Integrative Analysis of Acute and Chronic In Vivo Fibrosing Interstitial Lung Disease Using Image- and Molecular-Based Omics Approaches

Abstract

Progressive fibrosing interstitial lung disease (PF-ILD) is characterized by irreversible scarring and inflammation of lung tissue, resulting in a gradual loss of pulmonary function and eventually respiratory failure. Despite therapeutic advances aimed at slowing disease progression and alleviation of symptoms, the absence of curative treatments, together with a lack of precision medicine tools for accurate treatment response monitoring, poses a significant challenge for patient management. Addressing these needs necessitates a compre Show more