Publication: The impact of levamisole and alcohol on white matter microstructure in adult chronic cocaine users
The impact of levamisole and alcohol on white matter microstructure in adult chronic cocaine users
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Michels, L., Moisa, M., Stämpfli, P., Hirsiger, S., Baumgartner, M. R., Surbeck, W., Seifritz, E., & Quednow, B. B. (2022). The impact of levamisole and alcohol on white matter microstructure in adult chronic cocaine users. Addiction Biology, 27(3), e13149. https://doi.org/10.1111/adb.13149
Abstract
Abstract
Abstract
Previous brain imaging studies with chronic cocaine users (CU) using diffusion tensor imaging (DTI) mostly focused on fractional anisotropy to investigate white matter (WM) integrity. However, a quantitative interpretation of fractional anisotropy (FA) alterations is often impeded by the inherent limitations of the underlying tensor model. A more fine-grained measure of WM alterations could be achieved by measuring fibre density (FD). This study investigates this novel DTI metric comparing 23 chronic CU and 32 healthy subjects. Quanti
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- Michels, Lars
- Stämpfli, Philipp
- Hirsiger, Sarah
- Surbeck, Werner
- Seifritz, Erich
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Michels, L., Moisa, M., Stämpfli, P., Hirsiger, S., Baumgartner, M. R., Surbeck, W., Seifritz, E., & Quednow, B. B. (2022). The impact of levamisole and alcohol on white matter microstructure in adult chronic cocaine users. Addiction Biology, 27(3), e13149. https://doi.org/10.1111/adb.13149
