Publication: Dexmedetomidine in Psychiatry: Repurposing of its Fast-Acting Anxiolytic, Analgesic and Sleep Modulating Properties
Dexmedetomidine in Psychiatry: Repurposing of its Fast-Acting Anxiolytic, Analgesic and Sleep Modulating Properties
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Bosch, O. G., Dornbierer, D. A., Bavato, F., Quednow, B. B., Landolt, H.-P., & Seifritz, E. (2023). Dexmedetomidine in Psychiatry: Repurposing of its Fast-Acting Anxiolytic, Analgesic and Sleep Modulating Properties. Pharmacopsychiatry, 56(02), 44–50. https://doi.org/10.1055/a-1970-3453
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Drug repurposing is a strategy to identify new indications for already approved drugs. A recent successful example in psychiatry is ketamine, an anesthetic drug developed in the 1960s, now approved and clinically used as a fast-acting antidepressant. Here, we describe the potential of dexmedetomidine as a psychopharmacological repurposing candidate. This α2-adrenoceptor agonist is approved in the US and Europe for procedural sedation in intensive care. It has shown fast-acting inhibitory effects on perioperative stress-related patholo
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Bosch, O. G., Dornbierer, D. A., Bavato, F., Quednow, B. B., Landolt, H.-P., & Seifritz, E. (2023). Dexmedetomidine in Psychiatry: Repurposing of its Fast-Acting Anxiolytic, Analgesic and Sleep Modulating Properties. Pharmacopsychiatry, 56(02), 44–50. https://doi.org/10.1055/a-1970-3453