Publication: An unexpected finding: younger fathers have a higher risk for offspring with chromosomal aneuploidies
An unexpected finding: younger fathers have a higher risk for offspring with chromosomal aneuploidies
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Steiner, B., Masood, R., Rufibach, K., Niedrist, D., Kundert, O., Riegel, M., & Schinzel, A. (2015). An unexpected finding: younger fathers have a higher risk for offspring with chromosomal aneuploidies. European Journal of Human Genetics, 23(4), 466–472. https://doi.org/10.1038/ejhg.2014.122
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The past decades have seen a remarkable shift in the demographics of childbearing in Western countries. The risk for offspring with chromosomal aneuploidies with advancing maternal age is well known, but most studies failed to demonstrate a paternal age effect. Retrospectively, we analyzed two case data sets containing parental ages from pre- and postnatal cases with trisomies 21, 13 and 18. The reference data set contains the parental ages of the general Swiss population. We dichotomized all couples into two distinct groups. In the f
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- Steiner, Bernhard
- Masood, Rahim
- Rufibach, Kaspar
- Kundert, Oliver
- Riegel, Mariluce
- Schinzel, Albert
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Steiner, B., Masood, R., Rufibach, K., Niedrist, D., Kundert, O., Riegel, M., & Schinzel, A. (2015). An unexpected finding: younger fathers have a higher risk for offspring with chromosomal aneuploidies. European Journal of Human Genetics, 23(4), 466–472. https://doi.org/10.1038/ejhg.2014.122
