Publication: Preclinical validation of the micropipette-guided drug administration (MDA) method in the maternal immune activation model of neurodevelopmental disorders
Preclinical validation of the micropipette-guided drug administration (MDA) method in the maternal immune activation model of neurodevelopmental disorders
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Scarborough, J., Mueller, F., Arban, R., Dorner-Ciossek, C., Weber-Stadlbauer, U., Rosenbrock, H., Meyer, U., & Richetto, J. (2020). Preclinical validation of the micropipette-guided drug administration (MDA) method in the maternal immune activation model of neurodevelopmental disorders. Brain, Behavior, and Immunity, 88, 461–470. https://doi.org/10.1016/j.bbi.2020.04.015
Abstract
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Abstract
Pharmacological treatments in laboratory rodents remain a cornerstone of preclinical psychopharmacological research and drug development. There are numerous ways in which acute or chronic pharmacological treatments can be implemented, with each method having certain advantages and drawbacks. Here, we describe and validate a novel treatment method in mice, which we refer to as the micropipette-guided drug administration (MDA) procedure. This administration method is based on a sweetened condensed milk solution as a vehicle for pharmaco
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- Scarborough, Joseph
- Mueller, Flavia
- Arban, Roberto
- Dorner-Ciossek, Cornelia
- Weber-Stadlbauer, Ulrike
- Rosenbrock, Holger
- Meyer, Urs
- Richetto, Juliet
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Scarborough, J., Mueller, F., Arban, R., Dorner-Ciossek, C., Weber-Stadlbauer, U., Rosenbrock, H., Meyer, U., & Richetto, J. (2020). Preclinical validation of the micropipette-guided drug administration (MDA) method in the maternal immune activation model of neurodevelopmental disorders. Brain, Behavior, and Immunity, 88, 461–470. https://doi.org/10.1016/j.bbi.2020.04.015
