Publication: Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe.
Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe.
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Schuenemann, V. J., Avanzi, C., Krause-Kyora, B., Seitz, A., Herbig, A., Inskip, S., Bonazzi, M., Reiter, E., Urban, C., Dangvard Pedersen, D., Taylor, G. M., Singh, P., Stewart, G. R., Velemínský, P., Likovsky, J., Marcsik, A., Molnár, E., Pálfi, G., Mariotti, V., … Krause, J. (2018). Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe. PLoS Pathogens, 14(5), e1006997. https://doi.org/10.1371/journal.ppat.1006997
Abstract
Abstract
Abstract
Studying ancient DNA allows us to retrace the evolutionary history of human pathogens, such as Mycobacterium leprae, the main causative agent of leprosy. Leprosy is one of the oldest recorded and most stigmatizing diseases in human history. The disease was prevalent in Europe until the 16th century and is still endemic in many countries with over 200,000 new cases reported annually. Previous worldwide studies on modern and European medieval M. leprae genomes revealed that they cluster into several distinct branches of which two were p
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Creators (Authors)
- Schuenemann, Verena J
- Avanzi, Charlotte
- Krause-Kyora, Ben
- Seitz, Alexander
- Herbig, Alexander
- Inskip, Sarah
- Bonazzi, Marion
- Reiter, Ella
- Urban, Christian
- Dangvard Pedersen, Dorthe
- Taylor, G Michael
- Singh, Pushpendra
- Stewart, Graham R
- Velemínský, Petr
- Likovsky, Jakub
- Marcsik, Antónia
- Molnár, Erika
- Pálfi, György
- Mariotti, Valentina
- Riga, Alessandro
- Belcastro, M Giovanna
- Boldsen, Jesper L
- Nebel, Almut
- Mays, Simon
- Donoghue, Helen D
- Zakrzewski, Sonia
- Benjak, Andrej
- Nieselt, Kay
- Cole, Stewart T
- Krause, Johannes
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Citations
Schuenemann, V. J., Avanzi, C., Krause-Kyora, B., Seitz, A., Herbig, A., Inskip, S., Bonazzi, M., Reiter, E., Urban, C., Dangvard Pedersen, D., Taylor, G. M., Singh, P., Stewart, G. R., Velemínský, P., Likovsky, J., Marcsik, A., Molnár, E., Pálfi, G., Mariotti, V., … Krause, J. (2018). Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe. PLoS Pathogens, 14(5), e1006997. https://doi.org/10.1371/journal.ppat.1006997
