Publication: Scaffold, mechanics and functions of nuclear lamins
Scaffold, mechanics and functions of nuclear lamins
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Buxboim, A., Kronenberg-Tenga, R., Salajkova, S., Avidan, N., Shahak, H., Thurston, A., & Medalia, O. (2023). Scaffold, mechanics and functions of nuclear lamins. FEBS Letters, 597(22), 2791–2805. https://doi.org/10.1002/1873-3468.14750
Abstract
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Abstract
Nuclear lamins are type-V intermediate filaments that are involved in many nuclear processes. In mammals, A- and B-type lamins assemble into separate physical meshwork underneath the inner nuclear membrane, the nuclear lamina, with some residual fraction localized within the nucleoplasm. Lamins are the major part of the nucleoskeleton, providing mechanical strength and flexibility to protect the genome and allow nuclear deformability, while also contributing to gene regulation via interactions with chromatin. While lamins are the evol
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- Buxboim, Amnon
- Kronenberg-Tenga, Rafael
- Salajkova, Sarka
- Avidan, Nili
- Shahak, Hen
- Thurston, Alice
- Medalia, Ohad
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Buxboim, A., Kronenberg-Tenga, R., Salajkova, S., Avidan, N., Shahak, H., Thurston, A., & Medalia, O. (2023). Scaffold, mechanics and functions of nuclear lamins. FEBS Letters, 597(22), 2791–2805. https://doi.org/10.1002/1873-3468.14750
