Publication: 3D mechanical characterization of single cells and small organisms using acoustic manipulation and force microscopy
3D mechanical characterization of single cells and small organisms using acoustic manipulation and force microscopy
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Läubli, N. F., Burri, J. T., Marquard, J., Vogler, H., Mosca, G., Vertti-Quintero, N., Shamsudhin, N., deMello, A., Grossniklaus, U., Ahmed, D., & Nelson, B. J. (2021). 3D mechanical characterization of single cells and small organisms using acoustic manipulation and force microscopy. Nature Communications, 12, 2583. https://doi.org/10.1038/s41467-021-22718-8
Abstract
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Abstract
Quantitative micromechanical characterization of single cells and multicellular tissues or organisms is of fundamental importance to the study of cellular growth, morphogenesis, and cell-cell interactions. However, due to limited manipulation capabilities at the microscale, systems used for mechanical characterizations struggle to provide complete three-dimensional coverage of individual specimens. Here, we combine an acoustically driven manipulation device with a micro-force sensor to freely rotate biological samples and quantify mec
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- Läubli, Nino F
- Burri, Jan T
- Marquard, Julian
- Vogler, Hannes
- Mosca, Gabriella
- Vertti-Quintero, Nadia
- Shamsudhin, Naveen
- deMello, Andrew
- Grossniklaus, Ueli
- Ahmed, Daniel
- Nelson, Bradley J
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Läubli, N. F., Burri, J. T., Marquard, J., Vogler, H., Mosca, G., Vertti-Quintero, N., Shamsudhin, N., deMello, A., Grossniklaus, U., Ahmed, D., & Nelson, B. J. (2021). 3D mechanical characterization of single cells and small organisms using acoustic manipulation and force microscopy. Nature Communications, 12, 2583. https://doi.org/10.1038/s41467-021-22718-8
