Assessment of intermediate coronary lesions by fractional flow reserve and quantitative flow ratio in patients with small-vessel disease

Erbay, Aslihan; Steiner, Julia; Lauten, Alexander; Landmesser, Ulf; Leistner, David M; Stähli, Barbara E

doi:10.1002/ccd.28531

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Erbay, A., Steiner, J., Lauten, A., Landmesser, U., Leistner, D. M., & Stähli, B. E. (2020). Assessment of intermediate coronary lesions by fractional flow reserve and quantitative flow ratio in patients with small-vessel disease. Catheterization and Cardiovascular Interventions, 96(4), 743–751. https://doi.org/10.1002/ccd.28531

Abstract

BACKGROUND

Quantitative flow ratio (QFR) has recently been introduced as a novel, less-invasive, adenosine-free measure for functional coronary lesion assessment. Whether reference vessel dimensions affect functional lesion assessment is uncertain.

METHODS

A total of 436 patients with 516 interrogated coronary vessels by means of FFR were included in the study. Patients were dichotomized according to the median reference vessel diameter (group 1: ≤2.8 mm and group 2: >2.8 mm). QFR analyses were performed offline at the institution'