Publication:

Targeting the interaction of GABA$_{B}$ receptors with CaMKII with an interfering peptide restores receptor expression after cerebral ischemia and inhibits progressive neuronal death in mouse brain cells and slices

Date

Date

Date
2023
Journal Article
Published version

Citations

Citation copied

Balakrishnan, K., Hleihil, M., Bhat, M. A., Ganley, R. P., Vaas, M., Klohs, J., Zeilhofer, H. U., & Benke, D. (2023). Targeting the interaction of GABA$_{B}$ receptors with CaMKII with an interfering peptide restores receptor expression after cerebral ischemia and inhibits progressive neuronal death in mouse brain cells and slices. Brain Pathology, 33(1), e13099. https://doi.org/10.1111/bpa.13099

Abstract

Abstract

Abstract

Cerebral ischemia is the leading cause for long-term disability and mortality in adults due to massive neuronal death. Currently, there is no pharmacological treatment available to limit progressive neuronal death after stroke. A major mechanism causing ischemia-induced neuronal death is the excessive release of glutamate and the associated overexcitation of neurons (excitotoxicity). Normally, GABA$_{B}$

Additional indexing

Creators (Authors)

  • Balakrishnan, Karthik
    affiliation.icon.alt
  • Hleihil, Mohammad
    affiliation.icon.alt
  • Bhat, Musadiq A
    affiliation.icon.alt
  • Ganley, Robert P
    affiliation.icon.alt
  • Vaas, Markus
    affiliation.icon.alt
  • Klohs, Jan
    affiliation.icon.alt
  • Benke, Dietmar
    affiliation.icon.alt

Journal/Series Title

Journal/Series Title

Journal/Series Title

Volume

Volume

Volume
33

Number

Number

Number
1

Page Range

Page Range

Page Range
e13099

Item Type

Item Type

Item Type
Journal Article

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Dewey Decimal Classifikation

Language

Language

Language
English

Publication date

Publication date

Publication date
2023-01-01

Date available

Date available

Date available
2022-08-02

Publisher

Publisher

Publisher

ISSN or e-ISSN

ISSN or e-ISSN

ISSN or e-ISSN
1015-6305

OA Status

OA Status

OA Status
Gold

Free Access at

Free Access at

Free Access at
Pubmed ID

PubMed ID

PubMed ID

PubMed ID

Citations

Citation copied

Balakrishnan, K., Hleihil, M., Bhat, M. A., Ganley, R. P., Vaas, M., Klohs, J., Zeilhofer, H. U., & Benke, D. (2023). Targeting the interaction of GABA$_{B}$ receptors with CaMKII with an interfering peptide restores receptor expression after cerebral ischemia and inhibits progressive neuronal death in mouse brain cells and slices. Brain Pathology, 33(1), e13099. https://doi.org/10.1111/bpa.13099

Gold Open Access
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