Publication: Morphological and Quantitative Parametric MRI Follow-up of Cartilage Changes Before and After Intra-articular Injection Therapy in Patients With Mild to Moderate Knee Osteoarthritis: A Randomized, Placebo-Controlled Trial
Morphological and Quantitative Parametric MRI Follow-up of Cartilage Changes Before and After Intra-articular Injection Therapy in Patients With Mild to Moderate Knee Osteoarthritis: A Randomized, Placebo-Controlled Trial
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Tschopp, M., Pfirrmann, C. W. A., Brunner, F., Fucentese, S. F., Galley, J., Stern, C., Sutter, R., Catanzaro, S., Kuhne, N., & Rosskopf, A. B. (2024). Morphological and Quantitative Parametric MRI Follow-up of Cartilage Changes Before and After Intra-articular Injection Therapy in Patients With Mild to Moderate Knee Osteoarthritis: A Randomized, Placebo-Controlled Trial. Investigative Radiology, 59(9), 646–655. https://doi.org/10.1097/RLI.0000000000001067
Abstract
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BACKGROUND: Intra-articular injections are routinely used for conservative treatment of knee osteoarthritis (OA). The detailed comparative therapeutic effects of these injections on cartilage tissue are still unclear. OBJECTIVE: The aim of this study was to detect and compare knee cartilage changes after intra-articular injection of glucocorticoid, hyaluronic acid, or platelet-rich plasma (PRP) to placebo using quantitative (T2 and T2* mapping) and morphological magnetic resonance imaging parameters in patients with mild or moderate o
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Tschopp, M., Pfirrmann, C. W. A., Brunner, F., Fucentese, S. F., Galley, J., Stern, C., Sutter, R., Catanzaro, S., Kuhne, N., & Rosskopf, A. B. (2024). Morphological and Quantitative Parametric MRI Follow-up of Cartilage Changes Before and After Intra-articular Injection Therapy in Patients With Mild to Moderate Knee Osteoarthritis: A Randomized, Placebo-Controlled Trial. Investigative Radiology, 59(9), 646–655. https://doi.org/10.1097/RLI.0000000000001067