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Achermann, P; Finelli, L A; Borbely, A A (2001). Unihemispheric enhancement of delta power in human frontal sleep EEG by prolonged wakefulness. Brain Research, 913(2):220-223.

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EEG power spectra exhibit site-specific and state-related differences in specific frequency bands. In the present study we investigated the effect of total sleep deprivation on sleep EEG topography. Eight healthy, young, right-handed subjects were recorded during baseline sleep and recovery sleep after sleep deprivation. Forty hours of sleep deprivation affected power spectra in all derivations. However, hemispheric asymmetries were observed in the delta range. Sleep deprivation enhanced the anterior predominance of delta activity in the left hemisphere but not in the right one. This effect may reflect a functional asymmetry between the dominant and non-dominant hemisphere. The results provide further evidence for the presence of both global and local aspects of sleep regulation.

Item Type:Journal Article, refereed
Communities & Collections:04 Faculty of Medicine > Institute of Pharmacology and Toxicology
DDC:570 Life sciences; biology
610 Medicine & health
Date:21 September 2001
Deposited On:11 Feb 2008 12:18
Last Modified:27 Nov 2013 22:45
Publisher DOI:10.1016/S0006-8993(01)02796-2
PubMed ID:11549390
Citations:Web of Science®. Times Cited: 41
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Scopus®. Citation Count: 45

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