Publication: Overcoming Endocytosis Deficiency by Cubosome Nanocarriers
Overcoming Endocytosis Deficiency by Cubosome Nanocarriers
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Prange, J. A., Aleandri, S., Komisarski, M., Luciani, A., Käch, A., Schuh, C.-D., Hall, A. M., Mezzenga, R., Devuyst, O., & Landau, E. M. (2019). Overcoming Endocytosis Deficiency by Cubosome Nanocarriers. ACS Applied Bio Materials, 2(6), 2490–2499. https://doi.org/10.1021/acsabm.9b00187
Abstract
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Abstract
The use of lipid-based nanoparticles for the delivery of biomacromolecules has attracted considerable attention due to the current interest in protein-based therapeutics. Cubosomes protect the incorporated therapeutics, which are susceptible to degradation by enzymes, thereby improving their bioavailability, and concomitantly enhance cellular uptake. The cubosome nanoparticles presented herein were loaded with bovine serum albumin (BSA) and characterized by small-angle X-ray scattering and dynamic light scattering techniques, while th
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- Prange, Jenny A
- Aleandri, Simone
- Komisarski, Marek
- Luciani, Alessandro
- Käch, Andres
- Schuh, Claus-Dieter
- Hall, Andrew M
- Mezzenga, Raffaele
- Devuyst, Olivier
- Landau, Ehud M
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Prange, J. A., Aleandri, S., Komisarski, M., Luciani, A., Käch, A., Schuh, C.-D., Hall, A. M., Mezzenga, R., Devuyst, O., & Landau, E. M. (2019). Overcoming Endocytosis Deficiency by Cubosome Nanocarriers. ACS Applied Bio Materials, 2(6), 2490–2499. https://doi.org/10.1021/acsabm.9b00187
