Publication:

Pharmacotherapy of cardiovascular diseases from herbs and pills to nucleic acids

Date

Date

Date
2025
Journal Article
Published version

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Landmesser, U., Thum, T., Tokgözoğlu, L., Guzik, T. J., Cosentino, F., Hajjar, R., Goncalves, A., Laguna-Fernandez, A., Nioi, P., Prochaska, J. H., Rocha, R., Kathiresan, S., März Julian Werner, Maurer, M. S., O’Donnell, C. J., Passacquale, G., Tavridou, A., Van Heetvelde, M., Himmelmann, A., … Lüscher, T. F. (2025). Pharmacotherapy of cardiovascular diseases from herbs and pills to nucleic acids. European Heart Journal, Epub ahead of print. https://doi.org/10.1093/eurheartj/ehaf520

Abstract

Abstract

Abstract

Cardiovascular (CV) diseases continue to cause substantial morbidity and mortality. Risk factors are inadequately controlled, compliance with medication remains suboptimal, and treatments are not sufficient to fully prevent the progression of atherosclerotic CV disease, heart failure, arrhythmias, and valvular heart diseases. An increased understanding of the genetic basis of CV diseases and advances in the technology of therapeutics have led to the development of nucleic acid–based therapies (NATs) for prevention and treatment of CV

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Creators (Authors)

  • Landmesser, Ulf
  • Thum, Thomas
  • Tokgözoğlu, Lale
  • Guzik, Tomasz J
  • Cosentino, Francesco
  • Hajjar, Roger
  • Goncalves, Alexandra
  • Laguna-Fernandez, Andres
  • Nioi, Paul
  • Prochaska, Jürgen H
  • Rocha, Ricardo
  • Kathiresan, Sekar
  • März Julian Werner
  • Maurer, Mathew S
  • O’Donnell, Christopher J
  • Passacquale, Gabriella
  • Tavridou, Anna
  • Van Heetvelde, Mattias
  • Himmelmann, Anders
  • Meder, Benjamin
  • Roessig, Lothar
  • Crea, Filippo
  • Lüscher, Thomas F

Journal/Series Title

Journal/Series Title

Journal/Series Title

Page range/Item number

Page range/Item number

Page range/Item number
Epub ahead of print

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Keywords

Atherosclerotic cardiovascular disease, CRISPR, Gene therapies, Heart failure, Nucleic acid–based therapies, RNA-targeted therapeutics, Transthyretin cardiac amyloidosis

Language

Language

Language
English

Publication date

Publication date

Publication date
2025-08-21

Date available

Date available

Date available
2025-10-14

Publisher

Publisher

Publisher
Oxford University Press

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
0195-668X

OA Status

OA Status

OA Status
Closed

Free Access at

Free Access at

Free Access at
Unspecified

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PubMed ID

PubMed ID

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Landmesser, U., Thum, T., Tokgözoğlu, L., Guzik, T. J., Cosentino, F., Hajjar, R., Goncalves, A., Laguna-Fernandez, A., Nioi, P., Prochaska, J. H., Rocha, R., Kathiresan, S., März Julian Werner, Maurer, M. S., O’Donnell, C. J., Passacquale, G., Tavridou, A., Van Heetvelde, M., Himmelmann, A., … Lüscher, T. F. (2025). Pharmacotherapy of cardiovascular diseases from herbs and pills to nucleic acids. European Heart Journal, Epub ahead of print. https://doi.org/10.1093/eurheartj/ehaf520

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