Publication: Forces controlling organ growth and size
Forces controlling organ growth and size
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Eder, D., Aegerter, C., & Basler, K. (2017). Forces controlling organ growth and size. Mechanisms of Development, 144, 53–61. https://doi.org/10.1016/j.mod.2016.11.005
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One of the fundamental questions in developmental biology is what determines the final size and shape of an organ. Recent research strongly emphasizes that besides cell-cell communication, biophysical principals govern organ development. The architecture and mechanics of a tissue guide cellular processes such as movement, growth or differentiation. Furthermore, mechanical cues do not only regulate processes at a cellular level but also provide constant feedback about size and shape on a tissue scale. Here we review several models and
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Eder, D., Aegerter, C., & Basler, K. (2017). Forces controlling organ growth and size. Mechanisms of Development, 144, 53–61. https://doi.org/10.1016/j.mod.2016.11.005