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07 Faculty of Science > Department of Biochemistry"

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Spiliotopoulos, Dimitrios; Wamhoff, Eike-Christian; Lolli, Graziano; Rademacher, Christoph; Caflisch, Amedeo (2017). Discovery of BAZ2A bromodomain ligands. European journal of medicinal chemistry, 139:564-572.

Hansen, Simon; Kiefer, Jonathan D; Madhurantakam, Chaithanya; Mittl, Peer R E; Plückthun, Andreas (2017). Structures of designed armadillo repeat proteins binding to peptides fused to globular domains. Protein Science, 26(10):1942-1952.

Peón, Antonio; Robles, Adrián; Blanco, Beatriz; Convertino, Marino; Thompson, Paul; Hawkins, Alastair R; Caflisch, Amedeo; González-Bello, Concepción (2017). Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study. ChemMedChem, 12(18):1512-1524.

Niewoehner, Ole; Jinek, Martin (2017). Specialized weaponry: how a type III-A CRISPR-cas system excels at combating phages. Cell Host & Microbe, 22(3):258-259.

Wu, Yufan; Batyuk, Alexander; Honegger, Annemarie; Brandl, Fabian; Mittl, Peer R E; Plückthun, Andreas (2017). Rigidly connected multispecific artificial binders with adjustable geometries. Scientific Reports, 7(1):11217.

Jost, Christian; Stüber, Jakob C; Honegger, Annemarie; Wu, Yufan; Batyuk, Alexander; Plückthun, Andreas (2017). Rigidity of the extracellular part of HER2: evidence from engineering subdomain interfaces and shared-helix DARPin-DARPin fusions. Protein Science, 26(9):1796-1806.

Niewoehner, Ole; Garcia-Doval, Carmela; Rostøl, Jakob T; Berk, Christian; Schwede, Frank; Bigler, Laurent; Hall, Jonathan; Marraffini, Luciano A; Jinek, Martin (2017). Type III CRISPR-Cas systems produce cyclic oligoadenylate second messengers. Nature, 548(7669):543-548.

Schenck, Stephan; Kunz, Laura; Sahlender, Daniela; Pardon, Els; Geertsma, Eric R; Savtchouk, Iaroslav; Suzuki, Toshiharu; Neldner, Yvonne; Štefanić, Saša; Steyaert, Jan; Volterra, Andrea; Dutzler, Raimund (2017). Generation and characterization of Anti-VGLUT nanobodies acting as inhibitors of transport. Biochemistry, 56(30):3962-3971.

Plitzko, Jürgen M; Schuler, Benjamin; Selenko, Philipp (2017). Structural biology outside the box-inside the cell. Current Opinion in Structural Biology, 46:110-121.

Palermo, Giulia; Miao, Yinglong; Walker, Ross C; Jinek, Martin; McCammon, J Andrew (2017). CRISPR-Cas9 conformational activation as elucidated from enhanced molecular simulations. Proceedings of the National Academy of Sciences of the United States of America, 114(28):7260-7265.

Afroz, Tariq; Hock, Eva-Maria; Ernst, Patrick; Foglieni, Chiara; Jambeau, Melanie; Gilhespy, Larissa A B; Laferriere, Florent; Maniecka, Zuzanna; Plückthun, Andreas; Mittl, Peer; Paganetti, Paolo; Allain, Frédéric H T; Polymenidou, Magdalini (2017). Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation. Nature Communications, 8:45.

Turgay, Y; Medalia, O (2017). The structure of lamin filaments in somatic cells as revealed by cryo-electron tomography. Nucleus:Epub ahead of print.

Parren, Paul W H I; Carter, Paul J; Plückthun, Andreas (2017). Changes to International Nonproprietary Names for antibody therapeutics 2017 and beyond: of mice, men and more. mAbs, 9(6):898-906.

Zijlstra, Niels; Dingfelder, Fabian; Wunderlich, Bengt; Zosel, Franziska; Benke, Stephan; Nettels, Daniel; Schuler, Benjamin (2017). Rapid microfluidic dilution for single-molecule spectroscopy of low-affinity biomolecular complexes. Angewandte Chemie Internationale Edition, 56(25):7126-7129.

Skegro, Darko; Stutz, Cian; Ollier, Romain; Svensson, Emelie; Wassmann, Paul; Bourquin, Florence; Monney, Thierry; Gn, Sunitha; Blein, Stanislas (2017). Immunoglobulin domain interface exchange as a platform technology for the generation of Fc heterodimers and bispecific antibodies. Journal of Biological Chemistry, 292(23):9745-9759.

Samatanga, Brighton; Cléry, Antoine; Barraud, Pierre; Allain, Frédéric H-T; Jelesarov, Ilian (2017). Comparative analyses of the thermodynamic RNA binding signatures of different types of RNA recognition motifs. Nucleic Acids Research, 45(10):6037-6050.

Spiliotopoulos, Dimitrios; Zhu, Jian; Wamhoff, Eike-Christian; Deerain, Nicholas; Marchand, Jean-Rémy; Aretz, Jonas; Rademacher, Christoph; Caflisch, Amedeo (2017). Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorganic & Medicinal Chemistry Letters, 27(11):2472-2478.

Paulino, Cristina; Neldner, Yvonne; Lam, Andy Km; Kalienkova, Valeria; Brunner, Janine Denise; Schenck, Stephan; Dutzler, Raimund (2017). Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A. eLife, 6:26232.

Vašák, Milan; Meloni, Gabriele (2017). Mammalian metallothionein-3: new functional and structural insights. International Journal of Molecular Sciences, 18(6):1117.

Dingfelder, Fabian; Wunderlich, Bengt; Benke, Stephan; Zosel, Franziska; Zijlstra, Niels; Nettels, Daniel; Schuler, Benjamin (2017). Rapid microfluidic double-jump mixing device for single-molecule spectroscopy. Journal of the American Chemical Society, 139(17):6062-6065.

Ruggeri, Francesca; Zosel, Franziska; Mutter, Natalie; Różycka, Mirosława; Wojtas, Magdalena; Ożyhar, Andrzej; Schuler, Benjamin; Krishnan, Madhavi (2017). Single-molecule electrometry. Nature Nanotechnology, 12(5):488-495.

Swarts, Daan C; van der Oost, John; Jinek, Martin (2017). Structural basis for guide RNA processing and seed-dependent DNA targeting by CRISPR-Cas12a. Molecular Cell, 66(2):221-233.e4.

Ranganathan, Anirudh; Heine, Philipp; Rudling, Axel; Plückthun, Andreas; Kummer, Lutz; Carlsson, Jens (2017). Ligand discovery for a peptide-binding GPCR by Structure-based screening of fragment- and lead-like chemical libraries. ACS Chemical Biology, 12(3):735-745.

Benke, Stephan; Nettels, Daniel; Hofmann, Hagen; Schuler, Benjamin (2017). Quantifying kinetics from time series of single-molecule Förster resonance energy transfer efficiency histograms. Nanotechnology, 28(11):114002.

Malka-Gibor, Eti; Kornreich, Micha; Laser-Azogui, Adi; Doron, Ofer; Zingerman-Koladko, Irena; Harapin, Jan; Medalia, Ohad; Beck, Roy (2017). Phosphorylation-Induced Mechanical Regulation of Intrinsically Disordered Neurofilament Proteins. Biophysical Journal, 112(5):892-900.

Turgay, Yagmur; Eibauer, Matthias; Goldman, Anne E; Shimi, Takeshi; Khayat, Maayan; Ben-Harush, Kfir; Dubrovsky-Gaupp, Anna; Sapra, K Tanuj; Goldman, Robert D; Medalia, Ohad (2017). The molecular architecture of lamins in somatic cells. Nature, 543(7644):261-264.

Soranno, Andrea; Holla, Andrea; Dingfelder, Fabian; Nettels, Daniel; Makarov, Dmitrii E; Schuler, Benjamin (2017). Integrated view of internal friction in unfolded proteins from single-molecule FRET, contact quenching, theory, and simulations. Proceedings of the National Academy of Sciences of the United States of America, 114(10):E1833-E1839.

Anders, Ulrike; Schaefer, Jonas V; Hibti, Fatima-Ezzahra; Frydman, Chiraz; Suckau, Detlev; Plückthun, Andreas; Zenobi, Renato (2017). SPRi-MALDI MS: characterization and identification of a kinase from cell lysate by specific interaction with different designed ankyrin repeat proteins. Analytical and Bioanalytical Chemistry, 409(7):1827-1836.

Ghayor, Chafik; Gjoksi, Bebeka; Dong, Jing; Siegenthaler, Barbara; Caflisch, Amedeo; Weber, Franz E (2017). N,N Dimethylacetamide a drug excipient that acts as bromodomain ligand for osteoporosis treatment. Scientific Reports, 7:42108.

Ehrnstorfer, Ines A; Manatschal, Cristina; Arnold, Fabian M; Laederach, Juerg; Dutzler, Raimund (2017). Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family. Nature Communications, 8:14033.

Syafrizayanti; Lueong, Smiths S; Di, Cuixia; Schaefer, Jonas V; Plückthun, Andreas; Hoheisel, Jörg D (2017). Personalised proteome analysis by means of protein microarrays made from individual patient samples. Scientific Reports, 7:39756.

Ernst, Patrick; Plückthun, Andreas (2017). Advances in the design and engineering of peptide-binding repeat proteins. Biological Chemistry, 398(1):23-29.

Nasr, Mahmoud L; Baptista, Diego; Strauss, Mike; Sun, Zhen-Yu J; Grigoriu, Simina; Huser, Sonja; Plückthun, Andreas; Hagn, Franz; Walz, Thomas; Hogle, James M; Wagner, Gerhard (2017). Covalently circularized nanodiscs for studying membrane proteins and viral entry. Nature Methods, 14(1):49-52.

Obexer, Richard; Godina, Alexei; Garrabou, Xavier; Mittl, Peer R E; Baker, David; Griffiths, Andrew D; Hilvert, Donald (2017). Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase. Nature Chemistry, 9(1):50-56.

Verdurmen, Wouter P R; Mazlami, Marigona; Plückthun, Andreas (2017). A Biotin Ligase-Based Assay for the Quantification of the Cytosolic Delivery of Therapeutic Proteins. Methods in Molecular Biology, 1575:223-236.

Marino, Jacopo; Holzhüter, Katharina; Kuhn, Benedikt; Geertsma, Eric R (2017). Efficient Screening and Optimization of Membrane Protein Production in Escherichia coli. Methods in Enzymology, 594:139-164.

Kramer, Lovro; Renko, Miha; Završnik, Janja; Turk, Dušan; Seeger, Markus A; Vasiljeva, Olga; Grütter, Markus G; Turk, Vito; Turk, Boris (2017). Non-invasive in vivo imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin. Theranostics, 7(11):2806-2821.

Huber, Sylwia; Casagrande, Fabio; Hug, Melanie N; Wang, Lisha; Heine, Philipp; Kummer, Lutz; Plückthun, Andreas; Hennig, Michael (2017). SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands. PLoS ONE, 12(5):e0175842.

Lim, Novandy. Structural and functional characterization of TMEM16 family members. 2016, University of Zurich, Faculty of Science.

Schiller, Christian B; Braciak, Todd A; Fenn, Nadja C; Seidel, Ursula J E; Roskopf, Claudia C; Wildenhain, Sarah; Honegger, Annemarie; Schubert, Ingo A; Schele, Alexandra; Lämmermann, Kerstin; Fey, Georg H; Jacob, Uwe; Lang, Peter; Hopfner, Karl-Peter; Oduncu, Fuat S (2016). CD19-specific triplebody SPM-1 engages NK and γδ T cells for rapid and efficient lysis of malignant B-lymphoid cells. OncoTarget, 7(50):83392-83408.

Zosel, Franziska. Dynamics and interactions of intrinsically disordered proteins studied with single-molecule spectroscopy. 2016, University of Zurich, Faculty of Science.

Reimão-Pinto, Madalena M; Manzenreither, Raphael A; Burkard, Thomas R; Sledz, Pawel; Jinek, Martin; Mechtler, Karl; Ameres, Stefan L (2016). Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila. EMBO Journal Online, 35(22):2417-2434.

Marchand, Jean-Rémy; Lolli, Graziano; Caflisch, Amedeo (2016). Derivatives of 3-Amino-2-methylpyridine as BAZ2B Bromodomain Ligands: In Silico Discovery and in Crystallo Validation. Journal of Medicinal Chemistry, 59(21):9919-9927.

Börmel, Mandy. Structural analysis of zipping during dorsal closure in drosophila melanogaster embryogenesis. 2016, University of Zurich, Faculty of Science.

Borgia, Alessandro; Zheng, Wenwei; Buholzer, Karin; Borgia, Madeleine B; Schüler, Anja; Hofmann, Hagen; Soranno, Andrea; Nettels, Daniel; Gast, Klaus; Grishaev, Alexander; Best, Robert B; Schuler, Benjamin (2016). Consistent view of polypeptide chain expansion in chemical denaturants from multiple experimental methods. Journal of the American Chemical Society, 138(36):11714-11726.

Zheng, Wenwei; Borgia, Alessandro; Buholzer, Karin; Grishaev, Alexander; Schuler, Benjamin; Best, Robert B (2016). Probing the Action of Chemical Denaturant on an Intrinsically Disordered Protein by Simulation and Experiment. Journal of the American Chemical Society, 138(36):11702-11713.

Aznauryan, Mikayel; Delgado, Leonildo; Soranno, Andrea; Nettels, Daniel; Huang, Jie-Rong; Labhardt, Alexander M; Grzesiek, Stephan; Schuler, Benjamin (2016). Comprehensive structural and dynamical view of an unfolded protein from the combination of single-molecule FRET, NMR, and SAXS. Proceedings of the National Academy of Sciences of the United States of America, 113(37):E5389-E5398.

Green, Anthony P; Hayashi, Takahiro; Mittl, Peer R E; Hilvert, Donald (2016). A chemically programmed proximal ligand enhances the catalytic properties of a heme enzyme. Journal of the American Chemical Society, 138(35):11344-11352.

Sorrentino, Simona; Studt, Jan-Dirk; Horev, Melanie Bokstad; Medalia, Ohad; Sapra, K Tanuj (2016). Toward correlating structure and mechanics of platelets. Cell Adhesion & Migration, 10(5):568-575.

Engeler, Sibylle. Structural and functional analysis of prokaryotic pentameric ligand-gated ion channels. 2016, University of Zurich, Faculty of Science.

Lindsay, Helen; Burger, Alexa; Biyong, Berthin; Felker, Anastasia; Hess, Christopher; Zaugg, Jonas; Chiavacci, Elena; Anders, Carolin; Jinek, Martin; Mosimann, Christian; Robinson, Mark D (2016). CrispRVariants charts the mutation spectrum of genome engineering experiments. Nature Biotechnology, 34(7):701-702.

Schuler, Benjamin; Soranno, Andrea; Hofmann, Hagen; Nettels, Daniel (2016). Single-molecule FRET spectroscopy and the polymer physics of unfolded and intrinsically disordered proteins. Annual review of biophysics, 45:207-231.

Goricanec, David; Stehle, Ralf; Egloff, Pascal; Grigoriu, Simina; Plückthun, Andreas; Wagner, Gerhard; Hagn, Franz (2016). Conformational dynamics of a G-protein α subunit is tightly regulated by nucleotide binding. Proceedings of the National Academy of Sciences of the United States of America, 113(26):E3629-E3638.

Brunner, Janine D; Schenck, Stephan; Dutzler, Raimund (2016). Structural basis for phospholipid scrambling in the TMEM16 family. Current Opinion in Structural Biology, 39:61-70.

Zhu, Jian; Caflisch, Amedeo (2016). Twenty crystal structures of bromodomain and PHD finger containing protein 1 (BRPF1)/ligand complexes reveal conserved binding motifs and rare interactions. Journal of Medicinal Chemistry, 59(11):5555-5561.

Zingerman-Koladko, Irena; Khayat, Maayan; Harapin, Jan; Shoseyov, Oded; Gruenbaum, Yosef; Salman, Ahmad; Medalia, Ohad; Ben-Harush, Kfir (2016). The assembly of C. elegans lamins into macroscopic fibers. Journal of the Mechanical Behavior of Biomedical Materials, 63:35-43.

Burger, Alexa; Lindsay, Helen; Felker, Anastasia; Hess, Christopher; Anders, Carolin; Chiavacci, Elena; Zaugg, Jonas; Weber, Lukas M; Catena, Raul; Jinek, Martin; Robinson, Mark D; Mosimann, Christian (2016). Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes. Development, 143(11):2025-2037.

Bender, Ruben R; Muth, Anke; Schneider, Irene C; Friedel, Thorsten; Hartmann, Jessica; Plückthun, Andreas; Maisner, Andrea; Buchholz, Christian J (2016). Receptor-targeted nipah virus glycoproteins improve cell-type selective gene delivery and reveal a preference for membrane-proximal cell attachment. PLoS Pathogens, 12(6):e1005641.

Geertsma, Eric R; Chang, Yung-Ning; Shaik, Farooque R; Neldner, Yvonne; Pardon, Els; Steyaert, Jan; Dutzler, Raimund (2016). Corrigendum: Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family. Nature Structural & Molecular Biology, 23(5):462.

Spalinger, Marianne R; Kasper, Stephanie; Gottier, Claudia; Lang, Silvia; Atrott, Kirstin; Vavricka, Stephan R; Scharl, Sylvie; Gutte, Petrus M; Grütter, Markus G; Beer, Hans-Dietmar; Contassot, Emmanuel; Chan, Andrew C; Dai, Xuezhi; Rawlings, David J; Mair, Florian; Becher, Burkhard; Falk, Werner; Fried, Michael; Rogler, Gerhard; Scharl, Michael (2016). NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22. Journal of Clinical Investigation, 126(5):1783-1800.

Zuela, Noam; Zwerger, Monika; Levin, Tal; Medalia, Ohad; Gruenbaum, Yosef (2016). Impaired mechanical response of an EDMD mutation leads to motility phenotypes that are repaired by loss of prenylation. Journal of Cell Science, 129(9):1781-1791.

Batyuk, Alexander; Wu, Yufan; Honegger, Annemarie; Heberling, Matthew M; Plückthun, Andreas (2016). DARPin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography. Journal of Molecular Biology, 428(8):1574-1588.

Schütz, Marco; Batyuk, Alexander; Klenk, Christoph; Kummer, Lutz; de Picciotto, Seymour; Gülbakan, Basri; Wu, Yufan; Newby, Gregory A; Zosel, Franziska; Schöppe, Jendrik; Sedlák, Erik; Mittl, Peer R E; Zenobi, Renato; Wittrup, K Dane; Plückthun, Andreas (2016). Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools. Journal of Molecular Biology, 428(6):1272-1289.

Lolli, Graziano; Caflisch, Amedeo (2016). High-Throughput Fragment Docking into the BAZ2B Bromodomain: Efficient in Silico Screening for X-Ray Crystallography. ACS Chemical Biology, 11(3):800-807.

Anders, Carolin; Bargsten, Katja; Jinek, Martin (2016). Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9. Molecular Cell, 61(6):895-902.

Hansen, Simon; Tremmel, Dirk; Madhurantakam, Chaithanya; Reichen, Christian; Mittl, Peer R E; Plückthun, Andreas (2016). Structure and Energetic Contributions of a Designed Modular Peptide-Binding Protein with Picomolar Affinity. Journal of the American Chemical Society, 138(10):3526-3532.

Roderer, Daniel; Benke, Stephan; Schuler, Benjamin; Glockshuber, Rudi (2016). Soluble oligomers of the pore-forming toxin cytolysin a from escherichia coli are off-pathway products of pore assembly. Journal of Biological Chemistry, 291(11):5652-5663.

Xu, Min; Caflisch, Amedeo; Hamm, Peter (2016). Protein Structural Memory Influences Ligand Binding Mode(s) and Unbinding Rates. Journal of Chemical Theory and Computation, 12(3):1393-1399.

Ben Halima, Saoussen; Mishra, Sabyashachi; Raja, K Muruga Poopathi; Willem, Michael; Baici, Antonio; Simons, Kai; Brüstle, Oliver; Koch, Philipp; Haass, Christian; Caflisch, Amedeo; Rajendran, Lawrence (2016). Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein. Cell Reports, 14(9):2127-2141.

Olieric, Vincent; Weinert, Tobias; Finke, Aaron D; Anders, Carolin; Li, Dianfan; Olieric, Natacha; Borca, Camelia N; Steinmetz, Michel O; Caffrey, Martin; Jinek, Martin; Wang, Meitian (2016). Data-collection strategy for challenging native SAD phasing. Acta Crystallographica. Section D: Structural Biology, 72(Pt 3):421-429.

Zwerger, Monika; Eibauer, Matthias; Medalia, Ohad (2016). Insights into the gate of the nuclear pore complex. Nucleus, 7(1):1-7.

Bertozzi, Carlo; Zimmermann, Iwan; Engeler, Sibylle; Hilf, Ricarda J C; Dutzler, Raimund (2016). Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels. PLoS Biology, 14(3):e1002393.

Niewoehner, Ole; Jinek, Martin (2016). Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6. RNA, 22(3):318-329.

Tamir, Adi; Sorrentino, Simona; Motahedeh, Sarah; Shai, Ela; Dubrovsky, Anna; Dahan, Idit; Eibauer, Matthias; Studt, Jan-Dirk; Sapra, K Tanuj; Varon, David; Medalia, Ohad (2016). The macromolecular architecture of platelet-derived microparticles. Journal of Structural Biology, 193(3):181-187.

Dubey, Gyanendra P; Malli Mohan, Ganesh Babu; Dubrovsky, Anna; Amen, Triana; Tsipshtein, Shai; Rouvinski, Alex; Rosenberg, Alex; Kaganovich, Daniel; Sherman, Eilon; Medalia, Ohad; Ben-Yehuda, Sigal (2016). Architecture and Characteristics of Bacterial Nanotubes. Developmental Cell, 36(4):453-61.

Irobalieva, Rossitza N; Martins, Bruno; Medalia, Ohad (2016). Cellular structural biology as revealed by cryo-electron tomography. Journal of Cell Science, 129(3):469-476.

Jones, Tim D; Carter, Paul J; Plückthun, Andreas; et al (2016). The INNs and outs of antibody nonproprietary names. mAbs, 8(1):1-9.

Reichen, Christian; Madhurantakam, Chaithanya; Hansen, Simon; Grütter, Markus G; Plückthun, Andreas; Mittl, Peer R E (2016). Structures of designed armadillo-repeat proteins show propagation of inter-repeat interface effects. Acta Crystallographica. Section D: Structural Biology, 72(Pt 1):168-175.

Roos, Martina; Pradère, Ugo; Ngondo, Richard P; Behera, Alok; Allegrini, Sara; Civenni, Gianluca; Zagalak, Julian A; Marchand, Jean-Rémy; Menzi, Mirjam; Towbin, Harry; Scheuermann, Jörg; Neri, Dario; Caflisch, Amedeo; Catapano, Carlo V; Ciaudo, Constance; Hall, Jonathan (2016). A Small-Molecule Inhibitor of Lin28. ACS Chemical Biology, 11(10):2773-2781.

Klenk, Christoph; Ehrenmann, Janosch; Schütz, Marco; Plückthun, Andreas (2016). A generic selection system for improved expression and thermostability of G protein-coupled receptors by directed evolution. Scientific Reports, 6:21294.

Reichen, Christian; Hansen, Simon; Forzani, Cristina; Honegger, Annemarie; Fleishman, Sarel J; Zhou, Ting; Parmeggiani, Fabio; Ernst, Patrick; Madhurantakam, Chaithanya; Ewald, Christina; Mittl, Peer R E; Zerbe, Oliver; Baker, David; Caflisch, Amedeo; Plückthun, Andreas (2016). Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition. Journal of Molecular Biology, 428(22):4467-4489.

Müller, Christian S; Knehans, Tim; Davydov, Dmitri R; Bounds, Patricia L; von Mandach, Ursula; Halpert, James R; Caflisch, Amedeo; Koppenol, Willem H (2016). Correction to concurrent cooperativity and substrate inhibition in the epoxidation of carbamazepine by cytochrome P450 3A4 active site mutants inspired by molecular dynamics simulations. Biochemistry, 55(39):5647.

Spalinger, Marianne R; Kasper, Stephanie; Gottier, Claudia; Lang, Silvia; Atrott, Kirstin; Vavricka, Stephan R; Scharl, Sylvie; Raselli, Tina; Frey-Wagner, Isabelle; Gutte, Petrus M; Grütter, Markus G; Beer, Hans-Dietmar; Contassot, Emmanuel; Chan, Andrew C; Dai, Xuezhi; Rawlings, David J; Mair, Florian; Becher, Burkhard; Falk, Werner; Fried, Michael; Rogler, Gerhard; Scharl, Michael (2016). Corrigendum - NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22. Journal of Clinical Investigation, 126(11):4388.

Meyer, Peter A; Socias, Stephanie; Key, Jason; Ransey, Elizabeth; Tjon, Emily C; Buschiazzo, Alejandro; Lei, Ming; Botka, Chris; Withrow, James; Neau, David; Rajashankar, Kanagalaghatta; Anderson, Karen S; Baxter, Richard H; Blacklow, Stephen C; Boggon, Titus J; Bonvin, Alexandre M J J; Borek, Dominika; Brett, Tom J; Caflisch, Amedeo; Chang, Chung-I; Chazin, Walter J; Corbett, Kevin D; Cosgrove, Michael S; Crosson, Sean; Dhe-Paganon, Sirano; Di Cera, Enrico; Drennan, Catherine L; Eck, Michael J; Eichman, Brandt F; Fan, Qing R; Ferré-D'Amaré, Adrian R; Christopher Fromme, J; Garcia, K Christopher; Gaudet, Rachelle; Gong, Peng; Harrison, Stephen C; Heldwein, Ekaterina E; Jia, Zongchao; Keenan, Robert J; Kruse, Andrew C; Kvansakul, Marc; McLellan, Jason S; Modis, Yorgo; Nam, Yunsun; Otwinowski, Zbyszek; Pai, Emil F; Pereira, Pedro José Barbosa; Petosa, Carlo; Raman, C S; Rapoport, Tom A; Roll-Mecak, Antonina; Rosen, Michael K; Rudenko, Gabby; Schlessinger, Joseph; Schwartz, Thomas U; Shamoo, Yousif; Sondermann, Holger; Tao, Yizhi J; Tolia, Niraj H; Tsodikov, Oleg V; Westover, Kenneth D; Wu, Hao; Foster, Ian; Fraser, James S; Maia, Filipe R N C; Gonen, Tamir; Kirchhausen, Tom; Diederichs, Kay; Crosas, Mercè; Sliz, Piotr (2016). Data publication with the structural biology data grid supports live analysis. Nature Communications, 7:10882.

Ahmad, Shoeb; Pecqueur, Ludovic; Dreier, Birgit; Hamdane, Djemel; Aumont-Nicaise, Magali; Plückthun, Andreas; Knossow, Marcel; Gigant, Benoît (2016). Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin. Scientific Reports, 6:28922.

Schütz, Marco; Schöppe, Jendrik; Sedlák, Erik; Hillenbrand, Matthias; Nagy-Davidescu, Gabriela; Ehrenmann, Janosch; Klenk, Christoph; Egloff, Pascal; Kummer, Lutz; Plückthun, Andreas (2016). Directed evolution of G protein-coupled receptors in yeast for higher functional production in eukaryotic expression hosts. Scientific Reports, 6:21508.

Arnon, Zohar A; Vitalis, Andreas; Levin, Aviad; Michaels, Thomas C T; Caflisch, Amedeo; Knowles, Tuomas P J; Adler-Abramovich, Lihi; Gazit, Ehud (2016). Dynamic microfluidic control of supramolecular peptide self-assembly. Nature Communications, 7:13190.

Hanauer, Jan Rh; Gottschlich, Lisa; Riehl, Dennis; Rusch, Tillmann; Koch, Vivian; Friedrich, Katrin; Hutzler, Stefan; Prüfer, Steffen; Friedel, Thorsten; Hanschmann, Kay-Martin; Münch, Robert C; Jost, Christian; Plückthun, Andreas; Cichutek, Klaus; Buchholz, Christian J; Mühlebach, Michael D (2016). Enhanced lysis by bispecific oncolytic measles viruses simultaneously using HER2/neu or EpCAM as target receptors. Molecular Therapy - Oncolytics, 3:16003.

Benke, Stephan; Roderer, Daniel; Wunderlich, Bengt; Nettels, Daniel; Glockshuber, Rudi; Schuler, Benjamin (2016). Erratum: The assembly dynamics of the cytolytic pore toxin ClyA. Nature Communications, 7:10650.

Unzue, Andrea; Xu, Ming; Dong, Jing; Wiedmer, Lars; Spiliotopoulos, Dimitrios; Caflisch, Amedeo; Nevado, Cristina (2016). Fragment-based design of selective nanomolar ligands of the crebbp bromodomain. Journal of Medicinal Chemistry, 59(4):1350-1356.

Spiliotopoulos, Dimitrios; Caflisch, Amedeo (2016). Fragment-based in silico screening of bromodomain ligands. Drug Discovery Today: Technologies, 19:81-90.

Bode, Heiko; Bourquin, Florence; Suriyanarayanan, Saranya; Wei, Yu; Alecu, Irina; Othman, Alaa; von Eckardstein, Arnold; Hornemann, Thorsten (2016). HSAN1 mutations in serine palmitoyltransferase reveal a close structure-function-phenotype relationship. Human Molecular Genetics, 25(5):853-865.

Lim, Novandy K; Lam, Andy K M; Dutzler, Raimund (2016). Independent activation of ion conduction pores in the double-barreled calcium-activated chloride channel TMEM16A. Journal of General Physiology, 148(5):375-392.

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Morger, Damian. Pattern recognition of the HIV-1 capsid by the innate immune receptor TRIM5. 2014, University of Zurich, Faculty of Science.

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Eidam, O. Structural and functional insights into the assemblyof type 1 pili from uropathogenic E.coli. 2008, University of Zurich, Department of Biochemistry, Faculty of Medicine.

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Pahlich, S; Zakaryan, R P; Gehring, H (2006). Protein arginine methylation: Cellular functions and methods of analysis. Biochimica et Biophysica Acta, 1764(12):1890-1903.

Konecna, A; Frischknecht, R; Kinter, J; Ludwig, A; Steuble, M; Meskenaite, V; Indermühle, M; Engel, M; Cen, Chuan; Mateos, J M; Streit, P; Sonderegger, P (2006). Calsyntenin-1 docks vesicular cargo to kinesin-1. Molecular Biology of the Cell, 17(8):3651-3663.

Galliciotti, G; Sonderegger, P (2006). Neuroserpin. Frontiers in Bioscience, 11:33-45.

Meyer, S; Dutzler, R (2006). Crystal structure of the cytoplasmic domain of the chloride channel ClC-0. Structure, 14(2):299-307.

Accardi, A; Lobet, S; Williams, C; Miller, C J; Dutzler, R (2006). Synergism between halide binding and proton transport in a CLC-type exchanger. Journal of Molecular Biology, 362(4):691-699.

Dutzler, R (2006). The ClC family of chloride channels and transporters. Current Opinion in Structural Biology, 16(4):439-46.

Lebeurrier, N; Liot, G; Lopez-Atalaya, J P; Orset, C; Fernandez-Monreal, M; Sonderegger, P; Ali, C; Vivien, D (2005). The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo. Molecular and Cellular Neuroscience, 30(4):552-558.

Pahlich, S; Bschir, K; Chiavi, C; Belyanskaya, L L; Gehring, H (2005). Different methylation characteristics of protein arginine methyltransferase 1 and 3 toward the Ewing Sarcoma protein and a peptide. Proteins, 61(1):164-175.

Schrimpf, S P; Meskenaite, V; Brunner, E; Rutishauser, D; Walther, P; Eng, J K; Aebersold, R; Sonderegger, P (2005). Proteomic analysis of synaptosomes using isotope-coded affinity tags and mass spectrometry. Proteomics, 5(10):2531-2541.

Röthlisberger, D; Honegger, A; Plückthun, A (2005). Domain interactions in the Fab fragment: a comparative evaluation of the single-chain Fv and Fab format engineered with variable domains of different stability. Journal of Molecular Biology, 347(4):773-789.

Ott, D; Neldner, Y; Cèbe, R; Dodevski, I; Plückthun, A (2005). Engineering and functional immobilization of opioid receptors. Protein Engineering Design and Selection : PEDS, 18(3):153-160.

Fernandez, F J; Vega, M C; Lehmann, F; Sandmeier, E; Gehring, H; Christen, P; Wilmanns, M (2004). Structural studies of the catalytic reaction pathway of a hyperthermophilic histidinol-phosphate aminotransferase. Journal of Biological Chemistry, 279(20):21478-21488.

Navarro-Yubero, C; Cuadrado, A; Sonderegger, P; Muñoz, A (2004). Neuroserpin is post-transcriptionally regulated by thyroid hormone. Molecular Brain Research, 123(1-2):56-65.

Röthlisberger, D; Pos, K M; Plückthun, A (2004). An antibody library for stabilizing and crystallizing membrane proteins - selecting binders to the citrate carrier CitS. FEBS Letters, 564(3):340-348.

Ott, D; Frischknecht, R; Plückthun, A (2004). Construction and characterization of a kappa opioid receptor devoid of all free cysteines. Protein Engineering Design and Selection : PEDS, 17(1):37-48.

Dutzler, R (2004). Structural basis for ion conduction and gating in ClC chloride channels. FEBS Letters, 564(3):229-33.

Dutzler, R (2004). The structural basis of ClC chloride channel function. Trends in Neurosciences, 27(6):315-20.

Gygi, D J; Zumstein, P; Grossenbacher, D; Altwegg, L; Lüscher, T F; Gehring, H (2003). Human connective tissue growth factor expressed in Escherichia coli is a non-mitogenic inhibitor of apoptosis. Biochemical and Biophysical Research Communications (BBRC), 311(3):685-690.

Molinari, F; Meskanaite, Virginia; Munnich, A; Sonderegger, P; Colleaux, L (2003). Extracellular proteases and their inhibitors in genetic diseases of the central nervous system. Human Molecular Genetics, 12(S2):R195-R200.

Madani, Rime; Kozlov, S V; Akhmedov, A; Cinelli, P; Kinter, J; Lipp, H P; Sonderegger, P; Wolfer, D P (2003). Impaired explorative behavior and neophobia in genetically modified mice lacking or overexpressing the extracellular serine protease inhibitor neuroserpin. Molecular and Cellular Neuroscience, 23(3):473-494.

Wannier-Morino, P; Rager, G; Sonderegger, P; Grabs, D (2003). Expression of neuroserpin in the visual cortex of the mouse during the developmental critical period. European Journal of Neuroscience, 17(9):1853-1860.

Belyanskaya, L L; Delattre, O; Gehring, H (2003). Expression and subcellular localization of Ewing sarcoma (EWS) protein is affected by the methylation process. Experimental Cell Research, 288(2):374-381.

Dutzler, R; Campbell, E B; MacKinnon, R (2003). Gating the selectivity filter in ClC chloride channels. Science, 300(5616):108-12.

Molinari, F; Rio, M; Meskenaite, V; Encha-Razavi, F; Augé, J; Bacq, D; Briault, S; Vekemans, M; Munnich, A; Attié-Bitach, T; Sonderegger, P; Colleaux, L (2002). Truncating neurotrypsin mutation in autosomal recessive nonsyndromic mental retardation. Science, 298(5599):1779-1781.

Hintsch, G; Zurlinden, A; Meskenaite, V; Steuble, M; Fink-Widmer, K; Kinter, J; Sonderegger, P (2002). The calsyntenins--a family of postsynaptic membrane proteins with distinct neuronal expression patterns. Molecular and Cellular Neuroscience, 21(3):393-409.

Minder, D; Böni, J; Schüpbach, J; Gehring, H (2002). Immunophilins and HIV-1 infection. Archives of Virology, 147(8):1531-1542.

Cuadrado, A; Navarro-Yubero, C; Furneaux, H; Kinter, J; Sonderegger, P; Muñoz, A (2002). HuD binds to three AU-rich sequences in the 3'-UTR of neuroserpin mRNA and promotes the accumulation of neuroserpin mRNA and protein. Nucleic Acids Research, 30(10):2202-2211.

Kunz, B; Lierheimer, R; Rader, C; Spirig, M; Ziegler, U; Sonderegger, P (2002). Axonin-1/TAG-1 mediates cell-cell adhesion by a cis-assisted trans-interaction. Journal of Biological Chemistry, 277(6):4551-4557.

Dutzler, R; Schirmer, T; Karplus, M; Fischer, S (2002). Translocation mechanism of long sugar chains across the maltoporin membrane channel. Structure, 10(9):1273-84.

Dutzler, R; Campbell, E B; Cadene, M; Chait, B T; MacKinnon, R (2002). X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity. Nature, 415(6869):287-94.

Cinelli, P; Madani, R; Tsuzuki, N; Vallet, P; Arras, M; Zhao, C N; Osterwalder, T; Rülicke, T; Sonderegger, P (2001). Neuroserpin, a neuroprotective factor in focal ischemic stroke. Molecular and Cellular Neuroscience, 18(5):443-457.

Wolfer, D P; Lang, R; Cinelli, P; Madani, R; Sonderegger, P (2001). Multiple roles of neurotrypsin in tissue morphogenesis and nervous system development suggested by the mRNA expression pattern. Molecular and Cellular Neuroscience, 18(4):407-433.

Alvarez-Dolado, M; Figueroa, A; Kozlov, S V; Sonderegger, P; Furley, A J; Muñoz, A (2001). Thyroid hormone regulates TAG-1 expression in the developing rat brain. European Journal of Neuroscience, 14(8):1209-1218.

Briand, C; Kozlov, S V; Sonderegger, P; Grütter, M G (2001). Crystal structure of neuroserpin: a neuronal serpin involved in a conformational disease. FEBS Letters, 505(1):18-22.

Bernard, A; Fitzli, D; Sonderegger, P; Delamarche, E; Michel, B; Bosshard, H R; Biebuyck, H (2001). Affinity capture of proteins from solution and their dissociation by contact printing. Nature Biotechnology, 19(9):866-869.

Plagge, A; Sendtner-Voelderndorff, L; Sirim, P; Freigang, J; Rader, C; Sonderegger, P; Brümmendorf, T (2001). The contactin-related protein FAR-2 defines purkinje cell clusters and labels subpopulations of climbing fibers in the developing cerebellum. Molecular and Cellular Neuroscience, 18(1):91-107.

Silverman, M A; Kaech, S; Jareb, M; Burack, M A; Vogt, L; Sonderegger, P; Banker, G (2001). Sorting and directed transport of membrane proteins during development of hippocampal neurons in culture. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 98(13):7051-7057.

Belyanskaya, L L; Gehrig, P M; Gehring, H (2001). Exposure on cell surface and extensive arginine methylation of ewing sarcoma (EWS) protein. Journal of Biological Chemistry, 276(22):18681-18687.

Sorribas, H; Braun, D; Leder, L; Sonderegger, P; Tiefenauer, L (2001). Adhesion proteins for a tight neuron-electrode contact. Journal of Neuroscience Methods, 104(2):133-141.

Vogt, L; Schrimpf, S P; Meskenaite, V; Frischknecht, R; Kinter, J; Leone, D P; Ziegler, U; Sonderegger, P (2001). Calsyntenin-1, a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain. Molecular and Cellular Neuroscience, 17(1):151-166.

Sonderegger, P; Kunz, S; Rader, C; Suter, D M; Stoeckli, E T (2001). Analysis of Cell-Cell Contact Mediated by Ig Superfamily Cell Adhesion Molecules. Current Protocols in Cell Biology:9.5.1-9.5.52.

Van Gelder, P; Dutzler, R; Dumas, F; Koebnik, R; Schirmer, T (2001). Sucrose transport through maltoporin mutants of Escherichia coli. Protein engineering, 14(11):943-8.

Alvarez-Dolado, M; Cuadrado, A; Navarro-Yubero, C; Sonderegger, P; Furley, A J; Bernal, J; Muñoz, A (2000). Regulation of the L1 cell adhesion molecule by thyroid hormone in the developing brain. Molecular and Cellular Neuroscience, 16(4):499-514.

Kasper, P; Christen, P; Gehring, H (2000). Empirical calculation of the relative free energies of peptide binding to the molecular chaperone DnaK. Proteins, 40(2):185-192.

Fitzli, D; Stoeckli, E T; Kunz, S; Siribour, K; Rader, C; Kunz, B; Kozlov, S V; Buchstaller, A; Lane, R P; Suter, D M; Dreyer, W J; Sonderegger, P (2000). A direct interaction of axonin-1 with NgCAM-related cell adhesion molecule (NrCAM) results in guidance, but not growth of commissural axons. Journal of Cell Biology, 149(4):951-968.

Freigang, J; Proba, K; Leder, L; Diederichs, K; Sonderegger, P; Welte, W (2000). The crystal structure of the ligand binding module of axonin-1/TAG-1 suggests a zipper mechanism for neural cell adhesion. Cell, 101(4):425-433.

Görlach, A; Camenisch, G; Kvietikova, I; Vogt, L; Wenger, R H; Gassmann, M (2000). Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions. Biochimica et Biophysica Acta, 1493(1-2):125-134.

Finckh, U; Müller-Thomsen, T; Mann, U; Eggers, C; Marksteiner, J; Meins, W; Binetti, G; Alberici, A; Sonderegger, P; Hock, C; Nitsch, R M; Gal, A (2000). High frequency of mutations in four different disease genes in early-onset dementia. Annals of the New York Academy of Sciences, 920:100-106.

Camuzat, A; Verpillat, P; Dubois, B; Penet, C; Agid, Y; Brice, A; Moreaud, O; Puel, M; Clerget-Darpoux, F; Kinter, J; Kozlov, S; Berger, P; Sonderegger, P; Raux, G; Campion, C; Hannequin, D; Febourg, T (2000). Mutations in the neuroserpin gene are rare in familial dementia. Annals of Neurology, 47(5):688.

Sorribas, H; Padeste, C; Mezzacasa, T; Tiefenauer, L; Leder, L; Fitzli, D; Sonderegger, P (1999). Neurite outgrowth on microstructured surfaces functionalized by a neural adhesion protein. Journal of Materials Science: Materials in Medicine, 10(12):787-791.

Berger, P; Kozlov, S V; Cinelli, P; Krüger, S R; Vogt, L; Sonderegger, P (1999). Neuronal depolarization enhances the transcription of the neuronal serine protease inhibitor neuroserpin. Molecular and Cellular Neuroscience, 14(6):455-467.

Graber, R; Kasper, P; Malashkevich, V N; Strop, P; Gehring, H; Jansonius, J N; Christen, P (1999). Conversion of aspartate aminotransferase into an L-aspartate beta-decarboxylase by a triple active-site mutation. Journal of Biological Chemistry, 274(44):31203-1325.

Davis, R L; Shrimpton, A E; Holohan, P D; Bradshaw, C; Feiglin, D; Collins, G H; Sonderegger, P; Kinter, J; Becker, L M; Lacbawan, F; Krasnewich, D; Muenke, M; Lawrence, D A; Yerby, M S; Shaw, C M; Gooptu, B; Elliott, P R; Finch, J T; Carrell, R W; Lomas, D A (1999). Familial dementia caused by polymerization of mutant neuroserpin. Nature, 401(6751):376-379.

Endrich, M M; Gehrig, P; Gehring, H (1999). Maturation-induced conformational changes of HIV-1 capsid protein and identification of two high affinity sites for cyclophilins in the C-terminal domain. Journal of Biological Chemistry, 274(9):5326-5332.

Mouratou, B; Kasper, P; Gehring, H; Christen, P (1999). Conversion of tyrosine phenol-lyase to dicarboxylic amino acid beta-lyase, an enzyme not found in nature. Journal of Biological Chemistry, 274(3):1320-1325.

Kozlov, S V; Riegel, M; Kinter, J; Hintsch, G; Cinelli, P; Schinzel, A; Sonderegger, P (1999). Assignment of the gene encoding the neuronal multidomain serine protease neurotrypsin (PRSS12) to human chromosome band 4q25-->q26 by in situ hybridization. Cytogenetic and Genome Research, 84(1-2):107-108.

Dutzler, R; Rummel, G; Albertí, S; Hernández-Allés, S; Phale, P; Rosenbusch, J; Benedí, V; Schirmer, T (1999). Crystal structure and functional characterization of OmpK36, the osmoporin of Klebsiella pneumoniae. Structure, 7(4):425-34.

Ringhofer, S; Kallen, J; Dutzler, R; Billich, A; Visser, A J; Scholz, D; Steinhauser, O; Schreiber, H; Auer, M; Kungl, A J (1999). X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910: agreement of time-resolved spectroscopy and molecular dynamics simulations. Journal of Molecular Biology, 286(4):1147-59.

Kunz, S; Spirig, M; Ginsburg, C; Buchstaller, A; Berger, P; Lanz, R; Rader, C; Vogt, L; Kunz, B; Sonderegger, P (1998). Neurite fasciculation mediated by complexes of axonin-1 and Ng cell adhesion molecule. Journal of Cell Biology, 143(6):1673-1690.

Berger, P; Kozlov, S V; Krueger, S R; Sonderegger, P (1998). Structure of the mouse gene for the serine protease inhibitor neuroserpin (PI12). Gene, 214(1-2):25-33.

Endrich, M M; Gehring, H (1998). The V3 loop of human immunodeficiency virus type-1 envelope protein is a high-affinity ligand for immunophilins present in human blood. FEBS Journal, 252(3):441-446.

Proba, K; Gschwend, T P; Sonderegger, P (1998). Cloning and sequencing of the cDNA encoding human neurotrypsin. Biochimica et Biophysica Acta, 1396(2):143-147.

Wolfer, D P; Giger, R J; Stagliar, M; Sonderegger, P; Lipp, H P (1998). Expression of the axon growth-related neural adhesion molecule TAG-1/axonin-1 in the adult mouse brain. Anatomy and Embryology, 197(3):177-185.

Osterwalder, T; Cinelli, P; Baici, A; Pennella, A; Krueger, S R; Schrimpf, S P; Meins, M; Sonderegger, P (1998). The axonally secreted serine proteinase inhibitor, neuroserpin, inhibits plasminogen activators and plasmin but not thrombin. Journal of Biological Chemistry, 273(4):2312-2321.

Sonderegger, P; Kunz, S; Rader, C; Buchstaller, A; Berger, P; Vogt, L; Kozlov, S V; Ziegler, U; Kunz, B; Fitzli, D; Stoeckli, E T (1998). Discrete clusters of axonin-1 and NgCAM at neuronal contact sites: facts and speculations on the regulation of axonal fasciculation. Progress in Brain Research, 117:93-104.

Krueger, S R; Ghisu, G P; Cinelli, P; Gschwend, T P; Osterwalder, T; Wolfer, D P; Sonderegger, P (1997). Expression of neuroserpin, an inhibitor of tissue plasminogen activator, in the developing and adult nervous system of the mouse. Journal of Neuroscience, 17(23):8984-8996.

Sonderegger, P (1997). Axonin-1 and NgCAM as "recognition" components of the pathway sensor apparatus of growth cones: a synopsis. Cell and Tissue Research, 290(2):429-439.

Schrimpf, S P; Bleiker, A J; Brecevic, L; Kozlov, S V; Berger, P; Osterwalder, T; Krueger, S R; Schinzel, A; Sonderegger, P (1997). Human neuroserpin (PI12): cDNA cloning and chromosomal localization to 3q26. Genomics, 40(1):55-62.

Stoeckli, E T; Sonderegger, P; Pollerberg, G E; Landmesser, L T (1997). Interference with axonin-1 and NrCAM interactions unmasks a floor-plate activity inhibitory for commissural axons. Neuron, 18(2):209-221.

Lierheimer, R; Kunz, B; Vogt, L; Savoca, R; Brodbeck, U; Sonderegger, P (1997). The neuronal cell-adhesion molecule axonin-1 is specifically released by an endogenous glycosylphosphatidylinositol-specific phospholipase. FEBS Journal, 243(1-2):502-510.

Giger, R J; Ziegler, U; Hermens, W T J M C; Kunz, B; Kunz, S; Sonderegger, P (1997). Adenovirus-mediated gene transfer in neurons: construction and characterization of a vector for heterologous expression of the axonal cell adhesion molecule axonin-1. Journal of Neuroscience Methods, 71(1):99-111.

Wang, Y F; Dutzler, R; Rizkallah, P J; Rosenbusch, J P; Schirmer, T (1997). Channel specificity: structural basis for sugar discrimination and differential flux rates in maltoporin. Journal of Molecular Biology, 272(1):56-63.

Denzinger, T; Przybylski, M; Savoca, R; Sonderegger, P (1997). Mass spectrometric characterisation of primary structure, sequence heterogeneity, and intramolecular disulfide loops of the cell adhesion protein axonin-1 from chicken. European Journal of Mass Spectrometry, 3(5):379-389.

Gschwend, T P; Krueger, S R; Kozlov, S V; Wolfer, D P; Sonderegger, P (1997). Neurotrypsin, a novel multidomain serine protease expressed in the nervous system. Molecular and Cellular Neuroscience, 9(3):207-219.

Buchstaller, A; Kunz, S; Berger, P; Kunz, B; Ziegler, U; Rader, C; Sonderegger, P (1996). Cell adhesion molecules NgCAM and axonin-1 form heterodimers in the neuronal membrane and cooperate in neurite outgrowth promotion. Journal of Cell Biology, 135(6 Pt 1):1593-1607.

Kunz, S; Ziegler, U; Kunz, B; Sonderegger, P (1996). Intracellular signaling is changed after clustering of the neural cell adhesion molecules axonin-1 and NgCAM during neurite fasciculation. Journal of Cell Biology, 135(1):253-267.

Kasper, P; Sterk, M; Christen, P; Gehring, H (1996). Molecular-dynamics simulation of domain movements in aspartate aminotransferase. FEBS Journal, 240(3):751-755.

Vogt, L; Giger, R J; Ziegler, U; Kunz, B; Buchstaller, A; Hermens, W T J M C; Kaplitt, M G; Rosenfeld, M R; Pfaff, D W; Verhaagen, J; Sonderegger, P (1996). Continuous renewal of the axonal pathway sensor apparatus by insertion of new sensor molecules into the growth cone membrane. Current Biology, 6(9):1153-1158.

Stoeckli, E T; Ziegler, U; Bleiker, A J; Groscurth, P; Sonderegger, P (1996). Clustering and functional cooperation of Ng-CAM and axonin-1 in the substratum-contact area of growth cones. Developmental Biology, 177(1):15-29.

Christen, P; Kasper, P; Gehring, H; Sterk, M (1996). Stereochemical constraint in the evolution of pyridoxal-5'-phosphate-dependent enzymes. A hypothesis. FEBS Letters, 389(1):12-14.

Osterwalder, T; Contartese, J; Stoeckli, E T; Kuhn, T B; Sonderegger, P (1996). Neuroserpin, an axonally secreted serine protease inhibitor. The EMBO Journal, 15(12):2944-2953.

Rader, C; Kunz, B; Lierheimer, R; Giger, R J; Berger, P; Tittmann, P; Gross, H; Sonderegger, P (1996). Implications for the domain arrangement of axonin-1 derived from the mapping of its NgCAM binding site. The EMBO Journal, 15(9):2056-2068.

Morino, P; Buchstaller, A; Giger, R J; Sonderegger, P; Rager, G (1996). Differential expression of the mRNAs of the axonal glycoproteins axonin-1 and NgCAM in the developing chick retina. Developmental Brain Research, 91(2):252-259.

Rager, G; Morino, P; Schnitzer, J; Sonderegger, P (1996). Expression of the axonal cell adhesion molecules axonin-1 and Ng-CAM during the development of the chick retinotectal system. Journal of Comparative Neurology, 365(4):594-609.

Endrich, M M; Grossenbacher, D; Geistlich, A; Gehring, H (1996). Apoptosis-induced concomitant release of cytosolic proteins and factors which prevent cell death. Biology of the Cell, 88(1-2):15-22.

Dutzler, R; Wang, Y F; Rizkallah, P; Rosenbusch, J P; Schirmer, T (1996). Crystal structures of various maltooligosaccharides bound to maltoporin reveal a specific sugar translocation pathway. Structure, 4(2):127-34.

Kozlov, S V; Giger, R J; Hasler, T; Korvatska, E; Schorderet, D F; Sonderegger, P (1995). The human TAX1 gene encoding the axon-associated cell adhesion molecule TAG-1/axonin-1: genomic structure and basic promoter. Genomics, 30(2):141-148.

Suter, D M; Pollerberg, G E; Buchstaller, A; Giger, R J; Dreyer, W J; Sonderegger, P (1995). Binding between the neural cell adhesion molecules axonin-1 and Nr-CAM/Bravo is involved in neuron-glia interaction. Journal of Cell Biology, 131(4):1067-1081.

Graber, R; Kasper, P; Malashkevich, V N; Sandmeier, E; Berger, P; Gehring, H; Jansonius, J N; Christen, P (1995). Changing the reaction specificity of a pyridoxal-5'-phosphate-dependent enzyme. FEBS Journal, 232(2):686-690.

Giger, R J; Vogt, L; Zuellig, R A; Rader, C; Henehan-Beatty, A; Wolfer, D P; Sonderegger, P (1995). The gene of chicken axonin-1. Complete structure and analysis of the promoter. FEBS Journal, 227(3):617-628.

Malashkevich, V N; Jäger, J; Ziak, M; Sauder, U; Gehring, H; Christen, P; Jansonius, J N (1995). Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue. Biochemistry, 34(2):405-414.

Savoca, R; Ziegler, U; Sonderegger, P (1995). Effects of L-serine on neurons in vitro. Journal of Neuroscience Methods, 61(1-2):159-167.

Bonaïti-Pellié, C; Poisson, N; Bechtel, Y; Bechtel, P (1992). Sensitivity of transmission probabilities to paternity exclusion in segregation analysis. Genetic Epidemiology, 9(1):67-71.

This list was generated on Fri Oct 20 22:06:57 2017 CEST.