Publication: Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus
Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus
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Ozga, A. T., Nieves-Colón, M. A., Honap, T. P., Sankaranarayanan, K., Hofman, C. A., Milner, G. R., Lewis, C. M., Stone, A. C., & Warinner, C. (2016). Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus. American Journal of Physical Anthropology, 160(2), 220–228. https://doi.org/10.1002/ajpa.22960
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OBJECTIVES: Archaeological dental calculus is a rich source of host-associated biomolecules. Importantly, however, dental calculus is more accurately described as a calcified microbial biofilm than a host tissue. As such, concerns regarding destructive analysis of human remains may not apply as strongly to dental calculus, opening the possibility of obtaining human health and ancestry information from dental calculus in cases where destructive analysis of conventional skeletal remains is not permitted. Here we investigate the preserva
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- Nieves-Colón, Maria A
- Honap, Tanvi P
- Milner, George R
- Stone, Anne C
- Warinner, Christina
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Ozga, A. T., Nieves-Colón, M. A., Honap, T. P., Sankaranarayanan, K., Hofman, C. A., Milner, G. R., Lewis, C. M., Stone, A. C., & Warinner, C. (2016). Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus. American Journal of Physical Anthropology, 160(2), 220–228. https://doi.org/10.1002/ajpa.22960
