Publication: Multifactorial Contribution of Notch Signaling in Head and Neck Squamous Cell Carcinoma
Multifactorial Contribution of Notch Signaling in Head and Neck Squamous Cell Carcinoma
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Porcheri, C., Meisel, C. T., & Mitsiadis, T. (2019). Multifactorial Contribution of Notch Signaling in Head and Neck Squamous Cell Carcinoma. International Journal of Molecular Sciences, 20(6), 1520. https://doi.org/10.3390/ijms20061520
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Abstract
Head and neck squamous cell carcinoma (HNSCC) defines a group of solid tumors originating from the mucosa of the upper aerodigestive tract, pharynx, larynx, mouth, and nasal cavity. It has a metastatic evolution and poor prognosis and is the sixth most common cancer in the world, with 600,000 new cases reported every year. HNSCC heterogeneity and complexity is reflected in a multistep progression, involving crosstalk between several molecular pathways. The Notch pathway is associated with major events supporting cancerogenic evolution
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- Porcheri, Cristina
- Meisel, Christian Thomas
- Mitsiadis, Thimios
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Porcheri, C., Meisel, C. T., & Mitsiadis, T. (2019). Multifactorial Contribution of Notch Signaling in Head and Neck Squamous Cell Carcinoma. International Journal of Molecular Sciences, 20(6), 1520. https://doi.org/10.3390/ijms20061520
