Publication: Daily Caffeine Intake Induces Concentration-Dependent Medial Temporal Plasticity in Humans: A Multimodal Double-Blind Randomized Controlled Trial
Daily Caffeine Intake Induces Concentration-Dependent Medial Temporal Plasticity in Humans: A Multimodal Double-Blind Randomized Controlled Trial
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Lin, Y.-S., Weibel, J., Landolt, H.-P., Santini, F., Meyer, M., Brunmair, J., Meier-Menches, S. M., Gerner, C., Borgwardt, S., Cajochen, C., & Reichert, C. (2021). Daily Caffeine Intake Induces Concentration-Dependent Medial Temporal Plasticity in Humans: A Multimodal Double-Blind Randomized Controlled Trial. Cerebral Cortex, 31(6), 3096–3106. https://doi.org/10.1093/cercor/bhab005
Abstract
Abstract
Abstract
Caffeine is commonly used to combat high sleep pressure on a daily basis. However, interference with sleep–wake regulation could disturb neural homeostasis and insufficient sleep could lead to alterations in human gray matter. Hence, in this double-blind, randomized, cross-over study, we examined the impact of 10-day caffeine (3 × 150 mg/day) on human gray matter volumes (GMVs) and cerebral blood flow (CBF) by fMRI MP-RAGE and arterial spin-labeling sequences in 20 habitual caffeine consumers, compared with 10-day placebo (3 × 150 mg/
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Creators (Authors)
- Lin, Yu-Shiuan
- Weibel, Janine
- Landolt, Hans-Peter
- Santini, Francesco
- Meyer, Martin
- Brunmair, Julia
- Meier-Menches, Samuel M
- Gerner, Christopher
- Borgwardt, Stefan
- Cajochen, Christian
- Reichert, Carolin
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Citations
Lin, Y.-S., Weibel, J., Landolt, H.-P., Santini, F., Meyer, M., Brunmair, J., Meier-Menches, S. M., Gerner, C., Borgwardt, S., Cajochen, C., & Reichert, C. (2021). Daily Caffeine Intake Induces Concentration-Dependent Medial Temporal Plasticity in Humans: A Multimodal Double-Blind Randomized Controlled Trial. Cerebral Cortex, 31(6), 3096–3106. https://doi.org/10.1093/cercor/bhab005
