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Kong, Yanyan; Cao, Lei; Xie, Fang; Wang, Xiuzhe; Zuo, Chuantao; Shi, Kuangyu; Rominger, Axel; Huang, Qi; Xiao, Jianfei; Jiang, Donglang; Guan, Yihui; Ni, Ruiqing (2024). Reduced SV2A and GABA$_A$ receptor levels in the brains of type 2 diabetic rats revealed by [$^{18}$F]SDM-8 and [$^{18}$F]flumazenil PET. Biomedicine & Pharmacotherapy, 172:116252.

Rodríguez Peris, Laura; Scheuber, Myriam Ilona; Shan, Huimin; Braun, Marie; Schwab, Martin E (2024). Barnes maze test for spatial memory: A new, sensitive scoring system for mouse search strategies. Behavioural Brain Research, 458:114730.

Valdivia-Francia, Fabiola; Sendoel, Ataman (2024). No country for old methods: new tools for studying microproteins. iScience, 27(2):108972.

Rust, Ruslan; Tackenberg, Christian (2024). Stem Cell Therapy for Repair of the Injured Brain: Five Principles. The Neuroscientist, 30(1):10-16.

Peter, Nicole; Treyer, Valerie; Probst, Rudolf; Kleinjung, Tobias (2024). Auditory Cortical Plasticity in Patients with Single-Sided Deafness Before and After Cochlear Implantation. Journal of the Association for Research in Otolaryngology (JARO):Epub ahead of print.

Kagerer, Sonja M; Awasthi, Swapnil; Ripke, Stephan; Maceski, Aleksandra; Benkert, Pascal; Fall, Aïda B; Riederer, Peter; Fischer, Peter; Walitza, Susanne; Grünblatt, Edna; Kuhle, Jens; Unschuld, Paul G (2024). Polygenic risk for Alzheimer’s disease is associated with neuroaxonal damage before onset of clinical symptoms. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 16(1):e12504.

Cao, Lei; Ji, Bin; Ni, Ruiqing (2024). Advances in non-invasive imaging of proteinopathies in animal models of neurodegenerative diseases. Neural Regeneration Research, 19(10):2115-2116.

Mrđenović, Dušan; Combes, Benjamin F; Ni, Ruiqing; Zenobi, Renato; Kumar, Naresh (2024). Probing Chemical Complexity of Amyloid Plaques in Alzheimer's Disease Mice using Hyperspectral Raman Imaging. ACS Chemical Neuroscience, 15(1):78-85.


Gericke, Christoph; Kirabali, Tunahan; Flury, Roman; Mallone, Anna; Rickenbach, Chiara; Kulic, Luka; Tosevski, Vinko; Hock, Christoph; Nitsch, Roger M; Treyer, Valerie; Ferretti, Maria Teresa; Gietl, Anton (2023). Early β-amyloid accumulation in the brain is associated with peripheral T cell alterations. Alzheimer's & Dementia, 19(12):5642-5662.

Hood, Rebecca J; Sanchez-Bezanilla, Sonia; Beard, Daniel J; Rust, Ruslan; Turner, Renée J; Stuckey, Shannon M; Collins-Praino, Lyndsey E; Walker, Frederick R; Nilsson, Michael; Ong, Lin Kooi (2023). Leakage beyond the primary lesion: A temporal analysis of cerebrovascular dysregulation at sites of hippocampal secondary neurodegeneration following cortical photothrombotic stroke. Journal of Neurochemistry, 167(6):733-752.

Weber, Rebecca Zoe. Stem Cell Therapy for Stroke Recovery. 2023, University of Zurich, Faculty of Science.

Scheuber, Myriam I.. Therapeutic Approaches to Improve Regeneration and Functional Recovery after CNS Injuries in Pre-Clinical Rodent Models. 2023, University of Zurich, Faculty of Science.

Rust, Ruslan; Holm, Mea M; Egger, Matteo; Weinmann, Oliver; van Rossum, Daniёlle; Walter, Fruzsina R; Santa-Maria, Ana Raquel; Grönnert, Lisa; Maurer, Michael A; Kraler, Simon; Akhmedov, Alexander; Cideciyan, Rose; Lüscher, Thomas F; Deli, Maria A; Herrmann, Inge K; Schwab, Martin E (2023). Nogo-A is secreted in extracellular vesicles, occurs in blood and can influence vascular permeability. Journal of Cerebral Blood Flow and Metabolism:Epub ahead of print.

Hirch, Tanja; Brander, Nadine; Schenk, Franziska; Pöllmann, Simon J; Reichenbach, Janine; Schubert, Ralf; Modlich, Ute (2023). Expression of a large coding sequence: Gene therapy vectors for Ataxia Telangiectasia. Scientific Reports, 13(1):19386.

Wirth, Fabian; Heitz, Fabrice D; Seeger, Christine; Combaluzier, Ioana; Breu, Karin; Denroche, Heather C; Thevenet, Julien; Osto, Melania; Arosio, Paolo; Kerr-Conte, Julie; Verchere, C Bruce; Pattou, François; Lutz, Thomas A; Donath, Marc Y; Hock, Christoph; Nitsch, Roger M; Grimm, Jan (2023). A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models. Nature Communications, 14(1):6294.

Emmert, Maximilian Y; Burrello, Jacopo; Wolint, Petra; Hilbe, Monika; Andriolo, Gabriella; Balbi, Carolina; Provasi, Elena; Turchetto, Lucia; Radrizzani, Marina; Nazari-Shafti, Timo Z; Cesarovic, Nikola; Neuber, Sebastian; Falk, Volkmar; Hoerstrup, Simon P; Hemetsberger, Rayyan; Gyöngyösi, Mariann; Barile, Lucio; Vassalli, Giuseppe (2023). Intracoronary delivery of extracellular vesicles from human cardiac progenitor cells reduces infarct size in porcine acute myocardial infarction. European Heart Journal:Epub ahead of print.

Zaytseva, Polina; Visser, Valery L; Ehterami, Arian; Hoerstrup, Simon P; Motta, Sarah E; Emmert, Maximilian Y (2023). Xenogeneic Serum‐Free Human Cell‐Derived Tissue Engineered Matrices for the Development of Clinical‐Grade Biomimetic Cardiovascular Devices. Advanced Therapeutics, 6(10):2300041.

Ghoshdastider, Umesh; Sendoel, Ataman (2023). Exploring the pan-cancer landscape of posttranscriptional regulation. Cell Reports, 42(10):113172.

Nazari-Shafti, Timo Z; Thau, Henriette; Zacharova, Ema; Beez, Christien M; Exarchos, Vasileios; Neuber, Sebastian; Meyborg, Heike; Puhl, Kerstin; Wittig, Corey; Szulcek, Robert; Neumann, Konrad; Giampietro, Costanza; Krüger, Katrin; Cesarovic, Nikola; Falk, Volkmar; Caliskan, Etem; Biefer, Hector Rodriguez Cetina; Emmert, Maximilian Y (2023). Endothelial damage inhibitor preserves the integrity of venous endothelial cells from patients undergoing coronary bypass surgery. European Journal of Cardio-Thoracic Surgery, 64(6):ezad327.

Martinez-Navajas, Gonzalo; Ceron-Hernandez, Jorge; Simon, Iris; Lupiañez, Pablo; Diaz-McLynn, Sofia; Perales, Sonia; Modlich, Ute; Guerrero, Jose A; Martin, Francisco; Sevivas, Teresa; Lozano, Maria L; Rivera, Jose; Ramos-Mejia, Veronica; Tersteeg, Claudia; Real, Pedro J (2023). Lentiviral gene therapy reverts GPIX expression and phenotype in Bernard-Soulier syndrome type C. Molecular Therapy - Nucleic Acids, 33:75-92.

Le Guen, Yann; Luo, Guo; Ambati, Aditya; Damotte, Vincent; Jansen, Iris; Yu, Eric; Nicolas, Aude; de Rojas, Itziar; Peixoto Leal, Thiago; Miyashita, Akinori; Bellenguez, Céline; Lian, Michelle Mulan; Parveen, Kayenat; Morizono, Takashi; Park, Hyeonseul; Grenier-Boley, Benjamin; Naito, Tatsuhiko; Küçükali, Fahri; Talyansky, Seth D; Yogeshwar, Selina Maria; Sempere, Vicente; Satake, Wataru; Alvarez, Victoria; Arosio, Beatrice; Belloy, Michael E; Benussi, Luisa; Boland, Anne; Borroni, Barbara; Bullido, María J; Caffarra, Paolo; Grünblatt, Edna; et al; Popp, Julius (2023). Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes. Proceedings of the National Academy of Sciences of the United States of America, 120(36):e2302720120.

Zaytseva, Polina. Development, Characterization and Validation of Xenogeneic Serum-Free Tissue Engineered Matrices for Cardiovascular Applications. 2023, University of Zurich, Faculty of Science.

Shan, Hui-Min; Maurer, Michael A; Schwab, Martin E (2023). Four-parameter analysis in modified Rotarod test for detecting minor motor deficits in mice. BMC Biology, 21(1):177.

Bachmann, Dario; Buchmann, Andreas; Studer, Sandro; Saake, Antje; Rauen, Katrin; Zuber, Isabelle; Gruber, Esmeralda; Nitsch, Roger M; Hock, Christoph; Gietl, Anton; Treyer, Valerie (2023). Age-, sex-, and pathology-related variability in brain structure and cognition. Translational Psychiatry, 13(1):278.

Ni, Ruiqing; Straumann, Nadja; Fazio, Serana; Dean-Ben, Xose Luis; Louloudis, Georgios; Keller, Claudia; Razansky, Daniel; Ametamey, Simon; Mu, Linjing; Nombela-Arrieta, César; Klohs, Jan (2023). Imaging increased metabolism in the spinal cord in mice after middle cerebral artery occlusion. Photoacoustics, 32:100532.

Fan, Zheng; Ardicoglu, Raphaela; Batavia, Aashil A; Rust, Ruslan; von Ziegler, Lukas; Waag, Rebecca; Zhang, Jing; Desgeorges, Thibaut; Sturman, Oliver; Dang, Hairuo; Weber, Rebecca; Roszkowski, Martin; Moor, Andreas E; Schwab, Martin E; Germain, Pierre-Luc; Bohacek, Johannes; De Bock, Katrien (2023). The vascular gene Apold1 is dispensable for normal development but controls angiogenesis under pathological conditions. Angiogenesis, 26(3):385-407.

Peretti, Débora E; Ribaldi, Federica; Scheffler, Max; Mu, Linjing; Treyer, Valerie; Gietl, Anton F; Hock, Christoph; Frisoni, Giovanni B; Garibotto, Valentina (2023). ATN profile classification across two independent prospective cohorts. Frontiers in Medicine, 10:1168470.

Garcia-Pavia, Pablo; Aus dem Siepen, Fabian; Donal, Erwan; Lairez, Olivier; van der Meer, Peter; Kristen, Arnt V; Mercuri, Michele F; Michalon, Aubin; Frost, Robert J A; Grimm, Jan; Nitsch, Roger M; Hock, Christoph; Kahr, Peter C; Damy, Thibaud (2023). Phase 1 Trial of Antibody NI006 for Depletion of Cardiac Transthyretin Amyloid. New England Journal of Medicine, 389(3):239-250.

Cesarovic, Nikola; Weisskopf, Miriam; Stolte, Thorald; Trimmel, Nina; Hierweger, Melanie M; Hoh, Tobias; Iske, Jasper; Waschkies, Conny; Chen, Jia Lu; van Gelder, Eva; Leuthardt, Andrea; Glaus, Lukas; Rösch, Yannick; Stoeck, Christian T; Wolint, Petra; Obrist, Dominik; Kozerke, Sebastian; Falk, Volkmar; Emmert, Maximilian Y (2023). Development of a Translational Autologous Microthrombi-Induced MINOCA Pig Model. Circulation Research, 133(3):291-293.

Prétot, Dominique; Engel-Bicik, Ivette; Kenkel, David; Kaufmann, Philipp A; Treyer, Valerie; Siebenhüner, Alexander R (2023). Outcome analysis in patients with metastatic gastroenteropancreatic neuroendocrine tumors receiving peptide receptor radionuclide therapy with Lu-177-DOTATATE. Journal of Gastrointestinal Oncology, 14(3):1204-1217.

Straumann, Nadja; Combes, Benjamin F; Ben, Xose Luis Dean; Sternke-Hoffmann, Rebecca; Gerez, Juan A; Dias, Ines; Chen, Zhenyue; Watts, Benjamin; Rostami, Iman; Shi, Kuangyu; Rominger, Axel; Baumann, Christian R; Luo, Jinghui; Noain, Daniela; Nitsch, Roger M; Okamura, Nobuyuki; Razansky, Daniel; Ni, Ruiqing (2023). Visualizing alpha-synuclein and iron deposition in M83 mouse model of Parkinson's disease in vivo. bioRxiv 546962, Cold Spring Harbor Laboratory.

Neuber, Sebastian; Ermer, Miriam R; Emmert, Maximilian Y; Nazari-Shafti, Timo Z (2023). Treatment of Cardiac Fibrosis with Extracellular Vesicles: What Is Missing for Clinical Translation? International Journal of Molecular Sciences, 24(13):10480.

Rust, Ruslan (2023). Ischemic stroke-related gene expression profiles across species: a meta-analysis. Journal of Inflammation, 20(1):21.

Motta, Sarah E; Peters, Michael M; Chantre, Christophe O; Chang, Huibin; Cera, Luca; Liu, Qihan; Cordoves, Elizabeth M; Fioretta, Emanuela S; Zaytseva, Polina; Cesarovic, Nikola; Emmert, Maximilian Y; Hoerstrup, Simon P; Parker, Kevin Kit (2023). On-demand heart valve manufacturing using focused rotary jet spinning. Matter, 6(6):1860-1879.

Leiter, Odette; Zhuo, Zhan; Rust, Ruslan; Wasielewska, Joanna M; Grönnert, Lisa; Kowal, Susann; Overall, Rupert W; Adusumilli, Vijay S; Blackmore, Daniel G; Southon, Adam; Ganio, Katherine; McDevitt, Christopher A; Rund, Nicole; Brici, David; Mudiyan, Imesh Aththanayake; Sykes, Alexander M; Rünker, Annette E; Zocher, Sara; Ayton, Scott; Bush, Ashley I; Bartlett, Perry F; Hou, Sheng-Tao; Kempermann, Gerd; Walker, Tara L (2023). Correction: Selenium mediates exercise-induced adult neurogenesis and reverses learning deficits induced by hippocampal injury and aging. Cell Metabolism, 35(6):1085.

Motta, Sarah E; Breuer, Christopher K; Zilla, Peter; Hoerstrup, Simon P; Emmert, Maximilian Y (2023). Evaluating Calcification in Tissue-Engineered Heart Valves: Much More Complicated Than Expected? JACC: Basic to Translational Science, 8(5):592-593.

Kecheliev, Vasil; Boss, Leo; Maheshwari, Upasana; Konietzko, Uwe; Keller, Annika; Razansky, Daniel; Nitsch, Roger M; Klohs, Jan; Ni, Ruiqing (2023). Aquaporin 4 is differentially increased and dislocated in association with tau and amyloid-beta. Life Sciences, 321:121593.

Alchera, Nicola; Garibotto, Valentina; Tomczyk, Szymon; Treyer, Valerie; Hock, Christoph; Gietl, Anton F; Lövblad, Karl-Olof; Scheffler, Max; Chincarini, Andrea; Frisoni, Giovanni B; Ribaldi, Federica (2023). Patterns of amyloid accumulation in amyloid-negative cases. Neurobiology of Aging, 129:99-108.

Schwartzman, William E; Jimenez, Michael; Yates, Andrew R; Armstrong, Aimee K; Salavitabar, Arash; Hor, Kan K; Hoerstrup, Simon; Emmert, Maximilian Y; Shinoka, Toshiharu; Carrillo, Sergio A; Breuer, Christopher K; Kelly, John M (2023). Patch Materials for Pulmonary Artery Arterioplasty and Right Ventricular Outflow Tract Augmentation: A Review. Pediatric Cardiology, 44(5):973-995.

Magkoutas, Konstantinos; Weisskopf, Miriam; Falk, Volkmar; Emmert, Maximilian Y; Meboldt, Mirko; Cesarovic, Nikola; Schmid Daners, Marianne (2023). Continuous Monitoring of Blood Pressure and Vascular Hemodynamic Properties With Miniature Extravascular Hall-Based Magnetic Sensor. JACC: Basic to Translational Science, 8(5):546-564.

Siow, Kah Mun. Development of a CRISPR-Based Knock-In Gene Therapy Strategy for P47phox-Deficient Chronic Granulomatous Disease. 2023, University of Zurich, Faculty of Science.

Shan, Hui-Min; Schwab, Martin E; Maurer, Michael A (2023). Development of a Sensitive Enzyme-Linked Immunosorbent Assay with Three Amplification Antibodies to Detect Low-Abundant Mouse Antibodies in the Mouse Central Nervous System. Journal of Immunology, 210(7):1004-1010.

Rust, Ruslan (2023). Rebooting disruptive science: Exploring the challenges and potential solutions. European Journal of Clinical Investigation:e13988.

Zhang, Junhao; Treyer, Valerie; Sun, Junfeng; Zhang, Chencheng; Gietl, Anton; Hock, Christoph; Razansky, Daniel; Nitsch, Roger M; Ni, Ruiqing (2023). Automatic analysis of skull thickness, scalp-to-cortex distance and association with age and sex in cognitively normal elderly. Brain Stimulation, 16(2):653-656.

Martin, Marcy; Gähwiler, Eric K N; Generali, Melanie; Hoerstrup, Simon P; Emmert, Maximilian Y (2023). Advances in 3D Organoid Models for Stem Cell-Based Cardiac Regeneration. International Journal of Molecular Sciences, 24(6):5188.

Martin, Marcy; Motta, Sarah E; Emmert, Maximilian Y (2023). Have we found the missing link between inflammation, fibrosis, and calcification in calcific aortic valve disease? European Heart Journal, 44(10):899-901.

Achón Buil, Beatriz; Tackenberg, Christian; Rust, Ruslan (2023). Editing a gateway for cell therapy across the blood-brain barrier. Brain: a journal of neurology, 146(3):823-841.

Poulis, N; Breitenstein, P; Hofstede, S; Hoerstrup, S P; Emmert, M Y; Fioretta, E S (2023). Multiscale analysis of human tissue engineered matrices for heart valve tissue engineering applications. Acta Biomaterialia, 158:101-114.

Casanova, Elisa A; Rodriguez-Palomo, Adrian; Stähli, Lisa; Arnke, Kevin; Gröninger, Olivier; Generali, Melanie; Neldner, Yvonne; Tiziani, Simon; Dominguez, Ana Perez; Guizar-Sicairos, Manuel; Gao, Zirui; Appel, Christian; Nielsen, Leonard C; Georgiadis, Marios; Weber, Franz E; Stark, Wendelin; Pape, Hans-Christoph; Cinelli, Paolo; Liebi, Marianne (2023). SAXS imaging reveals optimized osseointegration properties of bioengineered oriented 3D-PLGA/aCaP scaffolds in a critical size bone defect model. Biomaterials, 294:121989.

Chen, Mary Jialu; Pappas, Georgios A; Massella, Daniele; Schlothauer, Arthur; Motta, Sarah E; Falk, Volkmar; Cesarovic, Nikola; Ermanni, Paolo (2023). Tailoring crystallinity for hemocompatible and durable PEEK cardiovascular implants. Biomaterials advances, 146:213288.

Weber, Ramona; Ghoshdastider, Umesh; Spies, Daniel; Duré, Clara; Valdivia-Francia, Fabiola; Forny, Merima; Ormiston, Mark; Renz, Peter F; Taborsky, David; Yigit, Merve; Bernasconi, Martino; Yamahachi, Homare; Sendoel, Ataman (2023). Monitoring the 5'UTR landscape reveals isoform switches to drive translational efficiencies in cancer. Oncogene, 42(9):638-650.

Motta, Sarah E; Martin, Marcy; Gähwiler, Eric K N; Visser, Valery L; Zaytseva, Polina; Ehterami, Arian; Hoerstrup, Simon P; Emmert, Maximilian Y (2023). Combining Cell Technologies With Biomimetic Tissue Engineering Applications: A New Paradigm for Translational Cardiovascular Therapies. Stem Cells Translational Medicine, 12(2):72-82.

Tackenberg, Christian. Cell models for the analysis of pathomechanisms in Alzheimer's disease. 2023, University of Zurich, Faculty of Medicine.

Ren, Wuwei; Deán-Ben, Xosé Luís; Skachokova, Zhiva; Augath, Mark-Aurel; Ni, Ruiqing; Chen, Zhenyue; Razansky, Daniel (2023). Monitoring mouse brain perfusion with hybrid magnetic resonance optoacoustic tomography. Biomedical Optics Express, 14(3):1192-1204.

Grünblatt, Edna; Homolak, Jan; Babic Perhoc, Ana; Davor, Virag; Knezovic, Ana; Osmanovic Barilar, Jelena; Riederer, Peter; Walitza, Susanne; Tackenberg, Christian; Salkovic-Petrisic, Melita (2023). From attention-deficit hyperactivity disorder to sporadic Alzheimer’s disease—Wnt/mTOR pathways hypothesis. Frontiers in Neuroscience, 17:1104985.

Ni, Ruiqing (2023). PET imaging in animal models of Parkinson's disease. Behavioural Brain Research, 438:114174.

Ulku, Irem; Liebsch, Filip; Akerman, S Can; Schulz, Jana F; Kulic, Luka; Hock, Christoph; Pietrzik, Claus; Di Spiezio, Alessandro; Thinakaran, Gopal; Saftig, Paul; Multhaup, Gerhard (2023). Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis. Scientific Reports, 13(1):2216.

Zhang, Junhao; Treyer, Valerie; Sun, Junfeng; Zhang, Chencheng; Gietl, Anton; Hock, Christoph; Razansky, Daniel; Nitsch, Roger M; Ni, Ruiqing (2023). Automatic analysis of skull thickness, scalp-to-cortex distance and association with age and sex in cognitively normal elderly. bioRxiv 524484, Cold Spring Harbor Laboratory.

Ni, Ruiqing; Deán-Ben, Xosé Luís; Treyer, Valerie; Gietl, Anton; Hock, Christoph; Klohs, Jan; Nitsch, Roger M; Razansky, Daniel (2023). Coregistered transcranial optoacoustic and magnetic resonance angiography of the human brain. Optics letters, 48(3):648-651.

Correa, Daphne; Scheuber, Myriam I; Shan, Huimin; Weinmann, Oliver W; Baumgartner, Yves A; Harten, Aliona; Wahl, Anna-Sophia; Skaar, Kirstin L; Schwab, Martin E (2023). Intranasal delivery of full-length anti-Nogo-A antibody: A potential alternative route for therapeutic antibodies to central nervous system targets. Proceedings of the National Academy of Sciences of the United States of America, 120(4):e2200057120.

Achón Buil, Beatriz; Rust, Ruslan (2023). Preserving stroke penumbra by targeting lipid signalling. Journal of Cerebral Blood Flow and Metabolism, 43(1):167-169.

Rickenbach, Chiara Enrica. Immunophenotyping and functional analysis of Alzheimer's disease-related T cells. 2023, University of Zurich, Faculty of Science.

Poulis, Nikolaos. Multiscale Characterization and Immunocompatibility Assessment of Human Tissue Engineered Matrices for Next Generation Heart Valve Applications. 2023, University of Zurich, Faculty of Science.

Shan, Huimin. Nogo-A Inhibition Combined with Neurorehabilitation - A Novel Regenerative Therapy for Traumatic Brain Injury. 2023, University of Zurich, Faculty of Science.


Jambeau, Melanie; Meyer, Kevin D; Hruska-Plochan, Marian; et al; Cavegn, Nicole; Borter, Petra; De Rossi, Pierre; Pérez-Berlanga, Manuela; Maniecka, Zuzanna; Weber, Julien; Hock, Christoph; Nitsch, Roger M; Petrucelli, Leonard; Gendron, Tania F; Montrasio, Fabio; Grimm, Jan; Polymenidou, Magdalini (2022). Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease. Proceedings of the National Academy of Sciences of the United States of America, 119(49):e2123487119.

Weber, Ramona; Kleemann, Leon; Hirschberg, Insa; Chung, Min-Yi; Valkov, Eugene; Igreja, Cátia (2022). DAP5 enables main ORF translation on mRNAs with structured and uORF-containing 5' leaders. Nature Communications, 13:7510.

Zhang, Jiawei; Liu, Lan; Zhang, Yaxuan; Yuan, Yuan; Miao, Zhijuan; Lu, Kaili; Zhang, Xiaojie; Ni, Ruiqing; Zhang, Haibing; Zhao, Yuwu; Wang, Xiuzhe (2022). ChemR23 signaling ameliorates cognitive impairments in diabetic mice via dampening oxidative stress and NLRP3 inflammasome activation. Redox Biology, 58:102554.

Sartori, Andrea M; Kiss, Bernhard; Mordasini, Livio; Pollo, Claudio; Schüpbach, Michael; Burkhard, Fiona C; Schwab, Martin E; Kaelin-Lang, Alain; Kessler, Thomas M (2022). Effects of Deep Brain Stimulation on Lower Urinary Tract Function in Neurological Patients. European Urology Focus, 8(6):1775-1782.

Lai, Chai Foong; Shen, Juliet; Balic, Anamaria; Pagella, Pierfrancesco; Schwab, Martin E; Mitsiadis, Thimios A (2022). Nogo-A Regulates the Fate of Human Dental Pulp Stem Cells toward Osteogenic, Adipogenic, and Neurogenic Differentiation. Cells, 11(21):3415.

Ni, Ruiqing; Müller Herde, Adrienne; Haider, Ahmed; Keller, Claudia; Louloudis, Georgios; Vaas, Markus; Schibli, Roger; Ametamey, Simon M; Klohs, Jan; Mu, Linjing (2022). In vivo Imaging of Cannabinoid Type 2 Receptors: Functional and Structural Alterations in Mouse Model of Cerebral Ischemia by PET and MRI. Molecular Imaging and Biology, 24(5):700-709.

Hofer, Anna-Sophie; Scheuber, Myriam I; Sartori, Andrea M; Good, Nicolas; Stalder, Stephanie A; Hammer, Nicole; Fricke, Kai; Schalbetter, Sina M; Engmann, Anne K; Weber, Rebecca Zoe; Rust, Ruslan; Schneider, Marc P; Russi, Natalie; Favre, Giacomin; Schwab, Martin E (2022). Stimulation of the cuneiform nucleus enables training and boosts recovery after spinal cord injury. Brain: a journal of neurology, 145(10):3681-3697.

Weber, Rebecca Zoe; Mulders, Geertje; Kaiser, Julia; Tackenberg, Christian; Rust, Ruslan (2022). Deep learning-based behavioral profiling of rodent stroke recovery. BMC Biology, 20:232.

Fernandes, Andreia; Miéville, Arnaud; Grob, Franziska; Yamashita, Tadahiro; Mehl, Julia; Hosseini, Vahid; Emmert, Maximilian Y; Falk, Volkmar; Vogel, Viola (2022). Endothelial-Smooth Muscle Cell Interactions in a Shear-Exposed Intimal Hyperplasia on-a-Dish Model to Evaluate Therapeutic Strategies. Advanced Science, 9(28):e2202317.

Kecheliev, Vasil; Spinelli, Francesco; Herde, Adrienne; Haider, Ahmed; Mu, Linjing; Klohs, Jan; Ametamey, Simon M; Ni, Ruiqing (2022). Evaluation of cannabinoid type 2 receptor expression and pyridine-based radiotracers in brains from a mouse model of Alzheimer's disease. Frontiers in Aging Neuroscience, 14:1018610.

Rust, Ruslan; Weber, Rebecca Z; Generali, Melanie; Kehl, Debora; Bodenmann, Chantal; Uhr, Daniela; Wanner, Debora; Zürcher, Kathrin J; Saito, Hirohide; Hoerstrup, Simon P; Nitsch, Roger M; Tackenberg, Christian (2022). Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications. Journal of Translational Medicine, 20(1):421.

Targosinski, Stefan; Henzi, Anna; Engmann, Anne K; Rushing, Elisabeth J; Barth, André A; Klein, Holger J; Kim, Bong-Sung; Giovanoli, Pietro; Schwab, Martin E; Plock, Jan A; Schweizer, Riccardo (2022). A swim test for functional assessment of rodent peripheral nerve regeneration. Journal of Neuroscience Methods, 379:109663.

Bachmann, Dario; Roman, Zachary J; Buchmann, Andreas; Zuber, Isabelle; Studer, Sandro; Saake, Antje; Rauen, Katrin; Gruber, Esmeralda; Nitsch, Roger M; Hock, Christoph; Gietl, Anton F; Treyer, Valerie (2022). Lifestyle Affects Amyloid Burden and Cognition Differently in Men and Women. Annals of Neurology, 92(3):451-463.

Hu, Yexing; Lafci, Berkan; Luzgin, Artur; Wang, Hao; Klohs, Jan; Dean-Ben, Xose Luis; Ni, Ruiqing; Razansky, Daniel; Ren, Wuwei (2022). Deep learning facilitates fully automated brain image registration of optoacoustic tomography and magnetic resonance imaging. Biomedical Optics Express, 13(9):4817-4833.

Chambel, Sílvia Sousa; Ferreira, Ana; Oliveira, Raquel; Miranda, Rafael; Vale, Luís; Reguenga, Carlos; Schwab, Martin E; Cruz, Célia Duarte (2022). Development of Neurogenic Detrusor Overactivity after Thoracic Spinal Cord Injury Is Accompanied by Time-Dependent Changes in Lumbosacral Expression of Axonal Growth Regulators. International Journal of Molecular Sciences, 23(15):8667.

Ni, Ruiqing; Chen, Zhenyue; Deán-Ben, Xosé Luís; Voigt, Fabian F; Kirschenbaum, Daniel; Shi, Gloria; Villois, Alessia; Zhou, Quanyu; Crimi, Alessandro; Arosio, Paolo; Nitsch, Roger M; Nilsson, K Peter R; Aguzzi, Adriano; Helmchen, Fritjof; Klohs, Jan; Razansky, Daniel (2022). Multiscale optical and optoacoustic imaging of amyloid-β deposits in mice. Nature Biomedical Engineering, 6(9):1031-1044.

Schuster-Amft, Corina; Kool, Jan; Möller, J Carsten; Schweinfurther, Raoul; Ernst, Markus J; Reicherzer, Leah; Ziller, Carina; Schwab, Martin E; Wieser, Simon; Wirz, Markus (2022). Feasibility and cost description of highly intensive rehabilitation involving new technologies in patients with post-acute stroke-a trial of the Swiss RehabTech Initiative. Pilot and Feasibility Studies, 8:139.

Le Guen, Yann; Belloy, Michael E; Grenier-Boley, Benjamin; de Rojas, Itziar; et al; Grünblatt, Edna; Popp, Julius (2022). Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease. JAMA Neurology, 79(7):652-663.

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Ravikumar, Priyanka. Development of Blood-Based Assays for Early Detection of Aβ42 Biomarker in Alzheimer's Disease. 2022, University of Zurich, Faculty of Science.

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Wirth, Adriana Noelle. External Validation of the Modified 4C Deterioration Model and 4C Mortality Score for COVID-19 Patients in a Swiss Tertiary Hospital. 2022, University of Zurich, Faculty of Medicine.

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Raimondi, Federica. Gene Therapy Approaches for ΔGT p47phox-Deficient Chronic Granulomatous Disease (CGD). 2021, University of Zurich, Faculty of Science.

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Frese, Laura; Darwiche, Salim E; von Rechenberg, Brigitte; Hoerstrup, Simon P; Giovanoli, Pietro; Calcagni, Maurizio (2021). Thermal conditioning improves quality and speed of keratinocyte sheet production for burn wound treatment. Cytotherapy, 23(6):536-547.

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Michalon, Aubin; Hagenbuch, Andreas; Huy, Christian; Varela, Evita; Combaluzier, Benoit; Damy, Thibaud; Suhr, Ole B; Saraiva, Maria J; Hock, Christoph; Nitsch, Roger M; Jan Grimm (2021). A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells. Nature Communications, 12(1):3142.

Palau, Vanesa; Nugraha, Bramasta; Benito, David; Pascual, Julio; Emmert, Maximilian Y; Hoerstrup, Simon P; Riera, Marta; Soler, Maria José (2021). Both Specific Endothelial and Proximal Tubular Adam17 Deletion Protect against Diabetic Nephropathy. International Journal of Molecular Sciences, 22(11):5520.

Massalimova, Aidana; Ni, Ruiqing; Nitsch, Roger M; Reisert, Marco; von Elverfeldt, Dominik; Klohs, Jan (2021). Diffusion Tensor Imaging Reveals Whole-Brain Microstructural Changes in the P301L Mouse Model of Tauopathy. Neurodegenerative Diseases, 20(5-6):173-184.

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Schoenrath, Felix; Falk, Volkmar; Emmert, Maximilian Y (2021). Xenotransplantation in the era of a zoonotic pandemic. European Heart Journal, 42(14):1283-1285.

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Rust, Ruslan (2021). Towards blood biomarkers for stroke patients. Journal of Cerebral Blood Flow and Metabolism, 41(4):914-916.

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Clark, Christopher; Lewczuk, Piotr; Kornhuber, Johannes; Richiardi, Jonas; Maréchal, Bénédicte; Karikari, Thomas K; Blennow, Kaj; Zetterberg, Henrik; Popp, Julius (2021). Plasma neurofilament light and phosphorylated tau 181 as biomarkers of Alzheimer's disease pathology and clinical disease progression. Alzheimer's Research & Therapy, 13(1):65.

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Jahn, Tabea; Clark, Christopher; Kerksiek, Anja; Lewczuk, Piotr; Lütjohann, Dieter; Popp, Julius (2021). Cholesterol metabolites and plant sterols in cerebrospinal fluid are associated with Alzheimer's cerebral pathology and clinical disease progression. Journal of Steroid Biochemistry and Molecular Biology, 205:105785.

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Generali, Melanie. Reprogramming of human PBMCs into iPSCs for the In-vitro manufacture of engineered vascular grafts based on biodegradable synthetic polymers. 2017, University of Zurich, Faculty of Science.

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Ben Halima, Saoussen; Mishra, Sabyashachi; Raja, K Muruga Poopathi; Willem, Michael; Baici, Antonio; Simons, Kai; Brüstle, Oliver; Koch, Philipp; Haass, Christian; Caflisch, Amedeo; Rajendran, Lawrence (2016). Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein. Cell Reports, 14(9):2127-2141.

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Fleischmann, Thea; Jirkof, Paulin; Henke, Julia; Arras, Margarete; Cesarovic, Nikola (2016). Injection anaesthesia with fentanyl-midazolam-medetomidine in adult female mice: importance of antagonization and perioperative care. Laboratory Animals, 50(4):264-274.

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Ghazanfari, Samaneh; Driessen-Mol, Anita; Hoerstrup, Simon P; Baaijens, Frank P T; Bouten, Carlijn V C (2016). Collagen Matrix Remodeling in Stented Pulmonary Arteries after Transapical Heart Valve Replacement. Cells, Tissues, Organs, 201(3):159-169.

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Książek, Agnieszka A. Hemodynamic assessment of a murine heterotopic biventricularly loaded cardiac transplant in vivo model. 2016, University of Zurich, Vetsuisse Faculty.

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Grinschgl, Sonja. Regulation of NMDA receptor subunit composition and synaptic alterations by the APP intracellular domain (AICD) in hippocampal neurons. 2016, University of Zurich, Faculty of Science.

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Hyman, Bradley T; Growdon, John H; Albers, Mark W; Buckner, Randy L; Chhatwal, Jasmeer; Gomez-Isla, Maria Teresa; Haass, Christian; Hudry, Eloise; Jack, Clifford R; Johnson, Keith A; Khachaturian, Zaven S; Kim, Doo Yeon; Martin, Joseph B; Nitsch, Roger M; Rosen, Bruce R; Selkoe, Dennis J; Sperling, Reisa A; St George-Hyslop, Peter; Tanzi, Rudolph E; Yap, Liang; Young, Anne B; Phelps, Creighton H; McCaffrey, Patricia G (2015). Massachusetts Alzheimer's Disease Research Center: Progress and challenges. Alzheimer's & Dementia, 11(10):1241-1245.

Jelcic, Ivan; Combaluzier, Benoit; Jelcic, Ilijas; Faigle, Wolfgang; Senn, Luzia; Reinhart, Brenda J; Ströh, Luisa; Nitsch, Roger M; Stehle, Thilo; Sospedra, Mireia; Grimm, Jan; Martin, Roland (2015). Broadly neutralizing human monoclonal JC polyomavirus VP1-specific antibodies as candidate therapeutics for progressive multifocal leukoencephalopathy. Science Translational Medicine, 7(306):306ra150.

Andreasson, Ulf; Perret-Liaudet, Armand; van Waalwijk van Doorn, Linda J C; Blennow, Kaj; Chiasserini, Davide; Engelborghs, Sebastiaan; Fladby, Tormod; Genc, Sermin; Kruse, Niels; Kuiperij, H Bea; Kulic, Luka; Lewczuk, Piotr; Mollenhauer, Brit; Mroczko, Barbara; Parnetti, Lucilla; Vanmechelen, Eugeen; Verbeek, Marcel M; Winblad, Bengt; Zetterberg, Henrik; Koel-Simmelink, Marleen; Teunissen, Charlotte E (2015). A Practical Guide to Immunoassay Method Validation. Frontiers in Neurology:6:179.

Lovis, Christian; Blaser, Jürg (2015). Biomedical informatics in Switzerland: need for action. Swiss Medical Weekly, 145:w14173.

Savaskan, E (2015). Schlafstörungen bei Demenzkranken. Zeitschrift für Gerontologie und Geriatrie, 48(4):312-317.

Spescha, R D; Klohs, J; Semerano, A; Giacalone, G; Derungs, R S; Reiner, M F; Rodriguez Gutierrez, D; Mendez-Carmona, N; Glanzmann, M; Savarese, G; Kränkel, N; Akhmedov, A; Keller, S; Mocharla, P; Kaufmann, M R; Wenger, R H; Vogel, J; Kulic, L; Nitsch, R M; Beer, J H; Peruzzotti-Jametti, L; Sessa, Maria; Lüscher, Thomas F; Camici, G G (2015). Post-ischaemic silencing of p66Shc reduces ischaemia/reperfusion brain injury and its expression correlates to clinical outcome in stroke. European Heart Journal, 36(25):1590-1600.

Welt, Tobias; Kulic, Luka; Hoey, Sarah E; McAfoose, Jordan; Späni, Claudia; Chadha, Antonella Santuccione; Fisher, Abraham; Nitsch, Roger M (2015). Acute effects of muscarinic M1 receptor modulation on AβPP metabolism and amyloid-β levels in vivo: a microdialysis study. Journal of Alzheimer's Disease, 46(4):971-982.

Savaskan, Egemen (2015). Behaviorale und psychologische Symptome der Demenz (BPSD): Was tun? Therapeutische Umschau. Revue thérapeutique, 72(4):255-260.

Unschuld, Paul G (2015). Möglichkeiten moderner Bildgebungstechnologien im Rahmen der Frühdiagnostik von Alzheimererkrankung. Therapeutische Umschau. Revue thérapeutique, 72(4):261-269.

Husmann, K; Arlt, M J E; Jirkof, P; Arras, M; Born, W; Fuchs, B (2015). Primary tumour growth in an orthotopic osteosarcoma mouse model is not influenced by analgesic treatment with buprenorphine and meloxicam. Laboratory Animals, 49(4):284-293.

Gietl, Anton F; Warnock, Geoffrey; Riese, Florian; Kälin, Andrea M; Saake, Antje; Gruber, Esmeralda; Leh, Sandra E; Unschuld, Paul G; Kuhn, Felix P; Burger, Cyrill; Mu, Linjing; Seifert, Burkhardt; Nitsch, Roger M; Schibli, Roger; Ametamey, Simon M; Buck, Alfred; Hock, Christoph (2015). Regional cerebral blood flow estimated by early PiB uptake is reduced in mild cognitive impairment and associated with age in an amyloid-dependent manner. Neurobiology of Aging, 36(4):1619-1628.

Thakur, Garima. A-Synuclein-Unconventional Secretion and Homeostatic Regulation. 2015, University of Zurich, Faculty of Science.

Kressig, R W; Démonet, J F; Georgescu, D; Ibach, B; Jung, H H; Pihan, H; Monsch, A U; Mosimann, U O; Savaskan, Egemen (2015). Anwendung des hoch dosierten transdermalen Rivastigmin-Pflasters bei der Behandlung der Alzheimer-Erkrankung. Der Informierte Arzt, 4:20-22.

Jirkof, P; Tourvieille, A; Cinelli, P; Arras, M (2015). Buprenorphine for pain relief in mice: Repeated injections vs sustained-release depot formulation. Laboratory Animals, 49(3):177-187.

Birnbaum, J H; Bali, J; Rajendran, L; Nitsch, R M; Tackenberg, C (2015). Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss. Cell Death and Disease, 6:e1791.

Unternaehrer, Eva; Meyer, Andrea Hans; Burkhardt, Susan C A; Dempster, Emma; Staehli, Simon; Theill, Nathan; Lieb, Roselind; Meinlschmidt, Gunther (2015). Childhood maternal care is associated with DNA methylation of the genes for brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) in peripheral blood cells in adult men and women. Stress, 18(4):451-461.

Forstmeier, Simon; Maercker, Andreas; Savaskan, Egemen; Roth, Tanja (2015). Cognitive behavioural treatment for mild Alzheimer's patients and their caregivers (CBTAC): study protocol for a randomized controlled trial. Trials, 16(1):526.

Unschuld, Paul G. Cognitive deficits as a reflection of brain change in neuro-psychiatric disorder. 2015, University of Zurich, Faculty of Medicine.

Pagani, Francesca; Paolicelli, Rosa C; Murana, Emanuele; Cortese, Barbara; Di Angelantonio, Silvia; Zurolo, Emanuele; Guiducci, Eva; Ferreira, Tiago A; Garofalo, Stefano; Catalano, Myriam; D'Alessandro, Giuseppina; Porzia, Alessandra; Peruzzi, Giovanna; Mainiero, Fabrizio; Limatola, Cristina; Gross, Cornelius T; Ragozzino, Davide (2015). Defective microglial development in the hippocampus of Cx3cr1 deficient mice. Frontiers in Cellular Neuroscience:9:111.

Eggenberger, Patrick; Schumacher, Vera; Angst, Marius; Theill, Nathan; de Bruin, Eling D (2015). Does multicomponent physical exercise with simultaneous cognitive training boost cognitive performance in older adults? A 6-month randomized controlled trial with a 1-year follow-up. Clinical Interventions in Aging, 10:1335-1349.

Jirkof, Paulin (2015). Effects of experimental housing conditions on recovery of laboratory mice. Lab animal, 44(2):65-70.

Kälin, Andrea M. Evaluation of a cognitive and a morphometric marker for the early detection of Alzheimer's disease. 2015, University of Zurich, Faculty of Arts.

Riese, Florian (2015). Geriatric Psychiatry. In: Wright, James D. International Encyclopedia of the Social & Behavioral Sciences (Second Edition). Amsterdam: Elsevier, 104-108.

Riese, F; Guloksuz, S; Roventa, C; Fair, J D; Haravuori, H; Rolko, T; Flynn, D; Giacco, D; Banjac, V; Jovanovic, N; Bayat, N; Palumbo, C; Rusaka, M; Kilic, O; Augėnaitė, J; Nawka, A; Zenger, M; Kekin, I; Wuyts, P; Barrett, E; Bausch-Becker, N; Mikaliūnas, J; Del Valle, E; Feffer, K; Lomax, G A; Marques, J G; Jauhar, S (2015). Pharmaceutical industry interactions of psychiatric trainees from 20 European countries. European Psychiatry, 30(2):284-290.

Gietl, Anton F (2015). Positronen-Emissions-Tomographie in der Demenzdiagnostik. Schweizer Archiv für Neurologie und Psychiatrie, 166(4):126-134.

Riese, Florian; Gietl, Anton; Zölch, Niklaus; Henning, Anke; O'Gorman, Ruth; Kälin, Andrea M; Leh, Sandra E; Buck, Alfred; Warnock, Geoffrey; Edden, Richard A E; Luechinger, Roger; Hock, Christoph; Kollias, Spyros; Michels, Lars (2015). Posterior cingulate GABA and glutamate+glutamine are reduced in amnestic mild cognitive impairment and are unrelated to amyloid deposition and APOE genotype. Neurobiology of Aging, 36(1):53-59.

Gersbacher, Manuel T. Proteasomal Degradation of the APP Intracellular Domain (AICD) and Regulation of its Nuclear Signaling. 2015, University of Zurich, Faculty of Science.

Späni, Claudia. Role of the adaptive immune system in the pathogenesis of Alzheimer's disease. 2015, University of Zurich, Faculty of Science.

Gietl, Anton F; Unschuld, Paul Gerson (2015). Screening und Prävention kognitiver Störungen bei älteren Menschen. Swiss Medical Forum, 15(43):982-986.

Wirth, Fabian. Therapeutic Approaches in Animal Moedels of Human Protein Misfolding Diseases. 2015, University of Zurich, Faculty of Science.

Karlen, Sascha; Oertle, Marc; Weiler, Stefan; Schneemann, Markus; Eschmann, Emmanuel; Kullak-Ublick, Gerd-Achim; Blaser, Juerg (2015). Too frequent low-dose methotrexate prescriptions: multicentre quality control and quality assurance with pre- and post-analysis. Swiss Medical Weekly, 145:w14218.

Böker, Heinz; Hartwich, Peter; Northoff, Georg (2015). Vorwort. In: Böker, Heinz; Hartwich, Peter; Northoff, Georg. Neuropsychodynamische Psychiatrie. Heidelberg: Springer, V-VII.


Beeler, Patrick Emanuel; Bates, David Westfall; Hug, Balthasar Luzius (2014). Clinical decision support systems. Swiss Medical Weekly, 144:w14073.

Weisskopf, Michael; Bucklar, Guido; Blaser, Jürg (2014). Tools in a clinical information system supporting clinical trials at a Swiss University Hospital. Clinical Trials, 11(6):673-680.

Rajendran, Lawrence; Bali, Jitin; Barr, Maureen M; Court, Felipe A; Krämer-Albers, Eva-Maria; Picou, Frederic; Raposo, Graça; van der Vos, Kristan E; van Niel, Guillaume; Wang, Juan; Breakefield, Xandra O (2014). Emerging roles of extracellular vesicles in the nervous system. Journal of Neuroscience, 34(46):15482-15489.

Grandjean, Joanes; Schroeter, Aileen; He, Pan; Tanadini, Matteo; Keist, Ruth; Krstic, Dimitrije; Konietzko, Uwe; Klohs, Jan; Nitsch, Roger M; Rudin, Markus (2014). Early alterations in functional connectivity and white matter structure in a transgenic mouse model of cerebral amyloidosis. Journal of Neuroscience, 34(41):13780-13789.

Laurig, Matthias. Quantification of subcortical gray-matter vascularization using 7 Tesla time-of flight angiography. 2014, University of Zurich, Faculty of Medicine.

Vassar, Robert; Kuhn, Peer-Hendrik; Haass, Christian; Kennedy, Matthew E; Rajendran, Lawrence; Wong, Philip C; Lichtenthaler, Stefan F (2014). Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects. Journal of Neurochemistry, 130(1):4-28.

Driessen-Mol, Anita; Emmert, Maximilian Y; Dijkman, Petra E; Frese, Laura; Sanders, Bart; Weber, Benedikt; Cesarovic, Nikola; Sidler, Michèle; Leenders, Jori; Jenni, Rolf; Grünenfelder, Jürg; Falk, Volkmar; Baaijens, Frank P T; Hoerstrup, Simon P (2014). Transcatheter implantation of homologous “off-the-shelf” tissue engineered heart valves with self-repair capacity: long term functionality and rapid in vivo remodeling in sheep. Journal of the American College of Cardiology, 63(13):1320-1329.

Ross, Christopher A; Aylward, Elizabeth H; Wild, Edward J; Langbehn, Douglas R; Long, Jeffrey D; Warner, John H; Scahill, Rachael I; Leavitt, Blair R; Stout, Julie C; Paulsen, Jane S; Reilmann, Ralf; Unschuld, Paul G; Wexler, Alice; Margolis, Russell L; Tabrizi, Sarah J (2014). Huntington disease: natural history, biomarkers and prospects for therapeutics. Nature Reviews. Neurology, 10(4):204-216.

Savaskan, Egemen; Bopp-Kistler, Irene; Buerge, Markus; Fischlin, Regina; Georgescu, Dan; Giardini, Umberto; Hatzinger, Martin; Hemmeter, Ulrich; Justiniano, Isabella; Kressig, Reto W; Monsch, Andreas; Mosimann, Urs P; Mueri, Renè; Munk, Anna; Popp, Julius; Schmid, Ruth; Wollmer, Marc A (2014). Empfehlungen zur Diagnostik und Therapie der behavioralen und psychologischen Symptome der Demenz (BPSD). Praxis, 103(3):135-48.

Hanenberg, Michael; McAfoose, Jordan; Kulic, Luka; Welt, Tobias; Wirth, Fabian; Parizek, Petra; Strobel, Lisa; Cattepoel, Susann; Späni, Claudia; Derungs, Rebecca; Maier, Marcel; Plückthun, Andreas; Nitsch, Roger M (2014). Amyloid-β peptide-specific DARPins as a novel class of potential therapeutics for Alzheimer disease. Journal of Biological Chemistry, 289(39):27080-27089.

Jirkof, Paulin Denise. Animal welfare in biomedical research - Behavioural alterations as pain indicators in laboratory mice. 2014, University of Zurich, Faculty of Science.

Jirkof, Paulin (2014). Burrowing and nest building behavior as indicators of well-being in mice. Journal of Neuroscience Methods, 234:139-146.

Ben Halima, Saoussen. Cell Biology of Non-Amyloid Substrates of β-Secretase in Alzheimer's Disease. 2014, University of Zurich, Faculty of Science.

Steininger, Stefanie C; Liu, Xinyang; Gietl, Anton; et al (2014). Cortical Amyloid Beta in Cognitively Normal Elderly Adults is Associated with Decreased Network Efficiency within the Cerebro-Cerebellar System. Frontiers in Aging Neuroscience:6:52.

Gietl, Anton; Savaskan, Egemen (2014). Differenzialdiagnose der Demenz. Psych up2date, 8(06):349-364.

Hua, Jun; Unschuld, Paul G; Margolis, Russell L; van Zijl, Peter C M; Ross, Christopher A (2014). Elevated arteriolar cerebral blood volume in prodromal Huntington's disease. Movement Disorders, 29:396-401.

Schuler, B; Rieger, G; Gubser, M; Arras, M; Gianella, M; Vogel, O; Jirkof, P; Cesarovic, N; Klohs, J; Jakob, P; Brock, M; Gorr, T A; Baum, O; Hoppeler, H; Samillan-Soto, V; Gassmann, M; Fischer, J A; Born, W; Vogel, J (2014). Endogenous α-calcitonin-gene-related peptide promotes exercise-induced, physiological heart hypertrophy in mice. Acta Physiologica, 211(1):107-121.

Beeler, P E; Eschmann, E; Schumacher, A; Studt, J-D; Amann-Vesti, B; Blaser, J (2014). Impact of electronic reminders on venous thromboprophylaxis after admissions and transfers. Journal of the American Medical Informatics Association (JAMIA), (21):e297-e303.

Cesarovic, Nikola; Arras, Margarete; Jirkof, Paulin (2014). Impact of inhalation anaesthesia, surgery and analgesic treatment on home cage behaviour in laboratory mice. Applied Animal Behaviour Science, 157:137-145.

Kälin, Andrea M; Pflüger, Marlon; Gietl, Anton F; Riese, Florian; Jäncke, Lutz; Nitsch, Roger M; Hock, Christoph (2014). Intraindividual variability across cognitive tasks as a potential marker for prodromal Alzheimer's disease. Frontiers in Aging Neuroscience:6:147.

Schilling, Thomas M; Ferreira de Sá, Diana S; Westerhausen, René; Strelzyk, Florian; Larra, Mauro F; Hallschmid, Manfred; Savaskan, Egemen; Oitzl, Melly S; Busch, Hans-Peter; Naumann, Ewald; Schächinger, Hartmut (2014). Intranasal insulin increases regional cerebral blood flow in the insular cortex in men independently of cortisol manipulation. Human Brain Mapping, 35(5):1944-1956.

Meier, Irene B; Gu, Yian; Guzaman, Vanessa A; Wiegman, Anne F; Schupf, Nicole; Manly, Jennifer J; Luchsinger, José A; Viswanathan, Anand; Martinez-Ramirez, Sergi; Greenberg, Steven M; Mayeux, Richard; Brickman, Adam M (2014). Lobar microbleeds are associated with a decline in executive functioning in older adults. Cerebrovascular Diseases, 38(5):377-383.

Eschmann, Emmanuel; Beeler, Patrick E; Kaplan, Vladimir; Schneemann, Markus; Zünd, Gregor; Blaser, Jürg (2014). Patient- and physician-related risk factors for hyperkalaemia in potassium-increasing drug-drug interactions. European Journal of Clinical Pharmacology, 70(2):215-223.

Saller, Reinhard; Kasper, Siegfried; Dimpfel, Wilfried; Savaskan, Egemen; Pfister, Thomas; Rostock, Matthias; Witt, Claudia; Thuile, Christian; Das, Oliver; Unger, Matthias (2014). Phytotherapie in der Geriatrie und Gerontologie. Forschende Komplementärmedizin, 21(Suppl 1):2-18.

Unschuld, Paul G; Buchholz, Alison S; Varvaris, Mark; van Zijl, Peter C M; Ross, Christopher A; Pekar, James J; Hock, Christoph; Sweeney, John A; Tamminga, Carol A; Keshavan, Matcheri S; Pearlson, Godfrey D; Thaker, Gunvant K; Schretlen, David J (2014). Prefrontal brain network connectivity indicates degree of both schizophrenia risk and cognitive dysfunction. Schizophrenia Bulletin, 40(3):653-664.

Domingues, Sara C; Konietzko, Uwe; Henriques, Ana Gabriela; Rebelo, Sandra; Fardilha, Margarida; Nishitani, Hideo; Nitsch, Roger M; da Cruz E Silva, Edgar F; da Cruz E Silva, Odete A B (2014). RanBP9 modulates AICD localization and transcriptional activity via direct interaction with Tip60. Journal of Alzheimer's Disease, 42(4):1415-1433.

Keskitalo, Salla; Farkas, Melinda; Hanenberg, Michael; Szodorai, Anita; Kulic, Luka; Semmler, Alexander; Weller, Michael; Nitsch, Roger M; Linnebank, Michael (2014). Reciprocal modulation of Aβ42 aggregation by copper and homocysteine. Frontiers in Aging Neuroscience:6:237.

Schreiner, Simon J; Liu, Xinyang; Gietl, Anton F; Wyss, Michael; Steininger, Stefanie C; Gruber, Esmeralda; Treyer, Valerie; Meier, Irene B; Kälin, Andrea M; Leh, Sandra E; Buck, Alfred; Nitsch, Roger M; Pruessmann, Klaas P; Hock, Christoph; Unschuld, Paul G (2014). Regional Fluid-Attenuated Inversion Recovery (FLAIR) at 7 Tesla correlates with amyloid beta in hippocampus and brainstem of cognitively normal elderly subjects. Frontiers in Aging Neuroscience:6:240.

Stämpfli, Simon F; Camici, Giovanni G; Keller, Stephan; Rozenberg, Izabela; Arras, Margarete; Schuler, Beat; Gassmann, Max; Garcia, Irene; Lüscher, Thomas F; Tanner, Felix C (2014). Restraint stress enhances arterial thrombosis in vivo - Role of the sympathetic nervous system. Stress, 17(1):126-132.

Tackenberg, Christian; Ghori, Adnan; Brandt, Roland (2014). Thin, Stubby or Mushroom: Spine Pathology in Alzheimer's Disease. In: Lahiri, D K. Advances in Alzheimer's Research. Sharjah, U.A.E.: Bentham Science Publishers Ltd., 375-394.


Jirkof, P; Leucht, K; Cesarovic, N; Caj, M; Nicholls, F; Rogler, G; Arras, M; Hausmann, M (2013). Burrowing is a sensitive behavioural assay for monitoring general wellbeing during dextran sulfate sodium colitis in laboratory mice. Laboratory Animals, 47(4):274-283.

Jirkof, Paulin; Cesarovic, Nikola; Rettich, Andreas; Arras, Margarete (2013). Housing of female mice in a new environment and its influence on post-surgical behaviour and recovery. Applied Animal Behaviour Science, 148(3-4):209-217.

Bali, Jitin. System Biology of beta-Amyloid Production: Implications in Alzheimer's disease. 2013, University of Zurich, Faculty of Medicine.

Strobel, Lisa. Targeted Drug Delivery Against Beta-aAyloidosis in an Alzheimer's Disease Mouse Model by Using Focused Ultrasound Technology. 2013, University of Zurich, Faculty of Science.

Kaufmann, M R; Barth, S; Konietzko, U; Wu, Bei; Egger, Sascha; Kunze, Reiner; Marti, Hugo H; Hick, Meike; Müller, Ulrike; Camenisch, G; Wenger, R H (2013). Dysregulation of Hypoxia-Inducible Factor by Presenilin/ Gamma-Secretase Loss-of-Function Mutations. Journal of Neuroscience, 33(5):1915-1926.

Buggia-Prévot, Virginie; Fernandez, Celia G; Udayar, Vinod; Vetrivel, Kulandaivelu S; Elie, Aureliane; Roseman, Jelita; Sasse, Verena A; Lefkow, Margaret; Meckler, Xavier; Bhattacharyya, Sohinee; George, Manju; Kar, Satyabrata; Bindokas, Vytautas P; Parent, Angèle T; Rajendran, Lawrence; Band, Hamid; Vassar, Robert; Thinakaran, Gopal (2013). A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer's disease Aβ production. Cell Reports, 5(6):1552-1563.

Udayar, Vinod; Buggia-Prévot, Virginie; Guerreiro, Rita L; Siegel, Gabriele; Rambabu, Naresh; Soohoo, Amanda L; Ponnusamy, Moorthi; Siegenthaler, Barbara; Bali, Jitin; Simons, Mikael; Ries, Jonas; Puthenveedu, Manojkumar A; Hardy, John; Thinakaran, Gopal; Rajendran, Lawrence (2013). A paired RNAi and RabGAP overexpression screen identifies Rab11 as a regulator of β-Amyloid production. Cell Reports, 5(6):1536-1551.

Santuccione, A C; Merlini, M; Shetty, A; Tackenberg, C; Bali, J; Ferretti, M T; McAfoose, J; Kulic, L; Bernreuther, C; Welt, T; Grimm, J; Glatzel, M; Rajendran, L; Hock, C; Nitsch, R M (2013). Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice. Molecular Psychiatry, 18(3):358-368.

Jirkof, Paulin; Fleischmann, Thea; Cesarovic, Nikola; Rettich, Andreas; Vogel, Johannes; Arras, Margarete (2013). Assessment of postsurgical distress and pain in laboratory mice by nest complexity scoring. Laboratory Animals, 47(3):153-161.

Bengtsson, S K; Johansson, M; Bäckström, T; Nitsch, R M; Wang, M (2013). Brief but chronic increase in allopregnanolone cause accelerated AD pathology eifferently in two mouse models. Current Alzheimer research, 10(1):38-47.

Emmert, Maximilian Y; Salzberg, Sacha P; Seifert, Burkhardt; Scherman, Jacques; Plass, Andre; Starck, Christoph T; Theusinger, Oliver; Hoerstrup, Simon P; Grünenfelder, Jürg; Jacobs, Stephan; Falk, Volkmar (2013). Clampless off-pump surgery reduces stroke in patients with left main disease. International journal of cardiology, 167(5):2097-2101.

Spescha, R D; Shi, Y; Wegener, S; Keller, S; Weber, B; Wyss, M M; Lauinger, N; Tabatabai, G; Paneni, F; Cosentino, F; Hock, C; Weller, M; Nitsch, R M; Lüscher, T F; Camici, G G (2013). Deletion of the ageing gene p66Shc reduces early stroke size following ischaemia/reperfusion brain injury. European Heart Journal, 34(2):96-103.

Eschmann, Emmanuel; Beeler, Patrick E; Zünd, Gregor; Blaser, Jürg (2013). Evaluation of alerts for potassium-increasing drug-drug-interactions. In: Lehmann, Christoph Ulrich; Ammenwerth, Elske; Nøhr, Christian. MEDINFO 2013. Amsterdam, Berlin, Tokyo, Washington DC: I O S Press, 1056.

Baur, Volker; Brühl, Annette Beatrix; Herwig, Uwe; Eberle, Tanja; Rufer, Michael; Delsignore, Aba; Jäncke, Lutz; Hänggi, Jürgen (2013). Evidence of frontotemporal structural hypoconnectivity in social anxiety disorder: a quantitative fiber tractography study. Human Brain Mapping, 34(2):437-446.

Qin, Yuan-Yuan; Hsu, Johnny T; Yoshida, Shoko; Faria, Andreia V; Oishi, Kumiko; Unschuld, Paul G; Redgrave, Graham W; Ying, Sarah H; Ross, Christopher A; van Zijl, Peter C M; Hillis, Argye E; Albert, Marilyn S; Lyketsos, Constantine G; Miller, Michael I; Mori, Susumu; Oishi, Kenichi (2013). Gross feature recognition of anatomical images based on atlas grid (GAIA): incorporating the local discrepancy between an atlas and a target image to capture the features of anatomic brain MRI. NeuroImage: Clinical, 3:202-211.

Farkas, M; Keskitalo, S; Smith, D E C; Bain, N; Semmler, A; Ineichen, B; Smulders, Y; Blom, H; Kulic, L; Linnebank, M (2013). Hyperhomocysteinemia in Alzheimer's disease: The hen and the egg? Journal of Alzheimer's disease : JAD, 33(4):1097-1104.

Crucet, M; Wuest, Sophia J A; Spielmann, P; Luescher, T F; Wenger, R H; Matter, C M (2013). Hypoxia enhances lipid uptake in macrophages: Role of the scavenger receptors Lox1, SRA, and CD36. Atherosclerosis, 229(1):110-117.

Klohs, Jan; Politano, Igna Wojtyna; Deistung, Andreas; Grandjean, Joanes; Drewek, Anna; Dominietto, Marco; Keist, Ruth; Schweser, Ferdinand; Reichenbach, Jürgen R; Nitsch, Roger M; Knuesel, Irene; Rudin, Markus (2013). Longitudinal assessment of amyloid pathology in transgenic ArcAβ mice using multi-parametric magnetic resonance imaging. PLoS ONE, 8(6):e66097.

Tackenberg, C; Grinschgl, S; Trutzel, A; Santuccione, A C; Frey, M C; Konietzko, U; Grimm, J; Brandt, R; Nitsch, R M (2013). NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss. Cell Death and Disease, 4:e608.

Unschuld, Paul G; Liu, Xinyang; Shanahan, Megan; Margolis, Russell L; Bassett, Susan S; Brandt, Jason; Schretlen, David J; Redgrave, Graham W; Hua, Jun; Hock, Christoph; Reading, Sarah A; van Zijl, Peter C M; Pekar, James J; Ross, Christopher A (2013). Prefrontal executive function associated coupling relates to Huntington's disease stage. Cortex, 49(10):2661-2673.

Laurig, Mathias; Liu, Xinyang; Wyss, Michael; Gietl, Anton; Jellestad, Lena; Nitsch, Roger M; Prüssmann, Klaas; Hock, Christoph; Unschuld, Paul G (2013). Quantification of subcortical gray-matter vascularization using 7 Tesla time-of-flight angiography. Brain and Behavior, 3(5):515-518.

Kloiber, Stefan; Ripke, Stephan; Kohli, Martin A; Reppermund, Simone; Salyakina, Daria; Uher, Rudolf; McGuffin, Peter; Perlis, Roy H; Hamilton, Steven P; Pütz, Benno; Hennings, Johannes; Brückl, Tanja; Klengel, Torsten; Bettecken, Thomas; Ising, Marcus; Uhr, Manfred; Dose, Tatjana; Unschuld, Paul G; Zihl, Josef; Binder, Elisabeth; Müller-Myhsok, Bertram; Holsboer, Florian; Lucae, Susanne (2013). Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels. European Neuropsychopharmacology, 23(7):653-662.

Ries, Jonas; Udayar, Vinod; Soragni, Alice; Hornemann, Simone; Nilsson, K Peter R; Riek, Roland; Hock, Christoph; Ewers, Helge; Aguzzi, Adriano A; Rajendran, Lawrence (2013). Superresolution imaging of amyloid fibrils with binding-activated probes. ACS Chemical Neuroscience, 4(7):1057-1061.

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