Publication: Non-destructive extraction of DNA from preserved tissues in medical collections
Non-destructive extraction of DNA from preserved tissues in medical collections
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Rayo, E., Ferrari, G., Neukamm, J., Akgül, G., Breidenstein, A. M., Cooke, M., Phillips, C., Bouwman, A. S., Rühli, F. J., & Schuenemann, V. J. (2022). Non-destructive extraction of DNA from preserved tissues in medical collections. BioTechniques, 72(2), 60–64. https://doi.org/10.2144/btn-2021-0014
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Museum specimens and histologically fixed material are valuable samples for the study of historical soft tissues and represent a possible pathogen-specific source for retrospective molecular investigations. However, current methods for molecular analysis are inherently destructive, posing a dilemma between performing a study with the available technology, thus damaging the sample, and conserving the material for future investigations. Here the authors present the first tests of a non-destructive alternative that facilitates genetic an
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Rayo, E., Ferrari, G., Neukamm, J., Akgül, G., Breidenstein, A. M., Cooke, M., Phillips, C., Bouwman, A. S., Rühli, F. J., & Schuenemann, V. J. (2022). Non-destructive extraction of DNA from preserved tissues in medical collections. BioTechniques, 72(2), 60–64. https://doi.org/10.2144/btn-2021-0014