Publication: Synthesis of Poly-Aib Oligopeptides and Aib-Containing Peptides via the 'Azirine/Oxazolone Method', and their crystal structures
Date
Date
Date
2011
Journal Article
Published version
Abstract
Abstract
Abstract
The protected poly-Aib oligopeptides Z-(Aib)n-N(Me)Ph with n = 2 – 6 were prepared according to the 'azirine/oxazolone method', i.e., by coupling amino or peptide acids with 2,2,N-trimethyl-N-phenyl-2H-azirin-3-amine (1a) as an Aib synthon (Scheme 2). Following the same concept, the segments Z-(Aib)3-OH (9) and H-L-Pro-(Aib)3-N(Me)Ph (20) were synthesized, and their subsequent coupling with N,N’-dicyclohexylcarbodiimide (DCC)/ZnCl2 led to the protected heptapeptide Z-(Aib)3-L-Pro-(Aib)3-N(Me)Ph (21; Scheme 3). The crystal structures o
Additional indexing
Creators (Authors)
- Dannecker-Dörig, I
- Heimgartner, H
Volume
Volume
Volume
94
Number
Number
Number
6
Page range/Item number
Page range/Item number
Page range/Item number
993
Page end
Page end
Page end
1011
Item Type
Item Type
Item Type
Journal Article
In collections
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Dewey Decimal Classifikation
Language
Language
Language
English
Publication date
Publication date
Publication date
2011
Date available
Date available
Date available
2011-08-04
ISSN or e-ISSN
ISSN or e-ISSN
ISSN or e-ISSN
0018-019X
OA Status
OA Status
OA Status
Green
Publisher DOI
Green Open Access
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Permanent URL
Files
Files
Files
Files available to download:2
Files
Files
Files
Files available to download:2
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