Publication: Impact of prenatal diagnosis on the prevalence of live births with Down syndrome in the eastern half of Switzerland 1980-1996
Impact of prenatal diagnosis on the prevalence of live births with Down syndrome in the eastern half of Switzerland 1980-1996
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Binkert, F., Mutter, M., & Schinzel, A. (2002). Impact of prenatal diagnosis on the prevalence of live births with Down syndrome in the eastern half of Switzerland 1980-1996. Swiss Medical Weekly, 132, 478–484. https://smw.ch/article/doi/smw.2002.10009
Abstract
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Abstract
OBJECTIVES AND METHODS
To investigate the impact of prenatal diagnosis on trisomy 21 live births, we collected all prenatal and postnatal trisomy 21 cases (n = 1096) in the eastern half of Switzerland for the years 1980-1996.
RESULTS
Despite increasing prenatal detection rates of trisomy 21 foetuses (an increase of 169% in the last 5 versus the first 5 years of the study period) and subsequent termination of pregnancies, the number of liveborn Down syndrome children remained constant. The reason is a shift towards a higher mean mat
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Citations
Binkert, F., Mutter, M., & Schinzel, A. (2002). Impact of prenatal diagnosis on the prevalence of live births with Down syndrome in the eastern half of Switzerland 1980-1996. Swiss Medical Weekly, 132, 478–484. https://smw.ch/article/doi/smw.2002.10009