Publication: Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study
Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study
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Citations
Bancos, I., Taylor, A. E., Chortis, V., et al, & Beuschlein, F. (2020). Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study. The Lancet. Diabetes & Endocrinology, 8(9), 733–781. https://doi.org/10.1016/S2213-8587(20)30218-7
Abstract
Abstract
Abstract
BACKGROUND
Cross-sectional imaging regularly results in incidental discovery of adrenal tumours, requiring exclusion of adrenocortical carcinoma (ACC). However, differentiation is hampered by poor specificity of imaging characteristics. We aimed to validate a urine steroid metabolomics approach, using steroid profiling as the diagnostic basis for ACC.
METHODS
We did a prospective multicentre study in adult participants (age ≥18 years) with newly diagnosed adrenal masses. We assessed the accuracy of diagnostic imaging strategies bas
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Creators (Authors)
- Bancos, Irina
- Taylor, Angela E
- Chortis, Vasileios
- et al
- Beuschlein, Felix
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Citations
Bancos, I., Taylor, A. E., Chortis, V., et al, & Beuschlein, F. (2020). Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study. The Lancet. Diabetes & Endocrinology, 8(9), 733–781. https://doi.org/10.1016/S2213-8587(20)30218-7
