Publication: Helena’s Many Daughters: More Mitogenome Diversity behind the Most Common West Eurasian mtDNA Control Region Haplotype in an Extended Italian Population Sample
Helena’s Many Daughters: More Mitogenome Diversity behind the Most Common West Eurasian mtDNA Control Region Haplotype in an Extended Italian Population Sample
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Bodner, M., Amory, C., Olivieri, A., Gandini, F., Cardinali, I., Lancioni, H., Huber, G., Xavier, C., Pala, M., Fichera, A., Schnaller, L., Gysi, M., Sarno, S., Pettener, D., Luiselli, D., Richards, M. B., Semino, O., Achilli, A., Torroni, A., & Parson, W. (2022). Helena’s Many Daughters: More Mitogenome Diversity behind the Most Common West Eurasian mtDNA Control Region Haplotype in an Extended Italian Population Sample. International Journal of Molecular Sciences, 23(12), 6725. https://doi.org/10.3390/ijms23126725
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The high number of matching haplotypes of the most common mitochondrial (mt)DNA lineages are considered to be the greatest limitation for forensic applications. This study investigates the potential to solve this constraint by massively parallel sequencing a large number of mitogenomes that share the most common West Eurasian mtDNA control region (CR) haplotype motif (263G 315.1C 16519C). We augmented a pilot study on 29 to a total of 216 Italian mitogenomes that represents the largest set of the most common CR haplotype compiled from
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Bodner, M., Amory, C., Olivieri, A., Gandini, F., Cardinali, I., Lancioni, H., Huber, G., Xavier, C., Pala, M., Fichera, A., Schnaller, L., Gysi, M., Sarno, S., Pettener, D., Luiselli, D., Richards, M. B., Semino, O., Achilli, A., Torroni, A., & Parson, W. (2022). Helena’s Many Daughters: More Mitogenome Diversity behind the Most Common West Eurasian mtDNA Control Region Haplotype in an Extended Italian Population Sample. International Journal of Molecular Sciences, 23(12), 6725. https://doi.org/10.3390/ijms23126725