Publication: The ciliopathy protein CC2D2A Associates with NINL and functions in RAB8-MICAL3-regulated vesicle trafficking
Date
Date
Date
2015
Journal Article
Published version
Abstract
Abstract
Abstract
Ciliopathies are a group of human disorders caused by dysfunction of primary cilia, ubiquitous microtubule-based organelles involved in transduction of extra-cellular signals to the cell. This function requires the concentration of receptors and channels in the ciliary membrane, which is achieved by complex trafficking mechanisms, in part controlled by the small GTPase RAB8, and by sorting at the transition zone located at the entrance of the ciliary compartment. Mutations in the transition zone gene CC2D2A cause the related Joubert a
Additional indexing
Creators (Authors)
- Dona, Margo
- Hetterschijt, Lisette
- Tonnaer, Edith
- Peters, Theo
- de Vrieze, Erik
- Mans, Dorus A
- van Beersum, Sylvia E C
- Phelps, Ian G
- Arts, Heleen H
- Keunen, Jan E
- Ueffing, Marius
- Roepman, Ronald
- Boldt, Karsten
- Doherty, Dan
- Moens, Cecilia B
- Kremer, Hannie
- van Wijk, Erwin
Volume
Volume
Volume
11
Number
Number
Number
10
Page range/Item number
Page range/Item number
Page range/Item number
e1005575
Item Type
Item Type
Item Type
Journal Article
Language
Language
Language
English
Publication date
Publication date
Publication date
2015-10
Date available
Date available
Date available
2015-12-10
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
1553-7390
OA Status
OA Status
OA Status
Gold
Free Access at
Free Access at
Free Access at
Pubmed ID
Publisher DOI
Gold Open Access
Loading...
