Publication: Increased levels of midbrain immune-related transcripts in schizophrenia and in murine offspring after maternal immune activation
Increased levels of midbrain immune-related transcripts in schizophrenia and in murine offspring after maternal immune activation
Date
Date
Date
Citations
Purves-Tyson, T. D., Weber-Stadlbauer, U., Richetto, J., Rothmond, D. A., Labouesse, M. A., Polesel, M., Robinson, K., Shannon Weickert, C., & Meyer, U. (2021). Increased levels of midbrain immune-related transcripts in schizophrenia and in murine offspring after maternal immune activation. Molecular Psychiatry, 26(3), 849–863. https://doi.org/10.1038/s41380-019-0434-0
Abstract
Abstract
Abstract
The pathophysiology of dopamine dysregulation in schizophrenia involves alterations at the ventral midbrain level. Given that inflammatory mediators such as cytokines influence the functional properties of midbrain dopamine neurons, midbrain inflammation may play a role in schizophrenia by contributing to presynaptic dopamine abnormalities. Thus, we quantified inflammatory markers in dopaminergic areas of the midbrain of people with schizophrenia and matched controls. We also measured these markers in midbrain of mice exposed to mater
Metrics
Views
Additional indexing
Creators (Authors)
- Purves-Tyson, Tertia D
- Weber-Stadlbauer, Ulrike
- Richetto, Juliet
- Rothmond, Debora A
- Labouesse, Marie A
- Polesel, Marcello
- Robinson, Kate
- Shannon Weickert, Cynthia
- Meyer, Urs
Volume
Volume
Volume
Number
Number
Number
Page range/Item number
Page range/Item number
Page range/Item number
Page end
Page end
Page end
Item Type
Item Type
Item Type
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Keywords
Language
Language
Language
Publication date
Publication date
Publication date
Date available
Date available
Date available
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
OA Status
OA Status
OA Status
Free Access at
Free Access at
Free Access at
Publisher DOI
Metrics
Views
Citations
Purves-Tyson, T. D., Weber-Stadlbauer, U., Richetto, J., Rothmond, D. A., Labouesse, M. A., Polesel, M., Robinson, K., Shannon Weickert, C., & Meyer, U. (2021). Increased levels of midbrain immune-related transcripts in schizophrenia and in murine offspring after maternal immune activation. Molecular Psychiatry, 26(3), 849–863. https://doi.org/10.1038/s41380-019-0434-0
