mRNA profiling of mock casework samples: Results of a FoRNAP collaborative exercise

Salzmann, Andrea Patrizia; Bamberg, Malte; Courts, Cornelius; Dorum, Guro; Gosch, Annica; Hadrys, Thorsten; Hadzic, Gavrilo; Neis, Maximilian; Schneider, Peter M; Sijen, Titia; van den Berge, Margreet; Wiegand, Peter; Haas, Cordula

doi:10.1016/j.fsigen.2020.102409

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Salzmann, A. P., Bamberg, M., Courts, C., Dorum, G., Gosch, A., Hadrys, T., Hadzic, G., Neis, M., Schneider, P. M., Sijen, T., van den Berge, M., Wiegand, P., & Haas, C. (2021). mRNA profiling of mock casework samples: Results of a FoRNAP collaborative exercise. Forensic Science International. Genetics, 50, 102409. https://doi.org/10.1016/j.fsigen.2020.102409

Abstract

In recent years, forensic mRNA profiling has increasingly been used to identify the origin of human body fluids. By now, several laboratories have implemented mRNA profiling and also use it in criminal casework. In 2018 the FoRNAP (Forensic RNA Profiling) group was established among a number of these laboratories with the aim of sharing experiences, discussing optimization potential, identifying challenges and suggesting solutions with regards to mRNA profiling and casework. To compare mRNA profiling methods and results a collaborativ