Lawlor, K E; et al (2015). RIPK3 promotes cell death NLRP3 inflammasome and interleukin-1 activation in the absence of MLKL. Nature Communications:6:6282.
Surace, Laura. Radiotherapy Supports Tumor Specific Immunity by Acute Inflammation. 2015, University of Zurich, Faculty of Science.
Surace, Laura; Scheifinger, Nicole; van den Broek, Maries (2015). Radiotherapy supports tumor-specific immunity by acute inflammation. OncoImmunology, 6:e1060391.
Martin, Alberto; Chahwan, Richard; Parsa, Jahan Yar; Scharff, Matthew D (2015). Somatic Hypermutation. In: Honjo, T; Reth, M; Radbruch, Andreas; Alt, FW. Molecular Biology of B Cells (Second Edition). USA: Elsevier, 363-388.
Kurtulus, Sema; Sakuishi, Kaori; Ngiow, Shin-Foong; Joller, Nicole; Tan, Dewar J; Teng, Michele W L; Smyth, Mark J; Kuchroo, Vijay K; Anderson, Ana C (2015). TIGIT predominantly regulates the immune response via regulatory T cells. Journal of Clinical Investigation, 125(11):4053-4062.
Quast, Isaak. The IgG paradox: unraveling pro- and anti-inflammatory mechanisms in neuroinflammatory disease. 2015, University of Zurich, Faculty of Science.
Mair, Florian; Joller, Stefanie; Hoeppli, Romy; Onder, Lucas; Hahn, Matthias; Ludewig, Burkhard; Waisman, Ari; Becher, Burkhard (2015). The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells. eLife, 4:e10087.
Nowag, Heike; Guhl, Bruno; Thriene, Kerstin; Romao, Susana; Ziegler, Urs; Dengjel, Jörn; Münz, Christian (2014). Macroautophagy proteins assist Epstein Barr Virus production and get incorporated into the virus particles. EBioMedicine, 1(2-3):116-125.
Münz, Christian (2014). Regulation of innate immunity by the molecular machinery of macroautophagy. Cellular Microbiology, 16(11):1627-1636.
Speiser, Daniel E; Utzschneider, Daniel T; Oberle, Susanne G; Münz, Christian; Romero, Pedro; Zehn, Dietmar (2014). T cell differentiation in chronic infection and cancer: functional adaptation or exhaustion? Nature Reviews. Immunology, 14(11):768-774.
Kübler, Ayline; Woiterski, Jeanette; Witte, Kai-Erik; Bühring, Hans-Jörg; Hartwig, Udo F; Ebinger, Martin; Oevermann, Lena; Mezger, Markus; Herr, Wolfgang; Lang, Peter; Handgretinger, Rupert; Münz, Christian; André, Maya C (2014). Both mature KIR+ and immature KIR- NK cells control pediatric acute B cell precursor leukemia in NOD.Cg-Prkdcscid IL2rgtmWjl/Sz mice. Blood, 124(26):3914-3923.
Azzi, Tarik; Lünemann, Anna; Murer, Anita; Ueda, Seigo; Béziat, Vivien; Malmberg, Karl-Johan; Staubli, Georg; Gysin, Claudine; Berger, Christoph; Münz, Christian; Chijioke, Obinna; Nadal, David (2014). Role for early-differentiated natural killer cells in infectious mononucleosis. Blood, 124(16):2533-2543.
Goto, Yoshiyuki; Obata, Takashi; Kunisawa, Jun; Sato, Shintaro; Ivanov, Ivaylo I; Lamichhane, Aayam; Takeyama, Natsumi; Kamioka, Mariko; Sakamoto, Mitsuo; Matsuki, Takahiro; Setoyama, Hiromi; Imaoka, Akemi; Uematsu, Satoshi; Akira, Shizuo; Domino, Steven E; Kulig, Paulina; Becher, Burkhard; Renauld, Jean-Christophe; Sasakawa, Chihiro; Umesaki, Yoshinori; Benno, Yoshimi; Kiyono, Hiroshi (2014). Innate lymphoid cells regulate intestinal epithelial cell glycosylation. Science, 345(6202):online.
Münz, Christian (2014). Viral infections in mice with reconstituted human immune system components. Immunology Letters, 161(1):118-124.
Antsiferova, Olga; Müller, Anne; Rämer, Patrick C; Chijioke, Obinna; Chatterjee, Bithi; Raykova, Ana; Planas, Raquel; Sospedra, Mireia; Shumilov, Anatoliy; Tsai, Ming-Han; Delecluse, Henri-Jacques; Münz, Christian (2014). Adoptive transfer of EBV specific CD8+ T cell clones can transiently control EBV infection in humanized mice. PLoS Pathogens, 10(8):e1004333.
Chatterjee, Bithi; Leung, Carol Sze; Münz, Christian (2014). Animal models of Epstein Barr virus infection. Journal of Immunological Methods, 410:80-87.
van Oers, J M M; Edwards, Y; Chahwan, R; Zhang, W; Smith, C; Pechuan, X; Schaetzlein, S; Jin, B; Wang, Y; Bergman, A; Scharff, M D; Edelmann, W (2014). The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair. Oncogene, 33(30):3939-3946.
Salguero, Gustavo; Daenthanasanmak, Anusara; Münz, Christian; Raykova, Ana; Guzmán, Carlos A; Riese, Peggy; Figueiredo, Constanca; Länger, Florian; Schneider, Andreas; Macke, Laura; Sundarasetty, Bala Sai; Witte, Torsten; Ganser, Arnold; Stripecke, Renata (2014). Dendritic cell-mediated immune humanization of mice: implications for allogeneic and xenogeneic stem cell transplantation. Journal of Immunology, 192(10):4636-4647.
Wong, W Wei-Lynn; Vince, James E; Lalaoui, Najoua; Lawlor, Kate E; Chau, Diep; Bankovacki, Aleksandra; Anderton, Holly; Metcalf, Donald; O'Reilly, Lorraine; Jost, Philipp J; Murphy, James M; Alexander, Warren S; Strasser, Andreas; Vaux, David L; Silke, John (2014). cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner. Blood, 123(16):2562-2572.
Jandus, Camilla; Boligan, Kayluz Frias; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Démoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E; Baerlocher, Gabriela M; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of Clinical Investigation, 124(4):1810-1820.
Rickinson, Alan B; Long, Heather M; Palendira, Umaimainthan; Münz, Christian; Hislop, Andrew D (2014). Cellular immune controls over Epstein-Barr virus infection: new lessons from the clinic and the laboratory. Trends in Immunology, 35(4):159-169.
Croxford, Andrew L; Karbach, Susanne; Kurschus, Florian C; Wörtge, Simone; Nikolaev, Alexei; Yogev, Nir; Klebow, Sabrina; Schüler, Rebecca; Reissig, Sonja; Piotrowski, Carolin; Brylla, Elke; Bechmann, Ingo; Scheller, Jürgen; Rose-John, Stefan; Wunderlich, F Thomas; Münzel, Thomas; von Stebut, Esther; Waisman, Ari (2014). IL-6 regulates neutrophil microabscess formation in IL-17A-driven psoriasiform lesions. Journal of Investigative Dermatology, 134(3):728-735.
Münz, Christian (2014). Influenza A virus lures autophagic protein LC3 to budding sites. Cell Host & Microbe, 15(2):130-131.
Vahl, J Christoph; Drees, Christoph; Heger, Klaus; Heink, Sylvia; Fischer, Julius C; Nedjic, Jelena; Ohkura, Naganari; Morikawa, Hiromasa; Poeck, Hendrik; Schallenberg, Sonja; Rieß, David; Hein, Marco Y; Buch, Thorsten; Polic, Bojan; Schönle, Anne; Zeiser, Robert; Schmitt-Gräff, Annette; Kretschmer, Karsten; Klein, Ludger; Korn, Thomas; Sakaguchi, Shimon; Schmidt-Supprian, Marc (2014). Continuous T cell receptor signals maintain a functional regulatory t cell pool. Immunity, 41(5):722-736.
Münz, Christian (2014). Dendritic cells during Epstein Barr virus infection. Frontiers in Microbiology:5:308.
Quast, Isaak; Lünemann, Jan D (2014). Fc Glycan-Modulated Immunoglobulin G Effector Functions. Journal of Clinical Immunology, 34(S1):51-55.
Becher, Burkhard; Schlitzer, Andreas; Chen, Jinmiao; Mair, Florian; Sumatoh, Hermi R; Teng, Karen Wei Weng; Low, Donovan; Ruedl, Christiane; Riccardi-Castagnoli, Paola; Poidinger, Michael; Greter, Melanie; Ginhoux, Florent; Newell, Evan W (2014). High-dimensional analysis of the murine myeloid cell system. Nature Immunology, 15(12):1181-1189.
Croxford, Andrew L; Kulig, Paulina; Becher, Burkhard (2014). IL-12-and IL-23 in health and disease. Cytokine & growth factor reviews, 25(4):415-421.
Mair, Florian; Tosevski, Vinko (2014). Intracellular staining for cytokines and transcription factors. Methods in Molecular Biology, 1193:39-49.
Lelios, Iva; Greter, Melanie (2014). Isolation of leukocytes from mouse central nervous system. In: Waisman, Ari; Becher, Burkhard. T-Helper Cells - Methods and Protocols. Springer Protocols: Springer, 15-19.
Romao, Susana; Münz, Christian (2014). LC3-associated phagocytosis. Autophagy, 10(3):ahead of print.
Sledzińska, Anna; Fairbairn, Lynsey; Buch, Thorsten (2014). Manipulation of T cell function and conditional gene targeting in T cells. Methods in Molecular Biology, 1193:153-169.
Bonaccorsi, Irene; Morandi, Barbara; Antsiferova, Olga; Costa, Gregorio; Oliveri, Daniela; Conte, Romana; Pezzino, Gaetana; Vermiglio, Giovanna; Anastasi, Giuseppe Pio; Navarra, Giuseppe; Münz, Christian; Di Carlo, Emma; Mingari, Maria Cristina; Ferlazzo, Guido (2014). Membrane transfer from tumor cells overcomes deficient phagocytic ability of plasmacytoid dendritic cells for the acquisition and presentation of tumor antigens. Journal of Immunology, 192(2):824-32.
Hartmann, Felix J; Khademi, Mohsen; Aram, Jehan; Ammann, Sandra; Kockum, Ingrid; Constantinescu, Cris; Gran, Bruno; Piehl, Fredrik; Olsson, Tomas; Codarri, Laura; Becher, Burkhard (2014). Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells. Nature Communications, 5(5056):online.
Arnò, Benedetta; Grassivaro, Francesca; Rossi, Chiara; Bergamaschi, Andrea; Castiglioni, Valentina; Furlan, Roberto; Greter, Melanie; Favaro, Rebecca; Comi, Giancarlo; Becher, Burkhard; Martino, Gianvito; Muzio, Luca (2014). Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex. Nature Communications, 5(5611):online.
Lohri, Corinne; Hutzli Schaltegger, Claudia S; van den Broek, Maries; Wenger, Roland H; Ruegg, Curzio; Fink, Daniel; Fehr, Mathias K; Knuth, Alexander; Zweifel, Martin (2014). Neutrophil expression of ICAM1, CXCR1, and VEGFR1 in patients with breast cancer before and after adjuvant chemotherapy. Anticancer Research, 34:4693-4700.
Münz, Christian (2014). Role of human natural killer cells during Epstein Barr virus infection. Critical Reviews in Immunology, 34(6):501-507.
Burkhard, Sara H; Mair, Florian; Nussbaum, Kathrin; Hasler, Sabrina; Becher, Burkhard (2014). T cell contamination in flow cytometry gating approaches for analysis of innate lymphoid cells. PLoS ONE, 9(4):e94196.
Becher, Burkhard; Waisman, Ari (2014). T-helper cells: methods and protocols / Preface. In: Becher, Burkhard; Waisman, Ari. T-helper cells: methods and protocols. Methods Mol Biol. UK: Springer, v-vi.
Rickard, James A; Anderton, Holly; Etemadi, Nima; Nachbur, Ueli; Darding, Maurice; Peltzer, Nieves; Lalaoui, Najoua; Lawlor, Kate E; Vanyai, Hannah; Hall, Cathrine; Bankovacki, Aleks; Gangoda, Lahiru; Wong, Wendy Wei-Lynn; Corbin, Jason; Huang, Chunzi; Mocarski, Edward S; Murphy, James M; Alexander, Warren S; Voss, Anne K; Vaux, David L; Kaiser, William J; Walczak, Henning; Silke, John (2014). TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice. eLife, 3:e03464.
Tosevski, Vinko; Mair, Florian (2014). Tracking cells and monitoring proliferation. Methods in Molecular Biology, 1193:51-54.
Vom Berg, Johannes; Vrohlings, Melissa; Haller, Sergio; Haimovici, Aladin; Kulig, Paulina; Sledzinska, Anna; Weller, Michael; Becher, Burkhard (2013). Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection. Journal of Experimental Medicine, 210(13):2803-2811.
Schaetzlein, Sonja; Chahwan, Richard; Avdievich, Elena; Roa, Sergio; Wei, Kaichun; Eoff, Robert L; Sellers, Rani S; Clark, Alan B; Kunkel, Thomas A; Scharff, Matthew D; Edelmann, Winfried (2013). Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes. Proceedings of the National Academy of Sciences of the United States of America, 110(27):E2470-E2479.
Chahwan, Richard; Gravel, Serge; Matsusaka, Takahiro; Jackson, Stephen P (2013). RNF8 links nucleosomal and cytoskeletal ubiquitylation of higher order protein structures. Cell Cycle, 12(8):1161-1162.
Chahwan, Richard; Gravel, Serge; Matsusaka, Takahiro; Jackson, Stephen P (2013). Dma/RNF8 proteins are evolutionarily conserved E3 ubiquitin ligases that target septins. Cell Cycle, 12(6):1000-1008.
Keller, Christian W; Schmitz, Matthias; Münz, Christian; Lünemann, Jan D; Schmidt, Jens (2013). TNF-α upregulates macroautophagic processing of APP/β-amyloid in a human rhabdomyosarcoma cell line. Journal of the Neurological Sciences, 325(1-2):103-107.
Lünemann, Anna; Vanoaica, Liliana D; Azzi, Tarik; Nadal, David; Münz, Christian (2013). A distinct subpopulation of human NK cells restricts B cell transformation by EBV. Journal of Immunology, 191(10):4989-4995.
Gupta, Anurag; Nuber, Natko; Esslinger, Christoph; Wittenbrink, Mareike; Treder, Martin; Landshammer, Alexandro; Noguchi, Takuro; Kelly, Marcus; Gnjatic, Sacha; Ritter, Erika; von Boehmer, Lotta; Nishikawa, Hiroyoshi; Shiku, Hiroshi; Old, Lloyd; Ritter, Gerd; Knuth, Alexander; van den Broek, Maries (2013). A novel human-derived antibody against NY-ESO-1 improves the efficacy of chemotherapy. Cancer Immunity, 13:3.
Walter, Anne; Schäfer, Matthias; Cecconi, Virginia; Matter, Claudia; Urosevic-Maiwald, Mirjana; Belloni, Benedetta; Schönewolf, Nicola; Dummer, Reinhard; Bloch, Wilhelm; Werner, Sabine; Beer, Hans-Dietmar; Knuth, Alexander; van den Broek, Maries (2013). Aldara activates TLR7-independent immune defence. Nature Communications, 4:1560.
Gannage, Monique; Barreira da Silva, Rosa; Münz, Christian (2013). Antigen processing for MHC presentation via macroautophagy. In: van Endert, Peter. Antigen Processing. New York: Springer, 473-488.
Jakka, Gopinadh; Schuberth, Petra C; Thiel, Markus; Held, Gerhard; Stenner, Frank; van den Broek, Maries; Renner, Christoph; Mischo, Axel; Petrausch, Ulf (2013). Antigen-specific in vitro expansion of functional redirected NY-ESO-1-specific human CD8+ T-cells in a cell-free system. Anticancer Research, 33(10):4189-4201.
Caminschi, Irina; Münz, Christian (2013). Autophagy for better or worse during infectious diseases. Frontiers in Immunology:4:205.
Münz, Christian (2013). Autophagy in cellular transformation, survival and communication with the tumor microenvironment. Seminars in Cancer Biology, 23(5):299-300.
Romao, Susana; Gasser, Nathalie; Becker, Andrea C; Guhl, Bruno; Bajagic, Milica; Vanoaica, Danusia; Ziegler, Urs; Roesler, Joachim; Dengjel, Jörn; Reichenbach, Janine; Münz, Christian (2013). Autophagy proteins stabilize pathogen-containing phagosomes for prolonged MHC II antigen processing. Journal of Cell Biology, 203(5):757-66.
Meixlsperger, Sonja; Leung, Carol S; Rämer, Patrick C; Pack, Maggi; Vanoaica, Liliana D; Breton, Gaëlle; Pascolo, Steve; Salazar, Andres M; Dzionek, Andrzej; Schmitz, Jürgen; Steinman, Ralph M; Münz, Christian (2013). CD141+ dendritic cells produce prominent amounts of IFN-α after dsRNA recognition and can be targeted via DEC-205 in humanized mice. Blood, 121(25):5034-5044.
Romao, Susana; Gannage, Monique; Münz, Christian (2013). Checking the garbage bin for problems in the house, or how autophagy assists in antigen presentation to the immune system. Seminars in Cancer Biology, 23(5):391-396.
Codarri, Laura; Greter, Melanie; Becher, Burkhard (2013). Communication between pathogenic T cells and myeloid cells in neuroinflammatory disease. Trends in Immunology, 34(3):114-119.
Jungraithmayr, Wolfgang; Codarri, Laura; Bouchaud, Gregory; Krieg, Carsten; Boyman, Onur; Gyülvészi, Gabor; Becher, Burkhard; Weder, Walter; Münz, Christian (2013). Cytokine complex-expanded natural killer cells improve allogeneic lung transplant function via depletion of donor dendritic cells. American Journal of Respiratory and Critical Care Medicine, 187(12):1349-1359.
Chijioke, Obinna; Münz, Christian (2013). Dendritic cell derived cytokines in human natural killer cell differentiation and activation. Frontiers in Immunology:4:365.
Croxford, Andrew L; Waisman, Ari; Becher, Burkhard (2013). Does dietary salt induce autoimmunity? Cell Research, 23(7):872-873.
Chijioke, Obinna; Müller, Anne; Feederle, Regina; Barros, Mario Henrique M; Krieg, Carsten; Emmel, Vanessa; Marcenaro, Emanuela; Leung, Carol S; Antsiferova, Olga; Landtwing, Vanessa; Bossart, Walter; Moretta, Alessandro; Hassan, Rocio; Boyman, Onur; Niedobitek, Gerald; Delecluse, Henri-Jacques; Capaul, Riccarda; Münz, Christian (2013). Human natural killer cells prevent infectious mononucleosis features by targeting lytic epstein-barr virus infection. Cell Reports, 5(6):1489-1498.
Leung, Carol; Chijioke, Obinna; Gujer, Cornelia; Chatterjee, Bithi; Antsiferova, Olga; Landtwing, Vanessa; McHugh, Donal; Raykova, Ana; Münz, Christian (2013). Infectious diseases in humanized mice. European Journal of Immunology, 43(9):2246-2254.
Recher, M; Malipiero, U; Schaer, D J; Koedel, U; Pfister, H W; Birchler, T; Petrausch, U; Claus, H; Gast, H; Fontana, A (2013). Inhibition of meningitis-associated neutrophil apoptosis by TNF- depends on functional PI3-kinase in monocytes. Journal of Leukocyte Biology, 93(2):259-266.
Chijioke, Obinna; Azzi, Tarik; Nadal, David; Münz, Christian (2013). Innate immune responses against Epstein Barr virus infection. Journal of Leukocyte Biology, 94(6):1185-1190.
Wohn, Christian; Ober-Blöbaum, Julia L; Haak, Stefan; Pantelyushin, Stanislav; Cheong, Cheolho; Zahner, Sonja P; Onderwater, Sabina; Kant, Marius; Weighardt, Heike; Holzmann, Bernhard; Reizis, Boris; Becher, Burkhard; Prens, Errol P; Clausen, Björn E (2013). Langerin(neg) conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice. Proceedings of the National Academy of Sciences of the United States of America, 110(26):10723-10728.
Nuber, Natko; Curioni-Fontecedro, Alessandra; Dannenmann, Stefanie R; Matter, C; von Boehmer, Lotta; Atanackovic, Djordje; Knuth, Alexander; van den Broek, Maries (2013). MAGE-C1/CT7 spontaneously triggers a CD4+ T-cell response in multiple myeloma patients. Leukemia, 27(8):1767-1769.
Münz, Christian (2013). Macroautophagy--friend or foe of viral replication? EMBO Reports, 14(6):483-484.
von Boehmer, Lotta; Mattle, Muriel; Bode, Peter; Landshammer, Alexandro; Schäfer, Carolin; Nuber, Natko; Ritter, Gerd; Old, Lloyd; Moch, Holger; Schäfer, Niklaus; Jäger, Elke; Knuth, Alexander; van den Broek, Maries (2013). NY-ESO-1-specific immunological pressure and escape in a patient with metastatic melanoma. Cancer Immunity, 13:12.
Kreutzfeldt, Mario; Bergthaler, Andreas; Fernandez, Marylise; Brück, Wolfgang; Steinbach, Karin; Vorm, Mariann; Coras, Roland; Blümcke, Ingmar; Bonilla, Weldy V; Fleige, Anne; Forman, Ruth; Müller, Werner; Becher, Burkhard; Misgeld, Thomas; Kerschensteiner, Martin; Pinschewer, Daniel D; Merkler, Doron (2013). Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell-mediated dendrite and synapse loss. Journal of Experimental Medicine, 210(10):2087-2103.
Sharma, Anu; Bode, Beata; Moch, Holger; Okoniewski, Michal; Knuth, Alexander; von Boehmer, Lotta; van den Broek, Maries (2013). Radiotherapy of human sarcoma promotes an intratumoral immune effector signature. Clinical Cancer Research, 19(17):4843-4853.
Greter, Melanie; Merad, Miriam (2013). Regulation of microglia development and homeostasis. Glia, 61(1):121-127.
Leung, Carol S; Maurer, Michael A; Meixlsperger, Sonja; Lippmann, Anne; Cheong, Cheolho; Zuo, Jianmin; Haigh, Tracey; Taylor, Graham; Münz, Christian (2013). Robust T cell stimulation by Epstein-Barr virus-transformed B cells after antigen targeting to DEC-205. Blood, 121(9):1584-1594.
Tsai, Ming-Han; Raykova, Ana; Klinke, Olaf; Bernhardt, Katharina; Gärtner, Kathrin; Leung, Carol S; Geletneky, Karsten; Sertel, Serkan; Münz, Christian; Feederle, Regina; Delecluse, Henri-Jacques (2013). Spontaneous lytic replication and epitheliotropism define an Epstein-Barr virus strain found in carcinomas. Cell Reports, 5(2):458-470.
Dannenmann, Stefanie R; Hermanns, Thomas; Bransi, Ali; Matter, Claudia; von Boehmer, Lotta; Stevanovic, Stefan; Schraml, Peter; Moch, Holger; Knuth, Alexander; van den Broek, Maries (2013). Spontaneous peripheral T-cell responses toward the tumor-associated antigen cyclin D1 in patients with clear cell renal cell carcinoma. Cancer Immunology Research, 1(5):288-295.
Spath, Sabine; Becher, Burkhard (2013). T-bet or not T-bet: Taking the last bow on the autoimmunity stage. European Journal of Immunology, 43(11):2810-2813.
Braumüller, Heidi; Wieder, Thomas; Brenner, Ellen; Aßmann, Sonja; Hahn, Matthias; Alkhaled, Mohammed; Schilbach, Karin; Essmann, Frank; Kneilling, Manfred; Griessinger, Christoph; Ranta, Felicia; Ullrich, Susanne; Mocikat, Ralph; Braungart, Kilian; Mehra, Tarun; Fehrenbacher, Birgit; Berdel, Julia; Niessner, Heike; Meier, Friedegund; van den Broek, Maries; Häring, Hans-Ulrich; Handgretinger, Rupert; Quintanilla-Martinez, Leticia; Fend, Falko; Pesic, Marina; Bauer, Jürgen; Zender, Lars; Schaller, Martin; Schulze-Osthoff, Klaus; Röcken, Martin (2013). T-helper-1-cell cytokines drive cancer into senescence. Nature, 494(7437):361-365.
Sledzińska, Anna; Hemmers, Saskia; Mair, Florian; Gorka, Oliver; Ruland, Jürgen; Fairbairn, Lynsey; Nissler, Anja; Müller, Werner; Waisman, Ari; Becher, Burkhard; Buch, Thorsten (2013). TGF-β signalling is required for CD4⁺ T cell homeostasis but dispensable for regulatory T cell function. PLoS Biology, 11(10):e1001674.
Mair, Florian; Becher, Burkhard (2013). Thy1(+) Sca1(+) innate lymphoid cells infiltrate the CNS during autoimmune inflammation, but do not contribute to disease development. European Journal of Immunology:online.
Hashimoto, Daigo; Chow, Andrew; Noizat, Clara; Teo, Pearline; Beasley, Mary Beth; Leboeuf, Marylene; Becker, Christian D; See, Peter; Price, Jeremy; Lucas, Daniel; Greter, Melanie; Mortha, Arthur; Boyer, Scott W; Forsberg, E Camilla; Tanaka, Masato; van Rooijen, Nico; García-Sastre, Adolfo; Stanley, E Richard; Ginhoux, Florent; Frenette, Paul S; Merad, Miriam (2013). Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity, 38(4):792-804.
Schuberth, Petra C; Hagedorn, Christian; Jensen, Shawn M; Gulati, Pratiksha; van den Broek, Maries; Mischo, Axel; Soltermann, Alex; Jüngel, Astrid; Marroquin Belaunzaran, Osiris; Stahel, Rolf; Renner, Christoph; Petrausch, Ulf (2013). Treatment of malignant pleural mesothelioma by fibroblast activation protein-specific re-directed T cells. Journal of Translational Medicine, 11:187.
Dannenmann, Stefanie Regine; Thielicke, Julia; Stöckli, Martina; Matter, Claudia; von Boehmer, Lotta; Cecconi, Virginia; Hermanns, Thomas; Hefermehl, Lukas; Schraml, Peter; Moch, Holger; Knuth, Alexander; van den Broek, Maries (2013). Tumor-associated macrophages subvert T-cell function and correlate with reduced survival in clear cell renal cell carcinoma. OncoImmunology, 2(3):e23562.
Schliehe, Christopher; Bitzer, Annegret; van den Broek, Maries; Groettrup, Marcus (2012). Stable antigen is most effective for eliciting CD8+ T-cell responses after DNA vaccination and infection with recombinant vaccinia virus in vivo. Journal of Virology, 86(18):9782-9793.
Chahwan, Richard; Edelmann, Winfried; Scharff, Matthew D; Roa, Sergio (2012). AIDing antibody diversity by error-prone mismatch repair. Seminars in Immunology, 24(4):293-300.
Chahwan, Charly; Chahwan, Richard (2012). Aicardi-Goutieres syndrome: from patients to genes and beyond. Clinical Genetics, 81(5):413-420.
Chahwan, Richard; van Oers, Johanna M M; Avdievich, Elena; Zhao, Chunfang; Edelmann, Winfried; Scharff, Matthew D; Roa, Sergio (2012). The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination. Journal of Experimental Medicine, 209(4):671-678.
Becher, Burkhard; Greter, Melanie (2012). Acquitting an APC: DCs found "not guilty" after trial by ablation. European Journal of Immunology, 42(10):2551-2554.
Münz, Christian (2012). Antigen Processing for MHC Class II Presentation via Autophagy. Frontiers in Immunology:3:9.
Randow, Felix; Münz, Christian (2012). Autophagy in the regulation of pathogen replication and adaptive immunity. Trends in Immunology, 33(10):475-87.
White, Robert E; Rämer, Patrick C; Naresh, Kikkeri N; Meixlsperger, Sonja; Pinaud, Laurie; Rooney, Cliona; Savoldo, Barbara; Coutinho, Rita; Bödör, Csaba; Gribben, John; Ibrahim, Hazem A; Bower, Mark; Nourse, Jamie P; Gandhi, Maher K; Middeldorp, Jaap; Cader, Fathima Z; Murray, Paul; Münz, Christian; Allday, Martin J (2012). EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors. Journal of Clinical Investigation, 122(4):1487-1502.
Comabella, M; Kakalacheva, K; Río, J; Münz, C; Montalban, X; Lünemann, J D (2012). EBV-specific immune responses in patients with multiple sclerosis responding to IFNβ therapy. Multiple Sclerosis, 18(5):605-609.
Greter, Melanie; Helft, Julie; Chow, Andrew; Hashimoto, Daigo; Mortha, Arthur; Agudo-Cantero, Judith; Bogunovic, Milena; Gautier, Emmanuel L; Miller, Jennifer; Leboeuf, Marylene; Lu, Geming; Aloman, Costica; Brown, Brian D; Pollard, Jeffrey W; Xiong, Huabao; Randolph, Gwendalyn J; Chipuk, Jerry E; Frenette, Paul S; Merad, Miriam (2012). GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells. Immunity, 36(6):1031-1046.
Klionsky, Daniel J; Münz, Christian; Scharl, Michael; Bornhauser, Beat C; Bourquin, Jean-Pierre; Buzgariu, Wanda; Clarke, Peter G H (2012). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 8(4):445-544.
Becher, Burkhard; Pantelyushin, Stanislav (2012). Hiding under the skin: Interleukin-17-producing γδ T cells go under the skin? Nature Medicine, 18(12):1748-1750.
Romano, Emanuela; Cotari, Jesse W; Barreira da Silva, Rosa; Betts, Brian C; Chung, David J; Avogadri, Francesca; Fink, Mitsu J; St Angelo, Erin T; Mehrara, Babak; Heller, Glenn; Münz, Christian; Altan-Bonnet, Gregoire; Young, James W (2012). Human Langerhans cells use an IL-15R-α/IL-15/pSTAT5-dependent mechanism to break T-cell tolerance against the self-differentiation tumor antigen WT1. Blood, 119(22):5182-5190.
Moulin, M; Anderton, H; Voss, A K; Thomas, T; Wong, W W L; Bankovacki, A; Feltham, R; Chau, D; Cook, W D; Silke, J; Vaux, D L (2012). IAPs must limit activation of RIP kinases by TNF Receptor 1 to prevent embryonic lethality. The EMBO Journal, 31(7):1679-1691.
Coccia, Margherita; Harrison, Oliver J; Schiering, Chris; Asquith, Mark J; Becher, Burkhard; Powrie, Fiona; Maloy, Kevin J (2012). IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells. Journal of Experimental Medicine, 209(9):1595-1609.
Croxford, Andrew L; Mair, Florian; Becher, Burkhard (2012). IL-23: one cytokine in control of autoimmunity. European Journal of Immunology, 42(9):2263-2273.
Vom Berg, Johannes; Prokop, Stefan; Miller, Kelly R; Obst, Juliane; Kälin, Roland E; Lopategui-Cabezas, Ileana; Wegner, Anja; Mair, Florian; Schipke, Carola G; Peters, Oliver; Winter, York; Becher, Burkhard; Heppner, Frank L (2012). Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline. Nature Medicine, 18(12):1812-1819.
Vince, J E; Wong, W Wei-Lynn; Gentle, I E; Lawlor, K E; Allam, R; O'Reilly, L; Mason, K; Gross, O; Ma, S; Guarda, G; Anderton, H; Castillo, R; Häcker, G; Silke, J; Tschopp, J (2012). Inhibitor of apoptosis (IAP) proteins limit RIP3 dependent IL-1 activation. Immunity, 36(2):215-227.
Vom Berg, Johannes. Interleukin-12 in Combination with CTLA-4 Blockade Leads to T-cell Dependent Rejection of Advanced Stage Glioma. 2012, University of Zurich, Faculty of Medicine.
Jelcic, I; Hsu, K C; Kakalacheva, K; Breiden, P; Dupont, B; Uhrberg, M; Martin, R; Münz, C; Lünemann, J D (2012). Killer immunoglobulin-like receptor locus polymorphisms in multiple sclerosis. Multiple Sclerosis, 18(7):951-958.
Tracy, Sean I; Kakalacheva, Kristina; Lünemann, Jan D; Luzuriaga, Katherine; Middeldorp, Jaap; Thorley-Lawson, David A (2012). Persistence of Epstein-Barr virus in self-reactive memory B cells. Journal of Virology, 86(22):12330-12340.
Locatelli, Giuseppe; Wörtge, Simone; Buch, Thorsten; Ingold, Barbara; Frommer, Friederike; Sobottka-Brillout, Bettina; Krüger, Martin; Karram, Khalad; Bühlmann, Claudia; Bechmann, Ingo; Heppner, Frank L; Waisman, Ari; Becher, Burkhard (2012). Primary oligodendrocyte death does not elicit anti-CNS immunity. Nature Neuroscience, 15(4):543-550.
Maurer, Michael A; Rakocevic, Goran; Leung, Carol S; Quast, Isaak; Lukačišin, Martin; Goebels, Norbert; Münz, Christian; Wardemann, Hedda; Dalakas, Marinos; Lünemann, Jan D (2012). Rituximab induces sustained reduction of pathogenic B cells in patients with peripheral nervous system autoimmunity. Journal of Clinical Investigation, 122(4):1393-1402.
Pantelyushin, Stanislav; Haak, Stefan; Ingold, Barbara; Kulig, Paulina; Heppner, Frank L; Navarini, Alexander A; Becher, Burkhard (2012). Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice. Journal of Clinical Investigation, 122(6):2252-2256.
Greter, Melanie; Lelios, Iva; Pelczar, Pawel; Hoeffel, Guillaume; Price, Jeremy; Leboeuf, Marylene; Kündig, Thomas M; Frei, Karl; Ginhoux, Florent; Merad, Miriam; Becher, Burkhard (2012). Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia. Immunity, 37(6):1050-1060.
Ascherio, Alberto; Munger, Kassandra L; Lünemann, Jan D (2012). The initiation and prevention of multiple sclerosis. Nature Reviews. Neurology, 8(11):602-612.
Locatelli, Giuseppe. The role of oligodendrocytes in demyelinating pathologies of the CNS. 2012, University of Zurich, Faculty of Medicine.
Damgaard, R B; Nachbur, U; Yabal, M; Wong, W W-L; Fiil, B K; Kastirr, M; Rieser, E; Rickard, J A; Bankovacki, A; Peschel, C; Ruland, J; Bekker-Jensen, S; Mailand, N; Kaufmann, T; Strasser, A; Walczak, H; Silke, J; Jost, P J; Gyrd-Hansen, M (2012). The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity. Molecular Cell, 46(6):746-758.
Recher, M; Sahrbacher, U; Bremer, J; Arndt, B; Steiner, U; Fontana, A (2012). Treatment of inclusion body myositis: is low-dose intravenous immunoglobulin the solution? Rheumatology International, 32(2):469-472.
Pantelyushin, Stanislav. γδ T Cells and Innate Lymphocytes Initiate Psoriasis-like Inflammation in Mice. 2012, University of Zurich, Faculty of Medicine.
Barreira da Silva, Rosa; Graf, C; Münz, C (2011). Cytoskeletal stabilization of inhibitory interactions in immunologic synapses of mature human dendritic cells with natural killer cells. Blood, 118(25):6487-6498.
Chahwan, Richard; Edelmann, Winfried; Scharff, Matthew D; Roa, Sergio (2011). Mismatch-mediated error prone repair at the immunoglobulin genes. Biomedicine & Pharmacotherapy, 65(8):529-536.
Barreira da Silva, R; Münz, C (2011). Natural killer cell activation by dendritic cells: balancing inhibitory and activating signals. Cellular and Molecular Life Sciences, 68(21):3505-3518.
Münz, C (2011). Beclin-1 targeting for viral immune escape. Viruses, 3(7):1166-1178.
Romao, S; Münz, C (2011). Autophagy of pathogens alarms the immune system and participates in its effector functions. Swiss Medical Weekly, 141:w13198.
Chijioke, Obinna; Münz, Christian (2011). Interactions of human myeloid cells with natural killer cell subsets in vitro and in vivo. Journal of Biomedicine and Biotechnology, 2011:251679.
Chahwan, Richard; Wontakal, Sandeep N; Roa, Sergio (2011). The multidimensional nature of epigenetic information and its role in disease. Discovery Medicine, 11(58):233-43.
Keller, C W; Fokken, C; Turville, S G; Lünemann, A; Schmidt, J; Münz, C; Lünemann, J D (2011). TNF-{alpha} induces macroautophagy and regulates MHC class II expression in human skeletal muscle cells. Journal of Biological Chemistry, 286(5):3970-3980.
Tsang, M L; Münz, C (2011). Cytolytic T lymphocytes from HLA-B8+ donors frequently recognize the Hodgkin's lymphoma associated latent membrane protein 2 of Epstein Barr virus. Herpesviridae, 2:4.
Rämer, P C; Chijioke, O; Meixlsperger, S; Leung, C S; Münz, C (2011). Mice with human immune system components as in vivo models for infections with human pathogens. Immunology and Cell Biology, 89(3):408-416.
Taylor, G S; Mautner, J; Münz, C (2011). Autophagy in herpesvirus immune control and immune escape. Herpesviridae, 2:2.
Rostock, M; Fischer, J; Mumm, A; Stammwitz, U; Saller, R; Bartsch, H H (2011). Black cohosh (Cimicifuga racemosa) in tamoxifen-treated breast cancer patients with climacteric complaints - a prospective observational study. Gynecological Endocrinology, 27(10):844-848.
Prodinger, C; Bunse, J; Krüger, M; Schiefenhövel, F; Brandt, C; Laman, J D; Greter, M; Immig, K; Heppner, F; Becher, B; Bechmann, I (2011). CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system. Acta Neuropathologica, 121(4):445-458.
Sobottka-Brillout, Bettina; Ziegler, Urs; Kaech, Andres; Becher, B; Goebels, Norbert (2011). CNS live imaging reveals a new mechanism of myelination: The liquid croissant model. Glia, 59(12):1841-1849.
Hitzler, I; Oertli, M; Becher, B; Agger, E M; Müller, Anne (2011). Dendritic cells prevent rather than promote immunity conferred by a helicobacter vaccine using a mycobacterial adjuvant. Gastroenterology, 141(1):186-196.e1.
Winnik, S; Lohmann, C; Richter, E K; Schäfer, N; Song, W L; Leiber, F; Mocharla, P; Hofmann, J; Klingenberg, R; Borén, J; Becher, B; Fitzgerald, G A; Lüscher, T F; Matter, C M; Beer, J H (2011). Dietary {alpha}-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation. European Heart Journal, 32(20):2573-2584.
Arnold, I C; Dehzad, N; Reuter, S; Martin, H; Becher, B; Taube, C; Müller, Anne (2011). Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells. Journal of Clinical Investigation, 121(8):3088-3093.
Taube, C; Tertilt, C; Gyülveszi, G; Dehzad, N; Kreymborg, K; Schneeweiss, K; Michel, E; Reuter, S; Renauld, J C; Arnold-Schild, D; Schild, H; Buhl, R; Becher, B (2011). IL-22 is produced by innate lymphoid cells and limits inflammation in allergic airway disease. PLoS ONE, 6(7):e21799.
Lünemann, A; Tackenberg, B; DeAngelis, T; da Silva, R B; Messmer, B; Vanoaica, L D; Miller, A; Apatoff, B; Lublin, F D; Lünemann, J D; Münz, C (2011). Impaired IFN-γ production and proliferation of NK cells in multiple sclerosis. International Immunology, 23(2):139-148.
Gentle, I E; Wong, W W L; Evans, J M; Bankovacki, A; Cook, W D; Khan, N R; Nachbur, U; Rickard, J; Anderton, H; Moulin, M; Lluis, J M; Moujalled, D M; Silke, J; Vaux, D L (2011). In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8. Journal of Biological Chemistry, 286(15):13282-13291.
Kakalacheva, K; Maurer, M A; Tackenberg, B; Münz, C; Willcox, N; Lünemann, J D (2011). Intrathymic Epstein-Barr virus infection is not a prominent feature of myasthenia gravis. Annals of Neurology, 70(3):508-514.
Gerlach, B; Cordier, S M; Schmukle, A C; Emmerich, C H; Rieser, E; Haas, T L; Webb, A I; Rickard, J A; Anderton, H; Wong, W W L; Nachbur, U; Gangoda, L; Warnken, U; Purcell, A W; Silke, J; Walczak, H (2011). Linear ubiquitination prevents inflammation and regulates immune signalling. Nature, 471(7340):591-598.
Münz, C (2011). Macroautophagy during innate immune activation. Frontiers in Microbiology, 2:72.
Hofmann, J; Mair, F; Greter, M; Schmidt-Supprian, M; Becher, B (2011). NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses. Journal of Experimental Medicine, 208(9):1917-1929.
Wolf, M J. Novel insights into the functions of CCR2 in tumor cell metastasis and lymphotoxin in liver cancer development. 2011, University of Zurich, Faculty of Science.
Codarri, L; Gyülvészi, G; Tosevski, V; Hesske, L; Fontana, A; Magnenat, L; Suter, T; Becher, B (2011). RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nature Immunology, 12(6):560-567.
Stein, Matthias Alexander Sokrates. SIRT1 diminishes atherogenesis by suppressing NF-kB signaling-mediated pro-inflammatory events. 2011, University of Zurich, Faculty of Science.
Becher, B; Segal, B M (2011). T(H)17 cytokines in autoimmune neuro-inflammation. Current Opinion in Immunology, 23(6):707-712.
Taraborrelli, C; Palchykova, S; Tobler, I; Gast, H; Birchler, T; Fontana, A (2011). TNFR1 is essential for CD40, but not for lipopolysaccharide-induced sickness behavior and clock gene dysregulation. Brain, Behavior, and Immunity, 25(3):434-442.
Kakalacheva, K; Münz, C; Lünemann, J D (2011). Viral triggers of multiple sclerosis. Biochimica et Biophysica Acta, 1812(2):132-140.
Chahwan, Richard; Wontakal, Sandeep N; Roa, Sergio (2010). Crosstalk between genetic and epigenetic information through cytosine deamination. Trends in Genetics : Tig, 26(10):443-448.
Irla, M; Küpfer, N; Suter, T; Lissilaa, R; Benkhoucha, M; Skupsky, J; Lalive, P H; Fontana, A; Reith, W; Hugues, S (2010). MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity. Journal of Experimental Medicine, 207(9):1891-1905.
Johansson, T; Broll, I; Frenz, T; Hemmers, S; Becher, B; Zeilhofer, Hanns Ulrich; Buch, T (2010). Building a zoo of mice for genetic analyses: A comprehensive protocol for the rapid generation of BAC transgenic mice. Genesis: The Journal of Genetics and Development, 48(4):264-280.
Huppert, J; Closhen, D; Croxford, A; White, R; Kulig, P; Pietrowski, E; Bechmann, I; Becher, B; Luhmann, H J; Waisman, A; Kuhlmann, C R W (2010). Cellular mechanisms of IL-17-induced blood-brain barrier disruption. FASEB Journal, 24(4):1023-1034.
Ramachandran, Shaliny; Chahwan, Richard; Nepal, Rajeev M; Frieder, Darina; Panier, Stephanie; Roa, Sergio; Zaheen, Ahmad; Durocher, Daniel; Scharff, Matthew D; Martin, Alberto (2010). The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination. Proceedings of the National Academy of Sciences of the United States of America, 107(2):809-814.
Münz, C (2010). Antigen processing for MHC presentation by autophagy. F1000 Biology Reports, (2):61.
Münz, C (2010). Antigen processing via autophagy--not only for MHC class II presentation anymore? Current Opinion in Immunology, 22(1):89-93.
Comabella, M; Montalban, X; Horga, A; Messmer, B; Kakalacheva, K; Strowig, T; Caballero, E; Münz, C; Lünemann, J D (2010). Antiviral immune response in patients with multiple sclerosis and healthy siblings. Multiple Sclerosis, 16(3):355-358.
Klein, L; Münz, C; Lünemann, J D (2010). Autophagy-mediated antigen processing in CD4(+) T cell tolerance and immunity. FEBS Letters, 584(7):1405-1410.
Hofmann, J; Greter, M; Du Pasquier, L; Becher, B (2010). B-cells need a proper house, whereas T-cells are happy in a cave: the dependence of lymphocytes on secondary lymphoid tissues during evolution. Trends in Immunology, 31(4):144-153.
Wong, W W; Boutros, P C; Wasylishen, A R; Guckert, K D; O'Brien, E M; Griffiths, R; Martirosyan, A R; Bros, C; Jurisica, I; Langler, R F; Penn, L Z (2010). Characterization of the apoptotic response of human leukemia cells to organosulfur compounds. BMC Cancer, 10:351.
Codarri, L; Fontana, A; Becher, B (2010). Cytokine networks in multiple sclerosis: lost in translation. Current Opinion in Neurology, 23(3):205-211.
Lünemann, J D; Tackenberg, B; Stein, A; Wandinger, K P; Oertel, W H; Wagner, H J; Münz, C; Meisel, H; Sommer, N; Zipp, F (2010). Dysregulated Epstein-Barr virus infection in patients with CIDP. Journal of Neuroimmunology, 218(1-2):107-111.
Lünemann, J D; Tintoré, M; Messmer, B; Strowig, T; Rovira, A; Perkal, H; Caballero, E; Münz, C; Montalban, X; Comabella, M (2010). Elevated Epstein-Barr virus-encoded nuclear antigen-1 immune responses predict conversion to multiple sclerosis. Annals of Neurology, 67(2):159-169.
Moransard, M; Sawitzky, M; Fontana, A; Suter, T (2010). Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis. Glia, 58(5):559-571.
Rozenberg, I; Sluka, S H M; Rohrer, L; Hofmann, J; Becher, B; Akhmedov, A; Soliz, J; Mocharla, P; Borén, J; Johansen, P; Steffel, J; Watanabe, T; Lüscher, T F; Tanner, F C (2010). Histamine H1 receptor promotes atherosclerotic lesion formation by increasing vascular permeability for low-density lipoproteins. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(5):923-930.
Strowig, T; Chijioke, O; Carrega, P; Arrey, F; Meixlsperger, S; Rämer, P C; Ferlazzo, G; Münz, C (2010). Human NK cells of mice with reconstituted human immune system components require preactivation to acquire functional competence. Blood, 116(20):4158-4167.
Eisenring, M; vom Berg, J; Kristiansen, G; Saller, E; Becher, B (2010). IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46. Nature Immunology, 11(11):1030-1038.
Hesske, L; Vincenzetti, C; Heikenwalder, M; Prinz, M; Reith, W; Fontana, A; Suter, T (2010). Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation. Brain: A Journal of Neurology, 133(6):1637-1654.
Pinschewer, D D; Flatz, L; Steinborn, R; Horvath, E; Fernandez, M; Lutz, H; Suter, M; Bergthaler, A (2010). Innate and adaptive immune control of genetically engineered live-attenuated arenavirus vaccine prototypes. International Immunology, 22(9):749-756.
Gannage, M; Münz, C (2010). MHC presentation via autophagy and how viruses escape from it. Seminars in Immunopathology, 32(4):373-381.
Fontana, A; Gast, H; Reith, W; Recher, M; Birchler, T; Bassetti, C L (2010). Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss? Brain: A Journal of Neurology, 133(5):1300-1311.
Wong, W Wei-Lynn; Gentle, I G; Nachbur, U; Carter, H; Vaux, D L; Silke, J (2010). RIPK1 is not essential for TNFR1-induced activation of NF-κB. Cell Death and Differentiation, 17:482-487.
Stein, S; Lohmann, C; Schäfer, N; Hofmann, J; Rohrer, L; Besler, C; Rothgiesser, K M; Becher, B; Hottiger, M O; Borén, J; McBurney, M W; Landmesser, U; Lüscher, T F; Matter, C M (2010). SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis. European Heart Journal, 31(18):2301-2309.
Münz, C (2010). Selective macroautophagy for immunity. Immunity, 32(3):298-299.
Lluis, J M; Nachbur, U; Cook, W D; Gentle, I E; Moujalled, D; Moulin, M; Wong, W W L; Khan, N; Chau, D; Callus, B A; Vince, J E; Silke, J; Vaux, D L (2010). TAK1 is required for survival of mouse fibroblasts treated with TRAIL, and does so by NF-kappaB dependent induction of cFLIPL. PLoS ONE, 5(1):e8620.
Gannagé, M; Rämer, P C; Münz, C (2010). Targeting Beclin 1 for viral subversion of macroautophagy. Autophagy, 6(1):166-167.
Comabella, M; Montalban, X; Münz, C; Lünemann, J D (2010). Targeting dendritic cells to treat multiple sclerosis. Nature Reviews. Neurology, 6(9):499-507.
Kräutler, N. The origin of follicular dendritic cells. 2010, University of Zurich, Faculty of Science.
Elzi, L; Marzolini, C; Furrer, H; Ledergerber, B; Cavassini, M; Hirschel, B; Vernazza, P; Bernasconi, E; Weber, R; Battegay, M (2010). Treatment modification in human immunodeficiency virus-infected individuals starting combination antiretroviral therapy between 2005 and 2008. Archives of Internal Medicine, 170(1):57-65.
Feltham, Rebecca L; Moulin, Maryline; Vince, James E; Mace, Peter D; Wong, W Wei-Lynn; Anderton, Holly; Day, Catherine L; Vaux, David L; Silke, John (2010). Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding. Journal of Biological Chemistry, 285(23):17525-17536.
Haybaeck, J. Mechanisms of inflammation-induced hepatocarcinogenesis and prion transmission via the aerial route. 2009, University of Zurich, Faculty of Science.
Schreiner, B; Heppner, F L; Becher, B (2009). Modeling multiple sclerosis in laboratory animals. Seminars in Immunopathology, 31(4):479-495.
Stendel, R; Cetina Biefer, H R; Dékány, G M; Kubota, H; Münz, C; Wang, S; Mohler, H; Yonekawa, Y; Frei, K (2009). The antibacterial substance taurolidine exhibits anti-neoplastic action based on a mixed type of programmed cell death. Autophagy, 5(2):194-210.
Martins, José Barros Oliveira. Alpha-cleavage of the prion protein and the putative function of the prion protein in lymphocyte homeostasis. 2009, University of Zurich, Faculty of Science.
Wong, W Wei-Lynn; Silke, John (2009). Another facet of ubiquitylation: death. Journal of Molecular Cell Biology, 1(2):80-81.
Münz, C; Lünemann, J D; Getts, M T; Miller, S D (2009). Antiviral immune responses: triggers of or triggered by autoimmunity? Nature Reviews. Immunology, 9(4):246-258.
Gannagé, M; Münz, C (2009). Autophagy in MHC class II presentation of endogenous antigens. In: Levine, B; Yoshimori, T; Deretic, V. Autophagy in Infection and Immunity. Germany: Springer, 123-140.
Ahmed, Afsar U; Moulin, Maryline; Coumailleau, Franck; Wong, W Wei-Lynn; Miasari, Maria; Carter, Holly; Silke, John; Cohen- Tannoudji, Michel; Vince, James E; Vaux, David L (2009). CARP2 deficiency does not alter induction of NFkappaB by TNFα. Current Biology, 19(1):R15-R17.
Geserick, P; Hupe, M; Moulin, M; Wong, W Wei-Lynn; Feoktistova, M; Kellert, B; Gollnick, H; Silke, J; Leverkus, M (2009). Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment. Journal of Cell Biology, 187(7):1037-1054.
Moormann, A M; Heller, K N; Chelimo, K; Embury, P; Ploutz-Snyder, R; Otieno, J A; Oduor, M; Münz, C; Rochford, R (2009). Children with endemic Burkitt lymphoma are deficient in EBNA1-specific IFN-gamma T cell responses. International Journal of Cancer, 124(7):1721-1726.
Sobottka-Brillout, Bettina; Harrer, M D; Ziegler, U; Fischer, K; Wiendl, H; Hünig, T; Becher, B; Goebels, N (2009). Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss. American Journal of Pathology, 175(3):1160-1166.
Durieux, P F; Bearzatto, B; Guiducci, S; Buch, T; Waisman, A; Zoli, M; Schiffmann, S N; de Kerchove d'Exaerde, A (2009). D2R striatopallidal neurons inhibit both locomotor and drug reward processes. Nature Neuroscience, 12(4):393-395.
Ferlazzo, G; Münz, C (2009). Dendritic cell interactions with NK cells from different tissues. Journal of Clinical Immunology, 29(3):265-273.
Lünemann, J D; Münz, C (2009). EBV in MS: guilty by association? Trends in Immunology, 30(6):243-248.
Münz, C (2009). Enhancing immunity through autophagy. Annual Review of Immunology, 27:423-449.
Haak, S; Croxford, A L; Kreymborg, K; Heppner, F L; Pouly, S; Becher, B; Waisman, A (2009). IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice. Journal of Clinical Investigation, 119(1):61-69.
Gyülvészi, Gabor; Haak, Stefan; Becher, Burkhard (2009). IL-23-driven encephalo-tropism and Th17 polarization during CNS-inflammation in vivo. European Journal of Immunology, 39(7):1864-1869.
Nowak, E C; Weaver, C T; Turner, H; Begum-Haque, S; Becher, B; Schreiner, B; Coyle, A J; Kasper, L H; Noelle, R J (2009). IL-9 as a mediator of Th17-driven inflammatory disease. Journal of Experimental Medicine, 206(8):1653-1660.
Düber, S; Hafner, M; Krey, M; Lienenklaus, S; Roy, B; Hobeika, E; Reth, M; Buch, T; Waisman, A; Kretschmer, K; Weiss, S (2009). Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells. Blood, 114(24):4960-4967.
Gannagé, M; Münz, C (2009). Macroautophagy in immunity and tolerance. Traffic, 10(6):615-60.
Gannagé, M; Dormann, D; Albrecht, R; Dengjel, J; Torossi, T; Rämer, P C; Lee, M; Strowig, T; Arrey, F; Conenello, G; Pypaert, M; Andersen, J; García-Sastre, A; Münz, C (2009). Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes. Cell Host & Microbe, 6(4):367-380.
Gannagé, M; Münz, C (2009). Monitoring macroautophagy by major histocompatibility complex class II presentation of targeted antigens. Methods in Enzymology, 452:403-421.
Meixlsperger, S; Münz, C (2009). Morbus Crohn--a disease of failing macroautophagy in the immune system? International Immunology, 21(11):1205-1211.
Greter, M; Hofmann, J; Becher, B (2009). Neo-lymphoid aggregates in the adult liver can initiate potent cell-mediated immunity. PLoS Biology, 7(5):e1000109.
Strowig, T; Gurer, C; Ploss, A; Liu, Y F; Arrey, F; Sashihara, J; Koo, G; Rice, C M; Young, J W; Chadburn, A; Cohen, J I; Münz, C (2009). Priming of protective T cell responses against virus-induced tumors in mice with human immune system components. Journal of Experimental Medicine, 206(6):1423-1434.
Leppkes, M; Becker, C; Ivanov, I I; Hirth, S; Wirtz, S; Neufert, C; Pouly, S; Murphy, A J; Valenzuela, D M; Yancopoulos, G D; Becher, B; Littman, D R; Neurath, M F (2009). RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F. Gastroenterology, 136(1):257-267.
Lünemann, A; Lünemann, J D; Münz, C (2009). Regulatory NK-cell functions in inflammation and autoimmunity. Molecular Medicine, 15(9-10):352-358.
Han, J H; Kushner, S A; Yiu, A P; Hsiang, H L; Buchanan, T; Waisman, A; Bontempi, B; Neve, R L; Frankland, P W; Josselyn, S A (2009). Selective erasure of a fear memory. Science, 323(5920):1492-1496.
Vince, J E; Pantaki, D; Feltham, R; Mace, P D; Cordier, S M; Schmukle, A C; Davidson, A J; Callus, B A; Wong, W Wei-Lynn; Gentle, I E; Carter, H; Lee, E F; Walczak, H; Day, C L; Vaux, D L; Silke, J (2009). TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis. Journal of Biological Chemistry, 284(51):35906-35915.
Haak, S; Gyülvészi, G; Becher, B (2009). Th17 cells in autoimmune disease: changing the verdict. Immunotherapy, 1(2):199-203.
Lünemann, J D; Jelcic, I; Roberts, S; Lutterotti, A; Tackenberg, B; Martin, R; Münz, C (2008). EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-gamma and IL-2. Journal of Experimental Medicine, 205(8):1763-1773.
Cayrol, Romain; Wosik, Karolina; Berard, Jennifer L; Dodelet-Devillers, Aurore; Ifergan, Igal; Kebir, Hania; Haqqani, Arsalan S; Kreymborg, Katharina; Krug, Sebastian; Moumdjian, Robert; Bouthillier, Alain; Becher, Burkhard; Arbour, Nathalie; David, Samuel; Stanimirovic, Danica; Prat, Alexandre (2008). Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system. Nature Immunology, 9(2):137-45.
Lang, P A; Contaldo, C; Georgiev, P; El-Badry, A M; Recher, M; Kurrer, M; Cervantes-Barragan, L; Ludewig, B; Calzascia, T; Bolinger, B; Merkler, D; Odermatt, B; Bader, M; Graf, R; Clavien, P A; Hegazy, A N; Löhning, M; Harris, N L; Ohashi, P S; Hengartner, H; Zinkernagel, R M; Lang, K S (2008). Aggravation of viral hepatitis by platelet-derived serotonin. Nature Medicine, 14(7):756-761.
Wong, W W L; Puthalakath, H (2008). Bcl-2 family proteins: The sentinels of the mitochondrial apoptosis pathway. IUBMB Life, 60(6):390-397.
Lünemann, J D; Huppke, P; Roberts, S; Brück, W; Gärtner, J; Münz, C (2008). Broadened and elevated humoral immune response to EBNA1 in pediatric multiple sclerosis. Neurology, 71(13):1033-1035.
Harzheim, Dagmar; Pfeiffer, K Holger; Fabritz, Larissa; Kremmer, Elisabeth; Buch, Thorsten; Waisman, Ari; Kirchhof, Paulus; Kaupp, U Benjamin; Seifert, Reinhard (2008). Cardiac pacemaker function of HCN4 channels in mice is confined to embryonic development and requires cyclic AMP. The EMBO Journal, 27(4):692-703.
Becher, B (2008). Central nervous system immune surveillance: on natalizumab, dendritic cells, and dangerous immune privilege. Archives of Neurology, 65(12):1566-1567.
Lind, Evan F; Ahonen, Cory L; Wasiuk, Anna; Kosaka, Yoko; Becher, Burkhard; Bennett, Kathy A; Noelle, Randolph J (2008). Dendritic cells require the NF-kappaB2 pathway for cross-presentation of soluble antigens. Journal of Immunology, 181(1):354-363.
Prinz, Marco; Schmidt, Hauke; Mildner, Alexander; Knobeloch, Klaus-Peter; Hanisch, Uwe-Karsten; Raasch, Jenni; Merkler, Doron; Detje, Claudia; Gutcher, Ilona; Mages, Jörg; Lang, Roland; Martin, Roland; Gold, Ralf; Becher, Burkhard; Brück, Wolfgang; Kalinke, Ulrich (2008). Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity, 28(5):675-686.
Lüth, S; Huber, S; Schramm, C; Buch, T; Zander, S; Stadelmann, C; Brück, W; Wraith, D C; Herkel, J; Lohse, A W (2008). Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs. Journal of Clinical Investigation, 118(10):3403-10.
Hutter, G. Establishing a Humanized Mouse Model to Study Prions. 2008, University of Zurich, Faculty of Science.
Münz, C; Becher, B (2008). Experimental immunology in Zürich: the legacy of studying disease-related Ag. European Journal of Immunology, 38(11):2924-2926.
Lünemann, A; Lünemann, J D; Roberts, S; Messmer, B; Barreira da Silva, R; Raine, C S; Münz, C (2008). Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition. Journal of Immunology, 181(9):6170-6177.
Münz, C; Moormann, A (2008). Immune escape by Epstein-Barr virus associated malignancies. Seminars in Cancer Biology, 18(6):381-387.
Croxford, Andrew L; Akilli-Ozturk, Ozlem; Rieux-Laucat, Frederic; Förster, Irmgard; Waisman, Ari; Buch, Thorsten (2008). MHC-restricted T cell receptor signaling is required for alpha beta TCR replacement of the pre T cell receptor. European Journal of Immunology, 38(2):391-399.
Münz, C (2008). Non-cytotoxic protection by human NK cells in mucosal secondary lymphoid tissues. European Journal of Immunology, 38(11):2946-2948.
Harrer, M D. Organotypic CNS Slice Cultures as an in vitro Model for Damage and Repair in Multiple Sclerosis. 2008, University of Zurich, Faculty of Science.
Heller, K N; Arrey, F; Steinherz, P; Portlock, C; Chadburn, A; Kelly, K; Münz, C (2008). Patients with Epstein Barr virus-positive lymphomas have decreased CD4(+) T-cell responses to the viral nuclear antigen 1. International Journal of Cancer, 123(12):2824-2831.
Münz, C (2008). Projection of an immunological self shadow to developing T cells via macroautophagy. Cell Research, 18(11):1084-1086.
Gurer, C; Strowig, T; Brilot, F; Pack, M; Trumpfheller, C; Arrey, F; Park, C G; Steinman, R M; Münz, C (2008). Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. Blood, 112(4):1231-1239.
Goebels, Norbert; Becher, Burkhard (2008). Therapeutic antibodies in multiple sclerosis. Neurodegenerative Diseases, 5(1):5-7.
Vince, James E; Chau, D; Callus, Bernard; Wong, W Wei-Lynn; Hawkins, C J; Schneider, P; McKinlay, M; Benetatos, C A; Condon, S M; Chunduru, S K; Yeoh, G; Brink, R; Vaux, David L; Silke, John (2008). Tweak-FN14 signaling induces lysosomal degradation of a cIAP1/TRAF2 complex to sensitize tumour cells to TNFα. Journal of Cell Biology, 182(1):171-184.
Kolas, Nadine K; Chapman, J Ross; Nakada, Shinichiro; Ylanko, Jarkko; Chahwan, Richard; Sweeney, Frédéric D; Panier, Stephanie; Mendez, Megan; Wildenhain, Jan; Thomson, Timothy M; Pelletier, Laurence; Jackson, Stephen P; Durocher, Daniel (2007). Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science, 318(5856):1637-1640.
Wong, W Wei-Lynn; Clendening, J W; Martirosyan, A; Boutros, P C; Bros, C; Khosravi, F; Jurisica, I; Stewart, A K; Bergsagel, P L; Penn, L Z (2007). Determinants of sensitivity to lovastatin-induced apoptosis in multiple myeloma. Molecular Cancer Therapeutics, 6(6):1886-1897.
Steed, A; Buch, T; Waisman, A; Virgin, H W (2007). Gamma interferon blocks gammaherpesvirus reactivation from latency in a cell type-specific manner. Journal of Virology, 81(11):6134-6140.
Vince, J E; Wong, W Wei-Lynn; Khan, N; Feltham, R; Chau, D; Ahmed, A U; Benetatos, C A; Chunduru, S K; Condon, S M; McKinlay, M; Brink, R; Leverkus, M; Tergaonkar, V; Schneider, P; Callus, B A; Koentgen, F; Vaux, David L; Silke, John (2007). IAP antagonists target cIAP1 to induce TNFα-dependent apoptosis. Cell, 131(4):682-693.
Schildknecht, A; Miescher, I; Yagita, Hideo; van den Broek, Maries (2007). Priming of CD8+ T cell responses by pathogens typically depends on CD70-mediated interactions with dendritic cells. European Journal of Immunology, 37:716-728.
Betts, G; Twohig, J; van den Broek, Maries; Sierro, Sophie; Godkin, A; Gallimore, Awen (2007). The impact of regulatory T cells on carcinogen-induced sarcogenesis. British Journal of Cancer, 96:1849-1854.
Langheinrich, Alexander C; Kampschulte, Marian; Buch, Thomas; Bohle, Rainer M (2007). Vasa vasorum and atherosclerosis - Quid novi? Thrombosis and Haemostasis, 97(6):873-879.
van den Broek, Maries; Martinic, M; Rülicke, Thomas; Huber, C; Odermatt, Bernhard; Reith, Walter; Horvath, E; Zellweger, R; Fink, K; Recher, M; Eschli, B; Hengartner, Hans; Zinkernagel, R M (2006). Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC. Proceedings of the National Academy of Sciences of the United States of America:14435-14440.
Gerondakis, S; Grumont, R; Gugasyan, R; Wong, W W L; Isomura, I; Ho, W; Banerjee, A (2006). Unravelling the complexities of the NF-κB signalling pathway using mouse knockout and transgenic models. Oncogene, 25(51):6781-6799.
Freigang, Stefan; Probst, Hans Christian; van den Broek, Maries (2005). DC infection promotes antiviral CTL priming: the 'Winkelried' strategy. Trends in Immunology, 26(1):13-18.
Basta, S; Stoessel, R; Basler, M; van den Broek, Maries; Groettrup, Marcus (2005). Cross-presentation of the long-lived lymphocytic choriomeningitis virus nucleoprotein does not require neosynthesis and is enhanced via heat shock proteins. Journal of Immunology:796-805.
Griffiths, R; Wong, W Wei-Lynn; Fletcher, S P; Penn, L Z; Langler, R F (2005). Novel disulfides with antitumor efficacy and specificity. Australian Journal of Chemistry, 58:128-136.
Probst, Hans Christian; van den Broek, Maries (2005). Priming of CTLs by lymphocytic choriomeningitis virus depends on dendritic cells. Journal of Immunology:3920-3924.
Probst, H C; McCoy, K; Okazaki, T; Honjo, T; van den Broek, Maries (2005). Resting dendritic cells induce peripheral CD8+ T cell tolerance in vivo through PD-1 and CTLA-4. Nature Immunology, 6:280-286.
McPherson, John Peter; Lemmers, Bénédicte; Chahwan, Richard; Pamidi, Ashwin; Migon, Eva; Matysiak-Zablocki, Elzbieta; Moynahan, Mary Ellen; Essers, Jeroen; Hanada, Katsuhiro; Poonepalli, Anuradha; Sanchez-Sweatman, Otto; Khokha, Rama; Kanaar, Roland; Jasin, Maria; Hande, M Prakash; Hakem, Razqallah (2004). Involvement of mammalian Mus81 in genome integrity and tumor suppression. Science, 304(5678):1822-1826.
Wu, J; Wong, W Wei-Lynn; Khosravi, F; Minden, M; Penn, L Z (2004). Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis. Cancer Research, 64:6461-6468.
Basler, M; Youhnovski, N; van den Broek, Maries; Prybylski, M; Groettrup, Marcus (2004). Immunoproteasomes down-regulate presentation of a subdominant T cell epitope from lymphocytic choriomeningitis virus. Journal of Immunology:3925-3934.
Abraham, Jacinth; Lemmers, Bénédicte; Hande, M Prakash; Moynahan, Mary Ellen; Chahwan, Charly; Ciccia, Alberto; Essers, Jeroen; Hanada, Katsuhiro; Chahwan, Richard; Khaw, Aik Kia; McPherson, Peter; Shehabeldin, Amro; Laister, Rob; Arrowsmith, Cheryl; Kanaar, Roland; West, Stephen C; Jasin, Maria; Hakem, Razqallah (2003). Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells. The EMBO Journal, 22(22):6137-47.
Probst, Hans Christian; Tschannen, Kathrin; Gallimore, Awen; Martinic, Marianne; Basler, Michael; Dumrese, Tilman; Jones, Emma; van den Broek, Maries F (2003). Immunodominance of an antiviral cytotoxic T cell response is shaped by the kinetics of viral protein expression. Journal of Immunology, 171(10):5415-5422.
Probst, Hans Christian; Lagnel, Jacques; Kollias, George; van den Broek, Maries (2003). Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance. Immunity, 18(5):713-720.
Mao, D Y L; Watson, J D; Yan, P S; Barsyte-Lovejoy, D; Khosravi, F; Wong, W Wei-Lynn; Farnham, P J; Huang, T H-M; Penn, L Z (2003). Analysis of myc bound loci identified by CpG island arrays shows that max is essential for Myc-dependent repression. Current Biology, 13(10):882-886.
Hangartner, L; Senn, B M; Ledermann, B; Kalinke, U; Seiler, P; Bucher, E; Zellweger, R M; Fink, K; Odermatt, B; Bürki, K; Zinkernagel, R M; Hengartner, H (2003). Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodies. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 100(22):12883-12888.
Probst, Hans Christian; Dumrese, Tilman; van den Broek, Maries F (2002). Cutting edge: competition for APC by CTLs of different specificities is not functionally important during induction of antiviral responses. Journal of Immunology, 168(11):5387-5391.
Wong, W W L; Dimitroulakos, J; Minden, M D; Penn, L Z (2002). HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis. Leukemia, 16(4):508-519.
Khan, S; van den Broek, M; Schwarz, K; de Giuli, R; Diener, P A; Groettrup, M (2001). Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver. Journal of Immunology, 167(12):6859-6868.
Leung, Ray K M; Thomson, K; Gallimore, A; Jones, E; Van den Broek, M; Sierro, S; Alsheikhly, A R; McMichael, A; Rahemtulla, A (2001). Deletion of the CD4 silencer element supports a stochastic mechanism of thymocyte lineage commitment. Nature Immunology, 2(12):1167-1173.
Khan, S; de Giuli, R; Schmidtke, G; Bruns, M; Buchmeier, M; van den Broek, M; Groettrup, M (2001). Cutting edge: neosynthesis is required for the presentation of a T cell epitope from a long-lived viral protein. Journal of Immunology, 167(9):4801-4804.
Xia, Z; Tan, M M; Wong, W Wei-Lynn; Dimitroulakos, J; Minden, M D; Penn, L Z (2001). Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells. Leukemia, 15(9):1398-1407.
Wong, W Wei-Lynn; Tan, M M; Xia, Z; Dimitroualakos, J; Minden, M; Penn, L Z (2001). Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin. Clinical Cancer Research, 7(7):2067-2075.
Matar, Ghassan M; Chahwan, Richard; Fuleihan, Nabil; Uwaydah, Marwan; Hadi, Usamah (2001). PCR-Based Detection, Restriction Endonuclease Analysis, and Transcription of tonB in Haemophilus influenzae and Haemophilus parainfluenzae Isolates Obtained from Children Undergoing Tonsillectomy and Adenoidectomy. Clinical and Diagnostic Laboratory Immunology, 8(2):221-224.
Groettrup, M; van den Broek, M; Schwarz, K; Macagno, A; Khan, S; de Giuli, R; Schmidtke, G (2001). Structural plasticity of the proteasome and its function in antigen processing. Critical Reviews in Immunology, 21(4):339-358.
van den Broek, M F; Hengartner, H (2000). The role of perforin in infections and tumour surveillance. Experimental Physiology, 85(6):681-685.
Schwarz, K; van den Broek, Maries; Kostka, S; Kraft, R; Soza, A; Schmidtke, G; Kloetzel, P M; Groettrup, M (2000). Overexpression of the proteasome subunits LMP2, LMP7, and MECL-1, but not PA28 alpha/beta, enhances the presentation of an immunodominant lymphocytic choriomeningitis virus T cell epitope. Journal of Immunology, 165(2):768-778.
Schwarz, K; de Giuli, R; Schmidtke, G; Kostka, S; van den Broek, M; Kim, K B; Crews, C M; Kraft, R; Groettrup, M (2000). The selective proteasome inhibitors lactacystin and epoxomicin can be used to either up- or down-regulate antigen presentation at nontoxic doses. Journal of Immunology, 164(12):6147-6157.
Wirth, S; van den Broek, M; Frossard, C P; Hügin, A W; Leblond, I; Pircher, H; Hauser, C (2000). CD8(+) T cells secreting type 2 lymphokines are defective in protection against viral infection. Cellular Immunology, 202(1):13-22.
Schwarz, K; van den Broek, M; de Giuli, R; Seelentag, W W; Shastri, N; Groettrup, M (2000). The use of LCMV-specific T cell hybridomas for the quantitative analysis of MHC class I restricted antigen presentation. Journal of Immunological Methods, 237(1-2):199-202.
van den Broek, Maries; Bachmann, M F; Köhler, G; Barner, M; Escher, R; Zinkernagel, R; Kopf, M (2000). IL-4 and IL-10 antagonize IL-12-mediated protection against acute vaccinia virus infection with a limited role of IFN-gamma and nitric oxide synthetase 2. Journal of Immunology, 164(1):371-378.
Wong, W W L; Macdonald, S; Langler, R F; Penn, L Z (2000). Novel synthetic organosulfur compounds induce apoptosis of human leukemic cells. Anticancer Research, 20(3a):1367-1374.
Grob, P; Schijns, V E; van den Broek, M F; Cox, S P; Ackermann, M; Suter, M (1999). Role of the individual interferon systems and specific immunity in mice in controlling systemic dissemination of attenuated pseudorabies virus infection. Journal of Virology, 73(6):4748-4754.
Betz, U A; Bloch, W; van den Broek, M; Yoshida, K; Taga, T; Kishimoto, T; Addicks, K; Rajewsky, K; Müller, W (1998). Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects. Journal of Experimental Medicine, 188(10):1955-1965.
Gallimore, A; Schwarz, K; van den Broek, M; Hengartner, H; Groettrup, M (1998). The proteasome inhibitor lactacystin prevents the generation of an endoplasmic reticulum leader-derived T cell epitope. Molecular Immunology, 35(10):581-91.
Binder, D; van den Broek, M F; Kägi, D; Bluethmann, H; Fehr, J; Hengartner, H; Zinkernagel, R M (1998). Aplastic anemia rescued by exhaustion of cytokine-secreting CD8+ T cells in persistent infection with lymphocytic choriomeningitis virus. Journal of Experimental Medicine, 187(11):1903-1920.
Van den Broek, M F; Kägi, D; Hengartner, H (1998). Effector pathways of natural killer cells. Current topics in microbiology and immunology, 230:123-131.
van den Broek, M F; Spörri, R; Even, C; Plagemann, P G; Hänseler, E; Hengartner, H; Zinkernagel, R M (1997). Lactate dehydrogenase-elevating virus (LDV): lifelong coexistence of virus and LDV-specific immunity. Journal of Immunology, 159(4):1585-1588.
van den Broek, M F; Kägi, D; Ossendorp, F; Toes, R; Vamvakas, S; Lutz, W K; Melief, C J M; Zinkernagel, R M; Hengartner, H (1996). Decreased tumor surveillance in perforin-deficient mice. Journal of Experimental Medicine, 184(5):1781-1790.
van den Broek, M F; Müller, U; Huang, S; Zinkernagel, R M; Aguet, M (1995). Immune defence in mice lacking type I and/or type II interferon receptors. Immunological Reviews, 148:4792-4796.
van den Broek, M F; Kägi, D; Zinkernagel, R M; Hengartner, H (1995). Perforin dependence of natural killer cell-mediated tumor control in vivo. European Journal of Immunology, 25(12):3514-3516.
van den Broek, M F; Müller, U; Huang, S; Aguet, M; Zinkernagel, R M (1995). Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors. Journal of Virology, 69(8):4792-4796.
Moskophidis, D; Battegay, M; van den Broek, M; Laine, E; Hoffmann-Rohrer, U; Zinkernagel, R M (1995). Role of virus and host variables in virus persistence or immunopathological disease caused by a non-cytolytic virus. Journal of General Virology, 76/ 2:381-391.
