Publication: Macrophage stimulating protein (MSP) evokes superoxide anion production by human macrophages of different origin
Macrophage stimulating protein (MSP) evokes superoxide anion production by human macrophages of different origin
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Brunelleschi, S., Penengo, L., Lavagno, L., Santoro, C., Colangelo, D., Viano, I., & Gaudino, G. (2001). Macrophage stimulating protein (MSP) evokes superoxide anion production by human macrophages of different origin. British Journal of Pharmacology, 134, 1285–1295. https://doi.org/10.1038/sj.bjp.0704356
Abstract
Abstract
Abstract
1. Macrophage Stimulating Protein (MSP), a serum factor related to Hepatocyte Growth Factor, was originally discovered to stimulate chemotaxis of murine resident peritoneal macrophages. MSP is the ligand for Ron, a member of the Met subfamily of tyrosine kinase receptors. The effects of MSP on human macrophages and the role played in human pathophysiology have long been elusive. 2. We show here that human recombinant MSP (hrMSP) evokes a dose-dependent superoxide anion production in human alveolar and peritoneal macrophages as well as
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Creators (Authors)
- Brunelleschi, S
- Penengo, Lorenza
- Lavagno, L
- Santoro, C
- Colangelo, D
- Viano, I
- Gaudino, G
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Citations
Brunelleschi, S., Penengo, L., Lavagno, L., Santoro, C., Colangelo, D., Viano, I., & Gaudino, G. (2001). Macrophage stimulating protein (MSP) evokes superoxide anion production by human macrophages of different origin. British Journal of Pharmacology, 134, 1285–1295. https://doi.org/10.1038/sj.bjp.0704356
