Publication: Treatment of nonunions with nonglycosylated recombinant human bone morphogenetic protein-2 delivered from a fibrin matrix.
Treatment of nonunions with nonglycosylated recombinant human bone morphogenetic protein-2 delivered from a fibrin matrix.
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Schmökel, H. G., Weber, F. E., Seiler, G., von Rechenberg, B., Schense, J. C., Schawalder, P., & Hubbell, J. (2004). Treatment of nonunions with nonglycosylated recombinant human bone morphogenetic protein-2 delivered from a fibrin matrix. Veterinary Surgery, 33(2), 112–118. https://doi.org/10.1111/j.1532-950x.2004.04018.x
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OBJECTIVE: To report the results of the treatment of nonunions with nonglycosylated recombinant human bone morphogenetic protein-2 (nglBMP-2) delivered from a designed fibrin matrix. STUDY DESIGN: Experimental trial in rodents and prospective clinical study in dogs and cats with nonunion fractures. ANIMALS: Twenty adult female, albino, Sprague-Dawley rats; 8 client-owned cats and dogs. METHODS: After development of a fibrin matrix and evaluation of nglBMP-2 in a rodent femoral defect model, 8 consecutive long bone nonunion fractures (
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- Schmökel, H G
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Schmökel, H. G., Weber, F. E., Seiler, G., von Rechenberg, B., Schense, J. C., Schawalder, P., & Hubbell, J. (2004). Treatment of nonunions with nonglycosylated recombinant human bone morphogenetic protein-2 delivered from a fibrin matrix. Veterinary Surgery, 33(2), 112–118. https://doi.org/10.1111/j.1532-950x.2004.04018.x