Publication: Epigenetic modifications in schizophrenia and related disorders: molecular scars of environmental exposures and source of phenotypic variability
Epigenetic modifications in schizophrenia and related disorders: molecular scars of environmental exposures and source of phenotypic variability
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Richetto, J., & Meyer, U. (2021). Epigenetic modifications in schizophrenia and related disorders: molecular scars of environmental exposures and source of phenotypic variability. Biological Psychiatry, 89, 215–226. https://doi.org/10.1016/j.biopsych.2020.03.008
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Epigenetic modifications are increasingly recognized to play a role in the etiology and pathophysiology of schizophrenia and other psychiatric disorders with developmental origins. Here, we summarize clinical and preclinical findings of epigenetic alterations in schizophrenia and relevant disease models and discuss their putative origin. Recent findings suggest that certain schizophrenia risk loci can influence stochastic variation in gene expression through epigenetic processes, highlighting the intricate interaction between genetic
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- Richetto, Juliet
- Meyer, Urs
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Richetto, J., & Meyer, U. (2021). Epigenetic modifications in schizophrenia and related disorders: molecular scars of environmental exposures and source of phenotypic variability. Biological Psychiatry, 89, 215–226. https://doi.org/10.1016/j.biopsych.2020.03.008
