Publication:

Morphological and Quantitative Parametric MRI Follow-up of Cartilage Changes Before and After Intra-articular Injection Therapy in Patients With Mild to Moderate Knee Osteoarthritis: A Randomized, Placebo-Controlled Trial

Date

Date

Date
2024
Journal Article
Published version

Citations

Citation copied

Tschopp, M., Pfirrmann, C. W. A., Brunner, F., Fucentese, S. F., Galley, J., Stern, C., Sutter, R., Catanzaro, S., Kuhne, N., & Rosskopf, A. B. (2024). Morphological and Quantitative Parametric MRI Follow-up of Cartilage Changes Before and After Intra-articular Injection Therapy in Patients With Mild to Moderate Knee Osteoarthritis: A Randomized, Placebo-Controlled Trial. Investigative Radiology, 59(9), 646–655. https://doi.org/10.1097/RLI.0000000000001067

Abstract

Abstract

Abstract

BACKGROUND: Intra-articular injections are routinely used for conservative treatment of knee osteoarthritis (OA). The detailed comparative therapeutic effects of these injections on cartilage tissue are still unclear. OBJECTIVE: The aim of this study was to detect and compare knee cartilage changes after intra-articular injection of glucocorticoid, hyaluronic acid, or platelet-rich plasma (PRP) to placebo using quantitative (T2 and T2* mapping) and morphological magnetic resonance imaging parameters in patients with mild or moderate o

Additional indexing

Creators (Authors)

  • Tschopp, Marcel
    affiliation.icon.alt
  • Pfirrmann, Christian W A
    affiliation.icon.alt
  • Brunner, Florian
    affiliation.icon.alt
  • Fucentese, Sandro F
    affiliation.icon.alt
  • Galley, Julien
    affiliation.icon.alt
  • Stern, Christoph
    affiliation.icon.alt
  • Sutter, Reto
    affiliation.icon.alt
  • Catanzaro, Sabrina
    affiliation.icon.alt
  • Kuhne, Nathalie
    affiliation.icon.alt
  • Rosskopf, Andrea B
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
59

Number

Number

Number
9

Page range/Item number

Page range/Item number

Page range/Item number
646

Page end

Page end

Page end
655

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

Osteoarthritis, Knee/diagnostic imaging/drug therapy, Magnetic Resonance Imaging/methods, Injections, Intra-Articular, Double-Blind Method, Hyaluronic Acid/administration & dosage, Platelet-Rich Plasma, Treatment Outcome, Cartilage, Articular/diagnostic imaging/drug effects/pathology, Glucocorticoids/administration & dosage/therapeutic use, Follow-Up Studies

Language

Language

Language
English

Publication date

Publication date

Publication date
2024-09

Date available

Date available

Date available
2025-01-29

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
0020-9996

OA Status

OA Status

OA Status
Hybrid

Free Access at

Free Access at

Free Access at
DOI

PubMed ID

PubMed ID

PubMed ID

Citations

Citation copied

Tschopp, M., Pfirrmann, C. W. A., Brunner, F., Fucentese, S. F., Galley, J., Stern, C., Sutter, R., Catanzaro, S., Kuhne, N., & Rosskopf, A. B. (2024). Morphological and Quantitative Parametric MRI Follow-up of Cartilage Changes Before and After Intra-articular Injection Therapy in Patients With Mild to Moderate Knee Osteoarthritis: A Randomized, Placebo-Controlled Trial. Investigative Radiology, 59(9), 646–655. https://doi.org/10.1097/RLI.0000000000001067

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