Publication:

Development and validation of a liquid chromatography–tandem mass spectrometry (LC–MS/MS) method including 25 novel synthetic opioids in hair and subsequent analysis of a Swiss opioid consumer cohort

Date

Date

Date
2024
Journal Article
Published version

Citations

Citation copied

Polke, M., Concheiro, M., Cooper, G., Bogdal, C., Baumgartner, M. R., Krämer, T., & Binz, T. M. (2024). Development and validation of a liquid chromatography–tandem mass spectrometry (LC–MS/MS) method including 25 novel synthetic opioids in hair and subsequent analysis of a Swiss opioid consumer cohort. Drug Testing and Analysis, 16(11), 1384–1391. https://doi.org/10.1002/dta.3663

Abstract

Abstract

Abstract

Major public health concern is raised by the evidence that common drugs like heroin are now frequently laced or replaced with highly potent novel synthetic opioids (NSOs). The objective of this study was to explore the prevalence and patterns of NSOs in a cohort of Swiss opioid users by hair analysis. Hair analysis is considered an ideal tool for retrospective consumption monitoring. Hair samples from 439 opioid users in Zurich were analyzed. Study inclusion required a previous positive hair test result for heroin metabolites, oxycodo

Metrics

Downloads

4 since deposited on 2024-03-22
Acq. date: 2025-11-12

Views

5 since deposited on 2024-03-22
2last week
Acq. date: 2025-11-12

Additional indexing

Creators (Authors)

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
16

Number

Number

Number
11

Page range/Item number

Page range/Item number

Page range/Item number
1384

Page end

Page end

Page end
1391

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

Spectroscopy, Pharmaceutical Science, Environmental Chemistry, Analytical Chemistry fentanyl, hair analysis, LC–MS/MS, NSOs, Switzerland

Language

Language

Language
English

Publication date

Publication date

Publication date
2024-11-01

Date available

Date available

Date available
2024-03-22

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1942-7603

Additional Information

Additional Information

Additional Information
ACKNOWLEDGMENTS The authors thankfully acknowledge the support of the project by the Scientific Exchange Grant (No. IZSEZ0_188514/1) from the Swiss National Science Foundation. Sincere appreciation is also extended to the DIZ for graciously providing their database concerning tested NSOs and NPS. Open access funding provided by Universitat Zurich.

OA Status

OA Status

OA Status
Hybrid

Free Access at

Free Access at

Free Access at
DOI

PubMed ID

PubMed ID

PubMed ID

Metrics

Downloads

4 since deposited on 2024-03-22
Acq. date: 2025-11-12

Views

5 since deposited on 2024-03-22
2last week
Acq. date: 2025-11-12

Citations

Citation copied

Polke, M., Concheiro, M., Cooper, G., Bogdal, C., Baumgartner, M. R., Krämer, T., & Binz, T. M. (2024). Development and validation of a liquid chromatography–tandem mass spectrometry (LC–MS/MS) method including 25 novel synthetic opioids in hair and subsequent analysis of a Swiss opioid consumer cohort. Drug Testing and Analysis, 16(11), 1384–1391. https://doi.org/10.1002/dta.3663

Hybrid Open Access
Loading...
Thumbnail Image

Files

Files

Files
Files available to download:1

Files

Files

Files
Files available to download:1
Loading...
Thumbnail Image