Publication: Circulating FABP4 Is a prognostic biomarker in patients with acute coronary syndrome but not in asymptomatic individuals
Circulating FABP4 Is a prognostic biomarker in patients with acute coronary syndrome but not in asymptomatic individuals
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Reiser, H., Klingenberg, R., Hof, D., Cooksley-Decasper, S., Fuchs, N., Akhmedov, A., Zoller, S., Marques-Vidal, P., Marti Soler, H., Heg, D., Landmesser, U., Rodondi, N., Mach, F., Windecker, S., Vollenweider, P., Matter, C. M., Lüscher, T. F., von Eckardstein, A., & Gawinecka, J. (2015). Circulating FABP4 Is a prognostic biomarker in patients with acute coronary syndrome but not in asymptomatic individuals. Arteriosclerosis, Thrombosis, and Vascular Biology, 35(8), 1872–1879. https://doi.org/10.1161/ATVBAHA.115.305365
Abstract
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Abstract
OBJECTIVE: Blood-borne biomarkers reflecting atherosclerotic plaque burden have great potential to improve clinical management of atherosclerotic coronary artery disease and acute coronary syndrome (ACS). APPROACH AND RESULTS: Using data integration from gene expression profiling of coronary thrombi versus peripheral blood mononuclear cells and proteomic analysis of atherosclerotic plaque-derived secretomes versus healthy tissue secretomes, we identified fatty acid-binding protein 4 (FABP4) as a biomarker candidate for coronary artery
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Creators (Authors)
- Reiser, Hans
- Klingenberg, Roland
- Hof, Danielle
- Cooksley-Decasper, Seraina
- Fuchs, Nina
- Akhmedov, Alexander
- Zoller, Stefan
- Marques-Vidal, Pedro
- Marti Soler, Helena
- Landmesser, Ulf
- Rodondi, Nicolas
- Mach, Francois
- Windecker, Stephan
- Vollenweider, Peter
- Matter, Christian M
- Lüscher, Thomas F
- von Eckardstein, Arnold
- Gawinecka, Joanna
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Reiser, H., Klingenberg, R., Hof, D., Cooksley-Decasper, S., Fuchs, N., Akhmedov, A., Zoller, S., Marques-Vidal, P., Marti Soler, H., Heg, D., Landmesser, U., Rodondi, N., Mach, F., Windecker, S., Vollenweider, P., Matter, C. M., Lüscher, T. F., von Eckardstein, A., & Gawinecka, J. (2015). Circulating FABP4 Is a prognostic biomarker in patients with acute coronary syndrome but not in asymptomatic individuals. Arteriosclerosis, Thrombosis, and Vascular Biology, 35(8), 1872–1879. https://doi.org/10.1161/ATVBAHA.115.305365
