Publication: Assigning forensic body fluids to DNA donors in mixed samples by targeted RNA/DNA deep seqeuncing of coding region SNPs using ion torrent technology
Assigning forensic body fluids to DNA donors in mixed samples by targeted RNA/DNA deep seqeuncing of coding region SNPs using ion torrent technology
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Hanson, E., Ingold, S., Dorum, G., Haas, C., Lagace, R., & Ballantyne, J. (2019). Assigning forensic body fluids to DNA donors in mixed samples by targeted RNA/DNA deep seqeuncing of coding region SNPs using ion torrent technology. Forensic Science International: Genetics Supplement Series, 7(1), 23–24. https://doi.org/10.1016/j.fsigss.2019.09.011
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Biological traces found at crime scenes can be analyzed to genetically identify the donor(s) but also to determine the body fluid composition of the stain. The latter can be accomplished with high specificity by mRNA profiling. In some mixed body fluid samples, it might be of probative value to directly associate each body fluid with each of the DNA donors. Associating a DNA profile to the contributing body fluid is not often possible, with the exception of simple binary mixtures that contain male and female specific body fluids. Howe
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Hanson, E., Ingold, S., Dorum, G., Haas, C., Lagace, R., & Ballantyne, J. (2019). Assigning forensic body fluids to DNA donors in mixed samples by targeted RNA/DNA deep seqeuncing of coding region SNPs using ion torrent technology. Forensic Science International: Genetics Supplement Series, 7(1), 23–24. https://doi.org/10.1016/j.fsigss.2019.09.011