Publication: Two-step regulation of centromere distribution by condensin II and the nuclear envelope proteins
Two-step regulation of centromere distribution by condensin II and the nuclear envelope proteins
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Sakamoto, T., Sakamoto, Y., Grob, S., Slane, D., Yamashita, T., Ito, N., Oko, Y., Sugiyama, T., Higaki, T., Hasezawa, S., Tanaka, M., Matsui, A., Seki, M., Suzuki, T., Grossniklaus, U., & Matsunaga, S. (2022). Two-step regulation of centromere distribution by condensin II and the nuclear envelope proteins. Nature Plants, 8(8), 940–953. https://doi.org/10.1038/s41477-022-01200-3
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The arrangement of centromeres within the nucleus differs among species and cell types. However, neither the mechanisms determining centromere distribution nor its biological significance are currently well understood. In this study, we demonstrate the importance of centromere distribution for the maintenance of genome integrity through the cytogenic and molecular analysis of mutants defective in centromere distribution. We propose a two-step regulatory mechanism that shapes the non-Rabl-like centromere distribution in Arabidopsis tha
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Sakamoto, T., Sakamoto, Y., Grob, S., Slane, D., Yamashita, T., Ito, N., Oko, Y., Sugiyama, T., Higaki, T., Hasezawa, S., Tanaka, M., Matsui, A., Seki, M., Suzuki, T., Grossniklaus, U., & Matsunaga, S. (2022). Two-step regulation of centromere distribution by condensin II and the nuclear envelope proteins. Nature Plants, 8(8), 940–953. https://doi.org/10.1038/s41477-022-01200-3